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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:famciclovir
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Accession:CHEBI:4974 term browser browse the term
Definition:2-Amino-9H-purine in which the hydrogen at position 9 is substituted by a 4-acetoxy-3-(acetoxymethyl)but-1-yl group. A prodrug of the antiviral penciclovir, it is used for the treatment of acute herpes zoster (shingles), for the treatment or suppression of recurrent genital herpes in immunocompetent patients and for the treatment of recurrent mucocutaneous herpes simplex infections in HIV infected patients.
Synonyms:exact_synonym: 2-[(acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate
 related_synonym: 2-(2-(2-amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate;   9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine;   BRL-42810;   FCV;   Famvir;   Formula=C14H19N5O4;   InChI=1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18);   InChIKey=GGXKWVWZWMLJEH-UHFFFAOYSA-N;   SMILES=CC(=O)OCC(CCn1cnc2cnc(N)nc12)COC(C)=O;   acetic acid 2-acetoxymethyl-4-(2-amino-purin-9-yl)-butyl ester;   famciclovirum
 alt_id: CHEBI:174284
 xref: CAS:104227-87-4;   DrugBank:DB00426;   Drug_Central:1128;   HMDB:HMDB0014570;   KEGG:D00317;   LINCS:LSM-2990;   PMID:17870541;   PMID:2754699;   PMID:9719596;   Patent:US5246937;   Reaxys:4208403;   Wikipedia:Famciclovir



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Path 1
Term Annotations click to browse term
  CHEBI ontology 19860
    role 19832
      application 19675
        pro-agent 11550
          prodrug 11310
            famciclovir 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19860
    subatomic particle 19858
      composite particle 19858
        hadron 19858
          baryon 19858
            nucleon 19858
              atomic nucleus 19858
                atom 19858
                  main group element atom 19804
                    p-block element atom 19804
                      carbon group element atom 19745
                        carbon atom 19741
                          organic molecular entity 19741
                            organic molecule 19692
                              organic cyclic compound 19503
                                organic heterocyclic compound 18875
                                  organic heteropolycyclic compound 18302
                                    organic heterobicyclic compound 17250
                                      imidazopyrimidine 7721
                                        purines 7720
                                          aminopurine 6726
                                            2-aminopurines 6300
                                              famciclovir 0
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