Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:mercaptopurine
go back to main search page
Accession:CHEBI:50667 term browser browse the term
Definition:A member of the class of purines that is 6,7-dihydro-1H-purine carrying a thione group at position 6. An adenine analogue, it is used in the treatment of acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn's disease, and ulcerative colitis.
Synonyms:exact_synonym: 1,7-dihydro-6H-purine-6-thione
 related_synonym: 6-MP;   6-Mercaptopurine;   6-Thiohypoxanthine;   6-Thioxopurine;   Formula=C5H4N4S;   InChI=1S/C5H4N4S/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10);   InChIKey=GLVAUDGFNGKCSF-UHFFFAOYSA-N;   Mercaptopurina;   Mercapurin;   Puri-Nethol;   Purinethol;   SMILES=S=c1[nH]cnc2nc[nH]c12;   mercaptopurinum
 xref: Beilstein:132916;   CAS:50-44-2;   DrugBank:DB01033;   KEGG:C02380;   KEGG:D04931
 xref_mesh: MESH:D015122
 xref: PDBeChem:PM6;   PMID:16267626;   PMID:28011186;   PMID:28166217;   PMID:28212467;   PMID:28295989;   PMID:28301625;   PMID:28406092;   PMID:28418010;   PMID:28484608;   PMID:28574837;   Patent:US2697709;   Patent:US2721866;   Reaxys:132916
 cyclic_relationship: is_tautomer_of CHEBI:2208


show annotations for term's descendants           Sort by:
 
mercaptopurine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 decreases expression EXP Mercaptopurine results in decreased expression of ABCC8 mRNA CTD PMID:23358152 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Acer2 alkaline ceramidase 2 increases expression EXP Mercaptopurine results in increased expression of ACER2 mRNA CTD PMID:23358152 NCBI chr 5:105,230,540...105,279,732
Ensembl chr 5:105,230,580...105,279,731
JBrowse link
G Acod1 aconitate decarboxylase 1 increases expression EXP Mercaptopurine results in increased expression of ACOD1 mRNA CTD PMID:23358152 NCBI chr15:93,612,968...93,622,322
Ensembl chr15:93,612,971...93,622,358
JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression EXP Mercaptopurine results in decreased expression of ACTG2 mRNA CTD PMID:23358152 NCBI chr 4:115,215,160...115,239,746
Ensembl chr 4:115,215,060...115,239,723
JBrowse link
G Actrt3 actin-related protein T3 increases expression EXP Mercaptopurine results in increased expression of ACTRT3 mRNA CTD PMID:23358152 NCBI chr 2:116,416,561...116,418,521
Ensembl chr 2:116,416,507...116,418,582
JBrowse link
G Adm adrenomedullin increases expression EXP Mercaptopurine results in increased expression of ADM mRNA CTD PMID:23358152 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Agt angiotensinogen decreases expression EXP Mercaptopurine results in decreased expression of AGT mRNA CTD PMID:23358152 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase increases expression EXP Mercaptopurine results in increased expression of AGXT mRNA CTD PMID:23358152 NCBI chr 9:100,281,339...100,291,292
Ensembl chr 9:100,281,339...100,291,291
JBrowse link
G Akap12 A-kinase anchoring protein 12 decreases expression EXP Mercaptopurine results in decreased expression of AKAP12 mRNA CTD PMID:23358152 NCBI chr 1:40,816,130...40,906,582
Ensembl chr 1:40,816,107...40,906,581
JBrowse link
G Akap3 A-kinase anchoring protein 3 increases expression EXP Mercaptopurine results in increased expression of AKAP3 mRNA CTD PMID:23358152 NCBI chr 4:159,399,686...159,425,512
Ensembl chr 4:159,403,501...159,425,629
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 decreases expression EXP Mercaptopurine results in decreased expression of ALDH1B1 mRNA CTD PMID:23358152 NCBI chr 5:61,382,351...61,387,359
Ensembl chr 5:61,382,351...61,387,358
JBrowse link
G Alox15 arachidonate 15-lipoxygenase decreases expression EXP Mercaptopurine results in decreased expression of ALOX15 mRNA CTD PMID:23358152 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Alpi alkaline phosphatase, intestinal decreases expression EXP Mercaptopurine results in decreased expression of ALPI mRNA CTD PMID:23358152 NCBI chr 9:94,197,616...94,201,910
Ensembl chr 9:94,197,618...94,201,084
JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 increases expression EXP Mercaptopurine results in increased expression of AMPD3 mRNA CTD PMID:23358152 NCBI chr 1:175,585,301...175,630,479
Ensembl chr 1:175,586,097...175,630,467
JBrowse link
G Angpt2 angiopoietin 2 increases expression EXP Mercaptopurine results in increased expression of ANGPT2 mRNA CTD PMID:23358152 NCBI chr16:75,966,480...76,016,147
Ensembl chr16:75,966,352...76,016,195
JBrowse link
G Anxa9 annexin A9 decreases expression EXP Mercaptopurine results in decreased expression of ANXA9 mRNA CTD PMID:23358152 NCBI chr 2:196,470,318...196,481,568
Ensembl chr 2:196,470,858...196,479,770
JBrowse link
G Apoc3 apolipoprotein C3 decreases expression EXP Mercaptopurine results in decreased expression of APOC3 mRNA CTD PMID:23358152 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Art3 ADP-ribosyltransferase 3 increases expression EXP Mercaptopurine results in increased expression of ART3 mRNA CTD PMID:23358152 NCBI chr14:17,143,037...17,225,389
Ensembl chr14:17,143,040...17,225,389
JBrowse link
G Asb14 ankyrin repeat and SOCS box-containing 14 increases expression EXP Mercaptopurine results in increased expression of ASB14 mRNA CTD PMID:23358152 NCBI chr16:2,537,209...2,556,930
Ensembl chr16:2,537,248...2,556,735
JBrowse link
G Asprv1 aspartic peptidase, retroviral-like 1 increases expression EXP Mercaptopurine results in increased expression of ASPRV1 mRNA CTD PMID:23358152 NCBI chr 4:118,431,755...118,433,286
Ensembl chr 4:118,431,755...118,432,775
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 decreases expression EXP Mercaptopurine results in decreased expression of ATP2A3 mRNA CTD PMID:23358152 NCBI chr10:59,528,849...59,560,440
Ensembl chr10:59,529,785...59,560,433
JBrowse link
G Bard1 BRCA1 associated RING domain 1 decreases expression EXP Mercaptopurine results in decreased expression of BARD1 mRNA CTD PMID:23358152 NCBI chr 9:78,297,723...78,368,777
Ensembl chr 9:78,294,834...78,369,031
JBrowse link
G Batf3 basic leucine zipper ATF-like transcription factor 3 decreases expression EXP Mercaptopurine results in decreased expression of BATF3 mRNA CTD PMID:23358152 NCBI chr13:109,713,376...109,726,438
Ensembl chr13:109,713,489...109,724,863
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Mercaptopurine results in increased expression of BAX protein CTD PMID:9058596 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO Mercaptopurine results in decreased expression of BCL2 protein
[Doxorubicin co-treated with Dexamethasone co-treated with Vincristine co-treated with Cytarabine co-treated with Mercaptopurine co-treated with Methotrexate co-treated with Cyclophosphamide co-treated with Enzymes and Coenzymes] results in increased expression of BCL2 protein
CTD PMID:9058596, PMID:21182165 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO Mercaptopurine results in decreased expression of BCL2L1 protein CTD PMID:12697733 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcorl1 BCL6 co-repressor-like 1 decreases expression EXP Mercaptopurine results in decreased expression of BCORL1 mRNA CTD PMID:23358152 NCBI chr  X:135,187,468...135,233,859
Ensembl chr  X:135,187,468...135,233,839
JBrowse link
G Bspry B-box and SPRY domain containing decreases expression EXP Mercaptopurine results in decreased expression of BSPRY mRNA CTD PMID:23358152 NCBI chr 5:78,334,284...78,356,462
Ensembl chr 5:78,334,284...78,356,460
JBrowse link
G Btbd16 BTB domain containing 16 increases expression EXP Mercaptopurine results in increased expression of BTBD16 mRNA CTD PMID:23358152 NCBI chr 1:201,337,370...201,391,246
Ensembl chr 1:201,337,416...201,391,252
JBrowse link
G C1qa complement C1q A chain increases expression EXP Mercaptopurine results in increased expression of C1QA mRNA CTD PMID:23358152 NCBI chr 5:155,261,254...155,264,101
Ensembl chr 5:155,261,250...155,264,143
JBrowse link
G Ca4 carbonic anhydrase 4 decreases expression EXP Mercaptopurine results in decreased expression of CAR4 mRNA CTD PMID:23358152 NCBI chr10:72,272,286...72,281,069
Ensembl chr10:72,272,248...72,281,067
JBrowse link
G Cap2 cyclase associated actin cytoskeleton regulatory protein 2 increases expression EXP Mercaptopurine results in increased expression of CAP2 mRNA CTD PMID:23358152 NCBI chr17:18,441,614...18,592,866
Ensembl chr17:18,442,127...18,592,750
JBrowse link
G Car7 carbonic anhydrase 7 decreases expression EXP Mercaptopurine results in decreased expression of CAR7 mRNA CTD PMID:23358152 NCBI chr19:636,545...645,935
Ensembl chr19:636,545...645,937
JBrowse link
G Casp3 caspase 3 increases expression EXP Mercaptopurine results in increased expression of CASP3 protein CTD PMID:22688000 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression EXP Mercaptopurine results in decreased expression of CCL5 mRNA CTD PMID:23358152 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccne1 cyclin E1 decreases expression EXP Mercaptopurine results in decreased expression of CCNE1 mRNA CTD PMID:23358152 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ccr6 C-C motif chemokine receptor 6 decreases expression EXP Mercaptopurine results in decreased expression of CCR6 mRNA CTD PMID:23358152 NCBI chr 1:53,063,380...53,087,519
Ensembl chr 1:53,065,025...53,087,474
JBrowse link
G Cd19 CD19 molecule decreases expression EXP Mercaptopurine results in decreased expression of CD19 mRNA CTD PMID:23358152 NCBI chr 1:197,815,422...197,822,123
Ensembl chr 1:197,815,413...197,821,936
JBrowse link
G Cd28 Cd28 molecule multiple interactions ISO Mercaptopurine inhibits the reaction [CD28 protein results in increased activity of [NFKB1 protein binds to RELA protein]] CTD PMID:12697733 NCBI chr 9:67,546,408...67,573,858
Ensembl chr 9:67,546,408...67,571,871
JBrowse link
G Cd68 Cd68 molecule increases expression EXP Mercaptopurine results in increased expression of CD68 mRNA CTD PMID:23358152 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Cd79b CD79b molecule decreases expression EXP Mercaptopurine results in decreased expression of CD79B mRNA CTD PMID:23358152 NCBI chr10:94,497,445...94,500,591
Ensembl chr10:94,497,448...94,500,591
JBrowse link
G Cdc25b cell division cycle 25B decreases expression EXP Mercaptopurine results in decreased expression of CDC25B mRNA CTD PMID:23358152 NCBI chr 3:123,731,539...123,741,696
Ensembl chr 3:123,731,539...123,741,339
JBrowse link
G Cdca3 cell division cycle associated 3 decreases expression EXP Mercaptopurine results in decreased expression of CDCA3 mRNA CTD PMID:23358152 NCBI chr 4:157,347,876...157,351,889
Ensembl chr 4:157,348,020...157,351,604
JBrowse link
G Cdca7l cell division cycle associated 7 like decreases expression EXP Mercaptopurine results in decreased expression of CDCA7L mRNA CTD PMID:23358152 NCBI chr 6:145,739,570...145,785,607
Ensembl chr 6:145,740,035...145,785,606
JBrowse link
G Cela1 chymotrypsin like elastase 1 increases expression EXP Mercaptopurine results in increased expression of CELA1 mRNA CTD PMID:23358152 NCBI chr 7:142,305,337...142,318,621
Ensembl chr 7:142,305,338...142,318,620
JBrowse link
G Cenpw centromere protein W decreases expression EXP Mercaptopurine results in decreased expression of CENPW mRNA CTD PMID:23358152 NCBI chr 1:29,915,443...29,920,598
Ensembl chr 1:29,915,443...29,920,598
JBrowse link
G Ces3a carboxylesterase 3a increases expression EXP Mercaptopurine results in increased expression of CES3 mRNA CTD PMID:23358152 NCBI chr19:37,070,705...37,079,411 JBrowse link
G Ces4a carboxylesterase 4A increases expression EXP Mercaptopurine results in increased expression of CES4A mRNA CTD PMID:23358152 NCBI chr19:37,090,018...37,111,448
Ensembl chr19:37,090,056...37,107,872
JBrowse link
G Chrd chordin increases expression EXP Mercaptopurine results in increased expression of CHRD mRNA CTD PMID:23358152 NCBI chr11:83,858,503...83,867,543
Ensembl chr11:83,858,503...83,867,203
JBrowse link
G Chrdl1 chordin-like 1 decreases expression EXP Mercaptopurine results in decreased expression of CHRDL1 mRNA CTD PMID:23358152 NCBI chr  X:114,554,359...114,658,975
Ensembl chr  X:114,554,359...114,658,931
JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit decreases expression EXP Mercaptopurine results in decreased expression of CHRNA2 mRNA CTD PMID:23358152 NCBI chr15:42,808,897...42,825,179
Ensembl chr15:42,808,897...42,825,179
JBrowse link
G Clec14a C-type lectin domain containing 14A decreases expression EXP Mercaptopurine results in decreased expression of CLEC14A mRNA CTD PMID:23358152 NCBI chr 6:79,303,301...79,306,443
Ensembl chr 6:79,303,304...79,306,443
JBrowse link
G Clec4d C-type lectin domain family 4, member D increases expression EXP Mercaptopurine results in increased expression of CLEC4D mRNA CTD PMID:23358152 NCBI chr 4:156,253,084...156,264,766
Ensembl chr 4:156,253,079...156,264,769
JBrowse link
G Clgn calmegin decreases expression EXP Mercaptopurine results in decreased expression of CLGN mRNA CTD PMID:23358152 NCBI chr19:24,545,257...24,578,527
Ensembl chr19:24,545,318...24,576,798
JBrowse link
G Clic2 chloride intracellular channel 2 increases expression EXP Mercaptopurine results in increased expression of CLIC2 mRNA CTD PMID:23358152 NCBI chr20:295,338...310,363
Ensembl chr20:295,250...310,380
JBrowse link
G Cnmd chondromodulin decreases expression EXP Mercaptopurine results in decreased expression of CNMD mRNA CTD PMID:23358152 NCBI chr15:61,923,291...61,947,840
Ensembl chr15:61,923,299...61,947,764
JBrowse link
G Col11a1 collagen type XI alpha 1 chain decreases expression EXP Mercaptopurine results in decreased expression of COL11A1 mRNA CTD PMID:23358152 NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression EXP Mercaptopurine results in decreased expression of COL1A1 mRNA CTD PMID:23358152 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col2a1 collagen type II alpha 1 chain decreases expression EXP Mercaptopurine results in decreased expression of COL2A1 mRNA CTD PMID:23358152 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
JBrowse link
G Corin corin, serine peptidase increases expression EXP Mercaptopurine results in increased expression of CORIN mRNA CTD PMID:23358152 NCBI chr14:38,247,379...38,474,931
Ensembl chr14:38,247,791...38,473,648
JBrowse link
G Coro6 coronin 6 increases expression EXP Mercaptopurine results in increased expression of CORO6 mRNA CTD PMID:23358152 NCBI chr10:62,691,952...62,700,658
Ensembl chr10:62,691,953...62,699,723
JBrowse link
G Cpe carboxypeptidase E increases expression EXP Mercaptopurine results in increased expression of CPE mRNA CTD PMID:23358152 NCBI chr16:26,906,716...27,014,811
Ensembl chr16:26,906,716...27,014,813
JBrowse link
G Ctsk cathepsin K increases expression EXP Mercaptopurine results in increased expression of CTSK mRNA CTD PMID:23358152 NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
JBrowse link
G Ctsql2 cathepsin Q-like 2 increases expression EXP Mercaptopurine results in increased expression of CTSQL2 mRNA CTD PMID:23358152 NCBI chr17:4,062,294...4,068,108
Ensembl chr17:4,063,432...4,068,100
JBrowse link
G Ctxn3 cortexin 3 increases expression EXP Mercaptopurine results in increased expression of CTXN3 mRNA CTD PMID:23358152 NCBI chr18:52,542,577...52,551,806
Ensembl chr18:52,550,739...52,551,805
JBrowse link
G Cubn cubilin decreases expression EXP Mercaptopurine results in decreased expression of CUBN mRNA CTD PMID:23358152 NCBI chr17:80,584,921...80,807,181
Ensembl chr17:80,584,878...80,807,243
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression EXP Mercaptopurine results in increased expression of CXCL2 mRNA CTD PMID:23358152 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression EXP Mercaptopurine results in increased expression of CYP26A1 mRNA CTD PMID:23358152 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases expression EXP Mercaptopurine results in increased expression of CYP2J4 mRNA CTD PMID:23358152 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 increases expression EXP Mercaptopurine results in increased expression of CYP4A3 mRNA CTD PMID:23358152 NCBI chr 5:134,468,666...134,484,851
Ensembl chr 5:134,469,270...134,484,839
JBrowse link
G Dcaf12l1 DDB1 and CUL4 associated factor 12-like 1 decreases expression EXP Mercaptopurine results in decreased expression of DCAF12L1 mRNA CTD PMID:23358152 NCBI chr  X:131,340,045...131,344,038
Ensembl chr  X:131,340,045...131,343,853
JBrowse link
G Def6 DEF6 guanine nucleotide exchange factor increases expression EXP Mercaptopurine results in increased expression of DEF6 mRNA CTD PMID:23358152 NCBI chr20:7,788,120...7,809,011
Ensembl chr20:7,788,084...7,809,560
JBrowse link
G Dhrs9 dehydrogenase/reductase 9 increases expression EXP Mercaptopurine results in increased expression of DHRS9 mRNA CTD PMID:23358152 NCBI chr 3:55,623,671...55,645,883
Ensembl chr 3:55,623,634...55,648,325
JBrowse link
G Dio2 iodothyronine deiodinase 2 increases expression EXP Mercaptopurine results in increased expression of DIO2 mRNA CTD PMID:23358152 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
JBrowse link
G Dkkl1 dickkopf like acrosomal protein 1 decreases expression EXP Mercaptopurine results in decreased expression of DKKL1 mRNA CTD PMID:23358152 NCBI chr 1:101,205,426...101,210,675
Ensembl chr 1:101,205,426...101,210,675
JBrowse link
G Dlk2 delta like non-canonical Notch ligand 2 increases expression EXP Mercaptopurine results in increased expression of DLK2 mRNA CTD PMID:23358152 NCBI chr 9:17,061,187...17,065,600
Ensembl chr 9:17,061,190...17,065,600
JBrowse link
G Dll3 delta like canonical Notch ligand 3 decreases expression EXP Mercaptopurine results in decreased expression of DLL3 mRNA CTD PMID:23358152 NCBI chr 1:85,485,875...85,493,683
Ensembl chr 1:85,485,289...85,493,685
JBrowse link
G Drd4 dopamine receptor D4 increases expression EXP Mercaptopurine results in increased expression of DRD4 mRNA CTD PMID:23358152 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Duox2 dual oxidase 2 increases expression EXP Mercaptopurine results in increased expression of DUOX2 mRNA CTD PMID:23358152 NCBI chr 3:114,218,187...114,237,808
Ensembl chr 3:114,218,193...114,235,933
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 increases expression EXP Mercaptopurine results in increased expression of EFEMP1 mRNA CTD PMID:23358152 NCBI chr14:113,202,382...113,294,993
Ensembl chr14:113,202,419...113,295,014
JBrowse link
G Efna1 ephrin A1 multiple interactions EXP Mercaptopurine promotes the reaction [GW 1929 results in increased expression of EFNA1 mRNA] CTD PMID:27435855 NCBI chr 2:188,588,808...188,596,156
Ensembl chr 2:188,588,796...188,596,222
JBrowse link
G Ehd3 EH-domain containing 3 increases expression EXP Mercaptopurine results in increased expression of EHD3 mRNA CTD PMID:23358152 NCBI chr 6:25,076,012...25,102,457
Ensembl chr 6:25,074,955...25,100,977
JBrowse link
G Elf5 E74 like ETS transcription factor 5 decreases expression EXP Mercaptopurine results in decreased expression of ELF5 mRNA CTD PMID:23358152 NCBI chr 3:93,333,514...93,374,454
Ensembl chr 3:93,351,619...93,371,656
JBrowse link
G Emcn endomucin decreases expression EXP Mercaptopurine results in decreased expression of EMCN mRNA CTD PMID:23358152 NCBI chr 2:242,634,319...242,715,489
Ensembl chr 2:242,634,399...242,714,182
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression EXP Mercaptopurine results in decreased expression of ENPP2 mRNA CTD PMID:23358152 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 decreases expression EXP Mercaptopurine results in decreased expression of EPB41L3 mRNA CTD PMID:23358152 NCBI chr 9:117,314,935...117,666,408
Ensembl chr 9:117,538,009...117,666,410
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression EXP Mercaptopurine results in decreased expression of ERBB2 mRNA CTD PMID:23358152 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Ervfrd-1 endogenous retrovirus group FRD member 1, envelope decreases expression EXP Mercaptopurine results in decreased expression of ERVFRD-1 mRNA CTD PMID:23358152 NCBI chr12:25,161,130...25,168,182
Ensembl chr12:25,161,130...25,168,182
JBrowse link
G Esr1 estrogen receptor 1 increases expression EXP Mercaptopurine results in increased expression of ESR1 mRNA CTD PMID:23358152 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G F13a1 coagulation factor XIII A1 chain increases expression EXP Mercaptopurine results in increased expression of F13A1 mRNA CTD PMID:23358152 NCBI chr17:28,504,650...28,680,015
Ensembl chr17:28,504,623...28,680,362
JBrowse link
G Fam25a family with sequence similarity 25, member A increases expression EXP Mercaptopurine results in increased expression of FAM25A mRNA CTD PMID:23358152 NCBI chr16:10,702,264...10,706,073
Ensembl chr16:10,702,263...10,706,073
JBrowse link
G Fcgr3a Fc fragment of IgG receptor IIIa increases expression EXP Mercaptopurine results in increased expression of FCGR3A mRNA CTD PMID:23358152 NCBI chr13:89,385,775...89,396,047
Ensembl chr13:89,385,859...89,396,051
JBrowse link
G Fcnb ficolin B increases expression EXP Mercaptopurine results in increased expression of FCN1 mRNA CTD PMID:23358152 NCBI chr 3:6,617,816...6,626,193
Ensembl chr 3:6,617,751...6,626,284
JBrowse link
G Ftl1 ferritin light chain 1 increases expression EXP Mercaptopurine results in increased expression of FTL mRNA CTD PMID:27435855 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G G0s2 G0/G1switch 2 increases expression EXP Mercaptopurine results in increased expression of G0S2 mRNA CTD PMID:23358152 NCBI chr13:112,004,140...112,005,052
Ensembl chr13:112,004,140...112,005,052
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects localization ISO Mercaptopurine affects the localization of GAPDH protein CTD PMID:19628630 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gatm glycine amidinotransferase increases expression EXP Mercaptopurine results in increased expression of GATM mRNA CTD PMID:23358152 NCBI chr 3:114,711,570...114,728,155
Ensembl chr 3:114,711,562...114,728,410
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Mercaptopurine results in increased expression of GCLM mRNA CTD PMID:18222062 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gcm1 glial cells missing transcription factor 1 decreases expression EXP Mercaptopurine results in decreased expression of GCM1 mRNA CTD PMID:23358152 NCBI chr 8:85,355,766...85,369,002
Ensembl chr 8:85,355,766...85,369,002
JBrowse link
G Gdf9 growth differentiation factor 9 increases expression EXP Mercaptopurine results in increased expression of GDF9 mRNA CTD PMID:23358152 NCBI chr10:38,782,519...38,793,238
Ensembl chr10:38,788,992...38,792,940
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide decreases expression EXP Mercaptopurine results in decreased expression of GHRL mRNA CTD PMID:23358152 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066
JBrowse link
G Gjb4 gap junction protein, beta 4 increases expression EXP Mercaptopurine results in increased expression of GJB4 mRNA CTD PMID:23358152 NCBI chr 5:145,416,343...145,421,122
Ensembl chr 5:145,416,343...145,418,992
JBrowse link
G Gng8 G protein subunit gamma 8 increases expression EXP Mercaptopurine results in increased expression of GNG8 mRNA CTD PMID:23358152 NCBI chr 1:78,818,360...78,822,224
Ensembl chr 1:78,818,404...78,822,224
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO Mercaptopurine results in increased expression of GPX2 mRNA CTD PMID:18222062 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO Mercaptopurine results in increased expression of GPX3 mRNA CTD PMID:18222062 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist increases expression EXP Mercaptopurine results in increased expression of GREM1 mRNA CTD PMID:23358152 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Grp gastrin releasing peptide increases expression EXP Mercaptopurine results in increased expression of GRP mRNA CTD PMID:23358152 NCBI chr18:61,563,458...61,576,818
Ensembl chr18:61,563,053...61,576,818
JBrowse link
G Grxcr2 glutaredoxin and cysteine rich domain containing 2 increases expression EXP Mercaptopurine results in increased expression of GRXCR2 mRNA CTD PMID:23358152 NCBI chr18:36,308,925...36,334,643
Ensembl chr18:36,308,925...36,322,320
JBrowse link
G Gss glutathione synthetase increases expression ISO Mercaptopurine results in increased expression of GSS mRNA CTD PMID:18222062 NCBI chr 3:151,076,254...151,106,557
Ensembl chr 3:151,076,254...151,106,557
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance ISO GSTM1 gene polymorphism affects the susceptibility to Mercaptopurine CTD PMID:15713801 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Guca2a guanylate cyclase activator 2A increases expression EXP Mercaptopurine results in increased expression of GUCA2A mRNA CTD PMID:23358152 NCBI chr 5:138,685,634...138,687,476
Ensembl chr 5:138,685,624...138,687,816
JBrowse link
G Gzmb granzyme B increases expression EXP Mercaptopurine results in increased expression of GZMB mRNA CTD PMID:23358152 NCBI chr15:35,413,862...35,417,293
Ensembl chr15:35,413,793...35,417,316
JBrowse link
G Gzmbl1 Granszyme B-like 1 increases expression EXP Mercaptopurine results in increased expression of GZMBL1 mRNA CTD PMID:23358152 NCBI chr  X:123,015,024...123,023,509
Ensembl chr  X:123,015,480...123,018,444
JBrowse link
G Hamp hepcidin antimicrobial peptide increases expression EXP Mercaptopurine results in increased expression of HAMP mRNA CTD PMID:23358152 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 increases expression EXP Mercaptopurine results in increased expression of HAND2 mRNA CTD PMID:23358152 NCBI chr16:36,371,489...36,373,551
Ensembl chr16:36,371,489...36,373,546
JBrowse link
G Hbb hemoglobin subunit beta decreases expression EXP Mercaptopurine results in decreased expression of HBB mRNA; Mercaptopurine results in decreased expression of HBB-B1 mRNA CTD PMID:23358152 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hbe2 hemoglobin, epsilon 2 decreases expression EXP Mercaptopurine results in decreased expression of HBE2 mRNA CTD PMID:23358152 NCBI chr 1:169,000,133...169,001,761
Ensembl chr 1:169,000,133...169,001,761
JBrowse link
G Hbegf heparin-binding EGF-like growth factor decreases expression EXP Mercaptopurine results in decreased expression of HBEGF mRNA CTD PMID:23358152 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Heph hephaestin decreases expression EXP Mercaptopurine results in decreased expression of HEPH mRNA CTD PMID:23358152 NCBI chr  X:65,377,313...65,658,479
Ensembl chr  X:65,563,122...65,658,516
JBrowse link
G Hoxa13 homeo box A13 decreases expression EXP Mercaptopurine results in decreased expression of HOXA13 mRNA CTD PMID:23358152 Ensembl chr 4:82,228,017...82,229,397 JBrowse link
G Hpgds hematopoietic prostaglandin D synthase increases expression EXP Mercaptopurine results in increased expression of HPGDS mRNA CTD PMID:23358152 NCBI chr 4:95,945,356...95,970,666
Ensembl chr 4:95,946,025...95,970,666
JBrowse link
G Hpx hemopexin increases expression EXP Mercaptopurine results in increased expression of HPX mRNA CTD PMID:23358152 NCBI chr 1:170,423,558...170,431,066
Ensembl chr 1:170,423,483...170,431,073
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases expression EXP Mercaptopurine results in increased expression of HSD11B1 mRNA CTD PMID:23358152 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B increases expression EXP Mercaptopurine results in increased expression of HTR2B mRNA CTD PMID:23358152 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014
JBrowse link
G Htra3 HtrA serine peptidase 3 increases expression EXP Mercaptopurine results in increased expression of HTRA3 mRNA CTD PMID:23358152 NCBI chr14:80,248,140...80,276,534
Ensembl chr14:80,248,140...80,276,534
JBrowse link
G Htra4 HtrA serine peptidase 4 increases expression EXP Mercaptopurine results in increased expression of HTRA4 mRNA CTD PMID:23358152 NCBI chr16:71,784,819...71,802,765
Ensembl chr16:71,787,966...71,802,763
JBrowse link
G Ifit1 interferon-induced protein with tetratricopeptide repeats 1 increases expression EXP Mercaptopurine results in increased expression of IFIT1 mRNA CTD PMID:23358152 NCBI chr 1:252,944,105...252,946,170
Ensembl chr 1:252,944,103...252,946,170
JBrowse link
G Igsf11 immunoglobulin superfamily, member 11 increases expression EXP Mercaptopurine results in increased expression of IGSF11 mRNA CTD PMID:23358152 NCBI chr11:64,286,691...64,421,248
Ensembl chr11:64,286,694...64,421,248
JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression EXP Mercaptopurine results in increased expression of IL1RN mRNA CTD PMID:23358152 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il23r interleukin 23 receptor increases expression EXP Mercaptopurine results in increased expression of IL23R mRNA CTD PMID:23358152 NCBI chr 4:98,203,788...98,306,729
Ensembl chr 4:98,203,958...98,305,173
JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 increases expression ISO Mercaptopurine results in increased expression of IMPDH2 mRNA CTD PMID:18222062 NCBI chr 8:117,346,983...117,351,619
Ensembl chr 8:117,347,029...117,351,610
JBrowse link
G Ins2 insulin 2 decreases expression EXP Mercaptopurine results in decreased expression of INS2 mRNA CTD PMID:23358152 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Irx4 iroquois homeobox 4 decreases expression EXP Mercaptopurine results in decreased expression of IRX4 mRNA CTD PMID:23358152 NCBI chr 1:32,634,774...32,645,151
Ensembl chr 1:32,634,796...32,643,771
JBrowse link
G Jam2 junctional adhesion molecule 2 increases expression EXP Mercaptopurine results in increased expression of JAM2 mRNA CTD PMID:23358152 NCBI chr11:24,235,310...24,285,279
Ensembl chr11:24,266,345...24,285,275
JBrowse link
G Kcnmb4 potassium calcium-activated channel subfamily M regulatory beta subunit 4 increases expression EXP Mercaptopurine results in increased expression of KCNMB4 mRNA CTD PMID:23358152 NCBI chr 7:59,461,808...59,514,759
Ensembl chr 7:59,461,799...59,514,939
JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 decreases expression EXP Mercaptopurine results in decreased expression of KCNQ2 mRNA CTD PMID:23358152 NCBI chr 3:176,585,897...176,645,029
Ensembl chr 3:176,589,906...176,644,951
JBrowse link
G Kcnt1 potassium sodium-activated channel subfamily T member 1 increases expression EXP Mercaptopurine results in increased expression of KCNT1 mRNA CTD PMID:23358152 NCBI chr 3:3,310,641...3,366,558
Ensembl chr 3:3,310,954...3,365,340
JBrowse link
G Kif20a kinesin family member 20A decreases expression EXP Mercaptopurine results in decreased expression of KIF20A mRNA CTD PMID:23358152 NCBI chr18:27,424,328...27,432,814
Ensembl chr18:27,424,328...27,432,814
JBrowse link
G Kif23 kinesin family member 23 decreases expression EXP Mercaptopurine results in decreased expression of KIF23 mRNA CTD PMID:23358152 NCBI chr 8:66,866,043...66,893,241
Ensembl chr 8:66,866,082...66,893,196
JBrowse link
G Klhl40 kelch-like family member 40 increases expression EXP Mercaptopurine results in increased expression of KLHL40 mRNA CTD PMID:23358152 NCBI chr 8:130,416,265...130,421,871
Ensembl chr 8:130,416,355...130,421,871
JBrowse link
G Krt23 keratin 23 increases expression EXP Mercaptopurine results in increased expression of KRT23 mRNA CTD PMID:23358152 NCBI chr10:87,391,623...87,407,634
Ensembl chr10:87,391,623...87,407,634
JBrowse link
G L1td1 LINE-1 type transposase domain containing 1 decreases expression EXP Mercaptopurine results in decreased expression of L1TD1 mRNA CTD PMID:23358152 NCBI chr 5:117,347,998...117,361,012
Ensembl chr 5:117,354,794...117,360,654
JBrowse link
G Larp6 La ribonucleoprotein 6, translational regulator increases expression EXP Mercaptopurine results in increased expression of LARP6 mRNA CTD PMID:23358152 NCBI chr 8:65,611,570...65,632,706
Ensembl chr 8:65,611,570...65,632,706
JBrowse link
G Lipm lipase, family member M increases expression EXP Mercaptopurine results in increased expression of LIPM mRNA CTD PMID:23358152 NCBI chr 1:252,409,232...252,428,567
Ensembl chr 1:252,409,268...252,428,774
JBrowse link
G LOC100911204 protein CASC5-like decreases expression EXP Mercaptopurine results in decreased expression of KNL1 mRNA CTD PMID:23358152 NCBI chr 3:112,531,429...112,560,698
Ensembl chr 3:112,531,703...112,560,634
JBrowse link
G Lum lumican decreases expression EXP Mercaptopurine results in decreased expression of LUM mRNA CTD PMID:23358152 NCBI chr 7:38,820,058...38,826,862
Ensembl chr 7:38,819,771...38,826,862
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 decreases phosphorylation ISO Mercaptopurine results in decreased phosphorylation of MAP2K1 protein CTD PMID:12697733 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Mcpt10 mast cell protease 10 increases expression EXP Mercaptopurine results in increased expression of MCPT10 mRNA CTD PMID:23358152 NCBI chr15:34,644,471...34,647,497
Ensembl chr15:34,644,464...34,694,244
JBrowse link
G Mcpt1l2 mast cell protease 1-like 2 increases expression EXP Mercaptopurine results in increased expression of MCPT1L2 mRNA CTD PMID:23358152 NCBI chr15:34,633,988...34,636,186
Ensembl chr15:34,634,122...34,636,197
JBrowse link
G Mcpt1l4 mast cell protease 1-like 4 increases expression EXP Mercaptopurine results in increased expression of MCPT1L4 mRNA CTD PMID:23358152 NCBI chr15:35,001,603...35,004,403
Ensembl chr15:35,001,838...35,020,760
JBrowse link
G Mcpt8l2 mast cell protease 8-like 2 increases expression EXP Mercaptopurine results in increased expression of MCPT8L2 mRNA CTD PMID:23358152 NCBI chr15:34,622,126...34,625,079
Ensembl chr15:34,622,123...34,625,121
JBrowse link
G Mcpt8l3 mast cell protease 8-like 3 increases expression EXP Mercaptopurine results in increased expression of MCPT8L3 mRNA CTD PMID:23358152 NCBI chr15:34,667,266...34,670,303
Ensembl chr15:34,644,464...34,694,244
JBrowse link
G Meox2 mesenchyme homeobox 2 decreases expression EXP Mercaptopurine results in decreased expression of MEOX2 mRNA CTD PMID:23358152 NCBI chr 6:56,625,768...56,689,195
Ensembl chr 6:56,625,650...56,689,238
JBrowse link
G Mest mesoderm specific transcript decreases expression EXP Mercaptopurine results in decreased expression of MEST mRNA CTD PMID:23358152 NCBI chr 4:58,052,786...58,063,227
Ensembl chr 4:58,053,041...58,063,138
JBrowse link
G Mfap3l microfibril associated protein 3 like increases expression EXP Mercaptopurine results in increased expression of MFAP3L mRNA CTD PMID:23358152 NCBI chr16:32,734,059...32,777,091
Ensembl chr16:32,738,265...32,753,278
JBrowse link
G Mir10b microRNA 10b increases expression EXP Mercaptopurine results in increased expression of MIR10B mRNA CTD PMID:23358152 NCBI chr 3:61,647,978...61,648,086
Ensembl chr 3:61,647,978...61,648,086
JBrowse link
G Mir142 microRNA 142 decreases expression EXP Mercaptopurine results in decreased expression of MIR142 mRNA CTD PMID:23358152 NCBI chr10:75,050,839...75,050,925
Ensembl chr10:75,050,832...75,050,942
JBrowse link
G Mir144 microRNA 144 decreases expression EXP Mercaptopurine results in decreased expression of MIR144 mRNA CTD PMID:23358152 NCBI chr10:65,291,365...65,291,447
Ensembl chr10:65,291,365...65,291,447
JBrowse link
G Mir146b microRNA 146b increases expression EXP Mercaptopurine results in increased expression of MIR146B mRNA CTD PMID:23358152 NCBI chr 1:266,089,488...266,089,575
Ensembl chr 1:266,089,488...266,089,575
JBrowse link
G Mir195 microRNA 195 increases expression EXP Mercaptopurine results in increased expression of MIR195 mRNA CTD PMID:23358152 NCBI chr10:56,845,301...56,845,387
Ensembl chr10:56,845,301...56,845,387
JBrowse link
G Mir196b microRNA 196b increases expression EXP Mercaptopurine results in increased expression of MIR196B mRNA CTD PMID:23358152 NCBI chr 4:82,199,056...82,199,140
Ensembl chr 4:82,199,056...82,199,140
JBrowse link
G Mir21 microRNA 21 increases expression EXP Mercaptopurine results in increased expression of MIR21 mRNA CTD PMID:23358152 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir23a microRNA 23a increases expression EXP Mercaptopurine results in increased expression of MIR23A mRNA CTD PMID:23358152 NCBI chr19:25,318,582...25,318,656
Ensembl chr19:25,318,582...25,318,656
JBrowse link
G Mir290 microRNA 290 decreases expression EXP Mercaptopurine results in decreased expression of MIR292 mRNA CTD PMID:23358152 NCBI chr 1:64,538,705...64,538,785
Ensembl chr 1:64,538,705...64,538,785
JBrowse link
G Mir29a microRNA 29a increases expression EXP Mercaptopurine results in increased expression of MIR29A mRNA CTD PMID:23358152 NCBI chr 4:58,343,931...58,344,018 JBrowse link
G Mir31 microRNA 31 increases expression EXP Mercaptopurine results in increased expression of MIR31 mRNA CTD PMID:23358152 NCBI chr 5:107,206,515...107,206,620 JBrowse link
G Mir345 microRNA 345 increases expression EXP Mercaptopurine results in increased expression of MIR345 mRNA CTD PMID:23358152 NCBI chr 6:132,748,968...132,749,063
Ensembl chr 6:132,748,968...132,749,063
JBrowse link
G Mir34a microRNA 34a increases expression EXP Mercaptopurine results in increased expression of MIR34A mRNA CTD PMID:23358152 NCBI chr 5:167,092,491...167,092,592
Ensembl chr 5:167,092,491...167,092,592
JBrowse link
G Mir451a microRNA 451a decreases expression EXP Mercaptopurine results in decreased expression of MIR451A mRNA CTD PMID:23358152 NCBI chr10:65,291,204...65,291,275
Ensembl chr10:65,291,204...65,291,275
JBrowse link
G Mir497 microRNA 497 increases expression EXP Mercaptopurine results in increased expression of MIR497 mRNA CTD PMID:23358152 NCBI chr10:56,844,977...56,845,045
Ensembl chr10:56,844,977...56,845,045
JBrowse link
G Mirlet7b microRNA let-7b increases expression EXP Mercaptopurine results in increased expression of MIRLET7B mRNA CTD PMID:23358152 NCBI chr 7:126,590,627...126,590,711
Ensembl chr 7:126,590,627...126,590,711
JBrowse link
G Mmp10 matrix metallopeptidase 10 increases expression EXP Mercaptopurine results in increased expression of MMP10 mRNA CTD PMID:23358152 NCBI chr 8:5,734,348...5,742,243
Ensembl chr 8:5,734,348...5,742,243
JBrowse link
G Mmp7 matrix metallopeptidase 7 increases expression EXP Mercaptopurine results in increased expression of MMP7 mRNA CTD PMID:23358152 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mocos molybdenum cofactor sulfurase decreases oxidation
multiple interactions
ISO MOCOS gene SNP results in decreased oxidation of Mercaptopurine
[MOCOS gene SNP results in decreased oxidation of Mercaptopurine] which results in decreased chemical synthesis of 6-thiouric acid; [MOCOS gene SNP results in decreased oxidation of Mercaptopurine] which results in decreased chemical synthesis of 6-thioxanthine; [MOCOS gene SNP results in decreased oxidation of Mercaptopurine] which results in increased chemical synthesis of Thioguanine
CTD PMID:29935280 NCBI chr18:16,590,086...16,636,312
Ensembl chr18:16,590,197...16,636,084
JBrowse link
G Msx2 msh homeobox 2 decreases expression EXP Mercaptopurine results in decreased expression of MSX2 mRNA CTD PMID:23358152 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527
JBrowse link
G Mt2A metallothionein 2A increases expression EXP Mercaptopurine results in increased expression of MT2A mRNA CTD PMID:23358152 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mt3 metallothionein 3 increases expression EXP Mercaptopurine results in increased expression of MT3 mRNA CTD PMID:23358152 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Mvp major vault protein decreases response to substance ISO MVP results in decreased susceptibility to Mercaptopurine CTD PMID:19232821 NCBI chr 1:198,420,813...198,448,612
Ensembl chr 1:198,420,806...198,450,047
JBrowse link
G Myh6 myosin heavy chain 6 decreases expression EXP Mercaptopurine results in decreased expression of MYH6 mRNA CTD PMID:23358152 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699
JBrowse link
G Myl7 myosin light chain 7 increases expression EXP Mercaptopurine results in increased expression of MYL7 mRNA CTD PMID:23358152 NCBI chr14:86,144,770...86,147,075
Ensembl chr14:86,143,862...86,147,553
JBrowse link
G Myo16 myosin XVI increases expression EXP Mercaptopurine results in increased expression of MYO16 mRNA CTD PMID:23358152 NCBI chr16:84,575,149...85,177,834
Ensembl chr16:84,575,150...84,939,323
JBrowse link
G Nasp nuclear autoantigenic sperm protein decreases expression EXP Mercaptopurine results in decreased expression of NASP mRNA CTD PMID:23358152 NCBI chr 5:135,446,485...135,472,113
Ensembl chr 5:135,446,962...135,472,116
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Mercaptopurine inhibits the reaction [CD28 protein results in increased activity of [NFKB1 protein binds to RELA protein]] CTD PMID:12697733 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression
multiple interactions
EXP Mercaptopurine results in increased expression of NR4A2 mRNA
[GW 1929 co-treated with Mercaptopurine] results in increased expression of NR4A2 mRNA; [GW 1929 co-treated with Mercaptopurine] results in increased expression of NR4A2 protein; Mercaptopurine results in increased expression of and affects the localization of NR4A2 protein
CTD PMID:27435855 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Ntf3 neurotrophin 3 increases expression EXP Mercaptopurine results in increased expression of NTF3 mRNA CTD PMID:23358152 NCBI chr 4:158,636,883...158,705,886
Ensembl chr 4:158,636,884...158,705,886
JBrowse link
G Nudt15 nudix hydrolase 15 increases response to substance ISO NUDT15 gene SNP results in increased susceptibility to Mercaptopurine CTD PMID:25108385 NCBI chr15:55,417,774...55,456,698
Ensembl chr15:55,419,502...55,456,698
JBrowse link
G Ogn osteoglycin decreases expression EXP Mercaptopurine results in decreased expression of OGN mRNA CTD PMID:23358152 NCBI chr17:14,607,442...14,628,274
Ensembl chr17:15,447,716...15,467,359
Ensembl chr17:15,447,716...15,467,359
JBrowse link
G Olah oleoyl-ACP hydrolase increases expression EXP Mercaptopurine results in increased expression of OLAH mRNA CTD PMID:23358152 NCBI chr17:78,878,673...78,903,919
Ensembl chr17:78,879,058...78,903,967
JBrowse link
G Orm1 orosomucoid 1 increases expression EXP Mercaptopurine results in increased expression of ORM1 mRNA CTD PMID:23358152 NCBI chr 5:79,179,668...79,182,820
Ensembl chr 5:79,179,417...79,182,820
JBrowse link
G Pacsin1 protein kinase C and casein kinase substrate in neurons 1 decreases expression EXP Mercaptopurine results in decreased expression of PACSIN1 mRNA CTD PMID:23358152 NCBI chr20:7,241,248...7,286,702
Ensembl chr20:7,279,820...7,286,586
JBrowse link
G Pcdh19 protocadherin 19 decreases expression EXP Mercaptopurine results in decreased expression of PCDH19 mRNA CTD PMID:23358152 NCBI chr  X:104,387,346...104,493,914
Ensembl chr  X:104,391,607...104,493,757
JBrowse link
G Peli2 pellino E3 ubiquitin protein ligase family member 2 increases expression EXP Mercaptopurine results in increased expression of PELI2 mRNA CTD PMID:23358152 NCBI chr15:24,942,218...25,086,350
Ensembl chr15:24,942,218...25,083,931
JBrowse link
G Penk proenkephalin decreases expression EXP Mercaptopurine results in decreased expression of PENK mRNA CTD PMID:23358152 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837
JBrowse link
G Pgr progesterone receptor increases expression EXP Mercaptopurine results in increased expression of PGR mRNA CTD PMID:23358152 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Phactr3 phosphatase and actin regulator 3 increases expression EXP Mercaptopurine results in increased expression of PHACTR3 mRNA CTD PMID:23358152 NCBI chr 3:173,798,542...173,871,386
Ensembl chr 3:173,798,545...173,871,904
JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 decreases expression EXP Mercaptopurine results in decreased expression of PHLDA2 mRNA CTD PMID:23358152 NCBI chr 1:216,701,345...216,704,479
Ensembl chr 1:216,702,319...216,703,534
JBrowse link
G Pi16 peptidase inhibitor 16 increases expression EXP Mercaptopurine results in increased expression of PI16 mRNA CTD PMID:23358152 NCBI chr20:6,923,176...6,932,786
Ensembl chr20:6,923,489...6,932,786
JBrowse link
G Pimreg PICALM interacting mitotic regulator decreases expression EXP Mercaptopurine results in decreased expression of PIMREG mRNA CTD PMID:23358152 NCBI chr10:58,613,588...58,618,524
Ensembl chr10:58,613,674...58,618,514
JBrowse link
G Pinlyp phospholipase A2 inhibitor and LY6/PLAUR domain containing increases expression EXP Mercaptopurine results in increased expression of PINLYP mRNA CTD PMID:23358152 NCBI chr 1:81,406,632...81,412,602
Ensembl chr 1:81,406,576...81,412,251
JBrowse link
G Pla2g10 phospholipase A2, group X decreases expression EXP Mercaptopurine results in decreased expression of PLA2G10 mRNA CTD PMID:23358152 NCBI chr10:1,509,732...1,520,970
Ensembl chr10:1,509,732...1,520,970
JBrowse link
G Plekhd1 pleckstrin homology and coiled-coil domain containing D1 decreases expression EXP Mercaptopurine results in decreased expression of PLEKHD1 mRNA CTD PMID:23358152 NCBI chr 6:104,340,114...104,371,162
Ensembl chr 6:104,340,206...104,371,335
JBrowse link
G Prf1 perforin 1 increases expression EXP Mercaptopurine results in increased expression of PRF1 mRNA CTD PMID:23358152 NCBI chr20:30,915,294...30,920,804
Ensembl chr20:30,915,213...30,921,382
JBrowse link
G Prl5a2 prolactin family 5, subfamily a, member 2 increases expression EXP Mercaptopurine results in increased expression of PRL5A2 mRNA CTD PMID:23358152 NCBI chr17:38,456,016...38,462,358
Ensembl chr17:38,456,073...38,462,352
JBrowse link
G Prlr prolactin receptor decreases expression EXP Mercaptopurine results in decreased expression of PRLR mRNA CTD PMID:23358152 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin decreases expression EXP Mercaptopurine results in decreased expression of PTTG1 mRNA CTD PMID:23358152 NCBI chr10:29,014,332...29,026,088
Ensembl chr10:29,020,049...29,026,002
JBrowse link
G Rec8 REC8 meiotic recombination protein decreases expression EXP Mercaptopurine results in decreased expression of REC8 mRNA CTD PMID:23358152 NCBI chr15:34,296,922...34,304,387
Ensembl chr15:34,296,922...34,304,552
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
affects localization
ISO Mercaptopurine inhibits the reaction [CD28 protein results in increased activity of [NFKB1 protein binds to RELA protein]]
Mercaptopurine affects the localization of RELA protein
CTD PMID:12697733 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Retn resistin increases expression EXP Mercaptopurine results in increased expression of RETN mRNA CTD PMID:23358152 NCBI chr12:2,201,909...2,203,649
Ensembl chr12:2,201,891...2,204,249
JBrowse link
G Rflnb refilin B decreases expression EXP Mercaptopurine results in decreased expression of RFLNB mRNA CTD PMID:23358152 NCBI chr10:64,196,103...64,202,380
Ensembl chr10:64,196,127...64,202,380
JBrowse link
G RGD1307595 similar to RIKEN cDNA 1700018B24 decreases expression EXP Mercaptopurine results in decreased expression of RGD1307595 mRNA CTD PMID:23358152 NCBI chr 2:138,194,136...138,197,442
Ensembl chr 2:138,194,136...138,197,442
JBrowse link
G RGD1309350 similar to transthyretin (4L369) decreases expression EXP Mercaptopurine results in decreased expression of RGD1309350 mRNA CTD PMID:23358152 NCBI chr 1:213,577,202...213,580,598
Ensembl chr 1:213,577,122...213,580,542
JBrowse link
G RGD1560559 similar to RIKEN cDNA 2310042E22 increases expression EXP Mercaptopurine results in increased expression of RGD1560559 mRNA CTD PMID:23358152 NCBI chr11:83,675,801...83,677,157
Ensembl chr11:83,676,072...83,676,952
JBrowse link
G RGD1562035 similar to mast cell protease 1-like 3 precursor increases expression EXP Mercaptopurine results in increased expression of RGD1562035 mRNA CTD PMID:23358152
G Rgs1 regulator of G-protein signaling 1 increases expression EXP Mercaptopurine results in increased expression of RGS1 mRNA CTD PMID:23358152 NCBI chr13:61,066,196...61,070,772
Ensembl chr13:61,066,153...61,070,599
JBrowse link
G Rho rhodopsin increases expression EXP Mercaptopurine results in increased expression of RHO mRNA CTD PMID:23358152 NCBI chr 4:147,832,136...147,837,298
Ensembl chr 4:147,832,136...147,837,298
JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator decreases expression EXP Mercaptopurine results in decreased expression of RRAD mRNA CTD PMID:23358152 NCBI chr19:561,696...564,929
Ensembl chr19:561,727...564,930
JBrowse link
G RT1-Ba RT1 class II, locus Ba affects response to substance ISO HLA-DQA1 gene polymorphism affects the susceptibility to Mercaptopurine CTD PMID:25217962 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 decreases expression
affects response to substance
EXP
ISO
Mercaptopurine results in decreased expression of RT1-DB1 mRNA
HLA-DRB1 gene polymorphism affects the susceptibility to Mercaptopurine
CTD PMID:23358152, PMID:25217962 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
JBrowse link
G Rtl1 retrotransposon-like 1 decreases expression EXP Mercaptopurine results in decreased expression of RTL1 mRNA CTD PMID:23358152 NCBI chr 6:133,710,207...133,721,191 JBrowse link
G Rtn4rl1 reticulon 4 receptor-like 1 increases expression EXP Mercaptopurine results in increased expression of RTN4RL1 mRNA CTD PMID:23358152 NCBI chr10:62,035,866...62,109,075
Ensembl chr10:62,035,866...62,109,078
JBrowse link
G S100a16 S100 calcium binding protein A16 decreases expression EXP Mercaptopurine results in decreased expression of S100A16 mRNA CTD PMID:23358152 NCBI chr 2:189,923,140...189,928,850
Ensembl chr 2:189,922,996...189,928,848
JBrowse link
G S100b S100 calcium binding protein B increases expression EXP Mercaptopurine results in increased expression of S100B mRNA CTD PMID:23358152 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G S100z S100 calcium binding protein Z decreases expression EXP Mercaptopurine results in decreased expression of S100Z mRNA CTD PMID:23358152 NCBI chr 2:25,188,381...25,203,627
Ensembl chr 2:25,188,782...25,190,495
JBrowse link
G Satb1 SATB homeobox 1 decreases expression EXP Mercaptopurine results in decreased expression of SATB1 mRNA CTD PMID:23358152 NCBI chr 9:2,181,135...2,277,949
Ensembl chr 9:2,190,915...2,274,629
JBrowse link
G Sbspon somatomedin B and thrombospondin, type 1 domain containing decreases expression EXP Mercaptopurine results in decreased expression of SBSPON mRNA CTD PMID:23358152 NCBI chr 5:2,813,004...2,847,697
Ensembl chr 5:2,813,131...2,843,483
JBrowse link
G Scamp5 secretory carrier membrane protein 5 decreases expression EXP Mercaptopurine results in decreased expression of SCAMP5 mRNA CTD PMID:23358152 NCBI chr 8:62,221,820...62,266,269
Ensembl chr 8:62,220,892...62,248,017
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP Mercaptopurine results in decreased expression of SCD1 mRNA CTD PMID:23358152 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Scg5 secretogranin V increases expression EXP Mercaptopurine results in increased expression of SCG5 mRNA CTD PMID:23358152 NCBI chr 3:105,235,065...105,279,475
Ensembl chr 3:105,235,050...105,279,462
JBrowse link
G Scube3 signal peptide, CUB domain and EGF like domain containing 3 increases expression EXP Mercaptopurine results in increased expression of SCUBE3 mRNA CTD PMID:23358152 NCBI chr20:7,718,260...7,749,847
Ensembl chr20:7,718,282...7,746,331
JBrowse link
G Sftpc surfactant protein C increases expression EXP Mercaptopurine results in increased expression of SFTPC mRNA CTD PMID:23358152 NCBI chr15:52,211,538...52,214,480
Ensembl chr15:52,211,544...52,214,616
JBrowse link
G Shcbp1l SHC binding and spindle associated 1 like increases expression EXP Mercaptopurine results in increased expression of SHCBP1L mRNA CTD PMID:23358152 NCBI chr13:70,852,044...70,882,336
Ensembl chr13:70,852,023...70,882,340
JBrowse link
G Shisa3 shisa family member 3 increases expression EXP Mercaptopurine results in increased expression of SHISA3 mRNA CTD PMID:23358152 NCBI chr14:42,216,653...42,221,225
Ensembl chr14:42,216,654...42,221,225
JBrowse link
G Shisa8 shisa family member 8 decreases expression EXP Mercaptopurine results in decreased expression of SHISA8 mRNA CTD PMID:23358152 NCBI chr 7:123,440,163...123,445,613
Ensembl chr 7:123,440,163...123,445,613
JBrowse link
G Slc22a3 solute carrier family 22 member 3 decreases expression EXP Mercaptopurine results in decreased expression of SLC22A3 mRNA CTD PMID:23358152 NCBI chr 1:48,433,079...48,521,261
Ensembl chr 1:48,433,079...48,521,256
JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases transport ISO SLC22A8 protein results in increased transport of Mercaptopurine CTD PMID:15100168 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
G Slc2a2 solute carrier family 2 member 2 decreases expression EXP Mercaptopurine results in decreased expression of SLC2A2 mRNA CTD PMID:23358152 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Slc2a3 solute carrier family 2 member 3 decreases expression EXP Mercaptopurine results in decreased expression of SLC2A3 mRNA CTD PMID:23358152 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
JBrowse link
G Slc35g1 solute carrier family 35, member G1 decreases expression EXP Mercaptopurine results in decreased expression of SLC35G1 mRNA CTD PMID:23358152 NCBI chr 1:257,076,221...257,082,655
Ensembl chr 1:257,076,221...257,082,655
JBrowse link
G Slc38a5 solute carrier family 38, member 5 decreases expression EXP Mercaptopurine results in decreased expression of SLC38A5 mRNA CTD PMID:23358152 NCBI chr  X:14,963,919...14,972,675
Ensembl chr  X:14,963,921...14,972,675
JBrowse link
G Slc5a5 solute carrier family 5 member 5 decreases expression EXP Mercaptopurine results in decreased expression of SLC5A5 mRNA CTD PMID:23358152 NCBI chr16:20,297,414...20,307,401
Ensembl chr16:20,297,414...20,307,400
JBrowse link
G Slc7a14 solute carrier family 7, member 14 decreases expression EXP Mercaptopurine results in decreased expression of SLC7A14 mRNA CTD PMID:23358152 NCBI chr 2:115,678,344...115,788,688
Ensembl chr 2:115,678,344...115,788,687
JBrowse link
G Slc9a2 solute carrier family 9 member A2 decreases expression EXP Mercaptopurine results in decreased expression of SLC9A2 mRNA CTD PMID:23358152 NCBI chr 9:47,386,581...47,491,813
Ensembl chr 9:47,386,626...47,491,907
JBrowse link
G Smoc2 SPARC related modular calcium binding 2 decreases expression EXP Mercaptopurine results in decreased expression of SMOC2 mRNA CTD PMID:23358152 NCBI chr 1:56,242,289...56,374,106
Ensembl chr 1:56,242,346...56,374,120
JBrowse link
G Sncg synuclein, gamma decreases expression EXP Mercaptopurine results in decreased expression of SNCG mRNA CTD PMID:23358152 NCBI chr16:10,722,110...10,726,648
Ensembl chr16:10,722,106...10,726,707
JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO Mercaptopurine results in increased expression of SOD2 mRNA CTD PMID:18222062 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sorcs2 sortilin-related VPS10 domain containing receptor 2 increases expression EXP Mercaptopurine results in increased expression of SORCS2 mRNA CTD PMID:23358152 NCBI chr14:79,538,911...79,912,333
Ensembl chr14:79,538,911...79,912,333
JBrowse link
G Sostdc1 sclerostin domain containing 1 decreases expression EXP Mercaptopurine results in decreased expression of SOSTDC1 mRNA CTD PMID:23358152 NCBI chr 6:55,812,820...55,816,994
Ensembl chr 6:55,812,747...55,817,066
JBrowse link
G Spink5 serine peptidase inhibitor, Kazal type 5 increases expression EXP Mercaptopurine results in increased expression of SPINK5 mRNA CTD PMID:23358152 NCBI chr18:35,118,300...35,190,458
Ensembl chr18:35,121,967...35,191,069
Ensembl chr 1:35,121,967...35,191,069
JBrowse link
G Stfa2l2 stefin A2-like 2 increases expression EXP Mercaptopurine results in increased expression of STFA2L2 mRNA CTD PMID:23358152 NCBI chr11:67,451,583...67,454,007 JBrowse link
G Synm synemin increases expression EXP Mercaptopurine results in increased expression of SYNM mRNA CTD PMID:23358152 NCBI chr 1:128,692,112...128,722,048
Ensembl chr 1:128,692,112...128,722,048
JBrowse link
G Tac3 tachykinin precursor 3 decreases expression EXP Mercaptopurine results in decreased expression of TAC2 mRNA CTD PMID:23358152 NCBI chr 7:71,023,976...71,030,582
Ensembl chr 7:71,023,976...71,030,582
JBrowse link
G Testin testin gene increases expression EXP Mercaptopurine results in increased expression of TESTIN mRNA CTD PMID:23358152 NCBI chr17:4,194,796...4,225,376
Ensembl chr17:4,212,890...4,225,376
JBrowse link
G Tex10 testis expressed 10 decreases expression EXP Mercaptopurine results in decreased expression of TEX10 mRNA CTD PMID:23358152 NCBI chr 5:64,179,247...64,225,844
Ensembl chr 5:64,179,247...64,225,844
JBrowse link
G Tfcp2l1 transcription factor CP2-like 1 decreases expression EXP Mercaptopurine results in decreased expression of TFCP2L1 mRNA CTD PMID:23358152 NCBI chr13:34,610,689...34,671,617
Ensembl chr13:34,610,684...34,670,124
JBrowse link
G Tfrc transferrin receptor decreases expression EXP Mercaptopurine results in decreased expression of TFRC mRNA CTD PMID:23358152 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP [GW 1929 co-treated with Mercaptopurine] inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein]; Mercaptopurine inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] CTD PMID:27435855 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Thbs4 thrombospondin 4 increases expression EXP Mercaptopurine results in increased expression of THBS4 mRNA CTD PMID:23358152 NCBI chr 2:22,343,727...22,385,855
Ensembl chr 2:22,343,727...22,385,855
JBrowse link
G Them5 thioesterase superfamily member 5 increases expression EXP Mercaptopurine results in increased expression of THEM5 mRNA CTD PMID:23358152 NCBI chr 2:195,582,781...195,588,000
Ensembl chr 2:195,582,781...195,588,000
JBrowse link
G Tm4sf20 transmembrane 4 L six family member 20 decreases expression EXP Mercaptopurine results in decreased expression of TM4SF20 mRNA CTD PMID:23358152 NCBI chr 9:88,521,193...88,534,710
Ensembl chr 9:88,521,193...88,534,710
JBrowse link
G Tmcc2 transmembrane and coiled-coil domain family 2 decreases expression EXP Mercaptopurine results in decreased expression of TMCC2 mRNA CTD PMID:23358152 NCBI chr13:49,132,685...49,169,771
Ensembl chr13:49,132,667...49,169,918
JBrowse link
G Tmem100 transmembrane protein 100 decreases expression EXP Mercaptopurine results in decreased expression of TMEM100 mRNA CTD PMID:23358152 NCBI chr10:77,537,340...77,543,710
Ensembl chr10:77,537,340...77,543,192
JBrowse link
G Tmprss7 transmembrane serine protease 7 increases expression EXP Mercaptopurine results in increased expression of TMPRSS7 mRNA CTD PMID:23358152 NCBI chr11:60,102,125...60,138,065
Ensembl chr11:60,102,121...60,138,059
JBrowse link
G Tpmt thiopurine S-methyltransferase affects response to substance
affects metabolic processing
ISO TPMT gene polymorphism affects the susceptibility to Mercaptopurine
TPMT protein affects the metabolism of Mercaptopurine
CTD PMID:12509611, PMID:14505127 NCBI chr17:18,029,090...18,047,716
Ensembl chr17:18,029,124...18,047,714
JBrowse link
G Trh thyrotropin releasing hormone increases expression EXP Mercaptopurine results in increased expression of TRH mRNA CTD PMID:23358152 NCBI chr 4:124,110,716...124,113,242
Ensembl chr 4:124,110,716...124,113,242
JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 increases expression EXP Mercaptopurine results in increased expression of TRPV6 mRNA CTD PMID:23358152 NCBI chr 4:70,918,631...70,934,291
Ensembl chr 4:70,918,632...70,934,295
JBrowse link
G Tspan11 tetraspanin 11 decreases expression EXP Mercaptopurine results in decreased expression of TSPAN11 mRNA CTD PMID:23358152 NCBI chr 4:160,455,845...160,522,905
Ensembl chr 4:160,455,986...160,522,904
JBrowse link
G Tyms thymidylate synthetase affects response to substance ISO TYMS gene polymorphism affects the susceptibility to Mercaptopurine CTD PMID:15713801 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
G Ubd ubiquitin D increases expression EXP Mercaptopurine results in increased expression of UBD mRNA CTD PMID:23358152 NCBI chr20:1,876,175...1,878,126
Ensembl chr20:1,876,173...1,897,814
JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 increases expression ISO Mercaptopurine results in increased expression of VAV1 protein CTD PMID:12697733 NCBI chr 9:9,617,551...9,675,167
Ensembl chr 9:9,617,786...9,675,110
JBrowse link
G Vdr vitamin D receptor affects response to substance ISO VDR gene polymorphism affects the susceptibility to Mercaptopurine CTD PMID:15713801 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Vgf VGF nerve growth factor inducible increases expression EXP Mercaptopurine results in increased expression of VGF mRNA CTD PMID:23358152 NCBI chr12:22,677,302...22,680,630
Ensembl chr12:22,677,607...22,680,630
JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 decreases expression EXP Mercaptopurine results in decreased expression of VIPR2 mRNA CTD PMID:23358152 NCBI chr 6:143,932,960...144,009,476
Ensembl chr 6:143,938,040...144,008,072
JBrowse link
G Vom2r12 vomeronasal 2 receptor, 12 decreases expression EXP Mercaptopurine results in decreased expression of VOM2R12 mRNA CTD PMID:23358152 NCBI chr 1:64,849,657...64,950,897
Ensembl chr 1:64,849,657...64,975,956
JBrowse link
G Wfdc1 WAP four-disulfide core domain 1 increases expression EXP Mercaptopurine results in increased expression of WFDC1 mRNA CTD PMID:23358152 NCBI chr19:52,313,771...52,332,721
Ensembl chr19:52,313,795...52,332,697
JBrowse link
G Wfdc2 WAP four-disulfide core domain 2 decreases expression EXP Mercaptopurine results in decreased expression of WFDC2 mRNA CTD PMID:23358152 NCBI chr 3:161,018,497...161,045,469
Ensembl chr 3:161,018,511...161,024,209
JBrowse link
G Wnt10b Wnt family member 10B decreases expression EXP Mercaptopurine results in decreased expression of WNT10B mRNA CTD PMID:23358152 NCBI chr 7:140,448,284...140,466,159
Ensembl chr 7:140,448,465...140,454,268
JBrowse link
G Wnt2b Wnt family member 2B decreases expression EXP Mercaptopurine results in decreased expression of WNT2B mRNA CTD PMID:23358152 NCBI chr 2:207,433,771...207,457,094
Ensembl chr 2:207,440,886...207,455,258
JBrowse link
G Wt1 WT1 transcription factor increases expression EXP Mercaptopurine results in increased expression of WT1 mRNA CTD PMID:23358152 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
G Xdh xanthine dehydrogenase increases expression
affects expression
EXP Mercaptopurine results in increased expression of XDH mRNA
Mercaptopurine affects the expression of XDH mRNA
CTD PMID:22688000, PMID:23358152 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
G Xkrx XK related, X-linked decreases expression EXP Mercaptopurine results in decreased expression of XKRX mRNA CTD PMID:23358152 NCBI chr  X:104,973,083...104,984,261
Ensembl chr  X:104,968,582...104,984,341
JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 increases expression EXP Mercaptopurine results in increased expression of ZBTB16 mRNA CTD PMID:23358152 NCBI chr 8:52,980,226...53,146,765
Ensembl chr 8:52,985,313...53,146,953
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 increases expression EXP Mercaptopurine results in increased expression of ZEB2 mRNA CTD PMID:23358152 NCBI chr 3:29,857,289...29,985,932
Ensembl chr 3:29,862,473...29,996,865
JBrowse link
G Zic3 Zic family member 3 decreases expression EXP Mercaptopurine results in decreased expression of ZIC3 mRNA CTD PMID:23358152 NCBI chr  X:140,875,191...140,888,344
Ensembl chr  X:140,878,216...140,888,795
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      biological role 19758
        biochemical role 19304
          antimetabolite 8495
            mercaptopurine 283
              mercaptopurine hydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic molecule 19514
                              organic cyclic compound 19311
                                organic heterocyclic compound 18425
                                  organic heteropolycyclic compound 17838
                                    organic heterobicyclic compound 16763
                                      imidazopyrimidine 5444
                                        purines 5442
                                          mercaptopurine 283
                                            mercaptopurine hydrate 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.