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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:platelet glycoprotein-IIb/IIIa receptor antagonist
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Accession:CHEBI:50433 term browser browse the term
Definition:Antagonist of platelet surface glycoprotein-IIb/IIIa which has a key role in hemostasis and thrombosis such as platelet adhesion and aggregation.
Synonyms:related_synonym: GPIIb/IIIa antagonist;   GPIIb/IIIa antagonists;   fibrinogen receptor antagonist;   fibrinogen receptor antagonists;   glycoprotein-IIb/IIIa receptor antagonist;   glycoprotein-IIb/IIIa receptor antagonists;   platelet glycoprotein-IIb/IIIa receptor antagonists
 xref: Wikipedia:Glycoprotein_IIb/IIIa_inhibitors



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prasugrel hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2RY12 purinergic receptor P2Y12 multiple interactions ISO Prasugrel Hydrochloride binds to and results in decreased activity of P2RY12 protein CTD PMID:17681285 NCBI chr 3:151,336,843...151,384,753
Ensembl chr 3:151,336,843...151,384,753
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 24838
    role 24759
      biological role 24728
        pharmacological role 21260
          antagonist 17323
            platelet glycoprotein-IIb/IIIa receptor antagonist 1
              fradafiban + 0
              lefradafiban 0
              prasugrel 0
              prasugrel hydrochloride 1
              tirofiban + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 24838
    role 24759
      application 23908
        pharmaceutical 23504
          drug 23504
            hematologic agent 4445
              platelet aggregation inhibitor 3409
                platelet glycoprotein-IIb/IIIa receptor antagonist 1
                  fradafiban + 0
                  lefradafiban 0
                  prasugrel 0
                  prasugrel hydrochloride 1
                  tirofiban + 0
paths to the root