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ONTOLOGY REPORT - ANNOTATIONS


Term:pizotifen
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Accession:CHEBI:50212 term browser browse the term
Definition:A benzocycloheptathiophene that is 9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophene 4-ylidene)-1-methylpiperidine which is joined from the 4 position to the 4 position of an N-methylpiperidine moiety by a double bond. It is a sedating antihistamine, with strong serotonin antagonist and weak antimuscarinic activity. It is generally used as the malate salt for the treatment of migraine and the prevention of headache attacks during cluster periods.
Synonyms:exact_synonym: 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine
 related_synonym: Formula=C19H21NS;   InChI=1S/C19H21NS/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18/h2-5,10,13H,6-9,11-12H2,1H3;   InChIKey=FIADGNVRKBPQEU-UHFFFAOYSA-N;   Pizotyline;   SMILES=CN1CCC(CC1)=C1c2ccccc2CCc2sccc12;   pizotifene;   pizotifeno;   pizotifenum
 xref: Beilstein:753534 "Beilstein";   CAS:15574-96-6 "ChemIDplus";   Drug_Central:2220 "DrugCentral";   KEGG:D05523;   LINCS:LSM-3695
 xref_mesh: MESH:D010918
 xref: Patent:BE636717;   Patent:US3272826;   Reaxys:753534 "Reaxys";   Wikipedia:Pizotifen
 cyclic_relationship: is_conjugate_base_of CHEBI:50318


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pizotifen term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      chemical role 19139
        base 16578
          piperidine 100
            pizotifen 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    main group molecular entity 19555
                      s-block molecular entity 19336
                        hydrogen molecular entity 19325
                          hydrides 18249
                            inorganic hydride 17113
                              pnictogen hydride 17071
                                nitrogen hydride 16891
                                  azane 16568
                                    ammonia 16565
                                      organic amino compound 16564
                                        secondary amino compound 6365
                                          secondary amine 1659
                                            piperidine 100
                                              pizotifen 1
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