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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:hematologic agent
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Accession:CHEBI:50248 term browser browse the term
Definition:Drug that acts on blood and blood-forming organs and those that affect the hemostatic system.
Synonyms:related_synonym: hematologic agents


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acetylsalicylic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTGS1 prostaglandin-endoperoxide synthase 1 decreases activity EXP Aspirin results in decreased activity of PTGS1 protein alternative form CTD PMID:12242329 NCBI chr 9:60,195,118...60,216,847
Ensembl chr 9:60,195,124...60,216,819
JBrowse link
cilostazol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYC MYC proto-oncogene, bHLH transcription factor decreases expression EXP Cilostazol results in decreased expression of MYC mRNA CTD PMID:19545562 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309
JBrowse link
troglitazone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPS6KB1 ribosomal protein S6 kinase B1 multiple interactions EXP Troglitazone results in decreased activity of and results in decreased phosphorylation of RPS6KB1 protein CTD PMID:16825603 NCBI chr 9:34,387,084...34,590,603
Ensembl chr 9:34,387,091...34,425,292
JBrowse link
warfarin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2B6 cytochrome P450 2B11 increases hydroxylation EXP CYP2B6 protein results in increased hydroxylation of Warfarin CTD PMID:12637241 NCBI chr 1:112,817,561...112,833,294
Ensembl chr 1:112,816,502...112,833,293
JBrowse link
G CYP3A12 cytochrome P-450 3A12 increases hydroxylation EXP CYP3A12 protein results in increased hydroxylation of Warfarin CTD PMID:12637241

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 225
    role 225
      application 192
        pharmaceutical 189
          drug 189
            hematologic agent 5
              2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine 0
              2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine 0
              6-aminohexanoic acid + 0
              S-nitroso-L-cysteine + 0
              alginic acid 0
              anticoagulant + 5
              argipressin 0
              dermatan sulfate 0
              platelet aggregation inhibitor + 3
              poly(vinylpyrrolidone) + 0
              sodium alginate 0
              ticlopidine + 0
              tranexamic acid 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.