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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:stilbene oxide
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Accession:CHEBI:50006 term browser browse the term
Definition:An epoxide that has formula C14H12O.
Synonyms:exact_synonym: 2,3-diphenyloxirane
 related_synonym: Formula=C14H12O;   InChI=1S/C14H12O/c1-3-7-11(8-4-1)13-14(15-13)12-9-5-2-6-10-12/h1-10,13-14H;   InChIKey=ARCJQKUWGAZPFX-UHFFFAOYSA-N;   SMILES=O1C(C1c1ccccc1)c1ccccc1
 xref: Beilstein:136650;   CAS:17619-97-5
 xref_mesh: MESH:C025906


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stilbene oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP stilbene oxide results in increased expression of ABCC2 mRNA; stilbene oxide results in increased expression of ABCC2 protein CTD PMID:12920174 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression
multiple interactions
EXP stilbene oxide results in increased expression of ABCC3 mRNA; stilbene oxide results in increased expression of ABCC3 protein
[stilbene oxide results in increased expression of ABCC3 protein] which affects the export of Acetaminophen metabolite
CTD PMID:12920174 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression EXP stilbene oxide results in increased expression of ABCC4 mRNA CTD PMID:12920174 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP stilbene oxide results in increased expression of CYP2B1 mRNA CTD PMID:10945841 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP stilbene oxide results in increased expression of CYP2B2 mRNA CTD PMID:10945841 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP stilbene oxide results in increased expression of CYP3A23-3A1 mRNA CTD PMID:10945841 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions
increases metabolic processing
ISO araldite promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide analog]; Dieldrin promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide]; ethylphenylepoxygeranyl ether promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide]; Heptachlor Epoxide promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide]; tridiphane promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide]
EPHX1 protein results in increased metabolism of stilbene oxide; EPHX1 protein results in increased metabolism of stilbene oxide analog
CTD PMID:2043152 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ephx2 epoxide hydrolase 2 increases metabolic processing
multiple interactions
ISO EPHX2 protein results in increased metabolism of stilbene oxide; EPHX2 protein results in increased metabolism of stilbene oxide analog
16 alpha,17-epoxyprogesterone inhibits the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; cholesterol alpha-oxide inhibits the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; Dieldrin promotes the reaction [EPHX2 protein results in increased metabolism of stilbene oxide]; ethylphenylepoxygeranyl ether promotes the reaction [EPHX2 protein results in increased metabolism of stilbene oxide]; Heptachlor Epoxide inhibits the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; Heptachlor Epoxide promotes the reaction [EPHX2 protein results in increased metabolism of stilbene oxide]; Lanosterol analog inhibits the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; limonin inhibits the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; nomilin inhibits the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; tridiphane promotes the reaction [EPHX2 protein results in increased metabolism of stilbene oxide analog]; tridiphane promotes the reaction [EPHX2 protein results in increased metabolism of stilbene oxide]
CTD PMID:2043152 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP stilbene oxide results in increased expression of GSTA3 protein CTD PMID:9794803 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression EXP stilbene oxide results in increased expression of GSTA4 protein CTD PMID:9794803 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP stilbene oxide results in increased expression of GSTA5 protein CTD PMID:9794803 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression EXP stilbene oxide results in increased expression of GSTM3 protein CTD PMID:9794803 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP stilbene oxide results in increased expression of GSTP1 protein CTD PMID:9794803 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases expression EXP stilbene oxide results in increased expression of GSTT1 protein CTD PMID:9794803 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 affects metabolic processing ISO GSTZ1 protein affects the metabolism of stilbene oxide CTD PMID:1846734 NCBI chr 6:111,176,798...111,187,246
Ensembl chr 6:111,176,798...111,187,244
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO stilbene oxide binds to and results in increased activity of NR1I2 protein CTD PMID:20869355 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression ISO stilbene oxide results in increased expression of NR1I3 mRNA CTD PMID:31170421 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19761
    chemical entity 19761
      molecular entity 19759
        main group molecular entity 19653
          gas molecular entity 17750
            oxirane 9523
              epoxide 9522
                stilbene oxide 17
                  cis-stilbene oxide 0
                  trans-stilbene oxide + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19761
    subatomic particle 19759
      composite particle 19759
        hadron 19759
          baryon 19759
            nucleon 19759
              atomic nucleus 19759
                atom 19759
                  main group element atom 19653
                    p-block element atom 19653
                      carbon group element atom 19569
                        carbon atom 19559
                          organic molecular entity 19559
                            organic molecule 19493
                              organic cyclic compound 19318
                                organic heterocyclic compound 18510
                                  organic heteromonocyclic compound 16986
                                    saturated organic heteromonocyclic parent 9543
                                      oxirane 9523
                                        epoxide 9522
                                          stilbene oxide 17
                                            cis-stilbene oxide 0
                                            trans-stilbene oxide + 0
paths to the root