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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:estrogen
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Accession:CHEBI:50114 term browser browse the term
Definition:A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens.
Synonyms:related_synonym: Estrogene;   estrogenes;   estrogenes Hormon;   estrogeno;   estrogenos;   estrogens;   oestrogen;   oestrogene;   oestrogenes;   oestrogens
 xref: Wikipedia:Estrogen



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  • Term paths to the root
    Path 1
    Term Annotations click to browse term
      CHEBI ontology 19863
        role 19835
          biological role 19833
            molecular messenger 18650
              hormone 18495
                sex hormone 18316
                  estrogen 18271
                    (10R,13S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one 0
                    (13S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one 0
                    (13S,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol 0
                    (13S,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol 0
                    (13S,17R)-17-hydroxy-13-methyl-17-prop-2-enyl-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one 0
                    (13S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                    (7R,8S,9S,13S,14R,17S)-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                    (8R,9S,13S,14R)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one 0
                    (8R,9S,13S,14R,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol 0
                    (8R,9S,13S,14R,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol 0
                    (8S,13S,14R,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one 0
                    13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol 0
                    13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                    13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                    16alpha-hydroxyestrone + 0
                    16beta-hydroxyestrone 0
                    17-epiestriol + 0
                    17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol 0
                    17alpha-estradiol + 1
                    17alpha-ethynylestradiol 3-sulfate 0
                    17beta-estradiol + 11307
                    2-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                    3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one 0
                    4-hydroxyestrone + 5
                    4-methoxy-17beta-estradiol + 1
                    4-methoxyestrone + 0
                    7alpha-hydroxydehydroepiandrosterone 0
                    7beta-hydroxydehydroepiandrosterone 0
                    Normethandrolone 0
                    estetrol 0
                    estra-1,3,5(10)-trien-3-ol 3
                    estradiol + 11307
                    estriol + 126
                    estriol 3-O-(beta-D-glucuronide) 1
                    estrone + 128
                    gestodene 26
                    mycoestrogen + 733
                    norgestrienone 0
                    oxabolone 0
                    phytoestrogen + 7886
                    xenoestrogen + 18049
    Path 2
    Term Annotations click to browse term
      CHEBI ontology 19863
        role 19835
          biological role 19833
            pharmacological role 19071
              agonist 18611
                hormone 18495
                  sex hormone 18316
                    estrogen 18271
                      (10R,13S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one 0
                      (13S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one 0
                      (13S,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol 0
                      (13S,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol 0
                      (13S,17R)-17-hydroxy-13-methyl-17-prop-2-enyl-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one 0
                      (13S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                      (7R,8S,9S,13S,14R,17S)-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                      (8R,9S,13S,14R)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one 0
                      (8R,9S,13S,14R,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol 0
                      (8R,9S,13S,14R,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol 0
                      (8S,13S,14R,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one 0
                      13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol 0
                      13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                      13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                      16alpha-hydroxyestrone + 0
                      16beta-hydroxyestrone 0
                      17-epiestriol + 0
                      17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol 0
                      17alpha-estradiol + 1
                      17alpha-ethynylestradiol 3-sulfate 0
                      17beta-estradiol + 11307
                      2-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 0
                      3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one 0
                      4-hydroxyestrone + 5
                      4-methoxy-17beta-estradiol + 1
                      4-methoxyestrone + 0
                      7alpha-hydroxydehydroepiandrosterone 0
                      7beta-hydroxydehydroepiandrosterone 0
                      Normethandrolone 0
                      estetrol 0
                      estra-1,3,5(10)-trien-3-ol 3
                      estradiol + 11307
                      estriol + 126
                      estriol 3-O-(beta-D-glucuronide) 1
                      estrone + 128
                      gestodene 26
                      mycoestrogen + 733
                      norgestrienone 0
                      oxabolone 0
                      phytoestrogen + 7886
                      xenoestrogen + 18049
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