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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pamoic acid
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Accession:CHEBI:50186 term browser browse the term
Definition:A dicarboxylic acid that has formula C23H16O6.
Synonyms:exact_synonym: 4,4'-methylenebis(3-hydroxynaphthalene-2-carboxylic acid)
 related_synonym: 4,4'-Methylen-bis-(3-hydroxy-2-naphthoesaeure);   4,4'-Methylenebis(3-hydroxy-2-naphthoic acid);   Embonic acid;   Formula=C23H16O6;   InChI=1S/C23H16O6/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29/h1-10,24-25H,11H2,(H,26,27)(H,28,29);   InChIKey=WLJNZVDCPSBLRP-UHFFFAOYSA-N;   Pamosaeure;   SMILES=OC(=O)c1cc2ccccc2c(Cc2c(O)c(cc3ccccc23)C(O)=O)c1O
 xref: Beilstein:901319;   CAS:130-85-8
 xref_mesh: MESH:C004368
 cyclic_relationship: is_conjugate_acid_of CHEBI:50187



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pamoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 multiple interactions ISO pamoic acid promotes the reaction [ARRB2 protein binds to GPR35 protein] CTD PMID:20826425 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Gpr35 G protein-coupled receptor 35 multiple interactions ISO pamoic acid binds to and results in increased activity of GPR35 protein; pamoic acid promotes the reaction [ARRB2 protein binds to GPR35 protein] CTD PMID:20826425 NCBI chr 9:93,526,691...93,539,302
Ensembl chr 9:93,527,127...93,539,299
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO pamoic acid results in increased phosphorylation of and results in increased activity of MAPK1 protein; Pertussis Toxin inhibits the reaction [pamoic acid results in increased phosphorylation of and results in increased activity of MAPK1 protein]; U 0126 inhibits the reaction [pamoic acid results in increased phosphorylation of and results in increased activity of MAPK1 protein] CTD PMID:20826425 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO pamoic acid results in increased phosphorylation of and results in increased activity of MAPK3 protein; Pertussis Toxin inhibits the reaction [pamoic acid results in increased phosphorylation of and results in increased activity of MAPK3 protein]; U 0126 inhibits the reaction [pamoic acid results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:20826425 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        biochemical role 19368
          metabolite 19344
            xenobiotic metabolite 14500
              2-naphthoic acid 14
                pamoic acid 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic group 18718
                              organic divalent group 18702
                                organodiyl group 18702
                                  carbonyl group 18651
                                    carbonyl compound 18651
                                      carboxylic acid 18346
                                        aromatic carboxylic acid 11735
                                          naphthoic acid 43
                                            2-naphthoic acid 14
                                              pamoic acid 4
paths to the root