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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2-hydroxyisobutyric acid
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Accession:CHEBI:50129 term browser browse the term
Definition:A 2-hydroxy monocarboxylic acid that is isobutyric acid bearing a hydroxy substituent at position 2. It is a metabolite of methyl tertiary-butyl ether.
Synonyms:exact_synonym: 2-hydroxy-2-methylpropanoic acid
 related_synonym: 2-Hydroxy-2-methylpropionic acid;   2-Hydroxy-2-methylpropionsaeure;   2-Methyl-2-hydroxypropionsaeure;   2-Methyllactic acid;   2-methyl-2-hydroxypropanoic acid;   Acetonic acid;   Formula=C4H8O3;   HIBA;   Hydroxydimethylacetic acid;   InChI=1S/C4H8O3/c1-4(2,7)3(5)6/h7H,1-2H3,(H,5,6);   InChIKey=BWLBGMIXKSTLSX-UHFFFAOYSA-N;   SMILES=CC(C)(O)C(O)=O;   acide 2-hydroxy-2-methylpropanoique;   acido 2-hidroxi-2-metilpropionico;   alpha-hydroxy-alpha-methylpropanoic acid;   alpha-hydroxy-alpha-methylpropionic acid;   alpha-hydroxyisobutanoic acid;   alpha-hydroxyisobutyric acid
 xref: Beilstein:1744739;   CAS:594-61-6;   HMDB:HMDB0000729
 xref_mesh: MESH:C008039
 xref: PMID:12563344;   PMID:12775515;   PMID:17190852;   PMID:20184738;   Patent:WO2009135074;   Reaxys:1744739
 cyclic_relationship: is_conjugate_acid_of CHEBI:19641



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2-hydroxyisobutyric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor affects abundance ISO LEPR affects the abundance of 2-hydroxyisobutyric acid CTD PMID:20567778 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19795
    role 19746
      biological role 19746
        biochemical role 19361
          volatile oil component 6579
            isobutyric acid 3100
              2-hydroxyisobutyric acid 1
                1,30-diacetyltrichagmalin F 0
                30-acetyltrichagmalin F 0
                trichagmalin F + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19795
    subatomic particle 19794
      composite particle 19794
        hadron 19794
          baryon 19794
            nucleon 19794
              atomic nucleus 19794
                atom 19794
                  main group element atom 19693
                    p-block element atom 19693
                      carbon group element atom 19614
                        carbon atom 19604
                          organic molecular entity 19604
                            organic group 18713
                              organic divalent group 18697
                                organodiyl group 18697
                                  carbonyl group 18646
                                    carbonyl compound 18646
                                      carboxylic acid 18341
                                        monocarboxylic acid 17618
                                          fatty acid 16009
                                            short-chain fatty acid 15698
                                              fatty acid 4:0 7902
                                                isobutyric acid 3100
                                                  2-hydroxyisobutyric acid 1
                                                    1,30-diacetyltrichagmalin F 0
                                                    30-acetyltrichagmalin F 0
                                                    trichagmalin F + 0
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