Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chavicol
go back to main search page
Accession:CHEBI:50158 term browser browse the term
Definition:A phenylpropanoid that is phenol substituted by a prop-2-enyl group at position 4.
Synonyms:related_synonym: 4-(2-Propenyl)phenol;   4-(Prop-2-enyl)-phenol;   4-Allylphenol;   Formula=C9H10O;   InChI=1S/C9H10O/c1-2-3-8-4-6-9(10)7-5-8/h2,4-7,10H,1,3H2;   InChIKey=RGIBXDHONMXTLI-UHFFFAOYSA-N;   SMILES=Oc1ccc(CC=C)cc1;   gamma-(p-hydroxyphenyl)-alpha-propylene;   p-Allylphenol;   p-Chavicol;   p-Hydroxyallylbenzene
 xref: Beilstein:2039682;   CAS:501-92-8;   KEGG:C16930


show annotations for term's descendants           Sort by:
 
1'-acetoxychavicol acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of BCL2 protein] CTD PMID:15905586 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2a1 BCL2-related protein A1 multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of BCL2A1 protein] CTD PMID:15905586 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of BCL2L1 protein] CTD PMID:15905586 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of BIRC2 protein] CTD PMID:15905586 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of BIRC3 protein] CTD PMID:15905586 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of BIRC5 protein] CTD PMID:15905586 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of CCND1 protein] CTD PMID:15905586 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of CFLAR protein] CTD PMID:15905586 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased activity of CHUK protein] CTD PMID:15905586 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions
ISO 1'-acetoxychavicol acetate analog results in decreased activity of GSR protein
1'-acetoxychavicol acetate analog inhibits the reaction [GSR protein results in increased reduction of Glutathione]
CTD PMID:20230805 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:15905586 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased activity of IKBKB protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of IKBKB protein] CTD PMID:15905586 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [IL1B protein results in increased activity of NFKB1 protein]; 1'-acetoxychavicol acetate inhibits the reaction [IL1B protein results in increased activity of RELA protein] CTD PMID:15905586 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of MAP3K14 protein] CTD PMID:15905586 NCBI chr10:91,303,428...91,353,601
Ensembl chr10:91,303,428...91,353,601
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO 1'-acetoxychavicol acetate results in increased phosphorylation of MAPK1 protein
[1'-acetoxychavicol acetate co-treated with Butyric Acid] results in increased phosphorylation of MAPK1 protein
CTD PMID:24480522 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO [1'-acetoxychavicol acetate co-treated with Butyric Acid] results in increased phosphorylation of MAPK3 protein
1'-acetoxychavicol acetate results in increased phosphorylation of MAPK3 protein
CTD PMID:24480522 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of MMP9 protein] CTD PMID:15905586 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of MYC protein] CTD PMID:15905586 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [Doxorubicin results in increased activity of NFKB1 protein]; 1'-acetoxychavicol acetate inhibits the reaction [Hydrogen Peroxide results in increased activity of NFKB1 protein]; 1'-acetoxychavicol acetate inhibits the reaction [IL1B protein results in increased activity of NFKB1 protein]; 1'-acetoxychavicol acetate inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein]; 1'-acetoxychavicol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NFKB1 protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased activity of NFKB1 protein] CTD PMID:15905586 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein] CTD PMID:15905586 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO 1'-acetoxychavicol acetate promotes the reaction [TNF protein results in increased cleavage of PARP1 protein] CTD PMID:15905586 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of PTGS2 protein] CTD PMID:15905586 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases activity
ISO 1'-acetoxychavicol acetate inhibits the reaction [Doxorubicin results in increased activity of RELA protein]; 1'-acetoxychavicol acetate inhibits the reaction [Hydrogen Peroxide results in increased activity of RELA protein]; 1'-acetoxychavicol acetate inhibits the reaction [IL1B protein results in increased activity of RELA protein]; 1'-acetoxychavicol acetate inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]; 1'-acetoxychavicol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein affects the localization of RELA protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased activity of RELA protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]
1'-acetoxychavicol acetate results in decreased activity of RELA protein
CTD PMID:15905586 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein affects the localization of RELA protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased activity of CHUK protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased activity of IKBKB protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased activity of RELA protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of BCL2 protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of BCL2A1 protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of BCL2L1 protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of BIRC3 protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of BIRC5 protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of CCND1 protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of CFLAR protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of IKBKB protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of MAP3K14 protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of MMP9 protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of MYC protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of TNFRSF1A protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of TRADD protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of TRAF1 protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of TRAF2 protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of VEGFA protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of XIAP protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]; 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]; 1'-acetoxychavicol acetate promotes the reaction [TNF protein results in increased cleavage of PARP1 protein] CTD PMID:15905586 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of TNFRSF1A protein] CTD PMID:15905586 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [1'-acetoxychavicol acetate co-treated with Butyric Acid] results in increased phosphorylation of TP53 protein CTD PMID:24480522 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tradd TNFRSF1A-associated via death domain multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of TRADD protein] CTD PMID:15905586 NCBI chr19:37,214,461...37,221,099
Ensembl chr19:37,214,471...37,216,572
JBrowse link
G Traf1 TNF receptor-associated factor 1 multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of TRAF1 protein] CTD PMID:15905586 NCBI chr 3:14,003,340...14,022,955
Ensembl chr 3:14,003,340...14,022,672
JBrowse link
G Traf2 Tnf receptor-associated factor 2 multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of TRAF2 protein] CTD PMID:15905586 NCBI chr 3:2,746,061...2,770,690
Ensembl chr 3:2,746,075...2,770,620
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of VEGFA protein] CTD PMID:15905586 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions ISO 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of XIAP protein] CTD PMID:15905586 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    chemical entity 19816
      molecular entity 19814
        polyatomic entity 19727
          heteroatomic molecular entity 19653
            hydroxides 19107
              organic hydroxy compound 18661
                phenols 18145
                  chavicol 31
                    1'-acetoxychavicol acetate 31
                    chavicol hydrogen sulfate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic molecule 19522
                              organic cyclic compound 19320
                                organic aromatic compound 19154
                                  phenylpropanoid 9281
                                    chavicol 31
                                      1'-acetoxychavicol acetate 31
                                      chavicol hydrogen sulfate 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.