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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:maleate salt
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Accession:CHEBI:50221 term browser browse the term
Definition:Salts from maleic acid.
Synonyms:related_synonym: maleate salts



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4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline dimaleate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALCA calcitonin related polypeptide alpha decreases expression ISO CGS 12066B results in decreased expression of CALCA mRNA CTD PMID:14715155 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354
JBrowse link
G HTR1B 5-hydroxytryptamine receptor 1B affects binding ISO CGS 12066B binds to HTR1B protein CTD PMID:11888550 NCBI chr 6:77,460,924...77,463,491
Ensembl chr 6:77,460,924...77,463,491
JBrowse link
dizocilpine maleate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA3 adenosine A3 receptor multiple interactions ISO [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine binds to and results in increased activity of ADORA3 protein] which results in decreased susceptibility to Dizocilpine Maleate CTD PMID:12672554 NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633
JBrowse link
G AHCYL2 adenosylhomocysteinase like 2 increases expression ISO Dizocilpine Maleate results in increased expression of AHCYL2 protein CTD PMID:21297352 NCBI chr 7:129,225,030...129,430,211
Ensembl chr 7:129,225,030...129,430,211
JBrowse link
G AHR aryl hydrocarbon receptor multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 promoter]] CTD PMID:17973980 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Excitatory Amino Acid Agonists affects the localization of AIFM1 protein] CTD PMID:19201465 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879
JBrowse link
G ALDOC aldolase, fructose-bisphosphate C increases expression ISO Dizocilpine Maleate results in increased expression of ALDOC protein CTD PMID:21297352 NCBI chr17:28,573,120...28,576,895
Ensembl chr17:28,573,115...28,576,948
JBrowse link
G APP amyloid beta precursor protein multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Pentylenetetrazole results in increased expression of APP mRNA] CTD PMID:9720974 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
JBrowse link
G ARC activity regulated cytoskeleton associated protein multiple interactions ISO Dizocilpine Maleate inhibits the reaction [phosphinothricin results in increased expression of ARC mRNA] CTD PMID:30557575 NCBI chr 8:142,611,049...142,614,479
Ensembl chr 8:142,611,049...142,614,479
JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO Dizocilpine Maleate results in increased expression of BAX protein
Dizocilpine Maleate inhibits the reaction [Dextromethorphan results in increased expression of BAX protein]; Dizocilpine Maleate inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of BAX protein]
CTD PMID:19201465 PMID:19759125 PMID:25937004 PMID:28916251 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression
ISO Dizocilpine Maleate inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]
Dizocilpine Maleate results in decreased expression of BCL2 protein
Dizocilpine Maleate inhibits the reaction [decabromobiphenyl ether results in decreased expression of BCL2 protein]
CTD PMID:10859492 PMID:19879923 PMID:29151189 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Dextromethorphan results in decreased expression of BCL2L1 protein] CTD PMID:28916251 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BDNF brain derived neurotrophic factor affects expression
decreases expression
multiple interactions
ISO Dizocilpine Maleate affects the expression of BDNF mRNA
Dizocilpine Maleate results in decreased expression of BDNF mRNA
Dizocilpine Maleate inhibits the reaction [Pilocarpine results in increased expression of and results in increased localization of BDNF mRNA]; Pentobarbital inhibits the reaction [Dizocilpine Maleate affects the expression of BDNF mRNA]; Scopolamine inhibits the reaction [Dizocilpine Maleate affects the expression of BDNF mRNA]
CTD PMID:8247360 PMID:8405262 PMID:15282290 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G CAMK2A calcium/calmodulin dependent protein kinase II alpha multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Excitatory Amino Acid Agents promotes the reaction [CAMK2A protein binds to DRD3 protein]] CTD PMID:19217379 NCBI chr 5:150,219,491...150,290,130
Ensembl chr 5:150,219,491...150,290,093
JBrowse link
G CAMK4 calcium/calmodulin dependent protein kinase IV multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of CAMK4 protein] CTD PMID:17973980 NCBI chr 5:111,223,583...111,494,886
Ensembl chr 5:111,223,653...111,494,886
JBrowse link
G CASP3 caspase 3 increases expression
increases activity
multiple interactions
ISO Dizocilpine Maleate results in increased expression of CASP3 protein modified form
Dizocilpine Maleate results in increased activity of CASP3 protein
Dizocilpine Maleate inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Dizocilpine Maleate inhibits the reaction [D-Aspartic Acid results in increased activity of and results in increased cleavage of CASP3 protein]; Dizocilpine Maleate inhibits the reaction [Dextromethorphan results in increased cleavage of CASP3 protein]; Dizocilpine Maleate inhibits the reaction [Pilocarpine results in increased cleavage of CASP3 protein]
CTD PMID:19759125 PMID:21873648 PMID:22824136 PMID:25937004 PMID:28916251 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP9 caspase 9 increases activity ISO Dizocilpine Maleate results in increased activity of CASP9 protein CTD PMID:19759125 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase multiple interactions ISO [bastadin 12 co-treated with Ryanodine co-treated with Dizocilpine Maleate] inhibits the reaction [tetrabromobisphenol A results in decreased activity of CAT protein]; Dizocilpine Maleate inhibits the reaction [ammonium acetate results in decreased activity of CAT protein] CTD PMID:12885441 PMID:27718046 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCK cholecystokinin multiple interactions
decreases expression
ISO Clozapine inhibits the reaction [Dizocilpine Maleate results in decreased expression of CCK mRNA]; Clozapine inhibits the reaction [Dizocilpine Maleate results in decreased expression of CCK protein]
Dizocilpine Maleate results in decreased expression of CCK mRNA; Dizocilpine Maleate results in decreased expression of CCK protein
CTD PMID:16567023 NCBI chr 3:42,257,826...42,266,185
Ensembl chr 3:42,257,825...42,266,185
JBrowse link
G CHAT choline O-acetyltransferase multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Quinolinic Acid results in decreased activity of CHAT protein] CTD PMID:2976130 NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,667,942
JBrowse link
G CNR1 cannabinoid receptor 1 affects response to substance ISO CNR1 protein affects the susceptibility to Dizocilpine Maleate CTD PMID:17442049 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347
JBrowse link
G COL1A1 collagen type I alpha 1 chain increases expression
multiple interactions
EXP Dizocilpine Maleate results in increased expression of COL1A1 mRNA
Dizocilpine Maleate inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of COL1A1 mRNA]
CTD PMID:28987794 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G COL3A1 collagen type III alpha 1 chain multiple interactions EXP Dizocilpine Maleate inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of COL3A1 mRNA] CTD PMID:28987794 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746
JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions
decreases phosphorylation
increases phosphorylation
EXP
ISO
Dizocilpine Maleate inhibits the reaction [Sodium Glutamate results in increased expression of CREB1 mRNA]
Dizocilpine Maleate inhibits the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased phosphorylation of CREB1 protein]; Dizocilpine Maleate inhibits the reaction [Dopamine results in increased phosphorylation of CREB1 protein]; Dizocilpine Maleate inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CREB1 protein binds to CYP1A1 promoter]]
Dizocilpine Maleate results in decreased phosphorylation of CREB1 protein
Dizocilpine Maleate results in increased phosphorylation of CREB1 protein
Dizocilpine Maleate inhibits the reaction [Formaldehyde results in increased expression of CREB1 mRNA]
CTD PMID:14622123 PMID:15877933 PMID:17434604 PMID:17973980 PMID:31981724 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CTNNB1 catenin beta 1 decreases expression
multiple interactions
EXP Dizocilpine Maleate results in decreased expression of CTNNB1 mRNA
Famotidine inhibits the reaction [Dizocilpine Maleate results in decreased expression of CTNNB1 mRNA]; Olanzapine inhibits the reaction [Dizocilpine Maleate results in decreased expression of CTNNB1 mRNA]
CTD PMID:31563592 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Excitatory Amino Acid Agonists results in decreased activity of CXCL2 protein] CTD PMID:15914698 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 promoter]]; Dizocilpine Maleate inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CREB1 protein binds to CYP1A1 promoter]] CTD PMID:17973980 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP46A1 cytochrome P450 family 46 subfamily A member 1 multiple interactions EXP Dizocilpine Maleate inhibits the reaction [Sodium Glutamate results in increased expression of CYP46A1 mRNA]; Dizocilpine Maleate inhibits the reaction [Sodium Glutamate results in increased expression of CYP46A1 protein] CTD PMID:31981724 NCBI chr14:99,684,298...99,727,301
Ensembl chr14:99,684,298...99,727,301
JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 increases expression ISO Dizocilpine Maleate results in increased expression of DLG1 mRNA CTD PMID:11169168 NCBI chr 3:197,042,560...197,299,321
Ensembl chr 3:197,042,560...197,299,330
JBrowse link
G DLG4 discs large MAGUK scaffold protein 4 increases expression ISO Dizocilpine Maleate results in increased expression of DLG4 mRNA CTD PMID:11169168 NCBI chr17:7,187,187...7,220,050
Ensembl chr17:7,187,187...7,219,841
JBrowse link
G DNM1L dynamin 1 like multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Excitatory Amino Acid Agonists results in decreased expression of DNM1L protein] CTD PMID:25416777 NCBI chr12:32,679,301...32,745,650
Ensembl chr12:32,679,200...32,745,650
JBrowse link
G DRD1 dopamine receptor D1 multiple interactions ISO [[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Dizocilpine Maleate] co-treated with [1-hydroxy-3-amino-2-pyrrolidone results in increased activity of DRD1 protein]] results in increased susceptibility to Pilocarpine; Dizocilpine Maleate inhibits the reaction [Formaldehyde results in increased expression of DRD1 mRNA] CTD PMID:7906944 PMID:17434604 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
JBrowse link
G DRD2 dopamine receptor D2 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Formaldehyde results in increased expression of DRD2 mRNA] CTD PMID:17434604 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G DRD3 dopamine receptor D3 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Excitatory Amino Acid Agents promotes the reaction [CAMK2A protein binds to DRD3 protein]] CTD PMID:19217379 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
JBrowse link
G DUSP1 dual specificity phosphatase 1 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA] CTD PMID:11701771 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
JBrowse link
G DUSP6 dual specificity phosphatase 6 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA] CTD PMID:11701771 NCBI chr12:89,347,235...89,352,501
Ensembl chr12:89,347,235...89,352,501
JBrowse link
G EGR1 early growth response 1 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Zinc results in increased expression of EGR1 protein] CTD PMID:10428039 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein] CTD PMID:17303341 NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518
JBrowse link
G ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid] CTD PMID:19014389 NCBI chr 8:119,557,086...119,673,390
Ensembl chr 8:119,557,086...119,673,453
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of ERN1 protein] CTD PMID:17303341 NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819
JBrowse link
G FAAH fatty acid amide hydrolase decreases activity ISO Dizocilpine Maleate results in decreased activity of FAAH protein CTD PMID:17591864 NCBI chr 1:46,394,317...46,413,845
Ensembl chr 1:46,394,317...46,413,848
JBrowse link
G FGF2 fibroblast growth factor 2 increases expression ISO Dizocilpine Maleate results in increased expression of FGF2 mRNA CTD PMID:9832142 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
decreases expression
ISO Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of FOS protein]; Dizocilpine Maleate inhibits the reaction [Dextroamphetamine results in increased expression of FOS mRNA]; Dizocilpine Maleate inhibits the reaction [Dextromethorphan results in increased expression of FOS protein]; Dizocilpine Maleate inhibits the reaction [Pentylenetetrazole results in increased expression of FOS protein]; Dizocilpine Maleate inhibits the reaction [Pilocarpine results in increased expression of FOS mRNA]
[Morphine co-treated with Dizocilpine Maleate] inhibits the reaction [Naloxone results in increased expression of FOS protein]; Dizocilpine Maleate inhibits the reaction [[Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of FOS protein]; Dizocilpine Maleate inhibits the reaction [Haloperidol results in increased expression of FOS protein]
Dizocilpine Maleate results in increased expression of FOS mRNA
Dizocilpine Maleate results in decreased expression of FOS mRNA; Dizocilpine Maleate results in decreased expression of FOS protein
CTD PMID:7984056 PMID:8404677 PMID:11421588 PMID:12401322 PMID:12807422 More... NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit increases response to substance ISO FOSB protein modified form results in increased susceptibility to Dizocilpine Maleate CTD PMID:24067299 NCBI chr19:45,467,996...45,475,179
Ensembl chr19:45,467,995...45,475,179
JBrowse link
G GAD1 glutamate decarboxylase 1 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Oxygen deficiency results in decreased expression of GAD1 protein] CTD PMID:29107683 NCBI chr 2:170,813,210...170,861,151
Ensembl chr 2:170,813,213...170,861,151
JBrowse link
G GAL galanin and GMAP prepropeptide multiple interactions ISO Dizocilpine Maleate inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of GAL mRNA] CTD PMID:8730651 NCBI chr11:68,684,544...68,691,175
Ensembl chr11:68,683,779...68,691,175
JBrowse link
G GAP43 growth associated protein 43 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Kainic Acid results in increased expression of GAP43 mRNA] CTD PMID:8774942 NCBI chr 3:115,623,510...115,721,483
Ensembl chr 3:115,623,510...115,721,490
JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase increases expression ISO Dizocilpine Maleate results in increased expression of GAPDH protein CTD PMID:21297352 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374
JBrowse link
G GFAP glial fibrillary acidic protein multiple interactions ISO Dizocilpine Maleate inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein] CTD PMID:21863293 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937
JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of GRIA1 protein] CTD PMID:11801363 NCBI chr 5:153,489,615...153,813,869
Ensembl chr 5:153,489,615...153,813,869
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 affects binding
increases expression
multiple interactions
decreases activity
ISO
EXP
Dizocilpine Maleate binds to GRIN1 protein
Dizocilpine Maleate results in increased expression of GRIN1 mRNA
[GRIN1 protein co-treated with GRIN2A protein] results in increased susceptibility to Dizocilpine Maleate; [GRIN1 protein co-treated with GRIN2B protein] results in increased susceptibility to Dizocilpine Maleate; Dizocilpine Maleate inhibits the reaction [[GRIN1 protein co-treated with GRIN2A protein] results in increased susceptibility to Excitatory Amino Acid Agonists]
Dizocilpine Maleate results in decreased activity of GRIN1 protein
Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of GRIN1 protein]; Dizocilpine Maleate inhibits the reaction [Folic Acid deficiency results in increased expression of GRIN1 protein]; Dizocilpine Maleate promotes the reaction [GRIN1 protein binds to SRC protein]
CTD PMID:11249956 PMID:11801363 PMID:19224577 PMID:19788891 PMID:20406136 More... NCBI chr 9:137,139,154...137,168,756
Ensembl chr 9:137,138,346...137,168,756
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A multiple interactions
increases phosphorylation
EXP
ISO
[GRIN1 protein co-treated with GRIN2A protein] results in increased susceptibility to Dizocilpine Maleate; Dizocilpine Maleate inhibits the reaction [[GRIN1 protein co-treated with GRIN2A protein] results in increased susceptibility to Excitatory Amino Acid Agonists]
Dizocilpine Maleate inhibits the reaction [Folic Acid deficiency results in increased expression of GRIN2A protein]
Dizocilpine Maleate results in increased phosphorylation of GRIN2A protein
Dizocilpine Maleate inhibits the reaction [Formaldehyde results in increased expression of GRIN2A mRNA]
CTD PMID:11249956 PMID:17434604 PMID:19224577 PMID:20406136 NCBI chr16:9,753,404...10,182,908
Ensembl chr16:9,753,404...10,182,928
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B multiple interactions
decreases expression
EXP
ISO
[GRIN1 protein co-treated with GRIN2B protein] results in increased susceptibility to Dizocilpine Maleate
Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of GRIN2B protein]; Dizocilpine Maleate inhibits the reaction [Dextromethorphan results in increased expression of GRIN2B protein]
Dizocilpine Maleate results in decreased expression of GRIN2B mRNA
CTD PMID:11169168 PMID:11801363 PMID:19224577 PMID:28916251 NCBI chr12:13,537,337...13,982,134
Ensembl chr12:13,437,942...13,982,002
JBrowse link
G GRIN2C glutamate ionotropic receptor NMDA type subunit 2C decreases expression ISO Dizocilpine Maleate results in decreased expression of GRIN2C mRNA CTD PMID:11169168 NCBI chr17:74,842,023...74,861,532
Ensembl chr17:74,842,023...74,861,504
JBrowse link
G GSK3B glycogen synthase kinase 3 beta increases phosphorylation
increases expression
multiple interactions
ISO
EXP
Dizocilpine Maleate results in increased phosphorylation of GSK3B protein
Dizocilpine Maleate results in increased expression of GSK3B mRNA
3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Dizocilpine Maleate results in decreased phosphorylation of and results in increased activity of GSK3B protein]; Dizocilpine Maleate results in decreased phosphorylation of and results in increased activity of GSK3B protein; Famotidine inhibits the reaction [Dizocilpine Maleate results in decreased phosphorylation of and results in increased activity of GSK3B protein]; Famotidine inhibits the reaction [Dizocilpine Maleate results in increased expression of GSK3B mRNA]; Olanzapine inhibits the reaction [Dizocilpine Maleate results in increased expression of GSK3B mRNA]
CTD PMID:15877933 PMID:31563592 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A multiple interactions ISO Dizocilpine Maleate inhibits the reaction [[Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of HSPA1A protein] CTD PMID:16686654 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of HSPA5 protein] CTD PMID:17303341 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Ibotenic Acid results in increased expression of IL1B protein] CTD PMID:36925032 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Ibotenic Acid results in increased expression of IL6 protein] CTD PMID:36925032 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G INHBA inhibin subunit beta A multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Ibotenic Acid results in increased expression of INHBA protein] CTD PMID:36925032 NCBI chr 7:41,685,114...41,705,406
Ensembl chr 7:41,667,168...41,705,834
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Pilocarpine results in increased expression of JUN mRNA] CTD PMID:7984056 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Dizocilpine Maleate inhibits the reaction [[Oxidopamine co-treated with Levodopa] results in increased expression of JUNB mRNA]; Dizocilpine Maleate inhibits the reaction [Pilocarpine results in increased expression of JUNB mRNA] CTD PMID:7984056 PMID:9890435 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315
JBrowse link
G MAOA monoamine oxidase A multiple interactions ISO Dizocilpine Maleate inhibits the reaction [ammonium acetate results in increased activity of MAOA protein] CTD PMID:12885441 NCBI chr  X:43,655,006...43,746,817
Ensembl chr  X:43,654,907...43,746,817
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
decreases phosphorylation
EXP
ISO
Dizocilpine Maleate inhibits the reaction [Excitatory Amino Acid Agonists results in increased phosphorylation of MAPK1 protein]
Dizocilpine Maleate inhibits the reaction [Ammonium Chloride results in increased phosphorylation of MAPK1 protein]; Dizocilpine Maleate inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]
[Dizocilpine Maleate co-treated with 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline] inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein]; Dizocilpine Maleate affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK1 protein]; Dizocilpine Maleate inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] results in increased activity of and results in increased phosphorylation of MAPK1 protein]; Dizocilpine Maleate inhibits the reaction [Dronabinol results in increased activity of MAPK1 protein]; Dizocilpine Maleate inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Dizocilpine Maleate inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein]; Dizocilpine Maleate results in decreased phosphorylation of and results in decreased activity of MAPK1 protein
Dizocilpine Maleate results in decreased phosphorylation of MAPK1 protein
CTD PMID:11553284 PMID:11923223 PMID:12657697 PMID:15086530 PMID:15385614 More... NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
decreases phosphorylation
EXP
ISO
Dizocilpine Maleate inhibits the reaction [Excitatory Amino Acid Agonists results in increased phosphorylation of MAPK3 protein]
[Dizocilpine Maleate co-treated with 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline] inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]; Dizocilpine Maleate affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK3 protein]; Dizocilpine Maleate inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] results in increased activity of and results in increased phosphorylation of MAPK3 protein]; Dizocilpine Maleate inhibits the reaction [Dronabinol results in increased activity of MAPK3 protein]; Dizocilpine Maleate inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Dizocilpine Maleate inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK3 protein]; Dizocilpine Maleate results in decreased phosphorylation of and results in decreased activity of MAPK3 protein
Dizocilpine Maleate results in decreased phosphorylation of MAPK3 protein
Dizocilpine Maleate inhibits the reaction [Ammonium Chloride results in increased phosphorylation of MAPK3 protein]; Dizocilpine Maleate inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]
CTD PMID:11553284 PMID:11923223 PMID:12657697 PMID:15086530 PMID:15385614 More... NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPT microtubule associated protein tau multiple interactions EXP
ISO
Dizocilpine Maleate inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPT protein]
Dizocilpine Maleate inhibits the reaction [D-Aspartic Acid results in decreased expression of and affects the phosphorylation of MAPT protein]; Dizocilpine Maleate inhibits the reaction [D-Aspartic Acid results in decreased phosphorylation of MAPT protein]; Dizocilpine Maleate inhibits the reaction [D-Aspartic Acid results in increased cleavage of MAPT protein]
CTD PMID:21976409 PMID:30822420 NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334
JBrowse link
G MFN2 mitofusin 2 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Excitatory Amino Acid Agonists results in decreased expression of MFN2 protein] CTD PMID:25416777 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211
JBrowse link
G MMP1 matrix metallopeptidase 1 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Folic Acid deficiency results in decreased expression of MMP1 mRNA]; Dizocilpine Maleate inhibits the reaction [Homocysteine analog results in decreased expression of and results in decreased activity of MMP1 protein] CTD PMID:20406136 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Folic Acid deficiency results in decreased expression of MMP9 mRNA]; Dizocilpine Maleate inhibits the reaction [Homocysteine analog results in decreased expression of MMP9 protein] CTD PMID:20406136 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G NEFL neurofilament light chain multiple interactions ISO Dizocilpine Maleate inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFL protein]; Dizocilpine Maleate inhibits the reaction [N-Methylaspartate results in decreased expression of NEFL mRNA]; Dizocilpine Maleate inhibits the reaction [Rotenone results in decreased expression of NEFL mRNA] CTD PMID:21863293 PMID:31969611 NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721
JBrowse link
G NEFM neurofilament medium chain multiple interactions ISO Dizocilpine Maleate inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFM protein] CTD PMID:21863293 NCBI chr 8:24,913,761...24,919,093
Ensembl chr 8:24,913,758...24,919,098
JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Ammonium Chloride results in increased degradation of NFKBIA protein] CTD PMID:11923223 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
JBrowse link
G NME1 NME/NM23 nucleoside diphosphate kinase 1 increases expression ISO Dizocilpine Maleate results in increased expression of NME1 protein CTD PMID:21297352 NCBI chr17:51,153,559...51,162,168
Ensembl chr17:51,153,559...51,162,428
JBrowse link
G NOS1 nitric oxide synthase 1 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [decabromobiphenyl ether results in increased expression of NOS1 protein] CTD PMID:29151189 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Ammonium Chloride results in increased expression of NOS2 protein] CTD PMID:11923223 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NPS neuropeptide S decreases activity
multiple interactions
ISO NPS protein results in decreased activity of Dizocilpine Maleate
3-oxo-1,1-diphenyltetrahydrooxazolo(3,4-a)pyrazine-7-carboxylic acid 4-fluorobenzylamide inhibits the reaction [NPS protein results in decreased activity of Dizocilpine Maleate]
CTD PMID:21466221 NCBI chr10:127,549,309...127,553,540
Ensembl chr10:127,549,309...127,553,540
JBrowse link
G NSF N-ethylmaleimide sensitive factor, vesicle fusing ATPase increases expression ISO Dizocilpine Maleate results in increased expression of NSF protein CTD PMID:21297352 NCBI chr17:46,590,669...46,757,464
Ensembl chr17:46,590,669...46,757,679
JBrowse link
G OCLN occludin multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Excitatory Amino Acid Agonists results in decreased expression of OCLN protein] CTD PMID:26655082 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
JBrowse link
G OPRM1 opioid receptor mu 1 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCA protein]]; Dizocilpine Maleate inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCG protein]] CTD PMID:18652891 NCBI chr 6:154,010,496...154,246,867
Ensembl chr 6:154,010,496...154,246,867
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [ammonium acetate results in increased expression of PARP1 protein] CTD PMID:15147502 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PDE2A phosphodiesterase 2A multiple interactions ISO Dizocilpine Maleate inhibits the reaction [decabromobiphenyl ether results in increased expression of PDE2A mRNA] CTD PMID:29151189 NCBI chr11:72,576,141...72,674,422
Ensembl chr11:72,576,141...72,674,591
JBrowse link
G PDE5A phosphodiesterase 5A multiple interactions ISO Dizocilpine Maleate inhibits the reaction [decabromobiphenyl ether results in increased expression of PDE5A mRNA] CTD PMID:29151189 NCBI chr 4:119,494,403...119,628,804
Ensembl chr 4:119,494,397...119,628,804
JBrowse link
G PENK proenkephalin multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Amphetamine results in increased expression of PENK mRNA] CTD PMID:12850537 NCBI chr 8:56,440,957...56,446,641
Ensembl chr 8:56,436,674...56,446,671
JBrowse link
G POMC proopiomelanocortin multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Capsaicin results in increased secretion of POMC protein] CTD PMID:8925284 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
JBrowse link
G PRKCA protein kinase C alpha multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCA protein]] CTD PMID:18652891 NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743
JBrowse link
G PRKCG protein kinase C gamma multiple interactions
increases expression
ISO Dizocilpine Maleate inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCG protein]]
Dizocilpine Maleate results in increased expression of PRKCG mRNA
CTD PMID:11169168 PMID:18652891 NCBI chr19:53,881,094...53,907,652
Ensembl chr19:53,879,190...53,907,652
JBrowse link
G PRL prolactin decreases expression ISO Dizocilpine Maleate results in decreased expression of PRL protein CTD PMID:8404677 NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826
JBrowse link
G PRODH proline dehydrogenase 1 affects response to substance ISO PRODH protein affects the susceptibility to Dizocilpine Maleate CTD PMID:16234811 NCBI chr22:18,912,781...18,936,553
Ensembl chr22:18,912,777...18,936,553
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:15987631 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G PTN pleiotrophin multiple interactions ISO Dizocilpine Maleate promotes the reaction [Amphetamine results in increased expression of PTN mRNA] CTD PMID:15862925 NCBI chr 7:137,227,341...137,343,733
Ensembl chr 7:137,227,341...137,343,774
JBrowse link
G RAC1 Rac family small GTPase 1 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [bisphenol A results in increased expression of RAC1 protein]; Dizocilpine Maleate inhibits the reaction [Estradiol results in increased expression of RAC1 protein] CTD PMID:24231043 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967
JBrowse link
G RARA retinoic acid receptor alpha multiple interactions ISO Dizocilpine Maleate inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [Alitretinoin results in increased activity of RARA protein]] CTD PMID:15773917 NCBI chr17:40,309,180...40,357,643
Ensembl chr17:40,309,180...40,357,643
JBrowse link
G RHOA ras homolog family member A multiple interactions ISO Dizocilpine Maleate inhibits the reaction [bisphenol A results in decreased expression of RHOA protein]; Dizocilpine Maleate inhibits the reaction [Estradiol results in decreased expression of RHOA protein] CTD PMID:24231043 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998
JBrowse link
G SIRT1 sirtuin 1 multiple interactions EXP Dizocilpine Maleate inhibits the reaction [N-Methylaspartate results in decreased expression of and results in decreased activity of SIRT1 protein]; Dizocilpine Maleate inhibits the reaction [N-Methylaspartate results in decreased expression of SIRT1 mRNA] CTD PMID:31945382 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [ammonium acetate results in decreased activity of SOD2 protein] CTD PMID:12885441 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions
increases expression
increases activity
ISO Dizocilpine Maleate promotes the reaction [GRIN1 protein binds to SRC protein]; Dizocilpine Maleate results in increased phosphorylation of and results in increased activity of SRC protein
Dizocilpine Maleate results in increased expression of SRC mRNA; Dizocilpine Maleate results in increased expression of SRC protein
Dizocilpine Maleate results in increased activity of SRC protein
CTD PMID:11249956 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link
G SST somatostatin multiple interactions
decreases expression
ISO Clozapine inhibits the reaction [Dizocilpine Maleate results in decreased expression of SST mRNA]; Clozapine inhibits the reaction [Dizocilpine Maleate results in decreased expression of SST protein]
Dizocilpine Maleate results in decreased expression of SST mRNA; Dizocilpine Maleate results in decreased expression of SST protein
CTD PMID:16567023 NCBI chr 3:187,668,912...187,670,394
Ensembl chr 3:187,668,912...187,670,394
JBrowse link
G TAC1 tachykinin precursor 1 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased expression of TAC1 protein modified form] CTD PMID:11074153 NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472
JBrowse link
G TGFA transforming growth factor alpha multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Lipopolysaccharides results in increased secretion of TGFA] CTD PMID:15987631 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193
JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO Dizocilpine Maleate inhibits the reaction [Homocysteine analog results in increased expression of TIMP1 mRNA]; Dizocilpine Maleate inhibits the reaction [Homocysteine analog results in increased expression of TIMP1 protein] CTD PMID:20406136 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789
JBrowse link
G TJP1 tight junction protein 1 multiple interactions EXP Dizocilpine Maleate inhibits the reaction [N-Methylaspartate results in decreased expression of TJP1 mRNA]; Dizocilpine Maleate inhibits the reaction [N-Methylaspartate results in decreased expression of TJP1 protein] CTD PMID:35257817 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915
JBrowse link
G TPI1 triosephosphate isomerase 1 increases expression ISO Dizocilpine Maleate results in increased expression of TPI1 protein CTD PMID:21297352 NCBI chr12:6,867,420...6,870,948
Ensembl chr12:6,867,119...6,870,948
JBrowse link
G VIM vimentin multiple interactions ISO Dizocilpine Maleate inhibits the reaction [diphenylditelluride results in decreased phosphorylation of VIM protein] CTD PMID:21863293 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
JBrowse link
G XDH xanthine dehydrogenase multiple interactions ISO Dizocilpine Maleate inhibits the reaction [ammonium acetate affects the activity of XDH protein] CTD PMID:12885441 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26040
    chemical entity 26019
      molecular entity 25997
        ion 18748
          cation 18459
            salt 17479
              organic salt 3403
                maleate salt 104
                  (R,R)-asenapine maleate + 0
                  (S)-timolol maleate 0
                  (S,S)-asenapine maleate + 0
                  1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine maleate 0
                  2-\{[(2E)-3-iodoprop-2-en-1-yl](propyl)amino\}tetralin-7-ol maleate 0
                  4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline dimaleate 2
                  BGT226 0
                  N-methylquipazine dimaleate 0
                  O-(cyclohexanecarbonyl)lysergol maleate 0
                  Ro 25-6981 maleate 0
                  acetophenazine dimaleate 0
                  afatinib dimaleate 0
                  arterolane maleate 0
                  azatadine maleate 0
                  beta-aminoarteether maleate 0
                  brompheniramine maleate + 0
                  carbinoxamine maleate + 0
                  carphenazine maleate 0
                  dizocilpine maleate 102
                  domperidone maleate 0
                  enalapril maleate 0
                  ergometrine maleate 0
                  indacaterol maleate + 0
                  lisuride maleate 0
                  methiothepin maleate 0
                  paroxetine maleate 0
                  perphenazine maleate 0
                  pizotifen maleate 0
                  prochlorperazine maleate 0
                  proglumetacin dimaleate 0
                  rosiglitazone maleate 0
                  setiptiline maleate 0
                  tegaserod maleate 0
                  thiethylperazine maleate 0
                  trifluoperazine dimaleate 0
                  trimipramine maleate 0
                  tris maleate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26040
    subatomic particle 26015
      composite particle 26015
        hadron 26015
          baryon 26015
            nucleon 26015
              atomic nucleus 26015
                atom 26015
                  group 25882
                    polyatomic entity 25882
                      heteroatomic molecular entity 25533
                        salt 17479
                          organic salt 3403
                            maleate salt 104
                              (R,R)-asenapine maleate + 0
                              (S)-timolol maleate 0
                              (S,S)-asenapine maleate + 0
                              1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine maleate 0
                              2-\{[(2E)-3-iodoprop-2-en-1-yl](propyl)amino\}tetralin-7-ol maleate 0
                              4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline dimaleate 2
                              BGT226 0
                              N-methylquipazine dimaleate 0
                              O-(cyclohexanecarbonyl)lysergol maleate 0
                              Ro 25-6981 maleate 0
                              acetophenazine dimaleate 0
                              afatinib dimaleate 0
                              arterolane maleate 0
                              azatadine maleate 0
                              beta-aminoarteether maleate 0
                              brompheniramine maleate + 0
                              carbinoxamine maleate + 0
                              carphenazine maleate 0
                              dizocilpine maleate 102
                              domperidone maleate 0
                              enalapril maleate 0
                              ergometrine maleate 0
                              indacaterol maleate + 0
                              lisuride maleate 0
                              methiothepin maleate 0
                              paroxetine maleate 0
                              perphenazine maleate 0
                              pizotifen maleate 0
                              prochlorperazine maleate 0
                              proglumetacin dimaleate 0
                              rosiglitazone maleate 0
                              setiptiline maleate 0
                              tegaserod maleate 0
                              thiethylperazine maleate 0
                              trifluoperazine dimaleate 0
                              trimipramine maleate 0
                              tris maleate 0
paths to the root