Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:1-naphthylamine
go back to main search page
Accession:CHEBI:50450 term browser browse the term
Definition:A naphthylamine that is naphthalene substituted by an amino group at position 1.
Synonyms:exact_synonym: naphthalen-1-amine
 related_synonym: 1-Naphthylamin;   1-aminonaphthalene;   1-naftilamina;   1-naphthalamine;   1-naphthalenamine;   Formula=C10H9N;   InChI=1S/C10H9N/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,11H2;   InChIKey=RUFPHBVGCFYCNW-UHFFFAOYSA-N;   SMILES=Nc1cccc2ccccc12;   alpha-aminonaphthalene;   alpha-naphthylamine;   naphthalen-1-ylamine
 alt_id: CHEBI:34098;   CHEBI:50449
 xref: Beilstein:386133;   CAS:134-32-7;   Gmelin:165496;   KEGG:C14790
 xref_mesh: MESH:D015057
 xref: PMID:23706116;   PMID:24735928;   Reaxys:386133;   Wikipedia:1-Naphthylamine


show annotations for term's descendants           Sort by:
1-naphthylamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO 1-Naphthylamine binds to and results in increased activity of AHR protein CTD PMID:11790108 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO 1-Naphthylamine results in decreased expression of CYP17A1 mRNA CTD PMID:31100596 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression ISO 1-Naphthylamine results in increased expression of CYP19A1 mRNA CTD PMID:31100596 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Fam83b family with sequence similarity 83, member B affects response to substance ISO FAM83B gene SNP affects the susceptibility to 1-Naphthylamine CTD PMID:25622337 NCBI chr 8:77,287,351...77,363,795
Ensembl chr 8:77,287,351...77,363,795 		JBrowse link
G Npas3 neuronal PAS domain protein 3 affects response to substance ISO NPAS3 gene SNP affects the susceptibility to 1-Naphthylamine CTD PMID:25622337 NCBI chr 6:70,702,773...71,527,928
Ensembl chr 6:70,703,170...71,524,884 		JBrowse link
G Tmem132d transmembrane protein 132D affects response to substance ISO TMEM132D gene SNP affects the susceptibility to 1-Naphthylamine CTD PMID:25622337 NCBI chr12:28,270,039...28,917,324
Ensembl chr12:28,270,712...28,915,374 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 decreases activity ISO 1-Naphthylamine results in decreased activity of UGT1A9 protein CTD PMID:14744740 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      biological role 19785
        biochemical role 19496
          metabolite 19484
            xenobiotic metabolite 15429
              human xenobiotic metabolite 14795
                1-naphthylamine 7
                  N-(1-naphthyl)carboxamide + 0
                  N-hydroxynaphthalen-1-amine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    main group molecular entity 19759
                      s-block molecular entity 19628
                        hydrogen molecular entity 19614
                          hydrides 19087
                            inorganic hydride 18091
                              pnictogen hydride 18080
                                nitrogen hydride 17987
                                  azane 17796
                                    ammonia 17795
                                      organic amino compound 17795
                                        primary amino compound 9297
                                          primary amine 6317
                                            primary arylamine 3643
                                              naphthylamine 99
                                                1-naphthylamine 7
                                                  N-(1-naphthyl)carboxamide + 0
                                                  N-hydroxynaphthalen-1-amine 0
paths to the root