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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:glycosyloxyflavone
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Accession:CHEBI:50018 term browser browse the term
Definition:A member of the class of flavones having one or more glycosyl residues attached at unspecified positions.
Synonyms:related_synonym: flavone glycoside;   flavone glycosides;   glycosyloxyflavones


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afzelin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MITF melanocyte inducing transcription factor increases expression EXP afzelin results in increased expression of MITF mRNA; afzelin results in increased expression of MITF protein CTD PMID:27287415 NCBI chr 3:69,739,464...69,968,332
Ensembl chr 3:69,739,456...69,968,336 		JBrowse link
G TYR tyrosinase multiple interactions
increases expression		 EXP afzelin results in increased expression of and results in increased activity of TYR protein
afzelin results in increased expression of TYR mRNA		 CTD PMID:27287415 NCBI chr11:89,177,875...89,295,759
Ensembl chr11:89,177,875...89,295,759 		JBrowse link
G TYRP1 tyrosinase related protein 1 increases expression EXP afzelin results in increased expression of TYRP1 mRNA; afzelin results in increased expression of TYRP1 protein CTD PMID:27287415 NCBI chr 9:12,693,385...12,710,285
Ensembl chr 9:12,685,439...12,710,285 		JBrowse link
apigenin 7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GYPA glycophorin A (MNS blood group) increases expression EXP apigetrin results in increased expression of GYPA protein CTD PMID:25058688 NCBI chr 4:144,109,303...144,140,718
Ensembl chr 4:144,109,303...144,140,751 		JBrowse link
baicalin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Yt blood group) multiple interactions
increases expression		 ISO baicalin results in increased expression of and results in increased activity of ACHE protein
baicalin results in increased expression of ACHE mRNA		 CTD PMID:27019979 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G AHR aryl hydrocarbon receptor increases activity ISO
EXP		 baicalin results in increased activity of AHR protein CTD PMID:17869316 PMID:26204831 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G AIF1 allograft inflammatory factor 1 multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of AIF1 protein] CTD PMID:38016618 NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase multiple interactions ISO baicalin inhibits the reaction [Hydrogen Peroxide affects the localization of and results in increased activity of ALOX5 protein] CTD PMID:20139896 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G ANGPT1 angiopoietin 1 multiple interactions ISO baicalin inhibits the reaction [Streptozocin results in decreased expression of ANGPT1 mRNA] CTD PMID:34414639 NCBI chr 8:107,249,482...107,497,918
Ensembl chr 8:107,249,482...107,498,055 		JBrowse link
G ATF2 activating transcription factor 2 multiple interactions ISO baicalin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of ATF2 protein] CTD PMID:24312512 NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 EXP
ISO		 baicalin results in increased expression of BAX protein
baicalin affects the reaction [Rotenone results in increased expression of BAX mRNA]; baicalin inhibits the reaction [Rotenone results in increased expression of BAX protein]
baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; baicalin inhibits the reaction [Gentamicins results in increased expression of BAX mRNA]; baicalin inhibits the reaction [Gentamicins results in increased expression of BAX protein]
baicalin inhibits the reaction [Rotenone affects the expression of BAX protein]		 CTD PMID:21457722 PMID:25423838 PMID:31021006 PMID:34333357 PMID:36446982 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression		 ISO
EXP		 baicalin inhibits the reaction [Rotenone affects the expression of BCL2 protein]
baicalin affects the reaction [Rotenone results in decreased expression of BCL2 mRNA]; baicalin inhibits the reaction [Rotenone results in decreased expression of BCL2 protein]
baicalin results in decreased expression of BCL2 protein
baicalin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; baicalin inhibits the reaction [Gentamicins results in decreased expression of BCL2 mRNA]; baicalin inhibits the reaction [Gentamicins results in decreased expression of BCL2 protein]		 CTD PMID:25423838 PMID:31021006 PMID:34333357 PMID:36446982 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CASP1 caspase 1 multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of CASP1 protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]] CTD PMID:38016618 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CASP3 caspase 3 multiple interactions ISO
EXP		 baicalin inhibits the reaction [Rotenone affects the expression of CASP3 protein]
baicalin affects the reaction [Rotenone results in decreased activity of CASP3 protein]
baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; baicalin inhibits the reaction [Gentamicins results in increased cleavage of CASP3 protein]		 CTD PMID:25423838 PMID:31021006 PMID:34333357 PMID:36446982 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CAT catalase multiple interactions ISO baicalin inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein] CTD PMID:34333357 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCNA2 cyclin A2 decreases expression EXP baicalin results in decreased expression of CCNA2 protein CTD PMID:21457722 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883 		JBrowse link
G CCND1 cyclin D1 increases expression
decreases expression
multiple interactions		 EXP baicalin results in increased expression of CCND1 mRNA
baicalin results in decreased expression of CCND1 protein
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of CCND1 mRNA]		 CTD PMID:19160421 PMID:21457722 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G COL1A2 collagen type I alpha 2 chain multiple interactions ISO baicalin inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA] CTD PMID:19474275 NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions
increases expression		 EXP 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A1 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A1 protein]; baicalin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
baicalin results in increased expression of CYP1A1 mRNA; baicalin results in increased expression of CYP1A1 protein		 CTD PMID:18451504 PMID:26204831 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 multiple interactions
increases expression		 EXP
ISO		 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A2 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A2 protein]
resveratrol inhibits the reaction [baicalin results in increased expression of CYP1A2 mRNA]; resveratrol inhibits the reaction [baicalin results in increased expression of CYP1A2 protein]
baicalin results in increased expression of CYP1A2 mRNA; baicalin results in increased expression of CYP1A2 protein		 CTD PMID:26204831 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G EGF epidermal growth factor multiple interactions EXP baicalin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; baicalin inhibits the reaction [EGF protein results in increased phosphorylation of ELK1 protein] CTD PMID:25625231 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGFR epidermal growth factor receptor multiple interactions EXP baicalin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G ELK1 ETS transcription factor ELK1 multiple interactions EXP baicalin inhibits the reaction [EGF protein results in increased phosphorylation of ELK1 protein] CTD PMID:25625231 NCBI chr  X:47,635,520...47,650,604
Ensembl chr  X:47,635,521...47,650,604 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO baicalin inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:29031535 NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819 		JBrowse link
G FOXA2 forkhead box A2 decreases expression EXP baicalin results in decreased expression of FOXA2 mRNA; baicalin results in decreased expression of FOXA2 protein CTD PMID:32687838 NCBI chr20:22,580,998...22,585,490
Ensembl chr20:22,580,998...22,585,455 		JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 multiple interactions ISO baicalin inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GOT1 protein] CTD PMID:15645217 NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624 		JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO baicalin inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GPT protein] CTD PMID:15645217 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G HES1 hes family bHLH transcription factor 1 increases expression
multiple interactions		 EXP baicalin results in increased expression of HES1 mRNA
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HES1 mRNA]		 CTD PMID:19160421 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732 		JBrowse link
G HEY1 hes related family bHLH transcription factor with YRPW motif 1 increases expression
multiple interactions		 EXP baicalin results in increased expression of HEY1 mRNA
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HEY1 mRNA]		 CTD PMID:19160421 NCBI chr 8:79,764,010...79,767,767
Ensembl chr 8:79,762,371...79,767,857 		JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 multiple interactions
increases expression		 EXP N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HEY2 mRNA] CTD PMID:19160421 NCBI chr 6:125,749,632...125,761,269
Ensembl chr 6:125,747,664...125,761,269 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
increases expression		 ISO [baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein; baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of HMOX1 protein]; baicalin promotes the reaction [Carbon Tetrachloride results in increased expression of HMOX1 mRNA]; baicalin promotes the reaction [Carbon Tetrachloride results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [[baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein]
baicalin results in increased expression of HMOX1 mRNA; baicalin results in increased expression of HMOX1 protein		 CTD PMID:16824337 PMID:18187930 PMID:38016618 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HNF1A HNF1 homeobox A decreases expression
multiple interactions		 EXP
ISO		 baicalin results in decreased expression of HNF1A mRNA; baicalin results in decreased expression of HNF1A protein
baicalin inhibits the reaction [HNF4A protein binds to HNF1A promoter]; HNF1A protein promotes the reaction [baicalin results in decreased secretion of Hepatitis B Surface Antigens]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A mRNA]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A protein]		 CTD PMID:32687838 NCBI chr12:120,978,543...121,002,512
Ensembl chr12:120,978,543...121,002,512 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha decreases expression
multiple interactions		 ISO
EXP		 baicalin results in decreased expression of HNF4A protein
baicalin inhibits the reaction [HNF4A protein binds to HNF1A promoter]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A mRNA]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A protein]; HNF4A protein promotes the reaction [baicalin results in decreased secretion of Hepatitis B Surface Antigens]
baicalin results in decreased expression of HNF4A mRNA; baicalin results in decreased expression of HNF4A protein		 CTD PMID:32687838 NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 multiple interactions ISO baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of HSPB1 protein] CTD PMID:34414639 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO
EXP		 baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B mRNA]; baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]; baicalin inhibits the reaction [Palmitic Acid results in increased secretion of IL1B protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]]
baicalin inhibits the reaction [Rotenone results in increased expression of IL1B protein]		 CTD PMID:29031535 PMID:36446982 PMID:38016618 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 decreases expression
multiple interactions		 ISO baicalin results in decreased expression of IL6 mRNA; baicalin results in decreased expression of IL6 protein
baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL6 mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL6 mRNA]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 protein]; baicalin inhibits the reaction [Palmitic Acid results in increased secretion of IL6 protein]		 CTD PMID:22019745 PMID:29031535 PMID:34333357 PMID:38016618 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO baicalin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein] CTD PMID:34414639 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of KEAP1 protein]; baicalin promotes the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in decreased expression of KEAP1 protein] CTD PMID:38016618 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein] CTD PMID:34414639 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein] CTD PMID:34414639 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor decreases expression ISO baicalin results in decreased expression of MYD88 protein CTD PMID:22019745 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] affects the localization of NFE2L2 protein; baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of NFE2L2 protein]; baicalin inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased ubiquitination of NFE2L2 protein]; baicalin promotes the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein]; baicalin promotes the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [[baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]] CTD PMID:38016618 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKBIA NFKB inhibitor alpha increases expression ISO baicalin results in increased expression of NFKBIA protein CTD PMID:22019745 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of NLRP3 protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]; baicalin inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]] CTD PMID:29031535 PMID:38016618 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
decreases expression		 ISO baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 mRNA]; baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein]
baicalin results in decreased expression of NOS2 mRNA; baicalin results in decreased expression of NOS2 protein
baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; mifobate inhibits the reaction [baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]]		 CTD PMID:18187930 PMID:22019745 PMID:24312512 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOTCH1 notch receptor 1 increases activity
increases expression		 EXP baicalin results in increased activity of NOTCH1 protein
baicalin results in increased expression of NOTCH1 mRNA		 CTD PMID:19160421 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 increases expression EXP Baicalin increases expression of NR1H3 mRNA and protein in foam cells RGD PMID:27389392 RGD:401842390 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033 		JBrowse link
G PKM pyruvate kinase M1/2 increases activity EXP baicalin results in increased activity of PKM protein CTD PMID:25388478 NCBI chr15:72,199,029...72,231,591
Ensembl chr15:72,199,029...72,231,819 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions ISO baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of and results in decreased activity of PPARG protein] CTD PMID:24312512 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PRIMA1 proline rich membrane anchor 1 increases expression ISO baicalin results in increased expression of PRIMA1 mRNA CTD PMID:27019979 NCBI chr14:93,718,298...93,788,994
Ensembl chr14:93,718,298...93,788,485 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 decreases expression ISO baicalin results in decreased expression of PTGS2 mRNA; baicalin results in decreased expression of PTGS2 protein CTD PMID:22019745 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PYCARD PYD and CARD domain containing multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of PYCARD protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]] CTD PMID:38016618 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO baicalin affects the localization of and results in decreased expression of RELA protein
baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased phosphorylation of RELA protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased phosphorylation of RELA protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]]		 CTD PMID:22019745 PMID:34333357 PMID:38016618 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G SNCA synuclein alpha multiple interactions ISO [baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] affects the localization of NFE2L2 protein; [baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL6 mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of TNF mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]; baicalin inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased ubiquitination of NFE2L2 protein]; baicalin promotes the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in decreased expression of KEAP1 protein]; baicalin promotes the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein]; baicalin promotes the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [[baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]] CTD PMID:38016618 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
G TEK TEK receptor tyrosine kinase multiple interactions ISO baicalin inhibits the reaction [Streptozocin results in decreased expression of TEK mRNA] CTD PMID:34414639 NCBI chr 9:27,109,141...27,230,178
Ensembl chr 9:27,109,141...27,230,174 		JBrowse link
G TFAM transcription factor A, mitochondrial multiple interactions
decreases expression		 EXP baicalin inhibits the reaction [Rotenone results in decreased expression of TFAM mRNA]
baicalin results in decreased expression of TFAM mRNA		 CTD PMID:36446982 NCBI chr10:58,385,410...58,399,220
Ensembl chr10:58,385,345...58,399,220 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions ISO baicalin inhibits the reaction [Streptozocin results in decreased expression of TGFB1 mRNA]; baicalin inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA] CTD PMID:19474275 PMID:34414639 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TH tyrosine hydroxylase multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TH protein] CTD PMID:38016618 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G TLR4 toll like receptor 4 decreases expression
multiple interactions		 ISO baicalin results in decreased expression of TLR4 protein
baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of TLR4 protein]
baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]		 CTD PMID:22019745 PMID:24312512 PMID:34333357 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TNF tumor necrosis factor multiple interactions
decreases expression		 ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TNF mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of TNF mRNA]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of TNF protein]; baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]; baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]
baicalin results in decreased expression of TNF mRNA; baicalin results in decreased expression of TNF protein
baicalin inhibits the reaction [Paraquat results in increased expression of TNF protein]		 CTD PMID:16824337 PMID:18187930 PMID:22019745 PMID:34333357 PMID:38016618 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TP53 tumor protein p53 increases expression EXP baicalin results in increased expression of TP53 protein CTD PMID:21457722 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G TXNIP thioredoxin interacting protein multiple interactions ISO baicalin inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein]; dorsomorphin inhibits the reaction [baicalin inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein]] CTD PMID:29031535 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579 		JBrowse link
G USP27X ubiquitin specific peptidase 27 X-linked multiple interactions ISO baicalin inhibits the reaction [Streptozocin results in increased expression of USP27X protein] CTD PMID:34414639 NCBI chr  X:49,879,484...49,882,558
Ensembl chr  X:49,879,484...49,882,558 		JBrowse link
G VEGFC vascular endothelial growth factor C multiple interactions ISO baicalin inhibits the reaction [Streptozocin results in decreased expression of VEGFC mRNA] CTD PMID:34414639 NCBI chr 4:176,683,538...176,792,922
Ensembl chr 4:176,683,538...176,792,922 		JBrowse link
G XDH xanthine dehydrogenase multiple interactions ISO baicalin inhibits the reaction [[Biological Products co-treated with potassium oxonate] results in increased activity of XDH protein] CTD PMID:34044073 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
diosmin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor multiple interactions ISO
EXP		 Diosmin binds to and results in increased activity of AHR protein CTD PMID:14644660 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G BAD BCL2 associated agonist of cell death multiple interactions ISO Diosmin inhibits the reaction [Lipopolysaccharides results in increased expression of BAD protein] CTD PMID:21477647 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO Diosmin inhibits the reaction [Benzo(a)pyrene results in increased expression of BAX protein] CTD PMID:32061149 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions ISO [Diosmin co-treated with Lipopolysaccharides] results in increased expression of BCL2 protein
Diosmin inhibits the reaction [Benzo(a)pyrene results in decreased expression of BCL2 protein]		 CTD PMID:21477647 PMID:32061149 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CASP3 caspase 3 multiple interactions ISO Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of CASP3 protein]; Diosmin inhibits the reaction [Acetic Acid results in increased expression of CASP3 protein]; Diosmin inhibits the reaction [Lipopolysaccharides results in increased activity of CASP3 protein]
Diosmin inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]		 CTD PMID:21477647 PMID:23665045 PMID:29187079 PMID:32061149 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP7 caspase 7 multiple interactions ISO Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of CASP7 protein] CTD PMID:23665045 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907 		JBrowse link
G CASP9 caspase 9 multiple interactions ISO Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of CASP9 protein] CTD PMID:23665045 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase multiple interactions ISO Diosmin inhibits the reaction [2-Acetylaminofluorene results in decreased expression of CAT protein]; Diosmin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein] CTD PMID:22056647 PMID:23665045 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 multiple interactions ISO Diosmin inhibits the reaction [Benzo(a)pyrene results in increased expression of CEACAM1 protein] CTD PMID:35920545 NCBI chr19:42,507,306...42,528,481
Ensembl chr19:42,507,304...42,561,234 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions ISO Diosmin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of CREB1 protein] CTD PMID:35920545 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions ISO Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of CYP2E1 protein] CTD PMID:23665045 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G ENO2 enolase 2 multiple interactions ISO Diosmin inhibits the reaction [Benzo(a)pyrene results in increased expression of ENO2 protein] CTD PMID:35920545 NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698 		JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions ISO Diosmin inhibits the reaction [Benzo(a)pyrene results in decreased expression of and results in decreased activity of GPX1 protein] CTD PMID:35920545 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GSR glutathione-disulfide reductase multiple interactions ISO Diosmin inhibits the reaction [2-Acetylaminofluorene results in decreased expression of GSR protein]
Diosmin inhibits the reaction [Benzo(a)pyrene results in decreased expression of GSR protein]		 CTD PMID:23665045 PMID:32061149 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO Diosmin inhibits the reaction [Benzo(a)pyrene results in increased expression of IL6 protein] CTD PMID:32061149 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G MKI67 marker of proliferation Ki-67 multiple interactions ISO Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of MKI67 protein]; Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of MKI67 protein] CTD PMID:23665045 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G MPO myeloperoxidase multiple interactions ISO Diosmin inhibits the reaction [Acetic Acid results in increased activity of MPO protein] CTD PMID:29187079 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of NOS2 protein] CTD PMID:23665045 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions ISO Diosmin inhibits the reaction [Benzo(a)pyrene results in increased cleavage of PARP1 protein] CTD PMID:32061149 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions ISO Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of PCNA protein]; Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of PCNA protein] CTD PMID:23665045 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626 		JBrowse link
G PTGER2 prostaglandin E receptor 2 multiple interactions ISO Diosmin inhibits the reaction [Benzo(a)pyrene results in increased expression of PTGER2 protein] CTD PMID:35920545 NCBI chr14:52,314,312...52,328,598
Ensembl chr14:52,314,305...52,328,598 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of PTGS2 protein]; Diosmin inhibits the reaction [Acetic Acid results in increased expression of PTGS2 protein]
Diosmin inhibits the reaction [Benzo(a)pyrene results in increased expression of PTGS2 protein]		 CTD PMID:23665045 PMID:29187079 PMID:32061149 PMID:35920545 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO Diosmin inhibits the reaction [Benzo(a)pyrene results in increased expression of RELA protein] CTD PMID:32061149 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of TNF protein]; Diosmin inhibits the reaction [Acetic Acid results in increased expression of TNF protein]; Diosmin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:21477647 PMID:23665045 PMID:29187079 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TP53 tumor protein p53 multiple interactions ISO Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TP53 protein] CTD PMID:23665045 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G XDH xanthine dehydrogenase multiple interactions ISO Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of XDH protein]
Diosmin inhibits the reaction [Benzo(a)pyrene results in increased expression of XDH protein]		 CTD PMID:23665045 PMID:32061149 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
gossypin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF1 activating transcription factor 1 multiple interactions
decreases phosphorylation		 ISO
EXP		 gossypin inhibits the reaction [EGF protein results in increased phosphorylation of ATF1 protein]
gossypin results in decreased phosphorylation of ATF1 protein		 CTD PMID:30536456 NCBI chr12:50,763,459...50,821,162
Ensembl chr12:50,763,710...50,821,162 		JBrowse link
G AURKA aurora kinase A multiple interactions EXP gossypin binds to and results in decreased activity of AURKA protein CTD PMID:30536456 NCBI chr20:56,369,390...56,392,215
Ensembl chr20:56,369,389...56,392,337 		JBrowse link
G BCL2L1 BCL2 like 1 decreases expression EXP gossypin results in decreased expression of BCL2L1 protein CTD PMID:30536456 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G CASP3 caspase 3 increases cleavage EXP gossypin results in increased cleavage of CASP3 protein CTD PMID:30536456 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP7 caspase 7 increases cleavage EXP gossypin results in increased cleavage of CASP7 protein CTD PMID:30536456 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907 		JBrowse link
G CASP9 caspase 9 increases cleavage EXP gossypin results in increased cleavage of CASP9 protein CTD PMID:30536456 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase multiple interactions ISO gossypin inhibits the reaction [Lipopolysaccharides results in decreased expression of CAT protein]; gossypin inhibits the reaction [Oleic Acid results in increased activity of CAT protein] CTD PMID:37148149 PMID:37696682 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCNA2 cyclin A2 decreases expression EXP gossypin results in decreased expression of CCNA2 protein CTD PMID:30536456 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883 		JBrowse link
G CCNB1 cyclin B1 decreases expression EXP gossypin results in decreased expression of CCNB1 protein CTD PMID:30536456 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245 		JBrowse link
G CDK1 cyclin dependent kinase 1 decreases phosphorylation EXP gossypin results in decreased phosphorylation of CDK1 protein CTD PMID:30536456 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852 		JBrowse link
G CRP C-reactive protein multiple interactions ISO gossypin inhibits the reaction [Lipopolysaccharides results in increased expression of CRP protein] CTD PMID:37148149 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G EGF epidermal growth factor multiple interactions ISO gossypin inhibits the reaction [EGF protein results in increased phosphorylation of ATF1 protein] CTD PMID:30536456 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO gossypin inhibits the reaction [Lipopolysaccharides results in decreased expression of HMOX1 protein] CTD PMID:37148149 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G IL10 interleukin 10 multiple interactions ISO gossypin inhibits the reaction [Lipopolysaccharides results in decreased expression of IL10 protein] CTD PMID:37148149 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL13 interleukin 13 multiple interactions ISO gossypin inhibits the reaction [Lipopolysaccharides results in increased expression of IL13 protein] CTD PMID:37148149 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL17A interleukin 17A multiple interactions ISO gossypin inhibits the reaction [Lipopolysaccharides results in increased expression of IL17A protein] CTD PMID:37148149 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL18 interleukin 18 multiple interactions ISO gossypin inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 protein] CTD PMID:37148149 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO gossypin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; gossypin inhibits the reaction [Oleic Acid results in increased expression of IL1B mRNA] CTD PMID:37148149 PMID:37696682 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL4 interleukin 4 multiple interactions ISO gossypin inhibits the reaction [Lipopolysaccharides results in decreased expression of IL4 protein] CTD PMID:37148149 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL5 interleukin 5 multiple interactions ISO gossypin inhibits the reaction [Lipopolysaccharides results in increased expression of IL5 protein] CTD PMID:37148149 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO gossypin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; gossypin inhibits the reaction [Oleic Acid results in increased expression of IL6 mRNA] CTD PMID:37148149 PMID:37696682 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit decreases phosphorylation EXP gossypin results in decreased phosphorylation of JUN protein CTD PMID:30536456 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G MPO myeloperoxidase multiple interactions ISO gossypin inhibits the reaction [Lipopolysaccharides results in increased expression of MPO protein] CTD PMID:37148149 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions ISO gossypin inhibits the reaction [Lipopolysaccharides results in decreased expression of NFE2L2 protein] CTD PMID:37148149 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 increases cleavage EXP gossypin results in increased cleavage of PARP1 protein CTD PMID:30536456 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO gossypin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:37148149 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RPS6KA3 ribosomal protein S6 kinase A3 multiple interactions EXP gossypin binds to and results in decreased activity of RPS6KA3 protein CTD PMID:30536456 NCBI chr  X:20,149,911...20,267,097
Ensembl chr  X:20,149,911...20,267,519 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions ISO gossypin inhibits the reaction [Lipopolysaccharides results in increased expression of TGFB1 protein] CTD PMID:37148149 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO gossypin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; gossypin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; gossypin inhibits the reaction [Oleic Acid results in increased expression of TNF protein] CTD PMID:37148149 PMID:37696682 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
icariin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB1 adrenoceptor beta 1 increases expression ISO icariin results in increased expression of ADRB1 mRNA CTD PMID:16490167 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation		 ISO [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of AKT1 mRNA; [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of and results in decreased phosphorylation of AKT1 protein
icariin results in increased phosphorylation of AKT1 protein
afimoxifene inhibits the reaction [icariin results in increased phosphorylation of AKT1 protein]; icariin affects the reaction [Diethylhexyl Phthalate affects the phosphorylation of AKT1 protein]; icariin inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of AKT1 protein]; icariin inhibits the reaction [MK 2206 results in decreased phosphorylation of AKT1 protein]		 CTD PMID:32344236 PMID:35259346 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G APP amyloid beta precursor protein multiple interactions ISO icariin inhibits the reaction [APP protein alternative form results in decreased expression of SOD2 mRNA]; icariin inhibits the reaction [APP protein alternative form results in increased expression of BACE1 mRNA] CTD PMID:19782061 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G BACE1 beta-secretase 1 multiple interactions ISO icariin inhibits the reaction [APP protein alternative form results in increased expression of BACE1 mRNA] CTD PMID:19782061 NCBI chr11:117,285,698...117,316,256
Ensembl chr11:117,285,232...117,316,259 		JBrowse link
G BCL2 BCL2 apoptosis regulator affects expression
multiple interactions		 ISO
EXP		 icariin affects the expression of BCL2 protein
icariin inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in decreased expression of BCL2 protein]		 CTD PMID:25472572 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L11 BCL2 like 11 affects expression
multiple interactions		 ISO
EXP		 icariin affects the expression of BCL2L11 protein
icariin inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in increased expression of BCL2L11 protein]		 CTD PMID:25472572 NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,444 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein multiple interactions
increases expression		 ISO NOG protein inhibits the reaction [icariin results in increased expression of BGLAP mRNA]; SMAD6 protein inhibits the reaction [icariin results in increased expression of BGLAP mRNA] CTD PMID:18236786 PMID:18295595 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G BMP2 bone morphogenetic protein 2 multiple interactions
increases expression		 ISO
EXP		 NOG protein inhibits the reaction [icariin results in increased expression of BMP2 mRNA] CTD PMID:15724410 PMID:16543677 PMID:17355822 PMID:19747809 PMID:20019778 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246 		JBrowse link
G BMP4 bone morphogenetic protein 4 increases expression ISO icariin results in increased expression of BMP4 mRNA CTD PMID:18295595 PMID:20019778 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761 		JBrowse link
G CARTPT CART prepropeptide increases expression ISO icariin results in increased expression of CARTPT mRNA; icariin results in increased expression of CARTPT protein CTD PMID:19858766 NCBI chr 5:71,719,275...71,721,045
Ensembl chr 5:71,719,275...71,721,048 		JBrowse link
G CASP1 caspase 1 increases cleavage EXP icariin results in increased cleavage of CASP1 protein CTD PMID:35532261 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 increases phosphorylation
multiple interactions		 ISO icariin results in increased phosphorylation of CREB1 protein
[naphthol AS-E phosphate co-treated with icariin] results in increased phosphorylation of CREB1 protein; icariin inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of CREB1 protein]; icariin inhibits the reaction [MK 2206 results in decreased phosphorylation of CREB1 protein]		 CTD PMID:35259346 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 increases expression
multiple interactions		 ISO icariin results in increased expression of CYP11A1 mRNA; icariin results in increased expression of CYP11A1 protein
[icariin co-treated with Diethylhexyl Phthalate] results in increased expression of CYP11A1 mRNA; [icariin co-treated with naphthol AS-E phosphate] results in decreased expression of CYP11A1 protein; [MK 2206 co-treated with icariin] results in increased expression of CYP11A1 mRNA; icariin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of CYP11A1 protein]; icariin inhibits the reaction [MK 2206 results in decreased expression of CYP11A1 protein]		 CTD PMID:31175881 PMID:35259346 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646 		JBrowse link
G EGFR epidermal growth factor receptor multiple interactions ISO [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of and results in decreased phosphorylation of EGFR protein; [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of EGFR mRNA CTD PMID:32344236 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 ISO icariin results in increased expression of FOS mRNA; icariin results in increased expression of FOS protein
SB 203580 inhibits the reaction [icariin results in increased expression of FOS protein]; U 0126 inhibits the reaction [icariin results in increased expression of FOS protein]		 CTD PMID:18423597 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G FOXO3 forkhead box O3 multiple interactions
affects localization		 EXP
ISO		 icariin inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in increased acetylation of and results in increased expression of FOXO3 protein]; Niacinamide inhibits the reaction [icariin inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in increased acetylation of and results in increased expression of FOXO3 protein]]
icariin affects the localization of FOXO3 protein		 CTD PMID:25472572 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774 		JBrowse link
G GATA4 GATA binding protein 4 increases expression ISO icariin results in increased expression of GATA4 mRNA CTD PMID:16490167 NCBI chr 8:11,676,935...11,760,002
Ensembl chr 8:11,676,959...11,760,002 		JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 increases expression
multiple interactions		 ISO icariin results in increased expression of HSD3B1 mRNA; icariin results in increased expression of HSD3B1 protein
icariin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of HSD3B1 mRNA]; icariin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of HSD3B1 protein]		 CTD PMID:31175881 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054 		JBrowse link
G ID1 inhibitor of DNA binding 1 increases expression ISO icariin results in increased expression of ID1 mRNA CTD PMID:18295595 NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515 		JBrowse link
G IGF1 insulin like growth factor 1 increases expression ISO icariin results in increased expression of IGF1 mRNA CTD PMID:18236786 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IL1B interleukin 1 beta multiple interactions
increases expression		 ISO
EXP		 [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased secretion of IL1B protein
icariin results in increased expression of IL1B protein		 CTD PMID:32344236 PMID:35532261 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 affects expression
multiple interactions		 ISO icariin affects the expression of IL6 protein
[paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased secretion of IL6 protein		 CTD PMID:25472572 PMID:32344236 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 ISO icariin results in increased expression of JUN mRNA; icariin results in increased expression of JUN protein
SB 203580 inhibits the reaction [icariin results in increased expression of JUN protein]; U 0126 inhibits the reaction [icariin results in increased expression of JUN protein]		 CTD PMID:18423597 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation		 ISO U 0126 inhibits the reaction [icariin results in increased phosphorylation of MAPK1 protein] CTD PMID:18423597 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation		 ISO U 0126 inhibits the reaction [icariin results in increased phosphorylation of MAPK3 protein] CTD PMID:18423597 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MEF2C myocyte enhancer factor 2C affects localization
increases expression
multiple interactions		 ISO icariin affects the localization of MEF2C protein
icariin results in increased expression of MEF2C mRNA
SB 203580 inhibits the reaction [icariin affects the localization of MEF2C protein]; SB 203580 inhibits the reaction [icariin results in increased expression of MEF2C mRNA]; U 0126 inhibits the reaction [icariin affects the localization of MEF2C protein]; U 0126 inhibits the reaction [icariin results in increased expression of MEF2C mRNA]		 CTD PMID:18423597 NCBI chr 5:88,717,117...88,904,105
Ensembl chr 5:88,717,117...88,904,257 		JBrowse link
G MIR1224 microRNA 1224 decreases expression ISO icariin results in decreased expression of MIR1224 mRNA CTD PMID:30533443 NCBI chr 3:184,241,405...184,241,489
Ensembl chr 3:184,241,405...184,241,489 		JBrowse link
G MIR139 microRNA 139 decreases expression ISO icariin results in decreased expression of MIR139 mRNA CTD PMID:30533443 NCBI chr11:72,615,063...72,615,130
Ensembl chr11:72,615,063...72,615,130 		JBrowse link
G MIR140 microRNA 140 decreases expression ISO icariin results in decreased expression of MIR140 mRNA CTD PMID:30533443 NCBI chr16:69,933,081...69,933,180
Ensembl chr16:69,933,081...69,933,180 		JBrowse link
G MIR146B microRNA 146b increases expression ISO icariin results in increased expression of MIR146B mRNA CTD PMID:30533443 NCBI chr10:102,436,512...102,436,584
Ensembl chr10:102,436,512...102,436,584 		JBrowse link
G MIR150 microRNA 150 decreases expression ISO icariin results in decreased expression of MIR150 mRNA CTD PMID:30533443 NCBI chr19:49,500,785...49,500,868
Ensembl chr19:49,500,785...49,500,868 		JBrowse link
G MIR183 microRNA 183 increases expression ISO icariin results in increased expression of MIR183 mRNA CTD PMID:30533443 NCBI chr 7:129,774,905...129,775,014
Ensembl chr 7:129,774,905...129,775,014 		JBrowse link
G MIR199B microRNA 199b increases expression ISO icariin results in increased expression of MIR199B mRNA CTD PMID:30533443 NCBI chr 9:128,244,721...128,244,830
Ensembl chr 9:128,244,721...128,244,830 		JBrowse link
G MIR200A microRNA 200a increases expression ISO icariin results in increased expression of MIR200A mRNA CTD PMID:30533443 NCBI chr 1:1,167,863...1,167,952
Ensembl chr 1:1,167,863...1,167,952 		JBrowse link
G MIR200B microRNA 200b increases expression ISO icariin results in increased expression of MIR200B mRNA CTD PMID:30533443 NCBI chr 1:1,167,104...1,167,198
Ensembl chr 1:1,167,104...1,167,198 		JBrowse link
G MIR203B microRNA 203b increases expression ISO icariin results in increased expression of MIR203 mRNA CTD PMID:30533443 NCBI chr14:104,117,418...104,117,503
Ensembl chr14:104,117,418...104,117,503 		JBrowse link
G MIR205 microRNA 205 increases expression ISO icariin results in increased expression of MIR205 mRNA CTD PMID:30533443 NCBI chr 1:209,432,133...209,432,242
Ensembl chr 1:209,432,133...209,432,242 		JBrowse link
G MIR21 microRNA 21 increases expression ISO icariin results in increased expression of MIR21A mRNA CTD PMID:30533443 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MIR223 microRNA 223 decreases expression EXP icariin results in decreased expression of MIR223 mRNA CTD PMID:35532261 NCBI chr  X:66,018,870...66,018,979
Ensembl chr  X:66,018,870...66,018,979 		JBrowse link
G MIR2861 microRNA 2861 decreases expression ISO icariin results in decreased expression of MIR2861 mRNA CTD PMID:30533443 NCBI chr 9:127,785,918...127,786,007
Ensembl chr 9:127,785,918...127,786,007 		JBrowse link
G MIR30E microRNA 30e increases expression ISO icariin results in increased expression of MIR30E mRNA CTD PMID:30533443 NCBI chr 1:40,754,355...40,754,446
Ensembl chr 1:40,754,355...40,754,446 		JBrowse link
G MIR429 microRNA 429 increases expression ISO icariin results in increased expression of MIR429 mRNA CTD PMID:30533443 NCBI chr 1:1,169,005...1,169,087
Ensembl chr 1:1,169,005...1,169,087 		JBrowse link
G MIR455 microRNA 455 decreases expression ISO icariin results in decreased expression of MIR455 mRNA CTD PMID:30533443 NCBI chr 9:114,209,434...114,209,529
Ensembl chr 9:114,209,434...114,209,529 		JBrowse link
G MIR511 microRNA 511 increases expression ISO icariin results in increased expression of MIR511 mRNA CTD PMID:30533443 NCBI chr10:17,845,107...17,845,193
Ensembl chr10:17,845,107...17,845,193 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions ISO [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] affects the secretion of MMP9 protein CTD PMID:32344236 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions ISO [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of and results in decreased phosphorylation of MTOR protein; [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of MTOR mRNA CTD PMID:32344236 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of MUC5AC mRNA; [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased secretion of MUC5AC protein CTD PMID:32344236 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138 		JBrowse link
G MUC5B mucin 5B, oligomeric mucus/gel-forming multiple interactions ISO [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of MUC5B mRNA CTD PMID:32344236 NCBI chr11:1,223,066...1,262,172
Ensembl chr11:1,223,066...1,262,172 		JBrowse link
G MYH6 myosin heavy chain 6 increases expression ISO icariin results in increased expression of MYH6 mRNA CTD PMID:15780198 PMID:16490167 NCBI chr14:23,381,987...23,408,273
Ensembl chr14:23,381,982...23,408,273 		JBrowse link
G MYL2 myosin light chain 2 increases expression ISO icariin results in increased expression of MYL2 mRNA CTD PMID:15780198 PMID:16490167 NCBI chr12:110,910,845...110,921,449
Ensembl chr12:110,910,819...110,921,443 		JBrowse link
G NFE2L1 NFE2 like bZIP transcription factor 1 increases expression ISO icariin results in increased expression of NFE2L1 mRNA; icariin results in increased expression of NFE2L1 protein CTD PMID:17883938 NCBI chr17:48,048,359...48,061,545
Ensembl chr17:48,048,329...48,061,545 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO icariin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; icariin results in increased phosphorylation of and results in increased degradation of NFKBIA protein; SB 203580 inhibits the reaction [icariin results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; U 0126 inhibits the reaction [icariin results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:18423597 PMID:20686223 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NKX2-5 NK2 homeobox 5 increases expression ISO icariin results in increased expression of NKX2-5 mRNA CTD PMID:16490167 NCBI chr 5:173,232,109...173,235,206
Ensembl chr 5:173,232,109...173,235,311 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 increases expression EXP icariin results in increased expression of NLRP3 mRNA; icariin results in increased expression of NLRP3 protein CTD PMID:35532261 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108 		JBrowse link
G NOG noggin multiple interactions ISO NOG protein inhibits the reaction [icariin results in decreased expression of TNFSF11 mRNA]; NOG protein inhibits the reaction [icariin results in increased expression of BGLAP mRNA]; NOG protein inhibits the reaction [icariin results in increased expression of BMP2 mRNA]; NOG protein inhibits the reaction [icariin results in increased expression of RUNX2 mRNA]; NOG protein inhibits the reaction [icariin results in increased expression of SMAD4 mRNA]; NOG protein inhibits the reaction [icariin results in increased expression of SPP1 mRNA]; NOG protein inhibits the reaction [icariin results in increased expression of TNFRSF11B mRNA] CTD PMID:18295595 PMID:19747809 NCBI chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611 		JBrowse link
G NOS1 nitric oxide synthase 1 increases expression ISO icariin results in increased expression of NOS1 mRNA CTD PMID:16281085 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
increases expression		 ISO icariin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; icariin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
icariin results in increased expression of NOS2 mRNA; icariin results in increased expression of NOS2 protein		 CTD PMID:15329286 PMID:16281085 PMID:20686223 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 increases expression
multiple interactions		 EXP
ISO		 icariin results in increased expression of NOS3 mRNA
icariin results in increased expression of NOS3 mRNA; icariin results in increased expression of NOS3 protein
icariin promotes the reaction [NOS3 protein results in increased chemical synthesis of Nitric Oxide]; icariin results in increased expression of and results in increased activity of NOS3 protein		 CTD PMID:15329286 PMID:17499557 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NR5A1 nuclear receptor subfamily 5 group A member 1 multiple interactions
increases expression		 ISO icariin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of NR5A1 mRNA]; icariin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of NR5A1 protein]
icariin results in increased expression of NR5A1 mRNA; icariin results in increased expression of NR5A1 protein		 CTD PMID:31175881 PMID:35259346 NCBI chr 9:124,481,236...124,507,399
Ensembl chr 9:124,481,236...124,507,420 		JBrowse link
G PDE5A phosphodiesterase 5A decreases activity
decreases expression		 EXP
ISO		 icariin analog results in decreased activity of PDE5A protein; icariin results in decreased activity of PDE5A protein
icariin results in decreased expression of PDE5A mRNA alternative form		 CTD PMID:17120748 PMID:18778098 NCBI chr 4:119,494,403...119,628,804
Ensembl chr 4:119,494,397...119,628,804 		JBrowse link
G PGR progesterone receptor increases expression
multiple interactions		 EXP icariin results in increased expression of PGR mRNA
fulvestrant inhibits the reaction [icariin results in increased expression of PGR mRNA]		 CTD PMID:15541416 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha increases expression ISO icariin results in increased expression of PPARA mRNA; icariin results in increased expression of PPARA protein CTD PMID:17883938 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha increases expression
multiple interactions		 ISO icariin results in increased expression of PPARGC1A mRNA; icariin results in increased expression of PPARGC1A protein
Histone Deacetylase Inhibitors inhibits the reaction [icariin inhibits the reaction [Rotenone results in decreased expression of PPARGC1A protein]]; icariin inhibits the reaction [Rotenone results in decreased expression of PPARGC1A protein]		 CTD PMID:17883938 PMID:31251943 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO icariin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; icariin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:20686223 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit increases activity
multiple interactions		 EXP
ISO		 icariin results in increased activity of RELA protein
icariin inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]; icariin results in increased expression of and affects the localization of RELA protein; SB 203580 inhibits the reaction [icariin results in increased expression of and affects the localization of RELA protein]; U 0126 inhibits the reaction [icariin results in increased expression of and affects the localization of RELA protein]		 CTD PMID:17499557 PMID:18423597 PMID:20686223 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RUNX2 RUNX family transcription factor 2 increases expression
multiple interactions		 ISO icariin results in increased expression of RUNX2 mRNA
NOG protein inhibits the reaction [icariin results in increased expression of RUNX2 mRNA]		 CTD PMID:18295595 PMID:19747809 PMID:20019778 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349 		JBrowse link
G SIRT1 sirtuin 1 multiple interactions
affects expression
increases expression		 ISO
EXP		 icariin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of SIRT1 mRNA]; icariin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of SIRT1 protein]; SB 203580 inhibits the reaction [icariin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of SIRT1 mRNA]]; SB 203580 inhibits the reaction [icariin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of SIRT1 protein]]
icariin affects the expression of SIRT1 mRNA; icariin affects the expression of SIRT1 protein
icariin inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in decreased expression of SIRT1 protein]; Niacinamide inhibits the reaction [icariin inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in decreased expression of SIRT1 protein]]
icariin results in increased expression of SIRT1 mRNA; icariin results in increased expression of SIRT1 protein		 CTD PMID:19303870 PMID:25472572 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SIRT3 sirtuin 3 multiple interactions ISO Histone Deacetylase Inhibitors inhibits the reaction [icariin inhibits the reaction [Rotenone results in decreased expression of SIRT3 protein]]; icariin inhibits the reaction [Rotenone results in decreased expression of SIRT3 protein] CTD PMID:31251943 NCBI chr11:215,030...236,931
Ensembl chr11:215,030...236,931 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 multiple interactions
decreases activity		 EXP [icariin results in decreased activity of SLCO1B3 protein] which results in decreased uptake of Sincalide CTD PMID:24265111 NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911 		JBrowse link
G SLCO2B1 solute carrier organic anion transporter family member 2B1 multiple interactions
decreases activity		 EXP [icariin results in decreased activity of SLCO2B1 protein] which results in decreased uptake of estrone sulfate CTD PMID:24265111 NCBI chr11:75,151,107...75,206,549
Ensembl chr11:75,100,563...75,206,549 		JBrowse link
G SMAD4 SMAD family member 4 increases expression
multiple interactions		 ISO icariin results in increased expression of SMAD4 mRNA
NOG protein inhibits the reaction [icariin results in increased expression of SMAD4 mRNA]		 CTD PMID:19747809 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045 		JBrowse link
G SMAD6 SMAD family member 6 multiple interactions ISO SMAD6 protein inhibits the reaction [icariin results in increased expression of BGLAP mRNA]; SMAD6 protein inhibits the reaction [icariin results in increased expression of SPP1 mRNA] CTD PMID:18295595 NCBI chr15:66,702,236...66,782,849
Ensembl chr15:66,702,236...66,782,849 		JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions
affects expression		 ISO
EXP		 icariin inhibits the reaction [APP protein alternative form results in decreased expression of SOD2 mRNA]
icariin inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in decreased expression of SOD2 protein]
icariin affects the expression of SOD2 protein		 CTD PMID:19782061 PMID:25472572 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SPP1 secreted phosphoprotein 1 multiple interactions
increases expression		 ISO NOG protein inhibits the reaction [icariin results in increased expression of SPP1 mRNA]; SMAD6 protein inhibits the reaction [icariin results in increased expression of SPP1 mRNA] CTD PMID:16696327 PMID:18236786 PMID:18295595 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase increases phosphorylation
multiple interactions		 ISO icariin results in increased phosphorylation of SRC protein
afimoxifene inhibits the reaction [icariin results in increased phosphorylation of SRC protein]; icariin inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of SRC protein]		 CTD PMID:35259346 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G TFF1 trefoil factor 1 multiple interactions
increases expression		 EXP fulvestrant inhibits the reaction [icariin results in increased expression of TFF1 mRNA] CTD PMID:15541416 NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535 		JBrowse link
G TGFB1 transforming growth factor beta 1 increases expression ISO icariin results in increased expression of TGFB1 mRNA CTD PMID:18236786 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TH tyrosine hydroxylase multiple interactions ISO icariin inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:31251943 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] affects the secretion of TIMP1 protein CTD PMID:32344236 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TNF tumor necrosis factor multiple interactions
affects expression		 ISO icariin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; icariin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
[paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased secretion of TNF protein
icariin affects the expression of TNF protein		 CTD PMID:20686223 PMID:25472572 PMID:32344236 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b increases expression
multiple interactions		 ISO icariin results in increased expression of TNFRSF11B mRNA
NOG protein inhibits the reaction [icariin results in increased expression of TNFRSF11B mRNA]		 CTD PMID:19747809 NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885 		JBrowse link
G TNFSF11 TNF superfamily member 11 decreases expression
multiple interactions		 ISO icariin results in decreased expression of TNFSF11 mRNA
NOG protein inhibits the reaction [icariin results in decreased expression of TNFSF11 mRNA]		 CTD PMID:19747809 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013 		JBrowse link
G TP53 tumor protein p53 increases expression ISO icariin results in increased expression of TRP53 mRNA; icariin results in increased expression of TRP53 protein CTD PMID:15878162 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
icariside II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB11 ATP binding cassette subfamily B member 11 decreases expression ISO
EXP		 baohuoside I results in decreased expression of ABCB11 mRNA; baohuoside I results in decreased expression of ABCB11 protein CTD PMID:35802278 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 decreases expression ISO
EXP		 baohuoside I results in decreased expression of ABCC2 mRNA; baohuoside I results in decreased expression of ABCC2 protein CTD PMID:35802278 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions		 EXP baohuoside I results in decreased phosphorylation of AKT1 protein
baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]		 CTD PMID:25119583 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G AKT1S1 AKT1 substrate 1 multiple interactions
decreases phosphorylation		 EXP baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein]
baohuoside I results in decreased phosphorylation of AKT1S1 protein		 CTD PMID:25119583 NCBI chr19:49,869,033...49,878,356
Ensembl chr19:49,869,033...49,878,459 		JBrowse link
G ALPL alkaline phosphatase, biomineralization associated increases expression
increases secretion		 ISO baohuoside I results in increased expression of ALPL mRNA
baohuoside I results in increased secretion of ALPL protein		 CTD PMID:17764702 PMID:35802278 NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression EXP baohuoside I results in increased expression of BAX protein CTD PMID:22687635 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP baohuoside I results in decreased expression of BCL2 protein CTD PMID:22687635 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein increases expression ISO baohuoside I results in increased expression of BGLAP mRNA CTD PMID:17764702 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase decreases phosphorylation
multiple interactions		 EXP baohuoside I results in decreased phosphorylation of BRAF protein
baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of BRAF protein]		 CTD PMID:25119583 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929 		JBrowse link
G CASP3 caspase 3 increases cleavage
increases activity		 EXP baohuoside I results in increased cleavage of CASP3 protein
baohuoside I results in increased activity of CASP3 protein		 CTD PMID:19289254 PMID:22687635 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP8 caspase 8 increases activity EXP baohuoside I results in increased activity of CASP8 protein CTD PMID:19289254 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 increases activity
increases cleavage		 EXP baohuoside I results in increased activity of CASP9 protein
baohuoside I results in increased cleavage of CASP9 protein		 CTD PMID:19289254 PMID:22687635 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G COL1A2 collagen type I alpha 2 chain increases expression ISO baohuoside I results in increased expression of COL1A2 mRNA CTD PMID:17764702 NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 increases expression ISO
EXP		 baohuoside I results in increased expression of CYP7A1 mRNA; baohuoside I results in increased expression of CYP7A1 protein CTD PMID:35802278 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163 		JBrowse link
G EGF epidermal growth factor multiple interactions EXP baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of BRAF protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MTOR protein] CTD PMID:25119583 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGFR epidermal growth factor receptor multiple interactions
decreases phosphorylation		 EXP baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]
baohuoside I results in decreased phosphorylation of EGFR protein		 CTD PMID:25119583 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G ESR1 estrogen receptor 1 multiple interactions EXP baohuoside I binds to and results in increased degradation of ESR1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [baohuoside I results in increased degradation of ESR1 protein]; ESR1 inhibits the reaction [baohuoside I results in decreased expression of and affects the localization of NR0B2 protein] CTD PMID:35802278 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 increases secretion ISO
EXP		 baohuoside I results in increased secretion of GOT1 protein CTD PMID:35802278 NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624 		JBrowse link
G GPT glutamic--pyruvic transaminase increases secretion ISO
EXP		 baohuoside I results in increased secretion of GPT protein CTD PMID:35802278 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta decreases phosphorylation EXP baohuoside I results in decreased phosphorylation of GSK3B protein CTD PMID:25119583 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
decreases phosphorylation		 EXP baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]
baohuoside I results in decreased phosphorylation of MAPK1 protein		 CTD PMID:25119583 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
decreases phosphorylation		 EXP baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]
baohuoside I results in decreased phosphorylation of MAPK3 protein		 CTD PMID:25119583 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MKI67 marker of proliferation Ki-67 decreases expression EXP baohuoside I results in decreased expression of MKI67 protein CTD PMID:25119583 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions
decreases phosphorylation		 EXP baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MTOR protein]
baohuoside I results in decreased phosphorylation of MTOR protein		 CTD PMID:25119583 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G NOS2 nitric oxide synthase 2 decreases expression EXP baohuoside I results in decreased expression of NOS2 CTD PMID:19289254 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 decreases expression
multiple interactions		 ISO
EXP		 baohuoside I results in decreased expression of NR0B2 mRNA; baohuoside I results in decreased expression of NR0B2 protein
baohuoside I results in decreased expression of and results in decreased activity of and affects the localization of NR0B2 protein; ESR1 inhibits the reaction [baohuoside I results in decreased expression of and affects the localization of NR0B2 protein]		 CTD PMID:35802278 NCBI chr 1:26,911,489...26,913,975
Ensembl chr 1:26,911,489...26,913,975 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 decreases expression EXP
ISO		 baohuoside I results in decreased expression of NR1H4 mRNA; baohuoside I results in decreased expression of NR1H4 protein CTD PMID:35802278 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 increases cleavage
multiple interactions		 EXP baohuoside I results in increased cleavage of PARP1 protein
Dinoprostone inhibits the reaction [baohuoside I results in increased cleavage of PARP1 protein]; PTGS2 mutant form promotes the reaction [baohuoside I results in increased cleavage of PARP1 protein]		 CTD PMID:19289254 PMID:22687635 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 decreases phosphorylation EXP baohuoside I results in decreased phosphorylation of PDPK1 protein CTD PMID:25119583 NCBI chr16:2,538,021...2,603,188
Ensembl chr16:2,537,979...2,603,188 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions		 EXP baohuoside I results in decreased expression of PTGS2
[baohuoside I results in decreased expression of PTGS2] which results in decreased abundance of Dinoprostone; PTGS2 mutant form promotes the reaction [baohuoside I results in increased cleavage of PARP1 protein]		 CTD PMID:19289254 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G SLC10A1 solute carrier family 10 member 1 increases expression ISO
EXP		 baohuoside I results in increased expression of SLC10A1 mRNA; baohuoside I results in increased expression of SLC10A1 protein CTD PMID:35802278 NCBI chr14:69,775,416...69,797,241
Ensembl chr14:69,775,416...69,797,241 		JBrowse link
G SLCO1A2 solute carrier organic anion transporter family member 1A2 decreases expression EXP baohuoside I results in decreased expression of SLCO1A1 mRNA CTD PMID:35802278 NCBI chr12:21,264,600...21,419,634
Ensembl chr12:21,264,600...21,419,594 		JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b increases expression ISO baohuoside I results in increased expression of TNFRSF11B mRNA CTD PMID:17764702 NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885 		JBrowse link
G TNFSF11 TNF superfamily member 11 decreases expression ISO baohuoside I results in decreased expression of TNFSF11 mRNA CTD PMID:17764702 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013 		JBrowse link
G VEGFA vascular endothelial growth factor A decreases expression EXP baohuoside I results in decreased expression of VEGFA CTD PMID:19289254 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
kaempferol 3-O-beta-D-galactoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLA2G2A phospholipase A2 group IIA affects activity EXP kaempferol-3-O-galactoside affects the activity of PLA2G2A protein CTD PMID:8190018 NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416 		JBrowse link
kaempferol 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of APP protein] CTD PMID:35537655 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G CAT catalase multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of CAT protein] CTD PMID:35537655 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions ISO astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA] CTD PMID:22210036 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 multiple interactions ISO astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL3 mRNA] CTD PMID:22210036 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G HES1 hes family bHLH transcription factor 1 multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of HES1 protein] CTD PMID:35537655 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732 		JBrowse link
G IL10 interleukin 10 multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of IL10 protein] CTD PMID:35537655 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of IL1B protein]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:22210036 PMID:35537655 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of IL6 protein]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:22210036 PMID:35537655 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO astragalin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:22210036 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:22210036 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOTCH1 notch receptor 1 multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of NOTCH1 protein] CTD PMID:35537655 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:22210036 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of RBPJ protein] CTD PMID:35537655 NCBI chr 4:26,105,449...26,435,131
Ensembl chr 4:26,163,455...26,435,131 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of and results in increased phosphorylation of RELA protein]; astragalin inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] CTD PMID:22210036 PMID:35537655 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of TNF protein]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] CTD PMID:22210036 PMID:35537655 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
luteolin 7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation		 EXP [luteolin-7-glucoside co-treated with Hydrogen Peroxide] results in increased phosphorylation of AKT1 protein
luteolin-7-glucoside results in decreased phosphorylation of AKT1 protein		 CTD PMID:31157476 PMID:34165247 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression EXP luteolin-7-glucoside results in increased expression of BAX protein CTD PMID:34165247 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression		 EXP luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]; luteolin-7-glucoside inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]
luteolin-7-glucoside results in decreased expression of BCL2 protein		 CTD PMID:31157476 PMID:31381935 PMID:34165247 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 decreases expression EXP luteolin-7-glucoside results in decreased expression of BCL2L1 protein CTD PMID:34165247 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BID BH3 interacting domain death agonist increases expression EXP luteolin-7-glucoside results in increased expression of BID protein alternative form CTD PMID:34165247 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G CASP3 caspase 3 multiple interactions
increases cleavage		 EXP benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [luteolin-7-glucoside results in increased cleavage of CASP3 protein]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP3 protein modified form]; luteolin-7-glucoside inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP3 protein] CTD PMID:31157476 PMID:31381935 PMID:34165247 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP8 caspase 8 increases cleavage EXP luteolin-7-glucoside results in increased cleavage of CASP8 protein CTD PMID:34165247 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 increases cleavage EXP luteolin-7-glucoside results in increased cleavage of CASP9 protein CTD PMID:34165247 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase multiple interactions EXP luteolin-7-glucoside inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein] CTD PMID:31157476 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCNA2 cyclin A2 decreases expression EXP luteolin-7-glucoside results in decreased expression of CCNA2 protein CTD PMID:34165247 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883 		JBrowse link
G CCNB1 cyclin B1 decreases expression EXP luteolin-7-glucoside results in decreased expression of CCNB1 protein CTD PMID:34165247 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245 		JBrowse link
G CDK1 cyclin dependent kinase 1 decreases phosphorylation EXP luteolin-7-glucoside results in decreased phosphorylation of CDK1 protein CTD PMID:34165247 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852 		JBrowse link
G CDK2 cyclin dependent kinase 2 decreases expression EXP luteolin-7-glucoside results in decreased expression of CDK2 protein CTD PMID:34165247 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression EXP luteolin-7-glucoside results in increased expression of CDKN1A protein CTD PMID:34165247 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G ESR1 estrogen receptor 1 multiple interactions
increases activity		 EXP 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR1 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR1 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR1 protein]
luteolin-7-glucoside results in increased activity of ESR1 protein		 CTD PMID:31381935 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G ESR2 estrogen receptor 2 increases activity
multiple interactions		 EXP luteolin-7-glucoside results in increased activity of ESR2 protein
4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR2 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR2 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR2 protein]		 CTD PMID:31381935 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G FAS Fas cell surface death receptor increases expression EXP luteolin-7-glucoside results in increased expression of FAS protein CTD PMID:34165247 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of FOS protein]]; 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of FOS protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of FOS protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of FOS protein] CTD PMID:31381935 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO luteolin-7-glucoside inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 protein] CTD PMID:11123379 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 decreases phosphorylation
multiple interactions		 EXP luteolin-7-glucoside results in decreased phosphorylation of MAPK1 protein
1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]]; 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]		 CTD PMID:31381935 PMID:34165247 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
decreases phosphorylation		 EXP 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]]; 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]
luteolin-7-glucoside results in decreased phosphorylation of MAPK3 protein		 CTD PMID:31381935 PMID:34165247 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions
increases cleavage		 EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein]; pyrazolanthrone inhibits the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein]; SB 203580 promotes the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein]; U 0126 inhibits the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein] CTD PMID:34165247 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 increases expression EXP luteolin-7-glucoside results in increased expression of RIPK1 protein CTD PMID:34165247 NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 multiple interactions EXP 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of STAT3 protein]]; 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of STAT3 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of STAT3 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of STAT3 protein] CTD PMID:31381935 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO luteolin-7-glucoside inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF protein] CTD PMID:11123379 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF10B TNF receptor superfamily member 10b increases expression EXP luteolin-7-glucoside results in increased expression of TNFRSF10B protein CTD PMID:34165247 NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A increases expression EXP luteolin-7-glucoside results in increased expression of TNFRSF1A protein CTD PMID:34165247 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
miquelianin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACADM acyl-CoA dehydrogenase medium chain multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA] CTD PMID:26190035 NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,431...75,787,575 		JBrowse link
G ADRB2 adrenoceptor beta 2 multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine binds to ADRB2 protein] CTD PMID:24929186 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623 		JBrowse link
G AGT angiotensinogen multiple interactions EXP quercetin 3-O-glucuronide analog inhibits the reaction [AGT protein results in increased phosphorylation of JUN protein] CTD PMID:12054679 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [ALOX5 protein results in increased chemical synthesis of Leukotriene B4] CTD PMID:18096136 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G APP amyloid beta precursor protein multiple interactions
decreases expression		 EXP quercetin 3-O-glucuronide inhibits the reaction [APP protein binds to APP protein modified form]
quercetin 3-O-glucuronide results in decreased expression of APP protein		 CTD PMID:23097297 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G CAT catalase multiple interactions ISO [quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of CAT mRNA; [quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of CAT protein CTD PMID:25716194 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CAV1 caveolin 1 multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [Lysophosphatidylcholines results in increased expression of CAV1 mRNA] CTD PMID:27257344 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) decreases expression ISO quercetin 3-O-glucuronide results in decreased expression of CD36 mRNA CTD PMID:18199750 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA] CTD PMID:26190035 NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410 		JBrowse link
G FAS Fas cell surface death receptor multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS mRNA]; quercetin 3-O-glucuronide inhibits the reaction [Dietary Fats results in increased expression of FAS mRNA] CTD PMID:26190035 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit multiple interactions ISO [quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of GCLC mRNA; [quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of GCLC protein CTD PMID:25716194 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions EXP
ISO		 quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine results in increased expression of HMOX1 mRNA]
[quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of HMOX1 mRNA; [quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of HMOX1 protein		 CTD PMID:24929186 PMID:25716194 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [Lysophosphatidylcholines results in increased expression of ICAM1 mRNA] CTD PMID:27257344 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [Palmitates results in increased phosphorylation of IKBKB protein] CTD PMID:23504962 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein] CTD PMID:26190035 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [Palmitates results in increased secretion of IL6 protein] CTD PMID:23504962 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INS insulin multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [Palmitates inhibits the reaction [INS protein results in increased chemical synthesis of Nitric Oxide]]; quercetin 3-O-glucuronide inhibits the reaction [Palmitates inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]]; quercetin 3-O-glucuronide inhibits the reaction [Palmitates inhibits the reaction [INS protein results in increased phosphorylation of NOS3 protein]] CTD PMID:23504962 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G IRS1 insulin receptor substrate 1 multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [Palmitates inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]]; quercetin 3-O-glucuronide inhibits the reaction [Palmitates results in increased phosphorylation of IRS1 protein] CTD PMID:23504962 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP quercetin 3-O-glucuronide analog inhibits the reaction [AGT protein results in increased phosphorylation of JUN protein] CTD PMID:12054679 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine results in increased expression of MMP2 mRNA] CTD PMID:24929186 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine results in increased activity of MMP9 protein]; quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine results in increased expression of MMP9 mRNA] CTD PMID:24929186 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MSR1 macrophage scavenger receptor 1 decreases expression ISO quercetin 3-O-glucuronide results in decreased expression of MSR1 mRNA CTD PMID:18199750 NCBI chr 8:16,107,881...16,192,651
Ensembl chr 8:16,107,878...16,567,490 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein] CTD PMID:27257013 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [Palmitates inhibits the reaction [INS protein results in increased phosphorylation of NOS3 protein]] CTD PMID:23504962 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein]; quercetin 3-O-glucuronide inhibits the reaction [Dietary Fats results in decreased expression of PPARA protein] CTD PMID:26190035 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma increases expression EXP quercetin 3-O-glucuronide results in increased expression of PPARG mRNA CTD PMID:25765892 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein] CTD PMID:27257013 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [Palmitates results in increased phosphorylation of RELA protein] CTD PMID:23504962 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G SLC22A8 solute carrier family 22 member 8 multiple interactions
increases uptake		 EXP quercetin 3-O-glucuronide analog inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein]; quercetin 3-O-glucuronide inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein]
SLC22A8 protein results in increased uptake of quercetin 3-O-glucuronide analog		 CTD PMID:21244849 NCBI chr11:62,992,824...63,015,841
Ensembl chr11:62,989,154...63,015,841 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA]; quercetin 3-O-glucuronide inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:26190035 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G TNF tumor necrosis factor multiple interactions EXP
ISO		 quercetin 3-O-glucuronide inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with TNF protein] results in increased expression of VCAM1 protein]; quercetin 3-O-glucuronide inhibits the reaction [Palmitates results in increased secretion of TNF protein]
quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]		 CTD PMID:17880982 PMID:23504962 PMID:26190035 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFSF11 TNF superfamily member 11 decreases activity ISO quercetin 3-O-glucuronide results in decreased activity of TNFSF11 protein CTD PMID:19495926 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with TNF protein] results in increased expression of VCAM1 protein] CTD PMID:17880982 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
myricitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTA2 actin alpha 2, smooth muscle multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:25656916 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,935,074...88,991,339 		JBrowse link
G ALPL alkaline phosphatase, biomineralization associated multiple interactions ISO
EXP		 myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ALPL mRNA] CTD PMID:25130202 NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410 		JBrowse link
G APOE apolipoprotein E multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in decreased activity of CAT protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased activity of CASP3 protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CCL2 protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CRP protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of ICAM1 protein] CTD PMID:23639522 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein] CTD PMID:23639522 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions EXP myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:23639522 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein multiple interactions ISO
EXP		 myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BGLAP mRNA] CTD PMID:25130202 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G CASP3 caspase 3 multiple interactions EXP
ISO		 myricitrin inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]
myricitrin inhibits the reaction [APOE gene mutant form results in increased activity of CASP3 protein]		 CTD PMID:23639522 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CAT catalase multiple interactions EXP
ISO		 myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein]
myricitrin inhibits the reaction [APOE gene mutant form results in decreased activity of CAT protein]		 CTD PMID:23639522 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CCL2 protein] CTD PMID:23639522 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions ISO
EXP		 myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of COL1A1 mRNA] CTD PMID:25130202 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G CRP C-reactive protein multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CRP protein] CTD PMID:23639522 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein] CTD PMID:25656916 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein] CTD PMID:25656916 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions EXP myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of GPX1 protein] CTD PMID:23639522 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of ICAM1 protein] CTD PMID:23639522 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IL6 interleukin 6 multiple interactions EXP
ISO		 myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of IL6 protein] CTD PMID:25130202 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] CTD PMID:23639522 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein] CTD PMID:23639522 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions EXP myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:23639522 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions EXP myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of NOS3 protein] CTD PMID:23639522 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions ISO myricitrin promotes the reaction [Carbon Tetrachloride results in increased expression of PCNA protein] CTD PMID:25656916 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions EXP myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of PPARG mRNA] CTD PMID:25130202 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein] CTD PMID:25656916 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein] CTD PMID:25656916 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein] CTD PMID:25656916 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFSF11 TNF superfamily member 11 multiple interactions ISO
EXP		 myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFSF11 protein] CTD PMID:25130202 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013 		JBrowse link
G TP53 tumor protein p53 multiple interactions EXP myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein] CTD PMID:23639522 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
quercetin 3-O-beta-D-galactopyranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Yt blood group) increases expression
multiple interactions		 ISO hyperoside results in increased expression of ACHE mRNA
hyperoside results in increased expression of and results in increased activity of ACHE protein		 CTD PMID:27019979 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP
ISO		 hyperoside inhibits the reaction [tert-Butylhydroperoxide affects the localization of BAX protein]
hyperoside inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein]		 CTD PMID:18552516 PMID:31326407 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions ISO hyperoside inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:31326407 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 multiple interactions EXP [Quercetin co-treated with hyperoside] results in decreased expression of BIRC5 mRNA; [Quercetin co-treated with hyperoside] results in decreased expression of BIRC5 protein CTD PMID:24173369 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G CASP3 caspase 3 multiple interactions EXP [Quercetin co-treated with hyperoside] results in increased cleavage of CASP3 protein CTD PMID:24173369 PMID:25354548 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CAT catalase multiple interactions ISO cyclopamine inhibits the reaction [hyperoside inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein]]; hyperoside inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein] CTD PMID:31326407 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CYCS cytochrome c, somatic multiple interactions EXP hyperoside inhibits the reaction [tert-Butylhydroperoxide affects the localization of CYCS protein] CTD PMID:18552516 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 decreases activity
multiple interactions		 ISO hyperoside results in decreased activity of CYP2E1 protein
hyperoside inhibits the reaction [Acetaminophen results in decreased activity of CYP2E1 protein]		 CTD PMID:26772156 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G ESR1 estrogen receptor 1 multiple interactions EXP hyperoside inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:22613215 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G GLI1 GLI family zinc finger 1 multiple interactions
increases expression		 ISO hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of GLI1 mRNA]; hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of GLI1 protein]
hyperoside results in increased expression of GLI1 mRNA; hyperoside results in increased expression of GLI1 protein		 CTD PMID:31326407 NCBI chr12:57,459,785...57,472,268
Ensembl chr12:57,459,785...57,472,268 		JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO hyperoside inhibits the reaction [Acetaminophen results in increased activity of GPT protein] CTD PMID:26772156 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein] CTD PMID:30125551 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:30125551 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MIR21 microRNA 21 multiple interactions EXP [Quercetin co-treated with hyperoside] results in decreased expression of MIR21 mRNA; MIR21 mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of PDCD4 mRNA]; MIR21 mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of PDCD4 protein]; MIR21 mRNA results in decreased susceptibility to [Quercetin co-treated with hyperoside] CTD PMID:25354548 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MIR27A microRNA 27a multiple interactions EXP [Quercetin co-treated with hyperoside] inhibits the reaction [MIR27A mRNA results in decreased expression of ZBTB10 mRNA]; [Quercetin co-treated with hyperoside] inhibits the reaction [MIR27A mRNA results in increased expression of SP1 mRNA]; [Quercetin co-treated with hyperoside] results in decreased expression of MIR27A mRNA; MIR27A mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of ZBTB10 mRNA] CTD PMID:24173369 NCBI chr19:13,836,440...13,836,517
Ensembl chr19:13,836,440...13,836,517 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 affects localization ISO hyperoside affects the localization of NFE2L2 protein CTD PMID:26772156 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:30125551 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Hyperoside increases expression of Nqo1 protein in liver RGD PMID:31399183 RGD:25823190 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions EXP [Quercetin co-treated with hyperoside] results in increased cleavage of PARP1 protein CTD PMID:24173369 PMID:25354548 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PDCD4 programmed cell death 4 multiple interactions EXP [Quercetin co-treated with hyperoside] results in increased expression of PDCD4 mRNA; [Quercetin co-treated with hyperoside] results in increased expression of PDCD4 protein; MIR21 mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of PDCD4 mRNA]; MIR21 mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of PDCD4 protein] CTD PMID:25354548 NCBI chr10:110,871,928...110,900,006
Ensembl chr10:110,871,795...110,900,006 		JBrowse link
G PRIMA1 proline rich membrane anchor 1 increases expression ISO hyperoside results in increased expression of PRIMA1 mRNA CTD PMID:27019979 NCBI chr14:93,718,298...93,788,994
Ensembl chr14:93,718,298...93,788,485 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein] CTD PMID:30125551 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G SHH sonic hedgehog signaling molecule multiple interactions
increases expression		 ISO hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of SHH mRNA]; hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of SHH protein]
hyperoside results in increased expression of SHH mRNA; hyperoside results in increased expression of SHH protein		 CTD PMID:31326407 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463 		JBrowse link
G SIRT1 sirtuin 1 multiple interactions EXP hyperoside inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of SIRT1 protein] CTD PMID:18552516 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SLC2A2 solute carrier family 2 member 2 increases expression EXP hyperoside analog results in increased expression of SLC2A2 mRNA CTD PMID:33493636 NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743 		JBrowse link
G SLC5A1 solute carrier family 5 member 1 increases expression EXP hyperoside analog results in increased expression of SLC5A1 mRNA CTD PMID:33493636 NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029 		JBrowse link
G SMO smoothened, frizzled class receptor multiple interactions
increases expression		 ISO hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of SMO mRNA]; hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of SMO protein]
hyperoside results in increased expression of SMO mRNA; hyperoside results in increased expression of SMO protein		 CTD PMID:31326407 NCBI chr 7:129,188,633...129,213,545
Ensembl chr 7:129,188,633...129,213,545 		JBrowse link
G SP1 Sp1 transcription factor multiple interactions EXP [Quercetin co-treated with hyperoside] inhibits the reaction [MIR27A mRNA results in increased expression of SP1 mRNA]; [Quercetin co-treated with hyperoside] results in decreased expression of SP1 mRNA; [Quercetin co-treated with hyperoside] results in decreased expression of SP1 protein CTD PMID:24173369 NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446 		JBrowse link
G SP3 Sp3 transcription factor multiple interactions EXP [Quercetin co-treated with hyperoside] results in decreased expression of SP3 mRNA; [Quercetin co-treated with hyperoside] results in decreased expression of SP3 protein CTD PMID:24173369 NCBI chr 2:173,900,775...173,965,702
Ensembl chr 2:173,880,850...173,965,373 		JBrowse link
G SP4 Sp4 transcription factor multiple interactions EXP [Quercetin co-treated with hyperoside] results in decreased expression of SP4 mRNA; [Quercetin co-treated with hyperoside] results in decreased expression of SP4 protein CTD PMID:24173369 NCBI chr 7:21,428,083...21,514,822
Ensembl chr 7:21,428,043...21,514,822 		JBrowse link
G SULT1A2 sulfotransferase family 1A member 2 multiple interactions ISO hyperoside inhibits the reaction [Acetaminophen results in decreased expression of SULT1A1 mRNA] CTD PMID:26772156 NCBI chr16:28,591,943...28,597,050
Ensembl chr16:28,591,943...28,597,050 		JBrowse link
G SULT2A1 sulfotransferase family 2A member 1 multiple interactions
increases expression		 ISO hyperoside inhibits the reaction [Acetaminophen results in decreased expression of SULT2A1 mRNA]
hyperoside results in increased expression of SULT2A1 mRNA		 CTD PMID:26772156 NCBI chr19:47,870,467...47,886,315
Ensembl chr19:47,870,467...47,886,315 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased expression of TNFRSF1A protein]; hyperoside inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; hyperoside inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein] CTD PMID:30125551 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased expression of TNFRSF1A protein] CTD PMID:30125551 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 multiple interactions
increases expression		 ISO hyperoside inhibits the reaction [Acetaminophen results in decreased expression of UGT1A1 mRNA]
hyperoside results in increased expression of UGT1A1 mRNA		 CTD PMID:26772156 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300 		JBrowse link
G UGT1A10 UDP glucuronosyltransferase family 1 member A10 increases expression
multiple interactions		 ISO hyperoside results in increased expression of UGT1A10 mRNA
hyperoside inhibits the reaction [Acetaminophen results in decreased expression of UGT1A10 mRNA]		 CTD PMID:26772156 NCBI chr 2:233,636,448...233,773,300
Ensembl chr 2:233,636,448...233,773,300 		JBrowse link
G UGT1A6 UDP glucuronosyltransferase family 1 member A6 multiple interactions ISO hyperoside inhibits the reaction [Acetaminophen results in decreased expression of UGT1A6 mRNA] CTD PMID:26772156 NCBI chr 2:233,691,702...233,773,300
Ensembl chr 2:233,691,607...233,773,300 		JBrowse link
G UGT2B17 UDP glucuronosyltransferase family 2 member B17 multiple interactions
increases expression		 ISO hyperoside inhibits the reaction [Acetaminophen results in decreased expression of UGT2B1 mRNA]
hyperoside results in increased expression of UGT2B1 mRNA		 CTD PMID:26772156 NCBI chr 4:68,537,173...68,576,322
Ensembl chr 4:68,537,173...68,576,413 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; hyperoside inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:30125551 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
G ZBTB10 zinc finger and BTB domain containing 10 multiple interactions EXP [Quercetin co-treated with hyperoside] inhibits the reaction [MIR27A mRNA results in decreased expression of ZBTB10 mRNA]; [Quercetin co-treated with hyperoside] results in increased expression of ZBTB10 mRNA; MIR27A mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of ZBTB10 mRNA] CTD PMID:24173369 NCBI chr 8:80,485,593...80,526,265
Ensembl chr 8:80,485,619...80,526,265 		JBrowse link
quercetin 3-O-beta-D-glucofuranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT2 acetyl-CoA acetyltransferase 2 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of ACAT2 mRNA CTD PMID:18032389 NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112 		JBrowse link
G AKR7A3 aldo-keto reductase family 7 member A3 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of AKR7A3 mRNA CTD PMID:20033131 NCBI chr 1:19,274,229...19,288,770
Ensembl chr 1:19,282,573...19,288,770 		JBrowse link
G APOA1 apolipoprotein A1 increases secretion EXP isoquercitrin results in increased secretion of APOA1 protein CTD PMID:24963805 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G ATF6 activating transcription factor 6 increases expression ISO isoquercitrin results in increased expression of ATF6 mRNA CTD PMID:30365939 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574 		JBrowse link
G ATXN2 ataxin 2 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN2 mRNA] CTD PMID:25129099 NCBI chr12:111,452,214...111,599,673
Ensembl chr12:111,443,485...111,599,676 		JBrowse link
G ATXN3 ataxin 3 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN3 mRNA] CTD PMID:25129099 NCBI chr14:92,044,775...92,106,582
Ensembl chr14:92,044,496...92,106,621 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP isoquercitrin results in decreased expression of BCL2 mRNA CTD PMID:30597948 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CASP3 caspase 3 affects expression EXP isoquercitrin affects the expression of CASP3 mRNA CTD PMID:30597948 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP8 caspase 8 decreases expression EXP isoquercitrin results in decreased expression of CASP8 mRNA CTD PMID:30597948 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CAT catalase multiple interactions ISO [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of CAT mRNA; isoquercitrin inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:30298849 PMID:30817903 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCL2 mRNA] CTD PMID:21295105 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions ISO isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CCL5 protein] CTD PMID:14654164 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDKN2B mRNA] CTD PMID:21295105 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305 		JBrowse link
G CTNNB1 catenin beta 1 affects expression EXP isoquercitrin affects the expression of CTNNB1 mRNA CTD PMID:30597948 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 multiple interactions ISO isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CXCL2 protein] CTD PMID:14654164 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression EXP isoquercitrin results in increased expression of CXCL8 mRNA CTD PMID:30597948 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions
decreases activity		 ISO
EXP		 [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A1 mRNA
isoquercitrin results in decreased activity of CYP1A1 protein		 CTD PMID:16271822 PMID:20033131 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A2 mRNA CTD PMID:20033131 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 decreases activity EXP isoquercitrin results in decreased activity of CYP1B1 protein CTD PMID:16271822 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of CYP51A1 mRNA CTD PMID:18032389 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of DHCR7 mRNA CTD PMID:18032389 NCBI chr11:71,434,411...71,448,393
Ensembl chr11:71,428,193...71,452,868 		JBrowse link
G EGF epidermal growth factor multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGFR epidermal growth factor receptor multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:26109002 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of EGLN1 mRNA] CTD PMID:25129099 NCBI chr 1:231,363,756...231,422,287
Ensembl chr 1:231,363,751...231,422,287 		JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDFT1 mRNA CTD PMID:18032389 NCBI chr 8:11,795,582...11,839,309
Ensembl chr 8:11,795,573...11,839,395 		JBrowse link
G FDPS farnesyl diphosphate synthase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDPS mRNA CTD PMID:18032389 NCBI chr 1:155,308,866...155,320,665
Ensembl chr 1:155,308,748...155,320,666 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of FOS mRNA CTD PMID:31068541 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G GPX2 glutathione peroxidase 2 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GPX2 mRNA CTD PMID:20033131 NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746 		JBrowse link
G GRIA3 glutamate ionotropic receptor AMPA type subunit 3 multiple interactions ISO isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of GRIA3 mRNA] CTD PMID:31068541 NCBI chr  X:123,184,278...123,490,915
Ensembl chr  X:123,184,153...123,490,915 		JBrowse link
G GSTA5 glutathione S-transferase alpha 5 multiple interactions ISO [isoquercitrin co-treated with oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTA5 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 6:52,831,692...52,846,245
Ensembl chr 6:52,831,655...52,840,843 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCR mRNA CTD PMID:18032389 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCS1 mRNA CTD PMID:18032389 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO isoquercitrin inhibits the reaction [beta-Naphthoflavone results in increased expression of HMOX1 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA] CTD PMID:21295105 PMID:30817903 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G IBSP integrin binding sialoprotein increases expression ISO isoquercitrin results in increased expression of IBSP mRNA CTD PMID:30365939 NCBI chr 4:87,799,554...87,812,435
Ensembl chr 4:87,799,554...87,812,435 		JBrowse link
G IL1A interleukin 1 alpha multiple interactions ISO [isoquercitrin analog co-treated with Propylthiouracil] results in increased expression of IL1A mRNA; [isoquercitrin co-treated with Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL1A mRNA CTD PMID:21295105 PMID:31068541 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA] CTD PMID:30817903 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA] CTD PMID:30817903 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of INS1 protein] CTD PMID:30817903 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G INSIG1 insulin induced gene 1 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of INSIG1 mRNA CTD PMID:18032389 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235 		JBrowse link
G JAK1 Janus kinase 1 increases expression EXP isoquercitrin results in increased expression of JAK1 mRNA CTD PMID:30597948 NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754 		JBrowse link
G JAK2 Janus kinase 2 increases expression EXP isoquercitrin results in increased expression of JAK2 mRNA CTD PMID:30597948 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA] CTD PMID:30817903 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G LCT lactase multiple interactions ISO [migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of isoquercitrin CTD PMID:12663055 NCBI chr 2:135,787,850...135,837,184
Ensembl chr 2:135,787,850...135,837,184 		JBrowse link
G LDLR low density lipoprotein receptor multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of LDLR mRNA CTD PMID:18032389 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein] CTD PMID:26109002 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:26109002 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member affects expression EXP isoquercitrin affects the expression of MCL1 mRNA CTD PMID:30597948 NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738 		JBrowse link
G ME1 malic enzyme 1 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNA] CTD PMID:20033131 NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions EXP isoquercitrin results in decreased expression of and results in decreased activity of MMP2 protein CTD PMID:18715546 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions EXP isoquercitrin results in decreased expression of and results in decreased activity of MMP9 protein CTD PMID:18715546 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA] CTD PMID:30817903 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions ISO [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of NFKB1 mRNA CTD PMID:31068541 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NFKBIA mRNA] CTD PMID:20045035 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NOS2 mRNA] CTD PMID:21295105 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of NQO1 mRNA; isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of NQO1 mRNA] CTD PMID:20033131 PMID:31068541 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 multiple interactions ISO [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of NR3C2 mRNA CTD PMID:30298849 NCBI chr 4:148,078,764...148,445,508
Ensembl chr 4:148,078,762...148,444,698 		JBrowse link
G NSF N-ethylmaleimide sensitive factor, vesicle fusing ATPase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSF mRNA] CTD PMID:25129099 NCBI chr17:46,590,669...46,757,464
Ensembl chr17:46,590,669...46,757,679 		JBrowse link
G NSG1 neuronal vesicle trafficking associated 1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSG1 mRNA] CTD PMID:25129099 NCBI chr 4:4,386,532...4,419,058
Ensembl chr 4:4,348,140...4,419,058 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of OPA1 mRNA] CTD PMID:25129099 NCBI chr 3:193,593,208...193,697,811
Ensembl chr 3:193,593,144...193,697,811 		JBrowse link
G OTX2 orthodenticle homeobox 2 multiple interactions ISO isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of OTX2 mRNA] CTD PMID:31068541 NCBI chr14:56,799,905...56,810,479
Ensembl chr14:56,799,905...56,816,693 		JBrowse link
G PARK7 Parkinsonism associated deglycase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PARK7 mRNA] CTD PMID:25129099 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha affects expression EXP isoquercitrin affects the expression of PIK3CA mRNA CTD PMID:30597948 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 increases expression EXP isoquercitrin results in increased expression of PIK3R1 mRNA CTD PMID:30597948 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
G PPID peptidylprolyl isomerase D multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PPID mRNA] CTD PMID:25129099 NCBI chr 4:158,709,127...158,723,396
Ensembl chr 4:158,709,127...158,723,396 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] CTD PMID:25129099 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA] CTD PMID:14654164 PMID:20045035 PMID:30817903 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTK2 protein tyrosine kinase 2 multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216 		JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit increases expression EXP isoquercitrin results in increased expression of RELB mRNA CTD PMID:30597948 NCBI chr19:45,001,464...45,038,192
Ensembl chr19:45,001,461...45,038,192 		JBrowse link
G RUNX2 RUNX family transcription factor 2 increases expression ISO isoquercitrin results in increased expression of RUNX2 mRNA CTD PMID:30365939 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349 		JBrowse link
G SC5D sterol-C5-desaturase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SC5D mRNA CTD PMID:18032389 NCBI chr11:121,292,771...121,313,410
Ensembl chr11:121,292,681...121,313,410 		JBrowse link
G SERPINE1 serpin family E member 1 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA] CTD PMID:20045035 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SLC5A1 solute carrier family 5 member 1 multiple interactions EXP isoquercitrin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside] CTD PMID:17495124 NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029 		JBrowse link
G SQLE squalene epoxidase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SQLE mRNA CTD PMID:18032389 NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased cleavage of and results in increased activity of SREBF2 protein; [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SREBF2 mRNA; SREBF2 protein affects the susceptibility to [isoquercitrin co-treated with Hydrogen Peroxide] CTD PMID:18032389 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 increases expression EXP isoquercitrin results in increased expression of STAT3 mRNA CTD PMID:30597948 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STAT6 signal transducer and activator of transcription 6 increases expression EXP isoquercitrin results in increased expression of STAT6 mRNA CTD PMID:30597948 NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of STUB1 mRNA] CTD PMID:25129099 NCBI chr16:680,410...682,801
Ensembl chr16:680,224...682,870 		JBrowse link
G TH tyrosine hydroxylase multiple interactions ISO isoquercitrin promotes the reaction [Oxidopamine results in decreased expression of TH mRNA] CTD PMID:25129099 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 increases expression EXP isoquercitrin results in increased expression of TIMP1 protein CTD PMID:18715546 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNF mRNA]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] CTD PMID:14654164 PMID:21295105 PMID:30817903 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF1A protein] CTD PMID:21295105 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TP53 tumor protein p53 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA] CTD PMID:30817903 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G TRADD TNFRSF1A associated via death domain multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TRADD protein] CTD PMID:21295105 NCBI chr16:67,154,185...67,159,909
Ensembl chr16:67,154,185...67,159,909 		JBrowse link
G TXN thioredoxin multiple interactions ISO isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of TXN1 mRNA] CTD PMID:31068541 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
G TYK2 tyrosine kinase 2 affects expression EXP isoquercitrin affects the expression of TYK2 mRNA CTD PMID:30597948 NCBI chr19:10,350,533...10,380,572
Ensembl chr19:10,350,533...10,380,608 		JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of UCHL1 mRNA] CTD PMID:25129099 NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455 		JBrowse link
quercetin 3-O-beta-D-glucopyranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT2 acetyl-CoA acetyltransferase 2 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of ACAT2 mRNA CTD PMID:18032389 NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112 		JBrowse link
G AKR7A3 aldo-keto reductase family 7 member A3 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of AKR7A3 mRNA CTD PMID:20033131 NCBI chr 1:19,274,229...19,288,770
Ensembl chr 1:19,282,573...19,288,770 		JBrowse link
G APOA1 apolipoprotein A1 increases secretion EXP isoquercitrin results in increased secretion of APOA1 protein CTD PMID:24963805 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G ATF6 activating transcription factor 6 increases expression ISO isoquercitrin results in increased expression of ATF6 mRNA CTD PMID:30365939 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574 		JBrowse link
G ATXN2 ataxin 2 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN2 mRNA] CTD PMID:25129099 NCBI chr12:111,452,214...111,599,673
Ensembl chr12:111,443,485...111,599,676 		JBrowse link
G ATXN3 ataxin 3 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN3 mRNA] CTD PMID:25129099 NCBI chr14:92,044,775...92,106,582
Ensembl chr14:92,044,496...92,106,621 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP isoquercitrin results in decreased expression of BCL2 mRNA CTD PMID:30597948 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CASP3 caspase 3 affects expression EXP isoquercitrin affects the expression of CASP3 mRNA CTD PMID:30597948 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP8 caspase 8 decreases expression EXP isoquercitrin results in decreased expression of CASP8 mRNA CTD PMID:30597948 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CAT catalase multiple interactions ISO [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of CAT mRNA; isoquercitrin inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:30298849 PMID:30817903 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCL2 mRNA] CTD PMID:21295105 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions ISO isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CCL5 protein] CTD PMID:14654164 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDKN2B mRNA] CTD PMID:21295105 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305 		JBrowse link
G CTNNB1 catenin beta 1 affects expression EXP isoquercitrin affects the expression of CTNNB1 mRNA CTD PMID:30597948 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 multiple interactions ISO isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CXCL2 protein] CTD PMID:14654164 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression EXP isoquercitrin results in increased expression of CXCL8 mRNA CTD PMID:30597948 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 decreases activity
multiple interactions		 EXP
ISO		 isoquercitrin results in decreased activity of CYP1A1 protein
[Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A1 mRNA		 CTD PMID:16271822 PMID:20033131 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A2 mRNA CTD PMID:20033131 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 decreases activity EXP isoquercitrin results in decreased activity of CYP1B1 protein CTD PMID:16271822 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of CYP51A1 mRNA CTD PMID:18032389 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of DHCR7 mRNA CTD PMID:18032389 NCBI chr11:71,434,411...71,448,393
Ensembl chr11:71,428,193...71,452,868 		JBrowse link
G EGF epidermal growth factor multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGFR epidermal growth factor receptor multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:26109002 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of EGLN1 mRNA] CTD PMID:25129099 NCBI chr 1:231,363,756...231,422,287
Ensembl chr 1:231,363,751...231,422,287 		JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDFT1 mRNA CTD PMID:18032389 NCBI chr 8:11,795,582...11,839,309
Ensembl chr 8:11,795,573...11,839,395 		JBrowse link
G FDPS farnesyl diphosphate synthase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDPS mRNA CTD PMID:18032389 NCBI chr 1:155,308,866...155,320,665
Ensembl chr 1:155,308,748...155,320,666 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of FOS mRNA CTD PMID:31068541 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G GPX2 glutathione peroxidase 2 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GPX2 mRNA CTD PMID:20033131 NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746 		JBrowse link
G GRIA3 glutamate ionotropic receptor AMPA type subunit 3 multiple interactions ISO isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of GRIA3 mRNA] CTD PMID:31068541 NCBI chr  X:123,184,278...123,490,915
Ensembl chr  X:123,184,153...123,490,915 		JBrowse link
G GSTA5 glutathione S-transferase alpha 5 multiple interactions ISO [isoquercitrin co-treated with oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTA5 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 6:52,831,692...52,846,245
Ensembl chr 6:52,831,655...52,840,843 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCR mRNA CTD PMID:18032389 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCS1 mRNA CTD PMID:18032389 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO isoquercitrin inhibits the reaction [beta-Naphthoflavone results in increased expression of HMOX1 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA] CTD PMID:21295105 PMID:30817903 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G IBSP integrin binding sialoprotein increases expression ISO isoquercitrin results in increased expression of IBSP mRNA CTD PMID:30365939 NCBI chr 4:87,799,554...87,812,435
Ensembl chr 4:87,799,554...87,812,435 		JBrowse link
G IL1A interleukin 1 alpha multiple interactions ISO [isoquercitrin analog co-treated with Propylthiouracil] results in increased expression of IL1A mRNA; [isoquercitrin co-treated with Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL1A mRNA CTD PMID:21295105 PMID:31068541 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA] CTD PMID:30817903 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA] CTD PMID:30817903 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of INS1 protein] CTD PMID:30817903 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G INSIG1 insulin induced gene 1 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of INSIG1 mRNA CTD PMID:18032389 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235 		JBrowse link
G JAK1 Janus kinase 1 increases expression EXP isoquercitrin results in increased expression of JAK1 mRNA CTD PMID:30597948 NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754 		JBrowse link
G JAK2 Janus kinase 2 increases expression EXP isoquercitrin results in increased expression of JAK2 mRNA CTD PMID:30597948 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA] CTD PMID:30817903 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G LCT lactase multiple interactions ISO [migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of isoquercitrin CTD PMID:12663055 NCBI chr 2:135,787,850...135,837,184
Ensembl chr 2:135,787,850...135,837,184 		JBrowse link
G LDLR low density lipoprotein receptor multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of LDLR mRNA CTD PMID:18032389 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein] CTD PMID:26109002 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:26109002 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member affects expression EXP isoquercitrin affects the expression of MCL1 mRNA CTD PMID:30597948 NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738 		JBrowse link
G ME1 malic enzyme 1 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNA] CTD PMID:20033131 NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions EXP isoquercitrin results in decreased expression of and results in decreased activity of MMP2 protein CTD PMID:18715546 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions EXP isoquercitrin results in decreased expression of and results in decreased activity of MMP9 protein CTD PMID:18715546 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA] CTD PMID:30817903 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions ISO [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of NFKB1 mRNA CTD PMID:31068541 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NFKBIA mRNA] CTD PMID:20045035 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NOS2 mRNA] CTD PMID:21295105 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of NQO1 mRNA; isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of NQO1 mRNA] CTD PMID:20033131 PMID:31068541 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 multiple interactions ISO [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of NR3C2 mRNA CTD PMID:30298849 NCBI chr 4:148,078,764...148,445,508
Ensembl chr 4:148,078,762...148,444,698 		JBrowse link
G NSF N-ethylmaleimide sensitive factor, vesicle fusing ATPase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSF mRNA] CTD PMID:25129099 NCBI chr17:46,590,669...46,757,464
Ensembl chr17:46,590,669...46,757,679 		JBrowse link
G NSG1 neuronal vesicle trafficking associated 1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSG1 mRNA] CTD PMID:25129099 NCBI chr 4:4,386,532...4,419,058
Ensembl chr 4:4,348,140...4,419,058 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of OPA1 mRNA] CTD PMID:25129099 NCBI chr 3:193,593,208...193,697,811
Ensembl chr 3:193,593,144...193,697,811 		JBrowse link
G OTX2 orthodenticle homeobox 2 multiple interactions ISO isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of OTX2 mRNA] CTD PMID:31068541 NCBI chr14:56,799,905...56,810,479
Ensembl chr14:56,799,905...56,816,693 		JBrowse link
G PARK7 Parkinsonism associated deglycase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PARK7 mRNA] CTD PMID:25129099 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha affects expression EXP isoquercitrin affects the expression of PIK3CA mRNA CTD PMID:30597948 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 increases expression EXP isoquercitrin results in increased expression of PIK3R1 mRNA CTD PMID:30597948 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
G PPID peptidylprolyl isomerase D multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PPID mRNA] CTD PMID:25129099 NCBI chr 4:158,709,127...158,723,396
Ensembl chr 4:158,709,127...158,723,396 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] CTD PMID:25129099 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA] CTD PMID:14654164 PMID:20045035 PMID:30817903 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTK2 protein tyrosine kinase 2 multiple interactions EXP isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216 		JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit increases expression EXP isoquercitrin results in increased expression of RELB mRNA CTD PMID:30597948 NCBI chr19:45,001,464...45,038,192
Ensembl chr19:45,001,461...45,038,192 		JBrowse link
G RUNX2 RUNX family transcription factor 2 increases expression ISO isoquercitrin results in increased expression of RUNX2 mRNA CTD PMID:30365939 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349 		JBrowse link
G SC5D sterol-C5-desaturase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SC5D mRNA CTD PMID:18032389 NCBI chr11:121,292,771...121,313,410
Ensembl chr11:121,292,681...121,313,410 		JBrowse link
G SERPINE1 serpin family E member 1 multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA] CTD PMID:20045035 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SLC5A1 solute carrier family 5 member 1 multiple interactions EXP isoquercitrin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside] CTD PMID:17495124 NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029 		JBrowse link
G SQLE squalene epoxidase multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SQLE mRNA CTD PMID:18032389 NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 multiple interactions EXP [isoquercitrin co-treated with Hydrogen Peroxide] results in increased cleavage of and results in increased activity of SREBF2 protein; [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SREBF2 mRNA; SREBF2 protein affects the susceptibility to [isoquercitrin co-treated with Hydrogen Peroxide] CTD PMID:18032389 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 increases expression EXP isoquercitrin results in increased expression of STAT3 mRNA CTD PMID:30597948 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STAT6 signal transducer and activator of transcription 6 increases expression EXP isoquercitrin results in increased expression of STAT6 mRNA CTD PMID:30597948 NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of STUB1 mRNA] CTD PMID:25129099 NCBI chr16:680,410...682,801
Ensembl chr16:680,224...682,870 		JBrowse link
G TH tyrosine hydroxylase multiple interactions ISO isoquercitrin promotes the reaction [Oxidopamine results in decreased expression of TH mRNA] CTD PMID:25129099 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 increases expression EXP isoquercitrin results in increased expression of TIMP1 protein CTD PMID:18715546 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNF mRNA]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] CTD PMID:14654164 PMID:21295105 PMID:30817903 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF1A protein] CTD PMID:21295105 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TP53 tumor protein p53 multiple interactions ISO isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA] CTD PMID:30817903 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G TRADD TNFRSF1A associated via death domain multiple interactions ISO isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TRADD protein] CTD PMID:21295105 NCBI chr16:67,154,185...67,159,909
Ensembl chr16:67,154,185...67,159,909 		JBrowse link
G TXN thioredoxin multiple interactions ISO isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of TXN1 mRNA] CTD PMID:31068541 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
G TYK2 tyrosine kinase 2 affects expression EXP isoquercitrin affects the expression of TYK2 mRNA CTD PMID:30597948 NCBI chr19:10,350,533...10,380,572
Ensembl chr19:10,350,533...10,380,608 		JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 multiple interactions ISO isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of UCHL1 mRNA] CTD PMID:25129099 NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455 		JBrowse link
quercetin 4'-O-beta-D-glucopyranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein] CTD PMID:32602595 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G AP5M1 adaptor related protein complex 5 subunit mu 1 decreases expression EXP spiraeoside results in decreased expression of AP5M1 protein CTD PMID:34116102 NCBI chr14:57,268,971...57,298,742
Ensembl chr14:57,268,924...57,298,742 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in increased expression of BAX protein]]; spiraeoside inhibits the reaction [Glucose results in increased expression of BAX protein] CTD PMID:32602595 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression		 EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of BCL2 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased expression of BCL2 protein]
spiraeoside results in decreased expression of BCL2 protein		 CTD PMID:32602595 PMID:34116102 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BID BH3 interacting domain death agonist decreases expression EXP spiraeoside results in decreased expression of BID protein CTD PMID:34116102 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G CASP3 caspase 3 decreases expression EXP spiraeoside results in decreased expression of CASP3 protein CTD PMID:34116102 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 decreases expression EXP spiraeoside results in decreased expression of CASP9 protein CTD PMID:34116102 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in increased activity of CAT protein]]; spiraeoside inhibits the reaction [Glucose results in increased activity of CAT protein] CTD PMID:32602595 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CDK2 cyclin dependent kinase 2 decreases expression EXP spiraeoside results in decreased expression of CDK2 protein CTD PMID:34116102 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789 		JBrowse link
G CRYZ crystallin zeta increases activity ISO spiraeoside results in increased activity of CRYZ protein CTD PMID:8968052 NCBI chr 1:74,705,486...74,733,050
Ensembl chr 1:74,705,482...74,733,408 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of HMOX1 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased expression of HMOX1 protein] CTD PMID:32602595 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G LCT lactase multiple interactions ISO [migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of spiraeoside CTD PMID:12663055 NCBI chr 2:135,787,850...135,837,184
Ensembl chr 2:135,787,850...135,837,184 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein] CTD PMID:32602595 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G PLCG2 phospholipase C gamma 2 decreases phosphorylation EXP spiraeoside results in decreased phosphorylation of PLCG2 protein CTD PMID:15613018 NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,779,279...81,962,685 		JBrowse link
G SLC5A1 solute carrier family 5 member 1 multiple interactions ISO
EXP		 [Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of spiraeoside
spiraeoside inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside]		 CTD PMID:12663055 PMID:17495124 NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029 		JBrowse link
G SYK spleen associated tyrosine kinase decreases phosphorylation EXP spiraeoside results in decreased phosphorylation of SYK protein CTD PMID:15613018 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549 		JBrowse link
quercitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions EXP quercitrin promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]] CTD PMID:34217736 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) decreases expression EXP quercitrin results in decreased expression of ABCC4 mRNA CTD PMID:25193878 NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475 		JBrowse link
G ABCF2 ATP binding cassette subfamily F member 2 increases expression EXP quercitrin results in increased expression of ABCF2 mRNA CTD PMID:25193878 NCBI chr 7:151,211,484...151,227,205
Ensembl chr 7:151,211,484...151,227,205 		JBrowse link
G ACBD6 acyl-CoA binding domain containing 6 decreases expression EXP quercitrin results in decreased expression of ACBD6 mRNA CTD PMID:25193878 NCBI chr 1:180,269,653...180,502,577
Ensembl chr 1:180,269,653...180,502,954 		JBrowse link
G ACBD7 acyl-CoA binding domain containing 7 increases expression EXP quercitrin results in increased expression of ACBD7 mRNA CTD PMID:25193878 NCBI chr10:15,075,475...15,088,776
Ensembl chr10:15,075,475...15,088,776 		JBrowse link
G ACTN1 actinin alpha 1 affects expression EXP quercitrin affects the expression of ACTN1 mRNA CTD PMID:25193878 NCBI chr14:68,874,128...68,979,302
Ensembl chr14:68,874,128...68,979,440 		JBrowse link
G ACTN4 actinin alpha 4 affects expression EXP quercitrin affects the expression of ACTN4 mRNA CTD PMID:25193878 NCBI chr19:38,647,649...38,731,589
Ensembl chr19:38,647,649...38,731,589 		JBrowse link
G ADGRB1 adhesion G protein-coupled receptor B1 decreases expression EXP quercitrin results in decreased expression of ADGRB1 mRNA CTD PMID:25193878 NCBI chr 8:142,449,649...142,545,007
Ensembl chr 8:142,449,430...142,545,009 		JBrowse link
G ADGRF1 adhesion G protein-coupled receptor F1 decreases expression EXP quercitrin results in decreased expression of ADGRF1 mRNA CTD PMID:25193878 NCBI chr 6:46,997,708...47,042,332
Ensembl chr 6:46,997,708...47,042,350 		JBrowse link
G ADGRG1 adhesion G protein-coupled receptor G1 decreases expression EXP quercitrin results in decreased expression of ADGRG1 mRNA CTD PMID:25193878 NCBI chr16:57,619,738...57,665,567
Ensembl chr16:57,610,652...57,665,580 		JBrowse link
G ADGRG6 adhesion G protein-coupled receptor G6 decreases expression EXP quercitrin results in decreased expression of ADGRG6 mRNA CTD PMID:25193878 NCBI chr 6:142,302,007...142,446,261
Ensembl chr 6:142,301,854...142,446,266 		JBrowse link
G ADGRG7 adhesion G protein-coupled receptor G7 increases expression EXP quercitrin results in increased expression of ADGRG7 mRNA CTD PMID:25193878 NCBI chr 3:100,609,601...100,695,479
Ensembl chr 3:100,609,601...100,695,479 		JBrowse link
G ADGRV1 adhesion G protein-coupled receptor V1 increases expression EXP quercitrin results in increased expression of ADGRV1 mRNA CTD PMID:25193878 NCBI chr 5:90,558,797...91,164,437
Ensembl chr 5:90,529,344...91,164,437 		JBrowse link
G ADK adenosine kinase decreases expression EXP quercitrin results in decreased expression of ADK mRNA CTD PMID:25193878 NCBI chr10:74,151,221...74,709,290
Ensembl chr10:74,151,202...74,709,963 		JBrowse link
G ADRA2C adrenoceptor alpha 2C increases expression EXP quercitrin results in increased expression of ADRA2C mRNA CTD PMID:25193878 NCBI chr 4:3,766,385...3,768,526
Ensembl chr 4:3,766,348...3,768,526 		JBrowse link
G AHNAK2 AHNAK nucleoprotein 2 increases expression EXP quercitrin results in increased expression of AHNAK2 mRNA CTD PMID:25193878 NCBI chr14:104,937,253...104,978,374
Ensembl chr14:104,937,244...104,978,374 		JBrowse link
G ALKBH7 alkB homolog 7 increases expression EXP quercitrin results in increased expression of ALKBH7 mRNA CTD PMID:25193878 NCBI chr19:6,372,794...6,375,250
Ensembl chr19:6,372,794...6,375,250 		JBrowse link
G ANAPC15 anaphase promoting complex subunit 15 decreases expression EXP quercitrin results in decreased expression of ANAPC15 mRNA CTD PMID:25193878 NCBI chr11:72,106,372...72,112,780
Ensembl chr11:72,106,378...72,112,780 		JBrowse link
G AR androgen receptor increases expression EXP quercitrin results in increased expression of AR mRNA CTD PMID:25193878 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 increases expression EXP quercitrin results in increased expression of ARAP2 mRNA CTD PMID:25193878 NCBI chr 4:36,005,404...36,244,784
Ensembl chr 4:35,948,221...36,244,514 		JBrowse link
G ASB6 ankyrin repeat and SOCS box containing 6 increases expression EXP quercitrin results in increased expression of ASB6 mRNA CTD PMID:25193878 NCBI chr 9:129,634,605...129,642,151
Ensembl chr 9:129,634,604...129,642,169 		JBrowse link
G ATG7 autophagy related 7 decreases expression EXP quercitrin results in decreased expression of ATG7 mRNA CTD PMID:25193878 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665 		JBrowse link
G BAIAP2 BAR/IMD domain containing adaptor protein 2 affects expression EXP quercitrin affects the expression of BAIAP2 mRNA CTD PMID:25193878 NCBI chr17:81,035,151...81,117,434
Ensembl chr17:81,035,122...81,117,434 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of BAX protein] CTD PMID:23138875 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BDKRB1 bradykinin receptor B1 decreases expression EXP quercitrin results in decreased expression of BDKRB1 mRNA CTD PMID:25193878 NCBI chr14:96,256,210...96,264,763
Ensembl chr14:96,256,210...96,268,967 		JBrowse link
G C2orf49 chromosome 2 open reading frame 49 decreases expression EXP quercitrin results in decreased expression of C2ORF49 mRNA CTD PMID:25193878 NCBI chr 2:105,337,540...105,385,899
Ensembl chr 2:105,337,532...105,349,211 		JBrowse link
G CAMK2B calcium/calmodulin dependent protein kinase II beta decreases expression EXP quercitrin results in decreased expression of CAMK2B mRNA CTD PMID:25193878 NCBI chr 7:44,217,154...44,326,013
Ensembl chr 7:44,210,019...44,334,577 		JBrowse link
G CASP3 caspase 3 increases activity
multiple interactions		 EXP
ISO		 quercitrin results in increased activity of CASP3 protein
quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of CASP3 protein]		 CTD PMID:23138875 PMID:25193878 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP8 caspase 8 increases expression EXP quercitrin results in increased expression of CASP8 mRNA CTD PMID:25193878 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CCR9 C-C motif chemokine receptor 9 decreases expression EXP quercitrin results in decreased expression of CCR9 mRNA CTD PMID:25193878 NCBI chr 3:45,886,064...45,903,174
Ensembl chr 3:45,884,425...45,903,174 		JBrowse link
G CCRL2 C-C motif chemokine receptor like 2 increases expression EXP quercitrin results in increased expression of CCRL2 mRNA CTD PMID:25193878 NCBI chr 3:46,407,259...46,409,523
Ensembl chr 3:46,407,166...46,412,997 		JBrowse link
G CD302 CD302 molecule decreases expression EXP quercitrin results in decreased expression of CD302 mRNA CTD PMID:25193878 NCBI chr 2:159,768,628...159,798,208
Ensembl chr 2:159,768,628...159,798,255 		JBrowse link
G CD38 CD38 molecule decreases expression EXP quercitrin results in decreased expression of CD38 mRNA CTD PMID:25193878 NCBI chr 4:15,778,328...15,853,232
Ensembl chr 4:15,778,275...15,853,232 		JBrowse link
G CD74 CD74 molecule affects expression EXP quercitrin affects the expression of CD74 mRNA CTD PMID:25193878 NCBI chr 5:150,401,639...150,412,910
Ensembl chr 5:150,401,637...150,412,969 		JBrowse link
G CDH1 cadherin 1 decreases expression EXP quercitrin results in decreased expression of CDH1 mRNA CTD PMID:25193878 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CDKN3 cyclin dependent kinase inhibitor 3 decreases expression EXP quercitrin results in decreased expression of CDKN3 mRNA CTD PMID:25193878 NCBI chr14:54,397,007...54,420,218
Ensembl chr14:54,396,849...54,420,218 		JBrowse link
G CELSR3 cadherin EGF LAG seven-pass G-type receptor 3 increases expression EXP quercitrin results in increased expression of CELSR3 mRNA CTD PMID:25193878 NCBI chr 3:48,636,463...48,662,886
Ensembl chr 3:48,636,463...48,662,886 		JBrowse link
G CEP95 centrosomal protein 95 increases expression EXP quercitrin results in increased expression of CEP95 mRNA CTD PMID:25193878 NCBI chr17:64,506,762...64,537,946
Ensembl chr17:64,506,865...64,542,461 		JBrowse link
G CERS5 ceramide synthase 5 increases expression EXP quercitrin results in increased expression of CERS5 mRNA CTD PMID:25193878 NCBI chr12:50,129,289...50,167,369
Ensembl chr12:50,129,289...50,167,533 		JBrowse link
G CFAP298 cilia and flagella associated protein 298 decreases expression EXP quercitrin results in decreased expression of CFAP298 mRNA CTD PMID:25193878 NCBI chr21:32,599,354...32,612,377
Ensembl chr21:32,592,079...32,612,603 		JBrowse link
G CHD2 chromodomain helicase DNA binding protein 2 decreases expression EXP quercitrin results in decreased expression of CHD2 mRNA CTD PMID:25193878 NCBI chr15:92,900,324...93,027,996
Ensembl chr15:92,886,203...93,027,996 		JBrowse link
G CLDN10 claudin 10 affects expression EXP quercitrin affects the expression of CLDN10 mRNA CTD PMID:25193878 NCBI chr13:95,433,755...95,579,759
Ensembl chr13:95,433,604...95,579,759 		JBrowse link
G CLDN23 claudin 23 affects expression EXP quercitrin affects the expression of CLDN23 mRNA CTD PMID:25193878 NCBI chr 8:8,701,937...8,704,096
Ensembl chr 8:8,701,937...8,704,096 		JBrowse link
G CLDN4 claudin 4 affects expression EXP quercitrin affects the expression of CLDN4 mRNA CTD PMID:25193878 NCBI chr 7:73,830,996...73,832,690
Ensembl chr 7:73,799,542...73,832,690 		JBrowse link
G CLDN8 claudin 8 affects expression EXP quercitrin affects the expression of CLDN8 mRNA CTD PMID:25193878 NCBI chr21:30,214,006...30,216,097
Ensembl chr21:30,214,006...30,216,097 		JBrowse link
G COL3A1 collagen type III alpha 1 chain decreases expression EXP quercitrin results in decreased expression of COL3A1 mRNA CTD PMID:25193878 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746 		JBrowse link
G COQ3 coenzyme Q3, methyltransferase decreases expression EXP quercitrin results in decreased expression of COQ3 mRNA CTD PMID:25193878 NCBI chr 6:99,369,401...99,394,195
Ensembl chr 6:99,369,401...99,394,195 		JBrowse link
G CRISP1 cysteine rich secretory protein 1 decreases expression EXP quercitrin results in decreased expression of CRISP1 mRNA CTD PMID:25193878 NCBI chr 6:49,834,257...49,877,096
Ensembl chr 6:49,834,257...49,877,096 		JBrowse link
G CRYZL1 crystallin zeta like 1 decreases expression EXP quercitrin results in decreased expression of CRYZL1 mRNA CTD PMID:25193878 NCBI chr21:33,589,341...33,641,741
Ensembl chr21:33,589,341...33,643,926 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 affects expression EXP quercitrin affects the expression of CSNK2A1 mRNA CTD PMID:25193878 NCBI chr20:472,498...543,790
Ensembl chr20:472,498...543,835 		JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 affects expression EXP quercitrin affects the expression of CSNK2A2 mRNA CTD PMID:25193878 NCBI chr16:58,157,907...58,198,106
Ensembl chr16:58,157,907...58,198,106 		JBrowse link
G CTDSPL2 CTD small phosphatase like 2 decreases expression EXP quercitrin results in decreased expression of CTDSPL2 mRNA CTD PMID:25193878 NCBI chr15:44,427,629...44,529,038
Ensembl chr15:44,427,622...44,529,038 		JBrowse link
G CTSB cathepsin B affects expression EXP quercitrin affects the expression of CTSB mRNA CTD PMID:25193878 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 decreases activity EXP quercitrin results in decreased activity of CYP1A1 protein CTD PMID:16271822 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 decreases activity EXP quercitrin results in decreased activity of CYP1B1 protein CTD PMID:16271822 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G CYP26B1 cytochrome P450 family 26 subfamily B member 1 increases expression EXP quercitrin results in increased expression of CYP26B1 mRNA CTD PMID:25193878 NCBI chr 2:72,129,238...72,147,862
Ensembl chr 2:72,129,238...72,147,862 		JBrowse link
G DCUN1D5 defective in cullin neddylation 1 domain containing 5 decreases expression EXP quercitrin results in decreased expression of DCUN1D5 mRNA CTD PMID:25193878 NCBI chr11:103,050,686...103,092,160
Ensembl chr11:103,050,686...103,092,194 		JBrowse link
G DDX19B DEAD-box helicase 19B decreases expression EXP quercitrin results in decreased expression of DDX19B mRNA CTD PMID:25193878 NCBI chr16:70,289,767...70,335,305
Ensembl chr16:70,289,663...70,335,305 		JBrowse link
G DELE1 DAP3 binding cell death enhancer 1 decreases expression EXP quercitrin results in decreased expression of DELE1 mRNA CTD PMID:25193878 NCBI chr 5:141,923,871...141,942,047
Ensembl chr 5:141,923,855...141,942,047 		JBrowse link
G DGKQ diacylglycerol kinase theta affects expression EXP quercitrin affects the expression of DGKQ mRNA CTD PMID:25193878 NCBI chr 4:958,887...973,569
Ensembl chr 4:958,887...986,895 		JBrowse link
G DHRS11 dehydrogenase/reductase 11 decreases activity EXP quercitrin results in decreased activity of DHRS11 protein CTD PMID:30926317 NCBI chr17:36,591,879...36,600,804
Ensembl chr17:36,591,879...36,600,804 		JBrowse link
G DTWD1 DTW domain containing 1 decreases expression EXP quercitrin results in decreased expression of DTWD1 mRNA CTD PMID:25193878 NCBI chr15:49,621,048...49,656,232
Ensembl chr15:49,621,037...49,656,232 		JBrowse link
G EEIG1 estrogen-induced osteoclastogenesis regulator 1 increases expression EXP quercitrin results in increased expression of EEIG1 mRNA CTD PMID:25193878 NCBI chr 9:127,940,582...127,980,989
Ensembl chr 9:127,940,582...127,980,989 		JBrowse link
G EGR2 early growth response 2 increases expression EXP quercitrin results in increased expression of EGR2 mRNA CTD PMID:25193878 NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,819,167 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 increases expression EXP quercitrin results in increased expression of EPAS1 mRNA CTD PMID:25193878 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697 		JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit decreases expression EXP quercitrin results in decreased expression of ERCC1 mRNA CTD PMID:25193878 NCBI chr19:45,407,334...45,451,547
Ensembl chr19:45,407,334...45,478,828 		JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression EXP quercitrin results in decreased expression of ERCC2 mRNA CTD PMID:25193878 NCBI chr19:45,349,837...45,370,573
Ensembl chr19:45,349,837...45,370,918 		JBrowse link
G ERI2 ERI1 exoribonuclease family member 2 increases expression EXP quercitrin results in increased expression of ERI2 mRNA CTD PMID:25193878 NCBI chr16:20,780,193...20,806,472
Ensembl chr16:20,780,193...20,900,349 		JBrowse link
G EVA1A eva-1 homolog A, regulator of programmed cell death decreases expression EXP quercitrin results in decreased expression of EVA1A mRNA CTD PMID:25193878 NCBI chr 2:75,492,318...75,569,719
Ensembl chr 2:75,469,302...75,569,722 		JBrowse link
G F11R F11 receptor affects expression EXP quercitrin affects the expression of F11R mRNA CTD PMID:25193878 NCBI chr 1:160,995,211...161,021,152
Ensembl chr 1:160,995,211...161,021,175 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 increases expression EXP quercitrin results in increased expression of F2RL1 mRNA CTD PMID:25193878 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G F2RL2 coagulation factor II thrombin receptor like 2 decreases expression EXP quercitrin results in decreased expression of F2RL2 mRNA CTD PMID:25193878 NCBI chr 5:76,615,482...76,623,403
Ensembl chr 5:76,615,482...76,623,413 		JBrowse link
G F3 coagulation factor III, tissue factor increases expression EXP quercitrin results in increased expression of F3 mRNA CTD PMID:25193878 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759 		JBrowse link
G FAHD2A fumarylacetoacetate hydrolase domain containing 2A decreases expression EXP quercitrin results in decreased expression of FAHD2A mRNA CTD PMID:25193878 NCBI chr 2:95,402,708...95,421,656
Ensembl chr 2:95,402,708...95,416,616 		JBrowse link
G FAIM Fas apoptotic inhibitory molecule increases expression EXP quercitrin results in increased expression of FAIM mRNA CTD PMID:25193878 NCBI chr 3:138,608,771...138,633,376
Ensembl chr 3:138,608,606...138,633,376 		JBrowse link
G FAM216A family with sequence similarity 216 member A decreases expression EXP quercitrin results in decreased expression of FAM216A mRNA CTD PMID:25193878 NCBI chr12:110,468,427...110,490,385
Ensembl chr12:110,468,415...110,490,385 		JBrowse link
G FAM3C FAM3 metabolism regulating signaling molecule C increases expression EXP quercitrin results in increased expression of FAM3C mRNA CTD PMID:25193878 NCBI chr 7:121,348,878...121,396,396
Ensembl chr 7:121,348,878...121,396,364 		JBrowse link
G FAM43A family with sequence similarity 43 member A increases expression EXP quercitrin results in increased expression of FAM43A mRNA CTD PMID:25193878 NCBI chr 3:194,685,883...194,689,037
Ensembl chr 3:194,685,883...194,689,037 		JBrowse link
G FAM50A family with sequence similarity 50 member A increases expression EXP quercitrin results in increased expression of FAM50A mRNA CTD PMID:25193878 NCBI chr  X:154,444,141...154,450,654
Ensembl chr  X:154,444,141...154,450,654 		JBrowse link
G FAS Fas cell surface death receptor increases expression EXP quercitrin results in increased expression of FAS mRNA CTD PMID:25193878 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FDCSP follicular dendritic cell secreted protein decreases expression EXP quercitrin results in decreased expression of FDCSP mRNA CTD PMID:25193878 NCBI chr 4:70,226,124...70,235,252
Ensembl chr 4:70,226,124...70,235,252 		JBrowse link
G FLG filaggrin increases expression EXP quercitrin results in increased expression of FLG mRNA CTD PMID:25193878 NCBI chr 1:152,302,165...152,325,239
Ensembl chr 1:152,302,165...152,325,239 		JBrowse link
G FZD4 frizzled class receptor 4 increases expression EXP quercitrin results in increased expression of FZD4 mRNA CTD PMID:25193878 NCBI chr11:86,945,679...86,955,395
Ensembl chr11:86,945,679...86,955,395 		JBrowse link
G GABBR2 gamma-aminobutyric acid type B receptor subunit 2 increases expression EXP quercitrin results in increased expression of GABBR2 mRNA CTD PMID:25193878 NCBI chr 9:98,288,109...98,708,935
Ensembl chr 9:98,288,109...98,708,935 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha affects expression EXP quercitrin affects the expression of GADD45 mRNA CTD PMID:25193878 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GALK2 galactokinase 2 increases expression EXP quercitrin results in increased expression of GALK2 mRNA CTD PMID:25193878 NCBI chr15:49,155,774...49,367,740
Ensembl chr15:49,155,656...49,367,869 		JBrowse link
G GALR3 galanin receptor 3 increases expression EXP quercitrin results in increased expression of GALR3 mRNA CTD PMID:25193878 NCBI chr22:37,823,382...37,825,485
Ensembl chr22:37,823,382...37,825,485 		JBrowse link
G GIMAP6 GTPase, IMAP family member 6 increases expression EXP quercitrin results in increased expression of GIMAP6 mRNA CTD PMID:25193878 NCBI chr 7:150,625,375...150,632,385
Ensembl chr 7:150,625,375...150,632,648 		JBrowse link
G GLIPR1 GLI pathogenesis related 1 decreases expression EXP quercitrin results in decreased expression of GLIPR1 mRNA CTD PMID:25193878 NCBI chr12:75,480,755...75,503,863
Ensembl chr12:75,480,753...75,503,863 		JBrowse link
G GOLIM4 golgi integral membrane protein 4 increases expression EXP quercitrin results in increased expression of GOLIM4 mRNA CTD PMID:25193878 NCBI chr 3:168,008,689...168,095,924
Ensembl chr 3:168,008,689...168,095,924 		JBrowse link
G GPR137B G protein-coupled receptor 137B increases expression EXP quercitrin results in increased expression of GPR137B mRNA CTD PMID:25193878 NCBI chr 1:236,142,539...236,208,907
Ensembl chr 1:236,142,505...236,221,865 		JBrowse link
G GPR173 G protein-coupled receptor 173 increases expression EXP quercitrin results in increased expression of GPR173 mRNA CTD PMID:25193878 NCBI chr  X:53,048,789...53,080,615
Ensembl chr  X:53,048,789...53,080,615 		JBrowse link
G GPR174 G protein-coupled receptor 174 increases expression EXP quercitrin results in increased expression of GPR174 mRNA CTD PMID:25193878 NCBI chr  X:79,144,688...79,175,318
Ensembl chr  X:79,144,688...79,175,318 		JBrowse link
G GPR19 G protein-coupled receptor 19 increases expression EXP quercitrin results in increased expression of GPR19 mRNA CTD PMID:25193878 NCBI chr12:12,660,890...12,717,246
Ensembl chr12:12,660,890...12,696,207 		JBrowse link
G GPR4 G protein-coupled receptor 4 increases expression EXP quercitrin results in increased expression of GPR4 mRNA CTD PMID:25193878 NCBI chr19:45,589,764...45,602,212
Ensembl chr19:45,589,764...45,602,212 		JBrowse link
G GPR63 G protein-coupled receptor 63 increases expression EXP quercitrin results in increased expression of GPR63 mRNA CTD PMID:25193878 NCBI chr 6:96,794,125...96,837,477
Ensembl chr 6:96,794,125...96,837,477 		JBrowse link
G GPR83 G protein-coupled receptor 83 increases expression EXP quercitrin results in increased expression of GPR83 mRNA CTD PMID:25193878 NCBI chr11:94,377,316...94,401,419
Ensembl chr11:94,377,316...94,401,419 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 decreases expression EXP quercitrin results in decreased expression of GSTP1 mRNA CTD PMID:25193878 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 increases expression EXP quercitrin results in increased expression of HAVCR2 mRNA CTD PMID:25193878 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869 		JBrowse link
G HGF hepatocyte growth factor increases expression EXP quercitrin results in increased expression of HGF mRNA CTD PMID:25193878 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438 		JBrowse link
G HLA-A major histocompatibility complex, class I, A affects expression EXP quercitrin affects the expression of HLA-A mRNA CTD PMID:25193878 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572 		JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 affects expression EXP quercitrin affects the expression of HLA-DQA1 mRNA CTD PMID:25193878 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062 		JBrowse link
G HLA-DRB4 major histocompatibility complex, class II, DR beta 4 affects expression EXP quercitrin affects the expression of HLA-DRB4 mRNA CTD PMID:25193878
G HLA-E major histocompatibility complex, class I, E affects expression EXP quercitrin affects the expression of HLA-E mRNA CTD PMID:25193878 NCBI chr 6:30,489,509...30,494,194
Ensembl chr 6:30,489,509...30,494,194 		JBrowse link
G HMGA2 high mobility group AT-hook 2 increases expression EXP quercitrin results in increased expression of HMGA2 mRNA CTD PMID:25193878 NCBI chr12:65,824,460...65,966,291
Ensembl chr12:65,824,460...65,966,291 		JBrowse link
G HMGB2 high mobility group box 2 decreases expression EXP quercitrin results in decreased expression of HMGB2 mRNA CTD PMID:25193878 NCBI chr 4:173,331,376...173,334,358
Ensembl chr 4:173,331,376...173,334,432 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha decreases expression EXP quercitrin results in decreased expression of HNF4A mRNA CTD PMID:25193878 NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 affects expression EXP quercitrin affects the expression of HSP90AA1 mRNA CTD PMID:25193878 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699 		JBrowse link
G HSPA1L heat shock protein family A (Hsp70) member 1 like affects expression EXP quercitrin affects the expression of HSPA1L mRNA CTD PMID:25193878 NCBI chr 6:31,809,619...31,815,283
Ensembl chr 6:31,809,619...31,815,283 		JBrowse link
G HSPA6 heat shock protein family A (Hsp70) member 6 affects expression EXP quercitrin affects the expression of HSPA6 mRNA CTD PMID:25193878 NCBI chr 1:161,524,540...161,526,894
Ensembl chr 1:161,524,540...161,526,894 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 affects expression EXP quercitrin affects the expression of HSPA8 mRNA CTD PMID:25193878 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230 		JBrowse link
G IFNA1 interferon alpha 1 affects expression EXP quercitrin affects the expression of IFNA1 mRNA CTD PMID:25193878 NCBI chr 9:21,440,439...21,441,316
Ensembl chr 9:21,440,439...21,441,316 		JBrowse link
G IFNA6 interferon alpha 6 affects expression EXP quercitrin affects the expression of IFNA6 mRNA CTD PMID:25193878 NCBI chr 9:21,350,318...21,350,887
Ensembl chr 9:21,350,253...21,350,956 		JBrowse link
G IFNG interferon gamma multiple interactions ISO quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of BAX protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of RELA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased cleavage of PARP1 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of CASP3 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:23138875 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IGF1R insulin like growth factor 1 receptor affects expression EXP quercitrin affects the expression of IGF1R mRNA CTD PMID:25193878 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G IL15 interleukin 15 decreases expression EXP quercitrin results in decreased expression of IL15 mRNA CTD PMID:25193878 NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of BAX protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of RELA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased cleavage of PARP1 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of CASP3 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:23138875 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G INO80C INO80 complex subunit C decreases expression EXP quercitrin results in decreased expression of INO80C mRNA CTD PMID:25193878 NCBI chr18:35,468,333...35,497,960
Ensembl chr18:35,452,230...35,497,979 		JBrowse link
G INPP4A inositol polyphosphate-4-phosphatase type I A affects expression EXP quercitrin affects the expression of INPP4A mRNA CTD PMID:25193878 NCBI chr 2:98,444,587...98,594,392
Ensembl chr 2:98,444,854...98,594,392 		JBrowse link
G INPP5D inositol polyphosphate-5-phosphatase D affects expression EXP quercitrin affects the expression of INPP5D mRNA CTD PMID:25193878 NCBI chr 2:233,060,342...233,207,903
Ensembl chr 2:233,059,967...233,207,903 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]] CTD PMID:23138875 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G INSR insulin receptor affects expression EXP quercitrin affects the expression of INSR mRNA CTD PMID:25193878 NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414 		JBrowse link
G IRF2BP2 interferon regulatory factor 2 binding protein 2 increases expression EXP quercitrin results in increased expression of IRF2BP2 mRNA CTD PMID:25193878 NCBI chr 1:234,604,269...234,610,178
Ensembl chr 1:234,604,269...234,610,178 		JBrowse link
G ITGB1 integrin subunit beta 1 affects expression EXP quercitrin affects the expression of ITGB1 mRNA CTD PMID:25193878 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792 		JBrowse link
G JAML junction adhesion molecule like increases expression EXP quercitrin results in increased expression of JAML mRNA CTD PMID:25193878 NCBI chr11:118,193,725...118,225,011
Ensembl chr11:118,193,725...118,225,092 		JBrowse link
G JPT2 Jupiter microtubule associated homolog 2 increases expression EXP quercitrin results in increased expression of JPT2 mRNA CTD PMID:25193878 NCBI chr16:1,678,279...1,702,086
Ensembl chr16:1,678,256...1,702,280 		JBrowse link
G KAT5 lysine acetyltransferase 5 affects expression EXP quercitrin affects the expression of KAT5 mRNA CTD PMID:25193878 NCBI chr11:65,712,018...65,719,604
Ensembl chr11:65,711,996...65,719,604 		JBrowse link
G KDM3A lysine demethylase 3A increases expression EXP quercitrin results in increased expression of KDM3A mRNA CTD PMID:25193878 NCBI chr 2:86,437,044...86,492,716
Ensembl chr 2:86,440,647...86,492,716 		JBrowse link
G KDR kinase insert domain receptor increases expression EXP quercitrin results in increased expression of KDR mRNA CTD PMID:25193878 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 increases expression EXP quercitrin results in increased expression of KEAP1 mRNA CTD PMID:25193878 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G KIR2DL3 killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 affects expression EXP quercitrin affects the expression of KIR2DL3 mRNA CTD PMID:25193878 NCBI chr19:54,738,513...54,753,052
Ensembl chr19:54,738,513...54,753,052 		JBrowse link
G KIR2DL4 killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 affects expression EXP quercitrin affects the expression of KIR2DL4 mRNA CTD PMID:25193878 NCBI chr19:54,803,610...54,814,517
Ensembl chr19:54,803,610...54,814,517 		JBrowse link
G KIR2DS5 killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 5 affects expression EXP quercitrin affects the expression of KIR2DS5 mRNA CTD PMID:25193878
G KIR3DL3 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3 affects expression EXP quercitrin affects the expression of KIR3DL3 mRNA CTD PMID:25193878 NCBI chr19:54,724,442...54,736,632
Ensembl chr19:54,724,442...54,736,632 		JBrowse link
G KLHL28 kelch like family member 28 increases expression EXP quercitrin results in increased expression of KLHL28 mRNA CTD PMID:25193878 NCBI chr14:44,924,324...44,961,947
Ensembl chr14:44,924,324...45,042,322 		JBrowse link
G KRT81 keratin 81 decreases expression EXP quercitrin results in decreased expression of KRT81 mRNA CTD PMID:25193878 NCBI chr12:52,285,913...52,308,624
Ensembl chr12:52,285,913...52,291,534 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 affects expression EXP quercitrin affects the expression of LEF1 mRNA CTD PMID:25193878 NCBI chr 4:108,047,548...108,168,932
Ensembl chr 4:108,047,545...108,168,956 		JBrowse link
G LINC01558 long intergenic non-protein coding RNA 1558 increases expression EXP quercitrin results in increased expression of LINC01558 mRNA CTD PMID:25193878 NCBI chr 6:167,784,537...167,796,859
Ensembl chr 6:167,784,537...167,796,872 		JBrowse link
G LPAR3 lysophosphatidic acid receptor 3 increases expression EXP quercitrin results in increased expression of LPAR3 mRNA CTD PMID:25193878 NCBI chr 1:84,811,602...84,893,206
Ensembl chr 1:84,811,602...84,893,206 		JBrowse link
G LPAR5 lysophosphatidic acid receptor 5 increases expression EXP quercitrin results in increased expression of LPAR5 mRNA CTD PMID:25193878 NCBI chr12:6,618,835...6,635,959
Ensembl chr12:6,618,835...6,635,960 		JBrowse link
G LPAR6 lysophosphatidic acid receptor 6 decreases expression EXP quercitrin results in decreased expression of LPAR6 mRNA CTD PMID:25193878 NCBI chr13:48,389,571...48,444,669
Ensembl chr13:48,389,567...48,444,704 		JBrowse link
G MAT2A methionine adenosyltransferase 2A increases expression EXP quercitrin results in increased expression of MAT2A mRNA CTD PMID:25193878 NCBI chr 2:85,539,168...85,545,281
Ensembl chr 2:85,539,168...85,545,281 		JBrowse link
G MC1R melanocortin 1 receptor increases expression EXP quercitrin results in increased expression of MC1R mRNA CTD PMID:25193878 NCBI chr16:89,918,862...89,920,972
Ensembl chr16:89,912,119...89,920,973 		JBrowse link
G MCTS1 MCTS1 re-initiation and release factor decreases expression EXP quercitrin results in decreased expression of MCTS1 mRNA CTD PMID:25193878 NCBI chr  X:120,604,101...120,621,159
Ensembl chr  X:120,594,010...120,621,159 		JBrowse link
G MRPL12 mitochondrial ribosomal protein L12 decreases expression EXP quercitrin results in decreased expression of MRPL12 mRNA CTD PMID:25193878 NCBI chr17:81,703,367...81,707,517
Ensembl chr17:81,703,367...81,707,517 		JBrowse link
G MRPL22 mitochondrial ribosomal protein L22 decreases expression EXP quercitrin results in decreased expression of MRPL22 mRNA CTD PMID:25193878 NCBI chr 5:154,941,073...154,969,411
Ensembl chr 5:154,941,073...154,969,411 		JBrowse link
G MSN moesin affects expression EXP quercitrin affects the expression of MSN mRNA CTD PMID:25193878 NCBI chr  X:65,588,377...65,741,931
Ensembl chr  X:65,588,377...65,741,931 		JBrowse link
G MYL2 myosin light chain 2 affects expression EXP quercitrin affects the expression of MYL2 mRNA CTD PMID:25193878 NCBI chr12:110,910,845...110,921,449
Ensembl chr12:110,910,819...110,921,443 		JBrowse link
G MYL9 myosin light chain 9 affects expression EXP quercitrin affects the expression of MYL9 mRNA CTD PMID:25193878 NCBI chr20:36,541,519...36,551,447
Ensembl chr20:36,541,497...36,551,447 		JBrowse link
G MYOM2 myomesin 2 increases expression EXP quercitrin results in increased expression of MYOM2 mRNA CTD PMID:25193878 NCBI chr 8:2,045,046...2,145,456
Ensembl chr 8:2,045,046...2,165,552 		JBrowse link
G NAA38 N-alpha-acetyltransferase 38, NatC auxiliary subunit decreases expression EXP quercitrin results in decreased expression of LSMD1 mRNA CTD PMID:25193878 NCBI chr17:7,856,685...7,885,420
Ensembl chr17:7,856,685...7,885,238 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein] CTD PMID:23138875 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NFRKB nuclear factor related to kappaB binding protein increases expression EXP quercitrin results in increased expression of NFRKB mRNA CTD PMID:25193878 NCBI chr11:129,863,636...129,895,578
Ensembl chr11:129,863,636...129,895,590 		JBrowse link
G NMUR1 neuromedin U receptor 1 decreases expression EXP quercitrin results in decreased expression of NMUR1 mRNA CTD PMID:25193878 NCBI chr 2:231,518,455...231,530,445
Ensembl chr 2:231,523,187...231,530,445 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:23138875 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NPBWR1 neuropeptides B and W receptor 1 increases expression EXP quercitrin results in increased expression of NPBWR1 mRNA CTD PMID:25193878 NCBI chr 8:52,939,182...52,943,734
Ensembl chr 8:52,939,182...52,943,734 		JBrowse link
G NPFFR2 neuropeptide FF receptor 2 decreases expression EXP quercitrin results in decreased expression of NPFFR2 mRNA CTD PMID:25193878 NCBI chr 4:72,032,000...72,148,305
Ensembl chr 4:72,031,902...72,148,305 		JBrowse link
G NPY5R neuropeptide Y receptor Y5 increases expression EXP quercitrin results in increased expression of NPY5R mRNA CTD PMID:25193878 NCBI chr 4:163,343,892...163,352,403
Ensembl chr 4:163,343,892...163,351,934 		JBrowse link
G NUAK2 NUAK family kinase 2 decreases expression EXP quercitrin results in decreased expression of NUAK2 mRNA CTD PMID:25193878 NCBI chr 1:205,302,063...205,321,745
Ensembl chr 1:205,302,063...205,321,745 		JBrowse link
G OCLN occludin affects expression EXP quercitrin affects the expression of OCLN mRNA CTD PMID:25193878 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104 		JBrowse link
G ODC1 ornithine decarboxylase 1 increases expression EXP quercitrin results in increased expression of ODC1 mRNA CTD PMID:25193878 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327 		JBrowse link
G OGA O-GlcNAcase increases expression EXP quercitrin results in increased expression of OGA mRNA CTD PMID:25193878 NCBI chr10:101,784,450...101,818,444
Ensembl chr10:101,784,443...101,818,465 		JBrowse link
G OGFOD2 2-oxoglutarate and iron dependent oxygenase domain containing 2 increases expression EXP quercitrin results in increased expression of OGFOD2 mRNA CTD PMID:25193878 NCBI chr12:122,974,726...122,980,042
Ensembl chr12:122,974,580...122,980,043 		JBrowse link
G OMA1 OMA1 zinc metallopeptidase increases expression EXP quercitrin results in increased expression of OMA1 mRNA CTD PMID:25193878 NCBI chr 1:58,480,719...58,546,726
Ensembl chr 1:58,415,384...58,546,802 		JBrowse link
G P2RX2 purinergic receptor P2X 2 increases expression EXP quercitrin results in increased expression of P2RX2 mRNA CTD PMID:25193878 NCBI chr12:132,618,776...132,622,388
Ensembl chr12:132,618,776...132,622,388 		JBrowse link
G P2RX3 purinergic receptor P2X 3 increases expression EXP quercitrin results in increased expression of P2RX3 mRNA CTD PMID:25193878 NCBI chr11:57,335,950...57,372,396
Ensembl chr11:57,338,352...57,372,396 		JBrowse link
G P2RY11 purinergic receptor P2Y11 increases expression EXP quercitrin results in increased expression of P2RY11 mRNA CTD PMID:25193878 NCBI chr19:10,111,693...10,115,372
Ensembl chr19:10,111,693...10,115,372 		JBrowse link
G P2RY6 pyrimidinergic receptor P2Y6 decreases expression EXP quercitrin results in decreased expression of P2RY6 mRNA CTD PMID:25193878 NCBI chr11:73,264,506...73,298,625
Ensembl chr11:73,264,498...73,305,103 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions ISO quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased cleavage of PARP1 protein] CTD PMID:23138875 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PATZ1 POZ/BTB and AT hook containing zinc finger 1 decreases expression EXP quercitrin results in decreased expression of PATZ1 mRNA CTD PMID:25193878 NCBI chr22:31,325,804...31,346,346
Ensembl chr22:31,325,804...31,346,346 		JBrowse link
G PEX16 peroxisomal biogenesis factor 16 decreases expression EXP quercitrin results in decreased expression of PEX16 mRNA CTD PMID:25193878 NCBI chr11:45,909,663...45,918,822
Ensembl chr11:45,909,663...45,918,812 		JBrowse link
G PGA3 pepsinogen A3 increases expression EXP quercitrin results in increased expression of PGA3 mRNA CTD PMID:25193878 NCBI chr11:61,203,515...61,213,098
Ensembl chr11:61,203,307...61,213,098 		JBrowse link
G PIDD1 p53-induced death domain protein 1 increases expression EXP quercitrin results in increased expression of PIDD1 mRNA CTD PMID:25193878 NCBI chr11:799,184...809,501
Ensembl chr11:799,179...809,753 		JBrowse link
G PIK3C2A phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha affects expression EXP quercitrin affects the expression of PIK3C2A mRNA CTD PMID:25193878 NCBI chr11:17,086,575...17,207,986
Ensembl chr11:17,077,730...17,207,986 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 affects expression EXP quercitrin affects the expression of PIK3R1 mRNA CTD PMID:25193878 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
G PLCB2 phospholipase C beta 2 affects expression EXP quercitrin affects the expression of PLCB2 mRNA CTD PMID:25193878 NCBI chr15:40,284,256...40,307,935
Ensembl chr15:40,278,176...40,307,935 		JBrowse link
G PLCE1 phospholipase C epsilon 1 affects expression EXP quercitrin affects the expression of PLCE1 mRNA CTD PMID:25193878 NCBI chr10:93,993,931...94,332,823
Ensembl chr10:93,993,931...94,332,823 		JBrowse link
G PLGRKT plasminogen receptor with a C-terminal lysine decreases expression EXP quercitrin results in decreased expression of PLGRKT mRNA CTD PMID:25193878 NCBI chr 9:5,357,971...5,438,377
Ensembl chr 9:5,357,971...5,437,925 		JBrowse link
G POC1A POC1 centriolar protein A decreases expression EXP quercitrin results in decreased expression of POC1A mRNA CTD PMID:25193878 NCBI chr 3:52,075,226...52,154,423
Ensembl chr 3:52,075,226...52,154,690 		JBrowse link
G POLH DNA polymerase eta increases expression EXP quercitrin results in increased expression of POLH mRNA CTD PMID:25193878 NCBI chr 6:43,576,185...43,620,523
Ensembl chr 6:43,576,185...43,620,523 		JBrowse link
G POLRMT RNA polymerase mitochondrial decreases expression EXP quercitrin results in decreased expression of POLRMT mRNA CTD PMID:25193878 NCBI chr19:617,221...633,537
Ensembl chr19:617,221...633,537 		JBrowse link
G POMT2 protein O-mannosyltransferase 2 increases expression EXP quercitrin results in increased expression of POMT2 mRNA CTD PMID:25193878 NCBI chr14:77,274,956...77,320,883
Ensembl chr14:77,274,956...77,320,883 		JBrowse link
G POU5F2 POU domain class 5, transcription factor 2 decreases expression EXP quercitrin results in decreased expression of POU5F2 mRNA CTD PMID:25193878 NCBI chr 5:93,733,220...93,741,600
Ensembl chr 5:93,733,220...93,741,600 		JBrowse link
G PRKCB protein kinase C beta affects expression EXP quercitrin affects the expression of PRKCB mRNA CTD PMID:25193878 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611 		JBrowse link
G PRR3 proline rich 3 decreases expression EXP quercitrin results in decreased expression of PRR3 mRNA CTD PMID:25193878 NCBI chr 6:30,556,709...30,563,723
Ensembl chr 6:30,557,280...30,563,723 		JBrowse link
G PSD4 pleckstrin and Sec7 domain containing 4 increases expression EXP quercitrin results in increased expression of PSD4 mRNA CTD PMID:25193878 NCBI chr 2:113,173,971...113,209,391
Ensembl chr 2:113,157,325...113,209,396 		JBrowse link
G PSMA6 proteasome 20S subunit alpha 6 decreases expression EXP quercitrin results in decreased expression of PSMA6 mRNA CTD PMID:25193878 NCBI chr14:35,278,558...35,317,493
Ensembl chr14:35,278,633...35,317,493 		JBrowse link
G PSMA8 proteasome 20S subunit alpha 8 decreases expression EXP quercitrin results in decreased expression of PSMA8 mRNA CTD PMID:25193878 NCBI chr18:26,133,869...26,193,355
Ensembl chr18:26,133,852...26,193,355 		JBrowse link
G PSMB6 proteasome 20S subunit beta 6 decreases expression EXP quercitrin results in decreased expression of PSMB6 mRNA CTD PMID:25193878 NCBI chr17:4,796,164...4,798,495
Ensembl chr17:4,796,144...4,798,502 		JBrowse link
G PSMB9 proteasome 20S subunit beta 9 decreases expression EXP quercitrin results in decreased expression of PSMB9 mRNA CTD PMID:25193878 NCBI chr 6:32,854,192...32,859,851
Ensembl chr 6:32,844,136...32,859,851 		JBrowse link
G PTGDR2 prostaglandin D2 receptor 2 increases expression EXP quercitrin results in increased expression of PTGDR2 mRNA CTD PMID:25193878 NCBI chr11:60,850,933...60,855,950
Ensembl chr11:60,850,933...60,855,950 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta affects expression EXP quercitrin affects the expression of PTK2B mRNA CTD PMID:25193878 NCBI chr 8:27,310,506...27,459,391
Ensembl chr 8:27,311,482...27,459,391 		JBrowse link
G PTPRU protein tyrosine phosphatase receptor type U decreases expression EXP quercitrin results in decreased expression of PTPRU mRNA CTD PMID:25193878 NCBI chr 1:29,236,522...29,326,800
Ensembl chr 1:29,236,516...29,326,813 		JBrowse link
G RAC3 Rac family small GTPase 3 affects expression EXP quercitrin affects the expression of RAC3 mRNA CTD PMID:25193878 NCBI chr17:82,031,678...82,034,204
Ensembl chr17:82,031,678...82,034,204 		JBrowse link
G RAP1A RAP1A, member of RAS oncogene family affects expression EXP quercitrin affects the expression of RAP1A mRNA CTD PMID:25193878 NCBI chr 1:111,542,009...111,716,691
Ensembl chr 1:111,542,218...111,716,691 		JBrowse link
G RBAK RB associated KRAB zinc finger increases expression EXP quercitrin results in increased expression of RBAK mRNA CTD PMID:25193878 NCBI chr 7:5,045,860...5,069,487
Ensembl chr 7:5,045,821...5,069,487 		JBrowse link
G RBKS ribokinase decreases expression EXP quercitrin results in decreased expression of RBKS mRNA CTD PMID:25193878 NCBI chr 2:27,781,379...27,890,387
Ensembl chr 2:27,781,379...27,890,681 		JBrowse link
G RBM15B RNA binding motif protein 15B increases expression EXP quercitrin results in increased expression of RBM15B mRNA CTD PMID:25193878 NCBI chr 3:51,391,285...51,397,908
Ensembl chr 3:51,391,285...51,397,908 		JBrowse link
G RBM38 RNA binding motif protein 38 increases expression EXP quercitrin results in increased expression of RBM38 mRNA CTD PMID:25193878 NCBI chr20:57,391,396...57,409,333
Ensembl chr20:57,391,396...57,409,333 		JBrowse link
G RBM39 RNA binding motif protein 39 increases expression EXP quercitrin results in increased expression of RBM39 mRNA CTD PMID:25193878 NCBI chr20:35,701,347...35,742,260
Ensembl chr20:35,701,347...35,742,312 		JBrowse link
G RCHY1 ring finger and CHY zinc finger domain containing 1 decreases expression EXP quercitrin results in decreased expression of RCHY1 mRNA CTD PMID:25193878 NCBI chr 4:75,479,033...75,514,715
Ensembl chr 4:75,479,033...75,514,764 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of RELA protein] CTD PMID:23138875 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RIOK1 RIO kinase 1 increases expression EXP quercitrin results in increased expression of RIOK1 mRNA CTD PMID:25193878 NCBI chr 6:7,389,808...7,418,037
Ensembl chr 6:7,389,793...7,418,037 		JBrowse link
G RNF14 ring finger protein 14 decreases expression EXP quercitrin results in decreased expression of RNF14 mRNA CTD PMID:25193878 NCBI chr 5:141,949,337...141,990,292
Ensembl chr 5:141,958,328...141,990,292 		JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 affects expression EXP quercitrin affects the expression of ROCK1 mRNA CTD PMID:25193878 NCBI chr18:20,946,906...21,111,813
Ensembl chr18:20,944,612...21,111,813 		JBrowse link
G SAP18 Sin3A associated protein 18 increases expression EXP quercitrin results in increased expression of SAP18 mRNA CTD PMID:25193878 NCBI chr13:21,140,119...21,149,097
Ensembl chr13:21,140,119...21,149,097 		JBrowse link
G SAT1 spermidine/spermine N1-acetyltransferase 1 decreases expression EXP quercitrin results in decreased expression of SAT1 mRNA CTD PMID:25193878 NCBI chr  X:23,783,173...23,786,210
Ensembl chr  X:23,783,173...23,786,210 		JBrowse link
G SERTAD1 SERTA domain containing 1 increases expression EXP quercitrin results in increased expression of SERTAD1 mRNA CTD PMID:25193878 NCBI chr19:40,421,589...40,425,992
Ensembl chr19:40,421,589...40,425,992 		JBrowse link
G SF3B1 splicing factor 3b subunit 1 decreases expression EXP quercitrin results in decreased expression of SF3B1 mRNA CTD PMID:25193878 NCBI chr 2:197,389,784...197,435,093
Ensembl chr 2:197,388,515...197,435,079 		JBrowse link
G SLC16A13 solute carrier family 16 member 13 decreases expression EXP quercitrin results in decreased expression of SLC16A13 mRNA CTD PMID:25193878 NCBI chr17:7,036,015...7,040,117
Ensembl chr17:7,036,015...7,040,117 		JBrowse link
G SLC16A4 solute carrier family 16 member 4 decreases expression EXP quercitrin results in decreased expression of SLC16A4 mRNA CTD PMID:25193878 NCBI chr 1:110,362,857...110,391,026
Ensembl chr 1:110,362,851...110,391,082 		JBrowse link
G SLC22A18 solute carrier family 22 member 18 decreases expression EXP quercitrin results in decreased expression of SLC22A18 mRNA CTD PMID:25193878 NCBI chr11:2,899,691...2,925,246
Ensembl chr11:2,899,721...2,925,246 		JBrowse link
G SLC25A40 solute carrier family 25 member 40 decreases expression EXP quercitrin results in decreased expression of SLC25A40 mRNA CTD PMID:25193878 NCBI chr 7:87,833,568...87,876,360
Ensembl chr 7:87,833,568...87,876,360 		JBrowse link
G SLC39A8 solute carrier family 39 member 8 decreases expression EXP quercitrin results in decreased expression of SLC39A8 mRNA CTD PMID:25193878 NCBI chr 4:102,251,041...102,345,482
Ensembl chr 4:102,251,080...102,431,258 		JBrowse link
G SLC7A9 solute carrier family 7 member 9 increases expression EXP quercitrin results in increased expression of SLC7A9 mRNA CTD PMID:25193878 NCBI chr19:32,830,511...32,869,767
Ensembl chr19:32,830,509...32,869,767 		JBrowse link
G SLFNL1 schlafen like 1 increases expression EXP quercitrin results in increased expression of SLFNL1 mRNA CTD PMID:25193878 NCBI chr 1:41,015,597...41,021,725
Ensembl chr 1:41,015,589...41,023,237 		JBrowse link
G SMAD3 SMAD family member 3 increases expression EXP quercitrin results in increased expression of SMAD3 mRNA CTD PMID:25193878 NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173 		JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 increases expression EXP quercitrin results in increased expression of SMPD1 mRNA CTD PMID:25193878 NCBI chr11:6,390,474...6,394,996
Ensembl chr11:6,390,440...6,394,998 		JBrowse link
G SNAI2 snail family transcriptional repressor 2 affects expression EXP quercitrin affects the expression of SNAI2 mRNA CTD PMID:25193878 NCBI chr 8:48,917,598...48,921,429
Ensembl chr 8:48,917,598...48,921,740 		JBrowse link
G SORBS1 sorbin and SH3 domain containing 1 affects expression EXP quercitrin affects the expression of SORBS1 mRNA CTD PMID:25193878 NCBI chr10:95,311,773...95,561,371
Ensembl chr10:95,311,771...95,561,414 		JBrowse link
G SORL1 sortilin related receptor 1 decreases expression EXP quercitrin results in decreased expression of SORL1 mRNA CTD PMID:25193878 NCBI chr11:121,452,314...121,633,763
Ensembl chr11:121,452,314...121,633,763 		JBrowse link
G SP4 Sp4 transcription factor increases expression EXP quercitrin results in increased expression of SP4 mRNA CTD PMID:25193878 NCBI chr 7:21,428,083...21,514,822
Ensembl chr 7:21,428,043...21,514,822 		JBrowse link
G SPATA18 spermatogenesis associated 18 increases expression EXP quercitrin results in increased expression of SPATA18 mRNA CTD PMID:25193878 NCBI chr 4:52,051,304...52,097,299
Ensembl chr 4:52,051,304...52,097,299 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase affects expression EXP quercitrin affects the expression of SRC mRNA CTD PMID:25193878 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G SRD5A3 steroid 5 alpha-reductase 3 increases expression EXP quercitrin results in increased expression of SRD5A3 mRNA CTD PMID:25193878 NCBI chr 4:55,346,242...55,373,100
Ensembl chr 4:55,346,213...55,373,100 		JBrowse link
G SRRM2 serine/arginine repetitive matrix 2 increases expression EXP quercitrin results in increased expression of SRRM2 mRNA CTD PMID:25193878 NCBI chr16:2,752,638...2,771,412
Ensembl chr16:2,752,626...2,772,538 		JBrowse link
G SUGCT succinyl-CoA:glutarate-CoA transferase increases expression EXP quercitrin results in increased expression of SUGCT mRNA CTD PMID:25193878 NCBI chr 7:40,135,005...41,038,816
Ensembl chr 7:40,135,005...40,860,763 		JBrowse link
G SUGP1 SURP and G-patch domain containing 1 increases expression EXP quercitrin results in increased expression of SUGP1 mRNA CTD PMID:25193878 NCBI chr19:19,276,033...19,320,509
Ensembl chr19:19,276,018...19,320,509 		JBrowse link
G TCEA1 transcription elongation factor A1 decreases expression EXP quercitrin results in decreased expression of TCEA1 mRNA CTD PMID:25193878 NCBI chr 8:53,966,556...54,022,448
Ensembl chr 8:53,966,552...54,022,448 		JBrowse link
G TCEA2 transcription elongation factor A2 decreases expression EXP quercitrin results in decreased expression of TCEA2 mRNA CTD PMID:25193878 NCBI chr20:64,055,596...64,072,347
Ensembl chr20:64,049,836...64,072,347 		JBrowse link
G TCF7 transcription factor 7 affects expression EXP quercitrin affects the expression of TCF7 mRNA CTD PMID:25193878 NCBI chr 5:134,108,218...134,148,210
Ensembl chr 5:134,114,681...134,151,865 		JBrowse link
G TFB1M transcription factor B1, mitochondrial decreases expression EXP quercitrin results in decreased expression of TFB1M mRNA CTD PMID:25193878 NCBI chr 6:155,229,871...155,314,484
Ensembl chr 6:155,256,134...155,314,493 		JBrowse link
G TGIF2 TGFB induced factor homeobox 2 decreases expression EXP quercitrin results in decreased expression of TGIF2 mRNA CTD PMID:25193878 NCBI chr20:36,573,464...36,593,950
Ensembl chr20:36,573,488...36,593,950 		JBrowse link
G TGM2 transglutaminase 2 decreases expression EXP quercitrin results in decreased expression of TGM2 mRNA CTD PMID:25193878 NCBI chr20:38,127,385...38,168,475
Ensembl chr20:38,127,385...38,166,578 		JBrowse link
G THSD1 thrombospondin type 1 domain containing 1 increases expression EXP quercitrin results in increased expression of THSD1 mRNA CTD PMID:25193878 NCBI chr13:52,377,167...52,406,172
Ensembl chr13:52,377,167...52,416,373 		JBrowse link
G TMEM160 transmembrane protein 160 decreases expression EXP quercitrin results in decreased expression of TMEM160 mRNA CTD PMID:25193878 NCBI chr19:47,045,909...47,048,624
Ensembl chr19:47,045,909...47,048,624 		JBrowse link
G TMEM208 transmembrane protein 208 decreases expression EXP quercitrin results in decreased expression of TMEM208 mRNA CTD PMID:25193878 NCBI chr16:67,227,130...67,229,278
Ensembl chr16:67,227,103...67,229,278 		JBrowse link
G TMEM242 transmembrane protein 242 increases expression EXP quercitrin results in increased expression of TMEM242 mRNA CTD PMID:25193878 NCBI chr 6:157,289,025...157,323,519
Ensembl chr 6:157,289,025...157,323,601 		JBrowse link
G TMX1 thioredoxin related transmembrane protein 1 decreases expression EXP quercitrin results in decreased expression of TMX1 mRNA CTD PMID:25193878 NCBI chr14:51,240,247...51,257,655
Ensembl chr14:51,240,162...51,257,655 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of BAX protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of RELA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased cleavage of PARP1 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of CASP3 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:23138875 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A decreases expression EXP quercitrin results in decreased expression of TNFRSF1A mRNA CTD PMID:25193878 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B decreases expression EXP quercitrin results in decreased expression of TNFRSF1B mRNA CTD PMID:25193878 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
G TP63 tumor protein p63 decreases expression EXP quercitrin results in decreased expression of TP63 mRNA CTD PMID:25193878 NCBI chr 3:189,596,746...189,897,276
Ensembl chr 3:189,631,389...189,897,276 		JBrowse link
G TSPAN14 tetraspanin 14 decreases expression EXP quercitrin results in decreased expression of TSPAN14 mRNA CTD PMID:25193878 NCBI chr10:80,454,310...80,522,631
Ensembl chr10:80,454,265...80,533,124 		JBrowse link
G U2AF2 U2 small nuclear RNA auxiliary factor 2 increases expression EXP quercitrin results in increased expression of U2AF2 mRNA CTD PMID:25193878 NCBI chr19:55,655,035...55,674,716
Ensembl chr19:55,654,146...55,674,716 		JBrowse link
G UTS2R urotensin 2 receptor increases expression EXP quercitrin results in increased expression of UTS2R mRNA CTD PMID:25193878 NCBI chr17:82,371,765...82,377,458
Ensembl chr17:82,371,765...82,377,458 		JBrowse link
G VN1R1 vomeronasal 1 receptor 1 increases expression EXP quercitrin results in increased expression of VN1R1 mRNA CTD PMID:25193878 NCBI chr19:57,454,790...57,457,140
Ensembl chr19:57,454,790...57,457,140 		JBrowse link
G VWA8 von Willebrand factor A domain containing 8 decreases expression EXP quercitrin results in decreased expression of VWA8 mRNA CTD PMID:25193878 NCBI chr13:41,566,835...41,961,109
Ensembl chr13:41,566,835...41,961,120 		JBrowse link
G WAS WASP actin nucleation promoting factor affects expression EXP quercitrin affects the expression of WAS mRNA CTD PMID:25193878 NCBI chr  X:48,676,636...48,691,427
Ensembl chr  X:48,676,596...48,691,431 		JBrowse link
G WDR33 WD repeat domain 33 decreases expression EXP quercitrin results in decreased expression of WDR33 mRNA CTD PMID:25193878 NCBI chr 2:127,701,027...127,811,171
Ensembl chr 2:127,701,027...127,811,187 		JBrowse link
G WWOX WW domain containing oxidoreductase decreases expression EXP quercitrin results in decreased expression of WWOX mRNA CTD PMID:25193878 NCBI chr16:78,099,654...79,212,667
Ensembl chr16:78,099,400...79,212,667 		JBrowse link
G ZAN zonadhesin increases expression EXP quercitrin results in increased expression of ZAN mRNA CTD PMID:25193878 NCBI chr 7:100,733,595...100,797,797
Ensembl chr 7:100,733,595...100,797,797 		JBrowse link
G ZCCHC14 zinc finger CCHC-type containing 14 increases expression EXP quercitrin results in increased expression of ZCCHC14 mRNA CTD PMID:25193878 NCBI chr16:87,406,248...87,493,024
Ensembl chr16:87,406,246...87,493,024 		JBrowse link
G ZCCHC18 zinc finger CCHC-type containing 18 increases expression EXP quercitrin results in increased expression of ZCCHC18 mRNA CTD PMID:25193878 NCBI chr  X:104,112,523...104,115,842
Ensembl chr  X:104,112,131...104,115,842 		JBrowse link
G ZNF502 zinc finger protein 502 increases expression EXP quercitrin results in increased expression of ZNF502 mRNA CTD PMID:25193878 NCBI chr 3:44,712,660...44,723,831
Ensembl chr 3:44,712,643...44,723,831 		JBrowse link
robinin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) affects activity EXP robinin affects the activity of ABCC1 protein CTD PMID:15796199 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
rutin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 multiple interactions ISO Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of ABCA1 mRNA]; Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of ABCA1 protein] CTD PMID:25478064 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155 		JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions EXP Rutin promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]] CTD PMID:34217736 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ACHE acetylcholinesterase (Yt blood group) multiple interactions ISO Rutin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in decreased activity of ACHE protein]; Rutin inhibits the reaction [Acrylamide results in increased expression of ACHE protein] CTD PMID:32881150 PMID:36657526 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G ACLY ATP citrate lyase decreases activity ISO Rutin results in decreased activity of ACLY protein CTD PMID:17032037 NCBI chr17:41,866,917...41,930,545
Ensembl chr17:41,866,917...41,930,542 		JBrowse link
G AGER advanced glycosylation end-product specific receptor multiple interactions EXP Rutin inhibits the reaction [Glucose results in increased expression of AGER mRNA] CTD PMID:19557821 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G AGT angiotensinogen multiple interactions ISO Rutin inhibits the reaction [Isoproterenol results in increased expression of AGT protein] CTD PMID:24117263 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AHR aryl hydrocarbon receptor decreases localization
multiple interactions		 EXP Rutin results in decreased localization of AHR protein
Rutin promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased localization of AHR protein]		 CTD PMID:21756928 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions ISO Rutin inhibits the reaction [Fructose results in decreased phosphorylation of AKT1 protein]
Rutin inhibits the reaction [Cisplatin results in decreased phosphorylation of AKT1 protein]		 CTD PMID:22426011 PMID:35304134 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator increases localization EXP Rutin results in increased localization of ARNT protein CTD PMID:21756928 NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708 		JBrowse link
G ATXN2 ataxin 2 multiple interactions ISO Rutin inhibits the reaction [Oxidopamine results in increased expression of ATXN2 mRNA] CTD PMID:25129099 NCBI chr12:111,452,214...111,599,673
Ensembl chr12:111,443,485...111,599,676 		JBrowse link
G ATXN3 ataxin 3 multiple interactions ISO Rutin inhibits the reaction [Oxidopamine results in increased expression of ATXN3 mRNA] CTD PMID:25129099 NCBI chr14:92,044,775...92,106,582
Ensembl chr14:92,044,496...92,106,621 		JBrowse link
G BAD BCL2 associated agonist of cell death multiple interactions ISO Rutin inhibits the reaction [Cisplatin results in increased expression of BAD protein] CTD PMID:35304134 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator affects expression
multiple interactions
increases expression		 EXP
ISO		 Rutin affects the expression of BAX protein
Rutin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of BAX protein]; Rutin inhibits the reaction [Oxygen deficiency results in increased expression of BAX mRNA]; Rutin inhibits the reaction [Oxygen deficiency results in increased expression of BAX protein]
Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of BAX protein]
Rutin results in increased expression of BAX protein		 CTD PMID:15975156 PMID:28811126 PMID:29522708 PMID:32881150 PMID:33413359 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BBC3 BCL2 binding component 3 multiple interactions ISO Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of BBC3 mRNA] CTD PMID:27239252 NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766 		JBrowse link
G BCL2 BCL2 apoptosis regulator affects expression
multiple interactions
decreases expression		 EXP
ISO		 Rutin affects the expression of BCL2 protein
Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of BCL2 protein]
Rutin results in decreased expression of BCL2 protein
Rutin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of BCL2 protein]; Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of BCL2 mRNA]; Rutin inhibits the reaction [Oxygen deficiency results in decreased expression of BCL2 mRNA]; Rutin inhibits the reaction [Oxygen deficiency results in decreased expression of BCL2 protein]
Rutin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of BCL2 protein]		 CTD PMID:15975156 PMID:19557821 PMID:26062544 PMID:28811126 PMID:29522708 More... NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions ISO Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of BCL2L1 mRNA] CTD PMID:26062544 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein multiple interactions EXP [Rutin co-treated with Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased secretion of BGLAP protein CTD PMID:34562440 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in increased phosphorylation of BRAF protein] CTD PMID:32864822 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929 		JBrowse link
G CASP1 caspase 1 multiple interactions ISO Rutin inhibits the reaction [Fructose results in increased expression of CASP1 protein] CTD PMID:22426011 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CASP3 caspase 3 affects cleavage
increases cleavage
multiple interactions
increases expression
increases activity		 EXP
ISO		 Rutin affects the cleavage of CASP3 protein
Rutin results in increased cleavage of CASP3 protein
Rutin inhibits the reaction [Cholesterol, Dietary results in increased cleavage of CASP3 protein]; Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of CASP3 mRNA]; Rutin inhibits the reaction [Oxidopamine results in increased expression of CASP3 mRNA]; Rutin inhibits the reaction [Oxygen deficiency results in increased cleavage of CASP3 protein]; Rutin inhibits the reaction [Oxygen deficiency results in increased expression of CASP3 mRNA]
[Rutin binds to Zinc] which results in increased expression of CASP3 mRNA; [Rutin co-treated with Meloxicam] affects the reaction [Formaldehyde affects the expression of CASP3 protein]; Rutin inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP3 protein]; Rutin inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Rutin inhibits the reaction [Oxaliplatin results in increased expression of CASP3 protein]
Rutin results in increased expression of CASP3 mRNA
Rutin results in increased activity of CASP3 protein		 CTD PMID:15975156 PMID:24726691 PMID:24908156 PMID:25129099 PMID:26091902 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP7 caspase 7 increases activity
multiple interactions		 EXP
ISO		 Rutin results in increased activity of CASP7 protein
Rutin inhibits the reaction [Oxidopamine results in increased expression of CASP7 mRNA]		 CTD PMID:24726691 PMID:25129099 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907 		JBrowse link
G CASP8 caspase 8 multiple interactions
increases expression		 ISO [Rutin binds to Zinc] which results in increased expression of CASP8 mRNA
Rutin results in increased expression of CASP8 mRNA		 CTD PMID:26091902 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 multiple interactions EXP Rutin inhibits the reaction [Cisplatin results in decreased expression of CASP9 protein] CTD PMID:29962303 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase multiple interactions EXP
ISO		 Rutin inhibits the reaction [bifenthrin results in decreased activity of CAT protein]
Rutin inhibits the reaction [Lipopolysaccharides results in decreased activity of CAT protein]
Rutin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in decreased activity of CAT protein]; Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CAT mRNA]; Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CAT protein]; Rutin inhibits the reaction [Cisplatin results in decreased expression of CAT protein]; Rutin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; Rutin inhibits the reaction [Oxygen deficiency results in decreased activity of CAT protein]		 CTD PMID:19833193 PMID:21605616 PMID:25478064 PMID:25753322 PMID:29743444 More... NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CBR1 carbonyl reductase 1 multiple interactions EXP Rutin binds to and results in decreased activity of CBR1 protein; Rutin inhibits the reaction [CBR1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] CTD PMID:11306090 PMID:18579125 NCBI chr21:36,070,024...36,073,164
Ensembl chr21:36,069,941...36,073,166 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions
decreases secretion
decreases expression		 EXP
ISO		 Rutin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 mRNA]
Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 protein]
Rutin results in decreased secretion of CCL2 protein
Rutin results in decreased expression of CCL2 mRNA		 CTD PMID:21756928 PMID:21967610 PMID:25478064 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions
decreases expression		 ISO Lipopolysaccharides inhibits the reaction [Rutin results in decreased expression of CCL5 mRNA] CTD PMID:28693884 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCN2 cellular communication network factor 2 multiple interactions ISO Rutin inhibits the reaction [Isoproterenol results in increased expression of CCN2 mRNA]; Rutin inhibits the reaction [Isoproterenol results in increased expression of CCN2 protein] CTD PMID:24117263 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372 		JBrowse link
G CCND1 cyclin D1 multiple interactions
decreases expression		 ISO [Rutin binds to Zinc] which results in decreased expression of CCND1 mRNA
Rutin results in decreased expression of CCND1 mRNA		 CTD PMID:26091902 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CD68 CD68 molecule decreases expression ISO Rutin results in decreased expression of CD68 protein CTD PMID:28693884 NCBI chr17:7,579,638...7,582,111
Ensembl chr17:7,579,491...7,582,111 		JBrowse link
G CHAT choline O-acetyltransferase multiple interactions ISO Rutin inhibits the reaction [Acrylamide results in decreased expression of CHAT protein] CTD PMID:36657526 NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,667,942 		JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions EXP [Rutin co-treated with Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of COL1A1 mRNA CTD PMID:34562440 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G CSF2 colony stimulating factor 2 multiple interactions ISO Rutin inhibits the reaction [Dextran Sulfate results in increased expression of CSF2 mRNA] CTD PMID:15652231 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 decreases expression ISO Rutin results in decreased expression of CX3CL1 mRNA CTD PMID:28693884 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 multiple interactions
decreases secretion
decreases expression		 EXP Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]
Rutin results in decreased secretion of CXCL10 protein
Rutin results in decreased expression of CXCL10 mRNA		 CTD PMID:21756928 PMID:21967610 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 multiple interactions
decreases expression		 ISO Lipopolysaccharides inhibits the reaction [Rutin results in decreased expression of CXCL12 mRNA] CTD PMID:28693884 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions
decreases secretion		 EXP Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CXCL8 mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of CXCL8 protein]; Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein]; Rutin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CXCL8 mRNA]
Rutin results in decreased secretion of CXCL8 protein		 CTD PMID:18958421 PMID:21756928 PMID:21967610 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYCS cytochrome c, somatic multiple interactions ISO Rutin inhibits the reaction [Oxygen deficiency results in increased expression of CYCS mRNA]; Rutin inhibits the reaction [Oxygen deficiency results in increased expression of CYCS protein] CTD PMID:33413359 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 increases expression ISO Rutin results in increased expression of CYP19A1 protein CTD PMID:29899696 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases expression EXP Rutin results in increased expression of CYP1A1 mRNA CTD PMID:21756928 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 decreases activity EXP Rutin results in decreased activity of CYP1B1 protein CTD PMID:16271822 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G EGF epidermal growth factor multiple interactions ISO Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of EGF mRNA] CTD PMID:26062544 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGFR epidermal growth factor receptor multiple interactions EXP Rutin inhibits the reaction [TGFA protein affects the localization of EGFR protein] CTD PMID:21967610 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 multiple interactions ISO Rutin inhibits the reaction [Oxidopamine results in increased expression of EGLN1 mRNA] CTD PMID:25129099 NCBI chr 1:231,363,756...231,422,287
Ensembl chr 1:231,363,751...231,422,287 		JBrowse link
G ESR2 estrogen receptor 2 increases expression ISO Rutin results in increased expression of ESR2 protein CTD PMID:29899696 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G FADD Fas associated via death domain multiple interactions ISO Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of FADD mRNA] CTD PMID:26062544 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390 		JBrowse link
G FN1 fibronectin 1 increases expression
multiple interactions		 EXP
ISO		 Rutin results in increased expression of FN1 protein
Rutin inhibits the reaction [Isoproterenol results in increased expression of FN1 protein]		 CTD PMID:24117263 PMID:26408079 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Rutin inhibits the reaction [oxaliplatin results in increased expression of FOS protein] CTD PMID:24908156 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G FOXO3 forkhead box O3 multiple interactions ISO Rutin inhibits the reaction [Cisplatin affects the localization of FOXO3 protein] CTD PMID:33031932 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774 		JBrowse link
G FSHR follicle stimulating hormone receptor increases expression ISO Rutin results in increased expression of FSHR protein CTD PMID:29899696 NCBI chr 2:48,962,157...49,154,515
Ensembl chr 2:48,962,157...49,154,527 		JBrowse link
G GDNF glial cell derived neurotrophic factor increases expression ISO Rutin results in increased expression of GDNF mRNA CTD PMID:28693884 NCBI chr 5:37,812,677...37,840,041
Ensembl chr 5:37,812,677...37,840,041 		JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of GPT protein]; Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of GPT protein]; Rutin inhibits the reaction [Cyclophosphamide results in increased activity of GPT protein] CTD PMID:25478064 PMID:25753322 PMID:26062544 PMID:27239252 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions ISO Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of GPX1 mRNA]; Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of GPX1 protein] CTD PMID:25478064 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GSR glutathione-disulfide reductase decreases activity
multiple interactions		 EXP
ISO		 Rutin results in decreased activity of GSR protein
Rutin inhibits the reaction [Cisplatin results in decreased expression of GSR protein]; Rutin inhibits the reaction [Cyclophosphamide results in decreased activity of GSR protein]		 CTD PMID:15782287 PMID:21605616 PMID:25753322 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions ISO Rutin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]; Rutin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein] CTD PMID:33413359 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO [Rutin co-treated with Carbon Tetrachloride] results in increased expression of HMOX1 protein CTD PMID:22902988 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G IFNG interferon gamma multiple interactions EXP Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein] CTD PMID:21756928 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IGF1 insulin like growth factor 1 multiple interactions ISO [Lipopolysaccharides co-treated with Rutin] results in decreased expression of IGF1 mRNA CTD PMID:28693884 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IGF1R insulin like growth factor 1 receptor multiple interactions EXP Rutin results in increased susceptibility to [Vitamin E results in decreased expression of IGF1R protein] CTD PMID:20015448 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G IL10 interleukin 10 multiple interactions
increases expression		 ISO Lipopolysaccharides promotes the reaction [Rutin results in increased expression of IL10 mRNA]
Rutin results in increased expression of IL10 mRNA; Rutin results in increased expression of IL10 protein		 CTD PMID:28693884 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL18 interleukin 18 multiple interactions
decreases expression		 ISO Rutin inhibits the reaction [Fructose results in increased expression of IL18 protein]
Rutin results in decreased expression of IL18 mRNA		 CTD PMID:22426011 PMID:28693884 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1B interleukin 1 beta multiple interactions
decreases expression		 EXP
ISO		 Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL1B protein]; Rutin inhibits the reaction [Glucose results in increased expression of IL1B mRNA]; Rutin inhibits the reaction [Glucose results in increased expression of IL1B protein]
Rutin results in decreased expression of IL1B mRNA
Lipopolysaccharides inhibits the reaction [Rutin results in decreased expression of IL1B mRNA]; Rutin inhibits the reaction [Fructose results in increased expression of IL1B protein]
[Rutin co-treated with Meloxicam] affects the reaction [Formaldehyde affects the expression of IL1B protein]; Rutin affects the reaction [Formaldehyde affects the expression of IL1B protein]; Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B protein]; Rutin inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; Rutin inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]		 CTD PMID:15652231 PMID:18958421 PMID:19557821 PMID:22426011 PMID:28693884 More... NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions
decreases expression		 EXP
ISO		 Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; Rutin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]
Rutin results in decreased expression of IL6 mRNA; Rutin results in decreased expression of IL6 protein
Lipopolysaccharides inhibits the reaction [Rutin results in decreased expression of IL6 mRNA]; Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 mRNA]; Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of IL6 mRNA]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Rutin inhibits the reaction [Fructose results in increased expression of IL6 protein]
Rutin inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; Rutin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Rutin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]		 CTD PMID:15652231 PMID:18958421 PMID:21756928 PMID:22426011 PMID:25753322 More... NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO Rutin inhibits the reaction [Fructose results in increased expression of INS1 protein] CTD PMID:19605544 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G INSR insulin receptor multiple interactions ISO Rutin inhibits the reaction [Fructose results in decreased phosphorylation of INSR protein] CTD PMID:22426011 NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414 		JBrowse link
G IRS1 insulin receptor substrate 1 decreases expression
multiple interactions		 EXP
ISO		 Rutin results in decreased expression of IRS1 protein
Rutin inhibits the reaction [Fructose results in decreased phosphorylation of IRS1 protein]
Rutin results in increased susceptibility to [Vitamin E results in decreased expression of IRS1 protein]; Vitamin E results in increased susceptibility to [Rutin results in decreased expression of IRS1 protein]		 CTD PMID:20015448 PMID:22426011 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820 		JBrowse link
G ITGAM integrin subunit alpha M multiple interactions
increases expression		 ISO Lipopolysaccharides inhibits the reaction [Rutin results in increased expression of ITGAM protein] CTD PMID:28693884 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
G JAK1 Janus kinase 1 multiple interactions ISO Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of JAK1 mRNA] CTD PMID:26062544 NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754 		JBrowse link
G JAK2 Janus kinase 2 multiple interactions ISO Rutin inhibits the reaction [Fructose results in decreased phosphorylation of JAK2 protein] CTD PMID:22426011 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions		 EXP Rutin results in decreased expression of JUN protein
Rutin results in increased susceptibility to [Vitamin E results in decreased expression of JUN protein]; Vitamin E results in increased susceptibility to [Rutin results in decreased expression of JUN protein]		 CTD PMID:20015448 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G LAMB2 laminin subunit beta 2 increases expression EXP Rutin results in increased expression of LAMB2 protein CTD PMID:26408079 NCBI chr 3:49,121,114...49,133,050
Ensembl chr 3:49,121,114...49,133,118 		JBrowse link
G LEP leptin multiple interactions ISO Rutin inhibits the reaction [Fructose results in increased expression of LEP protein] CTD PMID:22426011 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LEPR leptin receptor multiple interactions ISO Rutin inhibits the reaction [Fructose results in increased expression of and results in increased phosphorylation of LEPR protein] CTD PMID:22426011 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559 		JBrowse link
G LGALS9 galectin 9 multiple interactions ISO Rutin inhibits the reaction [Fructose results in decreased expression of LGALS9 mRNA]; Rutin inhibits the reaction [Fructose results in decreased expression of LGALS9 protein] CTD PMID:19605544 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
G MAP2K5 mitogen-activated protein kinase kinase 5 multiple interactions ISO Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of MAP2K5 mRNA] CTD PMID:26062544 NCBI chr15:67,542,703...67,807,114
Ensembl chr15:67,542,703...67,807,117 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
decreases phosphorylation		 EXP
ISO		 Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; Rutin inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]
Rutin inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK1 protein]
Rutin inhibits the reaction [Acrylamide results in decreased phosphorylation of MAPK1 protein]; Rutin inhibits the reaction [Fructose results in decreased phosphorylation of MAPK1 protein]; Rutin inhibits the reaction [pirarubicin results in increased phosphorylation of MAPK1 protein]
Rutin results in decreased phosphorylation of MAPK1 protein		 CTD PMID:19557821 PMID:21756928 PMID:22426011 PMID:29522708 PMID:32864822 More... NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 multiple interactions ISO Rutin inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK14 protein] CTD PMID:35304134 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
decreases phosphorylation		 EXP
ISO		 Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; Rutin inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]
Rutin inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK3 protein]
Rutin inhibits the reaction [Acrylamide results in decreased phosphorylation of MAPK3 protein]; Rutin inhibits the reaction [Fructose results in decreased phosphorylation of MAPK3 protein]; Rutin inhibits the reaction [pirarubicin results in increased phosphorylation of MAPK3 protein]
Rutin results in decreased phosphorylation of MAPK3 protein		 CTD PMID:19557821 PMID:21756928 PMID:22426011 PMID:29522708 PMID:32864822 More... NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions ISO Rutin inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK8 protein] CTD PMID:35304134 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MIR100 microRNA 100 multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in decreased expression of MIR100 mRNA] CTD PMID:32864822 NCBI chr11:122,152,229...122,152,308
Ensembl chr11:122,152,229...122,152,308 		JBrowse link
G MIR125B1 microRNA 125b-1 multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in increased expression of MIR125B1 mRNA] CTD PMID:32864822 NCBI chr11:122,099,757...122,099,844
Ensembl chr11:122,099,757...122,099,844 		JBrowse link
G MIR1306 microRNA 1306 multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in increased expression of MIR1306 mRNA] CTD PMID:32864822 NCBI chr22:20,086,058...20,086,142
Ensembl chr22:20,086,058...20,086,142 		JBrowse link
G MIR152 microRNA 152 multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in decreased expression of MIR152 mRNA] CTD PMID:32864822 NCBI chr17:48,037,161...48,037,247
Ensembl chr17:48,037,161...48,037,247 		JBrowse link
G MIR181C microRNA 181c multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in decreased expression of MIR181C mRNA] CTD PMID:32864822 NCBI chr19:13,874,699...13,874,808
Ensembl chr19:13,874,699...13,874,808 		JBrowse link
G MIR185 microRNA 185 multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in increased expression of MIR185 mRNA] CTD PMID:32864822 NCBI chr22:20,033,139...20,033,220
Ensembl chr22:20,033,139...20,033,220 		JBrowse link
G MIR195 microRNA 195 multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in decreased expression of MIR195 mRNA] CTD PMID:32864822 NCBI chr17:7,017,615...7,017,701
Ensembl chr17:7,017,615...7,017,701 		JBrowse link
G MIR196A1 microRNA 196a-1 multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in increased expression of MIR196C mRNA] CTD PMID:32864822 NCBI chr17:48,632,490...48,632,559
Ensembl chr17:48,632,490...48,632,559 		JBrowse link
G MIR199A2 microRNA 199a-2 multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in decreased expression of MIR199A2 mRNA] CTD PMID:32864822 NCBI chr 1:172,144,535...172,144,644
Ensembl chr 1:172,144,535...172,144,644 		JBrowse link
G MIR204 microRNA 204 multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in increased expression of MIR204 mRNA] CTD PMID:32864822 NCBI chr 9:70,809,975...70,810,084
Ensembl chr 9:70,809,975...70,810,084 		JBrowse link
G MIR208B microRNA 208b multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in decreased expression of MIR208B mRNA] CTD PMID:32864822 NCBI chr14:23,417,987...23,418,063
Ensembl chr14:23,417,987...23,418,063 		JBrowse link
G MIR211 microRNA 211 multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in increased expression of MIR211 mRNA] CTD PMID:32864822 NCBI chr15:31,065,032...31,065,141
Ensembl chr15:31,065,032...31,065,141 		JBrowse link
G MIR22 microRNA 22 multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in decreased expression of MIR22 mRNA] CTD PMID:32864822 NCBI chr17:1,713,903...1,713,987
Ensembl chr17:1,713,903...1,713,987 		JBrowse link
G MIR26B microRNA 26b multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in decreased expression of MIR26B mRNA] CTD PMID:32864822 NCBI chr 2:218,402,646...218,402,722
Ensembl chr 2:218,402,646...218,402,722 		JBrowse link
G MIR296 microRNA 296 multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in increased expression of MIR296 mRNA] CTD PMID:32864822 NCBI chr20:58,817,615...58,817,694
Ensembl chr20:58,817,615...58,817,694 		JBrowse link
G MIR30C1 microRNA 30c-1 multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in increased expression of MIR30C1 mRNA] CTD PMID:32864822 NCBI chr 1:40,757,284...40,757,372
Ensembl chr 1:40,757,284...40,757,372 		JBrowse link
G MIR365B microRNA 365b multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in increased expression of MIR365B mRNA] CTD PMID:32864822 NCBI chr17:31,575,411...31,575,521
Ensembl chr17:31,575,411...31,575,521 		JBrowse link
G MIR494 microRNA 494 multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in increased expression of MIR494 mRNA] CTD PMID:32864822 NCBI chr14:101,029,634...101,029,714
Ensembl chr14:101,029,634...101,029,714 		JBrowse link
G MIR760 microRNA 760 multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in increased expression of MIR760 mRNA] CTD PMID:32864822 NCBI chr 1:93,846,832...93,846,911
Ensembl chr 1:93,846,832...93,846,911 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions EXP
ISO		 Rutin results in decreased expression of and results in decreased activity of MMP2 protein
Rutin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP2 mRNA]; Rutin inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP2 protein]		 CTD PMID:26408079 PMID:29743444 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 decreases expression
multiple interactions		 ISO Rutin results in decreased expression of MMP9 mRNA
Rutin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA]; Rutin inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP9 protein]		 CTD PMID:16304905 PMID:29743444 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MPO myeloperoxidase multiple interactions ISO Rutin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased activity of MPO protein] CTD PMID:32881150 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MRC1 mannose receptor C-type 1 increases expression
multiple interactions		 ISO Rutin results in increased expression of MRC1 protein
[Lipopolysaccharides co-treated with Rutin] results in increased expression of MRC1 protein		 CTD PMID:28693884 NCBI chr10:17,809,348...17,911,164
Ensembl chr10:17,809,348...17,911,164 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions ISO Rutin promotes the reaction [Carbon Tetrachloride results in increased expression of NFE2L2 protein]
[Rutin co-treated with Hydrogen Peroxide] affects the localization of NFE2L2 protein; Rutin inhibits the reaction [Acrylamide results in decreased expression of NFE2L2 protein]		 CTD PMID:22902988 PMID:31412289 PMID:36657526 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions EXP Rutin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of NFKBIA protein] CTD PMID:19557821 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 multiple interactions ISO Rutin inhibits the reaction [Fructose results in increased expression of NLRP3 protein] CTD PMID:22426011 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
decreases expression		 ISO Rutin inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein]; Rutin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein]; Rutin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
Rutin results in decreased expression of NOS2 mRNA; Rutin results in decreased expression of NOS2 protein
Rutin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of NOS2 protein]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]		 CTD PMID:11500931 PMID:12512693 PMID:22902988 PMID:25080890 PMID:25753322 More... NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NSF N-ethylmaleimide sensitive factor, vesicle fusing ATPase multiple interactions ISO Rutin inhibits the reaction [Oxidopamine results in decreased expression of NSF mRNA] CTD PMID:25129099 NCBI chr17:46,590,669...46,757,464
Ensembl chr17:46,590,669...46,757,679 		JBrowse link
G NSG1 neuronal vesicle trafficking associated 1 multiple interactions ISO Rutin inhibits the reaction [Oxidopamine results in decreased expression of NSG1 mRNA] CTD PMID:25129099 NCBI chr 4:4,386,532...4,419,058
Ensembl chr 4:4,348,140...4,419,058 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase multiple interactions ISO Rutin inhibits the reaction [Oxidopamine results in decreased expression of OPA1 mRNA] CTD PMID:25129099 NCBI chr 3:193,593,208...193,697,811
Ensembl chr 3:193,593,144...193,697,811 		JBrowse link
G PARK7 Parkinsonism associated deglycase multiple interactions ISO Rutin inhibits the reaction [Oxidopamine results in increased expression of PARK7 mRNA] CTD PMID:25129099 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PNPLA3 patatin like phospholipase domain containing 3 decreases expression ISO Rutin results in decreased expression of PNPLA3 mRNA CTD PMID:17032037 NCBI chr22:43,923,805...43,947,582
Ensembl chr22:43,923,792...43,964,488 		JBrowse link
G PON1 paraoxonase 1 multiple interactions
increases expression		 ISO Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PON1 mRNA]; Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PON1 protein]
Rutin results in increased expression of PON1 mRNA		 CTD PMID:25478064 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532 		JBrowse link
G PON3 paraoxonase 3 multiple interactions ISO Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PON3 mRNA]; Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PON3 protein] CTD PMID:25478064 NCBI chr 7:95,359,872...95,396,375
Ensembl chr 7:95,359,872...95,396,375 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions ISO Rutin inhibits the reaction [Fructose results in decreased expression of PPARA protein] CTD PMID:22426011 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARD peroxisome proliferator activated receptor delta multiple interactions ISO Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PPARD mRNA]; Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PPARD protein] CTD PMID:25478064 NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191 		JBrowse link
G PPID peptidylprolyl isomerase D multiple interactions ISO Rutin inhibits the reaction [Oxidopamine results in increased expression of PPID mRNA] CTD PMID:25129099 NCBI chr 4:158,709,127...158,723,396
Ensembl chr 4:158,709,127...158,723,396 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase multiple interactions ISO Rutin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] CTD PMID:25129099 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G PTEN phosphatase and tensin homolog multiple interactions ISO Rutin inhibits the reaction [Cisplatin results in increased phosphorylation of PTEN protein] CTD PMID:33031932 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression		 EXP
ISO		 [Rutin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of PTGS2 mRNA; Rutin inhibits the reaction [Glucose results in increased expression of PTGS2 mRNA]; Rutin inhibits the reaction [Glucose results in increased expression of PTGS2 protein]
Rutin results in decreased expression of PTGS2 mRNA
Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein]; Rutin inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]; Rutin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein]; Rutin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
Rutin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of PTGS2 protein]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]		 CTD PMID:11500931 PMID:15652231 PMID:19557821 PMID:21756928 PMID:22902988 More... NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PYCARD PYD and CARD domain containing multiple interactions ISO Rutin inhibits the reaction [Fructose results in increased expression of PYCARD protein] CTD PMID:22426011 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G RAP1A RAP1A, member of RAS oncogene family multiple interactions ISO Rutin inhibits the reaction [pirarubicin results in increased expression of RAP1A mRNA]; Rutin inhibits the reaction [pirarubicin results in increased expression of RAP1A protein] CTD PMID:32864822 NCBI chr 1:111,542,009...111,716,691
Ensembl chr 1:111,542,218...111,716,691 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP
ISO		 Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; Rutin inhibits the reaction [Glucose affects the localization of RELA protein]; Rutin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of RELA protein]
Rutin inhibits the reaction [Carbon Tetrachloride affects the localization of RELA protein]		 CTD PMID:19557821 PMID:21756928 PMID:29522708 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RUNX2 RUNX family transcription factor 2 multiple interactions EXP [Rutin co-treated with Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA CTD PMID:34562440 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349 		JBrowse link
G SIRT1 sirtuin 1 increases expression ISO Rutin results in increased expression of SIRT1 mRNA; Rutin results in increased expression of SIRT1 protein CTD PMID:30365940 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SLAMF1 signaling lymphocytic activation molecule family member 1 increases expression
multiple interactions		 ISO Rutin results in increased expression of SLAMF1 protein
Lipopolysaccharides inhibits the reaction [Rutin results in increased expression of SLAMF1 protein]		 CTD PMID:28693884 NCBI chr 1:160,608,106...160,647,044
Ensembl chr 1:160,608,106...160,647,044 		JBrowse link
G SLC22A1 solute carrier family 22 member 1 multiple interactions ISO Rutin inhibits the reaction [Fructose results in decreased expression of SLC22A1 mRNA]; Rutin inhibits the reaction [Fructose results in decreased expression of SLC22A1 protein] CTD PMID:19605544 NCBI chr 6:160,121,815...160,158,718
Ensembl chr 6:160,121,815...160,158,718 		JBrowse link
G SLC22A12 solute carrier family 22 member 12 multiple interactions ISO Rutin inhibits the reaction [Fructose results in increased expression of SLC22A12 mRNA]; Rutin inhibits the reaction [Fructose results in increased expression of SLC22A12 protein] CTD PMID:19605544 NCBI chr11:64,591,220...64,602,344
Ensembl chr11:64,590,641...64,602,353 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 multiple interactions ISO Rutin inhibits the reaction [Fructose results in decreased expression of SLC22A2 mRNA]; Rutin inhibits the reaction [Fructose results in decreased expression of SLC22A2 protein] CTD PMID:19605544 NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638 		JBrowse link
G SLC22A6 solute carrier family 22 member 6 multiple interactions ISO Rutin inhibits the reaction [Fructose results in decreased expression of SLC22A6 mRNA]; Rutin inhibits the reaction [Fructose results in decreased expression of SLC22A6 protein] CTD PMID:19605544 NCBI chr11:62,976,597...62,984,967
Ensembl chr11:62,936,385...62,984,967 		JBrowse link
G SLC2A9 solute carrier family 2 member 9 multiple interactions ISO Rutin inhibits the reaction [Fructose results in increased expression of SLC2A9 mRNA SNP]; Rutin inhibits the reaction [Fructose results in increased expression of SLC2A9 protein SNP] CTD PMID:19605544 NCBI chr 4:9,771,025...10,040,270
Ensembl chr 4:9,771,153...10,054,936 		JBrowse link
G SLCO1B1 solute carrier organic anion transporter family member 1B1 multiple interactions EXP Rutin inhibits the reaction [SLCO1B1 protein results in increased import of Sulfobromophthalein] CTD PMID:22394605 NCBI chr12:21,131,194...21,239,796
Ensembl chr12:21,131,194...21,239,796 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 multiple interactions EXP Rutin inhibits the reaction [SLCO1B3 protein results in increased import of Sulfobromophthalein] CTD PMID:22394605 NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911 		JBrowse link
G SLCO2B1 solute carrier organic anion transporter family member 2B1 affects localization
multiple interactions		 EXP Rutin affects the localization of SLCO2B1 protein
Rutin promotes the reaction [SLCO2B1 protein results in increased uptake of Cholic Acid]; Rutin promotes the reaction [SLCO2B1 protein results in increased uptake of estrone sulfate]; Rutin promotes the reaction [SLCO2B1 protein results in increased uptake of Rosuvastatin Calcium]; Rutin promotes the reaction [SLCO2B1 protein results in increased uptake of Taurocholic Acid]		 CTD PMID:24285294 NCBI chr11:75,151,107...75,206,549
Ensembl chr11:75,100,563...75,206,549 		JBrowse link
G SMAD2 SMAD family member 2 multiple interactions ISO Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of SMAD2 mRNA] CTD PMID:27239252 NCBI chr18:47,808,957...47,930,872
Ensembl chr18:47,808,957...47,931,146 		JBrowse link
G SMAD4 SMAD family member 4 multiple interactions ISO Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of SMAD4 mRNA] CTD PMID:27239252 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 multiple interactions ISO Rutin inhibits the reaction [Fructose results in increased expression of SOCS3 protein] CTD PMID:22426011 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077 		JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions ISO Rutin inhibits the reaction [Carbon Tetrachloride results in decreased activity of SOD1 protein] CTD PMID:22902988 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SORD sorbitol dehydrogenase multiple interactions ISO [Rutin co-treated with Meloxicam] inhibits the reaction [Formaldehyde affects the activity of SORD protein]; Rutin inhibits the reaction [Formaldehyde affects the activity of SORD protein] CTD PMID:29315975 NCBI chr15:45,023,195...45,077,185
Ensembl chr15:45,023,147...45,077,185 		JBrowse link
G STAR steroidogenic acute regulatory protein increases expression ISO Rutin results in increased expression of STAR protein CTD PMID:29899696 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 multiple interactions ISO Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of STAT3 mRNA]; Rutin inhibits the reaction [Fructose results in increased phosphorylation of STAT3 protein] CTD PMID:22426011 PMID:26062544 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G TGFA transforming growth factor alpha multiple interactions EXP Rutin inhibits the reaction [TGFA protein affects the localization of EGFR protein] CTD PMID:21967610 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions ISO Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein]
Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of TGFB1 mRNA]; Rutin inhibits the reaction [Isoproterenol results in increased expression of TGFB1 mRNA]; Rutin inhibits the reaction [Isoproterenol results in increased expression of TGFB1 protein]; Rutin inhibits the reaction [Lipopolysaccharides results in increased expression of TGFB1 mRNA]		 CTD PMID:22902988 PMID:24117263 PMID:27239252 PMID:28693884 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TH tyrosine hydroxylase multiple interactions ISO Rutin inhibits the reaction [Oxidopamine results in decreased expression of TH mRNA] CTD PMID:25129099 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G TNF tumor necrosis factor multiple interactions
decreases expression		 EXP
ISO		 Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; Rutin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein]; Rutin inhibits the reaction [Glucose results in increased expression of TNF mRNA]; Rutin inhibits the reaction [Glucose results in increased expression of TNF protein]
Rutin results in decreased expression of TNF mRNA; Rutin results in decreased expression of TNF protein
Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; Rutin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Rutin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
Rutin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; Rutin inhibits the reaction [Cisplatin results in increased expression of TNF protein]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Rutin inhibits the reaction [Fructose results in increased expression of TNF protein]		 CTD PMID:14654164 PMID:18958421 PMID:19557821 PMID:21605616 PMID:21756928 More... NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TP53 tumor protein p53 multiple interactions ISO
EXP		 Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of TP53 mRNA]
Rutin inhibits the reaction [Cisplatin results in increased expression of TP53 protein]
Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of TRP53 protein]		 CTD PMID:27239252 PMID:29522708 PMID:29962303 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 multiple interactions ISO Rutin inhibits the reaction [Oxidopamine results in increased expression of UCHL1 mRNA] CTD PMID:25129099 NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions ISO Rutin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of VCAM1 protein] CTD PMID:25080890 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions
decreases expression		 EXP
ISO		 Rutin results in decreased secretion of and results in decreased expression of VEGFA protein; Rutin results in increased susceptibility to [Vitamin E results in decreased expression of VEGFA mRNA]; Rutin results in increased susceptibility to [Vitamin E results in decreased secretion of and results in decreased expression of VEGFA protein]; Vitamin E results in increased susceptibility to [Rutin results in decreased expression of VEGFA mRNA]; Vitamin E results in increased susceptibility to [Rutin results in decreased secretion of and results in decreased expression of VEGFA protein]
Rutin inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; Rutin inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]		 CTD PMID:20015448 PMID:33413359 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G XDH xanthine dehydrogenase multiple interactions ISO Rutin inhibits the reaction [Cyclophosphamide results in increased activity of XDH protein] CTD PMID:25753322 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
scutellarin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein multiple interactions ISO scutellarin inhibits the reaction [APP protein binds to APP protein] CTD PMID:17323972 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions ISO scutellarin inhibits the reaction [cobaltous chloride results in decreased expression of BCL2L1 mRNA] CTD PMID:18442013 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G CASP1 caspase 1 multiple interactions ISO scutellarin inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA] CTD PMID:37081038 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CASP3 caspase 3 multiple interactions ISO scutellarin inhibits the reaction [cobaltous chloride results in increased activity of CASP3 protein]
scutellarin affects the reaction [RIPK1 protein affects the reaction [Zearalenone results in increased cleavage of CASP3 protein]]; scutellarin inhibits the reaction [Zearalenone results in increased cleavage of CASP3 protein]		 CTD PMID:18442013 PMID:36252740 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G EP300 E1A binding protein p300 multiple interactions EXP scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] promotes the reaction [HIF1A protein binds to EP300 protein]] CTD PMID:25192544 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077 		JBrowse link
G FGF2 fibroblast growth factor 2 decreases expression ISO scutellarin results in decreased expression of FGF2 protein CTD PMID:16297343 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G GSDMD gasdermin D multiple interactions ISO scutellarin inhibits the reaction [Streptozocin results in increased expression of GSDMD protein] CTD PMID:37081038 NCBI chr 8:143,553,387...143,563,062
Ensembl chr 8:143,553,207...143,563,062 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions
decreases expression		 EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [scutellarin results in decreased expression of HIF1A protein]; epoxomicin inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]; epoxomicin inhibits the reaction [scutellarin results in decreased expression of HIF1A protein]; MG 262 inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]; MG 262 inhibits the reaction [scutellarin results in decreased expression of HIF1A protein]; scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose co-treated with Cycloheximide] results in decreased expression of HIF1A protein]; scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] promotes the reaction [HIF1A protein binds to EP300 protein]]; scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of and results in decreased ubiquitination of HIF1A protein]; scutellarin promotes the reaction [Cycloheximide inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]] CTD PMID:25192544 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G IL18 interleukin 18 multiple interactions ISO scutellarin inhibits the reaction [Streptozocin results in increased expression of IL18 protein] CTD PMID:37081038 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO scutellarin inhibits the reaction [Zearalenone results in increased expression of JUN protein] CTD PMID:36252740 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 multiple interactions ISO scutellarin inhibits the reaction [Zearalenone results in increased expression of MAP2K4 protein] CTD PMID:36252740 NCBI chr17:12,020,877...12,143,828
Ensembl chr17:12,020,829...12,143,830 		JBrowse link
G MKI67 marker of proliferation Ki-67 multiple interactions EXP scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of MKI67 mRNA]; scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of MKI67 protein] CTD PMID:25192544 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 multiple interactions ISO scutellarin inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein] CTD PMID:37081038 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108 		JBrowse link
G NOS2 nitric oxide synthase 2 decreases expression ISO scutellarin results in decreased expression of NOS2 protein CTD PMID:16297343 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 increases expression ISO scutellarin results in increased expression of NOS3 protein CTD PMID:16297343 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions EXP scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of PCNA mRNA]; scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of PCNA protein] CTD PMID:25192544 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626 		JBrowse link
G PKM pyruvate kinase M1/2 increases activity EXP scutellarin results in increased activity of PKM protein CTD PMID:25388478 NCBI chr15:72,199,029...72,231,591
Ensembl chr15:72,199,029...72,231,819 		JBrowse link
G PLA2G2A phospholipase A2 group IIA affects activity EXP scutellarin affects the activity of PLA2G2A protein CTD PMID:8190018 NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 multiple interactions ISO scutellarin affects the reaction [RIPK1 protein affects the reaction [Zearalenone results in increased cleavage of CASP3 protein]]; scutellarin inhibits the reaction [Zearalenone results in increased expression of RIPK1 mRNA]; scutellarin inhibits the reaction [Zearalenone results in increased expression of RIPK1 protein] CTD PMID:36252740 NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187 		JBrowse link
G VEGFA vascular endothelial growth factor A decreases expression
multiple interactions		 ISO
EXP		 scutellarin results in decreased expression of VEGFA protein
scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of VEGFA mRNA]; scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of VEGFA protein]		 CTD PMID:16297343 PMID:25192544 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26041
    chemical entity 26020
      atom 26016
        nonmetal atom 25505
          oxygen atom 24814
            oxygen molecular entity 24814
              flavonoids 12279
                flavonoid 7605
                  flavones 4702
                    glycosyloxyflavone 589
                      3',4',5,7-tetrahydroxy-3-methoxyflavone-7-O-alpha-L-rhamnopyranosyl-(1->6)-beta-D-glucopyranoside 0
                      3'-O-methyltricetin 3-O-alpha-L-rhamnopyranoside 0
                      3-O-methylquercetin 7-O-beta-glucopyranosyl-4'-O-beta-D-glucopyranoside 0
                      4',5,7-trihydroxy-3-methoxyflavone-7-O-alpha-L-arabinofuranosyl(1->6)-beta-D-glucopyranoside 0
                      4',5,7-trihydroxy-3-methoxyflavone-7-O-beta-D-glucopyranoside 0
                      4',5,7-trihydroxy-3-methoxyflavone-7-O-rutinoside 0
                      4'-O-beta-glucosyl-7-O-(6-O-sinapoylglucosyl)isovitexin 0
                      4'-O-beta-glucosyl-7-O-(6-O-sinapoylglucosyl)tricin 0
                      5,6,7,4'-tetrahydroxyflavonol-3-O-rutinoside 0
                      5-galloylquercetin-3-O-alpha-L-arabinofuranoside 0
                      6-hydroxyluteolin 7-O-laminaribioside 0
                      6-methoxyluteolin 7-alpha-L-rhamnoside 0
                      7-O-(6-feruoylglucosyl)isoorientin 0
                      7-O-(6-p-coumaroylglucosyl)chrysoeriol 0
                      7-O-(6-sinapoylglucosyl)isoorientin 0
                      7-O-(6-sinapoylglucosyl)isoscoparin 0
                      7-O-(6-sinapoylglucosyl)isovitexin 0
                      7-O-(beta-D-glucosyl)isovitexin 0
                      7-O-[6-(6-methoxycaffeoyl)glucosyl]isovitexin 0
                      7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucosyl]chrysoeriol 0
                      7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucosyl]isoorientin 0
                      7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucosyl]isoscoparin 0
                      7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucosyl]isovitexin 0
                      7-O-[beta-D-arabinopyranosyl-(1->6)-beta-D-glucosyl]apigenin 0
                      7-O-[beta-D-arabinopyranosyl-(1->6)-beta-D-glucosyl]luteolin 0
                      7-O-beta-D-glucosylisoscoparin 0
                      7-O-methoxy gossypetin 3-O-rutinoside 0
                      7-hydroxyflavanone 7-O-[beta-L-rhamnosyl-(1->2)-beta-D-glucoside] 0
                      8-C-alpha-L-arabinopyranosyl-7-O-beta-D-glucopyranosylnaringenin 0
                      acacetin-7-O-beta-D-galactopyranoside 0
                      afzelin 3
                      apigenin 7-O-beta-D-glucoside 1
                      apigenin 7-O-beta-L-glucoside 0
                      apigenin 7-O-neohesperidoside 0
                      apigenin-7-O-gentiobioside 0
                      apiin + 0
                      baicalin 61
                      chrysoeriol 7-O-gentiobioside 0
                      diandraflavone 0
                      diosmin 26
                      flavonol 3-O-(6-O-malonyl-beta-D-glucoside) 0
                      flavonol 3-O-D-galactoside 0
                      flavonol 3-O-D-xylosyl-D-galactoside 0
                      flavonol 3-O-D-xylosyl-D-glucoside 0
                      flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside]s + 0
                      flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside]s 0
                      flavonol 3-O-[beta-D-xylosyl-(1->2)-beta-D-glycoside]s + 0
                      flavonol 3-O-beta-D-glucoside + 0
                      flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside 0
                      flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside 0
                      flavonol 3-O-glycoside 0
                      flavonol 7-O-beta-D-glucoside + 0
                      gossypetin 8-rhamnoside 0
                      gossypin 29
                      hermannioside B 0
                      icariin 83
                      icariside II 35
                      isoorientin 7-O-glucoside 0
                      isorhamnetin 3-O-alpha-L-[6''''-p-coumaroyl-beta-D-glucopyranosyl-(1->2)-rhamnopyranoside] 0
                      isorhamnetin 3-O-beta-D-galactopyranoside 0
                      isorhamnetin 3-O-beta-D-glucopyranoside 0
                      isorhamnetin 3-O-beta-L-galactopyranoside 0
                      isorhamnetin 3-O-beta-L-glucopyranoside 0
                      isorhamnetin 3-O-robinobioside 0
                      isorhamnetin 4'-O-beta-D-glucopyranoside 0
                      isorhamnetin 4'-O-beta-L-glucopyranoside 0
                      isorhamnetin 7-O-beta-D-glucopyranoside 0
                      isorhamnetin 7-O-beta-L-glucopyranoside 0
                      isorhamnetin-3-O-rutinoside 0
                      kaempferol 3,7-di-O-alpha-L-rhamnoside 0
                      kaempferol 3-O-(5-O-acetyl-alpha-D-apiofuranosyl)-7-O-alpha-L-rhamnopyranoside 0
                      kaempferol 3-O-[alpha-L-rhamnopyranosyl(1->2)-beta-D-galactopyranosyl]-7-O-alpha-L-rhamnopyranoside 0
                      kaempferol 3-O-alpha-L-[6'''-p-coumaroyl-beta-D-glucopyranosyl-(1->2)-rhamnopyranoside] 0
                      kaempferol 3-O-alpha-L-arabinopyranosyl-7-O-alpha-L-rhamnopyranoside 0
                      kaempferol 3-O-beta-D-allopyranoside 0
                      kaempferol 3-O-beta-D-apiofuranosyl-7-O-alpha-L-rhamnopyranoside 0
                      kaempferol 3-O-beta-D-galactopyranosyl-7-O-alpha-L-rhamnopyranoside 0
                      kaempferol 3-O-beta-D-galactoside 1
                      kaempferol 3-O-beta-D-glucosylgalactoside 0
                      kaempferol 3-O-beta-D-xyloside 0
                      kaempferol 3-O-gentiobioside-7-O-rhamnoside 0
                      kaempferol 7-O-(2,3-di-E-p-coumaroyl-alpha-L-rhamnopyranoside) 0
                      kaempferol 7-O-(2-E-p-coumaroyl-alpha-L-rhamnopyranoside) 0
                      kaempferol 7-O-beta-D-galactopyranoside 0
                      kaempferol O-glucoside + 15
                      kaempferol O-glucuronide + 0
                      laricitrin 3-glucoside 0
                      luteolin 7-O-(6-O-malonyl-beta-D-glucoside) 0
                      luteolin 7-O-beta-D-glucoside + 27
                      luteolin 7-O-beta-D-glucoside-4'-(Z-2-methyl-2-butenoate) 0
                      luteolin 7-O-beta-D-glucosiduronic acid 0
                      luteolin 7-O-neohesperidoside 0
                      luteolin O-glucuronoside + 0
                      luteolin-4'-O-beta-D-glucopyranoside 0
                      luteolin-7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] 0
                      luteolin-7-O-alpha-L-rhamnoside 0
                      malonylapiin 0
                      matsudone A 0
                      montbretin A 0
                      multiflorin B 0
                      multinoside A 0
                      myricetin 3-O-[(6-O-acetyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside] 0
                      myricetin 3-O-[(6-O-caffeoyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside] 0
                      myricetin 3-O-[(6-O-trans-4-coumaroyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside] 0
                      myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] + 0
                      myricetin 3-O-beta-D-galactopyranoside 0
                      myricetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside 0
                      myricetin 3-O-beta-L-galactopyranoside 0
                      myricetin O-glucoside + 0
                      myricetin O-glucuronide + 0
                      myricetin-3-O-arabinofuranoside 0
                      myricetin-3-O-beta-D-xylopyranoside 0
                      myricitrin + 27
                      myricitrin-5-methyl ether 0
                      oroxylin A 7-O-beta-D-glucuronide 0
                      pectolinarin 0
                      plantaginin 0
                      quercetin O-glycoside + 474
                      robinin 1
                      scutellarin 20
                      syringetin 3-glucoside 0
                      theograndin II 0
                      tribuloside 0
                      tricin 4'-O-(erythro-beta-guaiacylglyceryl) ether 7-O-beta-D-glucopyranoside 0
                      tricin 4'-O-(threo-beta-guaiacylglyceryl) ether 7-O-beta-D-glucopyranoside 0
                      tricin 5-O-beta-D-glucoside 0
                      tricin 7-O-(6''-O-malonyl)-beta-D-glucopyranoside 0
                      tricin 7-O-[sinapoyl]-glucoside 0
                      tricin 7-O-beta-D-glucoside 0
                      tricin 7-O-glucoside + 0
                      tricin 7-O-neohesperidoside 0
                      viscumneoside IV + 0
                      viscumneoside VII 0
                      wogonin 7-O-beta-D-glucuronide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26041
    subatomic particle 26016
      composite particle 26016
        hadron 26016
          baryon 26016
            nucleon 26016
              atomic nucleus 26016
                atom 26016
                  main group element atom 25841
                    p-block element atom 25841
                      carbon group element atom 25441
                        carbon atom 25399
                          organic molecular entity 25399
                            organic molecule 25228
                              organic cyclic compound 24281
                                organic heterocyclic compound 22324
                                  oxacycle 19999
                                    benzopyran 12753
                                      1-benzopyran 12488
                                        flavonoid 7605
                                          anthoxanthin 4702
                                            flavones 4702
                                              glycosyloxyflavone 589
                                                3',4',5,7-tetrahydroxy-3-methoxyflavone-7-O-alpha-L-rhamnopyranosyl-(1->6)-beta-D-glucopyranoside 0
                                                3'-O-methyltricetin 3-O-alpha-L-rhamnopyranoside 0
                                                3-O-methylquercetin 7-O-beta-glucopyranosyl-4'-O-beta-D-glucopyranoside 0
                                                4',5,7-trihydroxy-3-methoxyflavone-7-O-alpha-L-arabinofuranosyl(1->6)-beta-D-glucopyranoside 0
                                                4',5,7-trihydroxy-3-methoxyflavone-7-O-beta-D-glucopyranoside 0
                                                4',5,7-trihydroxy-3-methoxyflavone-7-O-rutinoside 0
                                                4'-O-beta-glucosyl-7-O-(6-O-sinapoylglucosyl)isovitexin 0
                                                4'-O-beta-glucosyl-7-O-(6-O-sinapoylglucosyl)tricin 0
                                                5,6,7,4'-tetrahydroxyflavonol-3-O-rutinoside 0
                                                5-galloylquercetin-3-O-alpha-L-arabinofuranoside 0
                                                6-hydroxyluteolin 7-O-laminaribioside 0
                                                6-methoxyluteolin 7-alpha-L-rhamnoside 0
                                                7-O-(6-feruoylglucosyl)isoorientin 0
                                                7-O-(6-p-coumaroylglucosyl)chrysoeriol 0
                                                7-O-(6-sinapoylglucosyl)isoorientin 0
                                                7-O-(6-sinapoylglucosyl)isoscoparin 0
                                                7-O-(6-sinapoylglucosyl)isovitexin 0
                                                7-O-(beta-D-glucosyl)isovitexin 0
                                                7-O-[6-(6-methoxycaffeoyl)glucosyl]isovitexin 0
                                                7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucosyl]chrysoeriol 0
                                                7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucosyl]isoorientin 0
                                                7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucosyl]isoscoparin 0
                                                7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucosyl]isovitexin 0
                                                7-O-[beta-D-arabinopyranosyl-(1->6)-beta-D-glucosyl]apigenin 0
                                                7-O-[beta-D-arabinopyranosyl-(1->6)-beta-D-glucosyl]luteolin 0
                                                7-O-beta-D-glucosylisoscoparin 0
                                                7-O-methoxy gossypetin 3-O-rutinoside 0
                                                7-hydroxyflavanone 7-O-[beta-L-rhamnosyl-(1->2)-beta-D-glucoside] 0
                                                8-C-alpha-L-arabinopyranosyl-7-O-beta-D-glucopyranosylnaringenin 0
                                                acacetin-7-O-beta-D-galactopyranoside 0
                                                afzelin 3
                                                apigenin 7-O-beta-D-glucoside 1
                                                apigenin 7-O-beta-L-glucoside 0
                                                apigenin 7-O-neohesperidoside 0
                                                apigenin-7-O-gentiobioside 0
                                                apiin + 0
                                                baicalin 61
                                                chrysoeriol 7-O-gentiobioside 0
                                                diandraflavone 0
                                                diosmin 26
                                                flavonol 3-O-(6-O-malonyl-beta-D-glucoside) 0
                                                flavonol 3-O-D-galactoside 0
                                                flavonol 3-O-D-xylosyl-D-galactoside 0
                                                flavonol 3-O-D-xylosyl-D-glucoside 0
                                                flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside]s + 0
                                                flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside]s 0
                                                flavonol 3-O-[beta-D-xylosyl-(1->2)-beta-D-glycoside]s + 0
                                                flavonol 3-O-beta-D-glucoside + 0
                                                flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside 0
                                                flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside 0
                                                flavonol 3-O-glycoside 0
                                                flavonol 7-O-beta-D-glucoside + 0
                                                gossypetin 8-rhamnoside 0
                                                gossypin 29
                                                hermannioside B 0
                                                icariin 83
                                                icariside II 35
                                                isoorientin 7-O-glucoside 0
                                                isorhamnetin 3-O-alpha-L-[6''''-p-coumaroyl-beta-D-glucopyranosyl-(1->2)-rhamnopyranoside] 0
                                                isorhamnetin 3-O-beta-D-galactopyranoside 0
                                                isorhamnetin 3-O-beta-D-glucopyranoside 0
                                                isorhamnetin 3-O-beta-L-galactopyranoside 0
                                                isorhamnetin 3-O-beta-L-glucopyranoside 0
                                                isorhamnetin 3-O-robinobioside 0
                                                isorhamnetin 4'-O-beta-D-glucopyranoside 0
                                                isorhamnetin 4'-O-beta-L-glucopyranoside 0
                                                isorhamnetin 7-O-beta-D-glucopyranoside 0
                                                isorhamnetin 7-O-beta-L-glucopyranoside 0
                                                isorhamnetin-3-O-rutinoside 0
                                                kaempferol 3,7-di-O-alpha-L-rhamnoside 0
                                                kaempferol 3-O-(5-O-acetyl-alpha-D-apiofuranosyl)-7-O-alpha-L-rhamnopyranoside 0
                                                kaempferol 3-O-[alpha-L-rhamnopyranosyl(1->2)-beta-D-galactopyranosyl]-7-O-alpha-L-rhamnopyranoside 0
                                                kaempferol 3-O-alpha-L-[6'''-p-coumaroyl-beta-D-glucopyranosyl-(1->2)-rhamnopyranoside] 0
                                                kaempferol 3-O-alpha-L-arabinopyranosyl-7-O-alpha-L-rhamnopyranoside 0
                                                kaempferol 3-O-beta-D-allopyranoside 0
                                                kaempferol 3-O-beta-D-apiofuranosyl-7-O-alpha-L-rhamnopyranoside 0
                                                kaempferol 3-O-beta-D-galactopyranosyl-7-O-alpha-L-rhamnopyranoside 0
                                                kaempferol 3-O-beta-D-galactoside 1
                                                kaempferol 3-O-beta-D-glucosylgalactoside 0
                                                kaempferol 3-O-beta-D-xyloside 0
                                                kaempferol 3-O-gentiobioside-7-O-rhamnoside 0
                                                kaempferol 7-O-(2,3-di-E-p-coumaroyl-alpha-L-rhamnopyranoside) 0
                                                kaempferol 7-O-(2-E-p-coumaroyl-alpha-L-rhamnopyranoside) 0
                                                kaempferol 7-O-beta-D-galactopyranoside 0
                                                kaempferol O-glucoside + 15
                                                kaempferol O-glucuronide + 0
                                                laricitrin 3-glucoside 0
                                                luteolin 7-O-(6-O-malonyl-beta-D-glucoside) 0
                                                luteolin 7-O-beta-D-glucoside + 27
                                                luteolin 7-O-beta-D-glucoside-4'-(Z-2-methyl-2-butenoate) 0
                                                luteolin 7-O-beta-D-glucosiduronic acid 0
                                                luteolin 7-O-neohesperidoside 0
                                                luteolin O-glucuronoside + 0
                                                luteolin-4'-O-beta-D-glucopyranoside 0
                                                luteolin-7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] 0
                                                luteolin-7-O-alpha-L-rhamnoside 0
                                                malonylapiin 0
                                                matsudone A 0
                                                montbretin A 0
                                                multiflorin B 0
                                                multinoside A 0
                                                myricetin 3-O-[(6-O-acetyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside] 0
                                                myricetin 3-O-[(6-O-caffeoyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside] 0
                                                myricetin 3-O-[(6-O-trans-4-coumaroyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside] 0
                                                myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] + 0
                                                myricetin 3-O-beta-D-galactopyranoside 0
                                                myricetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside 0
                                                myricetin 3-O-beta-L-galactopyranoside 0
                                                myricetin O-glucoside + 0
                                                myricetin O-glucuronide + 0
                                                myricetin-3-O-arabinofuranoside 0
                                                myricetin-3-O-beta-D-xylopyranoside 0
                                                myricitrin + 27
                                                myricitrin-5-methyl ether 0
                                                oroxylin A 7-O-beta-D-glucuronide 0
                                                pectolinarin 0
                                                plantaginin 0
                                                quercetin O-glycoside + 474
                                                robinin 1
                                                scutellarin 20
                                                syringetin 3-glucoside 0
                                                theograndin II 0
                                                tribuloside 0
                                                tricin 4'-O-(erythro-beta-guaiacylglyceryl) ether 7-O-beta-D-glucopyranoside 0
                                                tricin 4'-O-(threo-beta-guaiacylglyceryl) ether 7-O-beta-D-glucopyranoside 0
                                                tricin 5-O-beta-D-glucoside 0
                                                tricin 7-O-(6''-O-malonyl)-beta-D-glucopyranoside 0
                                                tricin 7-O-[sinapoyl]-glucoside 0
                                                tricin 7-O-beta-D-glucoside 0
                                                tricin 7-O-glucoside + 0
                                                tricin 7-O-neohesperidoside 0
                                                viscumneoside IV + 0
                                                viscumneoside VII 0
                                                wogonin 7-O-beta-D-glucuronide 0
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