CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: (4-chloro-2-methylphenoxy)acetic acid
Accession: CHEBI:50099
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Definition: A chlorophenoxyacetic acid that is (4-chlorophenoxy)acetic acid substituted by a methyl group at position 2.
Synonyms: related_synonym: (2-Methyl-4-chlorophenoxy)acetic acid; 2,4-MCPA; 2-Methyl-4-chlorophenoxyacetic acid; 2-Methyl-4-chlorphenoxyessigsaeure; Agroxone; Formula=C9H9ClO3; InChI=1S/C9H9ClO3/c1-6-4-7(10)2-3-8(6)13-5-9(11)12/h2-4H,5H2,1H3,(H,11,12); InChIKey=WHKUVVPPKQRRBV-UHFFFAOYSA-N; MCP; MCPA; SMILES=Cc1cc(Cl)ccc1OCC(O)=O; [(4-Chloro-o-tolyl)oxy]acetic acid
xref: Beilstein:2051752; CAS:94-74-6; KEGG:C18528
xref_mesh: MESH:D008456
xref: PMID:15669026; PPDB:427; Patent:GB573479; Patent:GB573510; Patent:US274810; Pesticides:mcpa; Reaxys:2051752; Wikipedia:MCPA
G
Clcnka
chloride voltage-gated channel Ka
decreases activity
EXP
2-Methyl-4-chlorophenoxyacetic Acid analog results in decreased activity of CLCNKA protein
CTD
PMID:15167890
NCBI chr 5:153,691,208...153,706,295
Ensembl chr 5:153,691,209...153,706,148
G
Clcnkb
chloride voltage-gated channel Kb
decreases activity
EXP
2-Methyl-4-chlorophenoxyacetic Acid analog results in decreased activity of CLCNKB protein
CTD
PMID:15167890
NCBI chr 5:153,710,086...153,733,162
Ensembl chr 5:153,710,094...153,732,153
G
Slc1a2
solute carrier family 1 member 2
affects expression
EXP
2-Methyl-4-chlorophenoxyacetic Acid affects the expression of SLC1A2 protein
CTD
PMID:16019039
NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498
G
Tnf
tumor necrosis factor
increases expression
ISO
2-Methyl-4-chlorophenoxyacetic Acid results in increased expression of TNF protein
CTD
PMID:10883730
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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