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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:zinc dichloride
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Accession:CHEBI:49976 term browser browse the term
Definition:A compound of zinc and chloride ions in the ratio 1:2. It exists in four crystalline forms, in each of which the Zn(2+) ions are trigonal planar coordinated to four chloride ions.
Synonyms:exact_synonym: zinc(2+) chloride;   zinc(II) chloride
 related_synonym: Formula=Cl2Zn;   InChI=1S/2ClH.Zn/h2*1H;/q;;+2/p-2;   InChIKey=JIAARYAFYJHUJI-UHFFFAOYSA-L;   SMILES=[Cl-].[Cl-].[Zn++];   Zinkchlorid;   ZnCl2;   butter of zinc;   chlorure de zinc;   dichlorozinc;   zinc chloride;   zinc chloride, anhydrous
 xref: CAS:7646-85-7;   Gmelin:430396;   KEGG:D02058
 xref_mesh: MESH:C016837
 xref: MolBase:1125;   PMID:23021350;   PMID:23399499;   PMID:23471775;   PMID:23514640;   PMID:23546181;   PMID:23574241;   PMID:23739012;   PMID:23761032;   PMID:23763136;   PMID:29079364;   PMID:7615984;   PMID:9730919;   Wikipedia:Zinc_Chloride



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zinc dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions EXP
ISO
zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ABCB1 mRNA]
zinc chloride inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]
CTD PMID:19714248 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCB6 ATP binding cassette subfamily B member 6 (Langereis blood group) multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ABCB6 mRNA] CTD PMID:22202117 NCBI chr 2:219,209,772...219,218,958
Ensembl chr 2:219,209,772...219,218,994
JBrowse link
G ACHE acetylcholinesterase (Cartwright blood group) multiple interactions ISO [zinc chloride results in increased abundance of Zinc] inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased activity of ACHE protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of ACHE protein] CTD PMID:19429256 PMID:29233033 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G ACO2 aconitase 2 multiple interactions EXP [Citric Acid co-treated with zinc chloride] results in decreased activity of ACO2 protein CTD PMID:16624386 NCBI chr22:41,469,117...41,528,974
Ensembl chr22:41,447,830...41,529,273
JBrowse link
G ACTB actin beta multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of ACTB mRNA CTD PMID:31588059 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
JBrowse link
G ADAM2 ADAM metallopeptidase domain 2 decreases expression EXP zinc chloride results in decreased expression of ADAM2 mRNA CTD PMID:16870260 NCBI chr 8:39,743,735...39,838,227
Ensembl chr 8:39,743,735...39,838,227
JBrowse link
G ADGRE1 adhesion G protein-coupled receptor E1 multiple interactions
increases expression
ISO N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein] CTD PMID:18509044 NCBI chr19:6,887,579...6,940,450
Ensembl chr19:6,887,566...6,940,459
JBrowse link
G ADM adrenomedullin multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ADM mRNA] CTD PMID:22202117 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397
JBrowse link
G ADORA1 adenosine A1 receptor multiple interactions ISO zinc chloride inhibits the reaction [N(6)-cyclohexyladenosine binds to ADORA1 protein] CTD PMID:10413299 NCBI chr 1:203,127,726...203,167,405
Ensembl chr 1:203,090,654...203,167,405
JBrowse link
G AFP alpha fetoprotein decreases expression EXP zinc chloride results in decreased expression of AFP mRNA CTD PMID:18947441 NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174
JBrowse link
G AGO2 argonaute RISC catalytic component 2 multiple interactions EXP [Clioquinol co-treated with zinc chloride] results in decreased expression of AGO2 mRNA; [Clioquinol co-treated with zinc chloride] results in decreased expression of AGO2 protein CTD PMID:22415087 NCBI chr 8:140,520,156...140,642,313
Ensembl chr 8:140,520,156...140,635,633
JBrowse link
G AK4 adenylate kinase 4 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of AK4 mRNA] CTD PMID:22202117 NCBI chr 1:65,147,552...65,232,145
Ensembl chr 1:65,147,549...65,232,145
JBrowse link
G AKT1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions
ISO zinc chloride results in increased phosphorylation of AKT1 protein
wortmannin inhibits the reaction [zinc chloride results in increased phosphorylation of AKT1 protein]
CTD PMID:11340092 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G ALAD aminolevulinate dehydratase multiple interactions ISO
EXP
[zinc chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]] which affects the abundance of Mercury; zinc chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]
zinc chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]; zinc chloride inhibits the reaction [Mercuric Chloride results in increased activity of ALAD protein]
lead nitrate inhibits the reaction [zinc chloride promotes the reaction [Dithiothreitol results in increased activity of ALAD protein]]; triethyllead acetate inhibits the reaction [zinc chloride promotes the reaction [Dithiothreitol results in increased activity of ALAD protein]]; zinc chloride promotes the reaction [Dithiothreitol results in increased activity of ALAD protein]
CTD PMID:2061546 PMID:14615064 PMID:22413763 PMID:24619859 PMID:24679358 NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290
JBrowse link
G ALDOA aldolase, fructose-bisphosphate A multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ALDOA mRNA] CTD PMID:22202117 NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457
JBrowse link
G ALDOC aldolase, fructose-bisphosphate C multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ALDOC mRNA] CTD PMID:22202117 NCBI chr17:28,573,120...28,576,895
Ensembl chr17:28,573,115...28,576,948
JBrowse link
G ALPL alkaline phosphatase, biomineralization associated multiple interactions
increases activity
ISO [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of ALPL mRNA
Cadmium inhibits the reaction [zinc chloride results in increased activity of ALPL protein]; zinc chloride inhibits the reaction [Cadmium results in decreased activity of ALPL protein]
CTD PMID:19913120 PMID:26214600 NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410
JBrowse link
G ANG angiogenin multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANG mRNA] CTD PMID:22202117 NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,684,177...20,698,971
JBrowse link
G ANGPTL4 angiopoietin like 4 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANGPTL4 mRNA] CTD PMID:22202117 NCBI chr19:8,364,155...8,374,370
Ensembl chr19:8,363,289...8,374,370
JBrowse link
G ANKRD37 ankyrin repeat domain 37 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANKRD37 mRNA] CTD PMID:22202117 NCBI chr 4:185,396,841...185,400,723
Ensembl chr 4:185,396,021...185,400,628
JBrowse link
G ANKZF1 ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANKZF1 mRNA] CTD PMID:22202117 NCBI chr 2:219,229,806...219,236,679
Ensembl chr 2:219,229,783...219,236,679
JBrowse link
G AR androgen receptor multiple interactions ISO Androgens inhibits the reaction [zinc chloride inhibits the reaction [Androgens binds to AR protein]]; Dithiothreitol inhibits the reaction [zinc chloride inhibits the reaction [Androgens binds to AR protein]]; zinc chloride inhibits the reaction [Androgens binds to AR protein] CTD PMID:6323860 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619
JBrowse link
G ARG2 arginase 2 increases expression EXP zinc chloride results in increased expression of ARG2 mRNA CTD PMID:18947441 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708
JBrowse link
G ARRB2 arrestin beta 2 affects localization EXP zinc chloride affects the localization of ARRB2 protein CTD PMID:16959833 NCBI chr17:4,710,632...4,721,497
Ensembl chr17:4,710,596...4,721,499
JBrowse link
G ATF2 activating transcription factor 2 multiple interactions ISO [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein] CTD PMID:30768131 NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382
JBrowse link
G ATF4 activating transcription factor 4 decreases expression EXP zinc chloride results in decreased expression of ATF4 mRNA CTD PMID:18947441 NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683
JBrowse link
G ATP6V1B2 ATPase H+ transporting V1 subunit B2 decreases expression EXP zinc chloride results in decreased expression of ATP6V1B2 mRNA CTD PMID:18947441 NCBI chr 8:20,197,381...20,221,696
Ensembl chr 8:20,197,381...20,226,819
JBrowse link
G ATP7B ATPase copper transporting beta decreases expression
increases expression
EXP zinc chloride results in decreased expression of ATP7B mRNA
zinc chloride results in increased expression of ATP7B mRNA
CTD PMID:18947441 NCBI chr13:51,932,669...52,012,132
Ensembl chr13:51,930,436...52,012,125
JBrowse link
G BAG3 BAG cochaperone 3 increases expression
multiple interactions
EXP zinc chloride results in increased expression of BAG3 mRNA
zinc chloride results in increased expression of and affects the localization of BAG3 protein
CTD PMID:12706811 PMID:16870260 NCBI chr10:119,651,380...119,677,819
Ensembl chr10:119,651,380...119,677,819
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP
ISO
[Citric Acid co-treated with zinc chloride] results in increased expression of BAX protein
zinc chloride promotes the reaction [Doxorubicin results in increased expression of BAX mRNA]
zinc chloride affects the reaction [Cadmium Chloride results in increased expression of BAX protein]
CTD PMID:16624386 PMID:19714248 PMID:28390674 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BBC3 BCL2 binding component 3 multiple interactions ISO zinc chloride promotes the reaction [Doxorubicin results in increased expression of BBC3 mRNA] CTD PMID:19714248 NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions EXP
ISO
[Citric Acid co-treated with zinc chloride] results in decreased expression of BCL2 protein; zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of BCL2 mRNA]; zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of BCL2 protein]; zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of BCL2 mRNA]
zinc chloride inhibits the reaction [Doxorubicin results in increased expression of BCL2 mRNA]
CTD PMID:16624386 PMID:17786326 PMID:19714248 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2A1 BCL2 related protein A1 increases expression EXP zinc chloride results in increased expression of BCL2A1 mRNA CTD PMID:21540303 NCBI chr15:79,960,892...79,971,196
Ensembl chr15:79,960,892...79,971,196
JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions EXP [Citric Acid co-treated with zinc chloride] results in decreased expression of BCL2L1 protein CTD PMID:16624386 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions ISO zinc chloride affects the reaction [Cadmium Chloride affects the expression of BDNF mRNA] CTD PMID:29548726 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein multiple interactions ISO [zinc chloride co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of BGLAP mRNA; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of BGLAP mRNA CTD PMID:19913120 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
JBrowse link
G BHLHE40 basic helix-loop-helix family member e40 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of BHLHE40 mRNA] CTD PMID:22202117 NCBI chr 3:4,979,437...4,985,323
Ensembl chr 3:4,979,437...4,985,323
JBrowse link
G BNIP3L BCL2 interacting protein 3 like multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of BNIP3L mRNA] CTD PMID:22202117 NCBI chr 8:26,383,054...26,413,127
Ensembl chr 8:26,383,054...26,505,636
JBrowse link
G BOP1 BOP1 ribosomal biogenesis factor multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of BOP1 mRNA] CTD PMID:22202117 NCBI chr 8:144,262,045...144,291,438
Ensembl chr 8:144,262,045...144,291,438
JBrowse link
G C3 complement C3 increases expression EXP zinc chloride results in increased expression of C3 mRNA CTD PMID:19428942 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G CA13 carbonic anhydrase 13 increases expression ISO zinc chloride results in increased expression of CAR13 mRNA CTD PMID:19000923 NCBI chr 8:85,245,458...85,284,073
Ensembl chr 8:85,220,587...85,284,073
JBrowse link
G CA9 carbonic anhydrase 9 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of CA9 mRNA] CTD PMID:22202117 NCBI chr 9:35,673,928...35,681,159
Ensembl chr 9:35,673,928...35,681,159
JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H decreases activity
multiple interactions
ISO zinc chloride results in decreased activity of CACNA1H protein
zinc chloride inhibits the reaction [Vincristine results in increased expression of CACNA1H protein]
CTD PMID:34286406 NCBI chr16:1,153,106...1,221,768
Ensembl chr16:1,153,106...1,221,771
JBrowse link
G CALD1 caldesmon 1 increases expression EXP zinc chloride results in increased expression of CALD1 mRNA CTD PMID:16870260 NCBI chr 7:134,745,467...134,970,729
Ensembl chr 7:134,744,252...134,970,729
JBrowse link
G CASP12 caspase 12 (gene/pseudogene) multiple interactions EXP [Citric Acid co-treated with zinc chloride] results in increased activity of CASP12 protein CTD PMID:16624386 NCBI chr11:104,885,718...104,898,460
Ensembl chr11:104,885,718...104,898,670
JBrowse link
G CASP3 caspase 3 multiple interactions EXP [Citric Acid co-treated with zinc chloride] results in increased activity of CASP3 protein CTD PMID:16624386 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP9 caspase 9 multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of CASP9 mRNA] CTD PMID:28390674 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase multiple interactions
increases activity
increases expression
ISO
EXP
zinc chloride inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of CAT protein]
zinc chloride results in increased activity of CAT protein
zinc chloride results in increased expression of CAT mRNA
CTD PMID:9330853 PMID:19429256 PMID:23726800 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCDC102B coiled-coil domain containing 102B increases expression EXP zinc chloride results in increased expression of CCDC102B mRNA CTD PMID:16870260 NCBI chr18:68,715,216...69,058,121
Ensembl chr18:68,715,209...69,055,189
JBrowse link
G CCL11 C-C motif chemokine ligand 11 increases expression EXP zinc chloride results in increased expression of CCL11 mRNA CTD PMID:19428942 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334
JBrowse link
G CCL15 C-C motif chemokine ligand 15 decreases expression EXP zinc chloride results in decreased expression of CCL15 mRNA CTD PMID:19428942 NCBI chr17:35,997,582...36,001,553
Ensembl chr17:35,996,440...36,001,553
JBrowse link
G CCL17 C-C motif chemokine ligand 17 decreases expression EXP zinc chloride results in decreased expression of CCL17 mRNA CTD PMID:19428942 NCBI chr16:57,396,093...57,416,063
Ensembl chr16:57,404,767...57,416,063
JBrowse link
G CCL19 C-C motif chemokine ligand 19 decreases expression EXP zinc chloride results in decreased expression of CCL19 mRNA CTD PMID:19428942 NCBI chr 9:34,689,570...34,691,276
Ensembl chr 9:34,689,570...34,691,276
JBrowse link
G CCL20 C-C motif chemokine ligand 20 increases expression EXP zinc chloride results in increased expression of CCL20 mRNA CTD PMID:19428942 PMID:21540303 PMID:27427241 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564
JBrowse link
G CCL24 C-C motif chemokine ligand 24 decreases expression EXP zinc chloride results in decreased expression of CCL24 mRNA CTD PMID:19428942 NCBI chr 7:75,810,825...75,823,372
Ensembl chr 7:75,810,825...75,823,356
JBrowse link
G CCL26 C-C motif chemokine ligand 26 increases expression EXP zinc chloride results in increased expression of CCL26 mRNA CTD PMID:19428942 NCBI chr 7:75,769,524...75,791,597
Ensembl chr 7:75,769,533...75,789,896
JBrowse link
G CCNB1 cyclin B1 increases expression ISO zinc chloride results in increased expression of CCNB1 mRNA CTD PMID:19000923 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
JBrowse link
G CCNG1 cyclin G1 multiple interactions ISO zinc chloride affects the reaction [Cadmium Chloride results in increased expression of CCNG1 mRNA] CTD PMID:16842966 NCBI chr 5:163,437,571...163,457,640
Ensembl chr 5:163,437,569...163,446,151
JBrowse link
G CCNG2 cyclin G2 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of CCNG2 mRNA] CTD PMID:22202117 NCBI chr 4:77,157,207...77,170,060
Ensembl chr 4:77,157,207...77,433,388
JBrowse link
G CCR6 C-C motif chemokine receptor 6 decreases expression EXP zinc chloride results in decreased expression of CCR6 mRNA CTD PMID:19428942 NCBI chr 6:167,111,795...167,139,141
Ensembl chr 6:167,111,807...167,139,141
JBrowse link
G CCR8 C-C motif chemokine receptor 8 decreases expression EXP zinc chloride results in decreased expression of CCR8 mRNA CTD PMID:19428942 NCBI chr 3:39,329,709...39,333,680
Ensembl chr 3:39,329,709...39,333,680
JBrowse link
G CD86 CD86 molecule decreases expression ISO zinc chloride results in decreased expression of CD86 protein CTD PMID:24284788 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G CD9 CD9 molecule increases expression EXP zinc chloride results in increased expression of CD9 mRNA CTD PMID:16870260 NCBI chr12:6,199,946...6,238,266
Ensembl chr12:6,199,715...6,238,271
JBrowse link
G CDH17 cadherin 17 decreases expression EXP zinc chloride results in decreased expression of CDH17 mRNA CTD PMID:18947441 NCBI chr 8:94,127,162...94,217,278
Ensembl chr 8:94,127,162...94,217,303
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions EXP [Citric Acid co-treated with zinc chloride] results in increased expression of CDKN1A protein CTD PMID:16624386 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B decreases expression EXP zinc chloride results in decreased expression of CDKN1B mRNA CTD PMID:21540303 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B decreases expression EXP zinc chloride results in decreased expression of CDKN2B mRNA CTD PMID:21540303 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305
JBrowse link
G CDR1 cerebellar degeneration related protein 1 decreases expression EXP zinc chloride results in decreased expression of CDR1 mRNA CTD PMID:16870260 NCBI chr  X:140,772,083...140,793,212
Ensembl chr  X:140,783,578...140,784,366
JBrowse link
G CEACAM6 CEA cell adhesion molecule 6 increases expression EXP zinc chloride results in increased expression of CEACAM6 mRNA CTD PMID:18947441 NCBI chr19:41,755,530...41,772,211
Ensembl chr19:41,750,977...41,772,211
JBrowse link
G CFTR CF transmembrane conductance regulator increases expression EXP zinc chloride results in increased expression of CFTR mRNA CTD PMID:16870260 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971
JBrowse link
G CHEK1 checkpoint kinase 1 increases expression ISO zinc chloride results in increased expression of CHEK1 mRNA CTD PMID:19000923 NCBI chr11:125,625,136...125,681,124
Ensembl chr11:125,625,163...125,676,255
JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of CITED2 mRNA] CTD PMID:22202117 NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,374,648
JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions ISO [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of COL1A1 mRNA CTD PMID:19913120 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G COMMD1 copper metabolism domain containing 1 multiple interactions ISO [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK2 protein; [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein CTD PMID:25007851 NCBI chr 2:61,888,391...62,136,058
Ensembl chr 2:61,888,724...62,147,247
JBrowse link
G COX17 cytochrome c oxidase copper chaperone COX17 decreases expression EXP zinc chloride results in decreased expression of COX17 mRNA CTD PMID:18947441 NCBI chr 3:119,663,975...119,677,406
Ensembl chr 3:119,654,513...119,677,454
JBrowse link
G CP ceruloplasmin increases expression EXP zinc chloride results in increased expression of CP mRNA CTD PMID:18947441 NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829
JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 increases expression EXP zinc chloride results in increased expression of CPS1 mRNA CTD PMID:16870260 NCBI chr 2:210,477,685...210,679,107
Ensembl chr 2:210,477,682...210,679,107
JBrowse link
G CRP C-reactive protein increases expression EXP zinc chloride results in increased expression of CRP mRNA CTD PMID:19428942 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G CSF2 colony stimulating factor 2 increases expression
multiple interactions
EXP
ISO
zinc chloride results in increased expression of CSF2 mRNA
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]
CTD PMID:18509044 PMID:21540303 PMID:27427241 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
JBrowse link
G CSRP2 cysteine and glycine rich protein 2 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of CSRP2 mRNA] CTD PMID:22202117 NCBI chr12:76,858,709...76,879,019
Ensembl chr12:76,858,709...76,879,023
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 increases expression EXP zinc chloride results in increased expression of CXCL1 mRNA CTD PMID:19428942 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G CXCL11 C-X-C motif chemokine ligand 11 increases expression EXP zinc chloride results in increased expression of CXCL11 mRNA CTD PMID:19428942 NCBI chr 4:76,033,682...76,036,070
Ensembl chr 4:76,033,682...76,041,415
JBrowse link
G CXCL13 C-X-C motif chemokine ligand 13 decreases expression EXP zinc chloride results in decreased expression of CXCL13 mRNA CTD PMID:19428942 NCBI chr 4:77,511,753...77,611,834
Ensembl chr 4:77,511,753...77,611,834
JBrowse link
G CXCL14 C-X-C motif chemokine ligand 14 increases expression EXP zinc chloride results in increased expression of CXCL14 mRNA CTD PMID:19428942 NCBI chr 5:135,570,679...135,578,991
Ensembl chr 5:135,570,679...135,579,279
JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 increases expression EXP zinc chloride results in increased expression of CXCL5 mRNA CTD PMID:19428942 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677
JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 decreases expression EXP zinc chloride results in decreased expression of CXCL6 mRNA CTD PMID:19428942 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression
increases secretion
multiple interactions
EXP zinc chloride results in increased expression of CXCL8 mRNA
zinc chloride results in increased secretion of CXCL8 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased secretion of CXCL8 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [zinc chloride results in increased secretion of CXCL8 protein]; Acetylcysteine inhibits the reaction [zinc chloride results in increased secretion of CXCL8 protein]; DUOX1 protein affects the reaction [zinc chloride results in increased secretion of CXCL8 protein]; pyrazolanthrone inhibits the reaction [zinc chloride results in increased secretion of CXCL8 protein]; RELA protein affects the reaction [zinc chloride results in increased secretion of CXCL8 protein]; Thiourea inhibits the reaction [zinc chloride results in increased secretion of CXCL8 protein]
CTD PMID:19428942 PMID:21540303 PMID:21842098 PMID:23692033 PMID:27427241 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases stability
multiple interactions
ISO zinc chloride results in increased stability of CYP1A1 mRNA; zinc chloride results in increased stability of CYP1A1 protein
zinc chloride inhibits the reaction [1,10-phenanthroline inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]]
CTD PMID:19896525 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G DCP1B decapping mRNA 1B multiple interactions EXP [Clioquinol co-treated with zinc chloride] results in decreased expression of DCP1B mRNA CTD PMID:22415087 NCBI chr12:1,941,591...2,004,457
Ensembl chr12:1,946,053...2,004,535
JBrowse link
G DDX21 DExD-box helicase 21 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of DDX21 mRNA] CTD PMID:22202117 NCBI chr10:68,956,170...68,985,068
Ensembl chr10:68,956,135...68,985,068
JBrowse link
G DENND2B DENN domain containing 2B increases expression EXP zinc chloride results in increased expression of DENND2B mRNA CTD PMID:16870260 NCBI chr11:8,693,352...8,910,951
Ensembl chr11:8,693,351...8,910,951
JBrowse link
G DHRS2 dehydrogenase/reductase 2 increases expression EXP zinc chloride results in increased expression of DHRS2 mRNA CTD PMID:16870260 NCBI chr14:23,630,115...23,645,639
Ensembl chr14:23,630,115...23,645,639
JBrowse link
G DICER1 dicer 1, ribonuclease III multiple interactions EXP [Clioquinol co-treated with zinc chloride] results in decreased expression of DICER1 protein CTD PMID:22415087 NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010
JBrowse link
G DLL4 delta like canonical Notch ligand 4 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in decreased expression of DLL4 mRNA CTD PMID:31588059 NCBI chr15:40,929,340...40,939,073
Ensembl chr15:40,929,340...40,939,073
JBrowse link
G DRD1 dopamine receptor D1 multiple interactions ISO zinc chloride inhibits the reaction [ecopipam binds to DRD1 protein]; zinc chloride inhibits the reaction [SCH 23390 binds to DRD1 protein] CTD PMID:9109525 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
JBrowse link
G DRD2 dopamine receptor D2 multiple interactions ISO zinc chloride inhibits the reaction [3-N-methylspiperone binds to DRD2 protein]; zinc chloride inhibits the reaction [Haloperidol binds to DRD2 protein] CTD PMID:9109525 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G DROSHA drosha ribonuclease III multiple interactions EXP [Clioquinol co-treated with zinc chloride] affects the expression of DROSHA protein CTD PMID:22415087 NCBI chr 5:31,400,494...31,532,093
Ensembl chr 5:31,400,494...31,532,196
JBrowse link
G DUOX1 dual oxidase 1 multiple interactions EXP DUOX1 protein affects the reaction [zinc chloride results in increased secretion of CXCL8 protein] CTD PMID:27427241 NCBI chr15:45,129,994...45,165,574
Ensembl chr15:45,129,933...45,165,576
JBrowse link
G EGFR epidermal growth factor receptor increases phosphorylation EXP zinc chloride results in increased phosphorylation of EGFR protein CTD PMID:21540303 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of EGLN1 mRNA]; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of EGLN1 protein] CTD PMID:16579968 PMID:22202117 NCBI chr 1:231,363,756...231,422,287
Ensembl chr 1:231,363,751...231,422,287
JBrowse link
G EIF4E eukaryotic translation initiation factor 4E multiple interactions EXP [Clioquinol co-treated with zinc chloride] results in increased expression of EIF4E mRNA; [Clioquinol co-treated with zinc chloride] results in increased expression of EIF4E protein CTD PMID:22415087 NCBI chr 4:98,879,276...98,929,133
Ensembl chr 4:98,879,276...98,929,133
JBrowse link
G ELK1 ETS transcription factor ELK1 multiple interactions
increases activity
ISO zinc chloride results in increased phosphorylation of and results in increased activity of ELK1 protein
zinc chloride results in increased activity of ELK1 protein
CTD PMID:16960431 PMID:20412391 NCBI chr  X:47,635,520...47,650,604
Ensembl chr  X:47,635,521...47,650,604
JBrowse link
G ENO2 enolase 2 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ENO2 mRNA] CTD PMID:22202117 NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698
JBrowse link
G EPO erythropoietin multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of EPO protein]; zinc chloride inhibits the reaction [Oxygen deficiency results in increased expression of EPO mRNA] CTD PMID:11090055 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700
JBrowse link
G F2RL2 coagulation factor II thrombin receptor like 2 decreases expression EXP zinc chloride results in decreased expression of F2RL2 mRNA CTD PMID:16870260 NCBI chr 5:76,615,482...76,623,403
Ensembl chr 5:76,615,482...76,623,413
JBrowse link
G FABP1 fatty acid binding protein 1 decreases expression EXP zinc chloride results in decreased expression of FABP1 mRNA CTD PMID:18947441 NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062
JBrowse link
G FAM162A family with sequence similarity 162 member A multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of FAM162A mRNA] CTD PMID:22202117 NCBI chr 3:122,384,182...122,412,334
Ensembl chr 3:122,384,161...122,412,334
JBrowse link
G FASN fatty acid synthase decreases expression EXP zinc chloride results in decreased expression of FASN mRNA CTD PMID:21540303 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of FOS mRNA] CTD PMID:22202117 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit increases expression ISO zinc chloride results in increased expression of FOSL1 mRNA CTD PMID:19000923 NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573
JBrowse link
G FOXA2 forkhead box A2 decreases expression EXP zinc chloride results in decreased expression of FOXA2 mRNA CTD PMID:21540303 NCBI chr20:22,580,998...22,585,490
Ensembl chr20:22,580,998...22,585,455
JBrowse link
G FOXD1 forkhead box D1 increases expression EXP zinc chloride results in increased expression of FOXD1 mRNA CTD PMID:16870260 NCBI chr 5:73,446,266...73,448,777
Ensembl chr 5:73,444,827...73,448,777
JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO zinc chloride inhibits the reaction [Mercuric Chloride results in increased activity of G6PC1 protein] CTD PMID:22413763 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride results in decreased activity of G6PD protein] CTD PMID:18972399 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression EXP zinc chloride results in increased expression of GADD45A mRNA CTD PMID:33645215 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
JBrowse link
G GBE1 1,4-alpha-glucan branching enzyme 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of GBE1 mRNA] CTD PMID:22202117 NCBI chr 3:81,489,703...81,761,645
Ensembl chr 3:81,489,703...81,761,645
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit multiple interactions
increases expression
EXP zinc chloride promotes the reaction [SLC39A2 protein results in increased expression of GCLC mRNA]
zinc chloride results in increased expression of GCLC mRNA
CTD PMID:18385089 PMID:33645215 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit multiple interactions EXP zinc chloride promotes the reaction [SLC39A2 protein results in increased expression of GCLM mRNA] CTD PMID:18385089 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G GJA1 gap junction protein alpha 1 multiple interactions ISO zinc chloride inhibits the reaction [Vincristine results in increased expression of GJA1 protein] CTD PMID:34286406 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GPX2 glutathione peroxidase 2 increases expression EXP zinc chloride results in increased expression of GPX2 mRNA CTD PMID:18947441 NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746
JBrowse link
G GRIK2 glutamate ionotropic receptor kainate type subunit 2 increases expression EXP zinc chloride results in increased expression of GRIK2 mRNA CTD PMID:16870260 NCBI chr 6:101,393,708...102,070,083
Ensembl chr 6:100,962,701...102,081,622
JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A multiple interactions ISO AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of GRIN2A protein]; zinc chloride results in increased expression of and results in increased phosphorylation of GRIN2A protein CTD PMID:12211081 NCBI chr16:9,753,404...10,182,908
Ensembl chr16:9,753,404...10,182,928
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B multiple interactions ISO AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of GRIN2B protein]; zinc chloride results in increased expression of and results in increased phosphorylation of GRIN2B protein CTD PMID:12211081 NCBI chr12:13,537,337...13,982,134
Ensembl chr12:13,437,942...13,982,002
JBrowse link
G GRM5 glutamate metabotropic receptor 5 multiple interactions
increases expression
ISO Copper inhibits the reaction [zinc chloride results in increased expression of GRM5 protein] CTD PMID:25007851 NCBI chr11:88,504,642...89,065,982
Ensembl chr11:88,504,576...89,065,982
JBrowse link
G GSR glutathione-disulfide reductase multiple interactions EXP
ISO
[Carmustine results in decreased activity of GSR protein] which results in increased susceptibility to zinc chloride
zinc chloride inhibits the reaction [Cadmium Chloride results in increased activity of GSR protein]; zinc chloride inhibits the reaction [Copper results in decreased activity of GSR protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of GSR protein]
CTD PMID:12632252 PMID:19429256 PMID:20600438 PMID:23726800 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTP1 glutathione S-transferase pi 1 multiple interactions ISO [Cadmium Chloride co-treated with zinc chloride] results in increased expression of GSTP1 protein CTD PMID:15602745 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G GYS1 glycogen synthase 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of GYS1 mRNA] CTD PMID:22202117 NCBI chr19:48,968,130...48,993,309
Ensembl chr19:48,968,130...48,993,310
JBrowse link
G H2AX H2A.X variant histone increases expression EXP zinc chloride results in increased expression of H2AX mRNA CTD PMID:18947441 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465
JBrowse link
G HCFC1R1 host cell factor C1 regulator 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HCFC1R1 mRNA] CTD PMID:22202117 NCBI chr16:3,022,620...3,024,286
Ensembl chr16:3,022,625...3,024,286
JBrowse link
G HDAC1 histone deacetylase 1 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in decreased expression of HDAC1 mRNA CTD PMID:31588059 NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635
JBrowse link
G HELLS helicase, lymphoid specific increases expression ISO zinc chloride results in increased expression of HELLS mRNA CTD PMID:19000923 NCBI chr10:94,545,788...94,613,905
Ensembl chr10:94,545,329...94,613,905
JBrowse link
G HEPH hephaestin decreases expression EXP zinc chloride results in decreased expression of HEPH mRNA CTD PMID:18947441 NCBI chr  X:66,162,671...66,268,863
Ensembl chr  X:66,162,671...66,268,867
JBrowse link
G HEXB hexosaminidase subunit beta multiple interactions ISO zinc chloride inhibits the reaction [2-phenylphenol results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [bitertanol results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [Butylated Hydroxyanisole results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [Butylated Hydroxytoluene results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [butylparaben results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [EPN oxon results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [Permethrin results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [prothiophos results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [pyridaben results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [salinomycin results in increased secretion of HEXB protein]; zinc chloride inhibits the reaction [terbufos results in increased secretion of HEXB protein] CTD PMID:15272608 NCBI chr 5:74,640,023...74,721,288
Ensembl chr 5:74,640,023...74,722,647
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions
affects splicing
increases expression
EXP
ISO
Cycloheximide inhibits the reaction [zinc chloride results in increased expression of HIF1A protein alternative form]; zinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin promotes the reaction [HIPK2 protein binds to HIF1A promoter]]]; zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased stability of and results in increased expression of HIF1A protein]; zinc chloride inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]; zinc chloride inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
zinc chloride affects the splicing of HIF1A mRNA
zinc chloride results in increased expression of HIF1A mRNA; zinc chloride results in increased expression of HIF1A mRNA alternative form; zinc chloride results in increased expression of HIF1A protein alternative form
[Doxorubicin co-treated with zinc chloride] results in decreased expression of HIF1A mRNA
CTD PMID:11090055 PMID:11739637 PMID:16579968 PMID:19714248 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HILPDA hypoxia inducible lipid droplet associated multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HILPDA mRNA] CTD PMID:22202117 NCBI chr 7:128,455,878...128,458,418
Ensembl chr 7:128,455,849...128,458,418
JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 multiple interactions EXP
ISO
zinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin promotes the reaction [HIPK2 protein binds to HIF1A promoter]]]; zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of HIPK2 protein]; zinc chloride inhibits the reaction [Oxygen deficiency results in decreased expression of HIPK2 protein]
[Doxorubicin co-treated with zinc chloride] results in increased expression of HIPK2 mRNA
CTD PMID:19714248 NCBI chr 7:139,561,570...139,777,998
Ensembl chr 7:139,561,570...139,777,998
JBrowse link
G HK2 hexokinase 2 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HK2 mRNA] CTD PMID:22202117 NCBI chr 2:74,834,127...74,893,359
Ensembl chr 2:74,834,127...74,893,359
JBrowse link
G HMOX1 heme oxygenase 1 increases expression
multiple interactions
EXP
ISO
zinc chloride results in increased expression of HMOX1 mRNA; zinc chloride results in increased expression of HMOX1 protein
zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HMOX1 mRNA]
HMOX1 enhancer affects the reaction [zinc chloride results in increased expression of HMOX1 mRNA]
CTD PMID:7538129 PMID:16870260 PMID:22202117 PMID:27427241 PMID:33645215 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HSP90AA2P heat shock protein 90 alpha family class A member 2, pseudogene increases expression EXP zinc chloride results in increased expression of HSP90AA2P mRNA CTD PMID:21540303 NCBI chr11:27,888,171...27,891,092
Ensembl chr11:27,888,838...27,891,033
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A increases expression EXP
ISO
zinc chloride results in increased expression of HSPA1A mRNA CTD PMID:12085988 PMID:16870260 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B increases expression ISO zinc chloride results in increased expression of HSPA1B mRNA CTD PMID:12085988 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254
JBrowse link
G HSPA6 heat shock protein family A (Hsp70) member 6 increases expression EXP zinc chloride results in increased expression of HSPA6 mRNA CTD PMID:16870260 NCBI chr 1:161,524,540...161,526,894
Ensembl chr 1:161,524,540...161,526,894
JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 increases expression ISO zinc chloride results in increased expression of HSPD1 protein CTD PMID:19429256 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737
JBrowse link
G IFNA2 interferon alpha 2 decreases expression EXP zinc chloride results in decreased expression of IFNA2 mRNA CTD PMID:19428942 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398
JBrowse link
G IFNG interferon gamma multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in decreased expression of IFNG mRNA; zinc chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]] CTD PMID:8975779 PMID:31588059 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta decreases expression EXP zinc chloride results in decreased expression of IKBKB mRNA CTD PMID:21540303 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460
JBrowse link
G IL10 interleukin 10 increases expression ISO zinc chloride results in increased expression of IL10 mRNA CTD PMID:24284788 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL10RB interleukin 10 receptor subunit beta decreases expression EXP zinc chloride results in decreased expression of IL10RB mRNA CTD PMID:19428942 NCBI chr21:33,266,367...33,297,221
Ensembl chr21:33,266,367...33,311,420
JBrowse link
G IL12B interleukin 12B decreases expression ISO zinc chloride results in decreased expression of IL12B mRNA CTD PMID:24284788 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
JBrowse link
G IL18R1 interleukin 18 receptor 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of IL18R1 mRNA] CTD PMID:22202117 NCBI chr 2:102,355,796...102,398,776
Ensembl chr 2:102,311,529...102,398,777
JBrowse link
G IL1A interleukin 1 alpha increases expression
multiple interactions
ISO zinc chloride results in increased expression of IL1A protein
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of IL1A protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]
CTD PMID:18509044 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta multiple interactions
increases expression
ISO
EXP
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]]
zinc chloride inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
zinc chloride results in increased expression of IL1B mRNA
CTD PMID:9138684 PMID:18509044 PMID:19130485 PMID:27427241 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1RL1 interleukin 1 receptor like 1 increases expression ISO zinc chloride results in increased expression of IL1RL1 mRNA CTD PMID:19000923 NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037
JBrowse link
G IL1RN interleukin 1 receptor antagonist increases expression EXP zinc chloride results in increased expression of IL1RN mRNA CTD PMID:19428942 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016
JBrowse link
G IL3 interleukin 3 multiple interactions
increases expression
ISO N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased expression of IL3 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL3 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL3 protein] CTD PMID:18509044 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204
JBrowse link
G IL36RN interleukin 36 receptor antagonist decreases expression EXP zinc chloride results in decreased expression of IL36RN mRNA CTD PMID:19428942 NCBI chr 2:113,058,638...113,064,744
Ensembl chr 2:113,058,638...113,065,382
JBrowse link
G IL37 interleukin 37 decreases expression EXP zinc chloride results in decreased expression of IL37 mRNA CTD PMID:19428942 NCBI chr 2:112,911,165...112,918,882
Ensembl chr 2:112,911,165...112,918,882
JBrowse link
G IL6 interleukin 6 increases secretion
increases expression
multiple interactions
EXP zinc chloride results in increased secretion of IL6 protein
zinc chloride results in increased expression of IL6 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased secretion of IL6 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [zinc chloride results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [zinc chloride results in increased secretion of IL6 protein]; RELA protein affects the reaction [zinc chloride results in increased secretion of IL6 protein]; Thiourea inhibits the reaction [zinc chloride results in increased secretion of IL6 protein]
CTD PMID:21842098 PMID:27427241 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G INSIG2 insulin induced gene 2 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of INSIG2 mRNA] CTD PMID:22202117 NCBI chr 2:118,088,471...118,110,997
Ensembl chr 2:118,088,452...118,110,997
JBrowse link
G INSR insulin receptor increases phosphorylation ISO zinc chloride results in increased phosphorylation of INSR protein CTD PMID:11340092 NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414
JBrowse link
G IREB2 iron responsive element binding protein 2 increases expression EXP zinc chloride results in increased expression of IREB2 mRNA CTD PMID:18947441 NCBI chr15:78,437,431...78,501,453
Ensembl chr15:78,437,431...78,501,453
JBrowse link
G ITGB6 integrin subunit beta 6 increases expression EXP zinc chloride results in increased expression of ITGB6 mRNA CTD PMID:16870260 NCBI chr 2:160,099,671...160,200,272
Ensembl chr 2:160,099,667...160,200,313
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
EXP
ISO
zinc chloride results in increased expression of JUN mRNA
[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein; Acetylcysteine inhibits the reaction [zinc chloride results in increased expression of JUN mRNA]; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein]
CTD PMID:11306679 PMID:19000923 PMID:21540303 PMID:30768131 PMID:33645215 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit increases expression ISO zinc chloride results in increased expression of JUNB mRNA CTD PMID:19000923 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315
JBrowse link
G KAT5 lysine acetyltransferase 5 multiple interactions EXP zinc chloride affects the reaction [4-aminophenylarsenoxide binds to KAT5 protein] CTD PMID:28837777 NCBI chr11:65,712,018...65,719,604
Ensembl chr11:65,711,996...65,719,604
JBrowse link
G KDM3A lysine demethylase 3A multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of KDM3A mRNA] CTD PMID:22202117 NCBI chr 2:86,437,044...86,492,716
Ensembl chr 2:86,440,647...86,492,716
JBrowse link
G KDM4B lysine demethylase 4B multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of KDM4B mRNA] CTD PMID:22202117 NCBI chr19:4,969,113...5,153,598
Ensembl chr19:4,969,113...5,153,598
JBrowse link
G KEAP1 kelch like ECH associated protein 1 affects folding
multiple interactions
ISO zinc chloride affects the folding of KEAP1 protein
zinc chloride promotes the reaction [KEAP1 protein binds to KEAP1 protein]
CTD PMID:30261176 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
JBrowse link
G KIF5A kinesin family member 5A multiple interactions
decreases activity
EXP Adenosine Triphosphate inhibits the reaction [zinc chloride results in decreased activity of KIF5A protein]; Magnesium Chloride affects the reaction [zinc chloride results in decreased activity of KIF5A protein] CTD PMID:28122263 NCBI chr12:57,550,044...57,586,633
Ensembl chr12:57,546,026...57,586,633
JBrowse link
G LEP leptin increases expression EXP zinc chloride results in increased expression of LEP mRNA CTD PMID:21540303 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
JBrowse link
G LIMCH1 LIM and calponin homology domains 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of LIMCH1 mRNA] CTD PMID:22202117 NCBI chr 4:41,359,607...41,700,044
Ensembl chr 4:41,359,607...41,700,044
JBrowse link
G LTA lymphotoxin alpha decreases expression
increases expression
EXP zinc chloride results in decreased expression of LTA mRNA
zinc chloride results in increased expression of LTA mRNA
CTD PMID:19428942 PMID:21540303 NCBI chr 6:31,560,610...31,574,324
Ensembl chr 6:31,572,054...31,574,324
JBrowse link
G LTB4R leukotriene B4 receptor decreases expression EXP zinc chloride results in decreased expression of LTB4R mRNA CTD PMID:19428942 NCBI chr14:24,311,502...24,318,036
Ensembl chr14:24,311,450...24,318,036
JBrowse link
G MAFF MAF bZIP transcription factor F multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of MAFF mRNA] CTD PMID:22202117 NCBI chr22:38,201,994...38,216,511
Ensembl chr22:38,200,767...38,216,507
JBrowse link
G MAFG MAF bZIP transcription factor G increases expression EXP zinc chloride results in increased expression of MAFG mRNA CTD PMID:11162468 NCBI chr17:81,918,270...81,931,244
Ensembl chr17:81,918,270...81,927,735
JBrowse link
G MAML1 mastermind like transcriptional coactivator 1 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of MAML1 mRNA CTD PMID:31588059 NCBI chr 5:179,732,822...179,777,283
Ensembl chr 5:179,732,822...179,777,283
JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 increases activity ISO zinc chloride results in increased activity of MAP2K4 protein CTD PMID:11306679 NCBI chr17:12,020,877...12,143,828
Ensembl chr17:12,020,829...12,143,830
JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 multiple interactions
increases activity
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased activity of MAP3K1 protein]; PIK3CG protein affects the reaction [zinc chloride results in increased activity of MAP3K1 protein] CTD PMID:11306679 NCBI chr 5:56,815,549...56,896,152
Ensembl chr 5:56,815,549...56,896,152
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
increases activity
ISO N,N'-diphenyl-4-phenylenediamine inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK1 protein]; zinc chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein
zinc chloride results in increased activity of MAPK1 protein
CTD PMID:11306679 PMID:11551972 PMID:16960431 PMID:20412391 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
ISO 1,3-dimethylthiourea inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; Go 6976 inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; manumycin inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; N,N'-diphenyl-4-phenylenediamine inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; Vanadates promotes the reaction [zinc chloride results in increased phosphorylation of MAPK3 protein]; zinc chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:16960431 PMID:20412391 PMID:21575692 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased activity of MAPK8 protein]; [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein; Acetylcysteine inhibits the reaction [zinc chloride results in increased activity of MAPK8 protein]; PIK3CG protein affects the reaction [zinc chloride results in increased activity of MAPK8 protein]; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein]; RAC1 protein affects the reaction [zinc chloride results in increased activity of MAPK8 protein]; zinc chloride inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein]; zinc chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:11306679 PMID:20423716 PMID:30768131 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions ISO zinc chloride inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK9 protein] CTD PMID:20423716 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
JBrowse link
G MCM3 minichromosome maintenance complex component 3 increases expression ISO zinc chloride results in increased expression of MCM3 mRNA CTD PMID:19000923 NCBI chr 6:52,264,015...52,284,742
Ensembl chr 6:52,264,014...52,284,881
JBrowse link
G MIF macrophage migration inhibitory factor decreases expression EXP zinc chloride results in decreased expression of MIF mRNA CTD PMID:18947441 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227
JBrowse link
G MIR130A microRNA 130a multiple interactions EXP [Clioquinol co-treated with zinc chloride] results in decreased expression of MIR130A mRNA CTD PMID:22415087 NCBI chr11:57,641,198...57,641,286
Ensembl chr11:57,641,198...57,641,286
JBrowse link
G MIR15A microRNA 15a multiple interactions EXP [Clioquinol co-treated with zinc chloride] results in decreased expression of MIR15A mRNA CTD PMID:22415087 NCBI chr13:50,049,119...50,049,201
Ensembl chr13:50,049,119...50,049,201
JBrowse link
G MIR223 microRNA 223 multiple interactions EXP [Clioquinol co-treated with zinc chloride] results in decreased expression of MIR223 mRNA CTD PMID:22415087 NCBI chr  X:66,018,870...66,018,979
Ensembl chr  X:66,018,870...66,018,979
JBrowse link
G MIR29A microRNA 29a multiple interactions EXP [Clioquinol co-treated with zinc chloride] results in decreased expression of MIR29A mRNA CTD PMID:22415087 NCBI chr 7:130,876,747...130,876,810
Ensembl chr 7:130,876,747...130,876,810
JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions EXP zinc chloride inhibits the reaction [Ellagic Acid results in decreased activity of and results in decreased secretion of MMP2 protein] CTD PMID:21573219 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP7 matrix metallopeptidase 7 decreases expression EXP zinc chloride results in decreased expression of MMP7 mRNA CTD PMID:21540303 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750
JBrowse link
G MT1A metallothionein 1A increases expression
multiple interactions
ISO zinc chloride results in increased expression of MT1A mRNA; zinc chloride results in increased expression of MT1A protein
zinc chloride promotes the reaction [Glucose results in increased expression of MT1A mRNA]
CTD PMID:8928928 PMID:17637929 PMID:23056475 NCBI chr16:56,638,666...56,640,087
Ensembl chr16:56,638,666...56,640,087
JBrowse link
G MT1E metallothionein 1E increases expression EXP zinc chloride results in increased expression of MT1E mRNA CTD PMID:16870260 NCBI chr16:56,625,781...56,627,112
Ensembl chr16:56,625,475...56,627,112
JBrowse link
G MT1F metallothionein 1F increases expression EXP zinc chloride results in increased expression of MT1F mRNA CTD PMID:16870260 NCBI chr16:56,657,959...56,659,303
Ensembl chr16:56,657,731...56,660,698
JBrowse link
G MT1G metallothionein 1G increases expression EXP zinc chloride results in increased expression of MT1G mRNA CTD PMID:16870260 NCBI chr16:56,666,730...56,668,065
Ensembl chr16:56,666,730...56,668,065
JBrowse link
G MT1H metallothionein 1H increases expression EXP zinc chloride results in increased expression of MT1H mRNA CTD PMID:16870260 PMID:18947441 NCBI chr16:56,669,814...56,671,129
Ensembl chr16:56,669,814...56,671,129
JBrowse link
G MT1HL1 metallothionein 1H like 1 increases expression EXP zinc chloride results in increased expression of MT1HL1 mRNA CTD PMID:16870260 NCBI chr 1:237,004,103...237,004,441
Ensembl chr 1:237,004,103...237,004,441
JBrowse link
G MT1L metallothionein 1L, pseudogene increases expression EXP zinc chloride results in increased expression of MT1L mRNA CTD PMID:16870260 NCBI chr16:56,617,461...56,618,818
Ensembl chr16:56,617,423...56,618,832
JBrowse link
G MT1M metallothionein 1M increases expression EXP zinc chloride results in increased expression of MT1M mRNA CTD PMID:16870260 NCBI chr16:56,632,659...56,633,981
Ensembl chr16:56,632,659...56,633,981
JBrowse link
G MT1X metallothionein 1X multiple interactions
increases expression
affects binding
decreases expression
affects response to substance
EXP
ISO
epigallocatechin gallate inhibits the reaction [zinc chloride results in increased expression of MT1X mRNA]; Grape Seed Proanthocyanidins inhibits the reaction [zinc chloride results in increased expression of MT1X mRNA]
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; bisindolylmaleimide I inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; Dicumarol inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; Edetic Acid inhibits the reaction [zinc chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]]; Genistein inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; Ro 31-8220 inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; Sodium Selenite inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; Wortmannin inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; zinc chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]
zinc chloride binds to MT1 protein
zinc chloride results in decreased expression of MT1 protein
MT1 affects the susceptibility to zinc chloride
zinc chloride results in increased expression of MT1 mRNA; zinc chloride results in increased expression of MT1 protein
CTD PMID:3422486 PMID:11551972 PMID:14998373 PMID:15288509 PMID:16870260 More... NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196
JBrowse link
G MT2A metallothionein 2A multiple interactions
increases expression
affects response to substance
affects binding
EXP
ISO
[zinc chloride co-treated with pyrithione zinc] results in increased expression of MT2A mRNA; Dactinomycin inhibits the reaction [zinc chloride results in increased expression of MT2A mRNA]; epigallocatechin gallate inhibits the reaction [zinc chloride results in increased expression of MT2A mRNA]; Grape Seed Proanthocyanidins inhibits the reaction [zinc chloride results in increased expression of MT2A mRNA]; zinc chloride inhibits the reaction [Lipopolysaccharides results in increased expression of MT2A mRNA]
MT2 affects the susceptibility to zinc chloride
zinc chloride binds to MT2 protein
zinc chloride promotes the reaction [Cadmium Chloride results in increased expression of MT2 mRNA]
zinc chloride results in increased expression of MT2 mRNA; zinc chloride results in increased expression of MT2 protein
zinc chloride promotes the reaction [Glucose results in increased expression of MT2A mRNA]
zinc chloride results in increased expression of MT2A mRNA; zinc chloride results in increased expression of MT2A protein
CTD PMID:9138684 PMID:15288509 PMID:16842966 PMID:16870260 PMID:16987576 More... NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
JBrowse link
G MT3 metallothionein 3 increases expression EXP zinc chloride results in increased expression of MT3 mRNA CTD PMID:18947441 NCBI chr16:56,589,528...56,591,085
Ensembl chr16:56,589,074...56,591,088
JBrowse link
G MTA2 metastasis associated 1 family member 2 decreases expression EXP zinc chloride results in decreased expression of MTA2 mRNA CTD PMID:16870260 NCBI chr11:62,593,214...62,601,865
Ensembl chr11:62,593,214...62,601,865
JBrowse link
G MTF1 metal regulatory transcription factor 1 multiple interactions
decreases expression
affects localization
ISO
EXP
zinc chloride results in increased phosphorylation of and results in increased activity of MTF1 protein
zinc chloride results in decreased expression of MTF1 mRNA
zinc chloride affects the localization of MTF1 protein
CTD PMID:11551972 PMID:16423564 PMID:18947441 NCBI chr 1:37,809,574...37,859,592
Ensembl chr 1:37,809,574...37,859,592
JBrowse link
G MTF2 metal response element binding transcription factor 2 decreases expression EXP zinc chloride results in decreased expression of MTF2 mRNA CTD PMID:18947441 NCBI chr 1:93,079,283...93,139,076
Ensembl chr 1:93,079,235...93,139,079
JBrowse link
G NCF1 neutrophil cytosolic factor 1 multiple interactions
increases response to substance
ISO NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL3 protein]
NCF1 results in increased susceptibility to zinc chloride
CTD PMID:18509044 NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315
JBrowse link
G NDRG1 N-myc downstream regulated 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of NDRG1 mRNA] CTD PMID:22202117 NCBI chr 8:133,237,175...133,297,252
Ensembl chr 8:133,237,175...133,302,022
JBrowse link
G NDUFAF5 NADH:ubiquinone oxidoreductase complex assembly factor 5 decreases expression EXP zinc chloride results in decreased expression of NDUFAF5 mRNA CTD PMID:16870260 NCBI chr20:13,785,028...13,821,580
Ensembl chr20:13,785,007...13,821,580
JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor decreases expression EXP zinc chloride results in decreased expression of NF2 mRNA CTD PMID:16870260 NCBI chr22:29,603,556...29,698,600
Ensembl chr22:29,603,556...29,698,598
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 affects response to substance
multiple interactions
ISO
EXP
[NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to zinc chloride
zinc chloride promotes the reaction [SLC39A2 protein results in increased activity of NFE2L2 protein]
CTD PMID:18385089 PMID:19303893 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 increases activity EXP zinc chloride results in increased activity of NFKB1 protein CTD PMID:21842098 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
JBrowse link
G NIP7 nucleolar pre-rRNA processing protein NIP7 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of NIP7 mRNA] CTD PMID:22202117 NCBI chr16:69,339,772...69,343,106
Ensembl chr16:69,337,996...69,343,106
JBrowse link
G NMNAT1 nicotinamide nucleotide adenylyltransferase 1 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of NMNAT1 mRNA CTD PMID:31588059 NCBI chr 1:9,942,923...9,996,892
Ensembl chr 1:9,943,428...9,985,501
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO zinc chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]] CTD PMID:8975779 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOX4 NADPH oxidase 4 increases expression EXP zinc chloride results in increased expression of NOX4 mRNA CTD PMID:16870260 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187
JBrowse link
G NTN3 netrin 3 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of NTN3 mRNA CTD PMID:31588059 NCBI chr16:2,471,297...2,474,145
Ensembl chr16:2,471,297...2,474,145
JBrowse link
G OR2AG2 olfactory receptor family 2 subfamily AG member 2 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of OR2AG2 mRNA CTD PMID:31588059 NCBI chr11:6,765,626...6,771,976
Ensembl chr11:6,765,626...6,771,976
JBrowse link
G OR4C12 olfactory receptor family 4 subfamily C member 12 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in decreased expression of OR4C12 mRNA CTD PMID:31588059 NCBI chr11:49,981,473...49,982,535
Ensembl chr11:49,981,473...49,982,535
JBrowse link
G ORM1 orosomucoid 1 increases expression ISO zinc chloride results in increased expression of ORM1 mRNA CTD PMID:19000923 NCBI chr 9:114,323,098...114,326,479
Ensembl chr 9:114,323,098...114,326,479
JBrowse link
G ORM2 orosomucoid 2 increases expression ISO zinc chloride results in increased expression of ORM2 mRNA CTD PMID:19000923 NCBI chr 9:114,329,869...114,333,251
Ensembl chr 9:114,329,869...114,333,251
JBrowse link
G P2RX2 purinergic receptor P2X 2 multiple interactions ISO zinc chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein] CTD PMID:16190872 NCBI chr12:132,618,776...132,622,388
Ensembl chr12:132,618,776...132,622,388
JBrowse link
G P4HA1 prolyl 4-hydroxylase subunit alpha 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of P4HA1 mRNA] CTD PMID:22202117 NCBI chr10:73,007,217...73,096,866
Ensembl chr10:73,007,217...73,096,974
JBrowse link
G P4HA2 prolyl 4-hydroxylase subunit alpha 2 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of P4HA2 mRNA] CTD PMID:22202117 NCBI chr 5:132,190,147...132,227,853
Ensembl chr 5:132,190,147...132,295,315
JBrowse link
G PAIP1 poly(A) binding protein interacting protein 1 decreases expression EXP zinc chloride results in decreased expression of PAIP1 mRNA CTD PMID:18947441 NCBI chr 5:43,526,267...43,557,411
Ensembl chr 5:43,526,267...43,557,758
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions
increases response to substance
increases activity
increases expression
EXP
ISO
zinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]]; zinc chloride inhibits the reaction [sodium arsenite results in decreased activity of PARP1 protein]; zinc chloride promotes the reaction [Hydrogen Peroxide results in increased activity of PARP1 protein]
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; acetovanillone inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]; Cibacron Blue F 3GA inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; coomassie Brilliant Blue inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]; NCF1 gene mutant form inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1B protein]; PARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL3 protein]; periodate-oxidized adenosine 5'-triphosphate inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]
PARP1 results in increased susceptibility to zinc chloride
CTD PMID:18509044 PMID:19056730 PMID:19714248 PMID:22253048 PMID:33645215 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PCBD1 pterin-4 alpha-carbinolamine dehydratase 1 increases expression EXP zinc chloride results in increased expression of PCBD1 mRNA CTD PMID:18947441 NCBI chr10:70,882,280...70,888,565
Ensembl chr10:70,882,280...70,888,565
JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions ISO [Cadmium Chloride co-treated with zinc chloride] results in increased expression of PCNA protein CTD PMID:15602745 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G PDAP1 PDGFA associated protein 1 multiple interactions ISO zinc chloride promotes the reaction [Cadmium Chloride results in increased expression of PDAP1 mRNA] CTD PMID:16842966 NCBI chr 7:99,394,673...99,408,597
Ensembl chr 7:99,392,048...99,408,597
JBrowse link
G PDK1 pyruvate dehydrogenase kinase 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PDK1 mRNA] CTD PMID:22202117 NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669
JBrowse link
G PEG3 paternally expressed 3 decreases expression EXP zinc chloride results in decreased expression of PEG3 mRNA CTD PMID:16870260 NCBI chr19:56,810,082...56,840,726
Ensembl chr19:56,810,077...56,840,728
JBrowse link
G PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PFKFB3 mRNA] CTD PMID:22202117 NCBI chr10:6,144,921...6,326,637
Ensembl chr10:6,144,934...6,254,644
JBrowse link
G PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PFKFB4 mRNA] CTD PMID:22202117 NCBI chr 3:48,517,684...48,563,136
Ensembl chr 3:48,517,684...48,562,015
JBrowse link
G PGF placental growth factor increases expression EXP zinc chloride results in increased expression of PGF mRNA CTD PMID:16870260 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626
JBrowse link
G PGK1 phosphoglycerate kinase 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PGK1 mRNA] CTD PMID:22202117 NCBI chr  X:78,104,248...78,129,295
Ensembl chr  X:77,910,739...78,129,295
JBrowse link
G PGM1 phosphoglucomutase 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PGM1 mRNA] CTD PMID:22202117 NCBI chr 1:63,593,411...63,660,245
Ensembl chr 1:63,593,411...63,660,245
JBrowse link
G PHEX phosphate regulating endopeptidase X-linked increases expression ISO zinc chloride results in increased expression of PHEX mRNA CTD PMID:19000923 NCBI chr  X:22,032,325...22,251,310
Ensembl chr  X:22,032,325...22,494,713
JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma multiple interactions ISO PIK3CG protein affects the reaction [zinc chloride results in increased activity of MAP3K1 protein]; PIK3CG protein affects the reaction [zinc chloride results in increased activity of MAPK8 protein] CTD PMID:11306679 NCBI chr 7:106,865,282...106,908,980
Ensembl chr 7:106,865,278...106,908,980
JBrowse link
G PIK3R4 phosphoinositide-3-kinase regulatory subunit 4 increases expression EXP zinc chloride results in increased expression of PIK3R4 mRNA CTD PMID:16870260 NCBI chr 3:130,678,934...130,746,829
Ensembl chr 3:130,678,934...130,746,829
JBrowse link
G PIK3R5 phosphoinositide-3-kinase regulatory subunit 5 increases expression ISO zinc chloride results in increased expression of PIK3R5 mRNA CTD PMID:19000923 NCBI chr17:8,878,916...8,965,707
Ensembl chr17:8,878,911...8,965,712
JBrowse link
G PMP22 peripheral myelin protein 22 increases expression EXP zinc chloride results in increased expression of PMP22 mRNA CTD PMID:18947441 NCBI chr17:15,229,779...15,265,326
Ensembl chr17:15,229,773...15,272,292
JBrowse link
G PRKCA protein kinase C alpha multiple interactions
affects localization
ISO 1,3-dimethylthiourea inhibits the reaction [zinc chloride affects the localization of and results in increased activity of PRKCA protein]; 1,3-dimethylthiourea inhibits the reaction [zinc chloride affects the localization of PRKCA protein]; Glucose promotes the reaction [zinc chloride affects the localization of and results in increased activity of PRKCA protein]; Vanadates promotes the reaction [zinc chloride affects the localization of PRKCA protein]; zinc chloride affects the localization of and results in increased activity of PRKCA protein CTD PMID:20800666 PMID:21575692 NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743
JBrowse link
G PTH1R parathyroid hormone 1 receptor multiple interactions ISO [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of PTH1R mRNA CTD PMID:19913120 NCBI chr 3:46,877,721...46,903,799
Ensembl chr 3:46,877,721...46,903,799
JBrowse link
G RAB20 RAB20, member RAS oncogene family multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of RAB20 mRNA] CTD PMID:22202117 NCBI chr13:110,523,066...110,561,722
Ensembl chr13:110,523,066...110,561,722
JBrowse link
G RAC1 Rac family small GTPase 1 multiple interactions ISO RAC1 protein affects the reaction [zinc chloride results in increased activity of MAPK8 protein] CTD PMID:11306679 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967
JBrowse link
G RAD21 RAD21 cohesin complex component increases expression ISO zinc chloride results in increased expression of RAD21 mRNA CTD PMID:19000923 NCBI chr 8:116,845,934...116,874,776
Ensembl chr 8:116,845,934...116,874,776
JBrowse link
G RAD51AP1 RAD51 associated protein 1 increases expression ISO zinc chloride results in increased expression of RAD51AP1 mRNA CTD PMID:19000923 NCBI chr12:4,538,890...4,560,047
Ensembl chr12:4,538,798...4,560,047
JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions
increases phosphorylation
ISO 1,3-dimethylthiourea inhibits the reaction [zinc chloride results in increased phosphorylation of RAF1 protein]; AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of RAF1 protein]; Go 6976 inhibits the reaction [zinc chloride results in increased phosphorylation of RAF1 protein]; manumycin inhibits the reaction [zinc chloride results in increased phosphorylation of RAF1 protein] CTD PMID:21575692 NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201
JBrowse link
G RANGAP1 Ran GTPase activating protein 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RANGAP1 mRNA] CTD PMID:22202117 NCBI chr22:41,244,779...41,302,369
Ensembl chr22:41,244,779...41,286,187
JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of RBPJ mRNA] CTD PMID:22202117 NCBI chr 4:26,105,449...26,435,131
Ensembl chr 4:26,163,455...26,435,131
JBrowse link
G RECK reversion inducing cysteine rich protein with kazal motifs multiple interactions EXP zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK mRNA]; zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK protein] CTD PMID:21573219 NCBI chr 9:36,036,913...36,124,455
Ensembl chr 9:36,036,913...36,124,455
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions
increases phosphorylation
EXP RELA protein affects the reaction [zinc chloride results in increased secretion of CXCL8 protein]; RELA protein affects the reaction [zinc chloride results in increased secretion of IL6 protein]
zinc chloride results in increased phosphorylation of RELA protein
CTD PMID:27427241 NCBI chr11:65,653,601...65,662,916
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G RIF1 replication timing regulatory factor 1 increases expression ISO zinc chloride results in increased expression of RIF1 mRNA CTD PMID:19000923 NCBI chr 2:151,409,902...151,534,435
Ensembl chr 2:151,409,883...151,508,013
JBrowse link
G RIOK3 RIO kinase 3 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of RIOK3 mRNA] CTD PMID:22202117 NCBI chr18:23,453,287...23,483,140
Ensembl chr18:23,453,287...23,486,603
JBrowse link
G RORA RAR related orphan receptor A multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of RORA mRNA] CTD PMID:22202117 NCBI chr15:60,488,284...61,229,302
Ensembl chr15:60,488,284...61,229,302
JBrowse link
G RPL11 ribosomal protein L11 decreases expression EXP zinc chloride results in decreased expression of RPL11 mRNA CTD PMID:18947441 NCBI chr 1:23,691,779...23,696,835
Ensembl chr 1:23,691,742...23,696,835
JBrowse link
G RRP15 ribosomal RNA processing 15 homolog multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RRP15 mRNA] CTD PMID:22202117 NCBI chr 1:218,285,293...218,337,983
Ensembl chr 1:218,285,293...218,337,983
JBrowse link
G RRS1 ribosome biogenesis regulator 1 homolog multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RRS1 mRNA] CTD PMID:22202117 NCBI chr 8:66,429,014...66,430,733
Ensembl chr 8:66,429,014...66,430,733
JBrowse link
G RUNX2 RUNX family transcription factor 2 multiple interactions ISO [zinc chloride co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of RUNX2 protein; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of RUNX2 mRNA; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of RUNX2 protein CTD PMID:19913120 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349
JBrowse link
G RUVBL1 RuvB like AAA ATPase 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of RUVBL1 mRNA] CTD PMID:22202117 NCBI chr 3:128,064,785...128,153,914
Ensembl chr 3:128,064,778...128,153,914
JBrowse link
G SALL1 spalt like transcription factor 1 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of SALL1 mRNA CTD PMID:31588059 NCBI chr16:51,135,982...51,152,334
Ensembl chr16:51,135,982...51,152,334
JBrowse link
G SAP30 Sin3A associated protein 30 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SAP30 mRNA] CTD PMID:22202117 NCBI chr 4:173,370,954...173,377,532
Ensembl chr 4:173,369,969...173,377,532
JBrowse link
G SBNO1 strawberry notch homolog 1 increases expression EXP zinc chloride results in increased expression of SBNO1 mRNA CTD PMID:16870260 NCBI chr12:123,289,109...123,364,847
Ensembl chr12:123,289,109...123,364,847
JBrowse link
G SCARA3 scavenger receptor class A member 3 decreases expression EXP zinc chloride results in decreased expression of SCARA3 mRNA CTD PMID:16870260 NCBI chr 8:27,633,463...27,734,141
Ensembl chr 8:27,633,868...27,676,776
JBrowse link
G SCARB1 scavenger receptor class B member 1 increases expression ISO zinc chloride results in increased expression of SCARB1 mRNA CTD PMID:19000923 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668
JBrowse link
G SCD stearoyl-CoA desaturase multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SCD mRNA] CTD PMID:22202117 NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826
JBrowse link
G SELPLG selectin P ligand increases expression EXP zinc chloride results in increased expression of SELPLG mRNA CTD PMID:21540303 NCBI chr12:108,621,895...108,633,894
Ensembl chr12:108,621,895...108,633,894
JBrowse link
G SERTAD2 SERTA domain containing 2 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SERTAD2 mRNA] CTD PMID:22202117 NCBI chr 2:64,631,621...64,653,913
Ensembl chr 2:64,631,621...64,751,005
JBrowse link
G SHANK2 SH3 and multiple ankyrin repeat domains 2 multiple interactions
increases expression
ISO [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK2 protein; Copper inhibits the reaction [zinc chloride results in increased expression of SHANK2 protein] CTD PMID:25007851 NCBI chr11:70,467,854...71,253,228
Ensembl chr11:70,467,854...71,252,577
JBrowse link
G SHANK3 SH3 and multiple ankyrin repeat domains 3 multiple interactions
increases expression
ISO [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein; Copper inhibits the reaction [zinc chloride results in increased expression of SHANK3 protein] CTD PMID:25007851 NCBI chr22:50,672,823...50,733,212
Ensembl chr22:50,674,415...50,733,212
JBrowse link
G SLC11A2 solute carrier family 11 member 2 increases transport EXP SLC11A2 protein results in increased transport of zinc chloride CTD PMID:22736759 NCBI chr12:50,952,263...51,028,886
Ensembl chr12:50,979,401...51,028,566
JBrowse link
G SLC16A3 solute carrier family 16 member 3 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SLC16A3 mRNA] CTD PMID:22202117 NCBI chr17:82,217,934...82,240,086
Ensembl chr17:82,217,934...82,261,129
JBrowse link
G SLC1A2 solute carrier family 1 member 2 multiple interactions ISO [Kainic Acid co-treated with zinc chloride] results in decreased expression of SLC1A2 protein CTD PMID:19061913 NCBI chr11:35,251,205...35,420,507
Ensembl chr11:35,251,205...35,420,063
JBrowse link
G SLC1A5 solute carrier family 1 member 5 decreases expression EXP zinc chloride results in decreased expression of SLC1A5 mRNA CTD PMID:18947441 NCBI chr19:46,774,883...46,788,594
Ensembl chr19:46,774,883...46,788,594
JBrowse link
G SLC25A15 solute carrier family 25 member 15 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of SLC25A15 mRNA] CTD PMID:22202117 NCBI chr13:40,789,611...40,812,460
Ensembl chr13:40,789,412...40,812,460
JBrowse link
G SLC2A1 solute carrier family 2 member 1 multiple interactions
increases expression
EXP
ISO
zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SLC2A1 mRNA]
zinc chloride results in increased expression of SLC2A1 mRNA
CTD PMID:19000923 PMID:22202117 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893
JBrowse link
G SLC30A1 solute carrier family 30 member 1 multiple interactions
increases expression
EXP
ISO
epigallocatechin gallate inhibits the reaction [zinc chloride results in increased expression of SLC30A1 mRNA]; zinc chloride inhibits the reaction [Grape Seed Proanthocyanidins results in decreased expression of SLC30A1 mRNA]
zinc chloride affects the reaction [Cadmium Chloride affects the expression of SLC30A1 mRNA]; zinc chloride promotes the reaction [Glucose results in increased expression of SLC30A1 mRNA]
CTD PMID:18947441 PMID:20392624 PMID:20471814 PMID:23056475 PMID:25653005 More... NCBI chr 1:211,571,568...211,579,161
Ensembl chr 1:211,571,568...211,579,161
JBrowse link
G SLC30A2 solute carrier family 30 member 2 increases expression
multiple interactions
ISO zinc chloride results in increased expression of SLC30A2 mRNA
zinc chloride affects the reaction [Cadmium Chloride affects the expression of SLC30A2 mRNA]
CTD PMID:20392624 PMID:25653005 NCBI chr 1:26,037,252...26,046,118
Ensembl chr 1:26,037,252...26,046,118
JBrowse link
G SLC30A4 solute carrier family 30 member 4 multiple interactions ISO zinc chloride affects the reaction [Cadmium Chloride affects the expression of SLC30A4 mRNA] CTD PMID:25653005 NCBI chr15:45,479,606...45,522,755
Ensembl chr15:45,479,606...45,522,755
JBrowse link
G SLC30A5 solute carrier family 30 member 5 decreases expression
multiple interactions
EXP zinc chloride results in decreased expression of SLC30A5 mRNA
Dactinomycin inhibits the reaction [zinc chloride results in decreased expression of SLC30A5 mRNA]
CTD PMID:17234632 PMID:20392624 NCBI chr 5:69,094,014...69,131,069
Ensembl chr 5:69,093,991...69,131,069
JBrowse link
G SLC30A7 solute carrier family 30 member 7 increases expression
decreases expression
EXP zinc chloride results in increased expression of SLC30A7 mRNA
zinc chloride results in decreased expression of SLC30A7 mRNA
CTD PMID:20392624 NCBI chr 1:100,896,090...100,996,078
Ensembl chr 1:100,896,076...100,981,757
JBrowse link
G SLC31A2 solute carrier family 31 member 2 increases expression
decreases expression
EXP zinc chloride results in increased expression of SLC31A2 mRNA
zinc chloride results in decreased expression of SLC31A2 mRNA
CTD PMID:18947441 NCBI chr 9:113,151,007...113,164,140
Ensembl chr 9:113,150,976...113,164,140
JBrowse link
G SLC39A1 solute carrier family 39 member 1 multiple interactions EXP zinc chloride inhibits the reaction [Grape Seed Proanthocyanidins results in increased expression of SLC39A1 mRNA] CTD PMID:20471814 NCBI chr 1:153,959,110...153,968,184
Ensembl chr 1:153,959,099...153,968,184
JBrowse link
G SLC39A2 solute carrier family 39 member 2 multiple interactions
increases expression
EXP [SLC39A2 protein co-treated with zinc chloride] results in increased abundance of Glutathione; zinc chloride promotes the reaction [SLC39A2 protein results in increased activity of NFE2L2 protein]; zinc chloride promotes the reaction [SLC39A2 protein results in increased expression of GCLC mRNA]; zinc chloride promotes the reaction [SLC39A2 protein results in increased expression of GCLM mRNA]
zinc chloride results in increased expression of SLC39A2 mRNA
CTD PMID:18385089 NCBI chr14:20,999,293...21,001,871
Ensembl chr14:20,999,255...21,001,871
JBrowse link
G SLC39A3 solute carrier family 39 member 3 multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of SLC39A3 mRNA] CTD PMID:25653005 NCBI chr19:2,732,524...2,740,076
Ensembl chr19:2,732,204...2,740,028
JBrowse link
G SLC39A4 solute carrier family 39 member 4 multiple interactions
decreases expression
EXP
ISO
zinc chloride inhibits the reaction [Grape Seed Proanthocyanidins results in increased expression of SLC39A4 mRNA]
zinc chloride results in decreased expression of SLC39A4 mRNA
zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of SLC39A4 mRNA]
CTD PMID:20471814 PMID:25653005 NCBI chr 8:144,412,414...144,416,844
Ensembl chr 8:144,409,742...144,416,844
JBrowse link
G SLC39A8 solute carrier family 39 member 8 multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of SLC39A8 mRNA] CTD PMID:25653005 NCBI chr 4:102,251,041...102,345,482
Ensembl chr 4:102,251,080...102,431,258
JBrowse link
G SLC48A1 solute carrier family 48 member 1 increases expression EXP zinc chloride results in increased expression of SLC48A1 mRNA CTD PMID:16870260 NCBI chr12:47,753,934...47,782,751
Ensembl chr12:47,753,916...47,782,751
JBrowse link
G SLC5A1 solute carrier family 5 member 1 multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride inhibits the reaction [SP1 protein binds to and affects the expression of SLC5A1 promoter]]; zinc chloride inhibits the reaction [Cadmium Chloride results in decreased expression of SLC5A1 mRNA] CTD PMID:20060848 NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029
JBrowse link
G SLC5A2 solute carrier family 5 member 2 multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride inhibits the reaction [SP110 protein binds to and affects the expression of SLC5A2 promoter]]; zinc chloride inhibits the reaction [Cadmium Chloride results in decreased expression of SLC5A2 mRNA] CTD PMID:20060848 NCBI chr16:31,483,123...31,490,769
Ensembl chr16:31,483,002...31,490,860
JBrowse link
G SLC9A1 solute carrier family 9 member A1 increases expression EXP zinc chloride results in increased expression of SLC9A1 mRNA CTD PMID:18947441 NCBI chr 1:27,098,809...27,155,125
Ensembl chr 1:27,098,809...27,166,981
JBrowse link
G SORD sorbitol dehydrogenase multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride results in decreased activity of SORD protein] CTD PMID:18972399 NCBI chr15:45,023,195...45,077,185
Ensembl chr15:45,023,147...45,077,185
JBrowse link
G SP1 Sp1 transcription factor multiple interactions
increases activity
ISO
EXP
zinc chloride inhibits the reaction [Cadmium Chloride inhibits the reaction [SP1 protein binds to and affects the expression of SLC5A1 promoter]]
zinc chloride results in increased activity of SP1 protein
CTD PMID:9330853 PMID:20060848 NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446
JBrowse link
G SP110 SP110 nuclear body protein multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride inhibits the reaction [SP110 protein binds to and affects the expression of SLC5A2 promoter]] CTD PMID:20060848 NCBI chr 2:230,165,186...230,225,636
Ensembl chr 2:230,165,186...230,225,729
JBrowse link
G SPAG4 sperm associated antigen 4 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SPAG4 mRNA] CTD PMID:22202117 NCBI chr20:35,615,829...35,621,094
Ensembl chr20:35,615,829...35,621,094
JBrowse link
G SPICE1 spindle and centriole associated protein 1 decreases expression EXP zinc chloride results in decreased expression of SPICE1 mRNA CTD PMID:16870260 NCBI chr 3:113,442,718...113,515,156
Ensembl chr 3:113,442,718...113,515,187
JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 decreases expression EXP zinc chloride results in decreased expression of SPINK1 mRNA CTD PMID:18947441 NCBI chr 5:147,824,582...147,839,196
Ensembl chr 5:147,824,572...147,831,671
JBrowse link
G SPOCK1 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of SPOCK1 mRNA] CTD PMID:22202117 NCBI chr 5:136,975,298...137,499,326
Ensembl chr 5:136,975,298...137,598,379
JBrowse link
G SPP1 secreted phosphoprotein 1 decreases expression
multiple interactions
EXP
ISO
zinc chloride results in decreased expression of SPP1 mRNA
[zinc chloride co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of SPP1 mRNA; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of SPP1 mRNA; zinc chloride promotes the reaction [Calcitriol results in increased activity of SPP1 promoter]
CTD PMID:10777672 PMID:19428942 PMID:19913120 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions
increases phosphorylation
ISO 1,3-dimethylthiourea inhibits the reaction [zinc chloride results in increased phosphorylation of SRC protein]; AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of SRC protein]; Vanadates promotes the reaction [zinc chloride results in increased phosphorylation of SRC protein] CTD PMID:12211081 PMID:21575692 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link
G SRM spermidine synthase multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of SRM mRNA] CTD PMID:22202117 NCBI chr 1:11,054,589...11,060,018
Ensembl chr 1:11,054,584...11,060,020
JBrowse link
G STBD1 starch binding domain 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of STBD1 mRNA] CTD PMID:22202117 NCBI chr 4:76,306,733...76,311,130
Ensembl chr 4:76,306,733...76,311,130
JBrowse link
G STMN1 stathmin 1 increases expression ISO zinc chloride results in increased expression of STMN1 mRNA CTD PMID:19000923 NCBI chr 1:25,884,179...25,906,880
Ensembl chr 1:25,884,181...25,906,991
JBrowse link
G TERT telomerase reverse transcriptase multiple interactions EXP [Citric Acid co-treated with zinc chloride] results in decreased activity of TERT protein CTD PMID:16624386 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068
JBrowse link
G TF transferrin multiple interactions
increases expression
EXP zinc chloride inhibits the reaction [TF protein results in increased uptake of Iron]
zinc chloride results in increased expression of TF mRNA
CTD PMID:11335103 PMID:18947441 NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641
JBrowse link
G TFPI2 tissue factor pathway inhibitor 2 increases expression EXP zinc chloride results in increased expression of TFPI2 mRNA CTD PMID:16870260 NCBI chr 7:93,885,396...93,890,753
Ensembl chr 7:93,885,396...93,890,753
JBrowse link
G TFRC transferrin receptor increases expression ISO zinc chloride results in increased expression of TFRC mRNA CTD PMID:19000923 NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153
JBrowse link
G TMEM45A transmembrane protein 45A multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of TMEM45A mRNA] CTD PMID:22202117 NCBI chr 3:100,492,619...100,577,444
Ensembl chr 3:100,492,619...100,577,444
JBrowse link
G TNF tumor necrosis factor increases expression EXP
ISO
zinc chloride results in increased expression of TNF mRNA CTD PMID:19428942 PMID:21540303 PMID:24284788 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride results in decreased expression of TNFRSF11B protein] CTD PMID:23726800 NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885
JBrowse link
G TNFSF11 TNF superfamily member 11 multiple interactions ISO zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of TNFSF11 protein] CTD PMID:23726800 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013
JBrowse link
G TNFSF14 TNF superfamily member 14 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of TNFSF14 mRNA CTD PMID:31588059 NCBI chr19:6,661,253...6,670,588
Ensembl chr19:6,661,253...6,670,588
JBrowse link
G TP53 tumor protein p53 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein]] CTD PMID:19714248 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TRA2A transformer 2 alpha homolog decreases expression EXP zinc chloride results in decreased expression of TRA2A mRNA CTD PMID:16870260 NCBI chr 7:23,504,780...23,531,981
Ensembl chr 7:23,504,780...23,532,041
JBrowse link
G TSC22D3 TSC22 domain family member 3 multiple interactions ISO [zinc chloride results in increased abundance of Zinc] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:107,713,221...107,777,086
Ensembl chr  X:107,713,221...107,777,342
JBrowse link
G TTR transthyretin multiple interactions ISO [zinc chloride results in increased abundance of Zinc] which results in increased expression of TTR mRNA CTD PMID:31588059 NCBI chr18:31,591,877...31,598,821
Ensembl chr18:31,557,009...31,598,833
JBrowse link
G TUBA1B tubulin alpha 1b increases expression EXP zinc chloride results in increased expression of TUBA1B mRNA CTD PMID:18947441 NCBI chr12:49,127,782...49,131,395
Ensembl chr12:49,127,782...49,131,397
JBrowse link
G UBA1 ubiquitin like modifier activating enzyme 1 multiple interactions EXP zinc chloride promotes the reaction [Dimethyldithiocarbamate results in decreased activity of and results in decreased ubiquitination of UBA1 protein]; zinc chloride results in decreased activity of and results in decreased ubiquitination of UBA1 protein CTD PMID:25714994 NCBI chr  X:47,190,847...47,215,128
Ensembl chr  X:47,190,861...47,215,128
JBrowse link
G UBE2E2 ubiquitin conjugating enzyme E2 E2 increases expression EXP zinc chloride results in increased expression of UBE2E2 mRNA CTD PMID:18947441 NCBI chr 3:23,203,098...23,591,925
Ensembl chr 3:23,203,020...23,591,794
JBrowse link
G UNC5B unc-5 netrin receptor B increases expression EXP zinc chloride results in increased expression of UNC5B mRNA CTD PMID:18947441 NCBI chr10:71,212,570...71,302,864
Ensembl chr10:71,212,570...71,302,864
JBrowse link
G USE1 unconventional SNARE in the ER 1 increases expression EXP zinc chloride results in increased expression of USE1 mRNA CTD PMID:16870260 NCBI chr19:17,215,357...17,219,829
Ensembl chr19:17,215,346...17,219,829
JBrowse link
G UTRN utrophin affects binding EXP zinc chloride binds to UTRN protein CTD PMID:17009962 NCBI chr 6:144,285,335...144,853,034
Ensembl chr 6:144,285,335...144,853,034
JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions EXP
ISO
zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA]
zinc chloride inhibits the reaction [Doxorubicin results in increased expression of VEGFA mRNA]
CTD PMID:19714248 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G WDR4 WD repeat domain 4 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in decreased expression of WDR4 mRNA] CTD PMID:22202117 NCBI chr21:42,843,094...42,892,998
Ensembl chr21:42,843,094...42,879,568
JBrowse link
G WSB1 WD repeat and SOCS box containing 1 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of WSB1 mRNA] CTD PMID:22202117 NCBI chr17:27,294,114...27,315,926
Ensembl chr17:27,294,076...27,315,926
JBrowse link
G XCR1 X-C motif chemokine receptor 1 decreases expression EXP zinc chloride results in decreased expression of XCR1 mRNA CTD PMID:19428942 NCBI chr 3:46,017,007...46,085,844
Ensembl chr 3:46,016,990...46,085,825
JBrowse link
G YEATS2 YEATS domain containing 2 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of YEATS2 mRNA] CTD PMID:22202117 NCBI chr 3:183,697,797...183,812,624
Ensembl chr 3:183,697,797...183,812,624
JBrowse link
G ZNF292 zinc finger protein 292 multiple interactions EXP zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ZNF292 mRNA] CTD PMID:22202117 NCBI chr 6:87,155,565...87,265,943
Ensembl chr 6:87,151,803...87,265,943
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 25538
    role 25475
      chemical role 23666
        acceptor 19208
          Lewis acid 6182
            zinc dichloride 326
              fast blue salt B 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 25538
    subatomic particle 25509
      composite particle 25509
        hadron 25509
          baryon 25509
            nucleon 25509
              atomic nucleus 25509
                atom 25509
                  main group element atom 25358
                    p-block element atom 25358
                      halogen 20175
                        chlorine atom 19349
                          chlorine molecular entity 19349
                            elemental chlorine 8430
                              monoatomic chlorine 8414
                                chloride 8414
                                  chloride salt 8414
                                    inorganic chloride 8146
                                      zinc dichloride 326
                                        fast blue salt B 0
paths to the root