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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pamoic acid
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Accession:CHEBI:50186 term browser browse the term
Definition:A dicarboxylic acid that has formula C23H16O6.
Synonyms:exact_synonym: 4,4'-methylenebis(3-hydroxynaphthalene-2-carboxylic acid)
 related_synonym: 4,4'-Methylen-bis-(3-hydroxy-2-naphthoesaeure);   4,4'-Methylenebis(3-hydroxy-2-naphthoic acid);   Embonic acid;   Formula=C23H16O6;   InChI=1S/C23H16O6/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29/h1-10,24-25H,11H2,(H,26,27)(H,28,29);   InChIKey=WLJNZVDCPSBLRP-UHFFFAOYSA-N;   Pamosaeure;   SMILES=OC(=O)c1cc2ccccc2c(Cc2c(O)c(cc3ccccc23)C(O)=O)c1O
 xref: Beilstein:901319;   CAS:130-85-8
 xref_mesh: MESH:C004368
 cyclic_relationship: is_conjugate_acid_of CHEBI:50187


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pamoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 multiple interactions ISO pamoic acid promotes the reaction [ARRB2 protein binds to GPR35 protein] CTD PMID:20826425 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Gpr35 G protein-coupled receptor 35 multiple interactions ISO pamoic acid binds to and results in increased activity of GPR35 protein; pamoic acid promotes the reaction [ARRB2 protein binds to GPR35 protein] CTD PMID:20826425 NCBI chr 9:100,129,428...100,141,269
Ensembl chr 9:100,137,881...100,138,801
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO pamoic acid results in increased phosphorylation of and results in increased activity of MAPK1 protein; Pertussis Toxin inhibits the reaction [pamoic acid results in increased phosphorylation of and results in increased activity of MAPK1 protein]; U 0126 inhibits the reaction [pamoic acid results in increased phosphorylation of and results in increased activity of MAPK1 protein] CTD PMID:20826425 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO pamoic acid results in increased phosphorylation of and results in increased activity of MAPK3 protein; Pertussis Toxin inhibits the reaction [pamoic acid results in increased phosphorylation of and results in increased activity of MAPK3 protein]; U 0126 inhibits the reaction [pamoic acid results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:20826425 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19761
    role 19711
      biological role 19711
        biochemical role 19301
          metabolite 19282
            xenobiotic metabolite 14244
              2-naphthoic acid 14
                pamoic acid 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19761
    subatomic particle 19759
      composite particle 19759
        hadron 19759
          baryon 19759
            nucleon 19759
              atomic nucleus 19759
                atom 19759
                  main group element atom 19653
                    p-block element atom 19653
                      carbon group element atom 19569
                        carbon atom 19559
                          organic molecular entity 19559
                            organic group 18593
                              organic divalent group 18584
                                organodiyl group 18584
                                  carbonyl group 18499
                                    carbonyl compound 18499
                                      carboxylic acid 18151
                                        aromatic carboxylic acid 11266
                                          naphthoic acid 43
                                            2-naphthoic acid 14
                                              pamoic acid 4
paths to the root