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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tetrasaccharide
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Accession:CHEBI:50126 term browser browse the term
Definition:An oligosaccharide comprising four monomeric monosaccharide units.
Synonyms:related_synonym: tetrasaccharides
 alt_id: CHEBI:26934;   CHEBI:9503
 xref: KEGG:C06768


show annotations for term's descendants           Sort by:
acarbose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE2 angiotensin converting enzyme 2 decreases expression EXP Acarbose results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing increases expression ISO Acarbose results in increased expression of ADIPOQ protein CTD PMID:18290871 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions ISO Acarbose inhibits the reaction [Fructose results in increased expression of CCL2 mRNA]; Acarbose inhibits the reaction [Fructose results in increased expression of CCL2 protein] CTD PMID:17133782 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 decreases expression ISO Acarbose results in decreased expression of CYP2E1 mRNA CTD PMID:14975757 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G FASN fatty acid synthase decreases expression ISO Acarbose results in decreased expression of FASN mRNA; Acarbose results in decreased expression of FASN protein CTD PMID:8101498 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough decreases expression
multiple interactions
decreases secretion
increases secretion
increases response to substance		 ISO Acarbose results in decreased expression of INS1 protein
Acarbose inhibits the reaction [[Dietary Sucrose co-treated with Sodium Chloride, Dietary] results in increased expression of INS1 protein]
Acarbose results in decreased secretion of INS1 protein
Acarbose results in increased secretion of INS1 protein
Acarbose results in increased susceptibility to INS1 protein		 CTD PMID:1767839 PMID:8101498 PMID:9313782 PMID:18290871 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G LEP leptin decreases expression ISO Acarbose results in decreased expression of LEP protein CTD PMID:18290871 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G MGAM maltase-glucoamylase decreases activity EXP
ISO		 Acarbose results in decreased activity of MGAM protein CTD PMID:17585022 PMID:20349118 NCBI chr 7:141,986,518...142,106,747
Ensembl chr 7:141,907,813...142,106,747 		JBrowse link
G NPY neuropeptide Y decreases expression ISO Acarbose results in decreased expression of NPY protein CTD PMID:18290871 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha affects response to substance EXP PPARGC1A protein polymorphism affects the susceptibility to Acarbose CTD PMID:15592662 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 increases expression ISO Acarbose results in increased expression of SLC2A1 protein CTD PMID:11779583 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 increases expression ISO Acarbose results in increased expression of SLC2A4 mRNA; Acarbose results in increased expression of SLC2A4 protein CTD PMID:1767839 NCBI chr17:7,281,718...7,288,257
Ensembl chr17:7,281,718...7,288,257 		JBrowse link
G SQSTM1 sequestosome 1 affects response to substance ISO SQSTM1 affects the susceptibility to Acarbose CTD PMID:19207582 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G TNF tumor necrosis factor decreases expression
multiple interactions		 ISO Acarbose results in decreased expression of TNF mRNA
Acarbose results in decreased expression of TNF mRNA; Acarbose results in decreased expression of TNF protein
Acarbose inhibits the reaction [Oxygen deficiency results in increased expression of TNF mRNA]		 CTD PMID:12717270 PMID:14975757 PMID:20703014 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOS2 nitric oxide synthase 2 multiple interactions ISO ganglioside, GD1b analog inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 results in increased activity of NOS2 protein] which results in increased secretion of Nitrites]; ganglioside, GD1b inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 results in increased activity of NOS2 protein] which results in increased secretion of Nitrites] CTD PMID:31202640 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
verbascose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP verbascose inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of CXCL8 protein] CTD PMID:33130239 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G IFNG interferon gamma multiple interactions EXP [Gallic Acid co-treated with Butyric Acid co-treated with verbascose] affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of IL1B protein]; verbascose affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of IL1B protein]; verbascose inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of CXCL8 protein]; verbascose promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of TNF protein] CTD PMID:33130239 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL1B interleukin 1 beta multiple interactions EXP [Gallic Acid co-treated with Butyric Acid co-treated with verbascose] affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of IL1B protein]; verbascose affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of IL1B protein] CTD PMID:33130239 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G TNF tumor necrosis factor multiple interactions EXP verbascose promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of TNF protein] CTD PMID:33130239 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26439
    chemical entity 26419
      atom 26415
        nonmetal atom 25679
          oxygen atom 24874
            oxygen molecular entity 24874
              organooxygen compound 24131
                carbohydrates and carbohydrate derivatives 16805
                  glycan 9093
                    oligosaccharide 622
                      tetrasaccharide 18
                        1(F)-alpha-D-galactosylraffinose 0
                        1,6-kestotetraose 0
                        2,2'-difucosyllactose 0
                        3'-Sialyl-3-fucosyllactose 0
                        6,6-kestotetraose 0
                        6-C-Me-alpha-D-Manp-(1->2)-alpha-D-Manp-(1->2)-alpha-D-Manp-(1->3)-alpha-D-Manp 0
                        D-cellotetraono-1,5-lactone 0
                        D-maltotetraono-1,5-lactone 0
                        D-xylotetraono-1,5-lactone 0
                        L-alpha-D-Hepp-(1->2)-L-alpha-D-Hepp-(1->3)-[beta-Glcp-(1->4)]-L-alpha-D-Hepp 0
                        L-alpha-D-Hepp-(1->7)-L-alpha-D-Hepp-(1->3)-L-alpha-D-Hepp-(1->5)-alpha-Kdo + 0
                        L-glycero-alpha-D-manno-Hepp-(1->2)-L-glycero-alpha-D-manno-Hepp-(1->3)-L-glycero-alpha-D-manno-Hepp-(1->5)-alpha-Kdo 0
                        Lactodifucotetraose 0
                        N,N',N'',N'''-tetraacetylchitotetraono-1,5-lactone 0
                        alpha-D-Abep-(1->3)-alpha-D-Manp-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-Galp 0
                        alpha-D-Gal-(1->6)-alpha-D-Gal-(1->6)-beta-D-Glc-(1<->2)-Fru 0
                        alpha-D-Galp-(1->2)-[alpha-D-Abep-(1->3)]-alpha-D-Manp-(1->4)-alpha-L-Rhap 0
                        alpha-D-Galp-(1->3)-[alpha-L-Fucp-(1->2)]-beta-D-Galp-(1->3)-beta-D-Galp + 0
                        alpha-D-Galp-(1->3)-[alpha-L-Fucp-(1->2)]-beta-D-Galp-(1->4)-beta-D-Glcp + 0
                        alpha-D-Galp-(1->3)-alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                        alpha-D-Galp-(1->3)-alpha-D-Glcp-(1->3)-alpha-L-Rhap-(1->3)-D-ribitol 0
                        alpha-D-Galp-(1->3)-alpha-D-Glcp-(1->3)-alpha-L-Rhap-(1->4)-D-ribitol 0
                        alpha-D-Galp-(1->4)-beta-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-Glcp 0
                        alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp-(1->4)-beta-D-Glcp 0
                        alpha-D-Galp-(1->6)-beta-D-Manp-(1->4)-beta-D-Manp-(1->4)-D-Manp 0
                        alpha-D-GalpA-(1->4)-alpha-D-GalpA-(1->4)-alpha-D-GalpA-(1->4)-alpha-D-GalpA 0
                        alpha-D-Glcp-(1->3)-alpha-D-Glcp-(1->3)-alpha-L-Rhap-(1->3)-D-ribitol 0
                        alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->8)-alpha-D-Kdo-(2->4)-alpha-D-Kdo 0
                        alpha-D-Kdo-(2->8)-[alpha-D-Kdo-(2->4)]-alpha-D-Kdo-(2->4)-alpha-D-Kdo 0
                        alpha-D-Manp-(1->3)-[alpha-D-Manp-(1->6)]-[beta-D-Xylp-(1->2)]-beta-D-Manp 0
                        alpha-D-Xyl-(1->3)-beta-D-GlcA-(1->3)-alpha-D-Xyl-(1->3)-beta-D-GlcA 0
                        alpha-D-Xyl-(1->6)-[alpha-D-Xyl-(1->6)-beta-D-Glc-(->4)]-beta-D-Glc 0
                        alpha-D-galactosyl-(1->6)-alpha-D-galactosyl-(1->6)-beta-D-fructosyl alpha-D-glucoside 0
                        alpha-L-Fucp-(1->2)-[alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)]-beta-D-Galp 0
                        alpha-L-Fucp-(1->2)-beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-D-Glcp + 0
                        alpha-L-Fucp-(1->3)-[alpha-L-Fucp-(1->2)-beta-D-Galp-(1->4)]-beta-D-Glcp + 0
                        alpha-L-Rhap-(1->2)-alpha-L-Rhap-(1->3)-alpha-L-Rhap-(1->2)-alpha-L-Rhap 0
                        alpha-Parp-(1->3)-alpha-D-Manp-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-Galp 0
                        alpha-Tyvp-(1->3)-alpha-D-Manp-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-Galp 0
                        arabinotetraose + 0
                        beta-(1->6)-galactotetraitol 0
                        beta-D-Delta(4)-GlcpA-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-D-Glcp + 0
                        beta-D-Galf-(1->5)-beta-D-Galf-(1->6)-alpha-D-Manp-(1->6)-D-Manp 0
                        beta-D-Galp-(1->4)-[alpha-D-Manp-(1->2)-alpha-D-Manp-(1->2)]-alpha-D-Manp + 0
                        beta-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                        beta-D-Galp-(1->6)-beta-D-Galp-(1->4)-beta-D-Galp-(1->3)-L-Man-OH 0
                        beta-D-Glcp-(1->4)-[alpha-D-GlcpA-(1->3)]-beta-D-Manp-(1->4)-alpha-D-Glcp + 0
                        beta-D-GlcpA-(1->3)-beta-D-Galp-(1->3)-beta-D-Galp-(1->4)-beta-D-Xylp 0
                        beta-D-Manp-(1->3)-beta-D-Manp-(1->3)-alpha-L-Rhap-(1->3)-beta-D-Glcp + 0
                        cyclobis-(1->6)-alpha-nigerosyl 0
                        galacotetraose + 0
                        glucotetraose + 0
                        mannotetraose + 0
                        stachyose + 4
                        tetragalacturonic acid hydroxymethylester 0
                        tetrasaccharide derivative + 15
                        xylotetraose 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26439
    subatomic particle 26415
      composite particle 26415
        hadron 26415
          baryon 26415
            nucleon 26415
              atomic nucleus 26415
                atom 26415
                  main group element atom 26161
                    p-block element atom 26161
                      carbon group element atom 25598
                        carbon atom 25560
                          organic molecular entity 25560
                            heteroorganic entity 24948
                              organochalcogen compound 24542
                                organooxygen compound 24131
                                  carbohydrates and carbohydrate derivatives 16805
                                    carbohydrate 16805
                                      oligosaccharide 622
                                        tetrasaccharide 18
                                          1(F)-alpha-D-galactosylraffinose 0
                                          1,6-kestotetraose 0
                                          2,2'-difucosyllactose 0
                                          3'-Sialyl-3-fucosyllactose 0
                                          6,6-kestotetraose 0
                                          6-C-Me-alpha-D-Manp-(1->2)-alpha-D-Manp-(1->2)-alpha-D-Manp-(1->3)-alpha-D-Manp 0
                                          D-cellotetraono-1,5-lactone 0
                                          D-maltotetraono-1,5-lactone 0
                                          D-xylotetraono-1,5-lactone 0
                                          L-alpha-D-Hepp-(1->2)-L-alpha-D-Hepp-(1->3)-[beta-Glcp-(1->4)]-L-alpha-D-Hepp 0
                                          L-alpha-D-Hepp-(1->7)-L-alpha-D-Hepp-(1->3)-L-alpha-D-Hepp-(1->5)-alpha-Kdo + 0
                                          L-glycero-alpha-D-manno-Hepp-(1->2)-L-glycero-alpha-D-manno-Hepp-(1->3)-L-glycero-alpha-D-manno-Hepp-(1->5)-alpha-Kdo 0
                                          Lactodifucotetraose 0
                                          N,N',N'',N'''-tetraacetylchitotetraono-1,5-lactone 0
                                          alpha-D-Abep-(1->3)-alpha-D-Manp-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-Galp 0
                                          alpha-D-Gal-(1->6)-alpha-D-Gal-(1->6)-beta-D-Glc-(1<->2)-Fru 0
                                          alpha-D-Galp-(1->2)-[alpha-D-Abep-(1->3)]-alpha-D-Manp-(1->4)-alpha-L-Rhap 0
                                          alpha-D-Galp-(1->3)-[alpha-L-Fucp-(1->2)]-beta-D-Galp-(1->3)-beta-D-Galp + 0
                                          alpha-D-Galp-(1->3)-[alpha-L-Fucp-(1->2)]-beta-D-Galp-(1->4)-beta-D-Glcp + 0
                                          alpha-D-Galp-(1->3)-alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                                          alpha-D-Galp-(1->3)-alpha-D-Glcp-(1->3)-alpha-L-Rhap-(1->3)-D-ribitol 0
                                          alpha-D-Galp-(1->3)-alpha-D-Glcp-(1->3)-alpha-L-Rhap-(1->4)-D-ribitol 0
                                          alpha-D-Galp-(1->4)-beta-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-Glcp 0
                                          alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp-(1->4)-beta-D-Glcp 0
                                          alpha-D-Galp-(1->6)-beta-D-Manp-(1->4)-beta-D-Manp-(1->4)-D-Manp 0
                                          alpha-D-GalpA-(1->4)-alpha-D-GalpA-(1->4)-alpha-D-GalpA-(1->4)-alpha-D-GalpA 0
                                          alpha-D-Glcp-(1->3)-alpha-D-Glcp-(1->3)-alpha-L-Rhap-(1->3)-D-ribitol 0
                                          alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->8)-alpha-D-Kdo-(2->4)-alpha-D-Kdo 0
                                          alpha-D-Kdo-(2->8)-[alpha-D-Kdo-(2->4)]-alpha-D-Kdo-(2->4)-alpha-D-Kdo 0
                                          alpha-D-Manp-(1->3)-[alpha-D-Manp-(1->6)]-[beta-D-Xylp-(1->2)]-beta-D-Manp 0
                                          alpha-D-Xyl-(1->3)-beta-D-GlcA-(1->3)-alpha-D-Xyl-(1->3)-beta-D-GlcA 0
                                          alpha-D-Xyl-(1->6)-[alpha-D-Xyl-(1->6)-beta-D-Glc-(->4)]-beta-D-Glc 0
                                          alpha-D-galactosyl-(1->6)-alpha-D-galactosyl-(1->6)-beta-D-fructosyl alpha-D-glucoside 0
                                          alpha-L-Fucp-(1->2)-[alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)]-beta-D-Galp 0
                                          alpha-L-Fucp-(1->2)-beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-D-Glcp + 0
                                          alpha-L-Fucp-(1->3)-[alpha-L-Fucp-(1->2)-beta-D-Galp-(1->4)]-beta-D-Glcp + 0
                                          alpha-L-Rhap-(1->2)-alpha-L-Rhap-(1->3)-alpha-L-Rhap-(1->2)-alpha-L-Rhap 0
                                          alpha-Parp-(1->3)-alpha-D-Manp-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-Galp 0
                                          alpha-Tyvp-(1->3)-alpha-D-Manp-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-Galp 0
                                          arabinotetraose + 0
                                          beta-(1->6)-galactotetraitol 0
                                          beta-D-Delta(4)-GlcpA-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-D-Glcp + 0
                                          beta-D-Galf-(1->5)-beta-D-Galf-(1->6)-alpha-D-Manp-(1->6)-D-Manp 0
                                          beta-D-Galp-(1->4)-[alpha-D-Manp-(1->2)-alpha-D-Manp-(1->2)]-alpha-D-Manp + 0
                                          beta-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                                          beta-D-Galp-(1->6)-beta-D-Galp-(1->4)-beta-D-Galp-(1->3)-L-Man-OH 0
                                          beta-D-Glcp-(1->4)-[alpha-D-GlcpA-(1->3)]-beta-D-Manp-(1->4)-alpha-D-Glcp + 0
                                          beta-D-GlcpA-(1->3)-beta-D-Galp-(1->3)-beta-D-Galp-(1->4)-beta-D-Xylp 0
                                          beta-D-Manp-(1->3)-beta-D-Manp-(1->3)-alpha-L-Rhap-(1->3)-beta-D-Glcp + 0
                                          cyclobis-(1->6)-alpha-nigerosyl 0
                                          galacotetraose + 0
                                          glucotetraose + 0
                                          mannotetraose + 0
                                          stachyose + 4
                                          tetragalacturonic acid hydroxymethylester 0
                                          tetrasaccharide derivative + 15
                                          xylotetraose 0
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