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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 3.5.1.5 (urease) inhibitor
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Accession:CHEBI:50635 term browser browse the term
Definition:EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the activity of urease (EC 3.5.1.5), reducing hydrolysis.
Synonyms:related_synonym: EC 3.5.1.5 inhibitor;   EC 3.5.1.5 inhibitors;   urea amidohydrolase inhibitor;   urea amidohydrolase inhibitors;   urease (EC 3.5.1.5) inhibitors;   urease inhibitor;   urease inhibitors



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acetohydroxamic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp12 matrix metallopeptidase 12 multiple interactions ISO acetohydroxamic acid binds to and results in decreased activity of MMP12 protein CTD PMID:17269766 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
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salicylhydroxamic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tpo thyroid peroxidase decreases activity EXP salicylhydroxamic acid results in decreased activity of TPO protein CTD PMID:26884060 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        biochemical role 19368
          enzyme inhibitor 18380
            EC 3.* (hydrolase) inhibitor 17925
              EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor 17804
                EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor 17804
                  EC 3.5.1.5 (urease) inhibitor 2
                    Euphorbia diterpenoid 2 0
                    acetohydroxamic acid 1
                    monastrol 0
                    salicylhydroxamic acid 1
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