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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:triazane
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Accession:CHEBI:50155 term browser browse the term
Definition:A nitrogen hydride that has formula H5N3.
Synonyms:related_synonym: Formula=H5N3;   InChI=1S/H5N3/c1-3-2/h3H,1-2H2;   InChIKey=PYHOFAHZHOBVGV-UHFFFAOYSA-N;   SMILES=NNN
 xref: Gmelin:24980


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1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 increases expression EXP 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of BMP4 mRNA CTD PMID:15991191 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Cav1 caveolin 1 multiple interactions
increases expression
ISO 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in decreased ubiquitination of and results in decreased degradation of CAV1 protein; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased metabolism of and results in increased stability of CAV1 protein
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CAV1 protein
CTD PMID:19706615 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Ccn4 cellular communication network factor 4 multiple interactions
increases expression
ISO CREB1 mutant form inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 mRNA]; CTNNB1 mutant form inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 mRNA]; Cycloheximide inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 mRNA]; Dactinomycin inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 mRNA]
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 mRNA; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 protein
CTD PMID:19238344 NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248
JBrowse link
G Cdh2 cadherin 2 increases expression
affects response to substance
multiple interactions
ISO
EXP
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CDH2 mRNA
CDH2 protein affects the susceptibility to 2,2'-(hydroxynitrosohydrazono)bis-ethanamine
CDH2 protein affects the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CTNNB1 mRNA]
CTD PMID:16580782 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation
multiple interactions
ISO 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased phosphorylation of CREB1 protein
CREB1 mutant form inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 mRNA]
CTD PMID:19238344 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Ctnnb1 catenin beta 1 increases expression
increases activity
multiple interactions
ISO 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CTNNB1 mRNA
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased activity of CTNNB1 protein
CDH2 protein affects the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CTNNB1 mRNA]; CTNNB1 mutant form inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 mRNA]
CTD PMID:16580782 PMID:19238344 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity EXP 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in decreased activity of CYP1A1 protein CTD PMID:15542068 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity EXP 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in decreased activity of CYP1A2 protein CTD PMID:15542068 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression ISO 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in decreased expression of GFAP mRNA CTD PMID:16580782 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D multiple interactions
increases expression
EXP 2,2'-(hydroxynitrosohydrazono)bis-ethanamine promotes the reaction [HNRNPD protein binds to MMP9 3' UTR]; HNRNPD mutant form inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of MMP9 protein]]
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of HNRNPD protein
CTD PMID:16683234 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO 2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [Fructose results in increased expression of ICAM1 protein] CTD PMID:18508964 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP 2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [IL1B protein results in increased activity of MMP9 protein]; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [IL1B protein results in increased expression of MMP9 mRNA] CTD PMID:16378139 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP 2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [IL1B protein results in increased activity of MMP9 protein]; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [IL1B protein results in increased expression of MMP9 mRNA]; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of MMP9 protein]; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA]; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine promotes the reaction [HNRNPD protein binds to MMP9 3' UTR]; HNRNPD mutant form inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of MMP9 protein]] CTD PMID:16378139 PMID:16683234 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 increases metabolic processing ISO 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased metabolism of NCF1 protein CTD PMID:17568572 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
G Neurog1 neurogenin 1 increases expression ISO 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of NEUROG1 mRNA CTD PMID:16580782 NCBI chr17:8,362,878...8,364,397
Ensembl chr17:8,362,821...8,364,571
JBrowse link
G Rasd1 ras related dexamethasone induced 1 multiple interactions EXP 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased nitrosation of and results in increased activity of RASD1 protein CTD PMID:16908409 NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186
JBrowse link
G Slc26a4 solute carrier family 26 member 4 decreases expression ISO 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in decreased expression of SLC26A4 protein CTD PMID:22811483 NCBI chr 6:48,107,575...48,153,762
Ensembl chr 6:48,107,588...48,145,703
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases response to substance
EXP
ISO
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [[2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased abundance of Nitric Oxide] which results in increased expression of and results in increased activity of SOD2 protein]; 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [[2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased abundance of Nitric Oxide] which results in increased expression of SOD2 mRNA]; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [Doxorubicin results in increased expression of SOD2 protein]; [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased abundance of Nitric Oxide] which results in increased expression of and results in increased activity of SOD2 protein; [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased abundance of Nitric Oxide] which results in increased expression of SOD2 mRNA; Dactinomycin inhibits the reaction [[2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased abundance of Nitric Oxide] which results in increased expression of SOD2 mRNA]
SOD2 protein results in increased susceptibility to 2,2'-(hydroxynitrosohydrazono)bis-ethanamine
CTD PMID:10511315 PMID:14996425 PMID:19286953 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of TGFB1 mRNA; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of TGFB1 protein CTD PMID:12798441 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 multiple interactions EXP 2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [lead acetate affects the localization of VAMP2 protein] CTD PMID:22265330 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    chemical entity 19821
      atom 19819
        nonmetal atom 19707
          nitrogen atom 18765
            nitrogen molecular entity 18765
              nitrogen hydride 17545
                triazane 20
                  1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane 20
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    main group molecular entity 19716
                      s-block molecular entity 19502
                        hydrogen molecular entity 19498
                          hydrides 18852
                            inorganic hydride 17691
                              pnictogen hydride 17672
                                nitrogen hydride 17545
                                  triazane 20
                                    1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane 20
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