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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:quinone imine
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Accession:CHEBI:50193 term browser browse the term
Definition:An imine formed formally from a quinone by replacement of one or more atoms of quinonoid oxygen by =NH or =NR.
Synonyms:related_synonym: quinone imines;   quinoneimine;   quinoneimines



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2,6-dichloroindophenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l1 Bcl2-like 1 multiple interactions ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in decreased expression of BCL2L1 mRNA CTD PMID:21034357 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CCL4 mRNA CTD PMID:21034357 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CDKN1A mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CDKN1A protein CTD PMID:21034357 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cntf ciliary neurotrophic factor multiple interactions ISO 2,6-Dichloroindophenol inhibits the reaction [Cadmium Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT1 protein]]; 2,6-Dichloroindophenol inhibits the reaction [Cadmium Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]] CTD PMID:19635391 NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877
JBrowse link
G Cryab crystallin, alpha B multiple interactions ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CRYAB mRNA CTD PMID:21034357 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CXCL10 mRNA CTD PMID:21034357 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of EGR1 mRNA CTD PMID:21034357 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Ephx2 epoxide hydrolase 2 multiple interactions ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of EPHX2 mRNA CTD PMID:21034357 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Faslg Fas ligand multiple interactions ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of FASLG mRNA CTD PMID:21034357 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of GADD45A mRNA CTD PMID:21034357 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of GDF15 mRNA CTD PMID:21034357 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of GSTM3 mRNA CTD PMID:21034357 NCBI chr 2:195,531,627...195,534,562
Ensembl chr 2:195,531,495...195,534,553
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HMOX1 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HMOX1 protein CTD PMID:21034357 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA1A mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA1A protein CTD PMID:21034357
G Hspa2 heat shock protein family A (Hsp70) member 2 multiple interactions ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA2 mRNA CTD PMID:21034357 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 multiple interactions ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA6 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA6 protein CTD PMID:21034357 NCBI chr13:83,271,340...83,275,267 JBrowse link
G Lta lymphotoxin alpha multiple interactions ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of LTA mRNA CTD PMID:21034357 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of NOS2 mRNA CTD PMID:21034357 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases response to substance
increases reduction
ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in decreased expression of BCL2L1 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CCL4 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CDKN1A mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CDKN1A protein; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CRYAB mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of CXCL10 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of EGR1 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of EPHX2 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of FASLG mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of GADD45A mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of GDF15 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of GSTM3 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HMOX1 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HMOX1 protein; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA1A mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA1A protein; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA2 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA6 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of HSPA6 protein; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of LTA mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of NOS2 mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of TNF mRNA; [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased phosphorylation of TP53 protein; Carbamazepine inhibits the reaction [NQO1 protein results in increased reduction of 2,6-Dichloroindophenol]; Diclofenac inhibits the reaction [NQO1 protein results in increased reduction of 2,6-Dichloroindophenol]; Dicumarol inhibits the reaction [NQO1 protein results in increased reduction of 2,6-Dichloroindophenol]; Mefenamic Acid inhibits the reaction [NQO1 protein results in increased reduction of 2,6-Dichloroindophenol]; NQO1 protein inhibits the reaction [2,6-Dichloroindophenol results in decreased abundance of Glutathione]; NQO1 protein polymorphism promotes the reaction [2,6-Dichloroindophenol results in decreased abundance of Glutathione]; Tacrine inhibits the reaction [NQO1 protein results in increased reduction of 2,6-Dichloroindophenol]
NQO1 protein polymorphism results in increased susceptibility to 2,6-Dichloroindophenol
CTD PMID:21034357 PMID:29281794 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 multiple interactions
increases reduction
ISO [NQO2 protein results in increased oxidation of 1-benzyl-1,4-dihydronicotinamide] which results in increased reduction of 2,6-Dichloroindophenol; [NQO2 protein results in increased oxidation of nicotinamide-beta-riboside] which results in increased reduction of 2,6-Dichloroindophenol; resveratrol inhibits the reaction [NQO2 protein results in increased reduction of 2,6-Dichloroindophenol]; Tacrine inhibits the reaction [NQO2 protein results in increased reduction of 2,6-Dichloroindophenol] CTD PMID:20399199 PMID:29281794 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO 2,6-Dichloroindophenol inhibits the reaction [Cadmium Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT1 protein]] CTD PMID:19635391 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO 2,6-Dichloroindophenol inhibits the reaction [Cadmium Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]] CTD PMID:19635391 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of TNF mRNA CTD PMID:21034357 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased phosphorylation of TP53 protein CTD PMID:21034357 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
Bandrowski's base term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B1 increases expression ISO Bandrowski's base results in increased expression of AKR1B1 mRNA CTD PMID:20566472 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Bandrowski's base results in increased expression of AKR1B10 mRNA CTD PMID:20566472 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases expression ISO Bandrowski's base results in increased expression of AKR1C1 mRNA CTD PMID:20566472 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO Bandrowski's base results in increased expression of AKR1C3 mRNA CTD PMID:20566472 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Cat catalase increases expression ISO Bandrowski's base results in increased expression of CAT mRNA CTD PMID:20566472 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 affects expression ISO Bandrowski's base affects the expression of CCL17 mRNA CTD PMID:18202158 NCBI chr19:10,202,317...10,203,768
Ensembl chr19:10,202,128...10,203,819
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 affects expression ISO Bandrowski's base affects the expression of CCL22 mRNA CTD PMID:18202158 NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 affects expression ISO Bandrowski's base affects the expression of CCL4 mRNA CTD PMID:18202158 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 affects expression
increases expression
ISO Bandrowski's base affects the expression of CCR7 mRNA
Bandrowski's base results in increased expression of CCR7 protein
CTD PMID:18202158 PMID:19665512 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
JBrowse link
G Cd80 Cd80 molecule increases expression ISO Bandrowski's base results in increased expression of CD80 protein CTD PMID:31958493 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
JBrowse link
G Cd86 CD86 molecule affects expression
increases expression
ISO Bandrowski's base affects the expression of CD86 mRNA
Bandrowski's base results in increased expression of CD86 protein
CTD PMID:18202158 PMID:19665512 PMID:21742781 PMID:31958493 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 affects expression ISO Bandrowski's base affects the expression of CXCR4 mRNA CTD PMID:18202158 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Fech ferrochelatase increases expression ISO Bandrowski's base results in increased expression of FECH mRNA CTD PMID:20566472 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO Bandrowski's base results in increased expression of FTL mRNA CTD PMID:20566472 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO Bandrowski's base results in increased expression of G6PD mRNA CTD PMID:20566472 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Bandrowski's base results in increased expression of GCLC mRNA CTD PMID:20566472 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Bandrowski's base results in increased expression of GCLM mRNA CTD PMID:20566472 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO Bandrowski's base results in increased expression of GPX3 mRNA CTD PMID:20566472 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO Bandrowski's base results in increased expression of GSR mRNA CTD PMID:20566472 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Bandrowski's base results in increased expression of HMOX1 mRNA CTD PMID:20566472 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression
affects expression
ISO Bandrowski's base results in increased expression of ICAM1 protein
Bandrowski's base affects the expression of ICAM1 mRNA
CTD PMID:18202158 PMID:21742781 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Bandrowski's base results in increased expression of MAFF mRNA CTD PMID:20566472 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO Bandrowski's base results in increased expression of MAFG mRNA CTD PMID:20566472 NCBI chr10:105,903,307...105,911,845
Ensembl chr10:105,903,237...105,912,026
JBrowse link
G Mafk MAF bZIP transcription factor K increases expression ISO Bandrowski's base results in increased expression of MAFK mRNA CTD PMID:20566472 NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048
Ensembl chr12:14,833,984...14,837,048
JBrowse link
G Me1 malic enzyme 1 increases expression ISO Bandrowski's base results in increased expression of ME1 mRNA CTD PMID:20566472 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO Bandrowski's base results in increased expression of MGST1 mRNA CTD PMID:20566472 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Mir155 microRNA 155 increases expression ISO Bandrowski's base results in increased expression of MIR155 mRNA CTD PMID:32939143 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir21 microRNA 21 decreases expression ISO Bandrowski's base results in decreased expression of MIR21 mRNA CTD PMID:32939143 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Bandrowski's base results in increased expression of NQO1 mRNA CTD PMID:20566472 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO Bandrowski's base results in increased expression of PGD mRNA CTD PMID:20566472 NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778
JBrowse link
G Ppia peptidylprolyl isomerase A affects expression ISO Bandrowski's base affects the expression of PPIA mRNA CTD PMID:18202158 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Prkcb protein kinase C, beta increases expression ISO Bandrowski's base results in increased expression of PRKCB protein CTD PMID:31958493 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO Bandrowski's base results in increased expression of PTGR1 mRNA CTD PMID:20566472 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO Bandrowski's base results in increased expression of SOD1 mRNA CTD PMID:20566472 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO Bandrowski's base results in increased expression of SOD2 mRNA CTD PMID:20566472 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sod3 superoxide dismutase 3 increases expression ISO Bandrowski's base results in increased expression of SOD3 mRNA CTD PMID:20566472 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Bandrowski's base results in increased expression of SRXN1 mRNA CTD PMID:20566472 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A affects expression ISO Bandrowski's base affects the expression of TNFRSF1A mRNA CTD PMID:18202158 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Txn2 thioredoxin 2 increases expression ISO Bandrowski's base results in increased expression of TXN2 mRNA CTD PMID:20566472 NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Bandrowski's base results in increased expression of TXNRD1 mRNA CTD PMID:20566472 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Txnrd2 thioredoxin reductase 2 increases expression ISO Bandrowski's base results in increased expression of TXNRD2 mRNA CTD PMID:20566472 NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression ISO Bandrowski's base results in increased expression of UGT1A6 mRNA CTD PMID:20566472 NCBI chr 9:88,747,229...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
N-acetyl-1,4-benzoquinone imine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions
ISO N-acetyl-4-benzoquinoneimine results in increased expression of ACTA2 mRNA; N-acetyl-4-benzoquinoneimine results in increased expression of ACTA2 protein
andrographolide inhibits the reaction [N-acetyl-4-benzoquinoneimine results in increased expression of ACTA2 mRNA]; andrographolide inhibits the reaction [N-acetyl-4-benzoquinoneimine results in increased expression of ACTA2 protein]
CTD PMID:28286204 PMID:29355602 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Adarb2 adenosine deaminase, RNA-specific, B2 affects response to substance ISO ADARB2 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr17:61,750,437...62,300,984
Ensembl chr17:61,756,067...62,300,831
JBrowse link
G Alcam activated leukocyte cell adhesion molecule affects response to substance ISO ALCAM gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 affects response to substance ISO ALDH1A3 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression ISO N-acetyl-4-benzoquinoneimine results in increased expression of BMP2 mRNA CTD PMID:28286204 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 affects response to substance ISO BPNT2 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 5:17,775,684...17,802,570
Ensembl chr 5:17,772,608...17,802,570
JBrowse link
G C11h3orf38 similar to human chromosome 3 open reading frame 38 affects response to substance ISO C3ORF38 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr11:2,483,983...2,488,631
Ensembl chr11:2,481,189...2,488,660
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H affects response to substance ISO CACNA1H gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
JBrowse link
G Cald1 caldesmon 1 affects response to substance ISO CALD1 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 4:63,265,781...63,446,936
Ensembl chr 4:63,265,942...63,446,932
JBrowse link
G Ccdc25 coiled-coil domain containing 25 affects response to substance ISO CCDC25 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr15:40,055,368...40,087,758
Ensembl chr15:40,055,368...40,087,758
JBrowse link
G Cd9 CD9 molecule affects response to substance ISO CD9 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
JBrowse link
G Cep44 centrosomal protein 44 affects response to substance ISO CEP44 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr16:33,711,548...33,733,226
Ensembl chr16:33,711,559...33,733,225
JBrowse link
G Cnr1 cannabinoid receptor 1 affects response to substance ISO CNR1 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression
multiple interactions
ISO N-acetyl-4-benzoquinoneimine results in increased expression of COL1A1 mRNA
andrographolide inhibits the reaction [N-acetyl-4-benzoquinoneimine results in increased expression of COL1A1 mRNA]
CTD PMID:28286204 PMID:29355602 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression ISO N-acetyl-4-benzoquinoneimine results in increased expression of COL1A2 mRNA CTD PMID:28286204 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression
multiple interactions
ISO N-acetyl-4-benzoquinoneimine results in increased expression of COL3A1 mRNA
andrographolide inhibits the reaction [N-acetyl-4-benzoquinoneimine results in increased expression of COL3A1 mRNA]
CTD PMID:28286204 PMID:29355602 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Cpa6 carboxypeptidase A6 affects response to substance ISO CPA6 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 5:8,559,745...8,888,492
Ensembl chr 5:8,526,741...8,888,485
JBrowse link
G Cst5 cystatin D affects response to substance ISO CST5 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 3:137,573,194...137,577,754
Ensembl chr 3:137,573,194...137,577,754
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases abundance
ISO CYP1A2 protein results in increased chemical synthesis of and results in increased abundance of N-acetyl-4-benzoquinoneimine
CYP1A2 protein results in increased abundance of N-acetyl-4-benzoquinoneimine
CTD PMID:19679878 PMID:24661219 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases abundance ISO CYP2D6 protein results in increased abundance of N-acetyl-4-benzoquinoneimine CTD PMID:24661219 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases abundance
increases chemical synthesis
ISO
EXP
CYP2E1 protein results in increased chemical synthesis of and results in increased abundance of N-acetyl-4-benzoquinoneimine
CYP2E1 protein results in increased abundance of N-acetyl-4-benzoquinoneimine
CYP2E1 results in increased chemical synthesis of N-acetyl-4-benzoquinoneimine
CTD PMID:19679878 PMID:20566340 PMID:24661219 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases abundance ISO CYP3A4 protein results in increased abundance of N-acetyl-4-benzoquinoneimine CTD PMID:24661219 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dmrt1 doublesex and mab-3 related transcription factor 1 affects response to substance ISO DMRT1 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 1:223,142,859...223,241,333
Ensembl chr 1:223,142,859...223,241,333
JBrowse link
G Dnttip1 deoxynucleotidyltransferase, terminal, interacting protein 1 affects response to substance ISO DNTTIP1 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 3:153,481,718...153,505,403
Ensembl chr 3:153,481,705...153,505,759
JBrowse link
G Dsc3 desmocollin 3 affects response to substance ISO DSC3 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr18:11,379,759...11,413,797
Ensembl chr18:11,377,347...11,413,797
JBrowse link
G Etnk2 ethanolamine kinase 2 affects response to substance ISO ETNK2 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr13:44,811,224...44,829,037
Ensembl chr13:44,811,015...44,829,037
JBrowse link
G Fbxo39 F-box protein 39 affects response to substance ISO FBXO39 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr10:56,929,699...56,934,911
Ensembl chr10:56,932,297...56,934,906
JBrowse link
G Frk fyn-related Src family tyrosine kinase affects response to substance ISO FRK gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr20:38,265,416...38,371,038
Ensembl chr20:38,265,280...38,371,114
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
affects response to substance
ISO [GPX1 protein co-treated with SOD1 protein] affects the susceptibility to N-acetyl-4-benzoquinoneimine
GPX1 protein affects the susceptibility to N-acetyl-4-benzoquinoneimine
CTD PMID:16636302 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects metabolic processing
multiple interactions
increases glutathionylation
increases metabolic processing
ISO
EXP
GSTP1 protein polymorphism affects the metabolism of N-acetyl-4-benzoquinoneimine metabolite
NQO1 protein inhibits the reaction [GSTP1 protein results in increased glutathionylation of N-acetyl-4-benzoquinoneimine]
GSTP1 protein results in increased metabolism of N-acetyl-4-benzoquinoneimine
CTD PMID:24185126 PMID:24552538 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Hdac4 histone deacetylase 4 affects response to substance ISO HDAC4 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164
JBrowse link
G Hid1 HID1 domain containing affects response to substance ISO HID1 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr10:100,589,555...100,610,050
Ensembl chr10:100,589,555...100,610,041
JBrowse link
G Il23r interleukin 23 receptor affects response to substance ISO IL23R gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 4:96,580,568...96,672,540
Ensembl chr 4:96,580,714...96,674,021
JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 affects response to substance ISO KCNJ3 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 3:39,944,896...40,106,646
Ensembl chr 3:39,945,351...40,109,124
JBrowse link
G Kcnu1 potassium calcium-activated channel subfamily U member 1 affects response to substance ISO KCNU1 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr16:66,141,696...66,229,493
Ensembl chr16:66,141,976...66,229,465
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions
affects metabolic processing
ISO KEAP1 protein inhibits the reaction [NQO1 protein results in increased metabolism of N-acetyl-4-benzoquinoneimine]
N-acetyl-4-benzoquinoneimine affects the metabolism of KEAP1 protein
CTD PMID:18785192 PMID:19246624 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Lama4 laminin subunit alpha 4 affects response to substance ISO LAMA4 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347
JBrowse link
G Lmx1a LIM homeobox transcription factor 1 alpha affects response to substance ISO LMX1A gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr13:79,834,614...79,978,253
Ensembl chr13:79,835,019...79,978,253
JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 affects response to substance ISO MAGI2 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 4:14,388,322...15,870,036
Ensembl chr 4:14,386,399...15,870,240
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO N-acetyl-4-benzoquinoneimine results in increased phosphorylation of MAPK1 protein CTD PMID:28286204 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO N-acetyl-4-benzoquinoneimine results in increased phosphorylation of MAPK3 protein CTD PMID:28286204 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mctp1 multiple C2 and transmembrane domain containing 1 affects response to substance ISO MCTP1 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 2:6,071,408...6,761,833
Ensembl chr 2:6,065,808...6,761,833
JBrowse link
G Mfsd4a major facilitator superfamily domain containing 4A affects response to substance ISO MFSD4A gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr13:43,469,488...43,510,467
Ensembl chr13:43,469,488...43,510,467
JBrowse link
G Mir135a microRNA 135a affects response to substance ISO MIR135A2 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 7:26,611,990...26,612,089
Ensembl chr 7:26,611,990...26,612,089
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression ISO N-acetyl-4-benzoquinoneimine results in increased expression of MMP2 mRNA CTD PMID:28286204 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mtus2 microtubule associated scaffold protein 2 affects response to substance ISO MTUS2 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr12:6,706,531...7,078,331
Ensembl chr12:6,706,532...7,078,331
JBrowse link
G Neb nebulin affects response to substance ISO NEB gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 3:36,613,677...36,811,618
Ensembl chr 3:36,613,716...36,811,574
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects localization
multiple interactions
increases activity
ISO N-acetyl-4-benzoquinoneimine affects the localization of NFE2L2 protein
NFE2L2 protein affects the reaction [N-acetyl-4-benzoquinoneimine results in increased expression of NQO1 mRNA]; NFE2L2 protein promotes the reaction [NQO1 protein results in increased metabolism of N-acetyl-4-benzoquinoneimine]
N-acetyl-4-benzoquinoneimine results in increased activity of NFE2L2 protein
CTD PMID:18785192 PMID:19246624 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nhlrc3 NHL repeat containing 3 affects response to substance ISO NHLRC3 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 2:137,527,843...137,542,258
Ensembl chr 2:137,530,012...137,534,879
Ensembl chr 2:137,530,012...137,534,879
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases reduction
increases metabolic processing
increases expression
ISO KEAP1 protein inhibits the reaction [NQO1 protein results in increased metabolism of N-acetyl-4-benzoquinoneimine]; NFE2L2 protein affects the reaction [N-acetyl-4-benzoquinoneimine results in increased expression of NQO1 mRNA]; NFE2L2 protein promotes the reaction [NQO1 protein results in increased metabolism of N-acetyl-4-benzoquinoneimine]
NQO1 protein inhibits the reaction [GSTP1 protein results in increased glutathionylation of N-acetyl-4-benzoquinoneimine]
NQO1 protein results in increased reduction of N-acetyl-4-benzoquinoneimine
CTD PMID:17188792 PMID:18785192 PMID:19246624 PMID:24552538 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 multiple interactions ISO NQO2 protein results in increased reduction of and results in decreased glutathionylation of N-acetyl-4-benzoquinoneimine; Tacrine inhibits the reaction [NQO2 protein results in increased reduction of N-acetyl-4-benzoquinoneimine] CTD PMID:29281794 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320
JBrowse link
G Pcbd2 pterin-4 alpha-carbinolamine dehydratase 2 affects response to substance ISO PCBD2 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr17:8,845,161...8,896,343
Ensembl chr17:8,845,084...8,910,539
JBrowse link
G Pvt1 Pvt1 oncogene affects response to substance ISO PVT1 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 7:93,656,249...93,879,938 JBrowse link
G Rab3il1 RAB3A interacting protein-like 1 affects response to substance ISO RAB3IL1 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 1:206,646,168...206,682,718
Ensembl chr 1:206,646,155...206,679,972
JBrowse link
G Rap1gap2 RAP1 GTPase activating protein 2 affects response to substance ISO RAP1GAP2 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr10:59,255,278...59,472,536
Ensembl chr10:59,255,278...59,472,170
JBrowse link
G Slc39a11 solute carrier family 39, member 11 affects response to substance ISO SLC39A11 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr10:98,275,958...98,697,042
Ensembl chr10:98,275,960...98,611,295
JBrowse link
G Slit2 slit guidance ligand 2 affects response to substance ISO SLIT2 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948
JBrowse link
G Snx16 sorting nexin 16 affects response to substance ISO SNX16 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 2:91,335,896...91,357,622
Ensembl chr 2:91,336,092...91,357,619
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [GPX1 protein co-treated with SOD1 protein] affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:16636302 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Spag16 sperm associated antigen 16 affects response to substance ISO SPAG16 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 9:71,333,005...72,252,772
Ensembl chr 9:71,332,992...72,252,708
JBrowse link
G Stab1 stabilin 1 affects response to substance ISO STAB1 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr16:6,330,435...6,360,934
Ensembl chr16:6,330,444...6,360,923
JBrowse link
G Syne3 spectrin repeat containing, nuclear envelope family member 3 affects response to substance ISO SYNE3 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 6:123,872,895...123,964,773
Ensembl chr 6:123,873,174...123,953,409
JBrowse link
G Tac1 tachykinin, precursor 1 increases secretion EXP N-acetyl-4-benzoquinoneimine results in increased secretion of TAC1 protein CTD PMID:20720158 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO N-acetyl-4-benzoquinoneimine results in increased expression of TGFB1 mRNA CTD PMID:28286204 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO N-acetyl-4-benzoquinoneimine results in increased expression of TIMP1 mRNA CTD PMID:28286204 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Top2a DNA topoisomerase II alpha decreases activity ISO N-acetyl-4-benzoquinoneimine results in decreased activity of TOP2A protein CTD PMID:15035644 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tpd52l1 TPD52 like 1 affects response to substance ISO TPD52L1 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity
affects response to substance
multiple interactions
ISO
EXP
N-acetyl-4-benzoquinoneimine results in increased activity of TRPA1 protein
TRPA1 affects the susceptibility to N-acetyl-4-benzoquinoneimine
2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [N-acetyl-4-benzoquinoneimine results in increased activity of TRPA1 protein]
CTD PMID:20720158 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases activity
multiple interactions
EXP N-acetyl-4-benzoquinoneimine results in decreased activity of TXNRD1 protein
Glutathione inhibits the reaction [N-acetyl-4-benzoquinoneimine results in decreased activity of TXNRD1 protein]
CTD PMID:24661219 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Ubash3a ubiquitin associated and SH3 domain containing, A affects response to substance ISO UBASH3A gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr20:9,291,471...9,334,685
Ensembl chr20:9,292,139...9,329,224
JBrowse link
G Ube2e2 ubiquitin-conjugating enzyme E2E 2 affects response to substance ISO UBE2E2 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr15:6,980,195...7,257,912
Ensembl chr15:6,980,474...7,257,532
JBrowse link
G Vwc2 von Willebrand factor C domain containing 2 affects response to substance ISO VWC2 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr14:85,683,670...85,825,068
Ensembl chr14:85,684,414...85,818,524
JBrowse link
G Wfdc3 WAP four-disulfide core domain 3 affects response to substance ISO WFDC3 gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine CTD PMID:21177773 NCBI chr 3:153,464,862...153,478,952
Ensembl chr 3:153,464,862...153,478,952
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20072
    chemical entity 20071
      atom 20071
        nonmetal atom 19963
          carbon atom 19896
            organic molecular entity 19896
              imine 189
                quinone imine 132
                  1,4-benzoquinone imine + 73
                  2,6-dichloroindophenol 24
                  4'-hydroxydiclofenac quinone imine 0
                  5-hydroxydiclofenac quinone imine 0
                  6-iminocyclohexa-2,4-dienone 0
                  Bandrowski's base 42
                  LSM-32594 0
                  N-3,5-dichloro-4-hydroxyphenyl-1,4-benzoquinone imine 0
                  N-acetyl-1,4-benzoquinone imine 73
                  NG-061 0
                  indophenol + 24
                  para-Benzoquinone dioxime 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20072
    subatomic particle 20071
      composite particle 20071
        hadron 20071
          baryon 20071
            nucleon 20071
              atomic nucleus 20071
                atom 20071
                  main group element atom 19974
                    p-block element atom 19974
                      p-block molecular entity 19974
                        carbon group molecular entity 19903
                          organic molecular entity 19896
                            heteroorganic entity 19607
                              organonitrogen compound 18842
                                imine 189
                                  quinone imine 132
                                    1,4-benzoquinone imine + 73
                                    2,6-dichloroindophenol 24
                                    4'-hydroxydiclofenac quinone imine 0
                                    5-hydroxydiclofenac quinone imine 0
                                    6-iminocyclohexa-2,4-dienone 0
                                    Bandrowski's base 42
                                    LSM-32594 0
                                    N-3,5-dichloro-4-hydroxyphenyl-1,4-benzoquinone imine 0
                                    N-acetyl-1,4-benzoquinone imine 73
                                    NG-061 0
                                    indophenol + 24
                                    para-Benzoquinone dioxime 0
paths to the root