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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cyclooxygenase 1 inhibitor
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Accession:CHEBI:50630 term browser browse the term
Definition:A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 1.
Synonyms:related_synonym: COX-1 inhibitor;   COX-1 inhibitors;   PTGS1 inhibitor;   PTGS1 inhibitors;   cyclo-oxygenase 1 inhibitor;   cyclo-oxygenase 1 inhibitors;   cyclooxygenase 1 inhibitors;   prostaglandin G/H synthase 1 inhibitor;   prostaglandin G/H synthase 1 inhibitors;   prostaglandin H2 synthase 1 inhibitor;   prostaglandin H2 synthase 1 inhibitors;   prostaglandin-endoperoxide synthase 1 inhibitor;   prostaglandin-endoperoxide synthase 1 inhibitors
 xref: Wikipedia:PTGS1



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      CHEBI ontology 19800
        role 19751
          biological role 19751
            biochemical role 19368
              enzyme inhibitor 18380
                EC 1.* (oxidoreductase) inhibitor 16719
                  EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor 14297
                    EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor 12612
                      EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor 12611
                        cyclooxygenase 1 inhibitor 10959
                          (+)-conocarpan 2
                          (+)-epicatechin + 58
                          (-)-larreatricin 0
                          (2S,3S)-2,3-dihydro-3-hydroxymethyl-2-(4-hydroxyphenyl)-5-(E)-propenylbenzofuran 0
                          (S)-ketorolac + 18
                          1-(4'-hydroxy-3'-methoxyphenyl)-7-phenyl-3-heptanone 0
                          13,14,15,16-tetranorlabdane-8alpha,12,18-triol 0
                          2-(2,4-dihydroxyphenyl)-5-(E)-propenylbenzofuran 0
                          2-(2-hydroxy-4-methoxyphenyl)-5-(3-hydroxypropyl)benzofuran 0
                          2-(4-hydroxyphenyl)-5-(E)-propenylbenzofuran 0
                          5-(3-hydroxypropyl)-2-(2-methoxy-4-hydroxyphenyl)benzofuran 0
                          8alpha,19-dihydroxylabd-13E-ene-15-oic acid 0
                          SC560 0
                          acetylsalicylic acid + 654
                          amfenac + 15
                          amfenac sodium hydrate 0
                          centaureidin 0
                          dexketoprofen 0
                          droxicam 0
                          fenoprofen 16
                          fenoprofen calcium 0
                          fenoprofen calcium (anhydrous) + 0
                          fomitopinic acid A 0
                          fomitoside E 0
                          fomitoside F 0
                          ibuprofen + 291
                          ipomotaoside A 0
                          ketorolac 18
                          ketorolac tromethamine 4
                          lupulin A 0
                          meso-3,3'-didemethoxynectandrin B 0
                          multifidol glucoside 0
                          myricetin + 114
                          naproxen + 110
                          naproxen sodium 0
                          nepafenac 0
                          nitroflurbiprofen 7
                          oleocanthal 0
                          paracetamol + 10702
                          piroxicam + 586
                          quercetin 4'-O-alpha-L-rhamnopyranosyl-3-O-beta-D-allopyranoside 0
                          rataniaphenol I 0
                          rataniaphenol II 0
                          rataniaphenol III 0
                          sodium (2-amino-3-benzoylphenyl)acetate + 0
                          sophoraisoflavanone A 0
                          valerylsalicylic acid 0
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