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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:glycosyloxyflavone
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Accession:CHEBI:50018 term browser browse the term
Definition:A member of the class of flavones having one or more glycosyl residues attached at unspecified positions.
Synonyms:related_synonym: flavone glycoside;   flavone glycosides;   glycosyloxyflavones


show annotations for term's descendants           Sort by:
afzelin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mitf melanocyte inducing transcription factor increases expression ISO afzelin results in increased expression of MITF mRNA; afzelin results in increased expression of MITF protein CTD PMID:27287415 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145 		JBrowse link
G Tyr tyrosinase multiple interactions
increases expression		 ISO afzelin results in increased expression of and results in increased activity of TYR protein
afzelin results in increased expression of TYR mRNA		 CTD PMID:27287415 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207 		JBrowse link
G Tyrp1 tyrosinase-related protein 1 increases expression ISO afzelin results in increased expression of TYRP1 mRNA; afzelin results in increased expression of TYRP1 protein CTD PMID:27287415 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516 		JBrowse link
apigenin 7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gypa glycophorin A increases expression ISO apigetrin results in increased expression of GYPA protein CTD PMID:25058688 NCBI chr19:27,450,311...27,465,940
Ensembl chr19:27,450,308...27,465,822 		JBrowse link
baicalin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases expression
multiple interactions		 EXP baicalin results in increased expression of ACHE mRNA
baicalin results in increased expression of and results in increased activity of ACHE protein		 CTD PMID:27019979 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Ahr aryl hydrocarbon receptor increases activity ISO baicalin results in increased activity of AHR protein CTD PMID:17869316 PMID:26204831 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions EXP baicalin inhibits the reaction [Hydrogen Peroxide affects the localization of and results in increased activity of ALOX5 protein] CTD PMID:20139896 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Angpt1 angiopoietin 1 multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in decreased expression of ANGPT1 mRNA] CTD PMID:34414639 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Atf2 activating transcription factor 2 multiple interactions EXP baicalin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of ATF2 protein] CTD PMID:24312512 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 ISO
EXP		 baicalin results in increased expression of BAX protein
baicalin inhibits the reaction [Rotenone affects the expression of BAX protein]		 CTD PMID:21457722 PMID:25423838 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP baicalin inhibits the reaction [Rotenone affects the expression of BCL2 protein] CTD PMID:25423838 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP baicalin inhibits the reaction [Rotenone affects the expression of CASP3 protein] CTD PMID:25423838 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO baicalin results in decreased expression of CCNA2 protein CTD PMID:21457722 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnd1 cyclin D1 increases expression
decreases expression
multiple interactions		 ISO baicalin results in increased expression of CCND1 mRNA
baicalin results in decreased expression of CCND1 protein
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of CCND1 mRNA]		 CTD PMID:19160421 PMID:21457722 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions EXP baicalin inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA] CTD PMID:19474275 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A1 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A1 protein]; baicalin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
baicalin results in increased expression of CYP1A1 mRNA; baicalin results in increased expression of CYP1A1 protein		 CTD PMID:18451504 PMID:26204831 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression		 ISO 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A2 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A2 protein]
resveratrol inhibits the reaction [baicalin results in increased expression of CYP1A2 mRNA]; resveratrol inhibits the reaction [baicalin results in increased expression of CYP1A2 protein]
baicalin results in increased expression of CYP1A2 mRNA; baicalin results in increased expression of CYP1A2 protein		 CTD PMID:26204831 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO baicalin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; baicalin inhibits the reaction [EGF protein results in increased phosphorylation of ELK1 protein] CTD PMID:25625231 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO baicalin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions ISO baicalin inhibits the reaction [EGF protein results in increased phosphorylation of ELK1 protein] CTD PMID:25625231 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO baicalin inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:29031535 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Foxa2 forkhead box A2 decreases expression ISO baicalin results in decreased expression of FOXA2 mRNA; baicalin results in decreased expression of FOXA2 protein CTD PMID:32687838 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP baicalin inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GOT1 protein] CTD PMID:15645217 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP baicalin inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GPT protein] CTD PMID:15645217 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 increases expression
multiple interactions		 ISO baicalin results in increased expression of HES1 mRNA
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HES1 mRNA]		 CTD PMID:19160421 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 increases expression
multiple interactions		 ISO baicalin results in increased expression of HEY1 mRNA
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HEY1 mRNA]		 CTD PMID:19160421 NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 multiple interactions
increases expression		 ISO N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HEY2 mRNA] CTD PMID:19160421 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 ISO
EXP		 baicalin promotes the reaction [Carbon Tetrachloride results in increased expression of HMOX1 mRNA]; baicalin promotes the reaction [Carbon Tetrachloride results in increased expression of HMOX1 protein]
baicalin results in increased expression of HMOX1 mRNA; baicalin results in increased expression of HMOX1 protein		 CTD PMID:16824337 PMID:18187930 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnf1a HNF1 homeobox A decreases expression
multiple interactions		 ISO baicalin results in decreased expression of HNF1A protein
baicalin results in decreased expression of HNF1A mRNA; baicalin results in decreased expression of HNF1A protein
baicalin inhibits the reaction [HNF4A protein binds to HNF1A promoter]; HNF1A protein promotes the reaction [baicalin results in decreased secretion of Hepatitis B Surface Antigens]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A mRNA]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A protein]		 CTD PMID:32687838 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases expression
multiple interactions		 ISO baicalin results in decreased expression of HNF4A protein
baicalin inhibits the reaction [HNF4A protein binds to HNF1A promoter]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A mRNA]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A protein]; HNF4A protein promotes the reaction [baicalin results in decreased secretion of Hepatitis B Surface Antigens]
baicalin results in decreased expression of HNF4A mRNA; baicalin results in decreased expression of HNF4A protein		 CTD PMID:32687838 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of HSPB1 protein] CTD PMID:34414639 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO baicalin inhibits the reaction [Palmitic Acid results in increased secretion of IL1B protein] CTD PMID:29031535 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions		 EXP
ISO		 baicalin results in decreased expression of IL6 mRNA; baicalin results in decreased expression of IL6 protein
baicalin inhibits the reaction [Palmitic Acid results in increased secretion of IL6 protein]		 CTD PMID:22019745 PMID:29031535 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein] CTD PMID:34414639 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein] CTD PMID:34414639 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor decreases expression EXP baicalin results in decreased expression of MYD88 protein CTD PMID:22019745 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression EXP baicalin results in increased expression of NFKBIA protein CTD PMID:22019745 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO baicalin inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 protein] CTD PMID:29031535 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression		 EXP
ISO		 baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; mifobate inhibits the reaction [baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]]
baicalin results in decreased expression of NOS2 mRNA; baicalin results in decreased expression of NOS2 protein
baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 mRNA]; baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein]		 CTD PMID:18187930 PMID:22019745 PMID:24312512 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Notch1 notch receptor 1 increases activity
increases expression		 ISO baicalin results in increased activity of NOTCH1 protein
baicalin results in increased expression of NOTCH1 mRNA		 CTD PMID:19160421 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Pkm pyruvate kinase M1/2 increases activity ISO baicalin results in increased activity of PKM protein CTD PMID:25388478 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions EXP baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of and results in decreased activity of PPARG protein] CTD PMID:24312512 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Prima1 proline rich membrane anchor 1 increases expression EXP baicalin results in increased expression of PRIMA1 mRNA CTD PMID:27019979 NCBI chr 6:122,338,365...122,390,955
Ensembl chr 6:122,338,370...122,389,921 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression EXP baicalin results in decreased expression of PTGS2 mRNA; baicalin results in decreased expression of PTGS2 protein CTD PMID:22019745 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP baicalin affects the localization of and results in decreased expression of RELA protein CTD PMID:22019745 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tek TEK receptor tyrosine kinase multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in decreased expression of TEK mRNA] CTD PMID:34414639 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in decreased expression of TGFB1 mRNA]; baicalin inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA] CTD PMID:19474275 PMID:34414639 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tlr4 toll-like receptor 4 decreases expression
multiple interactions		 EXP baicalin results in decreased expression of TLR4 protein
baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]		 CTD PMID:22019745 PMID:24312512 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression		 ISO
EXP		 baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]; baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]
baicalin results in decreased expression of TNF mRNA; baicalin results in decreased expression of TNF protein
baicalin inhibits the reaction [Paraquat results in increased expression of TNF protein]		 CTD PMID:16824337 PMID:18187930 PMID:22019745 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO baicalin results in increased expression of TP53 protein CTD PMID:21457722 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Txnip thioredoxin interacting protein multiple interactions ISO baicalin inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein]; dorsomorphin inhibits the reaction [baicalin inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein]] CTD PMID:29031535 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886 		JBrowse link
G Usp27x ubiquitin specific peptidase 27, X-linked multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in increased expression of USP27X protein] CTD PMID:34414639 NCBI chr  X:15,123,642...15,126,855
Ensembl chr  X:15,124,596...15,125,912 		JBrowse link
G Vegfc vascular endothelial growth factor C multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in decreased expression of VEGFC mRNA] CTD PMID:34414639 NCBI chr16:37,712,408...37,827,657
Ensembl chr16:37,712,262...37,827,848 		JBrowse link
G Xdh xanthine dehydrogenase multiple interactions ISO baicalin inhibits the reaction [[Biological Products co-treated with potassium oxonate] results in increased activity of XDH protein] CTD PMID:34044073 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
diosmin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO Diosmin binds to and results in increased activity of AHR protein CTD PMID:14644660 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions EXP Diosmin inhibits the reaction [Lipopolysaccharides results in increased expression of BAD protein] CTD PMID:21477647 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Diosmin inhibits the reaction [Benzo(a)pyrene results in increased expression of BAX protein] CTD PMID:32061149 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP
ISO		 [Diosmin co-treated with Lipopolysaccharides] results in increased expression of BCL2 protein
Diosmin inhibits the reaction [Benzo(a)pyrene results in decreased expression of BCL2 protein]		 CTD PMID:21477647 PMID:32061149 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO		 Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of CASP3 protein]; Diosmin inhibits the reaction [Acetic Acid results in increased expression of CASP3 protein]; Diosmin inhibits the reaction [Lipopolysaccharides results in increased activity of CASP3 protein]
Diosmin inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]		 CTD PMID:21477647 PMID:23665045 PMID:29187079 PMID:32061149 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 multiple interactions EXP Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of CASP7 protein] CTD PMID:23665045 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp9 caspase 9 multiple interactions EXP Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of CASP9 protein] CTD PMID:23665045 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions EXP Diosmin inhibits the reaction [2-Acetylaminofluorene results in decreased expression of CAT protein]; Diosmin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein] CTD PMID:22056647 PMID:23665045 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of CYP2E1 protein] CTD PMID:23665045 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP
ISO		 Diosmin inhibits the reaction [2-Acetylaminofluorene results in decreased expression of GSR protein]
Diosmin inhibits the reaction [Benzo(a)pyrene results in decreased expression of GSR protein]		 CTD PMID:23665045 PMID:32061149 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Diosmin inhibits the reaction [Benzo(a)pyrene results in increased expression of IL6 protein] CTD PMID:32061149 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions EXP Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of MKI67 protein]; Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of MKI67 protein] CTD PMID:23665045 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Diosmin inhibits the reaction [Acetic Acid results in increased activity of MPO protein] CTD PMID:29187079 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of NOS2 protein] CTD PMID:23665045 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Diosmin inhibits the reaction [Benzo(a)pyrene results in increased cleavage of PARP1 protein] CTD PMID:32061149 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of PCNA protein]; Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of PCNA protein] CTD PMID:23665045 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO		 Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of PTGS2 protein]; Diosmin inhibits the reaction [Acetic Acid results in increased expression of PTGS2 protein]
Diosmin inhibits the reaction [Benzo(a)pyrene results in increased expression of PTGS2 protein]		 CTD PMID:23665045 PMID:29187079 PMID:32061149 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Diosmin inhibits the reaction [Benzo(a)pyrene results in increased expression of RELA protein] CTD PMID:32061149 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of TNF protein]; Diosmin inhibits the reaction [Acetic Acid results in increased expression of TNF protein]; Diosmin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:21477647 PMID:23665045 PMID:29187079 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TP53 protein] CTD PMID:23665045 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Xdh xanthine dehydrogenase multiple interactions EXP
ISO		 Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of XDH protein]
Diosmin inhibits the reaction [Benzo(a)pyrene results in increased expression of XDH protein]		 CTD PMID:23665045 PMID:32061149 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
icariin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 increases expression ISO icariin results in increased expression of ADRB1 mRNA CTD PMID:16490167 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation		 EXP
ISO		 [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of AKT1 mRNA; [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of and results in decreased phosphorylation of AKT1 protein
icariin results in increased phosphorylation of AKT1 protein
afimoxifene inhibits the reaction [icariin results in increased phosphorylation of AKT1 protein]; icariin affects the reaction [Diethylhexyl Phthalate affects the phosphorylation of AKT1 protein]; icariin inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of AKT1 protein]; icariin inhibits the reaction [MK 2206 results in decreased phosphorylation of AKT1 protein]		 CTD PMID:32344236 PMID:35259346 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G App amyloid beta precursor protein multiple interactions EXP icariin inhibits the reaction [APP protein alternative form results in decreased expression of SOD2 mRNA]; icariin inhibits the reaction [APP protein alternative form results in increased expression of BACE1 mRNA] CTD PMID:19782061 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Bace1 beta-secretase 1 multiple interactions EXP icariin inhibits the reaction [APP protein alternative form results in increased expression of BACE1 mRNA] CTD PMID:19782061 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression
multiple interactions		 EXP
ISO		 icariin affects the expression of BCL2 protein
icariin inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in decreased expression of BCL2 protein]		 CTD PMID:25472572 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l11 Bcl2-like 11 affects expression
multiple interactions		 EXP
ISO		 icariin affects the expression of BCL2L11 protein
icariin inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in increased expression of BCL2L11 protein]		 CTD PMID:25472572 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression
multiple interactions		 ISO
EXP		 icariin results in increased expression of BGLAP mRNA
NOG protein inhibits the reaction [icariin results in increased expression of BGLAP mRNA]; SMAD6 protein inhibits the reaction [icariin results in increased expression of BGLAP mRNA]		 CTD PMID:18236786 PMID:18295595 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression
multiple interactions		 ISO
EXP		 icariin results in increased expression of BMP2 mRNA
NOG protein inhibits the reaction [icariin results in increased expression of BMP2 mRNA]		 CTD PMID:15724410 PMID:16543677 PMID:17355822 PMID:19747809 PMID:20019778 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression EXP
ISO		 icariin results in increased expression of BMP4 mRNA CTD PMID:18295595 PMID:20019778 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Cartpt CART prepropeptide increases expression ISO icariin results in increased expression of CARTPT mRNA; icariin results in increased expression of CARTPT protein CTD PMID:19858766 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Casp1 caspase 1 increases cleavage ISO icariin results in increased cleavage of CASP1 protein CTD PMID:35532261 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases phosphorylation		 ISO [naphthol AS-E phosphate co-treated with icariin] results in increased phosphorylation of CREB1 protein; icariin inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of CREB1 protein]; icariin inhibits the reaction [MK 2206 results in decreased phosphorylation of CREB1 protein]
icariin results in increased phosphorylation of CREB1 protein		 CTD PMID:35259346 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression
multiple interactions		 ISO icariin results in increased expression of CYP11A1 mRNA; icariin results in increased expression of CYP11A1 protein
[icariin co-treated with Diethylhexyl Phthalate] results in increased expression of CYP11A1 mRNA; [icariin co-treated with naphthol AS-E phosphate] results in decreased expression of CYP11A1 protein; [MK 2206 co-treated with icariin] results in increased expression of CYP11A1 mRNA; icariin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of CYP11A1 protein]; icariin inhibits the reaction [MK 2206 results in decreased expression of CYP11A1 protein]		 CTD PMID:31175881 PMID:35259346 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions EXP [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of and results in decreased phosphorylation of EGFR protein; [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of EGFR mRNA CTD PMID:32344236 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 ISO icariin results in increased expression of FOS mRNA; icariin results in increased expression of FOS protein
SB 203580 inhibits the reaction [icariin results in increased expression of FOS protein]; U 0126 inhibits the reaction [icariin results in increased expression of FOS protein]		 CTD PMID:18423597 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Foxo3 forkhead box O3 affects localization
multiple interactions		 EXP
ISO		 icariin affects the localization of FOXO3 protein
icariin inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in increased acetylation of and results in increased expression of FOXO3 protein]; Niacinamide inhibits the reaction [icariin inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in increased acetylation of and results in increased expression of FOXO3 protein]]		 CTD PMID:25472572 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Gata4 GATA binding protein 4 increases expression ISO icariin results in increased expression of GATA4 mRNA CTD PMID:16490167 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 increases expression
multiple interactions		 ISO icariin results in increased expression of HSD3B1 mRNA; icariin results in increased expression of HSD3B1 protein
icariin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of HSD3B1 mRNA]; icariin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of HSD3B1 protein]		 CTD PMID:31175881 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Id1 inhibitor of DNA binding 1 increases expression ISO icariin results in increased expression of ID1 mRNA CTD PMID:18295595 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419 		JBrowse link
G Igf1 insulin-like growth factor 1 increases expression EXP icariin results in increased expression of IGF1 mRNA CTD PMID:18236786 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression		 EXP
ISO		 [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased secretion of IL1B protein
icariin results in increased expression of IL1B protein		 CTD PMID:32344236 PMID:35532261 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 affects expression
multiple interactions		 EXP icariin affects the expression of IL6 protein
[paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased secretion of IL6 protein		 CTD PMID:25472572 PMID:32344236 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 ISO SB 203580 inhibits the reaction [icariin results in increased expression of JUN protein]; U 0126 inhibits the reaction [icariin results in increased expression of JUN protein]
icariin results in increased expression of JUN mRNA; icariin results in increased expression of JUN protein		 CTD PMID:18423597 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation		 ISO U 0126 inhibits the reaction [icariin results in increased phosphorylation of MAPK1 protein] CTD PMID:18423597 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 ISO U 0126 inhibits the reaction [icariin results in increased phosphorylation of MAPK3 protein] CTD PMID:18423597 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mef2c myocyte enhancer factor 2C multiple interactions
affects localization
increases expression		 ISO SB 203580 inhibits the reaction [icariin affects the localization of MEF2C protein]; SB 203580 inhibits the reaction [icariin results in increased expression of MEF2C mRNA]; U 0126 inhibits the reaction [icariin affects the localization of MEF2C protein]; U 0126 inhibits the reaction [icariin results in increased expression of MEF2C mRNA] CTD PMID:18423597 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mir1224 microRNA 1224 decreases expression ISO icariin results in decreased expression of MIR1224 mRNA CTD PMID:30533443 NCBI chr11:80,306,902...80,306,986
Ensembl chr11:80,306,902...80,306,986 		JBrowse link
G Mir139 microRNA 139 decreases expression ISO icariin results in decreased expression of MIR139 mRNA CTD PMID:30533443 NCBI chr 1:155,878,828...155,878,895
Ensembl chr 1:155,878,825...155,878,902 		JBrowse link
G Mir140 microRNA 140 decreases expression ISO icariin results in decreased expression of MIR140 mRNA CTD PMID:30533443 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir146b microRNA 146b increases expression ISO icariin results in increased expression of MIR146B mRNA CTD PMID:30533443 NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525 		JBrowse link
G Mir150 microRNA 150 decreases expression ISO icariin results in decreased expression of MIR150 mRNA CTD PMID:30533443 NCBI chr 1:95,605,024...95,605,108
Ensembl chr 1:95,605,024...95,605,108 		JBrowse link
G Mir183 microRNA 183 increases expression ISO icariin results in increased expression of MIR183 mRNA CTD PMID:30533443 NCBI chr 4:58,788,614...58,788,723
Ensembl chr 4:58,788,614...58,788,723 		JBrowse link
G Mir200a microRNA 200a increases expression ISO icariin results in increased expression of MIR200A mRNA CTD PMID:30533443 NCBI chr 5:166,648,494...166,648,582 JBrowse link
G Mir200b microRNA 200b increases expression ISO icariin results in increased expression of MIR200B mRNA CTD PMID:30533443 NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366 		JBrowse link
G Mir205 microRNA 205 increases expression ISO icariin results in increased expression of MIR205 mRNA CTD PMID:30533443 NCBI chr13:105,035,878...105,035,985
Ensembl chr13:105,035,878...105,035,985 		JBrowse link
G Mir21 microRNA 21 increases expression ISO icariin results in increased expression of MIR21A mRNA CTD PMID:30533443 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir223 microRNA 223 decreases expression ISO icariin results in decreased expression of MIR223 mRNA CTD PMID:35532261 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mir30e microRNA 30e increases expression ISO icariin results in increased expression of MIR30E mRNA CTD PMID:30533443 NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:134,352,232...134,352,323 		JBrowse link
G Mir3545 microRNA 3545 increases expression ISO icariin results in increased expression of MIR203 mRNA CTD PMID:30533443 NCBI chr 6:131,199,542...131,199,656
Ensembl chr 6:131,199,542...131,199,656 		JBrowse link
G Mir429 microRNA 429 increases expression ISO icariin results in increased expression of MIR429 mRNA CTD PMID:30533443 NCBI chr 5:166,647,459...166,647,543
Ensembl chr 5:166,647,459...166,647,543 		JBrowse link
G Mir455 microRNA 455 decreases expression ISO icariin results in decreased expression of MIR455 mRNA CTD PMID:30533443 NCBI chr 5:76,689,313...76,689,390
Ensembl chr 5:76,689,313...76,689,390 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] affects the secretion of MMP9 protein CTD PMID:32344236 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions EXP [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of and results in decreased phosphorylation of MTOR protein; [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of MTOR mRNA CTD PMID:32344236 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions EXP [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of MUC5AC mRNA; [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased secretion of MUC5AC protein CTD PMID:32344236 NCBI chr 1:196,864,375...196,896,475
Ensembl chr 1:196,864,336...196,896,475 		JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming multiple interactions EXP [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased expression of MUC5B mRNA CTD PMID:32344236 NCBI chr 1:196,916,861...196,948,830
Ensembl chr 1:196,916,825...196,949,250 		JBrowse link
G Myh6 myosin heavy chain 6 increases expression ISO icariin results in increased expression of MYH6 mRNA CTD PMID:15780198 PMID:16490167 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720 		JBrowse link
G Myl2 myosin light chain 2 increases expression ISO icariin results in increased expression of MYL2 mRNA CTD PMID:15780198 PMID:16490167 NCBI chr12:34,454,223...34,468,554
Ensembl chr12:34,454,218...34,468,983 		JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 increases expression ISO icariin results in increased expression of NFE2L1 mRNA; icariin results in increased expression of NFE2L1 protein CTD PMID:17883938 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO icariin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; icariin results in increased phosphorylation of and results in increased degradation of NFKBIA protein; SB 203580 inhibits the reaction [icariin results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; U 0126 inhibits the reaction [icariin results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:18423597 PMID:20686223 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nkx2-5 NK2 homeobox 5 increases expression ISO icariin results in increased expression of NKX2-5 mRNA CTD PMID:16490167 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression ISO icariin results in increased expression of NLRP3 mRNA; icariin results in increased expression of NLRP3 protein CTD PMID:35532261 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nog noggin multiple interactions ISO NOG protein inhibits the reaction [icariin results in decreased expression of TNFSF11 mRNA]; NOG protein inhibits the reaction [icariin results in increased expression of BGLAP mRNA]; NOG protein inhibits the reaction [icariin results in increased expression of BMP2 mRNA]; NOG protein inhibits the reaction [icariin results in increased expression of RUNX2 mRNA]; NOG protein inhibits the reaction [icariin results in increased expression of SMAD4 mRNA]; NOG protein inhibits the reaction [icariin results in increased expression of SPP1 mRNA]; NOG protein inhibits the reaction [icariin results in increased expression of TNFRSF11B mRNA] CTD PMID:18295595 PMID:19747809 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Nos1 nitric oxide synthase 1 increases expression EXP icariin results in increased expression of NOS1 mRNA CTD PMID:16281085 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions		 EXP
ISO		 icariin results in increased expression of NOS2 mRNA; icariin results in increased expression of NOS2 protein
icariin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; icariin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]		 CTD PMID:15329286 PMID:16281085 PMID:20686223 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 increases expression
multiple interactions		 EXP
ISO		 icariin results in increased expression of NOS3 mRNA; icariin results in increased expression of NOS3 protein
icariin promotes the reaction [NOS3 protein results in increased chemical synthesis of Nitric Oxide]; icariin results in increased expression of and results in increased activity of NOS3 protein		 CTD PMID:15329286 PMID:17499557 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 multiple interactions
increases expression		 ISO icariin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of NR5A1 mRNA]; icariin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of NR5A1 protein]
icariin results in increased expression of NR5A1 mRNA; icariin results in increased expression of NR5A1 protein		 CTD PMID:31175881 PMID:35259346 NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328 		JBrowse link
G Pde5a phosphodiesterase 5A decreases expression
decreases activity		 EXP
ISO		 icariin results in decreased expression of PDE5A mRNA alternative form
icariin analog results in decreased activity of PDE5A protein; icariin results in decreased activity of PDE5A protein		 CTD PMID:17120748 PMID:18778098 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701 		JBrowse link
G Pgr progesterone receptor increases expression
multiple interactions		 ISO icariin results in increased expression of PGR mRNA
fulvestrant inhibits the reaction [icariin results in increased expression of PGR mRNA]		 CTD PMID:15541416 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression ISO icariin results in increased expression of PPARA mRNA; icariin results in increased expression of PPARA protein CTD PMID:17883938 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression
multiple interactions		 ISO
EXP		 icariin results in increased expression of PPARGC1A mRNA; icariin results in increased expression of PPARGC1A protein
Histone Deacetylase Inhibitors inhibits the reaction [icariin inhibits the reaction [Rotenone results in decreased expression of PPARGC1A protein]]; icariin inhibits the reaction [Rotenone results in decreased expression of PPARGC1A protein]		 CTD PMID:17883938 PMID:31251943 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO icariin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; icariin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:20686223 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases activity
multiple interactions		 ISO icariin results in increased activity of RELA protein
icariin inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]; icariin results in increased expression of and affects the localization of RELA protein; SB 203580 inhibits the reaction [icariin results in increased expression of and affects the localization of RELA protein]; U 0126 inhibits the reaction [icariin results in increased expression of and affects the localization of RELA protein]		 CTD PMID:17499557 PMID:18423597 PMID:20686223 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression
multiple interactions		 ISO
EXP		 icariin results in increased expression of RUNX2 mRNA
NOG protein inhibits the reaction [icariin results in increased expression of RUNX2 mRNA]		 CTD PMID:18295595 PMID:19747809 PMID:20019778 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Sirt1 sirtuin 1 increases expression
multiple interactions
affects expression		 ISO
EXP		 icariin results in increased expression of SIRT1 mRNA; icariin results in increased expression of SIRT1 protein
icariin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of SIRT1 mRNA]; icariin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of SIRT1 protein]; SB 203580 inhibits the reaction [icariin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of SIRT1 mRNA]]; SB 203580 inhibits the reaction [icariin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of SIRT1 protein]]
icariin affects the expression of SIRT1 mRNA; icariin affects the expression of SIRT1 protein
icariin inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in decreased expression of SIRT1 protein]; Niacinamide inhibits the reaction [icariin inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in decreased expression of SIRT1 protein]]		 CTD PMID:19303870 PMID:25472572 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt3 sirtuin 3 multiple interactions EXP Histone Deacetylase Inhibitors inhibits the reaction [icariin inhibits the reaction [Rotenone results in decreased expression of SIRT3 protein]]; icariin inhibits the reaction [Rotenone results in decreased expression of SIRT3 protein] CTD PMID:31251943 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions
decreases activity		 ISO [icariin results in decreased activity of SLCO1B3 protein] which results in decreased uptake of Sincalide CTD PMID:24265111 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981 		JBrowse link
G Smad4 SMAD family member 4 increases expression
multiple interactions		 ISO icariin results in increased expression of SMAD4 mRNA
NOG protein inhibits the reaction [icariin results in increased expression of SMAD4 mRNA]		 CTD PMID:19747809 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Smad6 SMAD family member 6 multiple interactions ISO SMAD6 protein inhibits the reaction [icariin results in increased expression of BGLAP mRNA]; SMAD6 protein inhibits the reaction [icariin results in increased expression of SPP1 mRNA] CTD PMID:18295595 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763 		JBrowse link
G Sod2 superoxide dismutase 2 affects expression
multiple interactions		 EXP
ISO		 icariin affects the expression of SOD2 protein
icariin inhibits the reaction [APP protein alternative form results in decreased expression of SOD2 mRNA]
icariin inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in decreased expression of SOD2 protein]		 CTD PMID:19782061 PMID:25472572 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions
increases expression		 ISO
EXP		 NOG protein inhibits the reaction [icariin results in increased expression of SPP1 mRNA]; SMAD6 protein inhibits the reaction [icariin results in increased expression of SPP1 mRNA] CTD PMID:16696327 PMID:18236786 PMID:18295595 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase increases phosphorylation
multiple interactions		 ISO icariin results in increased phosphorylation of SRC protein
afimoxifene inhibits the reaction [icariin results in increased phosphorylation of SRC protein]; icariin inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of SRC protein]		 CTD PMID:35259346 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Tff1 trefoil factor 1 increases expression
multiple interactions		 ISO icariin results in increased expression of TFF1 mRNA
fulvestrant inhibits the reaction [icariin results in increased expression of TFF1 mRNA]		 CTD PMID:15541416 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression EXP icariin results in increased expression of TGFB1 mRNA CTD PMID:18236786 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP icariin inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:31251943 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP [paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] affects the secretion of TIMP1 protein CTD PMID:32344236 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tnf tumor necrosis factor affects expression
multiple interactions		 EXP
ISO		 icariin affects the expression of TNF protein
[paeonol co-treated with icariin co-treated with nobiletin co-treated with Ginsenosides co-treated with astragaloside A] results in decreased secretion of TNF protein
icariin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; icariin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]		 CTD PMID:20686223 PMID:25472572 PMID:32344236 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B multiple interactions
increases expression		 ISO NOG protein inhibits the reaction [icariin results in increased expression of TNFRSF11B mRNA] CTD PMID:19747809 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538 		JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression
multiple interactions		 ISO icariin results in decreased expression of TNFSF11 mRNA
NOG protein inhibits the reaction [icariin results in decreased expression of TNFSF11 mRNA]		 CTD PMID:19747809 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO icariin results in increased expression of TRP53 mRNA; icariin results in increased expression of TRP53 protein CTD PMID:15878162 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
icariside II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression ISO baohuoside I results in decreased expression of ABCB11 mRNA; baohuoside I results in decreased expression of ABCB11 protein CTD PMID:35802278 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression ISO baohuoside I results in decreased expression of ABCC2 mRNA; baohuoside I results in decreased expression of ABCC2 protein CTD PMID:35802278 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation		 ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]
baohuoside I results in decreased phosphorylation of AKT1 protein		 CTD PMID:25119583 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt1s1 AKT1 substrate 1 multiple interactions
decreases phosphorylation		 ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein]
baohuoside I results in decreased phosphorylation of AKT1S1 protein		 CTD PMID:25119583 NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases expression
increases secretion		 EXP
ISO		 baohuoside I results in increased expression of ALPL mRNA
baohuoside I results in increased secretion of ALPL protein		 CTD PMID:17764702 PMID:35802278 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO baohuoside I results in increased expression of BAX protein CTD PMID:22687635 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO baohuoside I results in decreased expression of BCL2 protein CTD PMID:22687635 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression EXP baohuoside I results in increased expression of BGLAP mRNA CTD PMID:17764702 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase multiple interactions
decreases phosphorylation		 ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of BRAF protein]
baohuoside I results in decreased phosphorylation of BRAF protein		 CTD PMID:25119583 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage		 ISO baohuoside I results in increased activity of CASP3 protein
baohuoside I results in increased cleavage of CASP3 protein		 CTD PMID:19289254 PMID:22687635 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 increases activity ISO baohuoside I results in increased activity of CASP8 protein CTD PMID:19289254 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases cleavage
increases activity		 ISO baohuoside I results in increased cleavage of CASP9 protein
baohuoside I results in increased activity of CASP9 protein		 CTD PMID:19289254 PMID:22687635 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression EXP baohuoside I results in increased expression of COL1A2 mRNA CTD PMID:17764702 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression ISO baohuoside I results in increased expression of CYP7A1 mRNA; baohuoside I results in increased expression of CYP7A1 protein CTD PMID:35802278 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1S1 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of BRAF protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MTOR protein] CTD PMID:25119583 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
decreases phosphorylation		 ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]
baohuoside I results in decreased phosphorylation of EGFR protein		 CTD PMID:25119583 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO baohuoside I binds to and results in increased degradation of ESR1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [baohuoside I results in increased degradation of ESR1 protein]; ESR1 inhibits the reaction [baohuoside I results in decreased expression of and affects the localization of NR0B2 protein] CTD PMID:35802278 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases secretion ISO baohuoside I results in increased secretion of GOT1 protein CTD PMID:35802278 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases secretion ISO baohuoside I results in increased secretion of GPT protein CTD PMID:35802278 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation ISO baohuoside I results in decreased phosphorylation of GSK3B protein CTD PMID:25119583 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation		 ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]
baohuoside I results in decreased phosphorylation of MAPK1 protein		 CTD PMID:25119583 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation		 ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]
baohuoside I results in decreased phosphorylation of MAPK3 protein		 CTD PMID:25119583 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO baohuoside I results in decreased expression of MKI67 protein CTD PMID:25119583 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
decreases phosphorylation		 ISO baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of MTOR protein]
baohuoside I results in decreased phosphorylation of MTOR protein		 CTD PMID:25119583 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression ISO baohuoside I results in decreased expression of NOS2 CTD PMID:19289254 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression
multiple interactions		 ISO baohuoside I results in decreased expression of NR0B2 mRNA; baohuoside I results in decreased expression of NR0B2 protein
baohuoside I results in decreased expression of and results in decreased activity of and affects the localization of NR0B2 protein; ESR1 inhibits the reaction [baohuoside I results in decreased expression of and affects the localization of NR0B2 protein]		 CTD PMID:35802278 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression ISO baohuoside I results in decreased expression of NR1H4 mRNA; baohuoside I results in decreased expression of NR1H4 protein CTD PMID:35802278 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage		 ISO Dinoprostone inhibits the reaction [baohuoside I results in increased cleavage of PARP1 protein]; PTGS2 mutant form promotes the reaction [baohuoside I results in increased cleavage of PARP1 protein] CTD PMID:19289254 PMID:22687635 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 decreases phosphorylation ISO baohuoside I results in decreased phosphorylation of PDPK1 protein CTD PMID:25119583 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions		 ISO baohuoside I results in decreased expression of PTGS2
[baohuoside I results in decreased expression of PTGS2] which results in decreased abundance of Dinoprostone; PTGS2 mutant form promotes the reaction [baohuoside I results in increased cleavage of PARP1 protein]		 CTD PMID:19289254 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 increases expression ISO baohuoside I results in increased expression of SLC10A1 protein
baohuoside I results in increased expression of SLC10A1 mRNA; baohuoside I results in increased expression of SLC10A1 protein		 CTD PMID:35802278 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670 		JBrowse link
G Slco1c1 solute carrier organic anion transporter family, member 1c1 decreases expression ISO baohuoside I results in decreased expression of SLCO1A1 mRNA CTD PMID:35802278 NCBI chr 4:174,466,621...174,513,290
Ensembl chr 4:174,466,631...174,513,289 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B increases expression EXP baohuoside I results in increased expression of TNFRSF11B mRNA CTD PMID:17764702 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538 		JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression EXP baohuoside I results in decreased expression of TNFSF11 mRNA CTD PMID:17764702 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO baohuoside I results in decreased expression of VEGFA CTD PMID:19289254 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
kaempferol 3-O-beta-D-galactoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g2a phospholipase A2 group IIA affects activity ISO kaempferol-3-O-galactoside affects the activity of PLA2G2A protein CTD PMID:8190018 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014 		JBrowse link
kaempferol 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of APP protein] CTD PMID:35537655 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Cat catalase multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of CAT protein] CTD PMID:35537655 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA] CTD PMID:22210036 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL3 mRNA] CTD PMID:22210036 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of HES1 protein] CTD PMID:35537655 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in decreased expression of IL10 protein] CTD PMID:35537655 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of IL1B protein]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:22210036 PMID:35537655 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of IL6 protein]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:22210036 PMID:35537655 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO astragalin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:22210036 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:22210036 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Notch1 notch receptor 1 multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of NOTCH1 protein] CTD PMID:35537655 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:22210036 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of RBPJ protein] CTD PMID:35537655 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of and results in increased phosphorylation of RELA protein]; astragalin inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] CTD PMID:22210036 PMID:35537655 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of TNF protein]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] CTD PMID:22210036 PMID:35537655 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
luteolin 7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation		 ISO [luteolin-7-glucoside co-treated with Hydrogen Peroxide] results in increased phosphorylation of AKT1 protein
luteolin-7-glucoside results in decreased phosphorylation of AKT1 protein		 CTD PMID:31157476 PMID:34165247 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO luteolin-7-glucoside results in increased expression of BAX protein CTD PMID:34165247 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression		 ISO luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]; luteolin-7-glucoside inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]
luteolin-7-glucoside results in decreased expression of BCL2 protein		 CTD PMID:31157476 PMID:31381935 PMID:34165247 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO luteolin-7-glucoside results in decreased expression of BCL2L1 protein CTD PMID:34165247 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO luteolin-7-glucoside results in increased expression of BID protein alternative form CTD PMID:34165247 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage		 ISO benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [luteolin-7-glucoside results in increased cleavage of CASP3 protein]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP3 protein modified form]; luteolin-7-glucoside inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP3 protein] CTD PMID:31157476 PMID:31381935 PMID:34165247 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 increases cleavage ISO luteolin-7-glucoside results in increased cleavage of CASP8 protein CTD PMID:34165247 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases cleavage ISO luteolin-7-glucoside results in increased cleavage of CASP9 protein CTD PMID:34165247 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions ISO luteolin-7-glucoside inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein] CTD PMID:31157476 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO luteolin-7-glucoside results in decreased expression of CCNA2 protein CTD PMID:34165247 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO luteolin-7-glucoside results in decreased expression of CCNB1 protein CTD PMID:34165247 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases phosphorylation ISO luteolin-7-glucoside results in decreased phosphorylation of CDK1 protein CTD PMID:34165247 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO luteolin-7-glucoside results in decreased expression of CDK2 protein CTD PMID:34165247 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO luteolin-7-glucoside results in increased expression of CDKN1A protein CTD PMID:34165247 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Esr1 estrogen receptor 1 increases activity
multiple interactions		 ISO luteolin-7-glucoside results in increased activity of ESR1 protein
1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR1 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR1 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR1 protein]		 CTD PMID:31381935 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases activity		 ISO 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR2 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR2 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR2 protein]
luteolin-7-glucoside results in increased activity of ESR2 protein		 CTD PMID:31381935 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO luteolin-7-glucoside results in increased expression of FAS protein CTD PMID:34165247 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of FOS protein]]; 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of FOS protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of FOS protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of FOS protein] CTD PMID:31381935 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO luteolin-7-glucoside inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 protein] CTD PMID:11123379 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation
multiple interactions		 ISO luteolin-7-glucoside results in decreased phosphorylation of MAPK1 protein
1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]]; 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]		 CTD PMID:31381935 PMID:34165247 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation		 ISO 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]]; 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]
luteolin-7-glucoside results in decreased phosphorylation of MAPK3 protein		 CTD PMID:31381935 PMID:34165247 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions		 ISO luteolin-7-glucoside results in increased cleavage of PARP1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein]; pyrazolanthrone inhibits the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein]; SB 203580 promotes the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein]; U 0126 inhibits the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein]		 CTD PMID:34165247 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 increases expression ISO luteolin-7-glucoside results in increased expression of RIPK1 protein CTD PMID:34165247 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of STAT3 protein]]; 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of STAT3 protein]]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of STAT3 protein]]; luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of STAT3 protein] CTD PMID:31381935 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO luteolin-7-glucoside inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF protein] CTD PMID:11123379 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression ISO luteolin-7-glucoside results in increased expression of TNFRSF1A protein CTD PMID:34165247 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
miquelianin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadm acyl-CoA dehydrogenase medium chain multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA] CTD PMID:26190035 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147 		JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine binds to ADRB2 protein] CTD PMID:24929186 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Agt angiotensinogen multiple interactions ISO quercetin 3-O-glucuronide analog inhibits the reaction [AGT protein results in increased phosphorylation of JUN protein] CTD PMID:12054679 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [ALOX5 protein results in increased chemical synthesis of Leukotriene B4] CTD PMID:18096136 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G App amyloid beta precursor protein decreases expression
multiple interactions		 ISO quercetin 3-O-glucuronide results in decreased expression of APP protein
quercetin 3-O-glucuronide inhibits the reaction [APP protein binds to APP protein modified form]		 CTD PMID:23097297 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Cat catalase multiple interactions EXP [quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of CAT mRNA; [quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of CAT protein CTD PMID:25716194 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav1 caveolin 1 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Lysophosphatidylcholines results in increased expression of CAV1 mRNA] CTD PMID:27257344 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cd36 CD36 molecule decreases expression ISO quercetin 3-O-glucuronide results in decreased expression of CD36 mRNA CTD PMID:18199750 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA] CTD PMID:26190035 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS mRNA]; quercetin 3-O-glucuronide inhibits the reaction [Dietary Fats results in increased expression of FAS mRNA] CTD PMID:26190035 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP [quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of GCLC mRNA; [quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of GCLC protein CTD PMID:25716194 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO
EXP		 quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine results in increased expression of HMOX1 mRNA]
[quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of HMOX1 mRNA; [quercetin 3-O-glucuronide co-treated with 3-methylquercetin co-treated with Quercetin] results in increased expression of HMOX1 protein		 CTD PMID:24929186 PMID:25716194 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Lysophosphatidylcholines results in increased expression of ICAM1 mRNA] CTD PMID:27257344 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Palmitates results in increased phosphorylation of IKBKB protein] CTD PMID:23504962 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein] CTD PMID:26190035 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Palmitates results in increased secretion of IL6 protein] CTD PMID:23504962 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Palmitates inhibits the reaction [INS protein results in increased chemical synthesis of Nitric Oxide]]; quercetin 3-O-glucuronide inhibits the reaction [Palmitates inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]]; quercetin 3-O-glucuronide inhibits the reaction [Palmitates inhibits the reaction [INS protein results in increased phosphorylation of NOS3 protein]] CTD PMID:23504962 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Palmitates inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]]; quercetin 3-O-glucuronide inhibits the reaction [Palmitates results in increased phosphorylation of IRS1 protein] CTD PMID:23504962 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO quercetin 3-O-glucuronide analog inhibits the reaction [AGT protein results in increased phosphorylation of JUN protein] CTD PMID:12054679 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine results in increased expression of MMP2 mRNA] CTD PMID:24929186 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine results in increased activity of MMP9 protein]; quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine results in increased expression of MMP9 mRNA] CTD PMID:24929186 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Msr1 macrophage scavenger receptor 1 decreases expression ISO quercetin 3-O-glucuronide results in decreased expression of MSR1 mRNA CTD PMID:18199750 NCBI chr16:52,717,775...52,802,890
Ensembl chr16:52,717,732...52,799,676 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein] CTD PMID:27257013 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Palmitates inhibits the reaction [INS protein results in increased phosphorylation of NOS3 protein]] CTD PMID:23504962 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein]; quercetin 3-O-glucuronide inhibits the reaction [Dietary Fats results in decreased expression of PPARA protein] CTD PMID:26190035 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO quercetin 3-O-glucuronide results in increased expression of PPARG mRNA CTD PMID:25765892 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein] CTD PMID:27257013 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [Palmitates results in increased phosphorylation of RELA protein] CTD PMID:23504962 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases uptake
multiple interactions		 ISO SLC22A8 protein results in increased uptake of quercetin 3-O-glucuronide analog
quercetin 3-O-glucuronide analog inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein]; quercetin 3-O-glucuronide inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein]		 CTD PMID:21244849 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions EXP quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA]; quercetin 3-O-glucuronide inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:26190035 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO		 quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]
quercetin 3-O-glucuronide inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with TNF protein] results in increased expression of VCAM1 protein]; quercetin 3-O-glucuronide inhibits the reaction [Palmitates results in increased secretion of TNF protein]		 CTD PMID:17880982 PMID:23504962 PMID:26190035 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases activity ISO quercetin 3-O-glucuronide results in decreased activity of TNFSF11 protein CTD PMID:19495926 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO quercetin 3-O-glucuronide inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with TNF protein] results in increased expression of VCAM1 protein] CTD PMID:17880982 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
myricitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:25656916 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ALPL mRNA] CTD PMID:25130202 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Apoe apolipoprotein E multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in decreased activity of CAT protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased activity of CASP3 protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CCL2 protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CRP protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of ICAM1 protein] CTD PMID:23639522 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein] CTD PMID:23639522 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:23639522 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BGLAP mRNA] CTD PMID:25130202 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]
myricitrin inhibits the reaction [APOE gene mutant form results in increased activity of CASP3 protein]		 CTD PMID:23639522 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in decreased activity of CAT protein]
myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein]		 CTD PMID:23639522 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CCL2 protein] CTD PMID:23639522 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of COL1A1 mRNA] CTD PMID:25130202 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Crp C-reactive protein multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CRP protein] CTD PMID:23639522 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein] CTD PMID:25656916 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein] CTD PMID:25656916 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of GPX1 protein] CTD PMID:23639522 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of ICAM1 protein] CTD PMID:23639522 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of IL6 protein] CTD PMID:25130202 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] CTD PMID:23639522 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein] CTD PMID:23639522 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:23639522 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of NOS3 protein] CTD PMID:23639522 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO myricitrin promotes the reaction [Carbon Tetrachloride results in increased expression of PCNA protein] CTD PMID:25656916 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of PPARG mRNA] CTD PMID:25130202 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein] CTD PMID:25656916 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein] CTD PMID:25656916 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein] CTD PMID:25656916 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFSF11 protein] CTD PMID:25130202 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein] CTD PMID:23639522 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
quercetin 3-O-beta-D-galactopyranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
increases expression		 EXP hyperoside results in increased expression of and results in increased activity of ACHE protein
hyperoside results in increased expression of ACHE mRNA		 CTD PMID:27019979 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP		 hyperoside inhibits the reaction [tert-Butylhydroperoxide affects the localization of BAX protein]
hyperoside inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein]		 CTD PMID:18552516 PMID:31326407 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP hyperoside inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:31326407 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO [Quercetin co-treated with hyperoside] results in decreased expression of BIRC5 mRNA; [Quercetin co-treated with hyperoside] results in decreased expression of BIRC5 protein CTD PMID:24173369 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Quercetin co-treated with hyperoside] results in increased cleavage of CASP3 protein CTD PMID:24173369 PMID:25354548 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase multiple interactions EXP cyclopamine inhibits the reaction [hyperoside inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein]]; hyperoside inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein] CTD PMID:31326407 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO hyperoside inhibits the reaction [tert-Butylhydroperoxide affects the localization of CYCS protein] CTD PMID:18552516 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity
multiple interactions		 ISO hyperoside results in decreased activity of CYP2E1 protein
hyperoside inhibits the reaction [Acetaminophen results in decreased activity of CYP2E1 protein]		 CTD PMID:26772156 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO hyperoside inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:22613215 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Gli1 GLI family zinc finger 1 multiple interactions
increases expression		 EXP hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of GLI1 mRNA]; hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of GLI1 protein]
hyperoside results in increased expression of GLI1 mRNA; hyperoside results in increased expression of GLI1 protein		 CTD PMID:31326407 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO hyperoside inhibits the reaction [Acetaminophen results in increased activity of GPT protein] CTD PMID:26772156 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein] CTD PMID:30125551 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:30125551 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mir21 microRNA 21 multiple interactions ISO [Quercetin co-treated with hyperoside] results in decreased expression of MIR21 mRNA; MIR21 mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of PDCD4 mRNA]; MIR21 mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of PDCD4 protein]; MIR21 mRNA results in decreased susceptibility to [Quercetin co-treated with hyperoside] CTD PMID:25354548 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir27a microRNA 27a multiple interactions ISO [Quercetin co-treated with hyperoside] inhibits the reaction [MIR27A mRNA results in decreased expression of ZBTB10 mRNA]; [Quercetin co-treated with hyperoside] inhibits the reaction [MIR27A mRNA results in increased expression of SP1 mRNA]; [Quercetin co-treated with hyperoside] results in decreased expression of MIR27A mRNA; MIR27A mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of ZBTB10 mRNA] CTD PMID:24173369 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects localization ISO hyperoside affects the localization of NFE2L2 protein CTD PMID:26772156 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:30125551 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP Hyperoside increases expression of Nqo1 protein in liver RGD PMID:31399183 RGD:25823190 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [Quercetin co-treated with hyperoside] results in increased cleavage of PARP1 protein CTD PMID:24173369 PMID:25354548 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pdcd4 programmed cell death 4 multiple interactions ISO [Quercetin co-treated with hyperoside] results in increased expression of PDCD4 mRNA; [Quercetin co-treated with hyperoside] results in increased expression of PDCD4 protein; MIR21 mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of PDCD4 mRNA]; MIR21 mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of PDCD4 protein] CTD PMID:25354548 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275 		JBrowse link
G Prima1 proline rich membrane anchor 1 increases expression EXP hyperoside results in increased expression of PRIMA1 mRNA CTD PMID:27019979 NCBI chr 6:122,338,365...122,390,955
Ensembl chr 6:122,338,370...122,389,921 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein] CTD PMID:30125551 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Shh sonic hedgehog signaling molecule increases expression
multiple interactions		 EXP hyperoside results in increased expression of SHH mRNA; hyperoside results in increased expression of SHH protein
hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of SHH mRNA]; hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of SHH protein]		 CTD PMID:31326407 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO hyperoside inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of SIRT1 protein] CTD PMID:18552516 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 increases expression ISO hyperoside analog results in increased expression of SLC2A2 mRNA CTD PMID:33493636 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933 		JBrowse link
G Slc5a1 solute carrier family 5 member 1 increases expression ISO hyperoside analog results in increased expression of SLC5A1 mRNA CTD PMID:33493636 NCBI chr14:77,553,990...77,618,589
Ensembl chr14:77,553,843...77,618,547 		JBrowse link
G Smo smoothened, frizzled class receptor multiple interactions
increases expression		 EXP hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of SMO mRNA]; hyperoside promotes the reaction [Hydrogen Peroxide results in increased expression of SMO protein]
hyperoside results in increased expression of SMO mRNA; hyperoside results in increased expression of SMO protein		 CTD PMID:31326407 NCBI chr 4:58,344,101...58,372,828
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO [Quercetin co-treated with hyperoside] inhibits the reaction [MIR27A mRNA results in increased expression of SP1 mRNA]; [Quercetin co-treated with hyperoside] results in decreased expression of SP1 mRNA; [Quercetin co-treated with hyperoside] results in decreased expression of SP1 protein CTD PMID:24173369 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961 		JBrowse link
G Sp3 Sp3 transcription factor multiple interactions ISO [Quercetin co-treated with hyperoside] results in decreased expression of SP3 mRNA; [Quercetin co-treated with hyperoside] results in decreased expression of SP3 protein CTD PMID:24173369 NCBI chr 3:57,811,855...57,857,150
Ensembl chr 3:57,812,075...57,860,342 		JBrowse link
G Sp4 Sp4 transcription factor multiple interactions ISO [Quercetin co-treated with hyperoside] results in decreased expression of SP4 mRNA; [Quercetin co-treated with hyperoside] results in decreased expression of SP4 protein CTD PMID:24173369 NCBI chr 6:139,187,458...139,252,741
Ensembl chr 6:139,192,147...139,252,126 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 multiple interactions
increases expression		 ISO hyperoside inhibits the reaction [Acetaminophen results in decreased expression of SULT2A1 mRNA]
hyperoside results in increased expression of SULT2A1 mRNA		 CTD PMID:26772156 NCBI chr 1:75,451,178...75,508,142
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased expression of TNFRSF1A protein]; hyperoside inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; hyperoside inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; hyperoside inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein] CTD PMID:30125551 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased expression of TNFRSF1A protein] CTD PMID:30125551 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions
increases expression		 ISO hyperoside inhibits the reaction [Acetaminophen results in decreased expression of UGT1A1 mRNA]
hyperoside results in increased expression of UGT1A1 mRNA		 CTD PMID:26772156 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 multiple interactions ISO hyperoside inhibits the reaction [Acetaminophen results in decreased expression of UGT1A6 mRNA] CTD PMID:26772156 NCBI chr 9:88,747,229...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 multiple interactions
increases expression		 ISO hyperoside inhibits the reaction [Acetaminophen results in decreased expression of UGT2B1 mRNA]
hyperoside results in increased expression of UGT2B1 mRNA		 CTD PMID:26772156 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO hyperoside inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; hyperoside inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:30125551 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Zbtb10 zinc finger and BTB domain containing 10 multiple interactions ISO [Quercetin co-treated with hyperoside] inhibits the reaction [MIR27A mRNA results in decreased expression of ZBTB10 mRNA]; [Quercetin co-treated with hyperoside] results in increased expression of ZBTB10 mRNA; MIR27A mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of ZBTB10 mRNA] CTD PMID:24173369 NCBI chr 2:92,475,254...92,509,857
Ensembl chr 2:92,479,014...92,512,515 		JBrowse link
quercetin 3-O-beta-D-glucofuranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat2 acetyl-CoA acetyltransferase 2 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of ACAT2 mRNA CTD PMID:18032389 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of AKR7A3 mRNA CTD PMID:20033131 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394 		JBrowse link
G Apoa1 apolipoprotein A1 increases secretion ISO isoquercitrin results in increased secretion of APOA1 protein CTD PMID:24963805 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Atf6 activating transcription factor 6 increases expression EXP isoquercitrin results in increased expression of ATF6 mRNA CTD PMID:30365939 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atxn2 ataxin 2 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN2 mRNA] CTD PMID:25129099 NCBI chr12:34,754,132...34,851,175
Ensembl chr12:34,754,137...34,851,479 		JBrowse link
G Atxn3 ataxin 3 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN3 mRNA] CTD PMID:25129099 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO isoquercitrin results in decreased expression of BCL2 mRNA CTD PMID:30597948 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 affects expression ISO isoquercitrin affects the expression of CASP3 mRNA CTD PMID:30597948 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 decreases expression ISO isoquercitrin results in decreased expression of CASP8 mRNA CTD PMID:30597948 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cat catalase multiple interactions EXP [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of CAT mRNA; isoquercitrin inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:30298849 PMID:30817903 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCL2 mRNA] CTD PMID:21295105 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions EXP isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CCL5 protein] CTD PMID:14654164 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDKN2B mRNA] CTD PMID:21295105 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050 		JBrowse link
G Ctnnb1 catenin beta 1 affects expression ISO isoquercitrin affects the expression of CTNNB1 mRNA CTD PMID:30597948 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions EXP isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CXCL2 protein] CTD PMID:14654164 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases activity		 EXP
ISO		 [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A1 mRNA
isoquercitrin results in decreased activity of CYP1A1 protein		 CTD PMID:16271822 PMID:20033131 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A2 mRNA CTD PMID:20033131 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO isoquercitrin results in decreased activity of CYP1B1 protein CTD PMID:16271822 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP2B2 mRNA] CTD PMID:20033131 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp51 cytochrome P450, family 51 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of CYP51A1 mRNA CTD PMID:18032389 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of DHCR7 mRNA CTD PMID:18032389 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:26109002 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of EGLN1 mRNA] CTD PMID:25129099 NCBI chr19:52,867,914...52,907,169
Ensembl chr19:52,869,486...52,907,777 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDFT1 mRNA CTD PMID:18032389 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fdps farnesyl diphosphate synthase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDPS mRNA CTD PMID:18032389 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of FOS mRNA CTD PMID:31068541 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GPX2 mRNA CTD PMID:20033131 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 multiple interactions EXP isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of GRIA3 mRNA] CTD PMID:31068541 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 multiple interactions EXP [isoquercitrin co-treated with oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTA5 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCR mRNA CTD PMID:18032389 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCS1 mRNA CTD PMID:18032389 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP isoquercitrin inhibits the reaction [beta-Naphthoflavone results in increased expression of HMOX1 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA] CTD PMID:21295105 PMID:30817903 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Ibsp integrin-binding sialoprotein increases expression EXP isoquercitrin results in increased expression of IBSP mRNA CTD PMID:30365939 NCBI chr14:5,439,825...5,452,570
Ensembl chr14:5,439,829...5,452,693 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP [isoquercitrin analog co-treated with Propylthiouracil] results in increased expression of IL1A mRNA; [isoquercitrin co-treated with Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL1A mRNA CTD PMID:21295105 PMID:31068541 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA] CTD PMID:30817903 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA] CTD PMID:30817903 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Insig1 insulin induced gene 1 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of INSIG1 mRNA CTD PMID:18032389 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Jak1 Janus kinase 1 increases expression ISO isoquercitrin results in increased expression of JAK1 mRNA CTD PMID:30597948 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Jak2 Janus kinase 2 increases expression ISO isoquercitrin results in increased expression of JAK2 mRNA CTD PMID:30597948 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA] CTD PMID:30817903 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Lct lactase multiple interactions EXP [migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of isoquercitrin CTD PMID:12663055 NCBI chr13:39,781,929...39,824,456
Ensembl chr13:39,781,929...39,824,456 		JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of LDLR mRNA CTD PMID:18032389 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein] CTD PMID:26109002 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:26109002 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member affects expression ISO isoquercitrin affects the expression of MCL1 mRNA CTD PMID:30597948 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Me1 malic enzyme 1 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNA] CTD PMID:20033131 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO isoquercitrin results in decreased expression of and results in decreased activity of MMP2 protein CTD PMID:18715546 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO isoquercitrin results in decreased expression of and results in decreased activity of MMP9 protein CTD PMID:18715546 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA] CTD PMID:30817903 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of NFKB1 mRNA CTD PMID:31068541 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NFKBIA mRNA] CTD PMID:20045035 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NOS2 mRNA] CTD PMID:21295105 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of NQO1 mRNA; isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of NQO1 mRNA] CTD PMID:20033131 PMID:31068541 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions EXP [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of NR3C2 mRNA CTD PMID:30298849 NCBI chr19:30,715,648...31,059,885
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSF mRNA] CTD PMID:25129099 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386 		JBrowse link
G Nsg1 neuronal vesicle trafficking associated 1 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSG1 mRNA] CTD PMID:25129099 NCBI chr14:72,648,771...72,670,521
Ensembl chr14:72,648,741...72,670,514 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of OPA1 mRNA] CTD PMID:25129099 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Otx2 orthodenticle homeobox 2 multiple interactions EXP isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of OTX2 mRNA] CTD PMID:31068541 NCBI chr15:21,942,233...21,953,034
Ensembl chr15:21,943,191...21,953,416 		JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PARK7 mRNA] CTD PMID:25129099 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha affects expression ISO isoquercitrin affects the expression of PIK3CA mRNA CTD PMID:30597948 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO isoquercitrin results in increased expression of PIK3R1 mRNA CTD PMID:30597948 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Ppid peptidylprolyl isomerase D multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PPID mRNA] CTD PMID:25129099 NCBI chr 2:164,727,803...164,740,168
Ensembl chr 2:164,727,779...164,740,221 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] CTD PMID:25129099 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA] CTD PMID:14654164 PMID:20045035 PMID:30817903 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit increases expression ISO isoquercitrin results in increased expression of RELB mRNA CTD PMID:30597948 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507 		JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression EXP isoquercitrin results in increased expression of RUNX2 mRNA CTD PMID:30365939 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Sc5d sterol-C5-desaturase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SC5D mRNA CTD PMID:18032389 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA] CTD PMID:20045035 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Slc5a1 solute carrier family 5 member 1 multiple interactions ISO isoquercitrin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside] CTD PMID:17495124 NCBI chr14:77,553,990...77,618,589
Ensembl chr14:77,553,843...77,618,547 		JBrowse link
G Sqle squalene epoxidase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SQLE mRNA CTD PMID:18032389 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased cleavage of and results in increased activity of SREBF2 protein; [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SREBF2 mRNA; SREBF2 protein affects the susceptibility to [isoquercitrin co-treated with Hydrogen Peroxide] CTD PMID:18032389 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression ISO isoquercitrin results in increased expression of STAT3 mRNA CTD PMID:30597948 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 increases expression ISO isoquercitrin results in increased expression of STAT6 mRNA CTD PMID:30597948 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of STUB1 mRNA] CTD PMID:25129099 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP isoquercitrin promotes the reaction [Oxidopamine results in decreased expression of TH mRNA] CTD PMID:25129099 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO isoquercitrin results in increased expression of TIMP1 protein CTD PMID:18715546 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNF mRNA]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] CTD PMID:14654164 PMID:21295105 PMID:30817903 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF1A protein] CTD PMID:21295105 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA] CTD PMID:30817903 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tradd TNFRSF1A-associated via death domain multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TRADD protein] CTD PMID:21295105 NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638 		JBrowse link
G Txn1 thioredoxin 1 multiple interactions EXP isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of TXN1 mRNA] CTD PMID:31068541 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Tyk2 tyrosine kinase 2 affects expression ISO isoquercitrin affects the expression of TYK2 mRNA CTD PMID:30597948 NCBI chr 8:19,641,881...19,667,157
Ensembl chr 8:19,641,884...19,667,044 		JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of UCHL1 mRNA] CTD PMID:25129099 NCBI chr14:41,485,033...41,495,590
Ensembl chr14:41,485,031...41,495,590 		JBrowse link
quercetin 3-O-beta-D-glucopyranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat2 acetyl-CoA acetyltransferase 2 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of ACAT2 mRNA CTD PMID:18032389 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of AKR7A3 mRNA CTD PMID:20033131 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394 		JBrowse link
G Apoa1 apolipoprotein A1 increases secretion ISO isoquercitrin results in increased secretion of APOA1 protein CTD PMID:24963805 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Atf6 activating transcription factor 6 increases expression EXP isoquercitrin results in increased expression of ATF6 mRNA CTD PMID:30365939 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atxn2 ataxin 2 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN2 mRNA] CTD PMID:25129099 NCBI chr12:34,754,132...34,851,175
Ensembl chr12:34,754,137...34,851,479 		JBrowse link
G Atxn3 ataxin 3 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of ATXN3 mRNA] CTD PMID:25129099 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO isoquercitrin results in decreased expression of BCL2 mRNA CTD PMID:30597948 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 affects expression ISO isoquercitrin affects the expression of CASP3 mRNA CTD PMID:30597948 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 decreases expression ISO isoquercitrin results in decreased expression of CASP8 mRNA CTD PMID:30597948 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cat catalase multiple interactions EXP [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of CAT mRNA; isoquercitrin inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:30298849 PMID:30817903 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCL2 mRNA] CTD PMID:21295105 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions EXP isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CCL5 protein] CTD PMID:14654164 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDKN2B mRNA] CTD PMID:21295105 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050 		JBrowse link
G Ctnnb1 catenin beta 1 affects expression ISO isoquercitrin affects the expression of CTNNB1 mRNA CTD PMID:30597948 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions EXP isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CXCL2 protein] CTD PMID:14654164 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
multiple interactions		 ISO
EXP		 isoquercitrin results in decreased activity of CYP1A1 protein
[Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A1 mRNA		 CTD PMID:16271822 PMID:20033131 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A2 mRNA CTD PMID:20033131 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO isoquercitrin results in decreased activity of CYP1B1 protein CTD PMID:16271822 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP2B2 mRNA] CTD PMID:20033131 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp51 cytochrome P450, family 51 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of CYP51A1 mRNA CTD PMID:18032389 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of DHCR7 mRNA CTD PMID:18032389 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:26109002 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of EGLN1 mRNA] CTD PMID:25129099 NCBI chr19:52,867,914...52,907,169
Ensembl chr19:52,869,486...52,907,777 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDFT1 mRNA CTD PMID:18032389 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fdps farnesyl diphosphate synthase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDPS mRNA CTD PMID:18032389 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of FOS mRNA CTD PMID:31068541 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GPX2 mRNA CTD PMID:20033131 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 multiple interactions EXP isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of GRIA3 mRNA] CTD PMID:31068541 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 multiple interactions EXP [isoquercitrin co-treated with oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTA5 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA] CTD PMID:20033131 PMID:20045035 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCR mRNA CTD PMID:18032389 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCS1 mRNA CTD PMID:18032389 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP isoquercitrin inhibits the reaction [beta-Naphthoflavone results in increased expression of HMOX1 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA] CTD PMID:21295105 PMID:30817903 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Ibsp integrin-binding sialoprotein increases expression EXP isoquercitrin results in increased expression of IBSP mRNA CTD PMID:30365939 NCBI chr14:5,439,825...5,452,570
Ensembl chr14:5,439,829...5,452,693 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP [isoquercitrin analog co-treated with Propylthiouracil] results in increased expression of IL1A mRNA; [isoquercitrin co-treated with Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL1A mRNA CTD PMID:21295105 PMID:31068541 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA] CTD PMID:30817903 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA] CTD PMID:30817903 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Insig1 insulin induced gene 1 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of INSIG1 mRNA CTD PMID:18032389 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Jak1 Janus kinase 1 increases expression ISO isoquercitrin results in increased expression of JAK1 mRNA CTD PMID:30597948 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Jak2 Janus kinase 2 increases expression ISO isoquercitrin results in increased expression of JAK2 mRNA CTD PMID:30597948 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA] CTD PMID:30817903 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Lct lactase multiple interactions EXP [migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of isoquercitrin CTD PMID:12663055 NCBI chr13:39,781,929...39,824,456
Ensembl chr13:39,781,929...39,824,456 		JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of LDLR mRNA CTD PMID:18032389 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein] CTD PMID:26109002 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:26109002 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member affects expression ISO isoquercitrin affects the expression of MCL1 mRNA CTD PMID:30597948 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Me1 malic enzyme 1 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNA] CTD PMID:20033131 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO isoquercitrin results in decreased expression of and results in decreased activity of MMP2 protein CTD PMID:18715546 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO isoquercitrin results in decreased expression of and results in decreased activity of MMP9 protein CTD PMID:18715546 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA] CTD PMID:30817903 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP [isoquercitrin analog co-treated with Propylthiouracil] results in decreased expression of NFKB1 mRNA CTD PMID:31068541 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NFKBIA mRNA] CTD PMID:20045035 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NOS2 mRNA] CTD PMID:21295105 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of NQO1 mRNA; isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of NQO1 mRNA] CTD PMID:20033131 PMID:31068541 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions EXP [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of NR3C2 mRNA CTD PMID:30298849 NCBI chr19:30,715,648...31,059,885
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSF mRNA] CTD PMID:25129099 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386 		JBrowse link
G Nsg1 neuronal vesicle trafficking associated 1 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of NSG1 mRNA] CTD PMID:25129099 NCBI chr14:72,648,771...72,670,521
Ensembl chr14:72,648,741...72,670,514 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in decreased expression of OPA1 mRNA] CTD PMID:25129099 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Otx2 orthodenticle homeobox 2 multiple interactions EXP isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of OTX2 mRNA] CTD PMID:31068541 NCBI chr15:21,942,233...21,953,034
Ensembl chr15:21,943,191...21,953,416 		JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PARK7 mRNA] CTD PMID:25129099 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha affects expression ISO isoquercitrin affects the expression of PIK3CA mRNA CTD PMID:30597948 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO isoquercitrin results in increased expression of PIK3R1 mRNA CTD PMID:30597948 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Ppid peptidylprolyl isomerase D multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PPID mRNA] CTD PMID:25129099 NCBI chr 2:164,727,803...164,740,168
Ensembl chr 2:164,727,779...164,740,221 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] CTD PMID:25129099 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA] CTD PMID:14654164 PMID:20045035 PMID:30817903 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of PTK2 protein] CTD PMID:26109002 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit increases expression ISO isoquercitrin results in increased expression of RELB mRNA CTD PMID:30597948 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507 		JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression EXP isoquercitrin results in increased expression of RUNX2 mRNA CTD PMID:30365939 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Sc5d sterol-C5-desaturase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SC5D mRNA CTD PMID:18032389 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA] CTD PMID:20045035 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Slc5a1 solute carrier family 5 member 1 multiple interactions ISO isoquercitrin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside] CTD PMID:17495124 NCBI chr14:77,553,990...77,618,589
Ensembl chr14:77,553,843...77,618,547 		JBrowse link
G Sqle squalene epoxidase multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SQLE mRNA CTD PMID:18032389 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO [isoquercitrin co-treated with Hydrogen Peroxide] results in increased cleavage of and results in increased activity of SREBF2 protein; [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of SREBF2 mRNA; SREBF2 protein affects the susceptibility to [isoquercitrin co-treated with Hydrogen Peroxide] CTD PMID:18032389 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression ISO isoquercitrin results in increased expression of STAT3 mRNA CTD PMID:30597948 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 increases expression ISO isoquercitrin results in increased expression of STAT6 mRNA CTD PMID:30597948 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of STUB1 mRNA] CTD PMID:25129099 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP isoquercitrin promotes the reaction [Oxidopamine results in decreased expression of TH mRNA] CTD PMID:25129099 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO isoquercitrin results in increased expression of TIMP1 protein CTD PMID:18715546 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNF mRNA]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] CTD PMID:14654164 PMID:21295105 PMID:30817903 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF1A protein] CTD PMID:21295105 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA] CTD PMID:30817903 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tradd TNFRSF1A-associated via death domain multiple interactions EXP isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TRADD protein] CTD PMID:21295105 NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638 		JBrowse link
G Txn1 thioredoxin 1 multiple interactions EXP isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of TXN1 mRNA] CTD PMID:31068541 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Tyk2 tyrosine kinase 2 affects expression ISO isoquercitrin affects the expression of TYK2 mRNA CTD PMID:30597948 NCBI chr 8:19,641,881...19,667,157
Ensembl chr 8:19,641,884...19,667,044 		JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions EXP isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of UCHL1 mRNA] CTD PMID:25129099 NCBI chr14:41,485,033...41,495,590
Ensembl chr14:41,485,031...41,495,590 		JBrowse link
quercetin 4'-O-beta-D-glucopyranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein] CTD PMID:32602595 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ap5m1 adaptor related protein complex 5 subunit mu 1 decreases expression ISO spiraeoside results in decreased expression of AP5M1 protein CTD PMID:34116102 NCBI chr15:22,355,478...22,385,222
Ensembl chr15:22,355,500...22,377,750 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in increased expression of BAX protein]]; spiraeoside inhibits the reaction [Glucose results in increased expression of BAX protein] CTD PMID:32602595 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of BCL2 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased expression of BCL2 protein]
spiraeoside results in decreased expression of BCL2 protein		 CTD PMID:32602595 PMID:34116102 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bid BH3 interacting domain death agonist decreases expression ISO spiraeoside results in decreased expression of BID protein CTD PMID:34116102 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Casp3 caspase 3 decreases expression ISO spiraeoside results in decreased expression of CASP3 protein CTD PMID:34116102 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 decreases expression ISO spiraeoside results in decreased expression of CASP9 protein CTD PMID:34116102 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in increased activity of CAT protein]]; spiraeoside inhibits the reaction [Glucose results in increased activity of CAT protein] CTD PMID:32602595 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO spiraeoside results in decreased expression of CDK2 protein CTD PMID:34116102 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cryz crystallin zeta increases activity ISO spiraeoside results in increased activity of CRYZ protein CTD PMID:8968052 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of HMOX1 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased expression of HMOX1 protein] CTD PMID:32602595 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Lct lactase multiple interactions EXP [migalastat results in decreased activity of LCT protein] which results in decreased hydrolysis of spiraeoside CTD PMID:12663055 NCBI chr13:39,781,929...39,824,456
Ensembl chr13:39,781,929...39,824,456 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein] CTD PMID:32602595 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Plcg2 phospholipase C, gamma 2 decreases phosphorylation ISO spiraeoside results in decreased phosphorylation of PLCG2 protein CTD PMID:15613018 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Slc5a1 solute carrier family 5 member 1 multiple interactions EXP
ISO		 [Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of spiraeoside
spiraeoside inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside]		 CTD PMID:12663055 PMID:17495124 NCBI chr14:77,553,990...77,618,589
Ensembl chr14:77,553,843...77,618,547 		JBrowse link
G Syk spleen associated tyrosine kinase decreases phosphorylation ISO spiraeoside results in decreased phosphorylation of SYK protein CTD PMID:15613018 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
quercitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO quercitrin promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]] CTD PMID:34217736 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 decreases expression ISO quercitrin results in decreased expression of ABCC4 mRNA CTD PMID:25193878 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Abcf2 ATP binding cassette subfamily F member 2 increases expression ISO quercitrin results in increased expression of ABCF2 mRNA CTD PMID:25193878 NCBI chr 4:10,594,802...10,607,606
Ensembl chr 4:10,594,907...10,607,606 		JBrowse link
G Acbd6 acyl-CoA binding domain containing 6 decreases expression ISO quercitrin results in decreased expression of ACBD6 mRNA CTD PMID:25193878 NCBI chr13:67,726,786...67,863,392
Ensembl chr13:67,726,786...67,862,311 		JBrowse link
G Acbd7 acyl-CoA binding domain containing 7 increases expression ISO quercitrin results in increased expression of ACBD7 mRNA CTD PMID:25193878 NCBI chr17:74,903,936...74,909,977
Ensembl chr17:74,903,177...74,905,811 		JBrowse link
G Actn1 actinin, alpha 1 affects expression ISO quercitrin affects the expression of ACTN1 mRNA CTD PMID:25193878 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251 		JBrowse link
G Actn4 actinin alpha 4 affects expression ISO quercitrin affects the expression of ACTN4 mRNA CTD PMID:25193878 NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847 		JBrowse link
G Adgrb1 adhesion G protein-coupled receptor B1 decreases expression ISO quercitrin results in decreased expression of ADGRB1 mRNA CTD PMID:25193878 NCBI chr 7:106,404,844...106,476,902
Ensembl chr 7:106,404,958...106,476,902 		JBrowse link
G Adgrf1 adhesion G protein-coupled receptor F1 decreases expression ISO quercitrin results in decreased expression of ADGRF1 mRNA CTD PMID:25193878 NCBI chr 9:17,661,258...17,696,359
Ensembl chr 9:17,660,930...17,711,704 		JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 decreases expression ISO quercitrin results in decreased expression of ADGRG1 mRNA CTD PMID:25193878 NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108 		JBrowse link
G Adgrg6 adhesion G protein-coupled receptor G6 decreases expression ISO quercitrin results in decreased expression of ADGRG6 mRNA CTD PMID:25193878 NCBI chr 1:8,812,889...8,954,239
Ensembl chr 1:8,812,904...8,954,123 		JBrowse link
G Adgrg7 adhesion G protein-coupled receptor G7 increases expression ISO quercitrin results in increased expression of ADGRG7 mRNA CTD PMID:25193878 NCBI chr11:43,808,101...43,877,539
Ensembl chr11:43,813,801...43,876,316 		JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 increases expression ISO quercitrin results in increased expression of ADGRV1 mRNA CTD PMID:25193878 NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688 		JBrowse link
G Adk adenosine kinase decreases expression ISO quercitrin results in decreased expression of ADK mRNA CTD PMID:25193878 NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510 		JBrowse link
G Adra2c adrenoceptor alpha 2C increases expression ISO quercitrin results in increased expression of ADRA2C mRNA CTD PMID:25193878 NCBI chr14:75,471,143...75,472,846
Ensembl chr14:75,471,143...75,472,846 		JBrowse link
G Ahnak2 AHNAK nucleoprotein 2 increases expression ISO quercitrin results in increased expression of AHNAK2 mRNA CTD PMID:25193878 NCBI chr 6:131,830,668...131,876,311 JBrowse link
G Alkbh7 alkB homolog 7 increases expression ISO quercitrin results in increased expression of ALKBH7 mRNA CTD PMID:25193878 NCBI chr 9:1,838,886...1,841,044
Ensembl chr 9:1,838,811...1,841,044 		JBrowse link
G Anapc15 anaphase promoting complex subunit 15 decreases expression ISO quercitrin results in decreased expression of ANAPC15 mRNA CTD PMID:25193878 NCBI chr 1:156,238,640...156,266,005
Ensembl chr 1:156,262,841...156,268,145 		JBrowse link
G Ar androgen receptor increases expression ISO quercitrin results in increased expression of AR mRNA CTD PMID:25193878 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arap2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 increases expression ISO quercitrin results in increased expression of ARAP2 mRNA CTD PMID:25193878 NCBI chr14:46,717,657...46,917,326
Ensembl chr14:46,718,760...46,917,154 		JBrowse link
G Asb6 ankyrin repeat and SOCS box-containing 6 increases expression ISO quercitrin results in increased expression of ASB6 mRNA CTD PMID:25193878 NCBI chr 3:14,110,628...14,115,276
Ensembl chr 3:14,110,628...14,115,242 		JBrowse link
G Atg7 autophagy related 7 decreases expression ISO quercitrin results in decreased expression of ATG7 mRNA CTD PMID:25193878 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 affects expression ISO quercitrin affects the expression of BAIAP2 mRNA CTD PMID:25193878 NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of BAX protein] CTD PMID:23138875 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bdkrb1 bradykinin receptor B1 decreases expression ISO quercitrin results in decreased expression of BDKRB1 mRNA CTD PMID:25193878 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression ISO quercitrin results in decreased expression of CAMK2B mRNA CTD PMID:25193878 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions		 ISO
EXP		 quercitrin results in increased activity of CASP3 protein
quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of CASP3 protein]		 CTD PMID:23138875 PMID:25193878 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 increases expression ISO quercitrin results in increased expression of CASP8 mRNA CTD PMID:25193878 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Ccr9 C-C motif chemokine receptor 9 decreases expression ISO quercitrin results in decreased expression of CCR9 mRNA CTD PMID:25193878 NCBI chr 8:123,396,157...123,410,199
Ensembl chr 8:123,395,813...123,413,969 		JBrowse link
G Ccrl2 C-C motif chemokine receptor like 2 increases expression ISO quercitrin results in increased expression of CCRL2 mRNA CTD PMID:25193878 NCBI chr 8:111,034,279...111,036,914
Ensembl chr 8:111,034,279...111,036,664 		JBrowse link
G Cd302 CD302 molecule decreases expression ISO quercitrin results in decreased expression of CD302 mRNA CTD PMID:25193878 NCBI chr 3:44,722,324...44,756,045
Ensembl chr 3:44,722,325...44,756,045 		JBrowse link
G Cd38 CD38 molecule decreases expression ISO quercitrin results in decreased expression of CD38 mRNA CTD PMID:25193878 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986 		JBrowse link
G Cd74 CD74 molecule affects expression ISO quercitrin affects the expression of CD74 mRNA CTD PMID:25193878 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Cdh1 cadherin 1 decreases expression ISO quercitrin results in decreased expression of CDH1 mRNA CTD PMID:25193878 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO quercitrin results in decreased expression of CDKN3 mRNA CTD PMID:25193878 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945 		JBrowse link
G Celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 increases expression ISO quercitrin results in increased expression of CELSR3 mRNA CTD PMID:25193878 NCBI chr 8:109,530,597...109,558,360
Ensembl chr 8:109,530,641...109,558,354 		JBrowse link
G Cep95 centrosomal protein 95 increases expression ISO quercitrin results in increased expression of CEP95 mRNA CTD PMID:25193878 NCBI chr10:91,732,111...91,760,095
Ensembl chr10:91,732,111...91,760,092 		JBrowse link
G Cers5 ceramide synthase 5 increases expression ISO quercitrin results in increased expression of CERS5 mRNA CTD PMID:25193878 NCBI chr 7:130,859,993...130,897,979
Ensembl chr 7:130,859,990...130,897,947 		JBrowse link
G Cfap298 cilia and flagella associated protein 298 decreases expression ISO quercitrin results in decreased expression of CFAP298 mRNA CTD PMID:25193878 NCBI chr11:30,181,916...30,191,302
Ensembl chr11:30,181,905...30,191,346 		JBrowse link
G Chd2 chromodomain helicase DNA binding protein 2 decreases expression ISO quercitrin results in decreased expression of CHD2 mRNA CTD PMID:25193878 NCBI chr 1:127,188,146...127,317,041
Ensembl chr 1:127,190,059...127,300,502 		JBrowse link
G Cldn10 claudin 10 affects expression ISO quercitrin affects the expression of CLDN10 mRNA CTD PMID:25193878 NCBI chr15:95,862,785...95,954,526
Ensembl chr15:95,862,760...95,954,526 		JBrowse link
G Cldn23 claudin 23 affects expression ISO quercitrin affects the expression of CLDN23 mRNA CTD PMID:25193878 NCBI chr16:56,413,677...56,415,401
Ensembl chr16:56,413,381...56,415,523 		JBrowse link
G Cldn4 claudin 4 affects expression ISO quercitrin affects the expression of CLDN4 mRNA CTD PMID:25193878 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436 		JBrowse link
G Cldn8 claudin 8 affects expression ISO quercitrin affects the expression of CLDN8 mRNA CTD PMID:25193878 NCBI chr11:27,875,857...27,878,106
Ensembl chr11:27,875,692...27,878,513 		JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression ISO quercitrin results in decreased expression of COL3A1 mRNA CTD PMID:25193878 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Coq3 coenzyme Q3 methyltransferase decreases expression ISO quercitrin results in decreased expression of COQ3 mRNA CTD PMID:25193878 NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607 		JBrowse link
G Crisp1 cysteine-rich secretory protein 1 decreases expression ISO quercitrin results in decreased expression of CRISP1 mRNA CTD PMID:25193878 NCBI chr 9:20,741,775...20,768,796
Ensembl chr 9:20,741,777...20,768,796 		JBrowse link
G Cryzl1 crystallin zeta like 1 decreases expression ISO quercitrin results in decreased expression of CRYZL1 mRNA CTD PMID:25193878 NCBI chr11:30,933,140...30,977,936
Ensembl chr11:30,933,144...30,977,867 		JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 affects expression ISO quercitrin affects the expression of CSNK2A1 mRNA CTD PMID:25193878 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696 		JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 affects expression ISO quercitrin affects the expression of CSNK2A2 mRNA CTD PMID:25193878 NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080 		JBrowse link
G Ctdspl2 CTD small phosphatase like 2 decreases expression ISO quercitrin results in decreased expression of CTDSPL2 mRNA CTD PMID:25193878 NCBI chr 3:108,914,650...108,970,620
Ensembl chr 3:108,915,280...108,967,227 		JBrowse link
G Ctsb cathepsin B affects expression ISO quercitrin affects the expression of CTSB mRNA CTD PMID:25193878 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO quercitrin results in decreased activity of CYP1A1 protein CTD PMID:16271822 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO quercitrin results in decreased activity of CYP1B1 protein CTD PMID:16271822 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 increases expression ISO quercitrin results in increased expression of CYP26B1 mRNA CTD PMID:25193878 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628 		JBrowse link
G Dcun1d5 defective in cullin neddylation 1 domain containing 5 decreases expression ISO quercitrin results in decreased expression of DCUN1D5 mRNA CTD PMID:25193878 NCBI chr 8:4,412,266...4,433,380
Ensembl chr 8:4,412,221...4,433,367 		JBrowse link
G Ddx19b DEAD-box helicase 19B decreases expression ISO quercitrin results in decreased expression of DDX19B mRNA CTD PMID:25193878 NCBI chr19:38,968,215...38,998,907
Ensembl chr19:38,968,215...38,997,259 		JBrowse link
G Dele1 DAP3 binding cell death enhancer 1 decreases expression ISO quercitrin results in decreased expression of DELE1 mRNA CTD PMID:25193878 NCBI chr18:30,085,093...30,098,105
Ensembl chr18:30,085,126...30,098,756 		JBrowse link
G Dgkq diacylglycerol kinase, theta affects expression ISO quercitrin affects the expression of DGKQ mRNA CTD PMID:25193878 NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131 		JBrowse link
G Dhrs11 dehydrogenase/reductase 11 decreases activity ISO quercitrin results in decreased activity of DHRS11 protein CTD PMID:30926317 NCBI chr10:69,698,214...69,708,294
Ensembl chr10:69,698,214...69,708,295 		JBrowse link
G Dtwd1 DTW domain containing 1 decreases expression ISO quercitrin results in decreased expression of DTWD1 mRNA CTD PMID:25193878 NCBI chr 3:113,392,402...113,409,322
Ensembl chr 3:113,392,457...113,408,105 		JBrowse link
G Eeig1 estrogen-induced osteoclastogenesis regulator 1 increases expression ISO quercitrin results in increased expression of EEIG1 mRNA CTD PMID:25193878 NCBI chr 3:15,823,147...15,854,651
Ensembl chr 3:15,823,144...15,854,643 		JBrowse link
G Egr2 early growth response 2 increases expression ISO quercitrin results in increased expression of EGR2 mRNA CTD PMID:25193878 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Epas1 endothelial PAS domain protein 1 increases expression ISO quercitrin results in increased expression of EPAS1 mRNA CTD PMID:25193878 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit decreases expression ISO quercitrin results in decreased expression of ERCC1 mRNA CTD PMID:25193878 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression ISO quercitrin results in decreased expression of ERCC2 mRNA CTD PMID:25193878 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102 		JBrowse link
G Eri2 ERI1 exoribonuclease family member 2 increases expression ISO quercitrin results in increased expression of ERI2 mRNA CTD PMID:25193878 NCBI chr 1:174,140,831...174,168,757
Ensembl chr 1:174,141,993...174,168,665 		JBrowse link
G Eva1a eva-1 homolog A, regulator of programmed cell death decreases expression ISO quercitrin results in decreased expression of EVA1A mRNA CTD PMID:25193878 NCBI chr 4:114,593,773...114,643,011
Ensembl chr 4:114,593,341...114,643,011 		JBrowse link
G F11r F11 receptor affects expression ISO quercitrin affects the expression of F11R mRNA CTD PMID:25193878 NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 increases expression ISO quercitrin results in increased expression of F2RL1 mRNA CTD PMID:25193878 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G F2rl2 coagulation factor II (thrombin) receptor-like 2 decreases expression ISO quercitrin results in decreased expression of F2RL2 mRNA CTD PMID:25193878 NCBI chr 2:26,972,054...26,977,098
Ensembl chr 2:26,972,054...26,977,098 		JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO quercitrin results in increased expression of F3 mRNA CTD PMID:25193878 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Faim Fas apoptotic inhibitory molecule increases expression ISO quercitrin results in increased expression of FAIM mRNA CTD PMID:25193878 NCBI chr 8:99,543,877...99,569,499
Ensembl chr 8:99,542,405...99,560,562 		JBrowse link
G Fam216a family with sequence similarity 216, member A decreases expression ISO quercitrin results in decreased expression of FAM216A mRNA CTD PMID:25193878 NCBI chr12:34,198,526...34,207,673
Ensembl chr12:34,198,526...34,207,665 		JBrowse link
G Fam3c FAM3 metabolism regulating signaling molecule C increases expression ISO quercitrin results in increased expression of FAM3C mRNA CTD PMID:25193878 NCBI chr 4:50,839,929...50,887,276
Ensembl chr 4:50,838,818...50,888,078 		JBrowse link
G Fam43a family with sequence similarity 43, member A increases expression ISO quercitrin results in increased expression of FAM43A mRNA CTD PMID:25193878 NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401 		JBrowse link
G Fam50a family with sequence similarity 50, member A increases expression ISO quercitrin results in increased expression of FAM50A mRNA CTD PMID:25193878 NCBI chr  X:152,095,245...152,102,362
Ensembl chr  X:152,095,245...152,102,362 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO quercitrin results in increased expression of FAS mRNA CTD PMID:25193878 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fdcsp follicular dendritic cell secreted protein decreases expression ISO quercitrin results in decreased expression of FDCSP mRNA CTD PMID:25193878 NCBI chr14:20,169,691...20,173,983
Ensembl chr14:20,169,691...20,173,983 		JBrowse link
G Flg filaggrin increases expression ISO quercitrin results in increased expression of FLG mRNA CTD PMID:25193878 NCBI chr 2:178,888,688...178,912,731 JBrowse link
G Fzd4 frizzled class receptor 4 increases expression ISO quercitrin results in increased expression of FZD4 mRNA CTD PMID:25193878 NCBI chr 1:143,280,065...143,288,799
Ensembl chr 1:143,280,065...143,285,724 		JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 increases expression ISO quercitrin results in increased expression of GABBR2 mRNA CTD PMID:25193878 NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha affects expression ISO quercitrin affects the expression of GADD45 mRNA CTD PMID:25193878 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Galk2 galactokinase 2 increases expression ISO quercitrin results in increased expression of GALK2 mRNA CTD PMID:25193878 NCBI chr 3:113,110,057...113,243,014
Ensembl chr 3:113,110,030...113,233,306 		JBrowse link
G Galr3 galanin receptor 3 increases expression ISO quercitrin results in increased expression of GALR3 mRNA CTD PMID:25193878 NCBI chr 7:110,603,525...110,608,429
Ensembl chr 7:110,605,226...110,607,685 		JBrowse link
G Gimap6 GTPase, IMAP family member 6 increases expression ISO quercitrin results in increased expression of GIMAP6 mRNA CTD PMID:25193878 NCBI chr 4:77,653,703...77,659,112
Ensembl chr 4:77,652,610...77,659,116 		JBrowse link
G Glipr1 GLI pathogenesis-related 1 decreases expression ISO quercitrin results in decreased expression of GLIPR1 mRNA CTD PMID:25193878 NCBI chr 7:47,487,342...47,498,974
Ensembl chr 7:47,487,345...47,498,429 		JBrowse link
G Golim4 golgi integral membrane protein 4 increases expression ISO quercitrin results in increased expression of GOLIM4 mRNA CTD PMID:25193878 NCBI chr 2:160,640,932...160,733,475
Ensembl chr 2:160,640,938...160,733,253 		JBrowse link
G Gpr137b G protein-coupled receptor 137B increases expression ISO quercitrin results in increased expression of GPR137B mRNA CTD PMID:25193878 NCBI chr17:86,003,630...86,041,841
Ensembl chr17:85,966,921...86,041,835 		JBrowse link
G Gpr173 G-protein coupled receptor 173 increases expression ISO quercitrin results in increased expression of GPR173 mRNA CTD PMID:25193878 NCBI chr  X:21,446,261...21,471,497
Ensembl chr  X:21,447,361...21,471,498 		JBrowse link
G Gpr174 G protein-coupled receptor 174 increases expression ISO quercitrin results in increased expression of GPR174 mRNA CTD PMID:25193878 NCBI chr  X:72,355,452...72,396,146
Ensembl chr  X:72,355,033...72,397,658 		JBrowse link
G Gpr19 G protein-coupled receptor 19 increases expression ISO quercitrin results in increased expression of GPR19 mRNA CTD PMID:25193878 NCBI chr 4:167,710,944...167,739,232
Ensembl chr 4:167,710,666...167,741,036 		JBrowse link
G Gpr4 G protein-coupled receptor 4 increases expression ISO quercitrin results in increased expression of GPR4 mRNA CTD PMID:25193878 NCBI chr 1:78,865,376...78,877,126
Ensembl chr 1:78,865,409...78,876,599 		JBrowse link
G Gpr63 G protein-coupled receptor 63 increases expression ISO quercitrin results in increased expression of GPR63 mRNA CTD PMID:25193878 NCBI chr 5:38,672,548...38,727,224
Ensembl chr 5:38,635,472...38,727,677 		JBrowse link
G Gpr83 G protein-coupled receptor 83 increases expression ISO quercitrin results in increased expression of GPR83 mRNA CTD PMID:25193878 NCBI chr 8:11,693,540...11,704,028
Ensembl chr 8:11,693,540...11,704,028 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression ISO quercitrin results in decreased expression of GSTP1 mRNA CTD PMID:25193878 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 increases expression ISO quercitrin results in increased expression of HAVCR2 mRNA CTD PMID:25193878 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Hgf hepatocyte growth factor increases expression ISO quercitrin results in increased expression of HGF mRNA CTD PMID:25193878 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hmga2 high mobility group AT-hook 2 increases expression ISO quercitrin results in increased expression of HMGA2 mRNA CTD PMID:25193878 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Hmgb2 high mobility group box 2 decreases expression ISO quercitrin results in decreased expression of HMGB2 mRNA CTD PMID:25193878 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases expression ISO quercitrin results in decreased expression of HNF4A mRNA CTD PMID:25193878 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 affects expression ISO quercitrin affects the expression of HSP90AA1 mRNA CTD PMID:25193878 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like affects expression ISO quercitrin affects the expression of HSPA1L mRNA CTD PMID:25193878 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571 		JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 affects expression ISO quercitrin affects the expression of HSPA6 mRNA CTD PMID:25193878 NCBI chr13:83,271,340...83,275,267 JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 affects expression ISO quercitrin affects the expression of HSPA8 mRNA CTD PMID:25193878 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Ifna1 interferon, alpha 1 affects expression ISO quercitrin affects the expression of IFNA1 mRNA CTD PMID:25193878 NCBI chr 5:103,095,767...103,098,260
Ensembl chr 5:103,097,356...103,097,925 		JBrowse link
G Ifng interferon gamma multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of BAX protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of RELA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased cleavage of PARP1 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of CASP3 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:23138875 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor affects expression ISO quercitrin affects the expression of IGF1R mRNA CTD PMID:25193878 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Il15 interleukin 15 decreases expression ISO quercitrin results in decreased expression of IL15 mRNA CTD PMID:25193878 NCBI chr19:25,640,013...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of BAX protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of RELA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased cleavage of PARP1 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of CASP3 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:23138875 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Ino80c INO80 complex subunit C decreases expression ISO quercitrin results in decreased expression of INO80C mRNA CTD PMID:25193878 NCBI chr18:15,378,764...15,398,574
Ensembl chr18:15,378,770...15,393,403 		JBrowse link
G Inpp4a inositol polyphosphate-4-phosphatase type I A affects expression ISO quercitrin affects the expression of INPP4A mRNA CTD PMID:25193878 NCBI chr 9:39,528,245...39,650,574
Ensembl chr 9:39,528,674...39,646,581 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D affects expression ISO quercitrin affects the expression of INPP5D mRNA CTD PMID:25193878 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746 		JBrowse link
G Insr insulin receptor affects expression ISO quercitrin affects the expression of INSR mRNA CTD PMID:25193878 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 increases expression ISO quercitrin results in increased expression of IRF2BP2 mRNA CTD PMID:25193878 NCBI chr19:54,559,409...54,564,714
Ensembl chr19:54,560,128...54,566,642 		JBrowse link
G Itgb1 integrin subunit beta 1 affects expression ISO quercitrin affects the expression of ITGB1 mRNA CTD PMID:25193878 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Jaml junction adhesion molecule like increases expression ISO quercitrin results in increased expression of JAML mRNA CTD PMID:25193878 NCBI chr 8:45,384,836...45,415,459
Ensembl chr 8:45,383,495...45,416,565 		JBrowse link
G Jpt2 Jupiter microtubule associated homolog 2 increases expression ISO quercitrin results in increased expression of JPT2 mRNA CTD PMID:25193878 NCBI chr10:13,963,135...13,983,212
Ensembl chr10:13,963,137...13,983,170 		JBrowse link
G Kat5 lysine acetyltransferase 5 affects expression ISO quercitrin affects the expression of KAT5 mRNA CTD PMID:25193878 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458 		JBrowse link
G Kdm3a lysine demethylase 3A increases expression ISO quercitrin results in increased expression of KDM3A mRNA CTD PMID:25193878 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073 		JBrowse link
G Kdr kinase insert domain receptor increases expression ISO quercitrin results in increased expression of KDR mRNA CTD PMID:25193878 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression ISO quercitrin results in increased expression of KEAP1 mRNA CTD PMID:25193878 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Klhl28 kelch-like family member 28 increases expression ISO quercitrin results in increased expression of KLHL28 mRNA CTD PMID:25193878 NCBI chr 6:82,987,360...83,018,971
Ensembl chr 6:82,990,945...83,016,164 		JBrowse link
G Krt81 keratin 81 decreases expression ISO quercitrin results in decreased expression of KRT81 mRNA CTD PMID:25193878 NCBI chr 7:132,577,112...132,582,238
Ensembl chr 7:132,576,492...132,582,170 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 affects expression ISO quercitrin affects the expression of LEF1 mRNA CTD PMID:25193878 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794 		JBrowse link
G LOC100911237 zinc finger protein 420-like increases expression ISO quercitrin results in increased expression of ZNF502 mRNA CTD PMID:25193878 NCBI chr 1:28,884,390...28,908,726 JBrowse link
G LOC102552569 P2Y purinoceptor 11-like increases expression ISO quercitrin results in increased expression of P2RY11 mRNA CTD PMID:25193878
G Lpar3 lysophosphatidic acid receptor 3 increases expression ISO quercitrin results in increased expression of LPAR3 mRNA CTD PMID:25193878 NCBI chr 2:235,125,234...235,193,916
Ensembl chr 2:235,149,065...235,193,357 		JBrowse link
G Lpar5 lysophosphatidic acid receptor 5 increases expression ISO quercitrin results in increased expression of LPAR5 mRNA CTD PMID:25193878 NCBI chr 4:157,870,493...157,883,970
Ensembl chr 4:157,881,796...157,882,950 		JBrowse link
G Lpar6 lysophosphatidic acid receptor 6 decreases expression ISO quercitrin results in decreased expression of LPAR6 mRNA CTD PMID:25193878 NCBI chr15:48,416,548...48,418,357
Ensembl chr15:48,416,544...48,422,331 		JBrowse link
G Mat2a methionine adenosyltransferase 2A increases expression ISO quercitrin results in increased expression of MAT2A mRNA CTD PMID:25193878 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493 		JBrowse link
G Mc1r melanocortin 1 receptor increases expression ISO quercitrin results in increased expression of MC1R mRNA CTD PMID:25193878 NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192 		JBrowse link
G Mcts1 MCTS1, re-initiation and release factor decreases expression ISO quercitrin results in decreased expression of MCTS1 mRNA CTD PMID:25193878 NCBI chr  X:117,350,723...117,362,504
Ensembl chr  X:117,350,889...117,362,504 		JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 decreases expression ISO quercitrin results in decreased expression of MRPL12 mRNA CTD PMID:25193878 NCBI chr10:105,758,410...105,762,913
Ensembl chr10:105,758,410...105,762,913 		JBrowse link
G Mrpl22 mitochondrial ribosomal protein L22 decreases expression ISO quercitrin results in decreased expression of MRPL22 mRNA CTD PMID:25193878 NCBI chr10:42,345,446...42,355,779
Ensembl chr10:42,342,776...42,355,779 		JBrowse link
G Msn moesin affects expression ISO quercitrin affects the expression of MSN mRNA CTD PMID:25193878 NCBI chr  X:60,996,043...61,064,011
Ensembl chr  X:60,995,951...61,065,628 		JBrowse link
G Myl2 myosin light chain 2 affects expression ISO quercitrin affects the expression of MYL2 mRNA CTD PMID:25193878 NCBI chr12:34,454,223...34,468,554
Ensembl chr12:34,454,218...34,468,983 		JBrowse link
G Myl9 myosin light chain 9 affects expression ISO quercitrin affects the expression of MYL9 mRNA CTD PMID:25193878 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333 		JBrowse link
G Myom2 myomesin 2 increases expression ISO quercitrin results in increased expression of MYOM2 mRNA CTD PMID:25193878 NCBI chr16:74,520,148...74,592,658
Ensembl chr16:74,520,157...74,592,772 		JBrowse link
G Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit decreases expression ISO quercitrin results in decreased expression of LSMD1 mRNA CTD PMID:25193878 NCBI chr10:54,117,754...54,118,913
Ensembl chr10:54,117,163...54,119,494 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein] CTD PMID:23138875 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nfrkb nuclear factor related to kappa B binding protein increases expression ISO quercitrin results in increased expression of NFRKB mRNA CTD PMID:25193878 NCBI chr 8:29,831,802...29,863,360
Ensembl chr 8:29,831,812...29,863,359