CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: acid-base indicator
Accession: CHEBI:50407
browse the term
Definition: An acid or base which exhibits a colour change on neutralization by the basic or acidic titrant at or near the equivalence point of a titration.
Synonyms: related_synonym: Saeure-Base-Indikator; Saeure-Base-Indikatoren; indicador acido-base; indicateur acide-base
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Ache
acetylcholinesterase
affects binding decreases activity
ISO
Aminacrine binds to ACHE protein Aminacrine results in decreased activity of ACHE protein
CTD
PMID:31176713 PMID:33844597
NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
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Bax
BCL2 associated X, apoptosis regulator
increases response to substance
ISO
BAX protein results in increased susceptibility to Aminacrine
CTD
PMID:16177561
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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H2ax
H2A.X variant histone
decreases phosphorylation multiple interactions
ISO
Aminacrine results in decreased phosphorylation of H2AX protein [Aminacrine results in decreased phosphorylation of H2AX protein] inhibits the reaction [Camptothecin results in increased activity of and affects the localization of MDC1 protein]
CTD
PMID:26928355
NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
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Hif1a
hypoxia inducible factor 1 subunit alpha
increases activity
ISO
Aminacrine results in increased activity of HIF1A protein
CTD
PMID:19502547
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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Mdc1
mediator of DNA damage checkpoint 1
multiple interactions
ISO
[Aminacrine results in decreased phosphorylation of H2AX protein] inhibits the reaction [Camptothecin results in increased activity of and affects the localization of MDC1 protein]; Aminacrine inhibits the reaction [Camptothecin results in increased activity of and affects the localization of MDC1 protein]
CTD
PMID:26928355
NCBI chr20:2,893,693...2,912,394
Ensembl chr20:2,895,505...2,910,240
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Nr1h4
nuclear receptor subfamily 1, group H, member 4
multiple interactions
ISO
Aminacrine inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]
CTD
PMID:25257666
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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Slc22a2
solute carrier family 22 member 2
multiple interactions
ISO
Aminacrine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
CTD
PMID:21599003
NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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Tp53
tumor protein p53
multiple interactions affects activity
ISO
Aminacrine results in increased stability of and results in increased activity of TP53 protein Aminacrine analog affects the activity of TP53 protein
CTD
PMID:16177561 PMID:35435491
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions
ISO
Bromcresol Purple binds to and results in decreased activity of NR1I2 protein
CTD
PMID:20869355
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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Iyd
iodotyrosine deiodinase
multiple interactions
ISO
Bromphenol Blue inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine]
CTD
PMID:33352258
NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions
ISO
Bromthymol Blue binds to and results in increased activity of NR1I2 protein
CTD
PMID:20869355
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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Nr1i3
nuclear receptor subfamily 1, group I, member 3
multiple interactions
ISO
Bromthymol Blue binds to and results in decreased activity of NR1I3 protein alternative form
CTD
PMID:20869355
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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Ache
acetylcholinesterase
decreases activity
ISO
Methylene Blue results in decreased activity of ACHE protein
CTD
PMID:33844597
NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
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Atp1a2
ATPase Na+/K+ transporting subunit alpha 2
multiple interactions
ISO
Methylene Blue inhibits the reaction [Sodium Cyanide results in increased phosphorylation of ATP1A2 protein]
CTD
PMID:31173149
NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions
EXP
Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX protein]
CTD
PMID:31428839
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2
BCL2, apoptosis regulator
multiple interactions
EXP
Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]
CTD
PMID:31428839
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Cacna1c
calcium voltage-gated channel subunit alpha1 C
multiple interactions
ISO
Methylene Blue inhibits the reaction [Sodium Cyanide results in increased phosphorylation of CACNA1C protein]
CTD
PMID:31173149
NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
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Calca
calcitonin-related polypeptide alpha
multiple interactions
EXP
Methylene Blue inhibits the reaction [Nitroglycerin results in increased expression of CALCA mRNA]
CTD
PMID:11919648
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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G6pd
glucose-6-phosphate dehydrogenase
increases activity
ISO
Methylene Blue results in increased activity of G6PD protein
CTD
PMID:1901343
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
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Gclc
glutamate-cysteine ligase, catalytic subunit
multiple interactions increases expression
ISO
[Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of GCLC mRNA; NFE2L2 gene mutant form inhibits the reaction [Methylene Blue results in increased expression of GCLC mRNA]
CTD
PMID:24556215
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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Gclm
glutamate cysteine ligase, modifier subunit
multiple interactions
ISO
[Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of GCLM mRNA
CTD
PMID:24556215
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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Gfap
glial fibrillary acidic protein
multiple interactions
ISO
Methylene Blue inhibits the reaction [MAPT protein mutant form results in increased expression of GFAP mRNA]; Methylene Blue inhibits the reaction [MAPT protein mutant form results in increased expression of GFAP protein]
CTD
PMID:24556215
NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
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Glrx
glutaredoxin
multiple interactions
ISO
[Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of GLRX mRNA
CTD
PMID:24556215
NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
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Glrx2
glutaredoxin 2
multiple interactions
ISO
[Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of GLRX2 mRNA
CTD
PMID:24556215
NCBI chr13:55,481,875...55,504,737
Ensembl chr13:55,482,694...55,492,831
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Gnrh1
gonadotropin releasing hormone 1
multiple interactions
EXP
Methylene Blue inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]
CTD
PMID:17290048
NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581 Ensembl chr15:41,972,905...41,973,581
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Gstp1
glutathione S-transferase pi 1
multiple interactions
ISO
Methylene Blue inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]
CTD
PMID:23769903
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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Hmox1
heme oxygenase 1
multiple interactions increases expression
ISO EXP
[Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of HMOX1 mRNA; NFE2L2 gene mutant form inhibits the reaction [Methylene Blue results in increased expression of HMOX1 mRNA] Methylene Blue results in increased expression of HMOX1 protein
CTD
PMID:24556215 PMID:25943564
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Icam1
intercellular adhesion molecule 1
multiple interactions
EXP
Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]
CTD
PMID:31428839
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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Il17a
interleukin 17A
multiple interactions
EXP
Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL17A protein]
CTD
PMID:31428839
NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
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Il6
interleukin 6
multiple interactions
EXP
Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]
CTD
PMID:31428839
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Iyd
iodotyrosine deiodinase
multiple interactions
ISO
Methylene Blue inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine]
CTD
PMID:33352258
NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
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Maob
monoamine oxidase B
multiple interactions decreases activity
ISO
Methylene Blue inhibits the reaction [MAOB protein results in increased oxidation of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] Methylene Blue results in decreased activity of MAOB protein
CTD
PMID:21554916
NCBI chr X:5,907,327...6,010,996
Ensembl chr X:5,907,266...6,011,003
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Mapt
microtubule-associated protein tau
decreases expression multiple interactions decreases phosphorylation increases expression
ISO
Methylene Blue results in decreased expression of MAPT protein [Methylene Blue co-treated with MAPT protein mutant form] affects the localization of NFE2L2 protein; [Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of GCLC mRNA; [Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of GCLM mRNA; [Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of GLRX mRNA; [Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of GLRX2 mRNA; [Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of HMOX1 mRNA; [Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of NFE2L2 mRNA; [Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of NQO1 mRNA; [Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of PRDX6 mRNA; [Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of TXN2 mRNA; [Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of TXNRD2 mRNA; Methylene Blue affects the reaction [MAPT protein mutant form affects the expression of TXNRD1 mRNA]; Methylene Blue affects the reaction [MAPT protein mutant form results in increased expression of TXN mRNA]; Methylene Blue co-treated with [MAPT protein mutant form results in increased expression of NOS2 mRNA]; Methylene Blue inhibits the reaction [MAPT protein mutant form results in increased expression of GFAP mRNA]; Methylene Blue inhibits the reaction [MAPT protein mutant form results in increased expression of GFAP protein] Methylene Blue results in decreased phosphorylation of MAPT protein modified form Methylene Blue results in increased expression of MAPT mRNA
CTD
PMID:16930453 PMID:24556215
NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
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Mpo
myeloperoxidase
multiple interactions
EXP
Methylene Blue inhibits the reaction [Paraquat results in increased expression of MPO protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]
CTD
PMID:25943564 PMID:31428839
NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Nfe2l2
NFE2 like bZIP transcription factor 2
multiple interactions
ISO EXP
[Methylene Blue co-treated with MAPT protein mutant form] affects the localization of NFE2L2 protein; [Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of NFE2L2 mRNA; NFE2L2 gene mutant form inhibits the reaction [Methylene Blue results in increased expression of GCLC mRNA]; NFE2L2 gene mutant form inhibits the reaction [Methylene Blue results in increased expression of HMOX1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Methylene Blue results in increased expression of NQO1 mRNA] Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFE2L2 mRNA]
CTD
PMID:24556215 PMID:31428839
NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
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Nos2
nitric oxide synthase 2
multiple interactions
ISO EXP
Methylene Blue co-treated with [MAPT protein mutant form results in increased expression of NOS2 mRNA] Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of NOS2 protein]
CTD
PMID:24556215 PMID:31428839
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Nqo1
NAD(P)H quinone dehydrogenase 1
multiple interactions increases expression
ISO
[Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of NQO1 mRNA; NFE2L2 gene mutant form inhibits the reaction [Methylene Blue results in increased expression of NQO1 mRNA]
CTD
PMID:24556215
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Pgd
phosphogluconate dehydrogenase
increases activity
ISO
Methylene Blue results in increased activity of PGD protein
CTD
PMID:1901343
NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778
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Prdx6
peroxiredoxin 6
multiple interactions
ISO
[Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of PRDX6 mRNA
CTD
PMID:24556215
NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
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Prkce
protein kinase C, epsilon
multiple interactions
ISO
Methylene Blue inhibits the reaction [Sodium Cyanide results in increased activity of and affects the localization of PRKCE protein]
CTD
PMID:31173149
NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
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Slc2a1
solute carrier family 2 member 1
multiple interactions increases activity
ISO
oxophenylarsine inhibits the reaction [Methylene Blue results in increased activity of SLC2A1 protein]
CTD
PMID:19686715
NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
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Tnf
tumor necrosis factor
multiple interactions
EXP
Methylene Blue inhibits the reaction [Nitroglycerin results in decreased expression of TNF protein]
CTD
PMID:11744139
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tp53
tumor protein p53
affects activity
ISO
Methylene Blue affects the activity of TP53 protein
CTD
PMID:35435491
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
G
Txn1
thioredoxin 1
multiple interactions
ISO
Methylene Blue affects the reaction [MAPT protein mutant form results in increased expression of TXN mRNA]
CTD
PMID:24556215
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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Txn2
thioredoxin 2
multiple interactions
ISO
[Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of TXN2 mRNA
CTD
PMID:24556215
NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359
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Txnrd1
thioredoxin reductase 1
multiple interactions
ISO
Methylene Blue affects the reaction [MAPT protein mutant form affects the expression of TXNRD1 mRNA]
CTD
PMID:24556215
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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Txnrd2
thioredoxin reductase 2
multiple interactions
ISO
[Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of TXNRD2 mRNA
CTD
PMID:24556215
NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
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Abcc2
ATP binding cassette subfamily C member 2
affects export
EXP
ABCC2 protein affects the export of Phenolsulfonphthalein
CTD
PMID:15618741
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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Actbl2
actin, beta-like 2
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of ACTBL2 protein
CTD
PMID:31629898
NCBI chr 2:42,858,020...42,860,767
Ensembl chr 2:42,858,020...42,860,767
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Afap1
actin filament associated protein 1
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of AFAP1 protein
CTD
PMID:31629898
NCBI chr14:74,743,322...74,856,295
Ensembl chr14:74,743,320...74,856,263
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Akt1
AKT serine/threonine kinase 1
multiple interactions
ISO
Phenolsulfonphthalein results in decreased phosphorylation of and results in decreased activity of AKT1 protein
CTD
PMID:17203231
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Ankrd17
ankyrin repeat domain 17
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of ANKRD17 protein
CTD
PMID:31629898
NCBI chr14:17,723,239...17,862,625
Ensembl chr14:17,721,932...17,862,617
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Anxa11
annexin A11
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of ANXA11 protein
CTD
PMID:31629898
NCBI chr16:1,412,373...1,457,814
Ensembl chr16:1,410,756...1,457,797
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Anxa3
annexin A3
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of ANXA3 protein
CTD
PMID:31629898
NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
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Arcn1
archain 1
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of ARCN1 protein
CTD
PMID:31629898
NCBI chr 8:45,057,617...45,082,224
Ensembl chr 8:45,057,619...45,082,247
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Asap1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of ASAP1 protein
CTD
PMID:31629898
NCBI chr 7:95,786,130...96,093,111
Ensembl chr 7:95,787,818...96,092,754
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Bcl2l1
Bcl2-like 1
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of BCL2L1 protein
CTD
PMID:31629898
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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Cdh1
cadherin 1
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of CDH1 protein; [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in decreased expression of CDH1 protein
CTD
PMID:31629898
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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Cdh2
cadherin 2
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of CDH2 protein
CTD
PMID:31629898
NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
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Cfl2
cofilin 2
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of CFL2 protein
CTD
PMID:31629898
NCBI chr 6:72,355,664...72,359,709
Ensembl chr 6:72,355,664...72,359,674
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Ckap5
cytoskeleton associated protein 5
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of CKAP5 protein
CTD
PMID:31629898
NCBI chr 3:77,491,195...77,593,300
Ensembl chr 3:77,491,276...77,593,264
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Ctcf
CCCTC-binding factor
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of CTCF protein
CTD
PMID:31629898
NCBI chr19:33,521,726...33,571,124
Ensembl chr19:33,529,319...33,571,123
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Ctnnb1
catenin beta 1
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of CTNNB1 protein
CTD
PMID:31629898
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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Ctnnbl1
catenin, beta like 1
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of CTNNBL1 protein
CTD
PMID:31629898
NCBI chr 3:146,387,940...146,548,987
Ensembl chr 3:146,387,889...146,548,987
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Ctnnd1
catenin delta 1
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of CTNND1 protein
CTD
PMID:31629898
NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516
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Dnm1
dynamin 1
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of DNM1 protein
CTD
PMID:31629898
NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538
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Dnm2
dynamin 2
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of DNM2 protein
CTD
PMID:31629898
NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157
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Dsg2
desmoglein 2
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of DSG2 protein
CTD
PMID:31629898
NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156
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Dync1li1
dynein cytoplasmic 1 light intermediate chain 1
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of DYNC1LI1 protein
CTD
PMID:31629898
NCBI chr 8:114,376,649...114,410,297
Ensembl chr 8:114,376,662...114,410,934
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Dynlt1
dynein light chain Tctex-type 1
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of DYNLT1 protein
CTD
PMID:31629898
NCBI chr 1:46,887,017...46,893,956
Ensembl chr 1:46,887,017...46,893,881
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Eif2b4
eukaryotic translation initiation factor 2B subunit delta
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of EIF2B4 protein
CTD
PMID:31629898
NCBI chr 6:25,183,177...25,188,832
Ensembl chr 6:25,183,186...25,188,829
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Eif4a3
eukaryotic translation initiation factor 4A3
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of EIF4A3 protein
CTD
PMID:31629898
NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057
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Esrrg
estrogen-related receptor gamma
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] inhibits the reaction [ESRRG protein binds to GJA1 protein binds to SNAI1 protein]; [Phenolsulfonphthalein deficiency co-treated with bisphenol A] inhibits the reaction [ESRRG protein binds to GJA1 protein binds to SNAI1 protein]; [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of ESRRG protein
CTD
PMID:31629898
NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397
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G3bp1
G3BP stress granule assembly factor 1
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of G3BP1 protein
CTD
PMID:31629898
NCBI chr10:39,586,864...39,620,268
Ensembl chr10:39,586,864...39,620,268
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Gdi2
GDP dissociation inhibitor 2
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of GDI2 protein
CTD
PMID:31629898
NCBI chr17:66,649,616...66,676,299
Ensembl chr17:66,649,619...66,676,366
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Gja1
gap junction protein, alpha 1
multiple interactions
ISO
[Phenolsulfonphthalein co-treated with bisphenol A deficiency] results in increased expression of GJA1 protein; [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] inhibits the reaction [ESRRG protein binds to GJA1 protein binds to SNAI1 protein]; [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in decreased expression of GJA1 protein; [Phenolsulfonphthalein deficiency co-treated with bisphenol A] inhibits the reaction [ESRRG protein binds to GJA1 protein binds to SNAI1 protein]; [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of GJA1 protein
CTD
PMID:31629898
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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Gna13
G protein subunit alpha 13
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of GNA13 protein
CTD
PMID:31629898
NCBI chr10:94,337,939...94,370,774
Ensembl chr10:94,337,725...94,370,774
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Gnai1
G protein subunit alpha i1
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of GNAI1 protein
CTD
PMID:31629898
NCBI chr 4:16,813,941...16,898,111
Ensembl chr 4:16,814,001...16,896,417
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H2ac12
H2A clustered histone 12
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of H2AC12 protein
CTD
PMID:31629898
NCBI chr17:42,486,315...42,486,880
Ensembl chr17:42,486,415...42,486,941
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Iqgap2
IQ motif containing GTPase activating protein 2
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of IQGAP2 protein
CTD
PMID:31629898
NCBI chr 2:26,894,836...27,170,270
Ensembl chr 2:26,894,825...27,170,279
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Kif5b
kinesin family member 5B
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of KIF5B protein
CTD
PMID:31629898
NCBI chr17:51,489,873...51,527,508
Ensembl chr17:51,489,944...51,527,508
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Kpna3
karyopherin subunit alpha 3
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of KPNA3 protein
CTD
PMID:31629898
NCBI chr15:35,536,310...35,610,066
Ensembl chr15:35,536,316...35,610,419
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Krt31
keratin 31
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of KRT31 protein
CTD
PMID:31629898
NCBI chr10:84,979,130...84,982,832
Ensembl chr10:84,979,352...84,982,832
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Krt34
keratin 34
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of KRT34 protein
CTD
PMID:31629898
NCBI chr10:84,970,351...84,974,040
Ensembl chr10:84,970,017...84,974,040
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Krt84
keratin 84
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of KRT84 protein
CTD
PMID:31629898
NCBI chr 7:132,649,064...132,656,885
Ensembl chr 7:132,649,061...132,656,874
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Lsg1
large 60S subunit nuclear export GTPase 1
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of LSG1 protein
CTD
PMID:31629898
NCBI chr11:70,132,919...70,168,526
Ensembl chr11:70,143,847...70,168,518
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Mpo
myeloperoxidase
multiple interactions increases oxidation
ISO
[MPO protein results in increased oxidation of Phenolsulfonphthalein] which results in decreased abundance of Glutathione; [MPO protein results in increased oxidation of Phenolsulfonphthalein] which results in increased abundance of Glutathione Disulfide; MPO protein promotes the reaction [Phenolsulfonphthalein binds to Halogens]; Phenolsulfonphthalein promotes the reaction [MPO protein promotes the reaction [chlorodimedone binds to Chlorine]]
CTD
PMID:31288001
NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Myh1
myosin heavy chain 1
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of MYH1 protein
CTD
PMID:31629898
NCBI chr10:51,885,913...51,909,699
Ensembl chr10:51,885,913...51,946,295
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Myo10
myosin X
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of MYO10 protein
CTD
PMID:31629898
NCBI chr 2:76,100,962...76,304,164
Ensembl chr 2:76,100,987...76,303,030
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Myo5c
myosin VC
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of MYO5C protein
CTD
PMID:31629898
NCBI chr 8:75,989,497...76,066,485
Ensembl chr 8:75,989,528...76,066,483
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Nemf
nuclear export mediator factor
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of NEMF protein
CTD
PMID:31629898
NCBI chr 6:87,791,650...87,835,826
Ensembl chr 6:87,791,656...87,835,841
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Nfib
nuclear factor I/B
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of NFIB protein
CTD
PMID:31629898
NCBI chr 5:96,759,208...96,973,092
Ensembl chr 5:96,764,653...96,975,479
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Nifk
nucleolar protein interacting with the FHA domain of MKI67
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of NIFK protein
CTD
PMID:31629898
NCBI chr13:29,393,303...29,403,387
Ensembl chr13:29,393,286...29,405,896
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Noc3l
NOC3-like DNA replication regulator
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of NOC3L protein
CTD
PMID:31629898
NCBI chr 1:236,556,037...236,585,372
Ensembl chr 1:236,556,789...236,585,318
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Pcbp1
poly(rC) binding protein 1
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of PCBP1 protein
CTD
PMID:31629898
NCBI chr 4:118,972,698...118,974,722
Ensembl chr 4:118,972,661...118,976,500
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Pgr
progesterone receptor
increases expression
ISO
Phenolsulfonphthalein results in increased expression of PGR protein
CTD
PMID:3458212
NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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Phf14
PHD finger protein 14
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of PHF14 protein
CTD
PMID:31629898
NCBI chr 4:40,009,691...40,195,870
Ensembl chr 4:40,009,264...40,195,885
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Phf5a
PHD finger protein 5A
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of PHF5A protein
CTD
PMID:31629898
NCBI chr 7:113,378,469...113,385,035
Ensembl chr 7:113,378,471...113,385,460
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Pou5f1
POU class 5 homeobox 1
increases expression
ISO
Phenolsulfonphthalein results in increased expression of POU5F1 mRNA
CTD
PMID:22132214
NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
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Rab12
RAB12, member RAS oncogene family
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of RAB12 protein
CTD
PMID:31629898
NCBI chr 9:106,480,301...106,506,895
Ensembl chr 9:106,480,301...106,506,910
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Rab14
RAB14, member RAS oncogene family
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of RAB14 protein
CTD
PMID:31629898
NCBI chr 3:18,501,953...18,523,253
Ensembl chr 3:18,501,963...18,523,172
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Rab24
RAB24, member RAS oncogene family
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of RAB24 protein
CTD
PMID:31629898
NCBI chr17:9,308,363...9,310,568
Ensembl chr17:9,308,525...9,310,553
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Rab27a
RAB27A, member RAS oncogene family
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of RAB27A protein
CTD
PMID:31629898
NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829
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Rab27b
RAB27B, member RAS oncogene family
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of RAB27B protein
CTD
PMID:31629898
NCBI chr18:63,597,554...63,794,124
Ensembl chr18:63,600,937...63,757,180
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Rab5c
RAB5C, member RAS oncogene family
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of RAB5C protein
CTD
PMID:31629898
NCBI chr10:85,642,553...85,666,142
Ensembl chr10:85,642,809...85,666,103
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Rala
RAS like proto-oncogene A
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of RALA protein
CTD
PMID:31629898
NCBI chr17:47,092,139...47,145,192
Ensembl chr17:47,092,207...47,144,063
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Ralb
RAS like proto-oncogene B
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of RALB protein
CTD
PMID:31629898
NCBI chr13:30,588,036...30,624,199
Ensembl chr13:30,588,033...30,624,202
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Rap2b
RAP2B, member of RAS oncogene family
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of RAP2B protein
CTD
PMID:31629898
NCBI chr 2:145,599,714...145,600,265
Ensembl chr 2:145,599,116...145,603,069
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Rasip1
Ras interacting protein 1
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of RASIP1 protein
CTD
PMID:31629898
NCBI chr 1:96,097,078...96,109,564
Ensembl chr 1:96,091,074...96,109,562
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Rmdn3
regulator of microtubule dynamics 3
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of RMDN3 protein
CTD
PMID:31629898
NCBI chr 3:106,125,961...106,146,568
Ensembl chr 3:106,125,951...106,146,586
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Rras
RAS related
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of RRAS protein
CTD
PMID:31629898
NCBI chr 1:95,500,582...95,504,362
Ensembl chr 1:95,500,566...95,504,357
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Rrp9
ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of RRP9 protein
CTD
PMID:31629898
NCBI chr 8:107,116,411...107,126,123
Ensembl chr 8:107,117,471...107,126,123
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Scamp3
secretory carrier membrane protein 3
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of SCAMP3 protein
CTD
PMID:31629898
NCBI chr 2:174,583,124...174,588,984
Ensembl chr 2:174,570,653...174,588,985
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Snai1
snail family transcriptional repressor 1
multiple interactions
ISO
[Phenolsulfonphthalein co-treated with bisphenol A deficiency] results in increased expression of SNAI1 protein; [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] inhibits the reaction [ESRRG protein binds to GJA1 protein binds to SNAI1 protein]; [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in decreased expression of SNAI1 protein; [Phenolsulfonphthalein deficiency co-treated with bisphenol A] inhibits the reaction [ESRRG protein binds to GJA1 protein binds to SNAI1 protein]; [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of SNAI1 protein
CTD
PMID:31629898
NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
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Srp14
signal recognition particle 14
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of SRP14 protein
CTD
PMID:31629898
NCBI chr 3:105,442,184...105,445,875
Ensembl chr 3:105,442,198...105,445,859
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Ssbp1
single stranded DNA binding protein 1
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of SSBP1 protein
CTD
PMID:31629898
NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135
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Tbxa2r
thromboxane A2 receptor
multiple interactions
EXP
Phenolsulfonphthalein inhibits the reaction [Oleic Acid results in increased expression of TBXA2R mRNA]
CTD
PMID:11263294
NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176
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Tln1
talin 1
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of TLN1 protein
CTD
PMID:31629898
NCBI chr 5:57,787,670...57,817,900
Ensembl chr 5:57,787,943...57,817,900
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Tuba1a
tubulin, alpha 1A
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of TUBA1A protein
CTD
PMID:31629898
NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186
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Tubb3
tubulin, beta 3 class III
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of TUBB3 protein
CTD
PMID:31629898
NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
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Utp3
UTP3, small subunit processome component
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of UTP3 protein
CTD
PMID:31629898
NCBI chr14:19,515,716...19,517,370
Ensembl chr14:19,515,669...19,517,396
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Utp6
UTP6 small subunit processome component
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of UTP6 protein
CTD
PMID:31629898
NCBI chr10:64,897,321...64,928,105
Ensembl chr10:64,897,328...64,927,997
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Vim
vimentin
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of VIM protein
CTD
PMID:31629898
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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Ybx3
Y box binding protein 3
multiple interactions
ISO
[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of YBX3 protein
CTD
PMID:31629898
NCBI chr 4:165,129,747...165,153,101
Ensembl chr 4:165,129,758...165,153,161
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