Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fenarimol
go back to main search page
Accession:CHEBI:4998 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-fenarimol. A sterol demethylation inhibitor, it is used as a fungicide for the treatment of blackspot, mildew and rust in tomatoes, peppers and melons, but is not approved for use within the European Union.
Synonyms:exact_synonym: rac-(2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol
 related_synonym: (2-chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol;   (RS)-2,4'-dichloro-alpha-(pyrimidin-5-yl)benzhydryl alcohol;   2,4'-dichloro-alpha(pyrimidin-5-yl)benzhydryl alcohol;   EL 222;   Formula=C17H12Cl2N2O;   Rimidin;   Rubigan;   alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol;   rac-(R)-(2-chlorophenyl)(4-chlorophenyl)(pyrimidin-5-yl)methanol;   rac-fenarimol
 xref: CAS:60168-88-9;   HMDB:HMDB0040599;   KEGG:C11226
 xref_mesh: MESH:C033789
 xref: PMID:12146625;   PMID:14700530;   PMID:15866470;   PMID:18372651;   PMID:22955670;   PMID:23664474;   PMID:8637508;   Patent:US3818009;   Patent:US3869456;   Patent:US3887708;   Pesticides:fenarimol;   Reaxys:5972869;   Wikipedia:Fenarimol



show annotations for term's descendants           Sort by:
 
fenarimol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 decreases expression EXP fenarimol results in decreased expression of ABCA1 mRNA CTD PMID:28970091 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Ar androgen receptor affects binding
multiple interactions
ISO fenarimol binds to AR protein
Dihydrotestosterone inhibits the reaction [fenarimol results in increased activity of AR protein]; fenarimol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; fenarimol inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; fenarimol inhibits the reaction [Metribolone results in increased activity of AR protein]
CTD PMID:15064155 PMID:15253041 PMID:18324785 PMID:26602169 PMID:33049310 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression ISO fenarimol results in increased expression of CYP17A1 mRNA; fenarimol results in increased expression of CYP17A1 protein CTD PMID:21722721 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity
increases expression
ISO fenarimol results in decreased activity of CYP19A1 protein
fenarimol results in increased expression of CYP19A1 mRNA; fenarimol results in increased expression of CYP19A1 protein
CTD PMID:10806373 PMID:11884232 PMID:12127262 PMID:16996190 PMID:21722721 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [fenarimol co-treated with acephate] affects the expression of CYP1A1 protein; [fenarimol co-treated with vinclozolin co-treated with acephate] affects the expression of CYP1A1 protein; [fenarimol co-treated with vinclozolin] affects the expression of CYP1A1 protein CTD PMID:17686559 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [fenarimol co-treated with acephate] affects the expression of CYP1A2 protein; [fenarimol co-treated with vinclozolin co-treated with acephate] affects the expression of CYP1A2 protein; [fenarimol co-treated with vinclozolin] affects the expression of CYP1A2 protein CTD PMID:17686559 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression EXP fenarimol results in increased expression of CYP26A1 mRNA CTD PMID:28970091 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions ISO [fenarimol co-treated with acephate] affects the expression of CYP2B1 protein; [fenarimol co-treated with vinclozolin co-treated with acephate] affects the expression of CYP2B1 protein; [fenarimol co-treated with vinclozolin] affects the expression of CYP2B1 protein CTD PMID:17686559 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 multiple interactions ISO [fenarimol co-treated with acephate] affects the expression of CYP2B2 protein; [fenarimol co-treated with vinclozolin co-treated with acephate] affects the expression of CYP2B2 protein; [fenarimol co-treated with vinclozolin] affects the expression of CYP2B2 protein CTD PMID:17686559 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [fenarimol co-treated with acephate] affects the expression of CYP2E1 protein; [fenarimol co-treated with vinclozolin co-treated with acephate] affects the expression of CYP2E1 protein; [fenarimol co-treated with vinclozolin] affects the expression of CYP2E1 protein CTD PMID:17686559 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression EXP
ISO
fenarimol results in increased expression of CYP51 mRNA CTD PMID:28970091 PMID:29337257 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase increases expression EXP fenarimol results in increased expression of DHCR7 mRNA CTD PMID:28970091 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases expression EXP fenarimol results in increased expression of DHRS3 mRNA CTD PMID:28970091 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression EXP fenarimol results in increased expression of DUSP5 mRNA CTD PMID:28970091 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
JBrowse link
G Esr1 estrogen receptor 1 affects binding
increases activity
multiple interactions
decreases expression
ISO fenarimol binds to ESR1 protein
fenarimol results in increased activity of ESR1 protein
[Chlorpyrifos co-treated with fenarimol co-treated with Estradiol] results in increased activity of ESR1 protein; afimoxifene inhibits the reaction [[fenarimol co-treated with Estradiol] results in increased activity of ESR1 protein]; afimoxifene inhibits the reaction [fenarimol results in increased activity of ESR1 protein]; fenarimol binds to and results in increased activity of ESR1 protein; fenarimol promotes the reaction [Estradiol results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [[fenarimol co-treated with Estradiol] results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [fenarimol results in increased activity of ESR1 protein]
fenarimol results in decreased expression of ESR1 mRNA
CTD PMID:10789375 PMID:15064155 PMID:15253041 PMID:15261991 PMID:16626760 More... NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases activity
increases expression
ISO fenarimol binds to and results in increased activity of ESR2 protein; fenarimol promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]
fenarimol results in increased activity of ESR2 protein
fenarimol results in increased expression of ESR2 mRNA
CTD PMID:15064155 PMID:15261991 PMID:21722721 PMID:26812056 PMID:33049310 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression EXP fenarimol results in increased expression of FDFT1 mRNA CTD PMID:28970091 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fshb follicle stimulating hormone subunit beta increases expression EXP fenarimol results in increased expression of FSHB protein CTD PMID:16324804 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Gbx2 gastrulation brain homeobox 2 increases expression EXP fenarimol results in increased expression of GBX2 mRNA CTD PMID:28970091 NCBI chr 9:90,509,633...90,512,212
Ensembl chr 9:90,509,633...90,512,212
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases activity EXP fenarimol results in increased activity of GGT1 protein CTD PMID:2387028 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression EXP fenarimol results in increased expression of HMGCR mRNA CTD PMID:28970091 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression EXP fenarimol results in increased expression of HMGCS1 mRNA CTD PMID:28970091 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 increases expression ISO fenarimol results in increased expression of HSD3B1 mRNA CTD PMID:21722721 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression EXP fenarimol results in decreased expression of IFRD1 mRNA CTD PMID:28970091 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression EXP fenarimol results in decreased expression of IGF1 mRNA CTD PMID:15590119 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Lhx1 LIM homeobox 1 increases expression EXP fenarimol results in increased expression of LHX1 mRNA CTD PMID:28970091 NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617
JBrowse link
G Lrrc75a leucine rich repeat containing 75A increases expression EXP fenarimol results in increased expression of LRRC75A mRNA CTD PMID:28970091 NCBI chr10:47,298,222...47,343,244 JBrowse link
G Ltf lactotransferrin decreases expression EXP fenarimol results in decreased expression of LTF mRNA CTD PMID:16324804 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
JBrowse link
G Msmo1 methylsterol monooxygenase 1 increases expression EXP fenarimol results in increased expression of MSMO1 mRNA CTD PMID:28970091 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
JBrowse link
G Ngfr nerve growth factor receptor increases expression EXP fenarimol results in increased expression of NGFR mRNA CTD PMID:28970091 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Nobox NOBOX oogenesis homeobox increases expression ISO fenarimol results in increased expression of NOBOX mRNA; fenarimol results in increased expression of NOBOX protein CTD PMID:21722721 NCBI chr 4:72,128,931...72,134,436
Ensembl chr 4:72,128,931...72,134,436
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions
ISO fenarimol results in increased activity of NR1I2 protein
fenarimol binds to and results in increased activity of NR1I2 protein
CTD PMID:16565514 PMID:21115097 PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like increases expression EXP fenarimol results in increased expression of NSDHL mRNA CTD PMID:28970091 NCBI chr  X:150,775,034...150,807,161
Ensembl chr  X:150,775,080...150,807,142
JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression EXP fenarimol results in decreased expression of ODC1 mRNA CTD PMID:15590119 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO fenarimol binds to and results in increased activity of PPARG protein CTD PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Rarb retinoic acid receptor, beta increases expression EXP fenarimol results in increased expression of RARB mRNA CTD PMID:28970091 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rasd1 ras related dexamethasone induced 1 increases expression EXP fenarimol results in increased expression of RASD1 mRNA CTD PMID:28970091 NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186
JBrowse link
G Sc5d sterol-C5-desaturase increases expression EXP fenarimol results in increased expression of SC5D mRNA CTD PMID:28970091 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273
JBrowse link
G Scd stearoyl-CoA desaturase increases expression EXP fenarimol results in increased expression of SCD1 mRNA CTD PMID:28970091 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Scgb2a1 secretoglobin, family 2A, member 1 decreases expression EXP fenarimol results in decreased expression of SCGB2A2 mRNA CTD PMID:15590119 NCBI chr 1:206,497,848...206,501,211
Ensembl chr 1:206,497,849...206,501,211
Ensembl chr 1:206,497,849...206,501,211
JBrowse link
G Scube1 signal peptide, CUB domain and EGF like domain containing 1 increases expression EXP fenarimol results in increased expression of SCUBE1 mRNA CTD PMID:28970091 NCBI chr 7:114,759,016...114,880,995
Ensembl chr 7:114,759,010...114,880,940
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 decreases activity ISO fenarimol results in decreased activity of SRD5A2 protein CTD PMID:17218080 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 increases expression EXP fenarimol results in increased expression of SREBF2 mRNA CTD PMID:28970091 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 increases expression EXP fenarimol results in increased expression of ST3GAL3 mRNA CTD PMID:28970091 NCBI chr 5:131,470,348...131,670,794
Ensembl chr 5:131,470,348...131,670,810
JBrowse link
G Stambpl1 STAM binding protein-like 1 increases expression EXP fenarimol results in increased expression of STAMBPL1 mRNA CTD PMID:28970091 NCBI chr 1:231,699,620...231,745,034
Ensembl chr 1:231,699,995...231,745,032
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO fenarimol binds to and results in decreased activity of THRA protein CTD PMID:33049310 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO fenarimol binds to and results in decreased activity of THRB protein CTD PMID:33049310 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Trdmt1 tRNA aspartic acid methyltransferase 1 decreases expression EXP fenarimol results in decreased expression of TRDMT1 mRNA CTD PMID:28970091 NCBI chr17:76,601,966...76,646,104
Ensembl chr17:76,610,543...76,645,439
JBrowse link
G Zfp496 zinc finger protein 496 increases expression EXP fenarimol results in increased expression of ZFP496 mRNA CTD PMID:28970091 NCBI chr10:44,268,923...44,287,795
Ensembl chr10:44,268,928...44,287,651
JBrowse link
G Zfp703 zinc finger protein 703 increases expression EXP fenarimol results in increased expression of ZFP703 mRNA CTD PMID:28970091 NCBI chr16:65,076,507...65,080,677
Ensembl chr16:65,076,507...65,080,677
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      chemical substance 13190
        mixture 12396
          racemate 10478
            fenarimol 50
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic molecule 19549
                              organic cyclic compound 19343
                                carbocyclic compound 18316
                                  benzenoid aromatic compound 17484
                                    benzenes 17274
                                      chlorobenzenes 13837
                                        monochlorobenzenes 9834
                                          (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol 50
                                            (R)-fenarimol 50
                                              fenarimol 50
paths to the root