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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tetrasaccharide
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Accession:CHEBI:50126 term browser browse the term
Definition:An oligosaccharide comprising four monomeric monosaccharide units.
Synonyms:related_synonym: tetrasaccharides
 alt_id: CHEBI:26934;   CHEBI:9503
 xref: KEGG:C06768


show annotations for term's descendants           Sort by:
acarbose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 decreases expression ISO Acarbose results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO Acarbose results in increased expression of ADIPOQ protein CTD PMID:18290871 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Acarbose inhibits the reaction [Fructose results in increased expression of CCL2 mRNA]; Acarbose inhibits the reaction [Fructose results in increased expression of CCL2 protein] CTD PMID:17133782 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression ISO Acarbose results in decreased expression of CYP2E1 mRNA CTD PMID:14975757 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900 		JBrowse link
G Fasn fatty acid synthase decreases expression ISO Acarbose results in decreased expression of FASN mRNA; Acarbose results in decreased expression of FASN protein CTD PMID:8101498 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373 		JBrowse link
G Ins1 insulin I increases secretion
increases response to substance
decreases secretion
multiple interactions
decreases expression		 ISO Acarbose results in increased secretion of INS1 protein
Acarbose results in increased susceptibility to INS1 protein
Acarbose results in decreased secretion of INS1 protein
Acarbose inhibits the reaction [[Dietary Sucrose co-treated with Sodium Chloride, Dietary] results in increased expression of INS1 protein]
Acarbose results in decreased expression of INS1 protein		 CTD PMID:1767839 PMID:8101498 PMID:9313782 PMID:18290871 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914 		JBrowse link
G Lep leptin decreases expression ISO Acarbose results in decreased expression of LEP protein CTD PMID:18290871 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876 		JBrowse link
G Mgam maltase-glucoamylase decreases activity ISO
EXP		 Acarbose results in decreased activity of MGAM protein CTD PMID:17585022 PMID:20349118 NCBI chr 6:40,605,765...40,746,057
Ensembl chr 6:40,605,765...40,746,057 		JBrowse link
G Npy neuropeptide Y decreases expression ISO Acarbose results in decreased expression of NPY protein CTD PMID:18290871 NCBI chr 6:49,799,690...49,806,487
Ensembl chr 6:49,799,690...49,806,487 		JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha affects response to substance ISO PPARGC1A protein polymorphism affects the susceptibility to Acarbose CTD PMID:15592662 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068 		JBrowse link
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 increases expression ISO Acarbose results in increased expression of SLC2A1 protein CTD PMID:11779583 NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180 		JBrowse link
G Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 increases expression ISO Acarbose results in increased expression of SLC2A4 mRNA; Acarbose results in increased expression of SLC2A4 protein CTD PMID:1767839 NCBI chr11:69,833,112...69,839,040
Ensembl chr11:69,833,365...69,839,014 		JBrowse link
G Sqstm1 sequestosome 1 affects response to substance EXP SQSTM1 affects the susceptibility to Acarbose CTD PMID:19207582 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654 		JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions		 EXP
ISO		 Acarbose results in decreased expression of TNF mRNA
Acarbose results in decreased expression of TNF mRNA; Acarbose results in decreased expression of TNF protein
Acarbose inhibits the reaction [Oxygen deficiency results in increased expression of TNF mRNA]		 CTD PMID:12717270 PMID:14975757 PMID:20703014 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP ganglioside, GD1b analog inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 results in increased activity of NOS2 protein] which results in increased secretion of Nitrites]; ganglioside, GD1b inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 results in increased activity of NOS2 protein] which results in increased secretion of Nitrites] CTD PMID:31202640 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
verbascose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions ISO verbascose inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of CXCL8 protein] CTD PMID:33130239 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Ifng interferon gamma multiple interactions ISO [Gallic Acid co-treated with Butyric Acid co-treated with verbascose] affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of IL1B protein]; verbascose affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of IL1B protein]; verbascose inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of CXCL8 protein]; verbascose promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of TNF protein] CTD PMID:33130239 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Gallic Acid co-treated with Butyric Acid co-treated with verbascose] affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of IL1B protein]; verbascose affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of IL1B protein] CTD PMID:33130239 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO verbascose promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of TNF protein] CTD PMID:33130239 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22222
    chemical entity 22221
      atom 22214
        nonmetal atom 22093
          oxygen atom 21454
            oxygen molecular entity 21454
              organooxygen compound 20889
                carbohydrates and carbohydrate derivatives 16041
                  glycan 8833
                    oligosaccharide 621
                      tetrasaccharide 18
                        1(F)-alpha-D-galactosylraffinose 0
                        1,6-kestotetraose 0
                        2,2'-difucosyllactose 0
                        3'-Sialyl-3-fucosyllactose 0
                        6,6-kestotetraose 0
                        6-C-Me-alpha-D-Manp-(1->2)-alpha-D-Manp-(1->2)-alpha-D-Manp-(1->3)-alpha-D-Manp 0
                        D-cellotetraono-1,5-lactone 0
                        D-maltotetraono-1,5-lactone 0
                        D-xylotetraono-1,5-lactone 0
                        L-alpha-D-Hepp-(1->2)-L-alpha-D-Hepp-(1->3)-[beta-Glcp-(1->4)]-L-alpha-D-Hepp 0
                        L-alpha-D-Hepp-(1->7)-L-alpha-D-Hepp-(1->3)-L-alpha-D-Hepp-(1->5)-alpha-Kdo + 0
                        L-glycero-alpha-D-manno-Hepp-(1->2)-L-glycero-alpha-D-manno-Hepp-(1->3)-L-glycero-alpha-D-manno-Hepp-(1->5)-alpha-Kdo 0
                        Lactodifucotetraose 0
                        N,N',N'',N'''-tetraacetylchitotetraono-1,5-lactone 0
                        alpha-D-Abep-(1->3)-alpha-D-Manp-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-Galp 0
                        alpha-D-Gal-(1->6)-alpha-D-Gal-(1->6)-beta-D-Glc-(1<->2)-Fru 0
                        alpha-D-Galp-(1->2)-[alpha-D-Abep-(1->3)]-alpha-D-Manp-(1->4)-alpha-L-Rhap 0
                        alpha-D-Galp-(1->3)-[alpha-L-Fucp-(1->2)]-beta-D-Galp-(1->3)-beta-D-Galp + 0
                        alpha-D-Galp-(1->3)-[alpha-L-Fucp-(1->2)]-beta-D-Galp-(1->4)-beta-D-Glcp + 0
                        alpha-D-Galp-(1->3)-alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                        alpha-D-Galp-(1->3)-alpha-D-Glcp-(1->3)-alpha-L-Rhap-(1->3)-D-ribitol 0
                        alpha-D-Galp-(1->3)-alpha-D-Glcp-(1->3)-alpha-L-Rhap-(1->4)-D-ribitol 0
                        alpha-D-Galp-(1->4)-beta-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-Glcp 0
                        alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp-(1->4)-beta-D-Glcp 0
                        alpha-D-Galp-(1->6)-beta-D-Manp-(1->4)-beta-D-Manp-(1->4)-D-Manp 0
                        alpha-D-GalpA-(1->4)-alpha-D-GalpA-(1->4)-alpha-D-GalpA-(1->4)-alpha-D-GalpA 0
                        alpha-D-Glcp-(1->3)-alpha-D-Glcp-(1->3)-alpha-L-Rhap-(1->3)-D-ribitol 0
                        alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->8)-alpha-D-Kdo-(2->4)-alpha-D-Kdo 0
                        alpha-D-Kdo-(2->8)-[alpha-D-Kdo-(2->4)]-alpha-D-Kdo-(2->4)-alpha-D-Kdo 0
                        alpha-D-Manp-(1->3)-[alpha-D-Manp-(1->6)]-[beta-D-Xylp-(1->2)]-beta-D-Manp 0
                        alpha-D-Xyl-(1->3)-beta-D-GlcA-(1->3)-alpha-D-Xyl-(1->3)-beta-D-GlcA 0
                        alpha-D-Xyl-(1->6)-[alpha-D-Xyl-(1->6)-beta-D-Glc-(->4)]-beta-D-Glc 0
                        alpha-D-galactosyl-(1->6)-alpha-D-galactosyl-(1->6)-beta-D-fructosyl alpha-D-glucoside 0
                        alpha-L-Fucp-(1->2)-[alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)]-beta-D-Galp 0
                        alpha-L-Fucp-(1->2)-beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-D-Glcp + 0
                        alpha-L-Fucp-(1->3)-[alpha-L-Fucp-(1->2)-beta-D-Galp-(1->4)]-beta-D-Glcp + 0
                        alpha-L-Rhap-(1->2)-alpha-L-Rhap-(1->3)-alpha-L-Rhap-(1->2)-alpha-L-Rhap 0
                        alpha-Parp-(1->3)-alpha-D-Manp-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-Galp 0
                        alpha-Tyvp-(1->3)-alpha-D-Manp-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-Galp 0
                        arabinotetraose + 0
                        beta-(1->6)-galactotetraitol 0
                        beta-D-Delta(4)-GlcpA-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-D-Glcp + 0
                        beta-D-Galf-(1->5)-beta-D-Galf-(1->6)-alpha-D-Manp-(1->6)-D-Manp 0
                        beta-D-Galp-(1->4)-[alpha-D-Manp-(1->2)-alpha-D-Manp-(1->2)]-alpha-D-Manp + 0
                        beta-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                        beta-D-Galp-(1->6)-beta-D-Galp-(1->4)-beta-D-Galp-(1->3)-L-Man-OH 0
                        beta-D-Glcp-(1->4)-[alpha-D-GlcpA-(1->3)]-beta-D-Manp-(1->4)-alpha-D-Glcp + 0
                        beta-D-GlcpA-(1->3)-beta-D-Galp-(1->3)-beta-D-Galp-(1->4)-beta-D-Xylp 0
                        beta-D-Manp-(1->3)-beta-D-Manp-(1->3)-alpha-L-Rhap-(1->3)-beta-D-Glcp + 0
                        cyclobis-(1->6)-alpha-nigerosyl 0
                        galacotetraose + 0
                        glucotetraose + 0
                        mannotetraose + 0
                        stachyose + 4
                        tetragalacturonic acid hydroxymethylester 0
                        tetrasaccharide derivative + 15
                        xylotetraose 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22222
    subatomic particle 22214
      composite particle 22214
        hadron 22214
          baryon 22214
            nucleon 22214
              atomic nucleus 22214
                atom 22214
                  main group element atom 22145
                    p-block element atom 22145
                      carbon group element atom 21940
                        carbon atom 21880
                          organic molecular entity 21880
                            heteroorganic entity 21548
                              organochalcogen compound 21043
                                organooxygen compound 20889
                                  carbohydrates and carbohydrate derivatives 16041
                                    carbohydrate 16041
                                      oligosaccharide 621
                                        tetrasaccharide 18
                                          1(F)-alpha-D-galactosylraffinose 0
                                          1,6-kestotetraose 0
                                          2,2'-difucosyllactose 0
                                          3'-Sialyl-3-fucosyllactose 0
                                          6,6-kestotetraose 0
                                          6-C-Me-alpha-D-Manp-(1->2)-alpha-D-Manp-(1->2)-alpha-D-Manp-(1->3)-alpha-D-Manp 0
                                          D-cellotetraono-1,5-lactone 0
                                          D-maltotetraono-1,5-lactone 0
                                          D-xylotetraono-1,5-lactone 0
                                          L-alpha-D-Hepp-(1->2)-L-alpha-D-Hepp-(1->3)-[beta-Glcp-(1->4)]-L-alpha-D-Hepp 0
                                          L-alpha-D-Hepp-(1->7)-L-alpha-D-Hepp-(1->3)-L-alpha-D-Hepp-(1->5)-alpha-Kdo + 0
                                          L-glycero-alpha-D-manno-Hepp-(1->2)-L-glycero-alpha-D-manno-Hepp-(1->3)-L-glycero-alpha-D-manno-Hepp-(1->5)-alpha-Kdo 0
                                          Lactodifucotetraose 0
                                          N,N',N'',N'''-tetraacetylchitotetraono-1,5-lactone 0
                                          alpha-D-Abep-(1->3)-alpha-D-Manp-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-Galp 0
                                          alpha-D-Gal-(1->6)-alpha-D-Gal-(1->6)-beta-D-Glc-(1<->2)-Fru 0
                                          alpha-D-Galp-(1->2)-[alpha-D-Abep-(1->3)]-alpha-D-Manp-(1->4)-alpha-L-Rhap 0
                                          alpha-D-Galp-(1->3)-[alpha-L-Fucp-(1->2)]-beta-D-Galp-(1->3)-beta-D-Galp + 0
                                          alpha-D-Galp-(1->3)-[alpha-L-Fucp-(1->2)]-beta-D-Galp-(1->4)-beta-D-Glcp + 0
                                          alpha-D-Galp-(1->3)-alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                                          alpha-D-Galp-(1->3)-alpha-D-Glcp-(1->3)-alpha-L-Rhap-(1->3)-D-ribitol 0
                                          alpha-D-Galp-(1->3)-alpha-D-Glcp-(1->3)-alpha-L-Rhap-(1->4)-D-ribitol 0
                                          alpha-D-Galp-(1->4)-beta-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-Glcp 0
                                          alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp-(1->4)-beta-D-Glcp 0
                                          alpha-D-Galp-(1->6)-beta-D-Manp-(1->4)-beta-D-Manp-(1->4)-D-Manp 0
                                          alpha-D-GalpA-(1->4)-alpha-D-GalpA-(1->4)-alpha-D-GalpA-(1->4)-alpha-D-GalpA 0
                                          alpha-D-Glcp-(1->3)-alpha-D-Glcp-(1->3)-alpha-L-Rhap-(1->3)-D-ribitol 0
                                          alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->8)-alpha-D-Kdo-(2->4)-alpha-D-Kdo 0
                                          alpha-D-Kdo-(2->8)-[alpha-D-Kdo-(2->4)]-alpha-D-Kdo-(2->4)-alpha-D-Kdo 0
                                          alpha-D-Manp-(1->3)-[alpha-D-Manp-(1->6)]-[beta-D-Xylp-(1->2)]-beta-D-Manp 0
                                          alpha-D-Xyl-(1->3)-beta-D-GlcA-(1->3)-alpha-D-Xyl-(1->3)-beta-D-GlcA 0
                                          alpha-D-Xyl-(1->6)-[alpha-D-Xyl-(1->6)-beta-D-Glc-(->4)]-beta-D-Glc 0
                                          alpha-D-galactosyl-(1->6)-alpha-D-galactosyl-(1->6)-beta-D-fructosyl alpha-D-glucoside 0
                                          alpha-L-Fucp-(1->2)-[alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)]-beta-D-Galp 0
                                          alpha-L-Fucp-(1->2)-beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-D-Glcp + 0
                                          alpha-L-Fucp-(1->3)-[alpha-L-Fucp-(1->2)-beta-D-Galp-(1->4)]-beta-D-Glcp + 0
                                          alpha-L-Rhap-(1->2)-alpha-L-Rhap-(1->3)-alpha-L-Rhap-(1->2)-alpha-L-Rhap 0
                                          alpha-Parp-(1->3)-alpha-D-Manp-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-Galp 0
                                          alpha-Tyvp-(1->3)-alpha-D-Manp-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-Galp 0
                                          arabinotetraose + 0
                                          beta-(1->6)-galactotetraitol 0
                                          beta-D-Delta(4)-GlcpA-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-D-Glcp + 0
                                          beta-D-Galf-(1->5)-beta-D-Galf-(1->6)-alpha-D-Manp-(1->6)-D-Manp 0
                                          beta-D-Galp-(1->4)-[alpha-D-Manp-(1->2)-alpha-D-Manp-(1->2)]-alpha-D-Manp + 0
                                          beta-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                                          beta-D-Galp-(1->6)-beta-D-Galp-(1->4)-beta-D-Galp-(1->3)-L-Man-OH 0
                                          beta-D-Glcp-(1->4)-[alpha-D-GlcpA-(1->3)]-beta-D-Manp-(1->4)-alpha-D-Glcp + 0
                                          beta-D-GlcpA-(1->3)-beta-D-Galp-(1->3)-beta-D-Galp-(1->4)-beta-D-Xylp 0
                                          beta-D-Manp-(1->3)-beta-D-Manp-(1->3)-alpha-L-Rhap-(1->3)-beta-D-Glcp + 0
                                          cyclobis-(1->6)-alpha-nigerosyl 0
                                          galacotetraose + 0
                                          glucotetraose + 0
                                          mannotetraose + 0
                                          stachyose + 4
                                          tetragalacturonic acid hydroxymethylester 0
                                          tetrasaccharide derivative + 15
                                          xylotetraose 0
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