CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | nickel(2+) |
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Accession: | CHEBI:49786
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browse the term
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Definition: | A nickel cation in which the nickel carries a double positive charge. |
Synonyms: | exact_synonym: | nickel(2+) ion; nickel(II) cation |
| related_synonym: | Formula=Ni; InChI=1S/Ni/q+2; InChIKey=VEQPNABPJHWNSG-UHFFFAOYSA-N; NICKEL (II) ION; Ni(2+); Ni2+; Nickel, ion (Ni2+); SMILES=[Ni++]; nickelous ion |
| alt_id: | CHEBI:25517; CHEBI:49785 |
| xref: | CAS:14701-22-5; Gmelin:6859; PDBeChem:NI; PMID:20456924 |
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Aass |
aminoadipate-semialdehyde synthase |
decreases expression |
ISO |
nickel sulfate results in decreased expression of AASS mRNA |
CTD |
PMID:22714537 |
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NCBI chr 4:50,152,005...50,208,935
Ensembl chr 4:50,152,452...50,200,328
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Abca5 |
ATP binding cassette subfamily A member 5 |
increases expression |
ISO |
nickel sulfate results in increased expression of ABCA5 mRNA |
CTD |
PMID:22714537 |
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NCBI chr10:98,573,226...98,645,028
Ensembl chr10:98,576,039...98,644,938
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Abca6 |
ATP binding cassette subfamily A member 6 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ABCA6 mRNA |
CTD |
PMID:16780908 PMID:17374397 |
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NCBI chr10:98,477,716...98,546,699
Ensembl chr10:98,478,067...98,544,447
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Abcc1 |
ATP binding cassette subfamily C member 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of ABCC1 mRNA |
CTD |
PMID:16780908 |
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NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
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Abcc3 |
ATP binding cassette subfamily C member 3 |
increases expression |
ISO |
nickel sulfate results in increased expression of ABCC3 mRNA |
CTD |
PMID:16314067 PMID:22714537 |
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NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
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Abhd10 |
abhydrolase domain containing 10, depalmitoylase |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ABHD10 mRNA |
CTD |
PMID:17374397 |
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NCBI chr11:60,053,719...60,068,142
Ensembl chr11:60,054,408...60,066,739 Ensembl chr11:60,054,408...60,066,739
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Abhd12 |
abhydrolase domain containing 12, lysophospholipase |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ABHD12 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 3:146,630,298...146,690,375
Ensembl chr 3:146,630,299...146,690,375
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Abhd17a |
abhydrolase domain containing 17A, depalmitoylase |
increases expression |
ISO |
nickel sulfate results in increased expression of ABHD17A mRNA |
CTD |
PMID:22714537 |
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NCBI chr 7:11,992,543...12,000,978
Ensembl chr 7:11,992,543...11,998,973
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Abi3bp |
ABI family member 3 binding protein |
increases expression |
ISO |
nickel sulfate results in increased expression of ABI3BP mRNA |
CTD |
PMID:22714537 |
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NCBI chr11:46,206,932...46,422,791
Ensembl chr11:46,208,075...46,369,577
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Ablim1 |
actin-binding LIM protein 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ABLIM1 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 1:277,853,877...278,043,096
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Abraxas1 |
abraxas 1, BRCA1 A complex subunit |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ABRAXAS1 mRNA |
CTD |
PMID:22714537 |
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NCBI chr14:10,424,674...10,439,010
Ensembl chr14:10,424,674...10,439,003
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Acbd7 |
acyl-CoA binding domain containing 7 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ACBD7 mRNA |
CTD |
PMID:22714537 |
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NCBI chr17:78,904,549...78,913,372
Ensembl chr17:78,904,873...78,910,671
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Aco1 |
aconitase 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ACO1 mRNA |
CTD |
PMID:16780908 |
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NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
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Aco2 |
aconitase 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of ACO2 mRNA |
CTD |
PMID:18651567 |
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NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
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Acot13 |
acyl-CoA thioesterase 13 |
increases expression |
ISO |
nickel sulfate results in increased expression of ACOT13 mRNA |
CTD |
PMID:22714537 |
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NCBI chr17:42,241,141...42,253,611
Ensembl chr17:42,241,159...42,253,649
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Acot2 |
acyl-CoA thioesterase 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of ACOT2 mRNA |
CTD |
PMID:16780908 |
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NCBI chr 6:107,460,596...107,468,324
Ensembl chr 6:107,460,668...107,467,487
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Acot4 |
acyl-CoA thioesterase 4 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ACOT4 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 6:107,517,668...107,522,952
Ensembl chr 6:107,517,668...107,522,952
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Acox2 |
acyl-CoA oxidase 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of ACOX2 mRNA |
CTD |
PMID:16314067 |
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NCBI chr15:18,449,304...18,481,472
Ensembl chr15:18,451,144...18,481,470
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Acsl5 |
acyl-CoA synthetase long-chain family member 5 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ACSL5 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
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Acss2 |
acyl-CoA synthetase short-chain family member 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of ACSS2 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 3:151,032,925...151,075,856
Ensembl chr 3:151,032,952...151,075,856
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Acta1 |
actin, alpha 1, skeletal muscle |
increases expression |
ISO |
nickel sulfate results in increased expression of ACTA1 mRNA |
CTD |
PMID:16166746 |
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NCBI chr19:56,674,072...56,677,084
Ensembl chr19:56,674,074...56,677,084
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Actc1 |
actin, alpha, cardiac muscle 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ACTC1 mRNA |
CTD |
PMID:16100012 |
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NCBI chr 3:105,507,403...105,512,939
Ensembl chr 3:105,507,403...105,512,939
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Actg2 |
actin gamma 2, smooth muscle |
increases expression |
ISO |
nickel sulfate results in increased expression of ACTG2 mRNA |
CTD |
PMID:16780908 |
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NCBI chr 4:115,215,160...115,239,746
Ensembl chr 4:115,215,060...115,239,723
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Acvr1 |
activin A receptor type 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of ACVR1 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
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Acvr1b |
activin A receptor type 1B |
increases expression |
ISO |
nickel sulfate results in increased expression of ACVR1B mRNA |
CTD |
PMID:18651567 |
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NCBI chr 7:142,817,174...142,858,365
Ensembl chr 7:142,817,157...142,860,572
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Ada |
adenosine deaminase |
increases expression |
ISO |
nickel sulfate results in increased expression of ADA mRNA |
CTD |
PMID:22714537 |
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NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
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Adam12 |
ADAM metallopeptidase domain 12 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ADAM12 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 1:205,951,840...206,286,294
Ensembl chr 1:205,956,342...206,282,575
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Adam19 |
ADAM metallopeptidase domain 19 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ADAM19 mRNA |
CTD |
PMID:16166746 |
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NCBI chr10:31,146,107...31,240,582
Ensembl chr10:31,146,107...31,240,582
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Adam32 |
ADAM metallopeptidase domain 32 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ADAM32 mRNA |
CTD |
PMID:22714537 |
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NCBI chr16:71,889,035...71,999,151
Ensembl chr16:71,889,235...71,999,148
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Adam8 |
ADAM metallopeptidase domain 8 |
increases expression |
ISO |
nickel sulfate results in increased expression of ADAM8 mRNA |
CTD |
PMID:16166746 |
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NCBI chr 1:212,317,510...212,332,895
Ensembl chr 1:212,317,848...212,330,349
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Adamts12 |
ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ADAMTS12 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 2:61,039,072...61,340,687
Ensembl chr 2:61,039,053...61,340,697
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Adamts3 |
ADAM metallopeptidase with thrombospondin type 1, motif 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ADAMTS3 mRNA |
CTD |
PMID:22714537 |
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NCBI chr14:19,866,278...20,072,896
Ensembl chr14:19,866,408...20,070,994
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Adamtsl1 |
ADAMTS-like 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ADAMTSL1 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 5:103,789,443...104,753,866
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Adamtsl3 |
ADAMTS-like 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ADAMTSL3 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 1:144,238,958...144,561,065
Ensembl chr 1:144,239,020...144,561,247
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Adck2 |
aarF domain containing kinase 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of ADCK2 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 4:67,359,531...67,373,390
Ensembl chr 4:67,359,531...67,372,416
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Adcy7 |
adenylate cyclase 7 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ADCY7 mRNA |
CTD |
PMID:16780908 |
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NCBI chr19:19,702,307...19,762,973
Ensembl chr19:19,704,859...19,727,081
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Add3 |
adducin 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ADD3 mRNA |
CTD |
PMID:18651567 |
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NCBI chr 1:273,854,195...273,961,982
Ensembl chr 1:273,854,248...273,961,982
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Adgrg1 |
adhesion G protein-coupled receptor G1 |
increases expression |
ISO |
nickel sulfate results in increased expression of ADGRG1 mRNA |
CTD |
PMID:22714537 |
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NCBI chr19:10,423,534...10,460,674
Ensembl chr19:10,423,501...10,460,674
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Adm |
adrenomedullin |
increases expression decreases expression |
ISO |
nickel sulfate results in increased expression of ADM mRNA nickel sulfate results in decreased expression of ADM mRNA |
CTD |
PMID:18651567 PMID:22714537 |
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NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
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Adora2a |
adenosine A2a receptor |
increases expression |
ISO |
nickel sulfate results in increased expression of ADORA2A mRNA |
CTD |
PMID:16780908 PMID:22714537 |
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NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
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Adora2b |
adenosine A2B receptor |
increases expression |
ISO |
nickel sulfate results in increased expression of ADORA2B mRNA |
CTD |
PMID:16314067 |
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NCBI chr10:48,569,563...48,586,366
Ensembl chr10:48,569,555...48,586,365
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Afap1l2 |
actin filament associated protein 1-like 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of AFAP1L2 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 1:277,730,760...277,827,299
Ensembl chr 1:277,730,760...277,827,269
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Aff3 |
AF4/FMR2 family, member 3 |
increases expression |
ISO |
nickel sulfate results in increased expression of AFF3 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 9:44,837,979...45,291,964
Ensembl chr 9:44,839,960...45,292,047
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Agbl5 |
AGBL carboxypeptidase 5 |
increases expression |
ISO |
nickel sulfate results in increased expression of AGBL5 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 6:26,837,299...26,857,234
Ensembl chr 6:26,838,036...26,855,658
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Agmat |
agmatinase |
decreases expression |
ISO |
nickel sulfate results in decreased expression of AGMAT mRNA |
CTD |
PMID:22714537 |
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NCBI chr 5:160,306,754...160,321,951
Ensembl chr 5:160,306,727...160,321,066
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Agtpbp1 |
ATP/GTP binding carboxypeptidase 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of AGTPBP1 mRNA |
CTD |
PMID:22714537 |
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NCBI chr17:5,510,009...5,614,416
Ensembl chr17:5,511,385...5,614,435
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Ahcyl1 |
adenosylhomocysteinase-like 1 |
affects expression |
ISO |
nickel sulfate affects the expression of AHCYL1 mRNA |
CTD |
PMID:18202158 |
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NCBI chr 2:210,438,884...210,474,350
Ensembl chr 2:210,438,893...210,473,761
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Ahdc1 |
AT hook, DNA binding motif, containing 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of AHDC1 mRNA |
CTD |
PMID:18651567 |
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NCBI chr 5:151,209,894...151,277,192
Ensembl chr 5:151,211,342...151,277,165
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Ahnak2 |
AHNAK nucleoprotein 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of AHNAK2 mRNA |
CTD |
PMID:18651567 |
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NCBI chr 6:137,335,273...137,380,219
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Akap11 |
A-kinase anchoring protein 11 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of AKAP11 mRNA |
CTD |
PMID:22714537 |
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NCBI chr15:60,722,138...60,766,673
Ensembl chr15:60,722,160...60,766,579
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Akr1b1 |
aldo-keto reductase family 1 member B |
increases expression |
ISO |
nickel sulfate results in increased expression of AKR1B1 mRNA |
CTD |
PMID:20566472 |
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NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
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Akr1b10 |
aldo-keto reductase family 1 member B10 |
increases expression |
ISO |
nickel sulfate results in increased expression of AKR1B10 mRNA |
CTD |
PMID:20566472 |
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NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
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Akr1c3 |
aldo-keto reductase family 1, member C3 |
increases expression |
ISO |
nickel sulfate results in increased expression of AKR1C3 mRNA |
CTD |
PMID:20566472 |
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NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
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Akr1e2 |
aldo-keto reductase family 1, member E2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of AKR1E2 mRNA |
CTD |
PMID:22714537 |
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NCBI chr17:69,365,437...69,379,944
Ensembl chr17:69,365,453...69,379,947
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Akt1 |
AKT serine/threonine kinase 1 |
increases phosphorylation |
ISO |
nickel sulfate results in increased phosphorylation of AKT1 protein |
CTD |
PMID:23445166 |
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NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
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Alcam |
activated leukocyte cell adhesion molecule |
increases expression |
ISO |
nickel sulfate results in increased expression of ALCAM mRNA |
CTD |
PMID:16780908 |
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NCBI chr11:50,780,735...50,985,083
Ensembl chr11:50,781,127...50,985,083
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Aldh1l2 |
aldehyde dehydrogenase 1 family, member L2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ALDH1L2 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 7:26,375,866...26,425,838
Ensembl chr 7:26,375,866...26,425,108
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Aldh3a2 |
aldehyde dehydrogenase 3 family, member A2 |
increases expression |
ISO |
nickel sulfate results in increased expression of ALDH3A2 mRNA |
CTD |
PMID:22714537 |
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NCBI chr10:47,525,486...47,546,535
Ensembl chr10:47,525,493...47,546,345
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Aldh5a1 |
aldehyde dehydrogenase 5 family, member A1 |
increases expression |
ISO |
nickel sulfate results in increased expression of ALDH5A1 mRNA |
CTD |
PMID:22714537 |
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NCBI chr17:42,133,076...42,159,413
Ensembl chr17:42,133,076...42,159,413
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Aldoc |
aldolase, fructose-bisphosphate C |
increases expression |
ISO |
nickel sulfate results in increased expression of ALDOC mRNA |
CTD |
PMID:17382205 PMID:22714537 |
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NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
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Alg5 |
ALG5, dolichyl-phosphate beta-glucosyltransferase |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ALG5 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 2:143,932,242...143,946,472
Ensembl chr 2:143,932,739...143,946,466
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Alox5ap |
arachidonate 5-lipoxygenase activating protein |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ALOX5AP mRNA |
CTD |
PMID:16780908 |
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NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154
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Alpk2 |
alpha-kinase 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ALPK2 mRNA |
CTD |
PMID:22714537 |
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NCBI chr18:60,960,009...61,072,116
Ensembl chr18:60,960,662...61,057,365
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Alyref |
Aly/REF export factor |
increases expression |
ISO |
nickel sulfate results in increased expression of THOC4 mRNA |
CTD |
PMID:22714537 |
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NCBI chr10:109,768,593...109,774,639
Ensembl chr10:109,770,876...109,774,639
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Ampd3 |
adenosine monophosphate deaminase 3 |
affects expression |
ISO |
nickel sulfate affects the expression of AMPD3 mRNA |
CTD |
PMID:18202158 |
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NCBI chr 1:175,585,301...175,630,479
Ensembl chr 1:175,586,097...175,630,467
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Angptl4 |
angiopoietin-like 4 |
multiple interactions increases expression |
ISO |
[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of ANGPTL4 mRNA nickel sulfate results in increased expression of ANGPTL4 mRNA |
CTD |
PMID:16166746 PMID:17382205 PMID:18832182 |
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NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
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Ankh |
ANKH inorganic pyrophosphate transport regulator |
increases expression |
ISO |
nickel sulfate results in increased expression of ANKH mRNA |
CTD |
PMID:22714537 |
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NCBI chr 2:80,131,563...80,256,948
Ensembl chr 2:80,131,563...80,256,954
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Ankrd1 |
ankyrin repeat domain 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ANKRD1 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 1:254,726,985...254,745,673
Ensembl chr 1:254,726,969...254,735,548
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Ankrd6 |
ankyrin repeat domain 6 |
increases expression |
ISO |
nickel sulfate results in increased expression of ANKRD6 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 5:48,052,610...48,167,568
Ensembl chr 5:48,052,401...48,194,294
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Ano2 |
anoctamin 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ANO2 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 4:158,222,650...158,577,595
Ensembl chr 4:158,224,000...158,576,978
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Anpep |
alanyl aminopeptidase, membrane |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ANPEP mRNA |
CTD |
PMID:16166746 |
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NCBI chr 1:141,561,364...141,604,249
Ensembl chr 1:141,561,334...141,604,273
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Antxr1 |
ANTXR cell adhesion molecule 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of ANTXR1 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 4:118,946,267...119,131,202
Ensembl chr 4:118,946,268...119,131,202
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Antxr2 |
ANTXR cell adhesion molecule 2 |
increases expression decreases expression |
ISO |
nickel sulfate results in increased expression of ANTXR2 mRNA nickel sulfate results in decreased expression of ANTXR2 mRNA |
CTD |
PMID:16780908 PMID:22714537 |
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NCBI chr14:13,191,716...13,331,286
Ensembl chr14:13,192,347...13,274,978
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G |
Anxa1 |
annexin A1 |
increases expression |
ISO |
nickel sulfate results in increased expression of ANXA1 mRNA |
CTD |
PMID:16314067 |
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NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
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G |
Anxa2 |
annexin A2 |
increases expression |
ISO |
nickel sulfate results in increased expression of ANXA2 mRNA |
CTD |
PMID:16314067 |
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NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
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G |
Anxa3 |
annexin A3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ANXA3 mRNA |
CTD |
PMID:22714537 |
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NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
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G |
Aoc1 |
amine oxidase, copper containing 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of AOC1 mRNA |
CTD |
PMID:16780908 |
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NCBI chr 4:78,496,043...78,515,582
Ensembl chr 4:78,496,043...78,515,584
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G |
Aox1 |
aldehyde oxidase 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of AOX1 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 9:64,929,682...65,007,872
Ensembl chr 9:64,929,721...65,007,870
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G |
Ap1ar |
adaptor-related protein complex 1 associated regulatory protein |
decreases expression |
ISO |
nickel sulfate results in decreased expression of AP1AR mRNA |
CTD |
PMID:22714537 |
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NCBI chr 2:232,146,418...232,178,813
Ensembl chr 2:232,147,690...232,178,671
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G |
Apba2 |
amyloid beta precursor protein binding family A member 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of APBA2 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 1:125,367,273...125,547,741
Ensembl chr 1:125,367,280...125,548,890
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G |
Apmap |
adipocyte plasma membrane associated protein |
decreases expression |
ISO |
nickel sulfate results in decreased expression of APMAP mRNA |
CTD |
PMID:22714537 |
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NCBI chr 3:146,376,828...146,407,259
Ensembl chr 3:146,376,828...146,407,252
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G |
Apoe |
apolipoprotein E |
decreases expression increases expression |
ISO |
nickel sulfate results in decreased expression of APOE mRNA nickel sulfate results in increased expression of APOE mRNA |
CTD |
PMID:16780908 |
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NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
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G |
Aqp3 |
aquaporin 3 (Gill blood group) |
decreases expression |
ISO |
nickel sulfate results in decreased expression of AQP3 mRNA |
CTD |
PMID:16780908 PMID:20713136 |
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NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
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G |
Aqp9 |
aquaporin 9 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of AQP9 mRNA |
CTD |
PMID:18651567 |
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NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781
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G |
Ar |
androgen receptor |
increases expression |
ISO |
nickel sulfate results in increased expression of AR mRNA |
CTD |
PMID:22714537 |
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NCBI chr X:67,656,253...67,828,998
Ensembl chr X:67,656,253...67,829,026
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G |
Arap2 |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ARAP2 mRNA |
CTD |
PMID:22714537 |
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NCBI chr14:48,726,033...48,922,809
Ensembl chr14:48,726,045...48,922,983
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G |
Areg |
amphiregulin |
increases expression decreases expression |
ISO |
nickel sulfate results in increased expression of AREG mRNA nickel sulfate results in decreased expression of AREG mRNA |
CTD |
PMID:16166746 PMID:18651567 PMID:22714537 |
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NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
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G |
Arfip2 |
ADP-ribosylation factor interacting protein 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of ARFIP2 mRNA |
CTD |
PMID:18651567 |
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NCBI chr 1:170,464,995...170,471,138
Ensembl chr 1:170,466,395...170,471,076
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G |
Arg2 |
arginase 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of ARG2 mRNA |
CTD |
PMID:16314067 |
|
NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
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G |
Arhgap17 |
Rho GTPase activating protein 17 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ARHGAP17 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 1:193,239,036...193,328,425
Ensembl chr 1:193,239,040...193,328,371
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G |
Arhgap18 |
Rho GTPase activating protein 18 |
increases expression |
ISO |
nickel sulfate results in increased expression of ARHGAP18 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 1:19,227,115...19,463,139
Ensembl chr 1:19,227,121...19,376,301
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G |
Arhgap42 |
Rho GTPase activating protein 42 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ARHGAP42 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 8:7,210,999...7,446,215
Ensembl chr 8:7,213,822...7,426,611
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G |
Arhgap44 |
Rho GTPase activating protein 44 |
increases expression |
ISO |
nickel sulfate results in increased expression of ARHGAP44 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr10:51,501,547...51,669,546
Ensembl chr10:51,502,894...51,669,297
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G |
Arhgap5 |
Rho GTPase activating protein 5 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ARHGAP5 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 6:73,345,129...73,408,304
Ensembl chr 6:73,345,392...73,405,880
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G |
Arhgef9 |
Cdc42 guanine nucleotide exchange factor 9 |
multiple interactions |
EXP |
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of ARHGEF9 mRNA |
CTD |
PMID:31734292 |
|
NCBI chr X:64,249,576...64,428,444
Ensembl chr X:64,248,278...64,428,592
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G |
Arl10 |
ADP-ribosylation factor like GTPase 10 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ARL10 mRNA |
CTD |
PMID:22714537 |
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NCBI chr17:10,567,064...10,575,518
Ensembl chr17:10,568,959...10,575,203
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G |
Arl4c |
ADP ribosylation factor like GTPase 4C |
increases expression |
ISO |
nickel sulfate results in increased expression of ARL4C mRNA |
CTD |
PMID:17374397 PMID:18651567 |
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NCBI chr 9:95,783,651...95,787,092
Ensembl chr 9:95,786,508...95,787,094
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G |
Armcx1 |
armadillo repeat containing, X-linked 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ARMCX1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr X:105,535,670...105,539,575
Ensembl chr X:105,537,602...105,539,375 Ensembl chr X:105,537,602...105,539,375
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G |
Armcx2 |
armadillo repeat containing, X-linked 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ARMCX2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr X:105,617,383...105,622,209
Ensembl chr X:105,617,385...105,622,156
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G |
Armcx4 |
armadillo repeat containing, X-linked 4 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ARMCX4 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr X:105,497,277...105,507,636
Ensembl chr X:105,500,173...105,507,288
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G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
affects localization |
ISO |
nickel sulfate affects the localization of ARNT protein |
CTD |
PMID:17382205 |
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NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
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G |
Arnt2 |
aryl hydrocarbon receptor nuclear translocator 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of ARNT2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:146,399,217...146,556,437
Ensembl chr 1:146,399,217...146,556,171
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G |
Arpc2 |
actin related protein 2/3 complex, subunit 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of ARPC2 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 9:81,518,163...81,548,871
Ensembl chr 9:81,518,176...81,548,871
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G |
Arpc4 |
actin related protein 2/3 complex, subunit 4 |
increases expression |
ISO |
nickel sulfate results in increased expression of ARPC4 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr 4:145,330,457...145,340,985
Ensembl chr 4:145,330,457...145,340,984
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G |
Arrb1 |
arrestin, beta 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of ARRB1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139
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G |
Asah1 |
N-acylsphingosine amidohydrolase 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ASAH1 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr16:53,998,604...54,030,006
Ensembl chr16:53,998,560...54,040,836
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G |
Asgr1 |
asialoglycoprotein receptor 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ASGR1 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr10:56,662,188...56,666,086
Ensembl chr10:56,662,242...56,666,086
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G |
Asgr2 |
asialoglycoprotein receptor 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ASGR2 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr10:56,710,446...56,723,608
Ensembl chr10:56,710,464...56,723,611
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G |
Asmtl |
acetylserotonin O-methyltransferase-like |
increases expression |
ISO |
nickel sulfate results in increased expression of ASMTL mRNA |
CTD |
PMID:22714537 |
|
NCBI chr12:18,532,090...18,534,761
Ensembl chr12:18,531,990...18,534,836
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G |
Ass1 |
argininosuccinate synthase 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of ASS1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
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G |
Atat1 |
alpha tubulin acetyltransferase 1 |
multiple interactions |
EXP |
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of ATAT1 mRNA |
CTD |
PMID:31734292 |
|
NCBI chr20:3,351,269...3,364,565
Ensembl chr20:3,351,303...3,364,565
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G |
Atf3 |
activating transcription factor 3 |
increases expression |
ISO |
nickel sulfate results in increased expression of ATF3 mRNA |
CTD |
PMID:16314067 |
|
NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions |
EXP |
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of ATF6 mRNA |
CTD |
PMID:31734292 |
|
NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
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G |
Atl1 |
atlastin GTPase 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ATL1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 6:92,229,764...92,370,428
Ensembl chr 6:92,229,686...92,370,421
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G |
Atl3 |
atlastin GTPase 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ATL3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:222,746,023...222,788,439
Ensembl chr 1:222,746,023...222,786,942
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G |
Atp11a |
ATPase phospholipid transporting 11A |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ATP11A mRNA |
CTD |
PMID:22714537 |
|
NCBI chr16:81,990,340...82,100,222
Ensembl chr16:81,990,340...82,100,222
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G |
Atp1b1 |
ATPase Na+/K+ transporting subunit beta 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ATP1B1 mRNA |
CTD |
PMID:16100012 |
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NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
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G |
Atp1b3 |
ATPase Na+/K+ transporting subunit beta 3 |
increases expression decreases expression |
ISO |
nickel sulfate results in increased expression of ATP1B3 mRNA nickel sulfate results in decreased expression of ATP1B3 mRNA |
CTD |
PMID:16780908 PMID:18651567 |
|
NCBI chr 8:104,190,032...104,221,342
Ensembl chr 8:104,190,032...104,221,342
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G |
Atp2b4 |
ATPase plasma membrane Ca2+ transporting 4 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ATP2B4 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
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G |
Atp6v1a |
ATPase H+ transporting V1 subunit A |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ATP6V1A mRNA |
CTD |
PMID:18651567 |
|
NCBI chr11:61,531,386...61,584,634
Ensembl chr11:61,531,416...61,584,634
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G |
Atp8b2 |
ATPase phospholipid transporting 8B2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ATP8B2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:189,285,961...189,306,947
Ensembl chr 2:189,285,953...189,307,108
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G |
Atp9a |
ATPase phospholipid transporting 9A (putative) |
increases expression |
ISO |
nickel sulfate results in increased expression of ATP9A mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:165,405,588...165,511,104
Ensembl chr 3:165,412,803...165,477,771
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G |
Atrn |
attractin |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ATRN mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:123,434,409...123,567,922
Ensembl chr 3:123,434,409...123,567,918
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G |
Atxn1 |
ataxin 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of ATXN1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:19,160,986...19,533,814
Ensembl chr17:19,249,952...19,533,814
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G |
Atxn7l1 |
ataxin 7-like 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of ATXN7L1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 6:52,459,930...52,680,552
Ensembl chr 6:52,459,946...52,675,574
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G |
Auts2 |
activator of transcription and developmental regulator AUTS2 |
increases expression |
ISO |
nickel sulfate results in increased expression of AUTS2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr12:27,155,362...28,252,752
Ensembl chr12:28,212,333...28,251,816
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G |
Azin1 |
antizyme inhibitor 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of AZIN1 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 7:77,345,646...77,372,398
Ensembl chr 7:77,345,646...77,372,398
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G |
B3gat1 |
beta-1,3-glucuronyltransferase 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of B3GAT1 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 8:27,777,024...27,804,368
Ensembl chr 8:27,777,179...27,804,515
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G |
B3gnt5 |
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 |
increases expression |
ISO |
nickel sulfate results in increased expression of B3GNT5 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr11:84,919,055...84,931,160
Ensembl chr11:84,919,066...84,931,160
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G |
B4galnt1 |
beta-1,4-N-acetyl-galactosaminyl transferase 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of B4GALNT1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 7:70,439,273...70,459,556
Ensembl chr 7:70,452,579...70,459,880
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G |
Bach1 |
BTB domain and CNC homolog 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of BACH1 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr11:27,364,913...27,398,713
Ensembl chr11:27,364,916...27,398,842 Ensembl chr11:27,364,916...27,398,842
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G |
Baiap2l1 |
BAR/IMD domain containing adaptor protein 2 like 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of BAIAP2L1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr12:12,226,967...12,321,172
Ensembl chr12:12,227,010...12,321,172
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G |
Bak1 |
BCL2-antagonist/killer 1 |
multiple interactions increases expression |
EXP |
Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of BAK1 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of BAK1 protein]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of BAK1 mRNA]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of BAK1 protein] nickel sulfate results in increased expression of BAK1 mRNA; nickel sulfate results in increased expression of BAK1 protein |
CTD |
PMID:28296042 |
|
NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
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G |
Bambi |
BMP and activin membrane-bound inhibitor |
increases expression |
ISO |
nickel sulfate results in increased expression of BAMBI mRNA |
CTD |
PMID:20146380 |
|
NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression |
ISO |
sesamin inhibits the reaction [nickel sulfate results in increased expression of BAX protein] |
CTD |
PMID:23317420 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
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G |
Bbs5 |
Bardet-Biedl syndrome 5 |
increases expression |
ISO |
nickel sulfate results in increased expression of BBS5 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:55,886,695...55,907,717
Ensembl chr 3:55,886,695...55,907,716
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G |
Bcar1 |
BCAR1 scaffold protein, Cas family member |
decreases expression |
ISO |
nickel sulfate results in decreased expression of BCAR1 mRNA |
CTD |
PMID:16166746 |
|
NCBI chr19:43,932,543...43,967,452
Ensembl chr19:43,932,554...43,955,783
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G |
Bcl11a |
BAF chromatin remodeling complex subunit BCL11A |
decreases expression |
ISO |
nickel sulfate results in decreased expression of BCL11A mRNA |
CTD |
PMID:18651567 |
|
NCBI chr14:108,826,717...108,921,197
Ensembl chr14:108,826,831...108,921,669
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G |
Bcl2 |
BCL2, apoptosis regulator |
increases expression multiple interactions decreases expression |
ISO |
nickel sulfate results in increased expression of BCL2 protein sesamin inhibits the reaction [nickel sulfate results in decreased expression of BCL2 protein] |
CTD |
PMID:21776270 PMID:23317420 |
|
NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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G |
Bcl2a1 |
BCL2-related protein A1 |
increases expression |
ISO |
nickel sulfate results in increased expression of BCL2A1 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
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G |
Bcl2l1 |
Bcl2-like 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of BCL2L1 protein |
CTD |
PMID:21776270 |
|
NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
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G |
Bcl2l11 |
BCL2 like 11 |
increases expression |
ISO |
nickel sulfate results in increased expression of BCL2L11 mRNA |
CTD |
PMID:17382205 |
|
NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
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G |
Bcl9 |
BCL9, transcription coactivator |
increases expression |
ISO |
nickel sulfate results in increased expression of BCL9 mRNA |
CTD |
PMID:17382205 |
|
NCBI chr 2:199,334,644...199,420,083
Ensembl chr 2:199,334,664...199,354,793
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G |
Bdh1 |
3-hydroxybutyrate dehydrogenase 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of BDH1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr11:72,577,547...72,619,435
Ensembl chr11:72,578,533...72,614,176
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G |
Bex4 |
brain expressed, X-linked 4 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of BEX4 mRNA |
CTD |
PMID:22714537 |
|
|
|
G |
Bhlhe40 |
basic helix-loop-helix family, member e40 |
increases expression |
ISO |
nickel sulfate results in increased expression of BHLHE40 mRNA |
CTD |
PMID:18651567 PMID:22714537 |
|
NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
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G |
Bicc1 |
BicC family RNA binding protein 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of BICC1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr20:18,780,605...18,940,429
Ensembl chr20:18,780,605...18,940,408
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G |
Bid |
BH3 interacting domain death agonist |
increases expression |
ISO |
nickel sulfate results in increased expression of BID mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
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G |
Bin1 |
bridging integrator 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of BIN1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr18:25,163,575...25,222,139
Ensembl chr18:25,163,561...25,222,135
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G |
Birc2 |
baculoviral IAP repeat-containing 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of BIRC2 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
increases expression |
ISO |
nickel sulfate results in increased expression of BIRC3 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
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G |
Birc5 |
baculoviral IAP repeat-containing 5 |
multiple interactions |
ISO |
nickel sulfate affects the localization of and results in increased expression of BIRC5 protein |
CTD |
PMID:21776270 |
|
NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
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G |
Bmi1 |
BMI1 proto-oncogene, polycomb ring finger |
decreases expression |
ISO |
nickel sulfate results in decreased expression of BMI1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:85,360,439...85,370,283
Ensembl chr17:85,364,483...85,368,208
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G |
Bmp2 |
bone morphogenetic protein 2 |
multiple interactions |
EXP |
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of BMP2 mRNA |
CTD |
PMID:31734292 |
|
NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
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G |
Bmp4 |
bone morphogenetic protein 4 |
increases expression |
ISO |
nickel sulfate results in increased expression of BMP4 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
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G |
Bmp6 |
bone morphogenetic protein 6 |
increases expression |
ISO |
nickel sulfate results in increased expression of BMP6 mRNA |
CTD |
PMID:16780908 PMID:17374397 |
|
NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
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G |
Bmper |
BMP-binding endothelial regulator |
decreases expression |
ISO |
nickel sulfate results in decreased expression of BMPER mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 8:24,369,916...24,615,484
Ensembl chr 8:24,369,916...24,615,479
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G |
Bnip3 |
BCL2 interacting protein 3 |
increases expression |
ISO |
nickel sulfate results in increased expression of BNIP3 mRNA |
CTD |
PMID:17382205 |
|
NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
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G |
Brcc3 |
BRCA1/BRCA2-containing complex, subunit 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of BRCC3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 9:9,863,380...9,865,920
Ensembl chr 9:9,863,404...9,865,920
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G |
Brd2 |
bromodomain containing 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of BRD2 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr20:3,910,555...3,921,074
Ensembl chr20:3,910,555...3,917,426 Ensembl chr20:3,910,555...3,917,426
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G |
Bst2 |
bone marrow stromal cell antigen 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of BST2 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr16:19,938,781...19,942,353
Ensembl chr16:19,938,784...19,942,353
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G |
Btbd2 |
BTB domain containing 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of BTBD2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 7:11,929,859...11,943,559
Ensembl chr 7:11,930,135...11,942,799
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G |
Btbd3 |
BTB domain containing 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of BTBD3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:131,330,338...131,360,554
Ensembl chr 3:131,351,587...131,357,929
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G |
Btg1 |
BTG anti-proliferation factor 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of BTG1 mRNA |
CTD |
PMID:16780908 PMID:17374397 PMID:22714537 |
|
NCBI chr 7:37,812,831...37,815,088
Ensembl chr 7:37,812,831...37,815,088
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G |
Bub1 |
BUB1 mitotic checkpoint serine/threonine kinase |
decreases expression |
ISO |
nickel sulfate results in decreased expression of BUB1 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
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G |
C1qa |
complement C1q A chain |
decreases expression |
ISO |
nickel sulfate results in decreased expression of C1QA mRNA |
CTD |
PMID:25673294 |
|
NCBI chr 5:155,261,254...155,264,101
Ensembl chr 5:155,261,250...155,264,143
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G |
C1qb |
complement C1q B chain |
decreases expression |
ISO |
nickel sulfate results in decreased expression of C1QB mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 5:155,246,444...155,251,995
Ensembl chr 5:155,246,447...155,252,003
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G |
C1qc |
complement C1q C chain |
decreases expression |
ISO |
nickel sulfate results in decreased expression of C1QC mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 5:155,255,013...155,258,631
Ensembl chr 5:155,255,005...155,258,392
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G |
C1ql4 |
complement C1q like 4 |
increases expression |
ISO |
nickel sulfate results in increased expression of C1QL4 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 7:140,766,517...140,771,415
Ensembl chr 7:140,767,737...140,770,647
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G |
C1r |
complement C1r |
increases expression |
ISO |
nickel sulfate results in increased expression of C1R mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:157,126,060...157,136,825
Ensembl chr 4:157,125,998...157,136,829
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G |
C1s |
complement C1s |
increases expression |
ISO |
nickel sulfate results in increased expression of C1S mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:157,143,592...157,155,592
Ensembl chr 4:157,143,592...157,155,609
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G |
C5 |
complement C5 |
affects expression decreases expression |
ISO |
nickel sulfate affects the expression of HC mRNA nickel sulfate results in decreased expression of HC mRNA |
CTD |
PMID:12718980 PMID:16166746 |
|
NCBI chr 3:14,049,993...14,113,931 NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
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G |
Ca13 |
carbonic anhydrase 13 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CA13 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:88,282,961...88,314,254
Ensembl chr 2:88,282,961...88,314,254
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G |
Ca9 |
carbonic anhydrase 9 |
multiple interactions decreases expression increases expression |
ISO |
Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of CA9 protein] nickel sulfate results in decreased expression of CA9 mRNA |
CTD |
PMID:16288478 PMID:22714537 |
|
NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
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G |
Cables1 |
Cdk5 and Abl enzyme substrate 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of CABLES1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr18:3,317,724...3,421,721
Ensembl chr18:3,317,724...3,421,721
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G |
Cachd1 |
cache domain containing 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of CACHD1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 5:119,596,726...119,832,326
Ensembl chr 5:119,727,839...119,831,634
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G |
Cacna1i |
calcium voltage-gated channel subunit alpha1 I |
multiple interactions |
EXP |
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of CACNA1I mRNA |
CTD |
PMID:31734292 |
|
NCBI chr 7:121,521,787...121,619,300
Ensembl chr 7:121,511,097...121,619,283
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G |
Calcrl |
calcitonin receptor like receptor |
increases expression |
ISO |
nickel sulfate results in increased expression of CALCRL mRNA |
CTD |
PMID:16780908 PMID:17374397 |
|
NCBI chr 3:71,747,938...71,845,487
Ensembl chr 3:71,747,956...71,845,232
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G |
Camk1 |
calcium/calmodulin-dependent protein kinase I |
increases expression |
ISO |
nickel sulfate results in increased expression of CAMK1 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 4:145,289,300...145,300,146
Ensembl chr 4:145,288,996...145,300,177
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G |
Canx |
calnexin |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CANX mRNA |
CTD |
PMID:16780908 |
|
NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861
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G |
Caprin2 |
caprin family member 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of CAPRIN2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:183,304,993...183,374,195
Ensembl chr 4:183,305,813...183,374,195
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G |
Car2 |
carbonic anhydrase 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CA2 mRNA |
CTD |
PMID:16780908 PMID:17374397 |
|
NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
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G |
Card10 |
caspase recruitment domain family, member 10 |
increases expression |
ISO |
nickel sulfate results in increased expression of CARD10 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr 7:119,998,639...120,028,632
Ensembl chr 7:119,999,472...120,027,026
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G |
Carmil1 |
capping protein regulator and myosin 1 linker 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of CARMIL1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:43,050,282...43,339,403
Ensembl chr17:43,050,789...43,339,403
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G |
Cask |
calcium/calmodulin dependent serine protein kinase |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CASK mRNA |
CTD |
PMID:22714537 |
|
NCBI chr X:9,815,652...10,156,155
Ensembl chr X:9,815,652...10,156,155 Ensembl chr X:9,815,652...10,156,155
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G |
Casp12 |
caspase 12 |
increases expression multiple interactions |
EXP |
nickel sulfate results in increased expression of CASP12 mRNA; nickel sulfate results in increased expression of CASP12 protein Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP12 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP12 protein]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of CASP12 mRNA]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of CASP12 protein] |
CTD |
PMID:28296042 |
|
NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
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G |
Casp3 |
caspase 3 |
multiple interactions increases expression increases cleavage |
ISO EXP |
nickel sulfate inhibits the reaction [Potassium Dichromate results in increased cleavage of and results in increased activity of CASP3 protein]; nickel sulfate results in increased cleavage of and results in increased activity of CASP3 protein; Potassium Dichromate inhibits the reaction [nickel sulfate results in increased cleavage of and results in increased activity of CASP3 protein] nickel sulfate results in increased expression of CASP3 protein Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein] sesamin inhibits the reaction [nickel sulfate results in increased cleavage of CASP3 protein] |
CTD |
PMID:20493934 PMID:23317420 PMID:28296042 |
|
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
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G |
Casp9 |
caspase 9 |
multiple interactions increases expression |
EXP |
Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of CASP9 mRNA]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein] nickel sulfate results in increased expression of CASP9 mRNA; nickel sulfate results in increased expression of CASP9 protein |
CTD |
PMID:28296042 |
|
NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
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G |
Cat |
catalase |
increases expression multiple interactions decreases activity increases activity |
ISO EXP |
nickel sulfate results in increased expression of CAT mRNA sesamin inhibits the reaction [nickel sulfate results in decreased activity of CAT protein] nickel sulfate results in increased activity of CAT protein naringin inhibits the reaction [nickel sulfate results in decreased activity of CAT protein]; Zinc inhibits the reaction [nickel sulfate results in increased activity of CAT protein] |
CTD |
PMID:15535990 PMID:20566472 PMID:20950607 PMID:23317420 |
|
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
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G |
Cblb |
Cbl proto-oncogene B |
increases expression |
ISO |
nickel sulfate results in increased expression of CBLB mRNA |
CTD |
PMID:22714537 |
|
NCBI chr11:51,037,383...51,202,761
Ensembl chr11:51,037,393...51,202,820
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|
G |
Cbx2 |
chromobox 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of CBX2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr10:108,132,105...108,140,935
Ensembl chr10:108,132,105...108,140,935
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G |
Ccdc167 |
coiled-coil domain containing 167 |
increases expression |
ISO |
nickel sulfate results in increased expression of CCDC167 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr20:8,367,047...8,384,119
Ensembl chr20:8,369,331...8,384,088
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G |
Ccdc169 |
coiled-coil domain containing 169 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CCDC169 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:144,551,382...144,581,044
Ensembl chr 2:144,551,390...144,581,044
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G |
Ccdc18 |
coiled-coil domain containing 18 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CCDC18 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr14:1,664,620...1,701,269 NCBI chr14:2,510,184...2,612,070
Ensembl chr14:2,509,363...2,610,929
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G |
Ccdc189 |
coiled-coil domain containing 189 |
increases expression |
ISO |
nickel sulfate results in increased expression of CCDC189 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:199,032,105...199,037,267
Ensembl chr 1:199,032,105...199,037,267
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G |
Ccdc3 |
coiled-coil domain containing 3 |
increases expression |
ISO |
nickel sulfate results in increased expression of CCDC3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:76,991,722...77,093,515
Ensembl chr17:76,995,043...77,093,308
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G |
Ccdc68 |
coiled-coil domain containing 68 |
increases expression |
ISO |
nickel sulfate results in increased expression of CCDC68 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr18:68,408,812...68,472,323
Ensembl chr18:68,408,890...68,472,320
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G |
Ccdc80 |
coiled-coil domain containing 80 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CCDC80 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr11:60,645,660...60,679,249
Ensembl chr11:60,645,086...60,679,555
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G |
Ccdc88c |
coiled-coil domain containing 88C |
increases expression |
ISO |
nickel sulfate results in increased expression of CCDC88C mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 6:124,905,811...125,028,011
Ensembl chr 6:124,905,808...125,027,553
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G |
Ccl1 |
C-C motif chemokine ligand 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of CCL1 mRNA |
CTD |
PMID:11145678 |
|
NCBI chr10:69,534,976...69,537,836
Ensembl chr10:69,534,933...69,537,882
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G |
Ccl11 |
C-C motif chemokine ligand 11 |
decreases expression increases expression affects expression |
ISO |
nickel sulfate results in decreased expression of CCL11 mRNA nickel sulfate results in increased expression of CCL11 mRNA nickel sulfate affects the expression of CCL11 mRNA |
CTD |
PMID:16166746 PMID:18202158 PMID:18832182 |
|
NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
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G |
Ccl12 |
chemokine (C-C motif) ligand 12 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CCL13 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr10:69,476,866...69,478,416
Ensembl chr10:69,476,775...69,478,462
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G |
Ccl17 |
C-C motif chemokine ligand 17 |
affects expression increases expression |
ISO |
nickel sulfate affects the expression of CCL17 mRNA nickel sulfate results in increased expression of CCL17 mRNA |
CTD |
PMID:16166746 PMID:18202158 |
|
NCBI chr19:10,619,220...10,620,671
Ensembl chr19:10,619,220...10,620,671
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
decreases expression increases expression multiple interactions |
ISO |
nickel sulfate results in decreased expression of CCL2 mRNA nickel sulfate results in increased expression of CCL2 mRNA [macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of CCL2 mRNA |
CTD |
PMID:12060402 PMID:15585374 PMID:16100012 PMID:16166746 PMID:16780908 PMID:17374397 PMID:18832182 PMID:20713136 |
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NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
multiple interactions increases secretion |
ISO |
IL1A protein affects the reaction [nickel sulfate results in increased secretion of CCL20 protein]; TNF protein affects the reaction [nickel sulfate results in increased secretion of CCL20 protein] |
CTD |
PMID:15679580 PMID:16099135 |
|
NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
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G |
Ccl22 |
C-C motif chemokine ligand 22 |
affects expression increases expression |
ISO |
nickel sulfate affects the expression of CCL22 mRNA nickel sulfate results in increased expression of CCL22 mRNA |
CTD |
PMID:12060402 PMID:16166746 PMID:18202158 |
|
NCBI chr19:10,674,189...10,681,145
Ensembl chr19:10,674,189...10,681,145
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G |
Ccl27 |
C-C motif chemokine ligand 27 |
increases secretion |
ISO |
nickel sulfate results in increased secretion of CCL27 protein |
CTD |
PMID:15679580 |
|
NCBI chr 5:58,159,066...58,166,182
Ensembl chr 5:58,159,066...58,163,584
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G |
Ccl28 |
C-C motif chemokine ligand 28 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CCL28 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:52,379,341...52,403,979
Ensembl chr 2:52,379,341...52,404,246
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
affects expression increases expression |
ISO |
nickel sulfate affects the expression of CCL3 mRNA nickel sulfate results in increased expression of CCL3 mRNA |
CTD |
PMID:15585374 PMID:16780908 PMID:18202158 PMID:19732821 |
|
NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
increases expression increases secretion |
ISO |
nickel sulfate results in increased expression of CCL4 mRNA; nickel sulfate results in increased expression of CCL4 protein nickel sulfate results in increased secretion of CCL4 protein |
CTD |
PMID:12060402 PMID:15585374 PMID:16314067 PMID:16780908 PMID:18353026 PMID:20713136 |
|
NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
affects expression increases secretion |
ISO |
nickel sulfate affects the expression of CCL5 mRNA nickel sulfate results in increased secretion of CCL5 protein |
CTD |
PMID:16099135 PMID:18202158 |
|
NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
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G |
Ccl7 |
C-C motif chemokine ligand 7 |
increases expression |
ISO |
nickel sulfate results in increased expression of CCL7 mRNA |
CTD |
PMID:16166746 |
|
NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
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G |
Ccr1 |
C-C motif chemokine receptor 1 |
affects expression |
ISO |
nickel sulfate affects the expression of CCR1 mRNA |
CTD |
PMID:18202158 |
|
NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201
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G |
Ccr2 |
C-C motif chemokine receptor 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CCR2 mRNA |
CTD |
PMID:17374397 |
|
|
|
G |
Ccr6 |
C-C motif chemokine receptor 6 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CCR6 protein |
CTD |
PMID:15924226 |
|
NCBI chr 1:53,063,380...53,087,519
Ensembl chr 1:53,065,025...53,087,474
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G |
Ccr7 |
C-C motif chemokine receptor 7 |
affects expression increases expression |
ISO |
nickel sulfate affects the expression of CCR7 mRNA nickel sulfate results in increased expression of CCR7 mRNA |
CTD |
PMID:15304089 PMID:16780908 PMID:17374397 PMID:18202158 PMID:21697260 |
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NCBI chr10:87,057,335...87,067,444
Ensembl chr10:87,057,136...87,067,456
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G |
Ccr8 |
C-C motif chemokine receptor 8 |
affects expression increases expression |
ISO |
nickel sulfate affects the expression of CCR8 mRNA nickel sulfate results in increased expression of CCR8 mRNA |
CTD |
PMID:11145678 PMID:18202158 |
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NCBI chr 8:128,779,552...128,782,531
Ensembl chr 8:128,781,395...128,782,456
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G |
Cd200 |
Cd200 molecule |
decreases expression multiple interactions |
ISO EXP |
nickel sulfate results in decreased expression of CD200 mRNA [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of CD200 mRNA |
CTD |
PMID:22714537 PMID:31734292 |
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NCBI chr11:60,371,617...60,398,450
Ensembl chr11:60,371,684...60,403,196
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G |
Cd207 |
CD207 molecule |
multiple interactions decreases expression |
ISO |
pyrazolanthrone promotes the reaction [nickel sulfate results in decreased expression of CD207 protein] |
CTD |
PMID:15588916 |
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NCBI chr 4:115,333,124...115,355,034
Ensembl chr 4:115,348,491...115,354,795
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G |
Cd274 |
CD274 molecule |
increases expression decreases expression |
ISO |
nickel sulfate results in increased expression of CD274 protein nickel sulfate results in decreased expression of CD274 mRNA |
CTD |
PMID:22714537 PMID:25673294 |
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NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943
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G |
Cd276 |
Cd276 molecule |
increases expression |
ISO |
nickel sulfate results in increased expression of CD276 mRNA |
CTD |
PMID:16780908 |
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NCBI chr 8:63,312,060...63,350,411
Ensembl chr 8:63,318,019...63,350,269
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G |
Cd36 |
CD36 molecule |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CD36 mRNA |
CTD |
PMID:16780908 PMID:17374397 |
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NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
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G |
Cd40 |
CD40 molecule |
multiple interactions increases expression |
ISO |
BAY 11-7085 inhibits the reaction [nickel sulfate results in increased expression of CD40 protein] |
CTD |
PMID:17636246 PMID:25673294 |
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NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
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G |
Cd68 |
Cd68 molecule |
increases expression |
ISO |
nickel sulfate results in increased expression of CD68 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
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G |
Cd69 |
Cd69 molecule |
increases expression |
ISO |
nickel sulfate results in increased expression of CD69 mRNA |
CTD |
PMID:16780908 |
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NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084
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G |
Cd74 |
CD74 molecule |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CD74 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
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G |
Cd79a |
CD79a molecule |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CD79A mRNA |
CTD |
PMID:16166746 |
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NCBI chr 1:81,763,609...81,768,039
Ensembl chr 1:81,763,614...81,767,980
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G |
Cd80 |
Cd80 molecule |
increases expression |
ISO |
nickel sulfate results in increased expression of CD80 protein |
CTD |
PMID:25673294 |
|
NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353
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G |
Cd82 |
Cd82 molecule |
increases expression |
ISO |
nickel sulfate results in increased expression of CD82 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:82,324,344...82,368,846
Ensembl chr 3:82,324,354...82,368,357
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G |
Cd83 |
CD83 molecule |
increases expression multiple interactions |
ISO |
nickel sulfate results in increased expression of CD83 mRNA; nickel sulfate results in increased expression of CD83 protein BAY 11-7085 inhibits the reaction [nickel sulfate results in increased expression of CD83 protein]; lipopolysaccharide, E coli O55-B5 promotes the reaction [nickel sulfate results in increased expression of CD83 protein]; TNF protein promotes the reaction [nickel sulfate results in increased expression of CD83 protein] |
CTD |
PMID:16099135 PMID:16780908 PMID:17636246 PMID:21697260 PMID:25673294 |
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NCBI chr17:24,416,651...24,435,790
Ensembl chr17:24,416,651...24,435,790
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G |
Cd86 |
CD86 molecule |
increases expression affects expression multiple interactions |
ISO |
nickel sulfate results in increased expression of CD86 mRNA; nickel sulfate results in increased expression of CD86 protein nickel sulfate affects the expression of CD86 mRNA Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CD86 protein]; BAY 11-7085 inhibits the reaction [nickel sulfate results in increased expression of CD86 protein] |
CTD |
PMID:16099135 PMID:16780908 PMID:17374397 PMID:17636246 PMID:18202158 PMID:19033392 PMID:19665512 PMID:19702435 PMID:20417223 PMID:25673294 PMID:29540657 |
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NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
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G |
Cd8a |
CD8a molecule |
increases expression |
ISO |
nickel sulfate results in increased expression of CD8A mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 4:99,217,640...99,243,352
Ensembl chr 4:99,239,115...99,243,351
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G |
Cd99 |
CD99 molecule (Xg blood group) |
increases expression |
ISO |
nickel sulfate results in increased expression of CD99 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr20:56,192,426...56,196,961
Ensembl chr20:56,192,390...56,197,025
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G |
Cdc25b |
cell division cycle 25B |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CDC25B mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:123,731,539...123,741,696
Ensembl chr 3:123,731,539...123,741,339
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G |
Cdc34 |
cell division cycle 34, ubiqiutin conjugating enzyme |
increases expression |
ISO |
nickel sulfate results in increased expression of CDC34 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr 7:12,899,957...12,905,339
Ensembl chr 7:12,899,958...12,905,339
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G |
Cdh1 |
cadherin 1 |
decreases expression multiple interactions |
ISO |
nickel sulfate results in decreased expression of CDH1 mRNA; nickel sulfate results in decreased expression of CDH1 protein pyrazolanthrone promotes the reaction [nickel sulfate results in decreased expression of CDH1 protein] |
CTD |
PMID:15588916 PMID:16780908 PMID:22648416 |
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NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
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G |
Cdh13 |
cadherin 13 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CDH13 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103
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G |
Cdh16 |
cadherin 16 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CDH16 mRNA |
CTD |
PMID:16166746 |
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NCBI chr19:568,329...578,513
Ensembl chr19:568,287...578,520
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G |
Cdh3 |
cadherin 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CDH3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr19:38,668,957...38,719,801
Ensembl chr19:38,669,230...38,719,677
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G |
Cdh8 |
cadherin 8 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CDH8 mRNA |
CTD |
PMID:17374397 |
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NCBI chr19:6,031,654...6,431,502
Ensembl chr19:6,046,665...6,426,216
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G |
Cdk10 |
cyclin-dependent kinase 10 |
increases expression |
ISO |
nickel sulfate results in increased expression of CDK10 mRNA |
CTD |
PMID:22714537 |
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NCBI chr19:56,024,903...56,032,610
Ensembl chr19:56,024,903...56,032,605
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G |
Cdk14 |
cyclin-dependent kinase 14 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CDK14 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 4:25,825,567...26,419,443
Ensembl chr 4:25,825,567...26,419,127
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G |
Cdk6 |
cyclin-dependent kinase 6 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CDK6 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
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G |
Cdkl2 |
cyclin dependent kinase like 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of CDKL2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr14:17,530,170...17,565,950
Ensembl chr14:17,531,398...17,565,950
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G |
Cdkl5 |
cyclin-dependent kinase-like 5 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CDKL5 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr X:35,536,396...35,773,204
Ensembl chr X:35,599,258...35,771,711
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
ISO |
nickel sulfate results in increased expression of CDKN1A mRNA |
CTD |
PMID:16100012 PMID:16166746 PMID:16314067 |
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NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
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G |
Cdkn2d |
cyclin dependent kinase inhibitor 2D |
increases expression |
ISO |
nickel sulfate results in increased expression of CDKN2D mRNA |
CTD |
PMID:17382205 |
|
|
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G |
Cdo1 |
cysteine dioxygenase type 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CDO1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr18:40,702,027...40,716,901
Ensembl chr18:40,701,984...40,716,686
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G |
Cds2 |
CDP-diacylglycerol synthase 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CDS2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:124,896,657...124,935,221
Ensembl chr 3:124,896,618...124,935,226
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G |
Cdt1 |
chromatin licensing and DNA replication factor 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of CDT1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr19:55,381,565...55,386,511
Ensembl chr19:55,381,565...55,386,511
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G |
Cept1 |
choline/ethanolamine phosphotransferase 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CEPT1 mRNA |
CTD |
PMID:16780908 |
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NCBI chr 2:209,118,140...209,162,071
Ensembl chr 2:209,118,922...209,160,653
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G |
Cerkl |
ceramide kinase-like |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CERKL mRNA |
CTD |
PMID:17374397 |
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NCBI chr 3:66,268,835...66,395,615
Ensembl chr 3:66,268,947...66,394,764
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G |
Cers6 |
ceramide synthase 6 |
increases expression |
ISO |
nickel sulfate results in increased expression of LASS6 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 3:55,094,240...55,338,370
Ensembl chr 3:55,094,637...55,338,445
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G |
Cfap251 |
cilia and flagella associated protein 251 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CFAP251 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr12:38,708,915...38,781,598
Ensembl chr12:38,709,595...38,782,010
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G |
Cfap44 |
cilia and flagella associated protein 44 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CFAP44 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr11:61,160,793...61,237,056
Ensembl chr11:61,162,628...61,234,944
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G |
Cfap69 |
cilia and flagella associated protein 69 |
increases expression |
ISO |
nickel sulfate results in increased expression of CFAP69 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:25,538,513...25,611,470
Ensembl chr 4:25,538,497...25,609,652
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G |
Cflar |
CASP8 and FADD-like apoptosis regulator |
increases expression |
ISO |
nickel sulfate results in increased expression of CFLAR mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
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G |
Cga |
glycoprotein hormones, alpha polypeptide |
increases expression multiple interactions |
ISO EXP |
nickel sulfate results in increased expression of CGA mRNA [CGA protein co-treated with nickel sulfate] results in decreased expression of CYP11A1 mRNA; [CGA protein co-treated with nickel sulfate] results in decreased expression of CYP11A1 protein; [CGA protein co-treated with nickel sulfate] results in decreased expression of CYP17A1 mRNA; [CGA protein co-treated with nickel sulfate] results in decreased expression of CYP17A1 protein; [CGA protein co-treated with nickel sulfate] results in decreased expression of HSD17B3 mRNA; [CGA protein co-treated with nickel sulfate] results in decreased expression of STAR mRNA; [CGA protein co-treated with nickel sulfate] results in decreased expression of STAR protein |
CTD |
PMID:18651567 PMID:29567110 |
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NCBI chr 5:50,362,491...50,393,368
Ensembl chr 5:50,381,244...50,393,367
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G |
Chd1l |
chromodomain helicase DNA binding protein 1-like |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CHD1L mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:199,714,044...199,792,270
Ensembl chr 2:199,716,713...199,771,896
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G |
Chka |
choline kinase alpha |
increases expression |
ISO |
nickel sulfate results in increased expression of CHKA mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 1:219,076,618...219,126,221
Ensembl chr 1:219,077,771...219,126,220
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G |
Chmp1a |
charged multivesicular body protein 1A |
increases expression |
ISO |
nickel sulfate results in increased expression of CHMP1A mRNA |
CTD |
PMID:22714537 |
|
NCBI chr19:56,001,724...56,010,004
Ensembl chr19:56,001,724...56,010,004
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G |
Chrdl1 |
chordin-like 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CHRDL1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr X:114,554,359...114,658,975
Ensembl chr X:114,554,359...114,658,931
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G |
Chst11 |
carbohydrate sulfotransferase 11 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CHST11 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 7:26,641,856...26,890,503
Ensembl chr 7:26,645,422...26,859,716
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G |
Chst15 |
carbohydrate sulfotransferase 15 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CHST15 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:204,243,396...204,328,960
Ensembl chr 1:204,245,645...204,322,544
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G |
Cidea |
cell death-inducing DFFA-like effector a |
multiple interactions decreases expression |
ISO |
[nickel sulfate co-treated with Particulate Matter] results in decreased expression of CIDEA mRNA nickel sulfate results in decreased expression of CIDEA mRNA |
CTD |
PMID:23126276 |
|
NCBI chr18:63,082,861...63,108,450
Ensembl chr18:63,098,144...63,108,051
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G |
Cidec |
cell death-inducing DFFA-like effector c |
increases expression |
ISO |
nickel sulfate results in increased expression of CIDEC mRNA |
CTD |
PMID:16780908 PMID:17374397 |
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NCBI chr 4:145,377,482...145,390,497
Ensembl chr 4:145,377,431...145,390,497
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G |
Cisd1 |
CDGSH iron sulfur domain 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CISD1 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr20:18,493,538...18,506,923
Ensembl chr20:18,493,538...18,506,912
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G |
Cited2 |
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CITED2 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
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G |
Ckb |
creatine kinase B |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CKB mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
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G |
Clcn4 |
chloride voltage-gated channel 4 |
increases expression |
ISO |
nickel sulfate results in increased expression of CLCN4 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr X:25,016,177...25,082,563
Ensembl chr X:25,016,401...25,080,410
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G |
Cldn11 |
claudin 11 |
increases expression |
ISO |
nickel sulfate results in increased expression of CLDN11 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:115,823,541...115,836,846
Ensembl chr 2:115,823,538...115,836,846
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G |
Clic4 |
chloride intracellular channel 4 |
increases expression |
ISO |
nickel sulfate results in increased expression of CLIC4 mRNA |
CTD |
PMID:16314067 |
|
NCBI chr 5:153,568,937...153,625,669
Ensembl chr 5:153,568,745...153,625,869
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G |
Clip2 |
CAP-GLY domain containing linker protein 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of CLIP2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr12:25,172,957...25,236,935
Ensembl chr12:25,173,005...25,237,009
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G |
Cltb |
clathrin, light chain B |
decreases expression increases expression |
ISO |
nickel sulfate results in decreased expression of CLTB mRNA nickel sulfate results in increased expression of CLTB mRNA |
CTD |
PMID:16780908 PMID:18651567 |
|
NCBI chr17:10,537,348...10,554,999
Ensembl chr17:10,537,365...10,554,989
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G |
Cmbl |
carboxymethylenebutenolidase homolog |
increases expression |
ISO |
nickel sulfate results in increased expression of CMBL mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:84,645,084...84,666,836
Ensembl chr 2:84,645,084...84,666,835
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G |
Cmip |
c-Maf-inducing protein |
increases expression |
ISO |
nickel sulfate results in increased expression of CMIP mRNA |
CTD |
PMID:22714537 |
|
NCBI chr19:49,792,273...50,000,535
Ensembl chr19:49,792,273...50,000,535
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G |
Cmpk2 |
cytidine/uridine monophosphate kinase 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CMPK2 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 6:45,683,242...45,694,824
Ensembl chr 6:45,683,234...45,694,822
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G |
Cnn1 |
calponin 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CNN1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 8:23,113,083...23,121,748
Ensembl chr 8:23,113,048...23,121,761
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G |
Cnnm1 |
cyclin and CBS domain divalent metal cation transport mediator 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CNNM1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:263,184,361...263,243,912
Ensembl chr 1:263,186,235...263,242,468
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G |
Cntnap1 |
contactin associated protein 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CNTNAP1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr10:89,087,904...89,103,615
Ensembl chr10:89,089,646...89,103,614
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G |
Cntnap3 |
contactin associated protein family member 3 |
increases expression |
ISO |
nickel sulfate results in increased expression of CNTNAP3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:2,197,355...2,380,727
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|
G |
Coch |
cochlin |
decreases expression |
ISO |
nickel sulfate results in decreased expression of COCH mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 6:72,359,702...72,373,710
Ensembl chr 6:72,359,791...72,373,695
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G |
Col12a1 |
collagen type XII alpha 1 chain |
decreases expression |
ISO |
nickel sulfate results in decreased expression of COL12A1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 8:87,042,820...87,150,701
Ensembl chr 8:87,040,799...87,158,368
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G |
Col15a1 |
collagen type XV alpha 1 chain |
decreases expression |
ISO |
nickel sulfate results in decreased expression of COL15A1 mRNA |
CTD |
PMID:16166746 |
|
NCBI chr 5:62,840,360...62,950,240
Ensembl chr 5:64,476,317...64,542,645 Ensembl chr 5:64,476,317...64,542,645
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G |
Col16a1 |
collagen type XVI alpha 1 chain |
increases expression |
ISO |
nickel sulfate results in increased expression of COL16A1 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr 5:148,257,030...148,311,645
Ensembl chr 5:148,257,642...148,311,645
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G |
Col1a1 |
collagen type I alpha 1 chain |
decreases expression |
ISO |
nickel sulfate results in decreased expression of COL1A1 mRNA |
CTD |
PMID:16166746 |
|
NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
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G |
Col3a1 |
collagen type III alpha 1 chain |
decreases expression |
ISO |
nickel sulfate results in decreased expression of COL3A1 mRNA |
CTD |
PMID:16166746 |
|
NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
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G |
Col4a1 |
collagen type IV alpha 1 chain |
decreases expression |
ISO |
nickel sulfate results in decreased expression of COL4A1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
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G |
Col4a4 |
collagen type IV alpha 4 chain |
multiple interactions |
EXP |
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of COL4A4 mRNA |
CTD |
PMID:31734292 |
|
NCBI chr 9:88,314,763...88,357,183
Ensembl chr 9:88,232,455...88,357,182
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|
G |
Col4a5 |
collagen type IV alpha 5 chain |
decreases expression |
ISO |
nickel sulfate results in decreased expression of COL4A5 mRNA |
CTD |
PMID:16166746 |
|
NCBI chr X:112,769,595...112,983,720
Ensembl chr X:112,769,645...112,983,685
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G |
Col5a1 |
collagen type V alpha 1 chain |
decreases expression |
ISO |
nickel sulfate results in decreased expression of COL5A1 mRNA |
CTD |
PMID:16166746 |
|
NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
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G |
Col5a2 |
collagen type V alpha 2 chain |
increases expression |
ISO |
nickel sulfate results in increased expression of COL5A2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564
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|
G |
Col6a3 |
collagen type VI alpha 3 chain |
decreases expression |
ISO |
nickel sulfate results in decreased expression of COL6A3 mRNA |
CTD |
PMID:16166746 |
|
NCBI chr 9:97,926,784...98,004,643
Ensembl chr 9:97,926,787...98,004,546
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G |
Col8a1 |
collagen type VIII alpha 1 chain |
decreases expression |
ISO |
nickel sulfate results in decreased expression of COL8A1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr11:44,877,690...45,006,203
Ensembl chr11:44,877,859...45,007,891
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|
G |
Commd3 |
COMM domain containing 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of COMMD3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:85,356,042...85,359,835
Ensembl chr17:85,356,042...85,359,833
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G |
Comt |
catechol-O-methyltransferase |
increases expression |
ISO |
nickel sulfate results in increased expression of COMT mRNA |
CTD |
PMID:18651567 |
|
NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
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|
G |
Coro2b |
coronin 2B |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CORO2B mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 8:67,374,617...67,492,490
Ensembl chr 8:67,376,294...67,492,037
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|
G |
Cpe |
carboxypeptidase E |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CPE mRNA |
CTD |
PMID:22714537 |
|
NCBI chr16:26,906,716...27,014,811
Ensembl chr16:26,906,716...27,014,813
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|
G |
Cpeb3 |
cytoplasmic polyadenylation element binding protein 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CPEB3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:255,660,165...255,842,671
Ensembl chr 1:255,665,238...255,815,733
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|
G |
Cpne3 |
copine 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CPNE3 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 5:33,525,307...33,574,610
Ensembl chr 5:33,528,154...33,574,596
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|
G |
Cpped1 |
calcineurin-like phosphoesterase domain containing 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of CPPED1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr10:3,655,038...3,774,887
Ensembl chr10:3,655,038...3,774,884
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|
G |
Cpq |
carboxypeptidase Q |
increases expression |
ISO |
nickel sulfate results in increased expression of PGCP mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 7:71,709,174...72,167,413
Ensembl chr 7:71,709,157...72,167,417
|
|
G |
Cpt1c |
carnitine palmitoyltransferase 1c |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CPT1C mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:100,955,094...100,970,579
Ensembl chr 1:100,955,095...100,969,560
|
|
G |
Cpvl |
carboxypeptidase, vitellogenic-like |
increases expression |
ISO |
nickel sulfate results in increased expression of CPVL mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:84,026,851...84,137,172
Ensembl chr 4:84,025,926...84,131,030
|
|
G |
Crabp2 |
cellular retinoic acid binding protein 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CRABP2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:187,322,416...187,326,794
Ensembl chr 2:184,882,969...184,883,505
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|
G |
Creb1 |
cAMP responsive element binding protein 1 |
affects expression multiple interactions increases phosphorylation |
ISO |
nickel sulfate affects the expression of CREB1 mRNA puerarin inhibits the reaction [nickel sulfate results in increased phosphorylation of CREB1 protein] [nickel sulfate co-treated with Dinoprostone] results in increased expression of CREB1 protein; CREB1 protein promotes the reaction [[nickel sulfate co-treated with Dinoprostone] results in increased secretion of CXCL8 protein] |
CTD |
PMID:20385217 PMID:23526216 PMID:26607348 |
|
NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
|
|
G |
Creb5 |
cAMP responsive element binding protein 5 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CREB5 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:83,390,782...83,840,356
Ensembl chr 4:83,391,283...83,836,351
|
|
G |
Crem |
cAMP responsive element modulator |
increases expression |
ISO |
nickel sulfate results in increased expression of CREM mRNA |
CTD |
PMID:16780908 PMID:17374397 |
|
NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
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|
G |
Crim1 |
cysteine rich transmembrane BMP regulator 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of CRIM1 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 6:788,490...962,663
Ensembl chr 6:788,548...960,703
|
|
G |
Crls1 |
cardiolipin synthase 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CRLS1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:125,503,638...125,522,460
Ensembl chr 3:125,503,638...125,522,441
|
|
G |
Crnkl1 |
crooked neck pre-mRNA splicing factor 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CRNKL1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 6:18,349,226...18,351,540
Ensembl chr 6:18,349,167...18,351,536
|
|
G |
Crybg3 |
crystallin beta-gamma domain containing 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CRYBG3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr11:42,895,610...43,006,568
Ensembl chr11:42,945,084...43,005,097
|
|
G |
Csf2rb |
colony stimulating factor 2 receptor subunit beta |
affects expression |
ISO |
nickel sulfate affects the expression of CSF2RB mRNA |
CTD |
PMID:18202158 |
|
NCBI chr 7:119,554,383...119,568,248
Ensembl chr 7:119,554,354...119,568,776
|
|
G |
Csf3r |
colony stimulating factor 3 receptor |
increases expression |
ISO |
nickel sulfate results in increased expression of CSF3R mRNA |
CTD |
PMID:17382205 |
|
NCBI chr 5:144,031,353...144,051,966
Ensembl chr 5:144,031,402...144,051,600
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|
G |
Csnk2a1 |
casein kinase 2 alpha 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CSNK2A1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:147,713,808...147,760,375
Ensembl chr 3:147,713,821...147,757,862
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|
G |
Cspg4 |
chondroitin sulfate proteoglycan 4 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CSPG4 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 8:61,532,465...61,567,510
Ensembl chr 8:61,532,465...61,567,510
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|
G |
Csta |
cystatin A |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CSTA mRNA |
CTD |
PMID:18651567 |
|
NCBI chr11:67,555,792...67,566,980
Ensembl chr11:67,555,658...67,566,972
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|
G |
Cth |
cystathionine gamma-lyase |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CTH mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
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|
G |
Ctnnal1 |
catenin alpha-like 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CTNNAL1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 5:73,561,249...73,621,070
Ensembl chr 5:73,561,450...73,621,070
|
|
G |
Ctps1 |
CTP synthase 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of CTPS1 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 5:139,475,934...139,505,065
Ensembl chr 5:139,475,934...139,505,065
|
|
G |
Ctsb |
cathepsin B |
increases expression |
ISO |
nickel sulfate results in increased expression of CTSB mRNA |
CTD |
PMID:16314067 |
|
NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
|
|
G |
Ctsc |
cathepsin C |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CTSC mRNA |
CTD |
PMID:16780908 PMID:17374397 PMID:22714537 PMID:25673294 |
|
NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
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|
G |
Ctsf |
cathepsin F |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CTSF mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:220,114,228...220,119,976
Ensembl chr 1:220,114,228...220,119,976
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|
G |
Ctsl |
cathepsin L |
increases expression decreases expression |
ISO |
nickel sulfate results in increased expression of CTSL mRNA nickel sulfate results in decreased expression of CTSL mRNA |
CTD |
PMID:16780908 PMID:17374397 |
|
NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
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|
G |
Cul4b |
cullin 4B |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CUL4B mRNA |
CTD |
PMID:16100012 |
|
NCBI chr X:124,831,391...124,870,329
Ensembl chr X:124,832,628...124,870,329
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|
G |
Cxadr |
CXADR, Ig-like cell adhesion molecule |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CXADR mRNA |
CTD |
PMID:22714537 |
|
NCBI chr11:16,826,269...16,873,564
Ensembl chr11:16,826,399...16,873,562
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|
G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
multiple interactions increases expression |
ISO |
HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of CXCL1 protein]; macrophage stimulatory lipopeptide 2 promotes the reaction [nickel sulfate results in increased expression of CXCL1 mRNA]; nickel sulfate promotes the reaction [macrophage stimulatory lipopeptide 2 results in increased expression of CXCL1 mRNA]; nickel sulfate promotes the reaction [macrophage stimulatory lipopeptide 2 results in increased secretion of CXCL1 protein]; PTGS2 protein promotes the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of CXCL1 protein] |
CTD |
PMID:16780908 PMID:18832182 |
|
NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
|
|
G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
increases expression decreases expression multiple interactions |
ISO |
nickel sulfate results in increased expression of CXCL10 mRNA nickel sulfate results in decreased expression of CXCL10 mRNA [macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of CXCL10 mRNA; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [nickel sulfate inhibits the reaction [macrophage stimulatory lipopeptide 2 results in increased secretion of CXCL10 protein]]; nickel sulfate inhibits the reaction [macrophage stimulatory lipopeptide 2 results in increased expression of CXCL10 mRNA]; nickel sulfate inhibits the reaction [macrophage stimulatory lipopeptide 2 results in increased secretion of CXCL10 protein] |
CTD |
PMID:12060402 PMID:18096868 PMID:18832182 PMID:23445166 |
|
NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
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|
G |
Cxcl16 |
C-X-C motif chemokine ligand 16 |
increases expression |
ISO |
nickel sulfate results in increased expression of CXCL16 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr10:57,060,005...57,064,600
Ensembl chr10:57,060,007...57,064,600
|
|
G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
affects expression increases expression |
ISO EXP |
nickel sulfate affects the expression of CXCL2 mRNA nickel sulfate results in increased expression of CXCL2 mRNA |
CTD |
PMID:11708899 PMID:18202158 |
|
NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
|
|
G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions increases expression |
ISO |
HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of CXCL1 protein]; macrophage stimulatory lipopeptide 2 promotes the reaction [nickel sulfate results in increased expression of CXCL1 mRNA]; nickel sulfate promotes the reaction [macrophage stimulatory lipopeptide 2 results in increased expression of CXCL1 mRNA]; nickel sulfate promotes the reaction [macrophage stimulatory lipopeptide 2 results in increased secretion of CXCL1 protein]; PTGS2 protein promotes the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of CXCL1 protein] |
CTD |
PMID:16166746 PMID:16780908 PMID:18832182 |
|
NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
|
|
G |
Cxcl6 |
C-X-C motif chemokine ligand 6 |
multiple interactions |
ISO |
nickel sulfate promotes the reaction [macrophage stimulatory lipopeptide 2 results in increased expression of CXCL6 mRNA] |
CTD |
PMID:18832182 |
|
NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
|
|
G |
Cxcr4 |
C-X-C motif chemokine receptor 4 |
decreases expression increases expression affects expression |
ISO |
nickel sulfate results in decreased expression of CXCR4 protein nickel sulfate results in increased expression of CXCR4 mRNA nickel sulfate affects the expression of CXCR4 mRNA |
CTD |
PMID:15924226 PMID:16780908 PMID:17374397 PMID:17382205 PMID:18202158 |
|
NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
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|
G |
Cyba |
cytochrome b-245 alpha chain |
increases expression |
ISO |
nickel sulfate results in increased expression of CYBA mRNA |
CTD |
PMID:22714537 |
|
NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
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|
G |
Cycs |
cytochrome c, somatic |
increases expression multiple interactions |
EXP |
nickel sulfate results in increased expression of CYCS mRNA Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CYCS mRNA]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of CYCS mRNA] |
CTD |
PMID:28296042 |
|
NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
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|
G |
Cygb |
cytoglobin |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CYGB mRNA |
CTD |
PMID:22714537 |
|
NCBI chr10:105,618,325...105,628,091
Ensembl chr10:105,618,326...105,628,091
|
|
G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
decreases expression multiple interactions |
EXP |
nickel sulfate results in decreased expression of CYP11A1 mRNA; nickel sulfate results in decreased expression of CYP11A1 protein [CGA protein co-treated with nickel sulfate] results in decreased expression of CYP11A1 mRNA; [CGA protein co-treated with nickel sulfate] results in decreased expression of CYP11A1 protein; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 protein]; pyrazolanthrone inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 mRNA]; pyrazolanthrone inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 protein]; SB 203580 inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 mRNA]; SB 203580 inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 protein]; U 0126 inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 mRNA]; U 0126 inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 protein] |
CTD |
PMID:29567110 |
|
NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
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|
G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
multiple interactions decreases expression |
EXP |
[CGA protein co-treated with nickel sulfate] results in decreased expression of CYP17A1 mRNA; [CGA protein co-treated with nickel sulfate] results in decreased expression of CYP17A1 protein; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 protein]; pyrazolanthrone inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 mRNA]; pyrazolanthrone inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 protein]; SB 203580 inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 mRNA]; SB 203580 inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 protein]; U 0126 inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 mRNA]; U 0126 inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 protein] nickel sulfate results in decreased expression of CYP17A1 mRNA; nickel sulfate results in decreased expression of CYP17A1 protein |
CTD |
PMID:29567110 |
|
NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
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|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression decreases expression |
ISO |
nickel sulfate results in increased expression of CYP1A1 mRNA nickel sulfate results in decreased expression of CYP1A1 mRNA |
CTD |
PMID:20491607 PMID:20713136 |
|
NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
|
|
G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
decreases expression multiple interactions |
ISO EXP |
nickel sulfate results in decreased expression of CYP1B1 mRNA [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of CYP1B1 mRNA |
CTD |
PMID:22714537 PMID:31734292 |
|
NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
|
|
G |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
decreases expression multiple interactions increases expression |
ISO EXP |
nickel sulfate results in decreased expression of CYP27A1 mRNA [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of CYP27A1 mRNA nickel sulfate results in increased expression of CYP27A1 mRNA |
CTD |
PMID:20713136 PMID:22714537 PMID:31734292 |
|
NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
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|
G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CYP2B10 mRNA |
CTD |
PMID:16100012 |
|
NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
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|
G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CYP2B9 mRNA |
CTD |
PMID:16100012 |
|
NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
|
|
G |
Cyp2f4 |
cytochrome P450, family 2, subfamily f, polypeptide 4 |
affects expression decreases expression |
ISO |
nickel sulfate affects the expression of CYP2F2 mRNA nickel sulfate results in decreased expression of CYP2F2 mRNA |
CTD |
PMID:12718980 PMID:16100012 |
|
NCBI chr 1:83,933,974...83,947,804
Ensembl chr 1:83,933,942...83,947,821
|
|
G |
Cyp2u1 |
cytochrome P450, family 2, subfamily u, polypeptide 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of CYP2U1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:236,414,131...236,431,650
Ensembl chr 2:236,414,135...236,431,683
|
|
G |
Cytip |
cytohesin 1 interacting protein |
increases expression |
ISO |
nickel sulfate results in increased expression of CYTIP mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 3:44,150,494...44,225,723
Ensembl chr 3:44,150,992...44,177,689
|
|
G |
Dab1 |
DAB adaptor protein 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of DAB1 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 5:123,154,360...124,279,170
Ensembl chr 5:123,905,166...124,280,115
|
|
G |
Dact1 |
dishevelled-binding antagonist of beta-catenin 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DACT1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 6:93,740,440...93,751,003
Ensembl chr 6:93,740,586...93,749,809
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|
G |
Dapk1 |
death associated protein kinase 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DAPK1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:4,297,038...4,454,941
Ensembl chr17:4,297,224...4,454,778
|
|
G |
Dcbld2 |
discoidin, CUB and LCCL domain containing 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DCBLD2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr11:44,237,814...44,292,884
Ensembl chr11:44,241,111...44,292,884
|
|
G |
Dclk2 |
doublecortin-like kinase 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of DCLK2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:186,116,624...186,245,937
Ensembl chr 2:186,116,624...186,245,771
|
|
G |
Dct |
dopachrome tautomerase |
increases expression |
ISO |
nickel sulfate results in increased expression of DCT mRNA |
CTD |
PMID:16780908 |
|
NCBI chr15:103,208,174...103,245,033
Ensembl chr15:103,208,258...103,244,494
|
|
G |
Dctpp1 |
dCTP pyrophosphatase 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DCTPP1 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 1:198,703,459...198,706,852
Ensembl chr 1:198,703,461...198,706,852
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G |
Ddah2 |
dimethylarginine dimethylaminohydrolase 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of DDAH2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr20:5,049,260...5,052,573
Ensembl chr20:5,049,496...5,052,585
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions increases expression |
EXP |
Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of DDIT3 protein]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of DDIT3 mRNA]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of DDIT3 protein] nickel sulfate results in increased expression of DDIT3 mRNA; nickel sulfate results in increased expression of DDIT3 protein |
CTD |
PMID:28296042 |
|
NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
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G |
Ddit4 |
DNA-damage-inducible transcript 4 |
increases expression |
ISO |
nickel sulfate results in increased expression of DDIT4 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
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G |
Ddo |
D-aspartate oxidase |
increases expression |
ISO |
nickel sulfate results in increased expression of DDO mRNA |
CTD |
PMID:22714537 |
|
NCBI chr20:48,739,812...48,758,958
Ensembl chr20:48,739,639...48,758,905
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G |
Ddr1 |
discoidin domain receptor tyrosine kinase 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of DDR1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr20:3,553,430...3,574,959
Ensembl chr20:3,552,929...3,575,780
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G |
Ddr2 |
discoidin domain receptor tyrosine kinase 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of DDR2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr13:88,311,639...88,436,561
Ensembl chr13:88,317,145...88,436,789
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G |
Ddrgk1 |
DDRGK domain containing 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DDRGK1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:123,195,580...123,206,828
Ensembl chr 3:123,195,580...123,206,828
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G |
Ddx17 |
DEAD-box helicase 17 |
multiple interactions |
EXP |
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of DDX17 mRNA |
CTD |
PMID:31734292 |
|
NCBI chr 7:120,761,843...120,765,012
Ensembl chr 7:120,761,826...120,780,641
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G |
Ddx39b |
DExD-box helicase 39B |
multiple interactions |
EXP |
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of DDX39B mRNA |
CTD |
PMID:31734292 |
|
NCBI chr20:4,806,103...4,818,600
Ensembl chr20:4,806,108...4,818,568
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G |
Deaf1 |
DEAF1 transcription factor |
increases expression |
ISO |
nickel sulfate results in increased expression of DEAF1 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 1:214,283,787...214,317,466
Ensembl chr 1:214,283,790...214,317,466
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G |
Def8 |
differentially expressed in FDCP 8 homolog |
increases expression |
ISO |
nickel sulfate results in increased expression of DEF8 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr19:56,238,353...56,259,867
Ensembl chr19:56,243,408...56,259,196
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G |
Dennd1b |
DENN domain containing 1B |
increases expression |
ISO |
nickel sulfate results in increased expression of DENND1B mRNA |
CTD |
PMID:22714537 |
|
NCBI chr13:56,015,813...56,242,041
Ensembl chr13:56,015,901...56,236,677
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G |
Dennd2d |
DENN domain containing 2D |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DENND2D mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:209,097,894...209,116,978
Ensembl chr 2:209,097,927...209,116,965
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G |
Depp1 |
DEPP1, autophagy regulator |
increases expression |
ISO |
nickel sulfate results in increased expression of DEPP1 mRNA |
CTD |
PMID:16780908 PMID:17382205 |
|
NCBI chr 4:148,780,330...148,784,566
Ensembl chr 4:148,782,479...148,784,562
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G |
Dgka |
diacylglycerol kinase, alpha |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DGKA mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 7:3,143,826...3,170,764
Ensembl chr 7:3,143,827...3,170,146
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G |
Dgkh |
diacylglycerol kinase, eta |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DGKH mRNA |
CTD |
PMID:22714537 |
|
NCBI chr15:60,791,574...60,967,236
Ensembl chr15:60,803,098...60,959,769
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G |
Dgki |
diacylglycerol kinase, iota |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DGKI mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:64,365,115...64,831,473
Ensembl chr 4:64,374,342...64,831,473
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G |
Dhrs11 |
dehydrogenase/reductase 11 |
increases expression |
ISO |
nickel sulfate results in increased expression of DHRS11 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr10:72,144,042...72,153,496
Ensembl chr10:72,144,042...72,153,375
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G |
Diaph2 |
diaphanous-related formin 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DIAPH2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr X:99,722,910...100,363,228
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|
G |
Dio2 |
iodothyronine deiodinase 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of DIO2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
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G |
Dkc1 |
dyskerin pseudouridine synthase 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DKC1 mRNA |
CTD |
PMID:16780908 PMID:17374397 |
|
NCBI chr X:155,844,914...155,862,363
Ensembl chr X:155,844,857...155,862,475
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G |
Dlx1 |
distal-less homeobox 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of DLX1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:58,164,931...58,169,521
Ensembl chr 3:58,164,931...58,169,521
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G |
Dlx2 |
distal-less homeobox 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of DLX2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:58,180,088...58,181,971
Ensembl chr 3:58,180,088...58,181,971
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G |
Dnaaf9 |
dynein axonemal assembly factor 9 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DNAAF9 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:123,243,873...123,376,458
Ensembl chr 3:123,245,481...123,376,455
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G |
Dnah11 |
dynein, axonemal, heavy chain 11 |
increases expression |
ISO |
nickel sulfate results in increased expression of DNAH11 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 6:145,784,893...146,099,212
Ensembl chr 6:145,785,275...146,099,053
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G |
Dnah9 |
dynein, axonemal, heavy chain 9 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DNAH9 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr10:52,351,226...52,711,289
Ensembl chr10:52,351,192...52,710,862
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G |
Dnaja4 |
DnaJ heat shock protein family (Hsp40) member A4 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DNAJA4 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 8:59,278,262...59,294,003
Ensembl chr 8:59,278,262...59,294,003
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G |
Dnajb6 |
DnaJ heat shock protein family (Hsp40) member B6 |
increases expression |
ISO |
nickel sulfate results in increased expression of DNAJB6 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 4:2,711,329...2,774,969
Ensembl chr 4:2,711,385...2,774,890
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G |
Dnajc1 |
DnaJ heat shock protein family (Hsp40) member C1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DNAJC1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:84,986,994...85,141,464
Ensembl chr17:84,986,991...85,141,210
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|
G |
Dnali1 |
dynein, axonemal, light intermediate chain 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DNALI1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 5:143,053,365...143,062,203
Ensembl chr 5:143,053,367...143,062,226
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|
G |
Dnm3 |
dynamin 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DNM3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr13:79,906,711...80,379,967
Ensembl chr13:79,910,382...80,379,929
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G |
Dock10 |
dedicator of cytokinesis 10 |
increases expression |
ISO |
nickel sulfate results in increased expression of DOCK10 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 9:86,424,638...86,571,854 NCBI chr 9:86,312,470...86,423,054
Ensembl chr 9:86,312,501...86,571,870
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G |
Dock11 |
dedicator of cytokinesis 11 |
increases expression |
ISO |
nickel sulfate results in increased expression of DOCK11 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr X:122,507,169...122,690,463
Ensembl chr X:122,507,374...122,690,465
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|
G |
Dpp4 |
dipeptidylpeptidase 4 |
decreases expression increases expression |
ISO |
nickel sulfate results in decreased expression of DPP4 mRNA nickel sulfate results in increased expression of DPP4 mRNA |
CTD |
PMID:16780908 PMID:22714537 |
|
NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
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G |
Dpp7 |
dipeptidylpeptidase 7 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DPP7 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:2,569,135...2,573,387
Ensembl chr 3:2,569,135...2,573,387
|
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G |
Dpy19l3 |
dpy-19 like C-mannosyltransferase 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DPY19L3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:92,002,927...92,069,855
Ensembl chr 1:92,002,927...92,069,160
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G |
Dpyd |
dihydropyrimidine dehydrogenase |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DPYD mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 2:221,823,692...222,694,627
Ensembl chr 2:221,823,687...222,694,627
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G |
Dram1 |
DNA-damage regulated autophagy modulator 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of DRAM1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 7:28,898,647...28,932,641
Ensembl chr 7:28,898,649...28,932,641
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G |
Dse |
dermatan sulfate epimerase |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DSE mRNA |
CTD |
PMID:17374397 |
|
NCBI chr20:27,703,738...27,784,982
Ensembl chr20:27,703,732...27,782,586
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G |
Dsel |
dermatan sulfate epimerase-like |
increases expression |
ISO |
nickel sulfate results in increased expression of DSEL mRNA |
CTD |
PMID:22714537 |
|
NCBI chr13:1,942,384...1,948,563
Ensembl chr13:1,942,499...1,946,508
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G |
Dsg2 |
desmoglein 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of DSG2 mRNA |
CTD |
PMID:16780908 PMID:22714537 |
|
NCBI chr18:15,579,322...15,637,720
Ensembl chr18:15,579,315...15,637,715
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G |
Dstn |
destrin, actin depolymerizing factor |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DSTN mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:138,024,508...138,051,304
Ensembl chr 3:138,024,508...138,051,298
|
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G |
Dtd1 |
D-aminoacyl-tRNA deacylase 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DTD1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:138,770,573...138,931,544
Ensembl chr 3:138,770,574...138,931,549
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G |
Dtx3 |
deltex E3 ubiquitin ligase 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DTX3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 7:70,476,737...70,482,852
Ensembl chr 7:70,476,729...70,481,796
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G |
Dusp1 |
dual specificity phosphatase 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of DUSP1 mRNA |
CTD |
PMID:16314067 |
|
NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
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G |
Dusp10 |
dual specificity phosphatase 10 |
increases expression |
ISO |
nickel sulfate results in increased expression of DUSP10 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr13:104,284,660...104,321,455
Ensembl chr13:104,284,660...104,321,455
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|
G |
Dusp22 |
dual specificity phosphatase 22 |
increases expression |
ISO |
nickel sulfate results in increased expression of DUSP22 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:34,986,589...35,037,297
Ensembl chr17:34,986,591...35,037,076
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G |
Dusp23 |
dual specificity phosphatase 23 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DUSP23 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr13:91,018,670...91,019,862
Ensembl chr13:91,018,510...91,020,112
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G |
Dusp4 |
dual specificity phosphatase 4 |
increases expression |
ISO |
nickel sulfate results in increased expression of DUSP4 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr16:61,080,767...61,090,973
Ensembl chr16:61,078,175...61,091,169
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G |
Dusp5 |
dual specificity phosphatase 5 |
increases expression |
ISO |
nickel sulfate results in increased expression of DUSP5 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
|
|
G |
Dync2h1 |
dynein cytoplasmic 2 heavy chain 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DYNC2H1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 8:5,217,054...5,436,969
Ensembl chr 8:5,217,217...5,429,581
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G |
Dysf |
dysferlin |
decreases expression |
ISO |
nickel sulfate results in decreased expression of DYSF mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:115,700,942...115,901,873
Ensembl chr 4:115,712,850...115,901,873
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G |
Ebi3 |
Epstein-Barr virus induced 3 |
increases expression multiple interactions |
ISO |
nickel sulfate results in increased expression of EBI3 mRNA BAY 11-7085 inhibits the reaction [nickel sulfate results in increased expression of EBI3 mRNA]; TLR4 protein affects the reaction [nickel sulfate results in increased expression of EBI3 mRNA] |
CTD |
PMID:16780908 PMID:30421605 |
|
NCBI chr 9:11,110,874...11,114,843
Ensembl chr 9:11,110,874...11,114,843
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G |
Ece1 |
endothelin converting enzyme 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of ECE1 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671
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G |
Echdc3 |
enoyl CoA hydratase domain containing 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ECHDC3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:76,002,304...76,022,813
Ensembl chr17:76,002,275...76,022,813
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G |
Ecm1 |
extracellular matrix protein 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of ECM1 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr 2:197,855,468...197,860,973
Ensembl chr 2:197,855,460...197,860,699
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G |
Edaradd |
EDAR-associated death domain |
increases expression |
ISO |
nickel sulfate results in increased expression of EDARADD mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:90,802,280...90,843,476
Ensembl chr17:90,802,393...90,843,485
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G |
Edem3 |
ER degradation enhancing alpha-mannosidase like protein 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of EDEM3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr13:69,135,095...69,197,708
Ensembl chr13:69,135,128...69,199,511
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G |
Edil3 |
EGF like repeats and discoidin domains 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of EDIL3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:17,616,116...18,128,514
Ensembl chr 2:17,616,401...18,128,512
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|
G |
Edn1 |
endothelin 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of EDN1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
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|
G |
Efemp2 |
EGF containing fibulin extracellular matrix protein 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of EFEMP2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:220,853,695...220,861,420
Ensembl chr 1:220,854,403...220,861,420
|
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G |
Efhc1 |
EF-hand domain containing 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of EFHC1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 9:27,068,505...27,107,713
Ensembl chr 9:27,068,443...27,107,709
|
|
G |
Efna1 |
ephrin A1 |
multiple interactions increases expression |
ISO |
[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of EFNA1 mRNA nickel sulfate results in increased expression of EFNA1 mRNA |
CTD |
PMID:18651567 PMID:18832182 |
|
NCBI chr 2:188,588,808...188,596,156
Ensembl chr 2:188,588,796...188,596,222
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|
G |
Efna3 |
ephrin A3 |
increases expression multiple interactions |
ISO |
nickel sulfate results in increased expression of EFNA3 mRNA [macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of EFNA3 mRNA |
CTD |
PMID:18832182 |
|
NCBI chr 2:188,636,304...188,645,302
Ensembl chr 2:188,637,852...188,645,196
|
|
G |
Efna5 |
ephrin A5 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of EFNA5 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 9:110,054,002...110,329,878
Ensembl chr 9:110,057,155...110,225,486
|
|
G |
Egfr |
epidermal growth factor receptor |
multiple interactions |
ISO |
[TGFA protein binds to and affects the activity of EGFR protein] which results in decreased susceptibility to nickel sulfate |
CTD |
PMID:19131640 |
|
NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
|
|
G |
Egr1 |
early growth response 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of EGR1 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
|
|
G |
Ehhadh |
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase |
increases expression |
ISO |
nickel sulfate results in increased expression of EHHADH mRNA |
CTD |
PMID:17374397 PMID:22714537 |
|
NCBI chr11:82,945,104...82,978,364
Ensembl chr11:82,945,104...82,978,364
|
|
G |
Ehmt2 |
euchromatic histone lysine methyltransferase 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of EHMT2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr20:4,576,033...4,592,980
Ensembl chr20:4,576,057...4,592,980
|
|
G |
Ei24 |
EI24, autophagy associated transmembrane protein |
decreases expression |
ISO |
nickel sulfate results in decreased expression of EI24 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr 8:39,254,883...39,271,238
Ensembl chr 8:39,254,889...39,266,959
|
|
G |
Eif4g1 |
eukaryotic translation initiation factor 4 gamma, 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of EIF4G1 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr11:83,907,659...83,927,683
Ensembl chr11:83,908,109...83,926,524
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|
G |
Eln |
elastin |
increases expression |
ISO |
nickel sulfate results in increased expression of ELN mRNA |
CTD |
PMID:16100012 |
|
NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863
|
|
G |
Elovl2 |
ELOVL fatty acid elongase 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of ELOVL2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:21,382,461...21,422,413
Ensembl chr17:21,382,455...21,422,407
|
|
G |
Elovl3 |
ELOVL fatty acid elongase 3 |
multiple interactions |
ISO |
[nickel sulfate co-treated with Particulate Matter] results in decreased expression of ELOVL3 mRNA |
CTD |
PMID:23126276 |
|
NCBI chr 1:265,883,353...265,887,181
Ensembl chr 1:265,883,355...265,887,226
|
|
G |
Elovl7 |
ELOVL fatty acid elongase 7 |
increases expression |
ISO |
nickel sulfate results in increased expression of ELOVL7 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:40,373,211...40,386,643
Ensembl chr 2:40,373,211...40,386,669
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G |
Emb |
embigin |
decreases expression |
ISO |
nickel sulfate results in decreased expression of EMB mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 2:49,682,763...49,733,475
Ensembl chr 2:49,682,754...49,732,253
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G |
Emc8 |
ER membrane protein complex subunit 8 |
increases expression |
ISO |
nickel sulfate results in increased expression of EMC8 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr19:54,235,949...54,245,810
Ensembl chr19:54,235,936...54,245,855
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G |
Eml1 |
EMAP like 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of EML1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 6:132,367,342...132,450,488
Ensembl chr 6:132,383,337...132,450,393
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|
G |
Emp1 |
epithelial membrane protein 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of EMP1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:169,161,076...169,181,967
Ensembl chr 4:169,147,243...169,181,966
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G |
Enc1 |
ectodermal-neural cortex 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ENC1 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 2:28,049,217...28,061,023
Ensembl chr 2:28,049,217...28,061,029
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G |
Endod1 |
endonuclease domain containing 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ENDOD1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 8:12,898,430...12,928,156
|
|
G |
Eno1 |
enolase 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of ENO1 mRNA |
CTD |
PMID:16100012 |
|
NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
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G |
Eno2 |
enolase 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of ENO2 mRNA |
CTD |
PMID:17382205 |
|
NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047 Ensembl chr 9:157,285,179...157,294,047
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G |
Eno3 |
enolase 3 |
affects expression |
ISO |
nickel sulfate affects the expression of ENO3 mRNA |
CTD |
PMID:12718980 |
|
NCBI chr10:57,278,271...57,283,661
Ensembl chr10:57,278,307...57,283,653
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G |
Enpp1 |
ectonucleotide pyrophosphatase/phosphodiesterase 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of ENPP1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:21,748,201...21,813,205
Ensembl chr 1:21,748,261...21,813,371
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|
G |
Enpp4 |
ectonucleotide pyrophosphatase/phosphodiesterase 4 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ENPP4 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 9:19,446,807...19,457,946
Ensembl chr 9:19,448,269...19,457,946
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G |
Entpd1 |
ectonucleoside triphosphate diphosphohydrolase 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of ENTPD1 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 1:259,692,020...259,818,922
Ensembl chr 1:259,739,955...259,819,494
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G |
Entpd6 |
ectonucleoside triphosphate diphosphohydrolase 6 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ENTPD6 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:146,546,424...146,568,828
Ensembl chr 3:146,546,387...146,568,825
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G |
Epas1 |
endothelial PAS domain protein 1 |
multiple interactions increases expression increases stability |
ISO |
[HIF1A mRNA co-treated with EPAS1 mRNA] affects the reaction [nickel sulfate results in decreased expression of USP28 protein]; [HIF1A mRNA co-treated with EPAS1 mRNA] affects the reaction [nickel sulfate results in increased degradation of MYC protein]; Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of EPAS1 protein] nickel sulfate results in increased expression of EPAS1 mRNA; nickel sulfate results in increased expression of EPAS1 protein nickel sulfate results in increased stability of EPAS1 protein |
CTD |
PMID:16288478 PMID:20046830 PMID:22714537 |
|
NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
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|
G |
Epcam |
epithelial cell adhesion molecule |
decreases expression |
ISO |
nickel sulfate results in decreased expression of EPCAM mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 6:11,282,194...11,308,870
Ensembl chr 6:11,281,964...11,298,216
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G |
Epdr1 |
ependymin related 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of EPDR1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:47,397,558...47,422,183
Ensembl chr17:47,397,558...47,422,182
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|
G |
Epha4 |
Eph receptor A4 |
increases expression |
ISO |
nickel sulfate results in increased expression of EPHA4 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 9:83,111,222...83,253,486
Ensembl chr 9:83,111,222...83,253,458
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G |
Ephb6 |
Eph receptor B6 |
increases expression |
ISO |
nickel sulfate results in increased expression of EPHB6 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr 4:70,903,253...70,918,514
Ensembl chr 4:70,903,253...70,918,514
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|
G |
Epm2aip1 |
EPM2A interacting protein 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of EPM2AIP1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 8:119,524,039...119,531,387
Ensembl chr 8:119,524,039...119,531,387
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|
G |
Erbb3 |
erb-b2 receptor tyrosine kinase 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ERBB3 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350
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G |
Esd |
esterase D |
increases expression |
ISO |
nickel sulfate results in increased expression of ESD mRNA |
CTD |
PMID:16100012 |
|
NCBI chr15:56,756,848...56,776,348
Ensembl chr15:56,756,661...56,776,348
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|
G |
Esf1 |
ESF1 nucleolar pre-rRNA processing protein homolog |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ESF1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:133,178,591...133,232,358
Ensembl chr 3:133,178,561...133,232,322
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G |
Etl4 |
enhancer trap locus 4 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of KIAA1217 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:87,173,265...87,681,268
Ensembl chr17:87,274,944...87,681,317
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|
G |
Ets1 |
ETS proto-oncogene 1, transcription factor |
multiple interactions |
EXP |
[nickel sulfate results in increased abundance of Nickel] which results in increased expression of ETS1 mRNA |
CTD |
PMID:31734292 |
|
NCBI chr 8:33,756,634...33,879,625
Ensembl chr 8:33,816,386...33,879,625
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|
G |
Ets2 |
ETS proto-oncogene 2, transcription factor |
increases expression |
ISO |
nickel sulfate results in increased expression of ETS2 mRNA |
CTD |
PMID:16780908 PMID:18651567 |
|
NCBI chr11:36,075,709...36,092,495
Ensembl chr11:36,075,709...36,092,495
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|
G |
Etv2 |
ETS variant transcription factor 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of ETV2 mRNA |
CTD |
PMID:17382205 |
|
NCBI chr 1:89,091,239...89,094,570
Ensembl chr 1:89,091,239...89,094,530
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|
G |
Etv6 |
ETS variant transcription factor 6 |
increases expression |
ISO |
nickel sulfate results in increased expression of ETV6 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:167,754,684...167,992,370
Ensembl chr 4:167,754,525...167,992,168
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|
G |
Eva1c |
eva-1 homolog C |
increases expression |
ISO |
nickel sulfate results in increased expression of EVA1C mRNA |
CTD |
PMID:22714537 |
|
NCBI chr11:31,001,697...31,075,784
Ensembl chr11:31,002,451...31,075,809
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|
G |
Evi2b |
ecotropic viral integration site 2B |
increases expression |
ISO |
nickel sulfate results in increased expression of EVI2B mRNA |
CTD |
PMID:22714537 |
|
NCBI chr10:66,856,980...66,858,598
Ensembl chr10:66,856,980...66,858,598
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|
G |
Exoc2 |
exocyst complex component 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of EXOC2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:34,665,810...34,842,266
Ensembl chr17:34,665,872...34,842,266 Ensembl chr17:34,665,872...34,842,266
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|
G |
Exoc6 |
exocyst complex component 6 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of EXOC6 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 1:256,211,879...256,369,318
Ensembl chr 1:256,226,179...256,368,813
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|
G |
Exosc8 |
exosome component 8 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of EXOSC8 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:143,925,643...143,932,240
Ensembl chr 2:143,925,546...143,931,940
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|
G |
Exph5 |
exophilin 5 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of EXPH5 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 8:57,885,932...57,962,574
Ensembl chr 8:57,886,168...57,962,708
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|
G |
Eya1 |
EYA transcriptional coactivator and phosphatase 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of EYA1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 5:4,275,728...4,495,525
Ensembl chr 5:4,373,626...4,513,142
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|
G |
Eya2 |
EYA transcriptional coactivator and phosphatase 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of EYA2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:162,285,275...162,470,642
Ensembl chr 3:162,346,490...162,470,065
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|
G |
F13a1 |
coagulation factor XIII A1 chain |
decreases expression |
ISO |
nickel sulfate results in decreased expression of F13A1 mRNA |
CTD |
PMID:16780908 PMID:17374397 |
|
NCBI chr17:28,504,650...28,680,015
Ensembl chr17:28,504,623...28,680,362
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|
G |
F2rl2 |
coagulation factor II (thrombin) receptor-like 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of F2RL2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:26,240,385...26,245,533
Ensembl chr 2:26,240,385...26,245,533
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G |
F3 |
coagulation factor III, tissue factor |
increases expression decreases expression |
ISO |
nickel sulfate results in increased expression of F3 mRNA nickel sulfate results in decreased expression of F3 mRNA |
CTD |
PMID:16100012 PMID:22714537 |
|
NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
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G |
Fabp3 |
fatty acid binding protein 3 |
increases expression decreases expression |
ISO |
nickel sulfate results in increased expression of FABP3 mRNA nickel sulfate results in decreased expression of FABP3 mRNA |
CTD |
PMID:17382205 PMID:22714537 |
|
NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565
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G |
Fabp5 |
fatty acid binding protein 5 |
increases expression decreases expression |
ISO |
nickel sulfate results in increased expression of FABP5 mRNA nickel sulfate results in decreased expression of FABP5 mRNA |
CTD |
PMID:16780908 PMID:18651567 |
|
NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378
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G |
Fam117b |
family with sequence similarity 117, member B |
increases expression |
ISO |
nickel sulfate results in increased expression of FAM117B mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 9:66,716,969...66,784,487
Ensembl chr 9:66,716,969...66,784,487
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G |
FAM120C |
family with sequence similarity 120C |
increases expression |
ISO |
nickel sulfate results in increased expression of FAM120C mRNA |
CTD |
PMID:22714537 |
|
NCBI chr X:20,481,800...21,016,980
Ensembl chr X:20,484,517...21,015,836
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G |
Fam162a |
family with sequence similarity 162, member A |
increases expression decreases expression |
ISO |
nickel sulfate results in increased expression of FAM162A mRNA nickel sulfate results in decreased expression of FAM162A mRNA |
CTD |
PMID:17382205 PMID:22714537 |
|
NCBI chr11:67,618,683...67,646,253
Ensembl chr11:67,618,625...67,646,253
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G |
Fam171b |
family with sequence similarity 171, member B |
increases expression |
ISO |
nickel sulfate results in increased expression of FAM171B mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:71,210,048...71,265,419
Ensembl chr 3:71,210,301...71,262,615
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G |
Fam221a |
family with sequence similarity 221, member A |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FAM221A mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:79,021,840...79,043,806
Ensembl chr 4:79,021,872...79,043,844
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G |
Fam3c |
FAM3 metabolism regulating signaling molecule C |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FAM3C mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:49,388,962...49,439,892
Ensembl chr 4:49,387,989...49,439,867
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G |
Fam43a |
family with sequence similarity 43, member A |
increases expression |
ISO |
nickel sulfate results in increased expression of FAM43A mRNA |
CTD |
PMID:22714537 |
|
NCBI chr11:73,676,601...73,679,003
Ensembl chr11:73,676,601...73,678,984
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G |
Fam81a |
family with sequence similarity 81, member A |
increases expression |
ISO |
nickel sulfate results in increased expression of FAM81A mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 8:76,521,662...76,579,387
Ensembl chr 8:76,521,657...76,579,387
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G |
Fanca |
FA complementation group A |
increases expression |
ISO |
nickel sulfate results in increased expression of FANCA mRNA |
CTD |
PMID:22714537 |
|
NCBI chr19:56,067,548...56,126,075
Ensembl chr19:56,067,548...56,126,063
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G |
Farp1 |
FERM, ARH/RhoGEF and pleckstrin domain protein 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of FARP1 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr15:106,375,298...106,625,837
Ensembl chr15:106,434,177...106,625,837
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|
G |
Fars2 |
phenylalanyl-tRNA synthetase 2, mitochondrial |
increases expression |
ISO |
nickel sulfate results in increased expression of FARS2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:29,006,981...29,438,906
Ensembl chr17:29,006,988...29,438,668
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G |
Fasn |
fatty acid synthase |
increases expression decreases expression |
ISO |
nickel sulfate results in increased expression of FASN mRNA nickel sulfate results in decreased expression of FASN mRNA |
CTD |
PMID:16100012 PMID:16780908 |
|
NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
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G |
Faxc |
failed axon connections homolog, metaxin like GST domain containing |
increases expression |
ISO |
nickel sulfate results in increased expression of FAXC mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 5:36,076,565...36,135,884
Ensembl chr 5:36,076,565...36,135,884
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G |
Fbln2 |
fibulin 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FBLN2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:122,835,237...122,895,127
Ensembl chr 4:122,835,436...122,895,121
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G |
Fbn1 |
fibrillin 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FBN1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:117,569,708...117,766,160
Ensembl chr 3:117,569,697...117,766,120
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G |
Fbn2 |
fibrillin 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FBN2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr18:53,068,495...53,272,254
Ensembl chr18:53,068,495...53,181,503
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|
G |
Fbxo32 |
F-box protein 32 |
increases expression |
ISO |
nickel sulfate results in increased expression of FBXO32 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 7:98,065,664...98,098,071
Ensembl chr 7:98,063,735...98,098,268
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|
G |
Fbxo4 |
F-box protein 4 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FBXO4 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:53,797,954...53,811,134
Ensembl chr 2:53,797,954...53,811,134
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G |
Fbxo9 |
f-box protein 9 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FBXO9 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr 8:85,388,331...85,413,896
Ensembl chr 8:85,388,333...85,413,484
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|
G |
Fbxw7 |
F-box and WD repeat domain containing 7 |
multiple interactions |
ISO |
FBXW7 mRNA affects the reaction [nickel sulfate results in increased degradation of MYC protein]; FBXW7 protein affects the reaction [nickel sulfate results in increased degradation of MYC protein] |
CTD |
PMID:20046830 |
|
NCBI chr 2:184,230,191...184,309,805
Ensembl chr 2:184,231,260...184,309,664
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|
G |
Fcgr2b |
Fc fragment of IgG receptor IIb |
increases expression |
ISO |
nickel sulfate results in increased expression of FCGR2B mRNA |
CTD |
PMID:17374397 |
|
NCBI chr13:89,329,298...89,343,916
Ensembl chr13:89,327,794...89,433,815
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G |
Fech |
ferrochelatase |
increases expression |
ISO |
nickel sulfate results in increased expression of FECH mRNA |
CTD |
PMID:20566472 |
|
NCBI chr18:59,941,992...59,975,192
Ensembl chr18:59,941,992...59,975,192
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|
G |
Fetub |
fetuin B |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FETUB mRNA |
CTD |
PMID:18651567 |
|
NCBI chr11:81,648,890...81,660,472
Ensembl chr11:81,648,885...81,660,395
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|
G |
Fez2 |
fasciculation and elongation protein zeta 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of FEZ2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 6:963,903...1,003,955
Ensembl chr 6:963,907...1,004,001
|
|
G |
Fgf1 |
fibroblast growth factor 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FGF1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
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|
G |
Fgf2 |
fibroblast growth factor 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of FGF2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
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|
G |
Fgf5 |
fibroblast growth factor 5 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FGF5 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr14:12,974,921...12,996,046
Ensembl chr14:12,974,921...12,995,584
|
|
G |
Fgfr2 |
fibroblast growth factor receptor 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of FGFR2 protein |
CTD |
PMID:12930308 |
|
NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
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|
G |
Fgl2 |
fibrinogen-like 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FGL2 mRNA |
CTD |
PMID:16780908 PMID:17374397 |
|
NCBI chr 4:10,323,598...10,329,241
Ensembl chr 4:10,323,607...10,329,241
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|
G |
Filip1l |
filamin A interacting protein 1-like |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FILIP1L mRNA |
CTD |
PMID:22714537 |
|
NCBI chr11:45,039,488...45,275,141
Ensembl chr11:45,039,461...45,124,423
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|
G |
Fkbp1a |
FKBP prolyl isomerase 1A |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FKBP1A mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:147,042,944...147,062,725
Ensembl chr 3:147,042,944...147,062,724
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|
G |
Fkbp1b |
FKBP prolyl isomerase 1B |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FKBP1B mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 6:29,975,863...29,987,252
Ensembl chr 6:29,977,797...29,987,451
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G |
Flg |
filaggrin |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FLG mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:193,565,401...193,574,297
|
|
G |
Fli1 |
Fli-1 proto-oncogene, ETS transcription factor |
increases expression |
ISO |
nickel sulfate results in increased expression of FLI1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 8:33,541,932...33,661,111
Ensembl chr 8:33,543,258...33,661,049
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|
G |
Flna |
filamin A |
increases expression |
ISO |
nickel sulfate results in increased expression of FLNA mRNA |
CTD |
PMID:18651567 |
|
NCBI chr X:156,460,785...156,487,245
Ensembl chr X:156,463,953...156,487,245
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|
G |
Flnc |
filamin C |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FLNC mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:56,710,934...56,738,779
Ensembl chr 4:56,711,049...56,738,791
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|
G |
Flot1 |
flotillin 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of FLOT1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr20:3,427,890...3,438,418
Ensembl chr20:3,427,880...3,438,396
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|
G |
Flt1 |
Fms related receptor tyrosine kinase 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of FLT1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
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|
G |
Flt3lg |
Fms related receptor tyrosine kinase 3 ligand |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FLT3L mRNA |
CTD |
PMID:16100012 |
|
NCBI chr 1:101,126,006...101,131,413
Ensembl chr 1:101,124,479...101,131,413
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|
G |
Fmr1 |
FMRP translational regulator 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FMR1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr X:154,684,924...154,722,369
Ensembl chr X:154,684,935...154,722,314
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|
G |
Fn1 |
fibronectin 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of FN1 mRNA; nickel sulfate results in increased expression of FN1 protein |
CTD |
PMID:22648416 |
|
NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
|
|
G |
Fndc3a |
fibronectin type III domain containing 3a |
increases expression |
EXP |
nickel sulfate results in increased expression of FNDC3A mRNA |
CTD |
PMID:11114790 |
|
NCBI chr15:54,378,865...54,582,954
Ensembl chr15:54,381,044...54,528,480
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|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
nickel sulfate results in increased expression of FOS mRNA |
CTD |
PMID:16780908 PMID:19131640 |
|
NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
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|
G |
Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
decreases expression increases expression |
ISO |
nickel sulfate results in decreased expression of FOSL2 mRNA nickel sulfate results in increased expression of FOSL2 mRNA |
CTD |
PMID:16780908 PMID:17374397 |
|
NCBI chr 6:25,598,936...25,616,995
Ensembl chr 6:25,598,936...25,616,995
|
|
G |
Foxc2 |
forkhead box C2 |
increases expression |
ISO |
nickel sulfate results in increased expression of FOXC2 mRNA |
CTD |
PMID:16100012 |
|
NCBI chr19:53,044,379...53,047,081
Ensembl chr19:53,044,379...53,047,081
|
|
G |
Foxf2 |
forkhead box F2 |
increases expression |
ISO |
nickel sulfate results in increased expression of FOXF2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:34,150,417...34,156,450
|
|
G |
Fpr3 |
formyl peptide receptor 3 |
increases expression |
ISO |
nickel sulfate results in increased expression of FPR3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:116,152,526...116,161,873
Ensembl chr 1:116,152,667...116,153,722
|
|
G |
Frmd3 |
FERM domain containing 3 |
increases expression |
ISO |
nickel sulfate results in increased expression of FRMD3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 5:90,040,495...90,282,327
Ensembl chr 5:90,040,495...90,282,327
|
|
G |
Frmd4a |
FERM domain containing 4A |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FRMD4A mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:77,642,302...77,918,210
|
|
G |
Frmd5 |
FERM domain containing 5 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FRMD5 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:113,480,780...113,755,286
Ensembl chr 3:113,483,269...113,525,864
|
|
G |
Fry |
FRY microtubule binding protein |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FRY mRNA |
CTD |
PMID:22714537 |
|
NCBI chr12:5,573,729...5,822,874
Ensembl chr12:5,573,729...5,822,874
|
|
G |
Fst |
follistatin |
increases expression |
ISO |
nickel sulfate results in increased expression of FST mRNA |
CTD |
PMID:16100012 |
|
NCBI chr 2:46,537,589...46,544,813
Ensembl chr 2:46,538,700...46,544,457
|
|
G |
Fstl3 |
follistatin like 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FSTL3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 7:12,806,031...12,810,556
Ensembl chr 7:12,804,919...12,810,570
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|
G |
Fth1 |
ferritin heavy chain 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of FTH1 mRNA |
CTD |
PMID:16314067 |
|
NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
|
|
G |
Ftl1 |
ferritin light chain 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of FTL mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
|
|
G |
Ftmt |
ferritin mitochondrial |
increases expression |
EXP |
nickel sulfate results in increased expression of FTMT protein |
CTD |
PMID:19679144 |
|
NCBI chr18:47,294,292...47,295,541
Ensembl chr18:47,294,292...47,295,541
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|
G |
Fuca1 |
alpha-L-fucosidase 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FUCA1 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 5:154,269,296...154,286,545
Ensembl chr 5:154,269,118...154,286,544
|
|
G |
Fundc2 |
FUN14 domain containing 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FUNDC2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr18:401,878...407,954
Ensembl chr18:402,295...407,954
|
|
G |
Fus |
FUS RNA binding protein |
increases expression |
ISO |
nickel sulfate results in increased expression of FUS mRNA |
CTD |
PMID:18651567 |
|
NCBI chr 1:199,412,805...199,426,705
Ensembl chr 1:199,412,834...199,426,702
|
|
G |
Fyn |
FYN proto-oncogene, Src family tyrosine kinase |
increases expression |
ISO |
nickel sulfate results in increased expression of FYN mRNA |
CTD |
PMID:16780908 |
|
NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
|
|
G |
Fzd2 |
frizzled class receptor 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FZD2 mRNA |
CTD |
PMID:16100012 PMID:16166746 |
|
NCBI chr10:90,550,147...90,552,057
Ensembl chr10:90,550,147...90,552,057
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|
G |
Fzd3 |
frizzled class receptor 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of FZD3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr15:48,601,259...48,670,257
Ensembl chr15:48,601,266...48,670,257
|
|
G |
Fzd6 |
frizzled class receptor 6 |
increases expression |
ISO |
nickel sulfate results in increased expression of FZD6 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 7:77,898,329...77,931,034
Ensembl chr 7:77,899,322...77,931,029
|
|
G |
G4 |
G4 protein |
increases expression |
ISO |
nickel sulfate results in increased expression of C6ORF47 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr20:5,118,006...5,120,332
Ensembl chr20:5,118,002...5,120,332
|
|
G |
G6pd |
glucose-6-phosphate dehydrogenase |
increases expression decreases activity multiple interactions |
ISO EXP |
nickel sulfate results in increased expression of G6PD mRNA nickel sulfate results in decreased activity of G6PD protein naringin inhibits the reaction [nickel sulfate results in decreased activity of G6PD protein] |
CTD |
PMID:20566472 PMID:20950607 |
|
NCBI chr X:156,274,800...156,293,935
Ensembl chr X:156,274,800...156,293,926
|
|
G |
Gabarapl1 |
GABA type A receptor associated protein like 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of GABARAPL1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:163,293,724...163,302,866
Ensembl chr 4:163,293,724...163,302,858
|
|
G |
Gad1 |
glutamate decarboxylase 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of GAD1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
|
|
G |
Gal |
galanin and GMAP prepropeptide |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GAL mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
|
|
G |
Gal3st4 |
galactose-3-O-sulfotransferase 4 |
increases expression |
ISO |
nickel sulfate results in increased expression of GAL3ST4 mRNA |
CTD |
PMID:17382205 |
|
NCBI chr12:19,583,110...19,592,444
Ensembl chr12:19,583,110...19,592,000
|
|
G |
Galc |
galactosylceramidase |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GALC mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 6:122,177,195...122,239,411
Ensembl chr 6:122,178,602...122,239,614
|
|
G |
Galns |
galactosamine (N-acetyl)-6-sulfatase |
increases expression |
ISO |
nickel sulfate results in increased expression of GALNS mRNA |
CTD |
PMID:22714537 |
|
NCBI chr19:55,391,004...55,423,328
Ensembl chr19:55,389,462...55,423,150
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|
G |
Gan |
gigaxonin |
increases expression |
ISO |
nickel sulfate results in increased expression of GAN mRNA |
CTD |
PMID:22714537 |
|
NCBI chr19:49,692,790...49,746,178
Ensembl chr19:49,695,579...49,741,965
|
|
G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
affects expression |
ISO |
nickel sulfate affects the expression of GAPDH mRNA |
CTD |
PMID:12718980 |
|
NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
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|
G |
Gas6 |
growth arrest specific 6 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GAS6 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
|
|
G |
Gas8 |
growth arrest specific 8 |
increases expression |
ISO |
nickel sulfate results in increased expression of GAS8 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr19:56,316,367...56,335,873
Ensembl chr19:56,316,268...56,335,870
|
|
G |
Gatm |
glycine amidinotransferase |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GATM mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 3:114,711,570...114,728,155
Ensembl chr 3:114,711,562...114,728,410
|
|
G |
Gbp1 |
guanylate binding protein 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of GBP1 mRNA |
CTD |
PMID:16166746 |
|
NCBI chr 2:248,343,334...248,423,402
Ensembl chr 2:248,398,917...248,409,570
|
|
G |
Gbp4 |
guanylate binding protein 4 |
increases expression |
ISO |
nickel sulfate results in increased expression of GBP4 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:248,249,232...248,263,104
Ensembl chr 2:248,249,468...248,263,168
|
|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression |
ISO |
nickel sulfate results in increased expression of GCLC mRNA |
CTD |
PMID:16100012 PMID:20491607 PMID:20566472 |
|
NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
|
|
G |
Gclm |
glutamate cysteine ligase, modifier subunit |
increases expression |
ISO |
nickel sulfate results in increased expression of GCLM mRNA |
CTD |
PMID:16314067 PMID:20566472 |
|
NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
|
|
G |
Gcnt2 |
glucosaminyl (N-acetyl) transferase 2 (I blood group) |
increases expression |
ISO |
nickel sulfate results in increased expression of GCNT2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:21,634,546...21,677,477
Ensembl chr17:21,634,551...21,739,408
|
|
G |
Gcnt4 |
glucosaminyl (N-acetyl) transferase 4 |
increases expression |
ISO |
nickel sulfate results in increased expression of GCNT4 mRNA |
CTD |
PMID:22714537 |
|
Ensembl chr 2:27,713,880...27,780,119
|
|
G |
Gcsh |
glycine cleavage system protein H |
increases expression |
ISO |
nickel sulfate results in increased expression of GCSH mRNA |
CTD |
PMID:22714537 |
|
NCBI chr19:49,522,054...49,532,811
Ensembl chr19:49,522,054...49,532,811
|
|
G |
Gdf15 |
growth differentiation factor 15 |
increases expression |
ISO |
nickel sulfate results in increased expression of GDF15 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
|
|
G |
Gdnf |
glial cell derived neurotrophic factor |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GDNF mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
|
|
G |
Gfpt2 |
glutamine-fructose-6-phosphate transaminase 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of GFPT2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr10:35,279,237...35,325,506
Ensembl chr10:35,279,236...35,325,508
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|
G |
Gfra2 |
GDNF family receptor alpha 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GFRA2 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr15:52,557,004...52,648,984
Ensembl chr15:52,557,607...52,648,972
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|
G |
Gfus |
GDP-L-fucose synthase |
increases expression |
ISO |
nickel sulfate results in increased expression of GFUS mRNA |
CTD |
PMID:18651567 |
|
NCBI chr 7:116,958,427...116,963,281
Ensembl chr 7:116,958,392...116,963,295
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|
G |
Ggt1 |
gamma-glutamyltransferase 1 |
increases activity multiple interactions |
EXP |
nickel sulfate results in increased activity of GGT1 protein troxerutin inhibits the reaction [nickel sulfate results in increased activity of GGT1 protein] |
CTD |
PMID:24112957 |
|
NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
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|
G |
Gins1 |
GINS complex subunit 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GINS1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:146,695,366...146,716,787
Ensembl chr 3:146,695,344...146,716,816
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|
G |
Gins2 |
GINS complex subunit 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of GINS2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr19:54,151,048...54,163,701
Ensembl chr19:54,151,048...54,163,608
|
|
G |
Gja1 |
gap junction protein, alpha 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of GJA1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
|
|
G |
Glcci1 |
glucocorticoid induced 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GLCCI1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:34,282,625...34,612,709
Ensembl chr 4:34,282,625...34,614,438
|
|
G |
Glipr1 |
GLI pathogenesis-related 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GLIPR1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 7:54,767,828...54,778,823
Ensembl chr 7:54,767,827...54,778,848
|
|
G |
Glipr2 |
GLI pathogenesis-related 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GLIPR2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 5:59,415,415...59,446,732
Ensembl chr 5:59,416,076...59,446,647
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|
G |
Glis3 |
GLIS family zinc finger 3 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GLIS3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:246,380,816...246,564,385
Ensembl chr 1:246,380,889...246,785,360
|
|
G |
Glp2r |
glucagon-like peptide 2 receptor |
increases expression |
ISO |
nickel sulfate results in increased expression of GLP2R mRNA |
CTD |
PMID:22714537 |
|
NCBI chr10:54,260,290...54,323,839
Ensembl chr10:54,260,290...54,323,439
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|
G |
Glrb |
glycine receptor, beta |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GLRB mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:179,768,040...179,842,612
Ensembl chr 2:179,769,009...179,842,547
|
|
G |
Glul |
glutamate-ammonia ligase |
increases expression |
ISO |
nickel sulfate results in increased expression of GLUL mRNA |
CTD |
PMID:22714537 |
|
NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
|
|
G |
Gm2a |
GM2 ganglioside activator |
decreases expression increases expression |
ISO |
nickel sulfate results in decreased expression of GM2A mRNA nickel sulfate results in increased expression of GM2A mRNA |
CTD |
PMID:16780908 |
|
NCBI chr10:40,438,394...40,450,927
Ensembl chr10:40,438,356...40,450,930
|
|
G |
Gmpr |
guanosine monophosphate reductase |
increases expression |
ISO |
nickel sulfate results in increased expression of GMPR mRNA |
CTD |
PMID:22714537 |
|
NCBI chr17:19,543,274...19,580,929
Ensembl chr17:19,543,275...19,580,929
|
|
G |
Gna15 |
G protein subunit alpha 15 |
increases expression |
ISO |
nickel sulfate results in increased expression of GNA15 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 7:11,054,249...11,075,152
Ensembl chr 7:11,054,333...11,077,251
|
|
G |
Gnal |
G protein subunit alpha L |
increases expression |
ISO |
nickel sulfate results in increased expression of GNAL mRNA |
CTD |
PMID:22714537 |
|
NCBI chr18:62,805,406...62,946,133
Ensembl chr18:62,805,410...62,944,630
|
|
G |
Gnaz |
G protein subunit alpha z |
increases expression |
ISO |
nickel sulfate results in increased expression of GNAZ mRNA |
CTD |
PMID:22714537 |
|
NCBI chr20:14,593,072...14,644,020
Ensembl chr20:14,593,819...14,620,019
|
|
G |
Gnb2 |
G protein subunit beta 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of GNB2 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr12:22,229,079...22,234,096
Ensembl chr12:22,229,079...22,234,096
|
|
G |
Gng11 |
G protein subunit gamma 11 |
increases expression |
ISO |
nickel sulfate results in increased expression of GNG11 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:28,989,170...28,994,610
Ensembl chr 4:28,989,115...28,993,621 Ensembl chr 4:28,989,115...28,993,621
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|
G |
Gp9 |
glycoprotein IX (platelet) |
increases expression |
ISO |
nickel sulfate results in increased expression of GP9 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 4:119,680,671...119,682,006
Ensembl chr 4:119,680,112...119,682,547
|
|
G |
Gpat3 |
glycerol-3-phosphate acyltransferase 3 |
increases expression |
ISO |
nickel sulfate results in increased expression of GPAT3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr14:10,343,287...10,396,565
Ensembl chr14:10,343,282...10,395,047
|
|
G |
Gpatch2l |
G patch domain containing 2-like |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GPATCH2L mRNA |
CTD |
PMID:16780908 |
|
NCBI chr 6:110,093,767...110,228,943
Ensembl chr 6:110,093,819...110,227,475
|
|
G |
Gpc4 |
glypican 4 |
increases expression |
ISO |
nickel sulfate results in increased expression of GPC4 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr X:139,354,325...139,464,876
Ensembl chr X:139,354,155...139,464,798
|
|
G |
Gper1 |
G protein-coupled estrogen receptor 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of GPER1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
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G |
Gphn |
gephyrin |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GPHN mRNA |
CTD |
PMID:22714537 |
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NCBI chr 6:101,327,874...101,859,169
Ensembl chr 6:101,532,518...101,859,164
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G |
Gpm6b |
glycoprotein m6b |
increases expression |
ISO |
nickel sulfate results in increased expression of GPM6B mRNA |
CTD |
PMID:17382205 |
|
NCBI chr X:29,604,607...29,751,174
Ensembl chr X:29,607,075...29,648,403
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G |
Gpnmb |
glycoprotein nmb |
increases expression |
ISO |
nickel sulfate results in increased expression of GPNMB mRNA |
CTD |
PMID:16314067 PMID:22714537 |
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NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
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G |
Gpr39 |
G protein-coupled receptor 39 |
increases expression |
ISO |
nickel sulfate results in increased expression of GPR39 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr13:42,008,642...42,220,737
Ensembl chr13:42,008,842...42,009,738
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G |
Gpr4 |
G protein-coupled receptor 4 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GPR4 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:80,125,639...80,136,786
Ensembl chr 1:80,135,391...80,136,880
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G |
Gprc5b |
G protein-coupled receptor, class C, group 5, member B |
increases expression |
ISO |
nickel sulfate results in increased expression of GPRC5B mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:188,688,743...188,713,724
Ensembl chr 1:188,688,743...188,713,280
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G |
Gpt |
glutamic--pyruvic transaminase |
increases activity multiple interactions |
EXP ISO |
nickel sulfate results in increased activity of GPT protein puerarin inhibits the reaction [nickel sulfate results in increased activity of GPT protein] troxerutin inhibits the reaction [nickel sulfate results in increased activity of GPT protein] |
CTD |
PMID:24112957 PMID:26607348 |
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NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
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G |
Gpx3 |
glutathione peroxidase 3 |
increases expression |
ISO |
nickel sulfate results in increased expression of GPX3 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
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G |
Gpx4 |
glutathione peroxidase 4 |
increases expression multiple interactions |
ISO EXP |
nickel sulfate results in increased expression of GPX4 mRNA [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of GPX4 mRNA |
CTD |
PMID:18651567 PMID:31734292 |
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NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
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G |
Gpx7 |
glutathione peroxidase 7 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GPX7 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 5:128,001,766...128,009,610
Ensembl chr 5:128,001,761...128,009,735
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G |
Gramd1c |
GRAM domain containing 1C |
increases expression |
ISO |
nickel sulfate results in increased expression of GRAMD1C mRNA |
CTD |
PMID:22714537 |
|
NCBI chr11:61,609,370...61,659,355 NCBI chr11:62,580,983...62,634,961
Ensembl chr11:61,605,937...62,634,803
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G |
Grem1 |
gremlin 1, DAN family BMP antagonist |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GREM1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
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G |
Gse1 |
Gse1 coiled-coil protein |
increases expression |
ISO |
nickel sulfate results in increased expression of GSE1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr19:53,799,945...54,153,732
Ensembl chr19:54,060,622...54,148,970
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
increases expression |
ISO |
nickel sulfate results in increased expression of GSK3B mRNA |
CTD |
PMID:17374397 |
|
NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
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G |
Gsn |
gelsolin |
increases expression |
ISO |
nickel sulfate results in increased expression of GSN mRNA |
CTD |
PMID:18651567 |
|
NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
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G |
Gspt2 |
G1 to S phase transition 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GSPT2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr X:63,959,131...63,961,652
Ensembl chr X:63,954,727...63,961,613
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G |
Gsr |
glutathione-disulfide reductase |
increases expression decreases activity multiple interactions |
ISO EXP |
nickel sulfate results in increased expression of GSR mRNA nickel sulfate results in decreased activity of GSR protein naringin inhibits the reaction [nickel sulfate results in decreased activity of GSR protein] |
CTD |
PMID:20566472 PMID:20950607 |
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NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
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G |
Gtf2b |
general transcription factor IIB |
increases expression |
ISO |
nickel sulfate results in increased expression of GTF2B mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 2:248,709,433...248,727,741
Ensembl chr 2:248,715,281...248,727,741
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G |
Gtpbp6 |
GTP binding protein 6 (putative) |
increases expression |
ISO |
nickel sulfate results in increased expression of GTPBP6 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr12:52,637,000...52,640,869
Ensembl chr12:52,637,000...52,640,839 Ensembl chr12:52,637,000...52,640,839
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G |
Guk1 |
guanylate kinase 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of GUK1 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr10:45,535,617...45,552,455
Ensembl chr10:45,535,627...45,543,897
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G |
Gulp1 |
GULP PTB domain containing engulfment adaptor 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of GULP1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 9:51,263,484...51,538,066
Ensembl chr 9:51,263,622...51,538,072
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G |
Gzf1 |
GDNF-inducible zinc finger protein 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GZF1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 3:143,003,706...143,015,906
Ensembl chr 3:143,003,796...143,015,904
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G |
Gzmf |
granzyme F |
decreases expression |
ISO |
nickel sulfate results in decreased expression of GZMF mRNA |
CTD |
PMID:16166746 |
|
NCBI chr15:35,182,405...35,195,725
Ensembl chr15:35,184,364...35,195,725
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G |
H1f0 |
H1.0 linker histone |
decreases expression |
ISO |
nickel sulfate results in decreased expression of H1-0 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 7:120,260,776...120,262,636
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|
G |
H1f10 |
H1.10 linker histone |
increases expression |
ISO |
nickel sulfate results in increased expression of H1-10 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr 4:119,889,016...119,892,661
Ensembl chr 4:119,889,371...119,889,949
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G |
H3f4 |
H3.4 histone |
increases methylation |
ISO EXP |
nickel sulfate results in increased methylation of H3-4 protein nickel sulfate results in increased methylation of H3F4 protein |
CTD |
PMID:19371620 |
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NCBI chr10:45,304,696...45,305,106
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G |
Hacd4 |
3-hydroxyacyl-CoA dehydratase 4 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of HACD4 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 5:106,728,401...106,758,068
Ensembl chr 5:106,732,513...106,758,032
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G |
Hba-a1 |
hemoglobin alpha, adult chain 1 |
affects expression |
ISO |
nickel sulfate affects the expression of HBA-A1 mRNA |
CTD |
PMID:12718980 |
|
NCBI chr10:15,602,794...15,603,649
Ensembl chr10:15,602,794...15,603,649
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G |
Heatr5b |
HEAT repeat containing 5B |
decreases expression |
ISO |
nickel sulfate results in decreased expression of HEATR5B mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 6:1,330,314...1,410,339
Ensembl chr 6:1,330,314...1,410,339
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G |
Herc4 |
HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of HERC4 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr20:26,755,948...26,831,267
Ensembl chr20:26,755,911...26,830,931
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G |
Herc6 |
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
increases expression |
ISO |
nickel sulfate results in increased expression of HERC6 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:88,606,851...88,649,424
Ensembl chr 4:88,607,518...88,649,216
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G |
Hes1 |
hes family bHLH transcription factor 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of HES1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
increases expression increases stability decreases hydroxylation decreases expression multiple interactions |
ISO |
nickel sulfate results in increased expression of HIF1A mRNA; nickel sulfate results in increased expression of HIF1A protein nickel sulfate results in increased stability of HIF1A protein nickel sulfate results in decreased hydroxylation of HIF1A protein nickel sulfate results in decreased expression of HIF1A mRNA [chromium hexavalent ion co-treated with nickel sulfate] results in increased expression of HIF1A protein; [HIF1A mRNA co-treated with EPAS1 mRNA] affects the reaction [nickel sulfate results in decreased expression of USP28 protein]; [HIF1A mRNA co-treated with EPAS1 mRNA] affects the reaction [nickel sulfate results in increased degradation of MYC protein]; [macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in decreased expression of HIF1A mRNA; [nickel sulfate co-treated with Dinoprostone] results in increased expression of HIF1A protein; [nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of HIF1A protein; [potassium chromate(VI) co-treated with nickel sulfate] results in increased expression of HIF1A protein; [U 0126 co-treated with SB 203580] inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of HIF1A protein]; Ascorbic Acid inhibits the reaction [nickel sulfate results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of HIF1A protein]; Ascorbic Acid inhibits the reaction [nickel sulfate results in increased stability of HIF1A protein]; Dinoprostone promotes the reaction [nickel sulfate results in increased expression of and results in increased activity of HIF1A protein]; HIF1A mRNA affects the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of IL6 protein]; HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of PTGS2 mRNA]; HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of PTGS2 protein]; HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of CXCL1 protein]; HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of CXCL5 protein]; HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of CXCL8 protein]; HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of VEGFA protein]; HIF1A protein promotes the reaction [[nickel sulfate co-treated with Dinoprostone] results in increased secretion of CXCL8 protein]; macrophage stimulatory lipopeptide 2 co-treated with [nickel sulfate results in increased expression of HIF1A protein]; nickel sulfate affects the localization of and results in increased stability of HIF1A protein; nickel sulfate promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; nickel sulfate results in increased expression of and results in increased activity of HIF1A protein; SB 203580 inhibits the reaction [[nickel sulfate co-treated with Dinoprostone] results in increased expression of HIF1A protein]; SB 203580 inhibits the reaction [nickel sulfate results in increased expression of HIF1A protein]; U 0126 inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of HIF1A protein] |
CTD |
PMID:16288478 PMID:16314067 PMID:17382205 PMID:18832182 PMID:19074761 PMID:20046830 PMID:20600219 PMID:23526216 PMID:23568779 |
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NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
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G |
Hilpda |
hypoxia inducible lipid droplet-associated |
increases expression |
ISO |
nickel sulfate results in increased expression of HILPDA mRNA |
CTD |
PMID:17382205 |
|
NCBI chr 4:56,547,600...56,550,584
Ensembl chr 4:56,549,739...56,549,993
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G |
Hint3 |
histidine triad nucleotide binding protein 3 |
increases expression |
ISO |
nickel sulfate results in increased expression of HINT3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:29,413,425...29,423,288
Ensembl chr 1:29,413,365...29,423,347
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G |
Hip1 |
huntingtin interacting protein 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of HIP1 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr12:24,180,795...24,315,373
Ensembl chr12:24,180,937...24,315,373
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G |
Hipk2 |
homeodomain interacting protein kinase 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of HIPK2 mRNA |
CTD |
PMID:16314067 |
|
NCBI chr 4:66,438,390...66,625,183
Ensembl chr 4:66,445,266...66,624,912
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G |
Hist2h2aa3 |
histone cluster 2 H2A family member A3 |
increases expression |
ISO |
nickel sulfate results in increased expression of H2AC18 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr 2:198,388,766...198,389,293
Ensembl chr 2:198,388,809...198,389,201 Ensembl chr 2:198,388,809...198,389,201
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G |
Hivep1 |
HIVEP zinc finger 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of HIVEP1 mRNA |
CTD |
PMID:16780908 PMID:22714537 |
|
NCBI chr17:22,278,103...22,403,362
Ensembl chr17:22,278,798...22,311,392
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G |
Hk2 |
hexokinase 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of HK2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243
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G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of HMGCS1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
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G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions decreases expression |
ISO |
nickel sulfate results in increased expression of HMOX1 mRNA Quercetin inhibits the reaction [nickel sulfate results in decreased expression of HMOX1 protein] |
CTD |
PMID:16314067 PMID:19033392 PMID:20146380 PMID:20491607 PMID:20566472 PMID:25957741 |
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NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
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G |
Hnrnpa1 |
heterogeneous nuclear ribonucleoprotein A1 |
increases expression |
ISO |
nickel sulfate results in increased expression of HNRNPA1 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr 7:144,865,302...144,871,592
Ensembl chr 7:144,865,608...144,871,585
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G |
Homer1 |
homer scaffold protein 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of HOMER1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:22,909,550...23,012,303
Ensembl chr 2:22,909,569...23,009,678
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G |
Hoxa1 |
homeobox A1 |
increases expression |
ISO |
nickel sulfate results in increased expression of HOXA1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:82,124,358...82,127,182
Ensembl chr 4:82,125,406...82,127,066
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G |
Hoxa2 |
homeobox A2 |
increases expression |
ISO |
nickel sulfate results in increased expression of HOXA2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:82,130,441...82,134,846
Ensembl chr 4:82,131,329...82,133,605
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G |
Hoxa3 |
homeobox A3 |
increases expression |
ISO |
nickel sulfate results in increased expression of HOXA3 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 4:82,137,802...82,181,836
Ensembl chr 4:82,138,683...82,141,385
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G |
Hoxc10 |
homeo box C10 |
increases expression |
ISO |
nickel sulfate results in increased expression of HOXC10 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 7:144,577,578...144,582,802
Ensembl chr 7:144,577,465...144,582,622
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G |
Hoxc13 |
homeobox C13 |
increases expression |
ISO |
nickel sulfate results in increased expression of HOXC13 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 7:144,531,814...144,538,298
Ensembl chr 7:144,531,814...144,537,966
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G |
Hoxc9 |
homeobox C9 |
increases expression |
ISO |
nickel sulfate results in increased expression of HOXC9 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 7:144,592,462...144,598,807
Ensembl chr 7:144,595,960...144,598,632
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G |
Hpcal1 |
hippocalcin-like 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of HPCAL1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 6:43,001,920...43,109,083
Ensembl chr 6:43,001,948...43,109,071
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G |
Hpgd |
15-hydroxyprostaglandin dehydrogenase |
decreases expression |
ISO |
nickel sulfate results in decreased expression of HPGD mRNA |
CTD |
PMID:18651567 |
|
NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
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G |
Hprt1 |
hypoxanthine phosphoribosyltransferase 1 |
affects expression |
ISO |
nickel sulfate affects the expression of HPRT1 mRNA |
CTD |
PMID:18202158 |
|
NCBI chr X:158,196,640...158,228,815
Ensembl chr X:158,197,149...158,228,749 Ensembl chr X:158,197,149...158,228,749
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G |
Hps5 |
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of HPS5 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:102,810,114...102,849,430
Ensembl chr 1:102,776,082...102,849,430
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G |
Hs6st1 |
heparan sulfate 6-O-sulfotransferase 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of HS6ST1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 9:42,620,006...42,659,184
Ensembl chr 9:42,620,006...42,659,184
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G |
Hsd17b3 |
hydroxysteroid (17-beta) dehydrogenase 3 |
multiple interactions decreases expression |
EXP |
[CGA protein co-treated with nickel sulfate] results in decreased expression of HSD17B3 mRNA; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of HSD17B3 mRNA]; pyrazolanthrone inhibits the reaction [nickel sulfate results in decreased expression of HSD17B3 mRNA]; SB 203580 inhibits the reaction [nickel sulfate results in decreased expression of HSD17B3 mRNA]; U 0126 inhibits the reaction [nickel sulfate results in decreased expression of HSD17B3 mRNA] |
CTD |
PMID:29567110 |
|
NCBI chr17:1,579,319...1,610,745
Ensembl chr17:1,579,319...1,610,745
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G |
Hsd17b6 |
hydroxysteroid (17-beta) dehydrogenase 6 |
increases expression |
ISO |
nickel sulfate results in increased expression of HSD17B6 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 7:2,412,370...2,431,249
Ensembl chr 7:2,412,363...2,431,197 Ensembl chr13:2,412,363...2,431,197
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G |
Hsd17b7 |
hydroxysteroid (17-beta) dehydrogenase 7 |
multiple interactions |
EXP |
[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of HSD17B7 mRNA |
CTD |
PMID:31734292 |
|
NCBI chr13:88,288,116...88,308,019
Ensembl chr13:88,288,046...88,307,988
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G |
Hsdl1 |
hydroxysteroid dehydrogenase like 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of HSDL1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr19:52,209,403...52,225,486
Ensembl chr19:52,210,859...52,217,728
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G |
Hsf1 |
heat shock transcription factor 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of HSF1 mRNA |
CTD |
PMID:18651567 |
|
NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
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G |
Hspa12a |
heat shock protein family A (Hsp70) member 12A |
increases expression |
ISO |
nickel sulfate results in increased expression of HSPA12A mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 1:279,946,809...280,104,366
Ensembl chr 1:279,946,811...280,015,358
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G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
increases expression |
ISO |
nickel sulfate results in increased expression of HSPA1A mRNA |
CTD |
PMID:18651567 |
|
NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions increases expression |
EXP |
Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of HSPA5 protein]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of HSPA5 mRNA]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of HSPA5 protein] nickel sulfate results in increased expression of HSPA5 mRNA; nickel sulfate results in increased expression of HSPA5 protein |
CTD |
PMID:28296042 |
|
NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
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G |
Hspb8 |
heat shock protein family B (small) member 8 |
increases expression |
ISO |
nickel sulfate results in increased expression of HSPB8 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr12:45,905,371...45,920,014
Ensembl chr12:45,905,371...45,920,013
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G |
Hspg2 |
heparan sulfate proteoglycan 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of HSPG2 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 5:155,812,096...155,913,751
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G |
Htatip2 |
HIV-1 Tat interactive protein 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of HTATIP2 mRNA |
CTD |
PMID:16314067 |
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NCBI chr 1:105,094,272...105,109,459
Ensembl chr 1:105,094,411...105,109,461
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G |
Htr1d |
5-hydroxytryptamine receptor 1D |
increases expression |
ISO |
nickel sulfate results in increased expression of HTR1D mRNA |
CTD |
PMID:22714537 |
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NCBI chr 5:154,780,958...154,801,505
Ensembl chr 5:154,800,226...154,801,350
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G |
Htr7 |
5-hydroxytryptamine receptor 7 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of HTR7 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
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G |
Icam1 |
intercellular adhesion molecule 1 |
increases expression affects expression |
EXP ISO |
nickel sulfate results in increased expression of ICAM1 mRNA nickel sulfate results in increased expression of ICAM1 protein nickel sulfate affects the expression of ICAM1 mRNA |
CTD |
PMID:11114790 PMID:18202158 PMID:19702435 PMID:20417223 PMID:29540657 |
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NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
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G |
Id1 |
inhibitor of DNA binding 1, HLH protein |
increases expression |
ISO |
nickel sulfate results in increased expression of ID1 mRNA |
CTD |
PMID:18651567 |
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NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
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G |
Id2 |
inhibitor of DNA binding 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of ID2 mRNA |
CTD |
PMID:16780908 PMID:20146380 |
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NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
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G |
Id3 |
inhibitor of DNA binding 3, HLH protein |
increases expression |
ISO |
nickel sulfate results in increased expression of ID3 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 5:154,489,603...154,491,172
Ensembl chr 5:154,489,590...154,491,223
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G |
Id4 |
inhibitor of DNA binding 4, HLH protein |
increases expression |
ISO |
nickel sulfate results in increased expression of ID4 mRNA |
CTD |
PMID:22714537 |
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NCBI chr17:16,692,557...16,695,126
Ensembl chr17:16,692,557...16,695,126
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G |
Idh3b |
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta |
decreases expression |
ISO |
nickel sulfate results in decreased expression of IDH3B mRNA |
CTD |
PMID:22714537 |
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NCBI chr 3:122,808,564...122,813,638
Ensembl chr 3:122,808,564...122,813,583
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G |
Ido1 |
indoleamine 2,3-dioxygenase 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of IDO1 mRNA |
CTD |
PMID:16780908 |
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NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
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G |
Ids |
iduronate 2-sulfatase |
decreases expression |
ISO |
nickel sulfate results in decreased expression of IDS mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 8:69,447,971...69,466,708
Ensembl chr 8:69,449,801...69,466,618
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G |
Ier2 |
immediate early response 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of IER2 mRNA |
CTD |
PMID:16780908 |
|
NCBI chr19:25,774,146...25,775,670
Ensembl chr19:25,774,143...25,775,659
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G |
Ier3 |
immediate early response 3 |
increases expression |
ISO |
nickel sulfate results in increased expression of IER3 mRNA |
CTD |
PMID:17374397 PMID:18651567 PMID:22714537 |
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NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
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G |
Ifi30 |
IFI30, lysosomal thiol reductase |
increases expression |
ISO |
nickel sulfate results in increased expression of IFI30 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr16:20,426,566...20,430,772
Ensembl chr16:20,426,566...20,430,752
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G |
Ifi44 |
interferon-induced protein 44 |
increases expression |
ISO |
nickel sulfate results in increased expression of IFI44 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 2:256,897,765...256,915,591
Ensembl chr 2:256,897,772...256,915,569
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G |
Ifih1 |
interferon induced with helicase C domain 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of IFIH1 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 3:48,557,696...48,604,097
Ensembl chr 3:48,557,696...48,604,097
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G |
Ifit2 |
interferon-induced protein with tetratricopeptide repeats 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of IFIT2 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 1:252,894,663...252,900,727
Ensembl chr 1:252,894,663...252,900,726
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G |
Ifnb1 |
interferon beta 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of IFNB1 mRNA |
CTD |
PMID:20525893 |
|
NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
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G |
Ifne |
interferon, epsilon |
decreases expression |
ISO |
nickel sulfate results in decreased expression of IFNE mRNA |
CTD |
PMID:22714537 |
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NCBI chr 5:107,178,124...107,203,908
Ensembl chr 5:107,233,230...107,233,799
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G |
Ifng |
interferon gamma |
multiple interactions increases secretion affects expression increases expression |
ISO |
[nickel sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; Cholecalciferol inhibits the reaction [nickel sulfate results in increased secretion of IFNG protein]; Cyclosporine inhibits the reaction [nickel sulfate results in increased secretion of IFNG protein]; Dimethyl Fumarate inhibits the reaction [nickel sulfate results in increased secretion of IFNG protein]; Hydrocortisone inhibits the reaction [nickel sulfate results in increased secretion of IFNG protein]; IFNG protein promotes the reaction [nickel sulfate results in increased expression of IL27 mRNA]; Zinc Sulfate inhibits the reaction [nickel sulfate results in increased secretion of IFNG protein] nickel sulfate affects the expression of IFNG mRNA nickel sulfate results in increased expression of IFNG mRNA |
CTD |
PMID:10929769 PMID:11145678 PMID:14650623 PMID:15270870 PMID:15663561 PMID:16166746 PMID:29594315 PMID:30421605 |
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NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
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G |
Ifrd1 |
interferon-related developmental regulator 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of IFRD1 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
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G |
Ift88 |
intraflagellar transport 88 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of IFT88 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr15:37,690,417...37,786,855
Ensembl chr15:37,691,345...37,784,924
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G |
Igf2bp1 |
insulin-like growth factor 2 mRNA binding protein 1 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of IGF2BP1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr10:83,774,178...83,823,323
Ensembl chr10:83,780,203...83,822,996
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G |
Igfbp4 |
insulin-like growth factor binding protein 4 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of IGFBP4 mRNA |
CTD |
PMID:22714537 |
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NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578
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G |
Igfbp6 |
insulin-like growth factor binding protein 6 |
decreases expression increases expression |
ISO |
nickel sulfate results in decreased expression of IGFBP6 mRNA nickel sulfate results in increased expression of IGFBP6 mRNA |
CTD |
PMID:16100012 PMID:16780908 PMID:17374397 |
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NCBI chr 7:143,749,385...143,754,018
Ensembl chr 7:143,749,221...143,754,054
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G |
Il10 |
interleukin 10 |
increases secretion increases expression |
ISO |
nickel sulfate results in increased secretion of IL10 protein nickel sulfate results in increased expression of IL10 mRNA |
CTD |
PMID:11145678 PMID:15347381 |
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NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
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G |
Il11 |
interleukin 11 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of IL11 mRNA |
CTD |
PMID:22714537 |
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NCBI chr 1:72,636,959...72,643,255
Ensembl chr 1:72,635,267...72,643,255
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G |
Il12a |
interleukin 12A |
increases expression |
ISO |
nickel sulfate results in increased expression of IL12A mRNA |
CTD |
PMID:30421605 |
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NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
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G |
Il12b |
interleukin 12B |
affects expression increases expression increases secretion multiple interactions |
ISO |
nickel sulfate affects the expression of IL12B mRNA nickel sulfate results in increased expression of IL12B mRNA; nickel sulfate results in increased expression of IL12B protein nickel sulfate results in increased secretion of IL12B protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [nickel sulfate results in increased secretion of IL12B protein]; BAY 11-7085 inhibits the reaction [nickel sulfate results in increased secretion of IL12B protein]; pyrazolanthrone inhibits the reaction [nickel sulfate results in increased secretion of IL12B protein]; SB 203580 inhibits the reaction [nickel sulfate results in increased secretion of IL12B protein] |
CTD |
PMID:17636246 PMID:18202158 PMID:19101624 PMID:20525893 PMID:25673294 PMID:30421605 |
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NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
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G |
Il13ra1 |
interleukin 13 receptor subunit alpha 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of IL13RA1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr X:122,724,081...122,783,801
Ensembl chr X:122,724,129...122,781,479
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G |
Il15 |
interleukin 15 |
affects expression |
ISO |
nickel sulfate affects the expression of IL15 mRNA |
CTD |
PMID:18202158 |
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NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594
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G |
Il18 |
interleukin 18 |
decreases expression increases expression |
ISO |
nickel sulfate results in decreased expression of IL18 mRNA nickel sulfate results in increased expression of IL18 protein |
CTD |
PMID:18651567 PMID:23063874 |
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NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
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G |
Il1a |
interleukin 1 alpha |
increases secretion multiple interactions |
ISO |
nickel sulfate results in increased secretion of IL1A protein IL1A protein affects the reaction [nickel sulfate results in increased secretion of CCL20 protein]; IL1A protein affects the reaction [nickel sulfate results in increased secretion of CXCL8 protein] |
CTD |
PMID:15679580 |
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NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
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G |
Il1b |
interleukin 1 beta |
increases expression decreases expression multiple interactions increases secretion |
EXP ISO |
nickel sulfate results in increased expression of IL1B mRNA nickel sulfate results in decreased expression of IL1B mRNA Quercetin inhibits the reaction [nickel sulfate results in increased expression of IL1B protein] nickel sulfate results in increased expression of IL1B mRNA; nickel sulfate results in increased expression of IL1B protein [Tetradecanoylphorbol Acetate co-treated with nickel sulfate] results in increased expression of and results in increased secretion of IL1B protein; Zinc Sulfate inhibits the reaction [nickel sulfate results in increased secretion of IL1B protein] |
CTD |
PMID:11033066 PMID:11114790 PMID:11751209 PMID:14650623 PMID:16166746 PMID:16314067 PMID:16780908 PMID:19702435 PMID:20713136 PMID:21697260 PMID:24964617 PMID:25673294 PMID:25957741 PMID:29594315 PMID:30842373 |
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NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
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G |
Il1r1 |
interleukin 1 receptor type 1 |
increases expression |
ISO |
nickel sulfate results in increased expression of IL1R1 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
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G |
Il1r2 |
interleukin 1 receptor type 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of IL1R2 mRNA |
CTD |
PMID:16166746 PMID:16780908 |
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NCBI chr 9:46,840,646...46,881,241
Ensembl chr 9:46,840,992...46,881,264
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G |
Il1rn |
interleukin 1 receptor antagonist |
increases expression |
ISO |
nickel sulfate results in increased expression of IL1RN mRNA |
CTD |
PMID:16166746 PMID:16780908 |
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NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
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G |
Il2 |
interleukin 2 |
increases secretion multiple interactions increases expression |
ISO |
nickel sulfate results in increased secretion of IL2 protein [nickel sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA nickel sulfate results in increased expression of IL2 protein |
CTD |
PMID:12925207 PMID:22381623 PMID:29594315 |
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NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
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G |
Il23a |
interleukin 23 subunit alpha |
increases expression |
ISO |
nickel sulfate results in increased expression of IL23A mRNA |
CTD |
PMID:30421605 |
|
NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
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G |
Il24 |
interleukin 24 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of IL24 mRNA |
CTD |
PMID:22714537 |
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NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
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G |
Il27 |
interleukin 27 |
increases expression multiple interactions |
ISO |
nickel sulfate results in increased expression of IL27 mRNA BAY 11-7085 inhibits the reaction [nickel sulfate results in increased expression of IL27 mRNA]; IFNG protein promotes the reaction [nickel sulfate results in increased expression of IL27 mRNA]; Janus Kinase Inhibitors inhibits the reaction [nickel sulfate results in increased secretion of IL27 mRNA]; SB 203580 inhibits the reaction [nickel sulfate results in increased expression of IL27 mRNA]; TLR4 protein affects the reaction [nickel sulfate results in increased expression of IL27 mRNA] |
CTD |
PMID:30421605 |
|
NCBI chr 1:198,003,615...198,010,112
Ensembl chr 1:198,003,683...198,008,893
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G |
Il4 |
interleukin 4 |
increases secretion increases expression |
ISO |
nickel sulfate results in increased secretion of IL4 protein nickel sulfate results in increased expression of IL4 mRNA |
CTD |
PMID:10929769 PMID:11145678 |
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NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
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G |
Il4r |
interleukin 4 receptor |
increases expression |
ISO |
nickel sulfate results in increased expression of IL4RA mRNA; nickel sulfate results in increased expression of IL4RA protein |
CTD |
PMID:16100012 PMID:22381623 |
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NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
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G |
Il5 |
interleukin 5 |
multiple interactions increases secretion |
ISO |
Cyclosporine inhibits the reaction [nickel sulfate results in increased secretion of IL5 protein]; Diclofenac inhibits the reaction [nickel sulfate results in increased secretion of IL5 protein]; Hydrocortisone inhibits the reaction [nickel sulfate results in increased secretion of IL5 protein] |
CTD |
PMID:10929769 PMID:15270870 PMID:15347381 PMID:15663561 PMID:19572476 |
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NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
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G |
Il6 |
interleukin 6 |
increases expression multiple interactions increases secretion |
EXP ISO |
nickel sulfate results in increased expression of IL6 mRNA puerarin inhibits the reaction [nickel sulfate results in increased expression of IL6 protein] nickel sulfate results in increased secretion of IL6 protein nickel sulfate results in increased expression of IL6 mRNA; nickel sulfate results in increased expression of IL6 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of IL6 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [nickel sulfate results in increased secretion of IL6 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of IL6 protein]; [macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of IL6 mRNA; [nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of IL6 mRNA; [nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with nickel sulfate] results in increased expression of and results in increased secretion of IL6 protein; BAY 11-7085 inhibits the reaction [nickel sulfate results in increased secretion of IL6 protein]; HIF1A mRNA affects the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of IL6 protein]; nickel sulfate results in increased expression of and results in increased secretion of IL6 protein; PTGS2 mRNA affects the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of IL6 protein]; pyrazolanthrone inhibits the reaction [nickel sulfate results in increased secretion of IL6 protein]; SB 203580 inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of IL6 protein]; SB 203580 inhibits the reaction [nickel sulfate results in increased secretion of IL6 protein]; U 0126 inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of IL6 protein] |
CTD |
PMID:11033066 PMID:11114790 PMID:16166746 PMID:16780908 PMID:17118622 PMID:17636246 PMID:17763283 PMID:18832182 PMID:19101624 PMID:20600219 PMID:22714537 PMID:24964617 PMID:25673294 PMID:26607348 |
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NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
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G |
Il7r |
interleukin 7 receptor |
increases expression |
ISO |
nickel sulfate results in increased expression of IL7R mRNA |
CTD |
PMID:16780908 PMID:22714537 |
|
|
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G |
Ildr2 |
immunoglobulin-like domain containing receptor 2 |
decreases expression |
ISO |
nickel sulfate results in decreased expression of ILDR2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr13:84,474,191...84,532,347
Ensembl chr13:84,474,319...84,530,031
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G |
Ilrun |
inflammation and lipid regulator with UBA-like and NBR1-like domains |
increases expression |
ISO |
nickel sulfate results in increased expression of ILRUN mRNA |
CTD |
PMID:22714537 |
|
NCBI chr20:7,331,321...7,397,588
Ensembl chr20:7,331,326...7,397,448
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G |
Impa2 |
inositol monophosphatase 2 |
increases expression |
ISO |
nickel sulfate results in increased expression of IMPA2 mRNA |
CTD |
PMID:22714537 |
|
NCBI chr18:63,016,577...63,050,123
Ensembl chr18:63,016,577...63,047,781
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