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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:mifepristone
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Accession:CHEBI:50692 term browser browse the term
Definition:A 3-oxo steroid that has formula 429.59374.
Synonyms:exact_synonym: 11beta-[4-(dimethylamino)phenyl]-17beta-hydroxy-17alpha-(prop-1-yn-1-yl)estra-4,9-dien-3-one
 related_synonym: 11-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE;   Formula=C29H35NO2;   InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1;   InChIKey=VKHAHZOOUSRJNA-GCNJZUOMSA-N;   Mifegyne;   Mifeprex;   RU-486;   RU486;   SMILES=[H][C@@]12CCC3=CC(=O)CCC3=C1[C@H](C[C@@]1(C)[C@@]2([H])CC[C@@]1(O)C#CC)c1ccc(cc1)N(C)C;   mifepristona;   mifepristonum
 alt_id: CHEBI:40057;   CHEBI:6934
 xref: CAS:84371-65-3;   DrugBank:DB00834;   Drug_Central:1805;   KEGG:C07652;   KEGG:D00585;   LINCS:LSM-2822
 xref_mesh: MESH:D015735
 xref: PDBeChem:486;   Patent:EP57115;   Patent:US4386085


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mifepristone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 decreases expression EXP Mifepristone results in decreased expression of ABCA1 mRNA CTD PMID:25972201 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 increases expression
multiple interactions
decreases activity
ISO Mifepristone results in increased expression of ABCB11 mRNA
Mifepristone inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Mifepristone results in decreased activity of ABCB11 protein
CTD PMID:15456840, PMID:23956101, PMID:24014644 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
multiple interactions
ISO Mifepristone results in increased expression of ABCB1A mRNA
ABCB1 protein affects the reaction [Mifepristone results in decreased transport of calcein AM]
CTD PMID:15456840, PMID:30217652 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO Mifepristone results in increased expression of ABCC2 mRNA CTD PMID:15456840 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions
increases activity
increases expression
ISO [Mifepristone results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA
Mifepristone results in increased activity of ABCC3 protein
Mifepristone results in increased expression of ABCC3 mRNA
CTD PMID:14570758, PMID:15456840 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 decreases expression ISO Mifepristone results in decreased expression of ABCC8 mRNA CTD PMID:17584828 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO ABCG2 protein affects the reaction [Mifepristone results in decreased transport of pheophorbide a] CTD PMID:30217652 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Ablim1 actin-binding LIM protein 1 increases expression ISO Mifepristone results in increased expression of ABLIM1 mRNA CTD PMID:17584828 NCBI chr 1:277,853,877...278,043,096 JBrowse link
G Acan aggrecan multiple interactions EXP Mifepristone inhibits the reaction [Corticosterone results in decreased expression of ACAN mRNA] CTD PMID:32663519 NCBI chr 1:140,762,758...140,824,441
Ensembl chr 1:140,762,758...140,824,441
JBrowse link
G Ace angiotensin I converting enzyme multiple interactions EXP Mifepristone inhibits the reaction [Corticosterone results in increased expression of ACE mRNA]; Mifepristone inhibits the reaction [Dexamethasone results in increased expression of ACE mRNA] CTD PMID:15932931, PMID:30423288, PMID:32494933 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ackr1 atypical chemokine receptor 1 multiple interactions ISO Mifepristone inhibits the reaction [Hydrocortisone results in increased expression of ACKR1 mRNA] CTD PMID:25763180 NCBI chr13:91,827,310...91,828,875 JBrowse link
G Ackr3 atypical chemokine receptor 3 decreases expression ISO Mifepristone results in decreased expression of ACKR3 mRNA CTD PMID:17584828 NCBI chr 9:97,355,881...97,367,455
Ensembl chr 9:97,355,924...97,367,445
JBrowse link
G Acly ATP citrate lyase increases expression ISO Mifepristone results in increased expression of ACLY mRNA CTD PMID:17584828 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Acot1 acyl-CoA thioesterase 1 decreases expression EXP Mifepristone results in decreased expression of ACOT1 mRNA CTD PMID:25972201 NCBI chr 6:107,485,088...107,493,082
Ensembl chr 6:107,485,249...107,493,798
JBrowse link
G Actb actin, beta decreases expression ISO Mifepristone results in decreased expression of ACTB mRNA CTD PMID:17584828 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Adam15 ADAM metallopeptidase domain 15 decreases expression EXP Mifepristone results in decreased expression of ADAM15 mRNA CTD PMID:25972201 NCBI chr 2:188,661,831...188,672,337
Ensembl chr 2:188,661,699...188,672,247
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 multiple interactions
decreases expression
ISO
EXP
Mifepristone inhibits the reaction [Progesterone results in increased expression of ADAMTS1 mRNA]; Mifepristone inhibits the reaction [Progesterone results in increased expression of ADAMTS1 protein]
Mifepristone results in decreased expression of ADAMTS1 mRNA
CTD PMID:17018655, PMID:25972201 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 decreases expression EXP Mifepristone results in decreased expression of ADAMTS9 mRNA CTD PMID:25972201 NCBI chr 4:124,660,254...124,860,997
Ensembl chr 4:124,660,262...124,858,250
JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 decreases expression ISO Mifepristone results in decreased expression of ADGRG1 mRNA CTD PMID:17584828 NCBI chr19:10,423,534...10,460,674
Ensembl chr19:10,423,501...10,460,674
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) decreases expression EXP Mifepristone results in decreased expression of ADH1 mRNA CTD PMID:25972201 NCBI chr 2:243,550,655...243,562,243
Ensembl chr 2:243,550,627...243,687,857
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO Mifepristone inhibits the reaction [butylparaben results in increased expression of ADIPOQ mRNA]
Mifepristone inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]
CTD PMID:22956630, PMID:29782964 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adipor2 adiponectin receptor 2 multiple interactions ISO Mifepristone inhibits the reaction [rosiglitazone results in increased activity of ADIPOR2 promoter] CTD PMID:16609881 NCBI chr 4:151,412,135...151,480,108
Ensembl chr 4:151,414,684...151,428,894
JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions EXP Mifepristone inhibits the reaction [Dexamethasone results in increased expression of ADRB2 mRNA] CTD PMID:9074950 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions EXP Mifepristone inhibits the reaction [Corticosterone results in increased expression of AGTR1A mRNA] CTD PMID:30423288 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions EXP Mifepristone inhibits the reaction [Corticosterone results in increased expression of AGTR2 mRNA]; Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of AGTR2 mRNA] CTD PMID:30359671, PMID:30423288 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity
ISO
EXP
Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of AHR mRNA]; Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of AHR protein]
Mifepristone results in increased activity of AHR protein
Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR mRNA]]
Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin binds to AHR protein]]; Mifepristone inhibits the reaction [Dexamethasone results in increased expression of AHR mRNA]
CTD PMID:17690134, PMID:18086832, PMID:19022236, PMID:26187274 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 increases expression ISO Mifepristone results in increased expression of AIMP1 mRNA CTD PMID:17584828 NCBI chr 2:237,727,782...237,751,327
Ensembl chr 2:237,727,764...237,751,378
JBrowse link
G Ajuba ajuba LIM protein decreases expression EXP Mifepristone results in decreased expression of AJUBA mRNA CTD PMID:25972201 NCBI chr15:33,208,210...33,218,456
Ensembl chr15:33,208,216...33,218,456
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP Mifepristone inhibits the reaction [Dexamethasone results in decreased phosphorylation of AKT1 protein]; Mifepristone inhibits the reaction [Progesterone results in increased phosphorylation of AKT1 protein]; Mifepristone inhibits the reaction [Promegestone results in increased phosphorylation of AKT1 protein] CTD PMID:15187100, PMID:16020483, PMID:28324061 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aldh3b2 aldehyde dehydrogenase 3 family, member B2 decreases expression ISO Mifepristone results in decreased expression of ALDH3B2 mRNA CTD PMID:17584828 NCBI chr 1:219,215,023...219,218,488 JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression ISO Mifepristone results in decreased expression of ALDOC mRNA CTD PMID:17584828 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Angpt2 angiopoietin 2 decreases expression EXP Mifepristone results in decreased expression of ANGPT2 mRNA CTD PMID:25972201 NCBI chr16:75,966,480...76,016,147
Ensembl chr16:75,966,352...76,016,195
JBrowse link
G Ankrd10 ankyrin repeat domain 10 increases expression ISO Mifepristone results in increased expression of ANKRD10 mRNA CTD PMID:17584828 NCBI chr16:83,205,898...83,229,147
Ensembl chr16:83,206,004...83,228,194
JBrowse link
G Anpep alanyl aminopeptidase, membrane decreases expression ISO Mifepristone results in decreased expression of ANPEP mRNA CTD PMID:17584828 NCBI chr 1:141,561,364...141,604,249
Ensembl chr 1:141,561,334...141,604,273
JBrowse link
G Anxa1 annexin A1 increases expression
multiple interactions
ISO Mifepristone results in increased expression of ANXA1 mRNA
Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [EGFR protein binds to ANXA1 protein modified form]]; Mifepristone inhibits the reaction [Dexamethasone results in increased localization of ANXA1 protein modified form]; Mifepristone inhibits the reaction [Dexamethasone results in increased phosphorylation of and results in increased expression of ANXA1 protein]; Mifepristone inhibits the reaction [Hydrocortisone results in increased expression of ANXA1 mRNA]
CTD PMID:10807665, PMID:17584828, PMID:25763180 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Anxa3 annexin A3 decreases expression EXP Mifepristone results in decreased expression of ANXA3 mRNA CTD PMID:25972201 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G Aoc3 amine oxidase, copper containing 3 decreases expression EXP Mifepristone results in decreased expression of AOC3 mRNA CTD PMID:25972201 NCBI chr10:89,251,370...89,259,313
Ensembl chr10:89,251,370...89,259,313
JBrowse link
G Apob apolipoprotein B multiple interactions ISO Mifepristone inhibits the reaction [Hydrocortisone results in decreased expression of APOB mRNA] CTD PMID:31075344 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoc1 apolipoprotein C1 decreases expression ISO
EXP
Mifepristone results in decreased expression of APOC1 mRNA CTD PMID:17584828, PMID:25972201 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921
JBrowse link
G Ar androgen receptor multiple interactions
decreases activity
affects binding
ISO [Mifepristone binds to AR protein] promotes the reaction [CREBBP protein binds to KLK3 enhancer]; [Mifepristone binds to AR protein] promotes the reaction [CREBBP protein binds to KLK3 promoter]; [Mifepristone binds to AR protein] promotes the reaction [NCOA2 protein binds to KLK3 enhancer]; [Mifepristone binds to AR protein] promotes the reaction [NCOA2 protein binds to KLK3 promoter]; [Mifepristone binds to AR protein] promotes the reaction [NCOR1 protein binds to KLK3 promoter]; Mifepristone binds to and results in decreased activity of AR protein; Mifepristone binds to and results in decreased activity of AR protein mutant form; Mifepristone inhibits the reaction [Fludrocortisone results in increased activity of AR protein mutant form]; Mifepristone inhibits the reaction [Flutamide results in increased activity of AR protein mutant form]; Mifepristone inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]; Mifepristone inhibits the reaction [Metribolone results in increased activity of AR protein mutant form]; Mifepristone inhibits the reaction [Metribolone results in increased activity of AR protein]
Mifepristone results in decreased activity of AR protein
[Mifepristone binds to AR protein] which binds to KLK3 enhancer; [Mifepristone binds to AR protein] which binds to KLK3 promoter; Mifepristone binds to AR protein
CTD PMID:11956172, PMID:15308689, PMID:15589981, PMID:18324785, PMID:21543282, PMID:25752796 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Araf A-Raf proto-oncogene, serine/threonine kinase multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein promotes the reaction [EGFR protein binds to ARAF protein]]] CTD PMID:10807665 NCBI chr  X:1,369,534...1,391,603
Ensembl chr  X:1,379,194...1,390,873
JBrowse link
G Areg amphiregulin decreases expression EXP Mifepristone results in decreased expression of AREG mRNA CTD PMID:18591650 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arg1 arginase 1 multiple interactions EXP Mifepristone inhibits the reaction [Hydrocortisone results in increased expression of ARG1 mRNA] CTD PMID:26647222 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Arhgap28 Rho GTPase activating protein 28 increases expression ISO Mifepristone results in increased expression of ARHGAP28 mRNA CTD PMID:17584828 NCBI chr 9:116,057,229...116,222,440
Ensembl chr 9:116,058,610...116,222,440
JBrowse link
G Arl4d ADP-ribosylation factor like GTPase 4D decreases expression ISO Mifepristone results in decreased expression of ARL4D mRNA CTD PMID:17584828 NCBI chr10:89,577,556...89,580,368
Ensembl chr10:89,578,212...89,580,368
JBrowse link
G Arl6ip1 ADP-ribosylation factor like GTPase 6 interacting protein 1 increases expression ISO Mifepristone results in increased expression of ARL6IP1 mRNA CTD PMID:17584828 NCBI chr 1:187,770,160...187,779,675
Ensembl chr 1:187,770,160...187,779,675
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression EXP Mifepristone results in decreased expression of ASNS mRNA CTD PMID:25972201 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in increased expression of ATF3 mRNA] CTD PMID:15674352 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in decreased expression of ATP2A1 mRNA] CTD PMID:27264040 NCBI chr 1:197,855,912...197,875,038 JBrowse link
G Avp arginine vasopressin multiple interactions EXP Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of AVP mRNA] CTD PMID:32445661 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Axin2 axin 2 increases expression ISO Mifepristone results in increased expression of AXIN2 mRNA CTD PMID:17584828 NCBI chr10:97,212,483...97,238,824
Ensembl chr10:97,212,432...97,239,642
JBrowse link
G B3gat3 beta-1,3-glucuronyltransferase 3 decreases expression ISO Mifepristone results in decreased expression of B3GAT3 mRNA CTD PMID:17584828 NCBI chr 1:225,120,061...225,126,579
Ensembl chr 1:225,120,061...225,126,579
JBrowse link
G B3gnt6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 decreases expression ISO Mifepristone results in decreased expression of B3GNT6 mRNA CTD PMID:17584828 NCBI chr 1:163,143,027...163,149,496
Ensembl chr 1:163,143,917...163,148,948
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO
EXP
Mifepristone inhibits the reaction [Dexamethasone results in decreased phosphorylation of BAD protein]; Mifepristone inhibits the reaction [Dexamethasone results in increased expression of BAD mRNA]
Mifepristone inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Rotenone results in increased phosphorylation of BAD protein]]
CTD PMID:16644695, PMID:17123556 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects localization
increases expression
ISO Mifepristone affects the localization of BAX protein
Mifepristone results in increased expression of BAX mRNA; Mifepristone results in increased expression of BAX protein
CTD PMID:16009178, PMID:16638347 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 decreases expression ISO Mifepristone results in decreased expression of BCAT2 mRNA CTD PMID:17584828 NCBI chr 1:101,553,900...101,572,103
Ensembl chr 1:101,554,642...101,572,080
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO Mifepristone inhibits the reaction [Dexamethasone results in increased expression of BCL2]
Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of BCL2 mRNA]; Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of BCL2 protein]
Mifepristone results in decreased expression of BCL2 mRNA; Mifepristone results in decreased expression of BCL2 protein
CTD PMID:16009178, PMID:16525653, PMID:16638347, PMID:16644695, PMID:21244764 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions EXP Mifepristone affects the reaction [Dexamethasone inhibits the reaction [Camptothecin results in decreased expression of BCL2L1 protein alternative form]]; Mifepristone inhibits the reaction [Corticosterone results in increased expression of BCL2L1 protein]; Mifepristone inhibits the reaction [Dexamethasone results in increased expression of BCL2L1 protein]; Mifepristone inhibits the reaction [Progesterone results in increased expression of BCL2L1 protein]; Mifepristone promotes the reaction [Tretinoin results in increased expression of BCL2L1 mRNA] CTD PMID:15755911, PMID:17635642, PMID:19339209, PMID:20726854, PMID:26915917 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression
multiple interactions
ISO
EXP
Mifepristone results in decreased expression of BDNF protein
Mifepristone inhibits the reaction [Dexamethasone results in decreased acetylation of BDNF exon]; Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of BDNF mRNA]
CTD PMID:17464718, PMID:31518422 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO Mifepristone results in increased expression of BID mRNA CTD PMID:17584828 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone results in increased expression of BIRC5] CTD PMID:21244764 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bnip2 BCL2 interacting protein 2 increases expression ISO Mifepristone results in increased expression of BNIP2 mRNA CTD PMID:17584828 NCBI chr 8:76,400,333...76,426,307
Ensembl chr 8:76,400,341...76,426,503
JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin decreases expression ISO Mifepristone results in decreased expression of BSCL2 mRNA CTD PMID:17584828 NCBI chr 1:225,035,956...225,046,137
Ensembl chr 1:225,037,737...225,046,040
JBrowse link
G Btk Bruton tyrosine kinase increases expression ISO Mifepristone results in increased expression of BTK mRNA CTD PMID:17584828 NCBI chr  X:105,360,922...105,390,580
Ensembl chr  X:105,360,922...105,390,580
JBrowse link
G C1qtnf6 C1q and TNF related 6 increases expression ISO Mifepristone results in increased expression of C1QTNF6 mRNA CTD PMID:17584828 NCBI chr 7:119,746,150...119,752,727
Ensembl chr 7:119,746,118...119,753,290
JBrowse link
G C3 complement C3 multiple interactions EXP Mifepristone inhibits the reaction [Medroxyprogesterone Acetate inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA]]; Mifepristone inhibits the reaction [Triclosan results in increased expression of C3 mRNA]; Mifepristone promotes the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA] CTD PMID:11566438, PMID:16806946, PMID:22062131 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Ca12 carbonic anhydrase 12 multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Genistein results in increased expression of CA12 mRNA]] CTD PMID:25136773 NCBI chr 8:72,405,770...72,461,425
Ensembl chr 8:72,405,748...72,460,240
JBrowse link
G Cabin1 calcineurin binding protein 1 increases expression ISO Mifepristone results in increased expression of CABIN1 mRNA CTD PMID:17584828 NCBI chr20:13,836,032...13,963,003
Ensembl chr20:13,836,030...13,963,003
JBrowse link
G Calm2 calmodulin 2 multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in decreased expression of CALM2 mRNA] CTD PMID:27264040 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Camp cathelicidin antimicrobial peptide decreases expression ISO Mifepristone results in decreased expression of CAMP protein CTD PMID:17701593 NCBI chr 8:117,930,557...117,932,371
Ensembl chr 8:117,930,546...117,932,518
JBrowse link
G Capn5 calpain 5 decreases expression ISO Mifepristone results in decreased expression of CAPN5 mRNA CTD PMID:17584828 NCBI chr 1:163,073,134...163,129,736
Ensembl chr 1:163,073,124...163,129,641
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
decreases expression
ISO
EXP
[Etoposide co-treated with Mifepristone] results in increased activity of CASP3 protein; [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of CASP3 mRNA]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [TNFSF10 protein results in increased activity of CASP3 protein]]; Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP3 protein]]
Mifepristone inhibits the reaction [Corticosterone inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]]; Mifepristone inhibits the reaction [Progesterone inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]]
Mifepristone results in increased activity of CASP3 protein
Mifepristone inhibits the reaction [Dexamethasone results in increased activity of CASP3 protein]
Mifepristone results in decreased expression of CASP3 protein
CTD PMID:12645856, PMID:15755911, PMID:16525653, PMID:16644695, PMID:17070682, PMID:20726854, PMID:22736252, PMID:26915917, PMID:30217652 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [TNFSF10 protein results in increased activity of CASP8 protein]]; Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein]] CTD PMID:12645856, PMID:17070682 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of CASP9 mRNA] CTD PMID:22736252 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions ISO
EXP
[Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in decreased activity of CAT protein]
[Mifepristone co-treated with Paraquat] results in decreased activity of CAT protein; NFE2L2 protein inhibits the reaction [[Mifepristone co-treated with Paraquat] results in decreased activity of CAT protein]
CTD PMID:22736252, PMID:24812154 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in increased expression of CAV1 mRNA] CTD PMID:15674352 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Ccdc80 coiled-coil domain containing 80 decreases expression EXP Mifepristone results in decreased expression of CCDC80 mRNA CTD PMID:25972201 NCBI chr11:60,645,660...60,679,249
Ensembl chr11:60,645,086...60,679,555
JBrowse link
G Ccl12 chemokine (C-C motif) ligand 12 decreases expression ISO Mifepristone results in decreased expression of CCL13 mRNA CTD PMID:17584828 NCBI chr10:69,476,866...69,478,416
Ensembl chr10:69,476,775...69,478,462
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases expression
EXP [Mifepristone binds to and results in decreased activity of PGR protein] which results in increased expression of CCL2 mRNA; [Mifepristone binds to and results in decreased activity of PGR protein] which results in increased expression of CCL2 protein
Mifepristone results in decreased expression of CCL2 mRNA
CTD PMID:18606702, PMID:25972201 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression ISO Mifepristone results in decreased expression of CCL3 mRNA CTD PMID:17584828 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression EXP Mifepristone results in decreased expression of CCN2 mRNA CTD PMID:25972201 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Mifepristone results in decreased expression of CCNA2 protein CTD PMID:17545545 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of CCND1 protein] CTD PMID:18097517 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 multiple interactions ISO Mifepristone inhibits the reaction [CDK2 protein binds to CCNE1 protein]; Mifepristone results in decreased expression of and results in decreased localization of CCNE1 protein CTD PMID:17545545 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cd24 CD24 molecule decreases expression EXP Mifepristone results in decreased expression of CD24 mRNA CTD PMID:25972201 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
G Cd28 Cd28 molecule multiple interactions ISO Mifepristone inhibits the reaction [[Dexamethasone co-treated with CD28 protein] results in increased expression of NFKBIA mRNA]; Mifepristone inhibits the reaction [[rimexolone co-treated with CD28 protein] results in increased expression of NFKBIA mRNA]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [CD28 protein results in increased secretion of IFNG protein]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [CD28 protein results in increased secretion of IL2 protein]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [CD28 protein results in increased secretion of TNF protein]]; Mifepristone inhibits the reaction [rimexolone inhibits the reaction [CD28 protein results in increased secretion of IFNG protein]]; Mifepristone inhibits the reaction [rimexolone inhibits the reaction [CD28 protein results in increased secretion of IL2 protein]]; Mifepristone inhibits the reaction [rimexolone inhibits the reaction [CD28 protein results in increased secretion of TNF protein]] CTD PMID:20363256 NCBI chr 9:67,546,408...67,573,858
Ensembl chr 9:67,546,408...67,571,871
JBrowse link
G Cd36 CD36 molecule decreases expression ISO Mifepristone results in decreased expression of CD36 mRNA CTD PMID:17584828 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd4 Cd4 molecule multiple interactions
decreases expression
ISO Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of CD4 protein]; Mifepristone inhibits the reaction [rimexolone results in decreased expression of CD4 protein]
Mifepristone results in decreased expression of CD4 protein
CTD PMID:20363256 NCBI chr 4:157,381,862...157,408,357
Ensembl chr 4:157,383,052...157,408,176
JBrowse link
G Cd69 Cd69 molecule increases expression ISO Mifepristone results in increased expression of CD69 mRNA CTD PMID:17584828 NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084
JBrowse link
G Cdc25b cell division cycle 25B decreases expression EXP Mifepristone results in decreased expression of CDC25B mRNA CTD PMID:25972201 NCBI chr 3:123,731,539...123,741,696
Ensembl chr 3:123,731,539...123,741,339
JBrowse link
G Cdc25c cell division cycle 25C multiple interactions ISO Mifepristone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of CDC25C protein] CTD PMID:22266097 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdh1 cadherin 1 increases expression ISO Mifepristone results in increased expression of CDH1 mRNA CTD PMID:17584828 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh11 cadherin 11 increases expression ISO Mifepristone results in increased expression of CDH11 mRNA CTD PMID:17584828 NCBI chr19:2,391,181...2,551,245
Ensembl chr19:2,393,059...2,551,245
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression
multiple interactions
decreases expression
ISO Mifepristone results in increased expression of CDK1 mRNA
Mifepristone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of CDK1 protein]
Mifepristone results in decreased expression of CDK1 protein
CTD PMID:17545545, PMID:17584828, PMID:22266097 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO Mifepristone inhibits the reaction [CDK2 protein binds to CCNE1 protein]; Mifepristone promotes the reaction [CDK2 protein binds to CDKN1B protein]; Mifepristone promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein]; Mifepristone promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein]; Mifepristone results in decreased localization of and results in decreased expression of CDK2 protein CTD PMID:17545545 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO Mifepristone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDKN1A protein]; Mifepristone promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein]; Mifepristone results in increased expression of and results in increased localization of CDKN1A protein CTD PMID:17545545, PMID:22266097 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO Mifepristone inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol] results in increased expression of CDKN1B protein]; Mifepristone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDKN1B protein]; Mifepristone promotes the reaction [CDK2 protein binds to CDKN1B protein]; Mifepristone promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein]; Mifepristone results in increased expression of and results in increased localization of CDKN1B protein CTD PMID:17283133, PMID:17545545, PMID:22266097 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO Mifepristone inhibits the reaction [bisphenol A results in increased expression of CEBPA mRNA]; Mifepristone inhibits the reaction [butylparaben results in increased expression of CEBPA mRNA]
Mifepristone inhibits the reaction [Hydrocortisone results in increased expression of CEBPA mRNA]
CTD PMID:22956630, PMID:27145005, PMID:30528684 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions EXP
ISO
Mifepristone promotes the reaction [CEBPB protein binds to NR3C1 protein]
Mifepristone affects the reaction [Hydrocortisone affects the expression of CEBPB mRNA]
CTD PMID:18650268, PMID:30528684 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cfb complement factor B decreases expression EXP Mifepristone results in decreased expression of CFB mRNA CTD PMID:25972201 NCBI chr20:4,536,206...4,542,073
Ensembl chr20:4,536,203...4,561,066
Ensembl chr20:4,536,203...4,561,066
JBrowse link
G Cfd complement factor D increases expression ISO Mifepristone results in increased expression of CFD protein CTD PMID:26018136 NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions
decreases expression
ISO
EXP
Mifepristone inhibits the reaction [Dexamethasone results in increased expression of CFLAR]; Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of CFLAR protein modified form]]
Mifepristone results in decreased expression of CFLAR mRNA
CTD PMID:12645856, PMID:21244764, PMID:25972201 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in increased phosphorylation of CHEK1 protein] CTD PMID:22403396 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 decreases expression EXP Mifepristone results in decreased expression of CITED1 mRNA CTD PMID:25972201 NCBI chr  X:72,128,996...72,133,692
Ensembl chr  X:72,128,994...72,133,692
JBrowse link
G Ckb creatine kinase B decreases expression ISO Mifepristone results in decreased expression of CKB mRNA CTD PMID:17584828 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
JBrowse link
G Cldn1 claudin 1 decreases expression EXP Mifepristone results in decreased expression of CLDN1 mRNA CTD PMID:25972201 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Cldn11 claudin 11 decreases expression EXP Mifepristone results in decreased expression of CLDN11 mRNA CTD PMID:25972201 NCBI chr 2:115,823,541...115,836,846
Ensembl chr 2:115,823,538...115,836,846
JBrowse link
G Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 increases expression ISO Mifepristone results in increased expression of CMTM6 mRNA CTD PMID:17584828 NCBI chr 8:122,789,208...122,807,560
Ensembl chr 8:122,789,453...122,807,560
JBrowse link
G Cntnap1 contactin associated protein 1 decreases expression ISO Mifepristone results in decreased expression of CNTNAP1 mRNA CTD PMID:17584828 NCBI chr10:89,087,904...89,103,615
Ensembl chr10:89,089,646...89,103,614
JBrowse link
G Col12a1 collagen type XII alpha 1 chain decreases expression EXP Mifepristone results in decreased expression of COL12A1 mRNA CTD PMID:25972201 NCBI chr 8:87,042,820...87,150,701
Ensembl chr 8:87,040,799...87,158,368
JBrowse link
G Col13a1 collagen type XIII alpha 1 chain decreases expression EXP Mifepristone results in decreased expression of COL13A1 mRNA CTD PMID:25972201 NCBI chr20:31,456,502...31,598,360
Ensembl chr20:31,456,852...31,598,118
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression EXP Mifepristone results in decreased expression of COL1A1 mRNA CTD PMID:25972201 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression EXP Mifepristone results in decreased expression of COL1A2 mRNA CTD PMID:25972201 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Col2a1 collagen type II alpha 1 chain decreases expression
multiple interactions
ISO
EXP
Mifepristone results in decreased expression of COL2A1 mRNA
Mifepristone inhibits the reaction [Corticosterone results in decreased expression of COL2A1 mRNA]
CTD PMID:17584828, PMID:32663519 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression EXP Mifepristone results in decreased expression of COL3A1 mRNA CTD PMID:25972201 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Col4a5 collagen type IV alpha 5 chain decreases expression ISO Mifepristone results in decreased expression of COL4A5 mRNA CTD PMID:17584828 NCBI chr  X:112,769,595...112,983,720
Ensembl chr  X:112,769,645...112,983,685
JBrowse link
G Col4a6 collagen type IV alpha 6 chain decreases expression ISO Mifepristone results in decreased expression of COL4A6 mRNA CTD PMID:17584828 NCBI chr  X:112,405,647...112,768,337
Ensembl chr  X:112,405,647...112,473,822
JBrowse link
G Col5a3 collagen type V alpha 3 chain decreases expression EXP Mifepristone results in decreased expression of COL5A3 mRNA CTD PMID:25972201 NCBI chr 8:21,786,324...21,831,751
Ensembl chr 8:21,786,324...21,831,668
JBrowse link
G Comp cartilage oligomeric matrix protein decreases expression EXP Mifepristone results in decreased expression of COMP mRNA CTD PMID:25972201 NCBI chr16:20,798,437...20,807,070
Ensembl chr16:20,798,437...20,807,070
JBrowse link
G Cort cortistatin multiple interactions EXP Mifepristone inhibits the reaction [CORT protein results in increased expression of TNFRSF11B mRNA] CTD PMID:27338645 NCBI chr 5:165,942,780...165,944,221 JBrowse link
G Cp ceruloplasmin multiple interactions ISO Mifepristone inhibits the reaction [Progesterone affects the expression of CP mRNA] CTD PMID:22414680 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Cpe carboxypeptidase E decreases expression EXP Mifepristone results in decreased expression of CPE mRNA CTD PMID:25972201 NCBI chr16:26,906,716...27,014,811
Ensembl chr16:26,906,716...27,014,813
JBrowse link
G Cpz carboxypeptidase Z increases expression ISO Mifepristone results in increased expression of CPZ mRNA CTD PMID:17584828 NCBI chr14:80,402,946...80,426,203
Ensembl chr14:80,403,001...80,426,245
JBrowse link
G Crebbp CREB binding protein multiple interactions ISO [Mifepristone binds to AR protein] promotes the reaction [CREBBP protein binds to KLK3 enhancer]; [Mifepristone binds to AR protein] promotes the reaction [CREBBP protein binds to KLK3 promoter] CTD PMID:15308689 NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039
JBrowse link
G Crh corticotropin releasing hormone multiple interactions EXP Mifepristone inhibits the reaction [Ethanol results in increased expression of CRH mRNA] CTD PMID:22039522 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 decreases expression ISO Mifepristone results in decreased expression of CRISPLD2 mRNA CTD PMID:17584828 NCBI chr19:52,647,038...52,705,118
Ensembl chr19:52,647,070...52,705,131
JBrowse link
G Cryab crystallin, alpha B decreases expression EXP Mifepristone results in decreased expression of CRYAB mRNA CTD PMID:25972201 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Cst7 cystatin F decreases expression ISO Mifepristone results in decreased expression of CST7 mRNA CTD PMID:17584828 NCBI chr 3:146,363,913...146,373,365
Ensembl chr 3:146,365,092...146,373,365
JBrowse link
G Ctnnal1 catenin alpha-like 1 increases expression ISO Mifepristone results in increased expression of CTNNAL1 mRNA CTD PMID:17584828 NCBI chr 5:73,561,249...73,621,070
Ensembl chr 5:73,561,450...73,621,070
JBrowse link
G Ctnnb1 catenin beta 1 increases expression ISO Mifepristone results in increased expression of CTNNB1 mRNA CTD PMID:17584828 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctsc cathepsin C decreases expression EXP Mifepristone results in decreased expression of CTSC mRNA CTD PMID:25972201 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Ctss cathepsin S decreases expression EXP Mifepristone results in decreased expression of CTSS mRNA CTD PMID:25972201 NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression ISO Mifepristone results in increased expression of CX3CL1 mRNA CTD PMID:17584828 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cxadr CXADR, Ig-like cell adhesion molecule decreases expression EXP Mifepristone results in decreased expression of CXADR mRNA CTD PMID:25972201 NCBI chr11:16,826,269...16,873,564
Ensembl chr11:16,826,399...16,873,562
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression ISO Mifepristone results in decreased expression of CXCL1 mRNA CTD PMID:17584828 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO Mifepristone results in increased expression of CXCL12 mRNA CTD PMID:17584828 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 decreases expression ISO Mifepristone results in decreased expression of CXCL13 mRNA CTD PMID:17584828 NCBI chr14:15,253,146...15,258,221
Ensembl chr14:15,253,125...15,258,207
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO Mifepristone inhibits the reaction [Halothane results in increased expression of CXCL2 mRNA]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [Halothane results in increased expression of CXCL2 mRNA]] CTD PMID:21501669, PMID:22157104 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression
multiple interactions
ISO Mifepristone results in decreased expression of CXCL1 mRNA
Mifepristone inhibits the reaction [Halothane results in increased expression of CXCL1 mRNA]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [Halothane results in increased expression of CXCL1 mRNA]]; Mifepristone inhibits the reaction [Progesterone results in increased expression of CXCL1 mRNA]
CTD PMID:17584828, PMID:21501669, PMID:22157104 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression EXP Mifepristone results in decreased expression of CXCR4 mRNA CTD PMID:25972201 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of CYCS mRNA] CTD PMID:22736252 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO
EXP
[Dexamethasone co-treated with Mifepristone] promotes the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; [Dexamethasone co-treated with Mifepristone] results in increased activity of CYP1A1 protein
Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]]
Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [benz(a)anthracene results in increased activity of CYP1A1 protein]]; Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]]; Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]]
CTD PMID:7587946, PMID:17690134, PMID:19022236 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO
EXP
[Dexamethasone co-treated with Mifepristone] promotes the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein]; [Dexamethasone co-treated with Mifepristone] results in increased activity of CYP1A2 protein; Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]]; Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]] CTD PMID:17690134, PMID:19022236 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions EXP Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]; Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]] CTD PMID:9804617, PMID:17690134 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Mifepristone results in increased expression of CYP2B1 mRNA CTD PMID:16125621 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP Mifepristone results in increased expression of CYP2B2 mRNA CTD PMID:16125621 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO [Mifepristone results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA CTD PMID:17041008 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP Mifepristone results in increased expression of CYP3A23-3A1 mRNA CTD PMID:16125621 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO Mifepristone inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA]; Mifepristone inhibits the reaction [Budesonide results in increased expression of CYP3A5 mRNA]; Mifepristone inhibits the reaction [Dexamethasone results in increased expression of CYP3A5 mRNA] CTD PMID:12538830 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 decreases expression ISO Mifepristone results in decreased expression of CYP4B1 mRNA CTD PMID:17584828 NCBI chr 5:134,508,728...134,526,103
Ensembl chr 5:134,508,730...134,526,089
JBrowse link
G Dcn decorin increases expression ISO Mifepristone results in increased expression of DCN mRNA CTD PMID:17584828 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 decreases expression
multiple interactions
ISO
EXP
Mifepristone results in decreased expression of DDIT4 mRNA
Mifepristone inhibits the reaction [Dexamethasone results in increased expression of DDIT4 mRNA]
CTD PMID:17584828, PMID:20032058 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 decreases expression EXP Mifepristone results in decreased expression of DDR1 mRNA CTD PMID:25972201 NCBI chr20:3,553,430...3,574,959
Ensembl chr20:3,552,929...3,575,780
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 decreases expression EXP Mifepristone results in decreased expression of DDR2 mRNA CTD PMID:25972201 NCBI chr13:88,311,639...88,436,561
Ensembl chr13:88,317,145...88,436,789
JBrowse link
G Depp1 DEPP1, autophagy regulator multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in increased expression of DEPP1 mRNA] CTD PMID:16123073 NCBI chr 4:148,780,330...148,784,566
Ensembl chr 4:148,782,479...148,784,562
JBrowse link
G Dgcr8 DGCR8 microprocessor complex subunit multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone results in increased expression of DGCR8 mRNA] CTD PMID:32234517 NCBI chr11:86,852,682...86,885,233
Ensembl chr11:86,852,711...86,885,224
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 multiple interactions ISO Mifepristone promotes the reaction [Progesterone affects the expression of DHRS3 mRNA] CTD PMID:22414680 NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383
JBrowse link
G Dio2 iodothyronine deiodinase 2 increases expression
multiple interactions
ISO
EXP
Mifepristone results in increased expression of DIO2 mRNA
Mifepristone inhibits the reaction [Glucocorticoids promotes the reaction [Lipopolysaccharides results in increased activity of DIO2 protein]]; Mifepristone inhibits the reaction [Glucocorticoids promotes the reaction [Lipopolysaccharides results in increased expression of DIO2 mRNA]]; Mifepristone inhibits the reaction [Glucocorticoids results in increased activity of DIO2 protein]; Mifepristone inhibits the reaction [Glucocorticoids results in increased expression of DIO2 mRNA]
CTD PMID:17584828, PMID:21068073 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone results in increased expression of DKK1 mRNA]; Mifepristone inhibits the reaction [Progesterone results in increased expression of DKK1 mRNA]; Mifepristone inhibits the reaction [Progesterone results in increased expression of DKK1 protein]
Mifepristone inhibits the reaction [Corticosterone results in increased expression of DKK1 protein]
CTD PMID:16449346, PMID:21304589, PMID:22048647 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in increased expression of DLC1 mRNA] CTD PMID:15674352 NCBI chr16:58,776,489...59,247,752
Ensembl chr16:59,077,574...59,247,754
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Mifepristone results in increased expression of DNAJB9 mRNA CTD PMID:17584828 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Dpep1 dipeptidase 1 decreases expression EXP Mifepristone results in decreased expression of DPEP1 mRNA CTD PMID:25972201 NCBI chr19:55,973,447...55,998,830
Ensembl chr19:55,982,740...55,998,208
JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression EXP Mifepristone results in decreased expression of DUSP1 mRNA CTD PMID:25972201 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO Mifepristone results in decreased expression of E2F1 protein CTD PMID:17545545 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Edn2 endothelin 2 decreases expression EXP Mifepristone results in decreased expression of EDN2 mRNA CTD PMID:25972201 NCBI chr 5:139,098,472...139,106,396
Ensembl chr 5:139,100,898...139,105,792
JBrowse link
G Ednra endothelin receptor type A decreases expression EXP Mifepristone results in decreased expression of EDNRA mRNA CTD PMID:25972201 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Ednrb endothelin receptor type B increases expression ISO Mifepristone results in increased expression of EDNRB mRNA CTD PMID:17584828 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Efna1 ephrin A1 decreases expression EXP Mifepristone results in decreased expression of EFNA1 mRNA CTD PMID:25972201 NCBI chr 2:188,588,808...188,596,156
Ensembl chr 2:188,588,796...188,596,222
JBrowse link
G Egf epidermal growth factor multiple interactions
decreases expression
ISO
EXP
Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein promotes the reaction [EGFR protein binds to ARAF protein]]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein promotes the reaction [EGFR protein binds to GRB2 protein]]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein promotes the reaction [EGFR protein binds to HRAS protein]]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein results in increased phosphorylation of MAP2K1 protein]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein results in increased phosphorylation of MAPK8 protein]]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]]
Mifepristone results in decreased expression of EGF mRNA
CTD PMID:10807665, PMID:16175315, PMID:18591650 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
decreases expression
ISO
EXP
Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein promotes the reaction [EGFR protein binds to ARAF protein]]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein promotes the reaction [EGFR protein binds to GRB2 protein]]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein promotes the reaction [EGFR protein binds to HRAS protein]]]; Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [EGFR protein binds to ANXA1 protein modified form]]
Mifepristone results in decreased expression of EGFR mRNA
CTD PMID:10807665, PMID:18591650, PMID:25972201 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO Mifepristone inhibits the reaction [Progesterone inhibits the reaction [bisphenol A results in increased expression of EGR1 mRNA]]; Mifepristone inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of EGR1 mRNA]] CTD PMID:25461906 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Elf5 E74 like ETS transcription factor 5 multiple interactions ISO Mifepristone inhibits the reaction [16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased expression of ELF5 protein] CTD PMID:20519331 NCBI chr 3:93,333,514...93,374,454
Ensembl chr 3:93,351,619...93,371,656
JBrowse link
G Eln elastin decreases expression EXP Mifepristone results in decreased expression of ELN mRNA CTD PMID:25972201 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863
JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression ISO Mifepristone results in increased expression of ENC1 mRNA CTD PMID:17584828 NCBI chr 2:28,049,217...28,061,023
Ensembl chr 2:28,049,217...28,061,029
JBrowse link
G Eng endoglin multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in increased expression of ENG mRNA] CTD PMID:20431248 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Eno2 enolase 2 decreases expression EXP Mifepristone results in decreased expression of ENO2 mRNA CTD PMID:25972201 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions EXP Mifepristone inhibits the reaction [Dexamethasone results in increased expression of EP300 mRNA] CTD PMID:32494933 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 increases expression ISO Mifepristone results in increased expression of EPB41L3 mRNA CTD PMID:17584828 NCBI chr 9:117,314,935...117,666,408
Ensembl chr 9:117,538,009...117,666,410
JBrowse link
G Esm1 endothelial cell-specific molecule 1 increases expression ISO Mifepristone results in increased expression of ESM1 mRNA CTD PMID:17584828 NCBI chr 2:45,104,392...45,113,130
Ensembl chr 2:45,104,305...45,113,131
JBrowse link
G Esr1 estrogen receptor 1 increases expression EXP Mifepristone results in increased expression of ESR1 mRNA CTD PMID:20686183 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 affects expression
multiple interactions
EXP
ISO
Mifepristone affects the expression of ESR2 mRNA
Mifepristone binds to and results in decreased activity of ESR2 protein
CTD PMID:20686183, PMID:25752796 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Exosc5 exosome component 5 decreases expression ISO Mifepristone results in decreased expression of EXOSC5 mRNA CTD PMID:17584828 NCBI chr 1:82,452,104...82,461,607
Ensembl chr 1:82,452,469...82,461,606
JBrowse link
G F13a1 coagulation factor XIII A1 chain increases expression ISO Mifepristone results in increased expression of F13A1 mRNA CTD PMID:17584828 NCBI chr17:28,504,650...28,680,015
Ensembl chr17:28,504,623...28,680,362
JBrowse link
G F2r coagulation factor II (thrombin) receptor multiple interactions EXP Mifepristone inhibits the reaction [Dexamethasone results in increased expression of F2R mRNA]; Mifepristone inhibits the reaction [etonogestrel results in increased expression of F2R mRNA]; Mifepristone inhibits the reaction [Medroxyprogesterone Acetate results in increased expression of F2R mRNA] CTD PMID:11733402 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions
decreases expression
ISO
EXP
Mifepristone inhibits the reaction [Progesterone results in increased expression of F3 protein]
Mifepristone results in decreased expression of F3 mRNA
CTD PMID:15562024, PMID:25972201 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression
multiple interactions
ISO Mifepristone results in increased expression of FABP4 protein
Mifepristone inhibits the reaction [bisphenol A results in increased expression of FABP4 mRNA]
[Mifepristone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein; Mifepristone inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein]; Mifepristone inhibits the reaction [Dexamethasone results in increased expression of FABP4 protein]
CTD PMID:24418828, PMID:26018136, PMID:27003841, PMID:27145005, PMID:29782964 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fah fumarylacetoacetate hydrolase decreases expression ISO Mifepristone results in decreased expression of FAH mRNA CTD PMID:17584828 NCBI chr 1:146,713,663...146,736,339
Ensembl chr 1:146,713,676...146,736,261
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP3 protein]]; Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein]]; Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of CFLAR protein modified form]]; Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein]] CTD PMID:12645856 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand multiple interactions
increases expression
ISO Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein]]
Mifepristone results in increased expression of FASLG mRNA
CTD PMID:12645856, PMID:16009178 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO Mifepristone inhibits the reaction [Norethynodrel results in increased activity of FASN protein] CTD PMID:15870863 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbln1 fibulin 1 multiple interactions
decreases expression
ISO Mifepristone inhibits the reaction [Medroxyprogesterone Acetate results in increased expression of FBLN1 mRNA]
Mifepristone results in decreased expression of FBLN1 mRNA
CTD PMID:15774544, PMID:17584828 NCBI chr 7:126,096,793...126,176,468
Ensembl chr 7:126,096,793...126,176,468
JBrowse link
G Fbxo46 F-box protein 46 decreases expression ISO Mifepristone results in decreased expression of FBXO46 mRNA CTD PMID:17584828 NCBI chr 1:80,028,873...80,045,666
Ensembl chr 1:80,028,928...80,045,341
JBrowse link
G Fgf21 fibroblast growth factor 21 multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone results in increased expression of FGF21 mRNA] CTD PMID:28088388 NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 decreases expression EXP Mifepristone results in decreased expression of FGFR2 mRNA CTD PMID:25972201 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone results in increased expression of FKBP5 mRNA] CTD PMID:17690134 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020
JBrowse link
G Flrt2 fibronectin leucine rich transmembrane protein 2 decreases expression ISO Mifepristone results in decreased expression of FLRT2 mRNA CTD PMID:17584828 NCBI chr 6:119,518,459...119,613,534
Ensembl chr 6:119,519,714...119,609,296
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression EXP Mifepristone results in decreased expression of FLT1 mRNA CTD PMID:25972201 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression EXP Mifepristone results in decreased expression of FOS mRNA CTD PMID:25972201 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxn3 forkhead box N3 increases expression ISO Mifepristone results in increased expression of FOXN3 mRNA CTD PMID:17584828 NCBI chr 6:123,183,720...123,577,719
Ensembl chr 6:123,187,726...123,577,695
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO Mifepristone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of FOXO3 protein] CTD PMID:22266097 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Foxq1 forkhead box Q1 multiple interactions EXP Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of FOXQ1 mRNA]] CTD PMID:17690134 NCBI chr17:34,224,308...34,226,941
Ensembl chr17:34,224,818...34,226,453
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP Mifepristone promotes the reaction [[Tetrachlorodibenzodioxin co-treated with Gonadotropins, Equine] results in increased expression of FSHB protein] CTD PMID:12606454 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Fstl3 follistatin like 3 decreases expression ISO
EXP
Mifepristone results in decreased expression of FSTL3 mRNA CTD PMID:17584828, PMID:25972201 NCBI chr 7:12,806,031...12,810,556
Ensembl chr 7:12,804,919...12,810,570
JBrowse link
G Fzd10 frizzled class receptor 10 increases expression ISO Mifepristone results in increased expression of FZD10 mRNA CTD PMID:17584828 NCBI chr12:31,757,407...31,760,604
Ensembl chr12:31,757,407...31,760,604
JBrowse link
G Fzd4 frizzled class receptor 4 increases expression ISO Mifepristone results in increased expression of FZD4 mRNA CTD PMID:17584828 NCBI chr 1:153,589,471...153,598,376
Ensembl chr 1:153,589,471...153,598,375
JBrowse link
G Fzd6 frizzled class receptor 6 increases expression ISO Mifepristone results in increased expression of FZD6 mRNA CTD PMID:17584828 NCBI chr 7:77,898,329...77,931,034
Ensembl chr 7:77,899,322...77,931,029
JBrowse link
G Fzd9 frizzled class receptor 9 increases expression ISO Mifepristone results in increased expression of FZD9 mRNA CTD PMID:17584828 NCBI chr12:24,473,981...24,476,295
Ensembl chr12:24,473,981...24,476,295
JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions EXP Mifepristone inhibits the reaction [Dexamethasone results in increased expression of GAD1 mRNA] CTD PMID:32445661 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gata4 GATA binding protein 4 multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in decreased expression of GATA4 mRNA] CTD PMID:27264040 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
increases expression
ISO Acetaminophen promotes the reaction [Mifepristone results in increased activity of [GCLC protein binds to GCLM protein]]; Mifepristone results in increased activity of [GCLC protein binds to GCLM protein]
Mifepristone results in increased expression of GCLC protein
CTD PMID:16840778 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression
multiple interactions
ISO Mifepristone results in increased expression of GCLM protein
Acetaminophen promotes the reaction [Mifepristone results in increased activity of [GCLC protein binds to GCLM protein]]; Mifepristone results in increased activity of [GCLC protein binds to GCLM protein]
CTD PMID:16840778 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions EXP Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of GDNF mRNA] CTD PMID:30359671 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Ggta1 glycoprotein, alpha-galactosyltransferase 1 multiple interactions ISO Mifepristone inhibits the reaction [Progesterone affects the expression of GGTA1 mRNA] CTD PMID:22414680 NCBI chr 3:14,614,099...14,701,185
Ensembl chr 3:14,614,122...14,644,951
JBrowse link
G Ghr growth hormone receptor decreases expression EXP Mifepristone results in decreased expression of GHR mRNA CTD PMID:25972201 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression ISO Mifepristone results in increased expression of GJA1 mRNA CTD PMID:17584828 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gmppa GDP-mannose pyrophosphorylase A decreases expression ISO Mifepristone results in decreased expression of GMPPA mRNA CTD PMID:17584828 NCBI chr 9:82,632,267...82,639,811
Ensembl chr 9:82,632,230...82,639,821
JBrowse link
G Gnpat glyceronephosphate O-acyltransferase multiple interactions ISO Mifepristone inhibits the reaction [Hydrocortisone results in increased expression of GNPAT mRNA] CTD PMID:25763180 NCBI chr19:57,614,813...57,640,524
Ensembl chr19:57,614,628...57,640,726
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO [Mifepristone co-treated with 1-Naphthylisothiocyanate] results in decreased expression of GPT protein CTD PMID:27374722 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Grb10 growth factor receptor bound protein 10 decreases expression EXP Mifepristone results in decreased expression of GRB10 mRNA CTD PMID:25972201 NCBI chr14:92,021,851...92,122,249
Ensembl chr14:92,021,851...92,117,923
JBrowse link
G Grb2 growth factor receptor bound protein 2 multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein promotes the reaction [EGFR protein binds to GRB2 protein]]] CTD PMID:10807665 NCBI chr10:104,193,953...104,263,071
Ensembl chr10:104,193,955...104,263,071
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 decreases expression ISO Mifepristone results in decreased expression of GRIA1 mRNA CTD PMID:17584828 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in increased phosphorylation of GSK3B protein] CTD PMID:16882987 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression ISO Mifepristone results in increased expression of GSTA1 mRNA CTD PMID:17584828 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression
multiple interactions
EXP Mifepristone results in increased expression of GSTA2 mRNA
Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTA2 mRNA]]
CTD PMID:11502894, PMID:17690134 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gstt2 glutathione S-transferase, theta 2 decreases expression ISO Mifepristone results in decreased expression of GSTT2 mRNA CTD PMID:17584828 NCBI chr20:13,760,810...13,764,481
Ensembl chr20:13,760,810...13,764,475
JBrowse link
G Hbegf heparin-binding EGF-like growth factor decreases expression EXP Mifepristone results in decreased expression of HBEGF mRNA CTD PMID:18591650 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hdac2 histone deacetylase 2 increases expression
multiple interactions
ISO
EXP
Mifepristone results in increased expression of HDAC2 mRNA
Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of HDAC2 protein]; Mifepristone inhibits the reaction [Dexamethasone results in increased expression of HDAC2 mRNA]; Mifepristone inhibits the reaction [Dexamethasone results in increased expression of HDAC2 protein]
CTD PMID:17584828, PMID:31518422 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hdac7 histone deacetylase 7 multiple interactions ISO
EXP
Mifepristone inhibits the reaction [Dexamethasone results in increased expression of HDAC7 mRNA]
Mifepristone inhibits the reaction [Corticosterone results in increased expression of HDAC7 mRNA]; Mifepristone inhibits the reaction [Corticosterone results in increased expression of HDAC7 protein]
CTD PMID:29902490, PMID:31306741 NCBI chr 7:139,280,396...139,319,108
Ensembl chr 7:139,281,187...139,318,455
JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of HES1 mRNA] CTD PMID:29222744 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A increases expression ISO Mifepristone results in increased expression of HIGD1A mRNA CTD PMID:17584828 NCBI chr 8:130,482,492...130,491,888
Ensembl chr 8:130,482,493...130,491,998
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO Mifepristone inhibits the reaction [Hydrocortisone results in decreased expression of HMGCR mRNA] CTD PMID:31075344 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
multiple interactions
EXP Mifepristone results in decreased expression of HMOX1 mRNA
[Mifepristone co-treated with Paraquat] results in increased expression of HMOX1 mRNA; NFE2L2 protein promotes the reaction [[Mifepristone co-treated with Paraquat] results in increased expression of HMOX1 mRNA]
CTD PMID:24812154, PMID:25972201 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone results in increased expression of HNF4A mRNA] CTD PMID:19022236 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hoxa10 homeobox A10 multiple interactions ISO Mifepristone inhibits the reaction [Medroxyprogesterone Acetate results in increased expression of HOXA10 mRNA] CTD PMID:21670700 NCBI chr 4:82,285,940...82,295,892
Ensembl chr 4:82,285,528...82,295,470
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase multiple interactions
decreases expression
ISO
EXP
Mifepristone inhibits the reaction [Dexamethasone results in increased expression of and results in increased activity of HPGD protein]
Mifepristone results in decreased expression of HPGD mRNA
CTD PMID:15680906, PMID:17584828, PMID:25972201 NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
JBrowse link
G Hpgds hematopoietic prostaglandin D synthase decreases expression EXP Mifepristone results in decreased expression of HPGDS mRNA CTD PMID:25972201 NCBI chr 4:95,945,356...95,970,666
Ensembl chr 4:95,946,025...95,970,666
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein promotes the reaction [EGFR protein binds to HRAS protein]]] CTD PMID:10807665 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 multiple interactions ISO
EXP
[Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [[HSD11B1 protein results in increased activity of Cortisone] inhibits the reaction [sulforafan results in increased activity of NFE2L2 protein]]; Mifepristone affects the reaction [Hydrocortisone affects the expression of HSD11B1 mRNA]; Mifepristone inhibits the reaction [bisphenol A results in increased expression of HSD11B1 mRNA]
Mifepristone inhibits the reaction [Corticosterone promotes the reaction [[trimethyltin chloride results in increased abundance of trimethyltin] which results in increased expression of HSD11B1 mRNA]]
[Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [HSD11B1 protein results in decreased activity of NFE2L2 protein]
CTD PMID:22606287, PMID:23090578, PMID:30528684, PMID:30993381 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions
increases expression
ISO Masoprocol promotes the reaction [Mifepristone results in increased activity of HSD11B2 protein]; Mifepristone inhibits the reaction [12-Hydroxy-5,8,10,14-eicosatetraenoic Acid results in decreased activity of HSD11B2 protein]; Mifepristone inhibits the reaction [Hydrocortisone results in decreased expression of HSD11B2 mRNA]; Mifepristone inhibits the reaction [Progesterone results in decreased activity of HSD11B2 protein]; Mifepristone inhibits the reaction [Progesterone results in decreased expression of HSD11B2 mRNA]; Mifepristone inhibits the reaction [Progesterone results in decreased expression of HSD11B2 protein]
Mifepristone results in increased expression of HSD11B2 mRNA; Mifepristone results in increased expression of HSD11B2 protein
CTD PMID:18032417, PMID:30528684 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307
JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 decreases expression ISO Mifepristone results in decreased expression of HSD17B6 mRNA CTD PMID:17584828 NCBI chr 7:2,412,370...2,431,249
Ensembl chr 7:2,412,363...2,431,197
Ensembl chr13:2,412,363...2,431,197
JBrowse link
G Hsd17b8 hydroxysteroid (17-beta) dehydrogenase 8 decreases expression ISO Mifepristone results in decreased expression of HSD17B8 mRNA CTD PMID:17584828 NCBI chr20:3,817,212...3,819,316
Ensembl chr20:3,817,179...3,819,235
JBrowse link
G Hsf1 heat shock transcription factor 1 multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone results in decreased activity of HSF1 protein] CTD PMID:14673132 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hspa13 heat shock protein family A (Hsp70) member 13 increases expression ISO Mifepristone results in increased expression of STCH mRNA CTD PMID:17584828 NCBI chr11:14,146,515...14,160,697
Ensembl chr11:14,144,130...14,160,892
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B increases expression ISO Mifepristone results in increased expression of HTR2B mRNA CTD PMID:17584828 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
decreases expression
ISO
EXP
Mifepristone inhibits the reaction [Medroxyprogesterone Acetate inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]]; Mifepristone inhibits the reaction [Progesterone inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]]
Mifepristone results in decreased expression of ICAM1 mRNA
Mifepristone inhibits the reaction [Halothane results in increased expression of ICAM1 mRNA]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [Halothane results in increased expression of ICAM1 mRNA]]
CTD PMID:15358673, PMID:21501669, PMID:22157104, PMID:25972201 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [CD28 protein results in increased secretion of IFNG protein]]; Mifepristone inhibits the reaction [Dydrogesterone results in decreased expression of IFNG protein]; Mifepristone inhibits the reaction [rimexolone inhibits the reaction [CD28 protein results in increased secretion of IFNG protein]]
Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of IFNG protein]
CTD PMID:12504806, PMID:16045524, PMID:20363256 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
decreases expression
ISO
EXP
Mifepristone inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased secretion of IGF1 protein]; Mifepristone inhibits the reaction [Hydrocortisone results in decreased expression of IGF1 mRNA]; Mifepristone inhibits the reaction [Progesterone results in increased secretion of IGF1 protein]
Mifepristone results in decreased expression of IGF1 mRNA
CTD PMID:15809018, PMID:25972201, PMID:30528684 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions ISO Mifepristone affects the reaction [Hydrocortisone affects the expression of IGF1R mRNA] CTD PMID:30528684 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in increased secretion of IGFBP1 protein] CTD PMID:26604029 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression ISO Mifepristone results in increased expression of IGFBP3 mRNA CTD PMID:17584828 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression ISO Mifepristone results in decreased expression of IGFBP5 mRNA CTD PMID:17584828 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Nadolol co-treated with Mifepristone] promotes the reaction [methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]]
[Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in decreased expression of IL10 protein]; [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of IL10 mRNA]
CTD PMID:16321413, PMID:22736252 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12b interleukin 12B multiple interactions ISO [Nadolol co-treated with Mifepristone] inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]
Mifepristone inhibits the reaction [R-1,1,1-trifluoro-4-(5-fluoro-2,3-dihydrobenzofuran-7-yl)-4-methyl-2-(((2-methyl-5-quinolyl)amino)methyl)pentan-2-ol inhibits the reaction [endotoxin, Escherichia coli results in increased secretion of IL12B protein]]
CTD PMID:16321413, PMID:19422381 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 increases expression ISO Mifepristone results in increased expression of IL13RA2 mRNA CTD PMID:17584828 NCBI chr  X:118,443,955...118,514,716
Ensembl chr  X:118,443,823...118,513,061
JBrowse link
G Il17a interleukin 17A multiple interactions ISO Mifepristone inhibits the reaction [Progesterone promotes the reaction [Halothane results in increased expression of IL17A protein]] CTD PMID:21501669 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il18 interleukin 18 multiple interactions ISO [fulvestrant co-treated with Mifepristone] inhibits the reaction [[Progesterone co-treated with Estrogens] inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA]] CTD PMID:17850464 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Mifepristone inhibits the reaction [Hydrocortisone inhibits the reaction [IL1A protein results in increased activity of MMP9 protein]] CTD PMID:18722610 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
[Mifepristone co-treated with Paraquat] results in increased expression of IL1B protein; Mifepristone inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL1B protein]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [IL1B protein results in increased activity of MMP9 protein]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [IL1B protein results in increased expression of MMP9 mRNA]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [IL1B protein results in increased expression of PLAT mRNA]]; Mifepristone promotes the reaction [IL1B protein results in increased expression of SERPINE1 protein]; NFE2L2 protein inhibits the reaction [[Mifepristone co-treated with Paraquat] results in increased expression of IL1B protein]
Mifepristone inhibits the reaction [Fluticasone inhibits the reaction [IL1B protein results in increased expression of SELE mRNA]]
Mifepristone inhibits the reaction [Ethanol results in decreased expression of IL1B mRNA]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [Halothane results in increased expression of IL1B mRNA]]
CTD PMID:7473187, PMID:9371735, PMID:15963473, PMID:21501669, PMID:24812154, PMID:30229846 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [CD28 protein results in increased secretion of IL2 protein]]; Mifepristone inhibits the reaction [rimexolone inhibits the reaction [CD28 protein results in increased secretion of IL2 protein]]
Mifepristone inhibits the reaction [Ethanol results in decreased expression of IL2 mRNA]
CTD PMID:7473187, PMID:20363256 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il4 interleukin 4 multiple interactions ISO Mifepristone inhibits the reaction [Dydrogesterone results in increased expression of IL4 protein]
Mifepristone inhibits the reaction [Ethanol results in decreased expression of IL4 mRNA]
CTD PMID:7473187, PMID:16045524 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of IL5 protein] CTD PMID:12504806 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases secretion
ISO
EXP
[Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of IL6 mRNA]; [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of IL6 protein]; Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of IL6 mRNA]; Mifepristone inhibits the reaction [Dydrogesterone results in increased expression of IL6 protein]
[Mifepristone co-treated with Paraquat] results in increased expression of IL6 protein; Mifepristone inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL6 protein]; NFE2L2 protein inhibits the reaction [[Mifepristone co-treated with Paraquat] results in increased expression of IL6 protein]
Mifepristone inhibits the reaction [ciglitazone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [Halothane results in increased expression of IL6 mRNA]]; Mifepristone inhibits the reaction [rosiglitazone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]
Mifepristone results in decreased secretion of IL6 protein
CTD PMID:15684043, PMID:16045524, PMID:16134523, PMID:21501669, PMID:22736252, PMID:24812154, PMID:30229846, PMID:32619553 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Inhba inhibin subunit beta A increases expression ISO Mifepristone results in increased expression of INHBA mRNA CTD PMID:17584828 NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [Mifepristone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein; Mifepristone inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]; Mifepristone inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein] CTD PMID:29782964 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Insig2 insulin induced gene 2 decreases expression EXP Mifepristone results in decreased expression of INSIG2 mRNA CTD PMID:25972201 NCBI chr13:37,264,818...37,292,718
Ensembl chr13:37,266,312...37,287,458
JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 decreases expression ISO Mifepristone results in decreased expression of IRAK2 protein CTD PMID:17701593 NCBI chr 4:145,594,575...145,651,066
Ensembl chr 4:145,594,575...145,651,053
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 multiple interactions ISO Mifepristone inhibits reaction [Dexamethasone increases Irak3 mRNA in respiratory endothelial cells] RGD PMID:25585690 RGD:11527046 NCBI chr 7:64,922,830...64,982,224
Ensembl chr 7:64,923,615...64,982,281
JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 decreases expression ISO Mifepristone results in decreased expression of IRAK4 protein CTD PMID:17701593 NCBI chr 7:135,803,723...135,831,006
Ensembl chr 7:135,803,698...135,832,652
JBrowse link
G Itga6 integrin subunit alpha 6 increases expression ISO Mifepristone results in increased expression of ITGA6 mRNA CTD PMID:17584828 NCBI chr 3:58,442,904...58,515,124
Ensembl chr 3:58,443,101...58,515,124
JBrowse link
G Itgal integrin subunit alpha L decreases expression EXP Mifepristone results in decreased expression of ITGAL mRNA CTD PMID:25972201 NCBI chr 1:198,744,053...198,781,745
Ensembl chr 1:198,744,050...198,781,750
JBrowse link
G Itgbl1 integrin subunit beta like 1 decreases expression EXP Mifepristone results in decreased expression of ITGBL1 mRNA CTD PMID:25972201 NCBI chr15:110,114,148...110,378,970
Ensembl chr15:110,114,148...110,378,969
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Mifepristone results in increased expression of JUNB mRNA CTD PMID:12605714 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 decreases expression EXP Mifepristone results in decreased expression of KCNMA1 mRNA CTD PMID:25972201 NCBI chr15:344,204...1,048,849
Ensembl chr15:344,360...1,047,956
JBrowse link
G Kdelr2 KDEL endoplasmic reticulum protein retention receptor 2 increases expression ISO Mifepristone results in increased expression of KDELR2 mRNA CTD PMID:17584828 NCBI chr12:13,192,452...13,210,758
Ensembl chr12:13,192,453...13,210,758
JBrowse link
G Kdr kinase insert domain receptor multiple interactions ISO Mifepristone inhibits the reaction [Corticosterone results in decreased expression of KDR protein] CTD PMID:21647420 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Kif27 kinesin family member 27 increases expression ISO Mifepristone results in increased expression of KIF27 mRNA CTD PMID:17584828 NCBI chr17:6,701,287...6,776,599
Ensembl chr17:6,701,315...6,772,349
JBrowse link
G Kiz kizuna centrosomal protein increases expression ISO Mifepristone results in increased expression of KIZ mRNA CTD PMID:17584828 NCBI chr 3:141,067,981...141,173,738
Ensembl chr 3:141,068,023...141,173,858
JBrowse link
G Klf4 Kruppel like factor 4 multiple interactions EXP Mifepristone inhibits the reaction [Corticosterone results in decreased expression of KLF4 mRNA]; Mifepristone inhibits the reaction [Corticosterone results in decreased expression of KLF4 protein] CTD PMID:31306741 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G Klhl6 kelch-like family member 6 increases expression ISO Mifepristone results in increased expression of KLHL6 mRNA CTD PMID:17584828 NCBI chr11:84,745,958...84,785,315
Ensembl chr11:84,745,904...84,785,893
JBrowse link
G Kmt2d lysine methyltransferase 2D decreases expression ISO Mifepristone results in decreased expression of KMT2D mRNA CTD PMID:17584828 NCBI chr 7:140,507,137...140,542,479
Ensembl chr 7:140,489,492...140,546,908
JBrowse link
G Lama2 laminin subunit alpha 2 decreases expression ISO Mifepristone results in decreased expression of LAMA2 mRNA CTD PMID:17584828 NCBI chr 1:18,491,264...19,143,486
Ensembl chr 1:18,491,384...19,143,269
JBrowse link
G Lama3 laminin subunit alpha 3 decreases expression ISO Mifepristone results in decreased expression of LAMA3 mRNA CTD PMID:17584828 NCBI chr18:3,704,866...3,941,215
Ensembl chr18:3,705,916...3,940,838
JBrowse link
G Lama5 laminin subunit alpha 5 decreases expression EXP Mifepristone results in decreased expression of LAMA5 mRNA CTD PMID:25972201 NCBI chr 3:175,553,042...175,601,112
Ensembl chr 3:175,553,045...175,601,127
JBrowse link
G Lamc2 laminin subunit gamma 2 increases expression ISO Mifepristone results in increased expression of LAMC2 mRNA CTD PMID:17584828 NCBI chr13:70,566,643...70,632,126
Ensembl chr13:70,566,643...70,626,252
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of LDLR mRNA]; Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of LDLR protein]; Mifepristone inhibits the reaction [Hydrocortisone results in decreased expression of LDLR mRNA] CTD PMID:31075344, PMID:32234517 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 decreases expression EXP Mifepristone results in decreased expression of LDLRAP1 mRNA CTD PMID:25972201 NCBI chr 5:152,964,294...152,987,286
Ensembl chr 5:152,966,591...152,987,211
JBrowse link
G Ldoc1 LDOC1, regulator of NFKB signaling decreases expression ISO Mifepristone results in decreased expression of LDOC1 mRNA CTD PMID:17584828 NCBI chr  X:144,699,737...144,778,947 JBrowse link
G Lefty1 left right determination factor 1 multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone results in increased expression of LEFTY1 mRNA] CTD PMID:25136773 NCBI chr13:99,212,778...99,217,786
Ensembl chr13:99,214,389...99,217,786
JBrowse link
G Lepr leptin receptor decreases expression EXP Mifepristone results in decreased expression of LEPR mRNA CTD PMID:25972201 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Lgals3 galectin 3 decreases expression EXP Mifepristone results in decreased expression of LGALS3 mRNA CTD PMID:25972201 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
increases secretion
EXP Mifepristone promotes the reaction [[Tetrachlorodibenzodioxin co-treated with Gonadotropins, Equine] results in increased expression of LHB protein]
Mifepristone results in increased secretion of LHB protein
CTD PMID:12606454, PMID:19215433 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 decreases expression ISO Mifepristone results in decreased expression of LMCD1 mRNA CTD PMID:17584828 NCBI chr 4:144,192,989...144,252,554
Ensembl chr 4:144,192,989...144,252,551
JBrowse link
G Lox lysyl oxidase decreases expression EXP Mifepristone results in decreased expression of LOX mRNA CTD PMID:25972201 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Lpar3 lysophosphatidic acid receptor 3 multiple interactions
decreases expression
ISO Mifepristone inhibits the reaction [Progesterone results in increased expression of LPAR3 mRNA]
Mifepristone results in decreased expression of LPAR3 mRNA
CTD PMID:16815476 NCBI chr 2:252,090,634...252,159,221
Ensembl chr 2:252,090,669...252,159,903
JBrowse link
G Lpl lipoprotein lipase decreases expression
increases expression
EXP
ISO
Mifepristone results in decreased expression of LPL mRNA
Mifepristone results in increased expression of LPL protein
CTD PMID:25972201, PMID:26018136 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lum lumican increases expression ISO Mifepristone results in increased expression of LUM mRNA CTD PMID:17584828 NCBI chr 7:38,820,058...38,826,862
Ensembl chr 7:38,819,771...38,826,862
JBrowse link
G Lxn latexin increases expression ISO Mifepristone results in increased expression of LXN mRNA CTD PMID:17584828 NCBI chr 2:164,628,565...164,634,434
Ensembl chr 2:164,628,566...164,634,434
JBrowse link
G Ly6e lymphocyte antigen 6 family member E multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in decreased expression of LY6E mRNA] CTD PMID:27264040 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 decreases expression EXP Mifepristone results in decreased expression of LYVE1 mRNA CTD PMID:25972201 NCBI chr 1:175,663,266...175,676,699
Ensembl chr 1:175,663,266...175,676,699
JBrowse link
G Maml3 mastermind-like transcriptional coactivator 3 increases expression ISO Mifepristone results in increased expression of MAML3 mRNA CTD PMID:17584828 NCBI chr 2:140,734,138...141,276,886 JBrowse link
G Maoa monoamine oxidase A multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone results in increased expression of MAOA mRNA] CTD PMID:15946989 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Map1b microtubule-associated protein 1B increases expression ISO Mifepristone results in increased expression of MAP1B mRNA CTD PMID:17584828 NCBI chr 2:29,675,391...29,768,750
Ensembl chr 2:29,675,391...29,768,750
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein results in increased phosphorylation of MAP2K1 protein]] CTD PMID:10807665 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP
Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of MAPK1 protein modified form]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [Estradiol results in increased phosphorylation of MAPK1 protein]]
Mifepristone inhibits the reaction [Promegestone results in increased phosphorylation of MAPK1 protein]
Mifepristone results in increased phosphorylation of and results in increased activity of MAPK1 protein
CTD PMID:15358673, PMID:16020483, PMID:16175315, PMID:18097517, PMID:20535544 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO
EXP
Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]]; Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of MAPK3 protein modified form]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [Estradiol results in increased phosphorylation of MAPK3 protein]]
Mifepristone results in increased phosphorylation of and results in increased activity of MAPK3 protein
Mifepristone inhibits the reaction [Promegestone results in increased phosphorylation of MAPK3 protein]
CTD PMID:10807665, PMID:15358673, PMID:16020483, PMID:16175315, PMID:18097517, PMID:20535544 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk6 mitogen-activated protein kinase 6 increases expression ISO Mifepristone results in increased expression of MAPK6 mRNA CTD PMID:17584828 NCBI chr 8:82,328,013...82,351,108
Ensembl chr 8:82,328,020...82,351,108
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein results in increased phosphorylation of MAPK8 protein]] CTD PMID:10807665 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Marcksl1 MARCKS-like 1 increases expression ISO Mifepristone results in increased expression of MARCKSL1 mRNA CTD PMID:17584828 NCBI chr 5:147,714,163...147,716,486
Ensembl chr 5:147,714,163...147,716,485
JBrowse link
G Mcam melanoma cell adhesion molecule decreases expression EXP Mifepristone results in decreased expression of MCAM mRNA CTD PMID:25972201 NCBI chr 8:48,472,824...48,481,005
Ensembl chr 8:48,472,824...48,481,001
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO Mifepristone results in increased expression of MDM2 mRNA CTD PMID:12605714 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mef2c myocyte enhancer factor 2C decreases expression EXP Mifepristone results in decreased expression of MEF2C mRNA CTD PMID:25972201 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
G Meis1 Meis homeobox 1 decreases expression EXP Mifepristone results in decreased expression of MEIS1 mRNA CTD PMID:25972201 NCBI chr14:103,182,178...103,321,809
Ensembl chr14:103,181,281...103,321,270
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase multiple interactions ISO Mifepristone inhibits the reaction [ginsenoside Rg1 results in increased expression of MET protein] CTD PMID:26115870 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mgll monoglyceride lipase decreases expression EXP Mifepristone results in decreased expression of MGLL mRNA CTD PMID:25972201 NCBI chr 4:120,671,436...120,773,458
Ensembl chr 4:120,671,489...120,771,088
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone results in increased expression of MGMT mRNA] CTD PMID:20308330 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mir148a microRNA 148a multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone results in increased expression of MIR148A mRNA] CTD PMID:32234517 NCBI chr 4:81,013,269...81,013,365
Ensembl chr 4:81,013,269...81,013,365
JBrowse link
G Mir23a microRNA 23a multiple interactions ISO Mifepristone inhibits the reaction [ginsenoside Rg1 results in decreased expression of MIR23A mRNA] CTD PMID:26115870 NCBI chr19:25,318,582...25,318,656
Ensembl chr19:25,318,582...25,318,656
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO Mifepristone results in decreased expression of MKI67 protein CTD PMID:18579510 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mmd monocyte to macrophage differentiation-associated increases expression ISO Mifepristone results in increased expression of MMD mRNA CTD PMID:17584828 NCBI chr10:77,687,964...77,783,737
Ensembl chr10:77,755,216...77,783,779
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone results in decreased secretion of MMP1 protein] CTD PMID:15698539 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp10 matrix metallopeptidase 10 increases expression ISO Mifepristone results in increased expression of MMP10 mRNA CTD PMID:17584828 NCBI chr 8:5,734,348...5,742,243
Ensembl chr 8:5,734,348...5,742,243
JBrowse link
G Mmp14 matrix metallopeptidase 14 increases expression ISO Mifepristone results in increased expression of MMP14 mRNA CTD PMID:17584828 NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655
JBrowse link
G Mmp16 matrix metallopeptidase 16 increases expression ISO Mifepristone results in increased expression of MMP16 mRNA CTD PMID:17584828 NCBI chr 5:31,568,344...31,818,368
Ensembl chr 5:31,568,419...31,810,484
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO
EXP
Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [sodium bisulfide results in increased expression of MMP2 mRNA]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [sodium bisulfide results in increased expression of MMP2 protein]]; Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of MMP2 mRNA]; Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of MMP2 protein]
Mifepristone inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of MMP2 protein]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Hydrogen Sulfide results in increased expression of MMP2 mRNA]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Hydrogen Sulfide results in increased expression of MMP2 protein]]
CTD PMID:24722316, PMID:30229846, PMID:32619553 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression
multiple interactions
ISO Mifepristone results in increased expression of MMP3 mRNA
Mifepristone inhibits the reaction [Progesterone results in decreased expression of MMP3 mRNA]
CTD PMID:17584828, PMID:27264040 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp7 matrix metallopeptidase 7 increases expression ISO Mifepristone results in increased expression of MMP7 mRNA CTD PMID:17584828 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP
ISO
Mifepristone inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of MMP9 protein]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Hydrogen Sulfide results in increased expression of MMP9 mRNA]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Hydrogen Sulfide results in increased expression of MMP9 protein]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [IL1B protein results in increased activity of MMP9 protein]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [IL1B protein results in increased expression of MMP9 mRNA]]
Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [sodium bisulfide results in increased expression of MMP9 mRNA]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [sodium bisulfide results in increased expression of MMP9 protein]]; Mifepristone inhibits the reaction [Hydrocortisone inhibits the reaction [IL1A protein results in increased activity of MMP9 protein]]
CTD PMID:15963473, PMID:18722610, PMID:24722316, PMID:30229846 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpzl1 myelin protein zero-like 1 decreases expression ISO Mifepristone results in decreased expression of MPZL1 mRNA CTD PMID:17584828 NCBI chr13:83,805,244...83,842,074
Ensembl chr13:83,805,244...83,842,051
JBrowse link
G Mstn myostatin multiple interactions EXP Mifepristone inhibits the reaction [Dexamethasone results in increased expression of MSTN mRNA]; Mifepristone inhibits the reaction [Dexamethasone results in increased expression of MSTN protein] CTD PMID:12721153 NCBI chr 9:53,310,977...53,315,804
Ensembl chr 9:53,309,598...53,315,915
JBrowse link
G Mta1 metastasis associated 1 decreases expression ISO Mifepristone results in decreased expression of MTA1 mRNA CTD PMID:17584828 NCBI chr 6:137,911,302...137,950,066
Ensembl chr 6:137,924,293...137,950,075
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO Mifepristone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of MTOR protein] CTD PMID:22266097 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Muc1 mucin 1, cell surface associated multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone results in increased expression of MUC1 protein] CTD PMID:9949172 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Mifepristone results in decreased expression of MYC mRNA CTD PMID:12605714, PMID:17584828 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions ISO Mifepristone inhibits the reaction [[Dexamethasone co-treated with Doxorubicin] results in increased expression of MYH7 mRNA]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Verapamil results in decreased expression of MYH7 mRNA]] CTD PMID:19596060 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Myl2 myosin light chain 2 multiple interactions ISO Mifepristone inhibits the reaction [[Dexamethasone co-treated with Doxorubicin] results in increased expression of MYL2 mRNA]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [[Verapamil co-treated with Doxorubicin] results in decreased expression of MYL2 mRNA]] CTD PMID:19596060 NCBI chr12:39,951,863...39,959,065
Ensembl chr12:39,951,987...39,958,239
JBrowse link
G Mylip myosin regulatory light chain interacting protein decreases expression EXP Mifepristone results in decreased expression of MYLIP mRNA CTD PMID:25972201 NCBI chr17:19,682,040...19,703,681
Ensembl chr17:19,682,040...19,703,681
JBrowse link
G Mylk3 myosin light chain kinase 3 multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in decreased expression of MYLK3 mRNA] CTD PMID:27264040 NCBI chr19:27,388,163...27,442,451
Ensembl chr19:27,404,712...27,441,536
JBrowse link
G Myo1e myosin IE decreases expression EXP Mifepristone results in decreased expression of MYO1E mRNA CTD PMID:25972201 NCBI chr 8:76,644,715...76,840,240
Ensembl chr 8:76,754,492...76,839,593
JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase multiple interactions EXP Mifepristone inhibits the reaction [Ozone results in increased expression of NAGLU protein] CTD PMID:29247675 NCBI chr10:88,979,363...88,986,879
Ensembl chr10:88,979,383...88,986,867
JBrowse link
G Ncmap noncompact myelin associated protein multiple interactions ISO Mifepristone promotes the reaction [Progesterone affects the expression of NCMAP mRNA] CTD PMID:22414680 NCBI chr 5:153,729,250...153,737,161
Ensembl chr 5:153,729,250...153,737,161
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO [Mifepristone binds to AR protein] promotes the reaction [NCOA2 protein binds to KLK3 enhancer]; [Mifepristone binds to AR protein] promotes the reaction [NCOA2 protein binds to KLK3 promoter] CTD PMID:15308689 NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 decreases expression EXP Mifepristone results in decreased expression of NCOA3 mRNA CTD PMID:25972201 NCBI chr 3:162,692,176...162,788,582
Ensembl chr 3:162,692,185...162,787,548
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions ISO [Mifepristone binds to AR protein] promotes the reaction [NCOR1 protein binds to KLK3 promoter] CTD PMID:15308689 NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
JBrowse link
G Ndp norrin cystine knot growth factor NDP decreases expression ISO Mifepristone results in decreased expression of NDP mRNA CTD PMID:17584828 NCBI chr  X:6,791,090...6,815,586
Ensembl chr  X:6,791,136...6,815,583
Ensembl chr  X:6,791,136...6,815,583
JBrowse link
G Neurl1 neuralized E3 ubiquitin protein ligase 1 increases expression ISO Mifepristone results in increased expression of NEURL1 mRNA CTD PMID:17584828 NCBI chr 1:266,953,006...267,038,879
Ensembl chr 1:266,952,561...267,038,883
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP
ISO
[Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [HSD11B1 protein results in decreased activity of NFE2L2 protein]; [Mifepristone co-treated with Paraquat] results in increased expression of NFE2L2 mRNA; NFE2L2 protein inhibits the reaction [[Mifepristone co-treated with Paraquat] results in decreased activity of CAT protein]; NFE2L2 protein inhibits the reaction [[Mifepristone co-treated with Paraquat] results in increased expression of IL1B protein]; NFE2L2 protein inhibits the reaction [[Mifepristone co-treated with Paraquat] results in increased expression of IL6 protein]; NFE2L2 protein inhibits the reaction [[Mifepristone co-treated with Paraquat] results in increased expression of RELA protein]; NFE2L2 protein inhibits the reaction [[Mifepristone co-treated with Paraquat] results in increased expression of TNF protein]; NFE2L2 protein promotes the reaction [[Mifepristone co-treated with Paraquat] results in increased expression of HMOX1 mRNA]; NFE2L2 protein promotes the reaction [[Mifepristone co-treated with Paraquat] results in increased expression of NQO1 mRNA]
[Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [[HSD11B1 protein results in increased activity of Cortisone] inhibits the reaction [sulforafan results in increased activity of NFE2L2 protein]]; [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in decreased activity of CAT protein]; [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in decreased expression of IL10 protein]; [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of CASP3 mRNA]; [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of CASP9 mRNA]; [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of CYCS mRNA]; [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of IL10 mRNA]; [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of IL6 mRNA]; [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of IL6 protein]; [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of TNF protein]
CTD PMID:22606287, PMID:22736252, PMID:24812154 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Mifepristone inhibits the reaction [Progesterone inhibits the reaction [[Estradiol co-treated with TNF protein] results in increased activity of NFKB1 protein]] CTD PMID:15866594 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Mifepristone inhibits the reaction [[Dexamethasone co-treated with CD28 protein] results in increased expression of NFKBIA mRNA]; Mifepristone inhibits the reaction [[rimexolone co-treated with CD28 protein] results in increased expression of NFKBIA mRNA]; Mifepristone inhibits the reaction [Hydrocortisone results in increased expression of NFKBIA mRNA] CTD PMID:20363256, PMID:25763180 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in increased expression of NME2 mRNA] CTD PMID:15674352 NCBI chr10:81,648,216...81,653,717
Ensembl chr10:81,648,216...81,653,717
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP
Mifepristone inhibits the reaction [Progesterone results in increased expression of NOS2 mRNA]; Mifepristone inhibits the reaction [Progesterone results in increased expression of NOS2 protein]
Mifepristone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]
CTD PMID:10231168, PMID:18710710 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
decreases expression
ISO Mifepristone inhibits the reaction [ginsenoside Re results in increased phosphorylation of NOS3 protein]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [Estradiol results in increased activity of NOS3 protein]]; Mifepristone inhibits the reaction [Progesterone results in increased expression of and results in increased phosphorylation of NOS3 protein]; Mifepristone inhibits the reaction [Progesterone results in increased expression of NOS3 mRNA]; Mifepristone inhibits the reaction [Progesterone results in increased expression of NOS3 protein]
Mifepristone results in decreased expression of NOS3 protein
CTD PMID:15358673, PMID:17490654, PMID:18710710 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Notch4 notch receptor 4 decreases expression EXP Mifepristone results in decreased expression of NOTCH4 mRNA CTD PMID:25972201 NCBI chr20:4,329,794...4,353,868
Ensembl chr20:4,329,811...4,353,785
JBrowse link
G Nova1 NOVA alternative splicing regulator 1 increases expression ISO Mifepristone results in increased expression of NOVA1 mRNA CTD PMID:17584828 NCBI chr 6:66,960,126...67,085,836
Ensembl chr 6:66,963,510...67,085,390
JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin multiple interactions EXP Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of NPHS2 mRNA] CTD PMID:30359671 NCBI chr13:73,929,136...73,941,522
Ensembl chr13:73,929,136...73,941,522
JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP
ISO
Mifepristone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NPPA mRNA]
Mifepristone inhibits the reaction [[Dexamethasone co-treated with Doxorubicin] results in increased expression of NPPA mRNA]
CTD PMID:16533503, PMID:19596060 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions
ISO
EXP
Mifepristone results in decreased expression of NQO1 mRNA
[Mifepristone co-treated with Paraquat] results in increased expression of NQO1 mRNA; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [benz(a)anthracene results in increased activity of NQO1 protein]]; Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]]; NFE2L2 protein promotes the reaction [[Mifepristone co-treated with Paraquat] results in increased expression of NQO1 mRNA]
CTD PMID:7587946, PMID:17584828, PMID:17690134, PMID:24812154 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
increases expression
ISO
EXP
[Mifepristone results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA; [Mifepristone results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; Mifepristone binds to and results in increased activity of NR1I2 protein; NR1I2 protein promotes the reaction [Mifepristone results in increased expression of CYP3A4 mRNA]
Mifepristone results in increased expression of NR1I2 mRNA
Mifepristone inhibits the reaction [Dexamethasone results in increased expression of NR1I2 mRNA]
CTD PMID:12235278, PMID:14570758, PMID:15456840, PMID:16054614, PMID:17041008, PMID:20599767, PMID:26187274 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
increases expression
ISO [Mifepristone results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; Mifepristone inhibits the reaction [Dexamethasone results in increased expression of NR1I3 mRNA]
Mifepristone results in increased expression of NR1I3 mRNA
CTD PMID:16608920, PMID:17041008 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions
increases expression
increases activity
affects binding
decreases expression
ISO
EXP
[Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [[HSD11B1 protein results in increased activity of Cortisone] inhibits the reaction [sulforafan results in increased activity of NFE2L2 protein]]; [Mifepristone binds to and results in decreased activity of NR3C1 protein] which results in decreased susceptibility to Dexamethasone; Mifepristone analog binds to and results in decreased activity of NR3C1 protein; Mifepristone binds to and results in decreased activity of NR3C1 protein; Mifepristone inhibits the reaction [Dexamethasone binds to and results in increased activity of NR3C1 protein]; Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of NR3C1 mRNA]; Mifepristone inhibits the reaction [Dexamethasone results in increased activity of NR3C1 protein]; Mifepristone inhibits the reaction [Hydrocortisone affects the localization of NR3C1 protein]; Mifepristone inhibits the reaction [Hydrocortisone results in increased activity of NR3C1 protein]; Mifepristone inhibits the reaction [NR3C1 protein promotes the reaction [Dexamethasone results in increased expression of CYP3A4 mRNA]]; Mifepristone inhibits the reaction [teriflunomide results in increased activity of NR3C1 protein]
Mifepristone results in increased expression of NR3C1 mRNA
Mifepristone results in increased activity of NR3C1 protein
NR3C1 protein binds to Mifepristone
Mifepristone results in decreased expression of NR3C1 mRNA; Mifepristone results in decreased expression of NR3C1 protein
[Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [Corticosterone results in increased expression of PTGS2 mRNA]; [Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [Corticosterone results in increased expression of PTGS2 protein]; [Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [HSD11B1 protein results in decreased activity of NFE2L2 protein]; [Mifepristone binds to and results in decreased activity of NR3C1 protein] which results in decreased susceptibility to Morphine; Mifepristone binds to and results in decreased activity of NR3C1 protein; Mifepristone inhibits the reaction [Corticosterone promotes the reaction [NR3C1 protein binds to PTGS2 promoter]]; Mifepristone inhibits the reaction [Dexamethasone affects the localization of NR3C1 protein]; Mifepristone promotes the reaction [CEBPB protein binds to NR3C1 protein]
Mifepristone binds to and results in decreased activity of NR3C1 protein; Mifepristone binds to and results in increased activity of NR3C1 protein; Mifepristone inhibits the reaction [Corticosterone results in decreased expression of NR3C1 protein]; Mifepristone inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein]
Mifepristone binds to NR3C1 protein
CTD PMID:1597467, PMID:9371735, PMID:10219967, PMID:11502894, PMID:15014116, PMID:15249158, PMID:15705660, PMID:15829718, PMID:15946989, PMID:16019588, PMID:16608920, PMID:16806946, PMID:17509631, PMID:18272184, PMID:18556366, PMID:18650268, PMID:18722610, PMID:19022236, PMID:19672399, PMID:21647420, PMID:22039522, PMID:22140582, PMID:22606287, PMID:24091107, PMID:24418828, PMID:25056680, PMID:25110054, PMID:26647222, PMID:26778350, PMID:29777833, PMID:30364229, PMID:30528684, PMID:30582956 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Ntn4 netrin 4 increases expression ISO Mifepristone results in increased expression of NTN4 mRNA CTD PMID:17584828 NCBI chr 7:34,533,543...34,649,330
Ensembl chr 7:34,533,543...34,649,481
JBrowse link
G Nubp2 nucleotide binding protein 2 increases expression ISO Mifepristone results in increased expression of NUBP2 mRNA CTD PMID:17584828 NCBI chr10:14,244,201...14,247,930
Ensembl chr10:14,244,203...14,247,886
JBrowse link
G Olah oleoyl-ACP hydrolase decreases expression EXP Mifepristone results in decreased expression of OLAH mRNA CTD PMID:25972201 NCBI chr17:78,878,673...78,903,919
Ensembl chr17:78,879,058...78,903,967
JBrowse link
G Ostm1 osteoclastogenesis associated transmembrane protein 1 increases expression ISO Mifepristone results in increased expression of OSTM1 mRNA CTD PMID:17584828 NCBI chr20:47,394,979...47,430,304
Ensembl chr20:47,395,014...47,430,284
JBrowse link
G P2rx3 purinergic receptor P2X 3 multiple interactions EXP Mifepristone inhibits the reaction [Progesterone results in decreased activity of P2RX3 protein] CTD PMID:21178388 NCBI chr 3:72,403,992...72,447,801
Ensembl chr 3:72,403,993...72,447,801
JBrowse link
G P2ry14 purinergic receptor P2Y14 increases expression ISO Mifepristone results in increased expression of P2RY14 mRNA CTD PMID:17584828 NCBI chr 2:149,331,948...149,379,336
Ensembl chr 2:149,331,948...149,347,796
JBrowse link
G Pam peptidylglycine alpha-amidating monooxygenase decreases expression EXP Mifepristone results in decreased expression of PAM mRNA CTD PMID:25972201 NCBI chr 9:111,028,543...111,177,588
Ensembl chr 9:111,028,575...111,177,602
JBrowse link
G Pamr1 peptidase domain containing associated with muscle regeneration 1 decreases expression EXP Mifepristone results in decreased expression of PAMR1 mRNA CTD PMID:25972201 NCBI chr 3:92,403,533...92,502,094
Ensembl chr 3:92,403,582...92,502,089
JBrowse link
G Paqr7 progestin and adipoQ receptor family member 7 decreases expression ISO Mifepristone results in decreased expression of PAQR7 mRNA CTD PMID:17584828 NCBI chr 5:152,708,782...152,720,230
Ensembl chr 5:152,708,775...152,720,229
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO Mifepristone inhibits the reaction [Dexamethasone results in increased cleavage of PARP1 protein]
Mifepristone results in increased cleavage of PARP1 protein
CTD PMID:16525653, PMID:16644695 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pc pyruvate carboxylase decreases expression ISO
EXP
Mifepristone results in decreased expression of PC mRNA CTD PMID:17584828, PMID:25972201 NCBI chr 1:219,759,157...219,859,854
Ensembl chr 1:219,759,183...219,859,848
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO
EXP
Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Clofibrate results in increased expression of PCK1 mRNA]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [rosiglitazone results in increased expression of PCK1 mRNA]]
Mifepristone inhibits the reaction [Hydrocortisone results in increased expression of PCK1 mRNA]
CTD PMID:9518257, PMID:26647222 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pde2a phosphodiesterase 2A multiple interactions ISO
EXP
Mifepristone inhibits the reaction [Corticosterone results in increased expression of PDE2A protein] CTD PMID:22850435 NCBI chr 1:166,534,643...166,626,158
Ensembl chr 1:166,534,643...166,626,158
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha decreases expression EXP Mifepristone results in decreased expression of PDGFRA mRNA CTD PMID:25972201 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta decreases expression EXP Mifepristone results in decreased expression of PDGFRB mRNA CTD PMID:25972201 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase decreases expression ISO Mifepristone results in decreased expression of PEMT mRNA CTD PMID:17584828 NCBI chr10:46,339,821...46,404,640
Ensembl chr10:46,339,821...46,404,642
JBrowse link
G Per1 period circadian regulator 1 multiple interactions EXP
ISO
Mifepristone inhibits the reaction [Progesterone results in increased expression of PER1 mRNA] CTD PMID:17761890, PMID:20096720 NCBI chr10:55,681,761...55,696,557
Ensembl chr10:55,687,050...55,695,994
JBrowse link
G Pf4 platelet factor 4 decreases expression EXP Mifepristone results in decreased expression of PF4 mRNA CTD PMID:25972201 NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258
JBrowse link
G Pgr progesterone receptor multiple interactions
decreases expression
decreases activity
affects activity
ISO
EXP
Mifepristone analog binds to and results in decreased activity of PGR protein; Mifepristone binds to and results in decreased activity of PGR protein; Mifepristone inhibits the reaction [16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased activity of PGR protein]; Mifepristone inhibits the reaction [[Progestins results in increased activity of PGR protein] which results in increased expression of VEGFA]; Mifepristone inhibits the reaction [methoxyacetic acid promotes the reaction [Promegestone results in increased activity of PGR protein]]; Mifepristone inhibits the reaction [Progesterone results in increased expression of PGR protein]; Mifepristone promotes the reaction [Progesterone affects the expression of PGR mRNA]
Mifepristone results in decreased expression of PGR protein
[Mifepristone binds to and results in decreased activity of PGR protein] which results in decreased susceptibility to Progesterone; [Mifepristone binds to and results in decreased activity of PGR protein] which results in increased expression of CCL2 mRNA; [Mifepristone binds to and results in decreased activity of PGR protein] which results in increased expression of CCL2 protein; Mifepristone binds to and results in decreased activity of PGR protein; Mifepristone inhibits the reaction [Progesterone results in increased expression of PGR mRNA]
Mifepristone results in decreased activity of PGR protein
Mifepristone affects the activity of PGR protein
CTD PMID:1544902, PMID:10888668, PMID:15103026, PMID:15509668, PMID:15811074, PMID:15845615, PMID:15870863, PMID:15925510, PMID:16601080, PMID:16806946, PMID:18262749, PMID:18606702, PMID:19215433, PMID:19570671, PMID:20726854, PMID:22266097, PMID:22414680, PMID:25752796, PMID:26022396, PMID:27264040 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 decreases expression ISO Mifepristone results in decreased expression of PIBF1 mRNA; Mifepristone results in decreased expression of PIBF1 protein CTD PMID:17701593 NCBI chr15:83,494,110...83,663,202
Ensembl chr15:83,495,377...83,663,143
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase multiple interactions ISO Mifepristone promotes the reaction [Progesterone affects the expression of PIM1 mRNA] CTD PMID:22414680 NCBI chr20:8,165,423...8,169,557
Ensembl chr20:8,165,307...8,169,555
JBrowse link
G Pitrm1 pitrilysin metallopeptidase 1 decreases expression EXP Mifepristone results in decreased expression of PITRM1 mRNA CTD PMID:25972201 NCBI chr17:68,477,423...68,509,113
Ensembl chr17:68,477,446...68,509,120
JBrowse link
G Pkp2 plakophilin 2 decreases expression EXP Mifepristone results in decreased expression of PKP2 mRNA CTD PMID:25972201 NCBI chr11:88,912,163...88,972,213 JBrowse link
G Plat plasminogen activator, tissue type increases expression
decreases expression
multiple interactions
ISO
EXP
Mifepristone results in increased expression of PLAT mRNA
Mifepristone results in decreased expression of PLAT mRNA
Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [IL1B protein results in increased expression of PLAT mRNA]]
CTD PMID:15963473, PMID:17584828, PMID:25972201 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plb1 phospholipase B1 decreases expression EXP Mifepristone results in decreased expression of PLB1 mRNA CTD PMID:25972201 NCBI chr 6:25,375,699...25,507,108
Ensembl chr 6:25,397,537...25,507,073
JBrowse link
G Plcl1 phospholipase C-like 1 decreases expression EXP Mifepristone results in decreased expression of PLCL1 mRNA CTD PMID:25972201 NCBI chr 9:62,016,112...62,349,244
Ensembl chr 9:62,291,405...62,349,309
JBrowse link
G Pld1 phospholipase D1 increases expression ISO Mifepristone results in increased expression of PLD1 mRNA CTD PMID:17584828 NCBI chr 2:113,651,967...113,849,403
Ensembl chr 2:113,652,348...113,849,403
JBrowse link
G Pln phospholamban multiple interactions EXP Mifepristone inhibits the reaction [Progesterone inhibits the reaction [bisphenol A results in increased phosphorylation of PLN protein]]; Mifepristone inhibits the reaction [progesterone-11-bovine serum albumin inhibits the reaction [bisphenol A results in increased phosphorylation of PLN protein]] CTD PMID:28324061 NCBI chr20:34,633,157...34,642,904
Ensembl chr20:34,633,157...34,642,904
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 increases expression ISO Mifepristone results in increased expression of PLOD2 mRNA CTD PMID:17584828 NCBI chr 8:99,977,334...100,059,736
Ensembl chr 8:99,977,334...100,059,736
JBrowse link
G Plxdc2 plexin domain containing 2 increases expression ISO Mifepristone results in increased expression of PLXDC2 mRNA CTD PMID:17584828 NCBI chr17:83,221,795...83,619,291
Ensembl chr17:83,221,827...83,610,272
JBrowse link
G Podxl podocalyxin-like decreases expression EXP Mifepristone results in decreased expression of PODXL mRNA CTD PMID:25972201 NCBI chr 4:58,829,049...58,893,353
Ensembl chr 4:58,829,060...58,893,170
JBrowse link
G Pold2 DNA polymerase delta 2, accessory subunit decreases expression ISO Mifepristone results in decreased expression of POLD2 mRNA CTD PMID:17584828 NCBI chr14:86,111,416...86,117,578
Ensembl chr14:86,111,294...86,117,578
JBrowse link
G Pomc proopiomelanocortin multiple interactions EXP Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of POMC mRNA] CTD PMID:32445661 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
decreases expression
ISO
EXP
Mifepristone inhibits the reaction [bisphenol A results in increased expression of PPARG mRNA]; Mifepristone inhibits the reaction [butylparaben results in increased expression of PPARG mRNA]
Mifepristone inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of PPARG protein]
Mifepristone results in decreased expression of PPARG mRNA
CTD PMID:22956630, PMID:25972201, PMID:27145005, PMID:30229846 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppp1r1c protein phosphatase 1, regulatory (inhibitor) subunit 1C increases expression ISO Mifepristone results in increased expression of PPP1R1C mRNA CTD PMID:17584828 NCBI chr 3:66,673,060...66,783,501
Ensembl chr 3:66,673,071...66,780,075
JBrowse link
G Ppp2r3a protein phosphatase 2, regulatory subunit B'', alpha increases expression ISO Mifepristone results in increased expression of PPP2R3A mRNA CTD PMID:17584828 NCBI chr 8:109,481,352...109,621,462
Ensembl chr 8:109,482,614...109,621,408
JBrowse link
G Ppt2 palmitoyl-protein thioesterase 2 increases expression ISO Mifepristone results in increased expression of PPT2 mRNA CTD PMID:17584828 NCBI chr20:4,381,455...4,401,638
Ensembl chr20:4,381,455...4,401,610
JBrowse link
G Prkca protein kinase C, alpha multiple interactions ISO Mifepristone binds to and results in decreased activity of PRKCA protein CTD PMID:16581232 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Prl prolactin multiple interactions
increases expression
ISO
EXP
Mifepristone inhibits the reaction [Medroxyprogesterone Acetate results in increased expression of PRL mRNA]
Mifepristone results in increased expression of PRL mRNA; Mifepristone results in increased expression of PRL protein
Mifepristone promotes the reaction [estradiol 3-benzoate results in increased secretion of PRL protein]
CTD PMID:2159045, PMID:15774544, PMID:17584828, PMID:18832805 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Prodh1 proline dehydrogenase 1 decreases expression ISO Mifepristone results in decreased expression of PRODH mRNA CTD PMID:17584828 NCBI chr11:87,058,478...87,075,785
Ensembl chr11:87,058,616...87,075,785
JBrowse link
G Prpsap1 phosphoribosyl pyrophosphate synthetase-associated protein 1 multiple interactions EXP Mifepristone inhibits the reaction [Progesterone results in increased expression of PRPSAP1 mRNA] CTD PMID:10888668 NCBI chr10:105,430,516...105,492,154
Ensembl chr10:105,430,520...105,452,228
JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 increases expression ISO Mifepristone results in increased expression of PSMC6 mRNA CTD PMID:17584828 NCBI chr15:19,667,453...19,688,916
Ensembl chr15:19,667,453...19,688,914
JBrowse link
G Ptbp2 polypyrimidine tract binding protein 2 increases expression ISO Mifepristone results in increased expression of PTBP2 mRNA CTD PMID:17584828 NCBI chr 2:223,261,444...223,323,075
Ensembl chr 2:223,262,852...223,322,585
JBrowse link
G Ptgds prostaglandin D2 synthase decreases expression ISO Mifepristone results in decreased expression of PTGDS mRNA CTD PMID:17584828 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
JBrowse link
G Ptger1 prostaglandin E receptor 1 multiple interactions EXP Mifepristone results in increased expression of and affects the localization of PTGER1 protein CTD PMID:19801535 NCBI chr19:24,799,422...24,803,373
Ensembl chr19:24,800,072...24,803,373
JBrowse link
G Ptger2 prostaglandin E receptor 2 increases expression EXP Mifepristone results in increased expression of PTGER2 mRNA; Mifepristone results in increased expression of PTGER2 protein CTD PMID:19801535 NCBI chr15:19,336,029...19,349,759
Ensembl chr15:19,338,175...19,350,210
JBrowse link
G Ptger3 prostaglandin E receptor 3 multiple interactions EXP Mifepristone results in increased expression of and affects the localization of PTGER3 protein CTD PMID:19801535 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
JBrowse link
G Ptger4 prostaglandin E receptor 4 increases expression EXP Mifepristone results in increased expression of PTGER4 mRNA; Mifepristone results in increased expression of PTGER4 protein CTD PMID:19801535 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
JBrowse link
G Ptgir prostaglandin I2 receptor increases expression ISO Mifepristone results in increased expression of PTGIR mRNA CTD PMID:17584828 NCBI chr 1:78,833,449...78,835,832
Ensembl chr 1:78,833,157...78,837,623
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO
EXP
Mifepristone results in decreased expression of PTGS1 mRNA CTD PMID:17584828, PMID:25972201 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [Corticosterone results in increased expression of PTGS2 mRNA]; [Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [Corticosterone results in increased expression of PTGS2 protein]; Mifepristone inhibits the reaction [Corticosterone promotes the reaction [NR3C1 protein binds to PTGS2 promoter]]; Mifepristone inhibits the reaction [Dexamethasone results in increased expression of PTGS2 protein]; Mifepristone inhibits the reaction [Hydrocortisone results in increased expression of PTGS2 protein] CTD PMID:18650268 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptprk protein tyrosine phosphatase, receptor type, K increases expression ISO Mifepristone results in increased expression of PTPRK mRNA CTD PMID:17584828 NCBI chr 1:17,445,052...18,058,266
Ensembl chr 1:17,446,417...18,058,055
JBrowse link
G Pxdn peroxidasin decreases expression EXP Mifepristone results in decreased expression of PXDN mRNA CTD PMID:25972201 NCBI chr 6:48,866,496...48,982,368
Ensembl chr 6:48,866,601...48,980,340
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions ISO Mifepristone inhibits the reaction [Hydrocortisone results in increased expression of RAP1A mRNA] CTD PMID:25763180 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
JBrowse link
G Rap1b RAP1B, member of RAS oncogene family increases expression
multiple interactions
ISO
EXP
Mifepristone results in increased expression of RAP1B mRNA
Mifepristone inhibits the reaction [Progesterone results in increased expression of RAP1B mRNA]
CTD PMID:10888668, PMID:17584828 NCBI chr 7:60,850,406...60,878,226
Ensembl chr 7:60,853,930...60,860,990
JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 multiple interactions ISO Mifepristone inhibits the reaction [Hydrocortisone results in increased expression of RAPGEF3 mRNA] CTD PMID:25763180 NCBI chr 7:139,232,263...139,254,668
Ensembl chr 7:139,232,251...139,254,551
JBrowse link
G Rarg retinoic acid receptor, gamma decreases expression ISO Mifepristone results in decreased expression of RARG mRNA CTD PMID:17584828 NCBI chr 7:143,840,739...143,863,206
Ensembl chr 7:143,839,980...143,863,186
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 multiple interactions ISO Mifepristone promotes the reaction [Progesterone affects the expression of RASGRP1 mRNA] CTD PMID:22414680 NCBI chr 3:108,984,029...109,044,420
Ensembl chr 3:108,984,029...109,044,420
JBrowse link
G Rb1 RB transcriptional corepressor 1 increases activity ISO Mifepristone results in increased activity of RB1 protein CTD PMID:15297425 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 increases expression ISO Mifepristone results in increased expression of RB1CC1 mRNA CTD PMID:17584828 NCBI chr 5:13,033,918...13,097,369
Ensembl chr 5:13,033,918...13,097,341
JBrowse link
G Rbp4 retinol binding protein 4 multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in decreased expression of RBP4 mRNA] CTD PMID:27264040 NCBI chr 1:256,806,476...256,813,678
Ensembl chr 1:256,806,472...256,813,711
JBrowse link
G Reep2 receptor accessory protein 2 decreases expression ISO Mifepristone results in decreased expression of REEP2 mRNA CTD PMID:17584828 NCBI chr18:27,632,562...27,641,594
Ensembl chr18:27,632,786...27,641,591
JBrowse link
G Reep6 receptor accessory protein 6 decreases expression ISO Mifepristone results in decreased expression of REEP6 mRNA CTD PMID:17584828 NCBI chr 7:12,240,059...12,246,814
Ensembl chr 7:12,240,060...12,246,729
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
Mifepristone inhibits the reaction [Dexamethasone results in decreased phosphorylation of and affects the localization of RELA protein]; Mifepristone inhibits the reaction [Medroxyprogesterone Acetate inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]]
[Mifepristone co-treated with Paraquat] results in increased expression of RELA protein; NFE2L2 protein inhibits the reaction [[Mifepristone co-treated with Paraquat] results in increased expression of RELA protein]
CTD PMID:15358673, PMID:24812154, PMID:32619553 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ret ret proto-oncogene multiple interactions EXP Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of RET mRNA] CTD PMID:30359671 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
JBrowse link
G Rhob ras homolog family member B decreases expression EXP Mifepristone results in decreased expression of RHOB mRNA CTD PMID:25972201 NCBI chr 6:33,689,127...33,691,301
Ensembl chr 6:33,689,127...33,691,301
JBrowse link
G Rhog ras homolog family member G decreases expression ISO Mifepristone results in decreased expression of RHOG mRNA CTD PMID:17584828 NCBI chr 1:167,336,147...167,347,720
Ensembl chr 1:167,335,248...167,347,671
JBrowse link
G Rnf146 ring finger protein 146 increases expression ISO Mifepristone results in increased expression of RNF146 mRNA CTD PMID:17584828 NCBI chr 1:30,856,923...30,873,814
Ensembl chr 1:30,863,217...30,873,808
JBrowse link
G Rpl39 ribosomal protein L39 increases expression ISO Mifepristone results in increased expression of RPL39 mRNA CTD PMID:17584828 NCBI chr  X:123,705,241...123,707,257
Ensembl chr  X:123,705,235...123,708,211
JBrowse link
G Rprm reprimo, TP53 dependent G2 arrest mediator homolog decreases expression ISO Mifepristone results in decreased expression of RPRM mRNA CTD PMID:17584828 NCBI chr 3:39,595,301...39,596,718
Ensembl chr 3:39,595,301...39,596,718
JBrowse link
G Rps10 ribosomal protein S10 increases expression ISO Mifepristone results in increased expression of RPS10 mRNA CTD PMID:17584828 NCBI chr20:7,215,762...7,220,331
Ensembl chr20:7,215,774...7,219,548
JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 decreases expression EXP Mifepristone results in decreased expression of RPS6KA5 mRNA CTD PMID:25972201 NCBI chr 6:124,557,892...124,735,787
Ensembl chr 6:124,557,913...124,735,778
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 multiple interactions ISO 7-hydroxystaurosporine promotes the reaction [Mifepristone inhibits the reaction [Progesterone results in increased expression of RRM2 protein]]; Mifepristone inhibits the reaction [Progesterone results in increased expression of RRM2 mRNA]; Mifepristone inhibits the reaction [Progesterone results in increased expression of RRM2 protein] CTD PMID:22403396 NCBI chr 6:43,884,627...43,890,818
Ensembl chr 6:43,884,678...43,889,515
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in increased expression of HLA-F mRNA] CTD PMID:22490650 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
G RT1-DOb RT1 class II, locus DOb decreases expression ISO Mifepristone results in decreased expression of HLA-DOB mRNA CTD PMID:17584828 NCBI chr20:4,020,273...4,026,398
Ensembl chr20:4,020,317...4,026,346
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in increased expression of HLA-E mRNA] CTD PMID:22490650 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G Runx2 RUNX family transcription factor 2 decreases expression EXP Mifepristone results in decreased expression of RUNX2 mRNA CTD PMID:20197312 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Rxfp1 relaxin family peptide receptor 1 decreases expression EXP Mifepristone results in decreased expression of RXFP1 mRNA; Mifepristone results in decreased expression of RXFP1 protein CTD PMID:20686183 NCBI chr 2:178,402,411...178,520,213
Ensembl chr 2:178,399,274...178,521,038
JBrowse link
G Ryr2 ryanodine receptor 2 multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in decreased expression of RYR2 mRNA] CTD PMID:27264040 NCBI chr17:65,533,998...65,955,606
Ensembl chr17:65,535,403...65,955,606
JBrowse link
G S100a6 S100 calcium binding protein A6 decreases expression ISO Mifepristone results in decreased expression of S100A6 mRNA CTD PMID:17584828 NCBI chr 2:190,007,013...190,008,512
Ensembl chr 2:190,007,216...190,008,511
JBrowse link
G S100g S100 calcium binding protein G multiple interactions ISO
EXP
Mifepristone inhibits the reaction [bisphenol A results in increased expression of S100G mRNA]; Mifepristone inhibits the reaction [bisphenol A results in increased expression of S100G protein]; Mifepristone inhibits the reaction [Estradiol results in increased expression of S100G mRNA]; Mifepristone inhibits the reaction [nonylphenol results in increased expression of S100G mRNA]; Mifepristone inhibits the reaction [nonylphenol results in increased expression of S100G protein]; Mifepristone inhibits the reaction [octylphenol results in increased expression of S100G mRNA]; Mifepristone inhibits the reaction [octylphenol results in increased expression of S100G protein]; Mifepristone inhibits the reaction [Progesterone results in decreased expression of S100G mRNA]
Mifepristone inhibits the reaction [Triclosan results in increased expression of S100G mRNA]; Mifepristone inhibits the reaction [Triclosan results in increased expression of S100G protein]
CTD PMID:15509668, PMID:22062131, PMID:27264040 NCBI chr  X:33,442,820...33,445,714
Ensembl chr  X:33,443,186...33,445,709
JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions ISO Mifepristone inhibits the reaction [Hydrocortisone results in decreased expression of SCARB1 mRNA] CTD PMID:31075344 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Sec23ip SEC23 interacting protein increases expression ISO Mifepristone results in increased expression of SEC23IP mRNA CTD PMID:17584828 NCBI chr 1:200,167,075...200,210,362
Ensembl chr 1:200,167,169...200,210,377
JBrowse link
G Sec62 SEC62 homolog, preprotein translocation factor increases expression ISO Mifepristone results in increased expression of SEC62 mRNA CTD PMID:17584828 NCBI chr 2:116,188,736...116,225,510
Ensembl chr 2:116,189,862...116,219,750
JBrowse link
G Sele selectin E multiple interactions ISO Mifepristone inhibits the reaction [Fluticasone inhibits the reaction [IL1B protein results in increased expression of SELE mRNA]] CTD PMID:9371735 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Sema3b semaphorin 3B multiple interactions
increases response to substance
ISO Mifepristone inhibits the reaction [Calcitriol results in increased expression of SEMA3B protein]; Mifepristone inhibits the reaction [Progesterone results in increased expression of SEMA3B protein]
SEMA3B protein results in increased susceptibility to Mifepristone
CTD PMID:21933904 NCBI chr 8:116,353,791...116,362,655
Ensembl chr 8:116,354,073...116,361,343
JBrowse link
G Sema3f semaphorin 3F multiple interactions
increases response to substance
ISO Mifepristone inhibits the reaction [Calcitriol results in increased expression of SEMA3F protein]; Mifepristone inhibits the reaction [Progesterone results in increased expression of SEMA3F protein]
SEMA3F protein results in increased susceptibility to Mifepristone
CTD PMID:21933904 NCBI chr 8:116,439,996...116,469,915
Ensembl chr 8:116,437,696...116,469,915
JBrowse link
G Senp1 SUMO specific peptidase 1 increases expression ISO Mifepristone results in increased expression of SENP1 mRNA CTD PMID:17584828 NCBI chr 7:139,626,444...139,684,587
Ensembl chr 7:139,630,515...139,675,245
JBrowse link
G Senp5 SUMO specific peptidase 5 decreases expression EXP Mifepristone results in decreased expression of SENP5 mRNA CTD PMID:25972201 NCBI chr11:72,883,892...72,918,759
Ensembl chr11:72,892,448...72,915,230
JBrowse link
G Septin4 septin 4 decreases expression ISO Mifepristone results in decreased expression of SEPTIN4 mRNA CTD PMID:17584828 NCBI chr10:74,860,068...74,884,196
Ensembl chr10:74,861,714...74,884,196
JBrowse link
G Serf2 small EDRK-rich factor 2 increases expression ISO Mifepristone results in increased expression of SERF2 mRNA CTD PMID:17584828 NCBI chr 3:113,415,757...113,419,417
Ensembl chr 3:113,415,774...113,417,478
JBrowse link
G Serinc5 serine incorporator 5 decreases expression EXP Mifepristone results in decreased expression of SERINC5 mRNA CTD PMID:25972201 NCBI chr 2:22,195,507...22,310,289
Ensembl chr 2:22,195,600...22,310,312
JBrowse link
G Serpine1 serpin family E member 1 decreases expression
multiple interactions
ISO
EXP
Mifepristone results in decreased expression of SERPINE1 mRNA
Mifepristone promotes the reaction [IL1B protein results in increased expression of SERPINE1 protein]
CTD PMID:15963473, PMID:17584828, PMID:25972201 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serpine2 serpin family E member 2 decreases expression EXP Mifepristone results in decreased expression of SERPINE2 mRNA CTD PMID:25972201 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
JBrowse link
G Serpinf1 serpin family F member 1 decreases expression ISO
EXP
Mifepristone results in decreased expression of SERPINF1 mRNA CTD PMID:17584828, PMID:25972201 NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287
JBrowse link
G Sesn3 sestrin 3 increases expression ISO Mifepristone results in increased expression of SESN3 mRNA CTD PMID:17584828 NCBI chr 8:12,823,060...12,878,749
Ensembl chr 8:12,823,155...12,872,705
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 increases expression ISO Mifepristone results in increased expression of SFRP1 mRNA CTD PMID:17584828 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Sgip1 SH3GL interacting endocytic adaptor 1 increases expression ISO Mifepristone results in increased expression of SGIP1 mRNA CTD PMID:17584828 NCBI chr 5:122,300,415...122,498,478
Ensembl chr 5:122,390,522...122,491,203
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 multiple interactions ISO
EXP
Mifepristone inhibits the reaction [Dexamethasone results in increased expression of SGK1 mRNA] CTD PMID:15793248, PMID:17690134, PMID:29222744 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
JBrowse link
G Slc22a3 solute carrier family 22 member 3 decreases expression ISO Mifepristone results in decreased expression of SLC22A3 mRNA CTD PMID:17584828 NCBI chr 1:48,433,079...48,521,261
Ensembl chr 1:48,433,079...48,521,256
JBrowse link
G Slc27a5 solute carrier family 27 member 5 decreases expression ISO Mifepristone results in decreased expression of SLC27A5 mRNA CTD PMID:17584828 NCBI chr 1:65,576,599...65,587,192
Ensembl chr 1:65,576,535...65,587,186
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in increased expression of SLC2A1 protein] CTD PMID:18948400 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc2a5 solute carrier family 2 member 5 multiple interactions EXP Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Fructose results in increased activity of SLC2A5 protein]]; Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Fructose results in increased expression of SLC2A5 mRNA]] CTD PMID:18556366 NCBI chr 5:167,142,182...167,174,203
Ensembl chr 5:167,141,875...167,174,310
JBrowse link
G Slc30a2 solute carrier family 30 member 2 multiple interactions EXP Mifepristone inhibits the reaction [Dexamethasone results in increased expression of SLC30A2 mRNA] CTD PMID:20133611 NCBI chr 5:152,559,577...152,571,800
Ensembl chr 5:152,559,577...152,571,799
JBrowse link
G Slc43a1 solute carrier family 43 member 1 decreases expression ISO Mifepristone results in decreased expression of SLC43A1 mRNA CTD PMID:17584828 NCBI chr 3:72,238,796...72,265,023
Ensembl chr 3:72,238,981...72,264,466
JBrowse link
G Slc7a4 solute carrier family 7, member 4 decreases expression ISO Mifepristone results in decreased expression of SLC7A4 mRNA CTD PMID:17584828 NCBI chr11:87,445,585...87,450,008
Ensembl chr11:87,446,382...87,449,940
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 increases expression ISO Mifepristone results in increased expression of SLCO1A4 mRNA CTD PMID:15456840 NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163
JBrowse link
G Slco2a1 solute carrier organic anion transporter family, member 2a1 multiple interactions ISO Mifepristone promotes the reaction [Progesterone affects the expression of SLCO2A1 mRNA] CTD PMID:22414680 NCBI chr 8:111,495,443...111,577,320
Ensembl chr 8:111,495,331...111,577,833
JBrowse link
G Slit2 slit guidance ligand 2 decreases expression EXP Mifepristone results in decreased expression of SLIT2 mRNA CTD PMID:25972201 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link
G Slit3 slit guidance ligand 3 decreases expression ISO Mifepristone results in decreased expression of SLIT3 mRNA CTD PMID:17584828 NCBI chr10:19,924,200...20,517,918
Ensembl chr10:20,320,878...20,518,518
JBrowse link
G Smurf2 SMAD specific E3 ubiquitin protein ligase 2 increases expression ISO Mifepristone results in increased expression of SMURF2 mRNA CTD PMID:17584828 NCBI chr10:95,018,050...95,118,107
Ensembl chr10:95,018,059...95,062,987
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of SNAI1 protein] CTD PMID:32619553 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snx12 sorting nexin 12 decreases expression ISO Mifepristone results in decreased expression of SNX12 mRNA CTD PMID:17584828 NCBI chr  X:70,989,822...71,127,330
Ensembl chr  X:70,989,822...71,127,278
JBrowse link
G Snx2 sorting nexin 2 increases expression ISO Mifepristone results in increased expression of SNX2 mRNA CTD PMID:17584828 NCBI chr18:48,132,386...48,173,974
Ensembl chr18:48,132,414...48,173,971
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
EXP
ISO
Dexamethasone inhibits the reaction [Mifepristone results in increased expression of SOD2 mRNA]; Mifepristone inhibits the reaction [Progesterone results in decreased expression of SOD2 mRNA]
[Mifepristone co-treated with TNF protein] results in increased expression of SOD2 mRNA; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]]
CTD PMID:9038369, PMID:16195479 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions EXP Mifepristone inhibits the reaction [Progesterone results in decreased expression of SOD3 mRNA] CTD PMID:16195479 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Sox17 SRY-box transcription factor 17 decreases expression EXP Mifepristone results in decreased expression of SOX17 mRNA CTD PMID:25972201 NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907
JBrowse link
G Sox9 SRY-box transcription factor 9 increases expression ISO Mifepristone results in increased expression of SOX9 mRNA CTD PMID:17584828 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Spag1 sperm associated antigen 1 increases expression ISO Mifepristone results in increased expression of SPAG1 mRNA CTD PMID:17584828 NCBI chr 7:74,994,379...75,054,294
Ensembl chr 7:74,994,605...75,054,293
JBrowse link
G Sphk1 sphingosine kinase 1 multiple interactions EXP Mifepristone inhibits the reaction [Progesterone results in increased expression of SPHK1 mRNA] CTD PMID:17164439 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
JBrowse link
G Spon1 spondin 1 decreases expression EXP Mifepristone results in decreased expression of SPON1 mRNA CTD PMID:25972201 NCBI chr 1:178,568,777...178,935,715
Ensembl chr 1:178,636,544...178,935,051
JBrowse link
G Srpx sushi-repeat-containing protein, X-linked decreases expression ISO Mifepristone results in decreased expression of SRPX mRNA CTD PMID:17584828 NCBI chr  X:14,146,618...14,220,756
Ensembl chr  X:14,150,038...14,220,662
JBrowse link
G Srpx2 sushi-repeat-containing protein, X-linked 2 increases expression
decreases expression
ISO
EXP
Mifepristone results in increased expression of SRPX2 mRNA
Mifepristone results in decreased expression of SRPX2 mRNA
CTD PMID:17584828, PMID:25972201 NCBI chr  X:104,734,035...104,760,658
Ensembl chr  X:104,734,082...104,760,547
JBrowse link
G St6galnac2 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 increases expression ISO Mifepristone results in increased expression of ST6GALNAC2 mRNA CTD PMID:17584828 NCBI chr10:105,650,866...105,668,579
Ensembl chr10:105,650,862...105,668,593
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression
multiple interactions
ISO Mifepristone results in decreased expression of STAR mRNA
Mifepristone inhibits the reaction [Hydrocortisone results in decreased expression of STAR mRNA]
Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of STAR mRNA]
CTD PMID:17584828, PMID:29902490, PMID:30528684 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Stmn2 stathmin 2 increases expression ISO Mifepristone results in increased expression of STMN2 mRNA CTD PMID:17584828 NCBI chr 2:95,424,251...95,471,900
Ensembl chr 2:95,424,251...95,472,115
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions EXP Mifepristone inhibits the reaction [Dexamethasone results in increased expression of SULT1A1 mRNA] CTD PMID:9566755 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in increased expression of SULT1E1 mRNA]; Mifepristone inhibits the reaction [Progesterone results in increased expression of SULT1E1 protein] CTD PMID:22414680 NCBI chr14:22,070,861...22,089,264
Ensembl chr14:22,072,024...22,089,248
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 increases expression ISO Mifepristone results in increased expression of SUMO1 protein CTD PMID:14500579 NCBI chr 9:66,453,428...66,483,614
Ensembl chr 9:66,453,438...66,483,614
JBrowse link
G Svep1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 decreases expression EXP Mifepristone results in decreased expression of SVEP1 mRNA CTD PMID:25972201 NCBI chr 5:75,147,245...75,320,873
Ensembl chr 5:75,143,867...75,319,765
JBrowse link
G Svil supervillin increases expression ISO Mifepristone results in increased expression of SVIL mRNA CTD PMID:17584828 NCBI chr17:55,230,298...55,425,967
Ensembl chr17:55,230,298...55,346,279
JBrowse link
G Syngr1 synaptogyrin 1 decreases expression ISO Mifepristone results in decreased expression of SYNGR1 mRNA CTD PMID:17584828 NCBI chr 7:121,311,008...121,334,437
Ensembl chr 7:121,311,024...121,334,437
JBrowse link
G Tat tyrosine aminotransferase multiple interactions ISO
EXP
Mifepristone inhibits the reaction [Dexamethasone results in increased expression of TAT mRNA]
Mifepristone inhibits the reaction [Dexamethasone results in increased activity of TAT protein]; Mifepristone inhibits the reaction [Dexamethasone results in increased expression of TAT mRNA]; Mifepristone inhibits the reaction [Hydrocortisone results in increased expression of TAT mRNA]
CTD PMID:9566755, PMID:15698539, PMID:19022236, PMID:20599767, PMID:26647222, PMID:29222744 NCBI chr19:41,675,639...41,686,195
Ensembl chr19:41,675,355...41,686,229
JBrowse link
G Tcf21 transcription factor 21 decreases expression EXP Mifepristone results in decreased expression of TCF21 mRNA CTD PMID:25972201 NCBI chr 1:23,906,717...23,909,576
Ensembl chr 1:23,906,717...23,909,566
JBrowse link
G Tek TEK receptor tyrosine kinase increases expression ISO Mifepristone results in increased expression of TEK mRNA CTD PMID:17584828 NCBI chr 5:113,725,717...113,852,799
Ensembl chr 5:113,725,717...113,852,799
JBrowse link
G Testin testin gene decreases expression EXP Mifepristone results in decreased expression of TESTIN mRNA CTD PMID:25972201 NCBI chr17:4,194,796...4,225,376
Ensembl chr17:4,212,890...4,225,376
JBrowse link
G Tgfa transforming growth factor alpha decreases expression EXP Mifepristone results in decreased expression of TGFA mRNA CTD PMID:18591650 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
G Tgfb2 transforming growth factor, beta 2 decreases expression EXP Mifepristone results in decreased expression of TGFB2 mRNA CTD PMID:25972201 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 multiple interactions EXP Mifepristone inhibits the reaction [Corticosterone results in decreased expression of TGFBR1 mRNA] CTD PMID:32663519 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Th tyrosine hydroxylase decreases expression
multiple interactions
ISO
EXP
Mifepristone results in decreased expression of TH mRNA
Mifepristone inhibits the reaction [Monocrotophos results in increased activity of TH protein]
CTD PMID:17584828, PMID:22305719 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO Mifepristone results in increased expression of THBS1 mRNA CTD PMID:17584828 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Thra thyroid hormone receptor alpha decreases expression
multiple interactions
ISO Mifepristone results in decreased expression of THRA mRNA
Mifepristone binds to and results in decreased activity of THRA protein
CTD PMID:17584828, PMID:25752796 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
G Thrb thyroid hormone receptor beta increases expression ISO Mifepristone results in increased expression of THRB mRNA CTD PMID:17584828 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
G Timm17a translocase of inner mitochondrial membrane 17A increases expression ISO Mifepristone results in increased expression of TIMM17A mRNA CTD PMID:17584828 NCBI chr13:52,124,641...52,136,127
Ensembl chr13:52,124,635...52,136,127
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP Mifepristone inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of TIMP1 protein] CTD PMID:30229846 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase decreases expression ISO Mifepristone results in decreased expression of TIPARP mRNA CTD PMID:17584828 NCBI chr 2:157,316,293...157,342,979
Ensembl chr 2:157,316,266...157,341,469
JBrowse link
G Tjp1 tight junction protein 1 increases expression ISO Mifepristone results in increased expression of TJP1 mRNA CTD PMID:17584828 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tlr7 toll-like receptor 7 decreases expression ISO Mifepristone results in decreased expression of TLR7 protein CTD PMID:17701593 NCBI chr  X:28,486,836...28,513,004
Ensembl chr  X:28,486,869...28,512,957
JBrowse link
G Tnc tenascin C decreases expression EXP Mifepristone results in decreased expression of TNC mRNA CTD PMID:25972201 NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671
JBrowse link
G Tnf tumor necrosis factor multiple interactions
affects response to substance
ISO
EXP
[Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of TNF protein]; [Mifepristone co-treated with TNF protein] results in increased expression of SOD2 mRNA; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [CD28 protein results in increased secretion of TNF protein]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]]; Mifepristone inhibits the reaction [Dydrogesterone results in decreased expression of TNF protein]; Mifepristone inhibits the reaction [Progesterone inhibits the reaction [[Estradiol co-treated with TNF protein] results in increased activity of NFKB1 protein]]; Mifepristone inhibits the reaction [Progesterone inhibits the reaction [[Estradiol co-treated with TNF protein] results in increased expression of CXCL8 mRNA]]; Mifepristone inhibits the reaction [rimexolone inhibits the reaction [CD28 protein results in increased secretion of TNF protein]]
[Mifepristone co-treated with Paraquat] results in increased expression of TNF protein; Mifepristone inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of TNF protein]; NFE2L2 protein inhibits the reaction [[Mifepristone co-treated with Paraquat] results in increased expression of TNF protein]
TNF protein affects the susceptibility to Mifepristone
Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of TNF protein]; Mifepristone inhibits the reaction [Halothane results in increased expression of TNF mRNA]; Mifepristone inhibits the reaction [Progesterone promotes the reaction [Halothane results in increased expression of TNF mRNA]]
CTD PMID:9038369, PMID:12504806, PMID:12843254, PMID:15866594, PMID:16045524, PMID:20363256, PMID:21501669, PMID:22157104, PMID:22736252, PMID:24812154, PMID:30229846 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B multiple interactions EXP Mifepristone inhibits the reaction [CORT protein results in increased expression of TNFRSF11B mRNA]; Mifepristone inhibits the reaction [Corticosterone results in increased expression of TNFRSF11B mRNA] CTD PMID:27338645, PMID:29981921 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression ISO Mifepristone results in increased expression of TNFRSF1A mRNA CTD PMID:17584828 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [TNFSF10 protein results in increased activity of CASP3 protein]]; Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [TNFSF10 protein results in increased activity of CASP8 protein]] CTD PMID:17070682 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions EXP Mifepristone inhibits the reaction [Corticosterone results in decreased expression of TNFSF11 mRNA] CTD PMID:29981921 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Tp53 tumor protein p53 decreases expression ISO Mifepristone results in decreased expression of TRP53 mRNA CTD PMID:12605714 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trex1 three prime repair exonuclease 1 multiple interactions EXP Mifepristone inhibits the reaction [Amphetamine results in increased expression of TREX1 mRNA] CTD PMID:20298760 NCBI chr 8:117,796,127...117,797,427
Ensembl chr 8:117,796,128...117,797,427
JBrowse link
G Trib2 tribbles pseudokinase 2 increases expression ISO Mifepristone results in increased expression of TRIB2 mRNA CTD PMID:17584828 NCBI chr 6:41,016,722...41,040,972
Ensembl chr 6:41,016,730...41,039,437
JBrowse link
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 multiple interactions ISO Mifepristone inhibits the reaction [Progesterone results in decreased expression of TRPV2 mRNA]; Mifepristone inhibits the reaction [Progesterone results in decreased expression of TRPV2 protein] CTD PMID:27264040 NCBI chr10:48,903,540...48,925,036
Ensembl chr10:48,903,540...48,925,030
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 increases expression ISO Mifepristone results in increased expression of TSC22D1 mRNA CTD PMID:17584828 NCBI chr15:58,554,358...58,658,156
Ensembl chr15:58,554,374...58,658,153
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO Mifepristone inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:25763180, PMID:26647222 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Tspan5 tetraspanin 5 decreases expression EXP Mifepristone results in decreased expression of TSPAN5 mRNA CTD PMID:25972201 NCBI chr 2:244,058,186...244,224,059
Ensembl chr 2:244,058,186...244,224,058
JBrowse link
G Tspo translocator protein decreases expression EXP Mifepristone results in decreased expression of TSPO mRNA CTD PMID:25972201 NCBI chr 7:124,460,358...124,470,610
Ensembl chr 7:124,460,358...124,470,609
JBrowse link
G Txlna taxilin alpha decreases expression ISO Mifepristone results in decreased expression of TXLNA mRNA CTD PMID:17584828 NCBI chr 5:147,830,514...147,846,193
Ensembl chr 5:147,832,469...147,846,095
JBrowse link
G Uqcrb ubiquinol-cytochrome c reductase binding protein increases expression ISO Mifepristone results in increased expression of UQCRB mRNA CTD PMID:17584828 NCBI chr 7:71,264,501...71,269,869
Ensembl chr 7:71,264,514...71,269,869
Ensembl chr 1:71,264,514...71,269,869
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions
decreases expression
ISO
EXP
Mifepristone inhibits the reaction [Medroxyprogesterone Acetate inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 protein]]; Mifepristone inhibits the reaction [Progesterone inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 protein]]
Mifepristone results in decreased expression of VCAM1 mRNA
CTD PMID:15358673, PMID:25972201 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vcl vinculin decreases expression EXP Mifepristone results in decreased expression of VCL mRNA CTD PMID:25972201 NCBI chr15:3,455,211...3,544,738
Ensembl chr15:3,455,211...3,544,702
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
decreases expression
affects expression
ISO
EXP
Mifepristone inhibits the reaction [[Progestins results in increased activity of PGR protein] which results in increased expression of VEGFA]; Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of VEGFA mRNA]; Mifepristone inhibits the reaction [Medroxyprogesterone Acetate results in increased expression of VEGFA mRNA]; Mifepristone inhibits the reaction [Progestins results in increased expression of VEGFA mRNA]
Mifepristone results in decreased expression of VEGFA mRNA
Mifepristone affects the expression of VEGFA mRNA
Mifepristone results in decreased expression of VEGFA protein
CTD PMID:15845615, PMID:15860260, PMID:16638347, PMID:20686183, PMID:25972201, PMID:32619553 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vim vimentin multiple interactions ISO Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of VIM mRNA]; Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of VIM protein] CTD PMID:32619553 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Vldlr very low density lipoprotein receptor decreases expression EXP Mifepristone results in decreased expression of VLDLR mRNA CTD PMID:25972201 NCBI chr 1:245,236,819...245,273,688
Ensembl chr 1:245,237,736...245,269,205
JBrowse link
G Vwf von Willebrand factor multiple interactions ISO Mifepristone inhibits the reaction [Hydrocortisone results in increased expression of VWF mRNA] CTD PMID:25763180 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
JBrowse link
G Wnt5a Wnt family member 5A increases expression ISO Mifepristone results in increased expression of WNT5A mRNA CTD PMID:17584828 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
G Zfp36 zinc finger protein 36 multiple interactions ISO Mifepristone inhibits the reaction [RU24858 inhibits the reaction [Lipopolysaccharides results in increased expression of ZFP36 mRNA]] CTD PMID:15710351 NCBI chr 1:85,380,088...85,382,565
Ensembl chr 1:85,380,088...85,382,569
JBrowse link
G Zfp422 zinc finger protein 422 increases expression ISO Mifepristone results in increased expression of ZNF22 mRNA CTD PMID:17584828 NCBI chr 4:148,757,362...148,761,594
Ensembl chr 4:148,757,363...148,761,547
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    chemical entity 19785
      group 19696
        organic group 18493
          3-oxo-Delta(4)-steroid group 7934
            3-oxo-Delta(4) steroid 7934
              mifepristone 532
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      ketone 16140
                                        oxo steroid 9275
                                          3-oxo steroid 8805
                                            3-oxo-Delta(4) steroid 7934
                                              mifepristone 532
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.