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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1,9-dideoxyforskolin
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Accession:CHEBI:50295 term browser browse the term
Definition:A labdane diterpenoid that is the 1,9-dideoxy derivative of forskolin.
Synonyms:exact_synonym: (3R,4aS,5S,6S,6aS,10aS,10bR)-3-ethenyl-6-hydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-5-yl acetate
 related_synonym: (3R,4aS,5S,6S,6aS,10aS,10bR)-5-(acetyloxy)-3-ethenyldodecahydro-6-hydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho(2,1-b)pyran-1-one;   (3R-(3alpha,4abeta,5beta,6beta,6aalpha,10abeta,10balpha))-5-(acetyloxy)-3-ethenyldodecahydro-6-hydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho(2,1-b)pyran-1-one;   7beta-acetoxy-8,13-epoxy-6beta-hydroxylabd-14-en-11-one;   Formula=C22H34O5;   InChI=1S/C22H34O5/c1-8-20(5)12-14(24)16-21(6)11-9-10-19(3,4)17(21)15(25)18(26-13(2)23)22(16,7)27-20/h8,15-18,25H,1,9-12H2,2-7H3/t15-,16+,17-,18-,20-,21+,22-/m0/s1;   InChIKey=ZKZMDXUDDJYAIB-SUCLLAFCSA-N;   SMILES=[H][C@@]12[C@H](O)[C@H](OC(C)=O)[C@@]3(C)O[C@](C)(CC(=O)[C@]3([H])[C@@]1(C)CCCC2(C)C)C=C
 xref: Beilstein:5304980;   CAS:64657-18-7;   LIPID_MAPS_instance:LMPR0104030009
 xref_mesh: MESH:C047983
 xref: PMID:16749796;   PMID:19831022;   Reaxys:5304980



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1,9-dideoxyforskolin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity EXP 1,9-dideoxyforskolin results in decreased activity of ABCB1A protein CTD PMID:12202523 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B decreases activity EXP 1,9-dideoxyforskolin results in decreased activity of ABCB1B protein CTD PMID:12202523 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity EXP 1,9-dideoxyforskolin results in decreased activity of ABCB4 protein CTD PMID:12202523 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20039
    role 19990
      biological role 19989
        antimicrobial agent 17748
          antiviral agent 10469
            anti-HIV agent 1268
              forskolin 4
                1,9-dideoxyforskolin 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 20039
    subatomic particle 20037
      composite particle 20037
        hadron 20037
          baryon 20037
            nucleon 20037
              atomic nucleus 20037
                atom 20037
                  main group element atom 19938
                    p-block element atom 19938
                      carbon group element atom 19861
                        carbon atom 19852
                          organic molecular entity 19852
                            organic group 18932
                              organic divalent group 18916
                                organodiyl group 18916
                                  carbonyl group 18865
                                    carbonyl compound 18865
                                      ketone 17087
                                        oxyketone 8722
                                          alpha-oxyketone 8722
                                            alpha-hydroxy ketone 8722
                                              tertiary alpha-hydroxy ketone 8421
                                                forskolin 4
                                                  1,9-dideoxyforskolin 3
paths to the root