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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:copper(II) chloride
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Accession:CHEBI:49553 term browser browse the term
Definition:An inorganic chloride of copper in which the metal is in the +2 oxidation state.
Synonyms:exact_synonym: copper(2+) dichloride
 related_synonym: Coclor;   Copper bichloride;   Copper chloride;   Copper chloride (CuCl2);   Copper dichloride;   Copper(2+)chloride;   Copper(II) chloride (1:2);   CuCl2;   Cupric chloride;   Cupric chloride anhydrous;   Cupric dichloride;   Formula=Cl2Cu;   InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2;   InChIKey=ORTQZVOHEJQUHG-UHFFFAOYSA-L;   SMILES=Cl[Cu]Cl
 xref: Beilstein:8128168;   CAS:7447-39-4;   DrugBank:DB09131;   Drug_Central:4530;   Gmelin:9300
 xref_mesh: MESH:C029892
 xref: PDBeChem:CUL;   PMID:10444249;   PMID:9730919;   PPDB:174;   Reaxys:8128168;   Wikipedia:Copper(II)_chloride


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copper(II) chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase decreases expression EXP cupric chloride results in decreased expression of AASDHPPT mRNA CTD PMID:17211630 NCBI chr11:106,077,605...106,098,695
Ensembl chr11:106,075,501...106,098,699
JBrowse link
G ABCF3 ATP binding cassette subfamily F member 3 increases expression EXP cupric chloride results in increased expression of ABCF3 mRNA CTD PMID:17211630 NCBI chr 3:184,186,160...184,194,012
Ensembl chr 3:184,186,023...184,194,012
JBrowse link
G ABHD4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression EXP cupric chloride results in increased expression of ABHD4 mRNA CTD PMID:17211630 NCBI chr14:22,598,298...22,612,963
Ensembl chr14:22,598,237...22,613,215
JBrowse link
G ACHE acetylcholinesterase (Cartwright blood group) multiple interactions ISO cupric chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ACHE protein] CTD PMID:24799335 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G ACO1 aconitase 1 decreases expression ISO cupric chloride results in decreased expression of ACO1 protein CTD PMID:29617964 NCBI chr 9:32,384,643...32,454,769
Ensembl chr 9:32,384,603...32,454,769
JBrowse link
G ACTB actin beta increases expression ISO cupric chloride results in increased expression of ACTB protein CTD PMID:29617964 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
Ensembl chr 7:5,526,409...5,563,902
JBrowse link
G ADRM1 ADRM1 26S proteasome ubiquitin receptor increases expression EXP cupric chloride results in increased expression of ADRM1 mRNA CTD PMID:17211630 NCBI chr20:62,302,061...62,308,862
Ensembl chr20:62,302,093...62,308,862
JBrowse link
G AHSG alpha 2-HS glycoprotein decreases expression EXP cupric chloride results in decreased expression of AHSG mRNA CTD PMID:17211630 NCBI chr 3:186,613,060...186,621,318
Ensembl chr 3:186,613,060...186,621,318
JBrowse link
G AKR1A1 aldo-keto reductase family 1 member A1 increases expression ISO cupric chloride results in increased expression of AKR1A1 protein CTD PMID:29617964 NCBI chr 1:45,550,779...45,570,051
Ensembl chr 1:45,550,543...45,570,049
JBrowse link
G ALB albumin multiple interactions EXP ALB protein inhibits the reaction [cupric chloride results in decreased activity of PROC protein] CTD PMID:11820775 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G ALDH1L1 aldehyde dehydrogenase 1 family member L1 increases expression ISO cupric chloride results in increased expression of ALDH1L1 mRNA CTD PMID:17211630 NCBI chr 3:126,103,565...126,197,758
Ensembl chr 3:126,103,562...126,197,994
JBrowse link
G ALDOA aldolase, fructose-bisphosphate A increases expression EXP cupric chloride results in increased expression of ALDOA mRNA CTD PMID:17211630 NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457
Ensembl chr16:30,064,164...30,070,457
JBrowse link
G ALDOC aldolase, fructose-bisphosphate C decreases expression
increases expression
ISO cupric chloride results in decreased expression of ALDOC protein
cupric chloride results in increased expression of ALDOA protein
CTD PMID:29617964 NCBI chr17:28,573,115...28,576,963
Ensembl chr17:28,573,115...28,576,948
JBrowse link
G ALKBH2 alkB homolog 2, alpha-ketoglutarate dependent dioxygenase decreases activity EXP cupric chloride results in decreased activity of ALKBH2 protein CTD PMID:28926697 NCBI chr12:109,088,189...109,093,631
Ensembl chr12:109,088,188...109,093,631
JBrowse link
G ALKBH3 alkB homolog 3, alpha-ketoglutarate dependent dioxygenase decreases activity EXP cupric chloride results in decreased activity of ALKBH3 protein CTD PMID:28926697 NCBI chr11:43,880,831...43,920,274
Ensembl chr11:43,880,811...43,920,274
JBrowse link
G ANKRD1 ankyrin repeat domain 1 increases expression EXP cupric chloride results in increased expression of ANKRD1 mRNA CTD PMID:17211630 NCBI chr10:90,912,096...90,921,087
Ensembl chr10:90,912,096...90,921,087
Ensembl chr10:90,912,096...90,921,087
JBrowse link
G ANPEP alanyl aminopeptidase, membrane decreases expression EXP cupric chloride results in decreased expression of ANPEP mRNA CTD PMID:17211630 NCBI chr15:89,784,895...89,814,852
Ensembl chr15:89,784,895...89,815,401
JBrowse link
G APOM apolipoprotein M increases expression ISO cupric chloride results in increased expression of APOM mRNA CTD PMID:17211630 NCBI chr 6:31,652,404...31,658,210
Ensembl chr 6:31,652,416...31,658,210
JBrowse link
G APP amyloid beta precursor protein increases expression
multiple interactions
ISO cupric chloride results in increased expression of APP mRNA; cupric chloride results in increased expression of APP protein
cupric chloride results in decreased uptake of and results in decreased degradation of APP protein modified form; PP242 inhibits the reaction [cupric chloride results in decreased uptake of and results in decreased degradation of APP protein modified form]
CTD PMID:22542740 PMID:32512069 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
G AR androgen receptor multiple interactions EXP [Disulfiram co-treated with cupric chloride] results in decreased expression of AR protein CTD PMID:19789329 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619
JBrowse link
G ATF2 activating transcription factor 2 multiple interactions ISO [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein] CTD PMID:30768131 NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382
JBrowse link
G ATF4 activating transcription factor 4 multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA] CTD PMID:20920558 NCBI chr22:39,514,494...39,522,686
Ensembl chr22:39,519,672...39,522,683
Ensembl chr22:39,519,672...39,522,683
Ensembl chr22:39,519,672...39,522,683
JBrowse link
G ATM ATM serine/threonine kinase multiple interactions EXP cupric chloride results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:16959548 NCBI chr11:108,222,484...108,369,102
Ensembl chr11:108,222,832...108,369,102
Ensembl chr11:108,222,832...108,369,102
Ensembl chr11:108,222,832...108,369,102
JBrowse link
G ATOX1 antioxidant 1 copper chaperone multiple interactions EXP [cupric chloride results in increased abundance of Copper] which results in increased expression of ATOX1 mRNA; ATOX1 protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper] CTD PMID:32278528 NCBI chr 5:151,742,822...151,758,631
Ensembl chr 5:151,742,316...151,772,532
JBrowse link
G ATP7A ATPase copper transporting alpha increases transport
increases expression
multiple interactions
decreases glutathionylation
affects localization
EXP
ISO
ATP7A protein results in increased transport of cupric chloride
cupric chloride results in increased expression of ATP7A protein
cupric chloride inhibits the reaction [Cycloheximide results in decreased expression of ATP7A protein]; cupric chloride promotes the reaction [Deferoxamine results in increased expression of ATP7A mRNA]; Deferoxamine promotes the reaction [cupric chloride results in increased expression of ATP7A protein]
cupric chloride results in decreased glutathionylation of ATP7A protein
cupric chloride affects the localization of ATP7A protein
Omeprazole inhibits the reaction [cupric chloride affects the localization of ATP7A protein]
ATP7A protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper]; ATP7A protein results in decreased uptake of [cupric chloride results in increased abundance of Copper]; cupric chloride inhibits the reaction [bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]]; cupric chloride promotes the reaction [CLU protein binds to ATP7A protein]
CTD PMID:11092760 PMID:16317117 PMID:17009961 PMID:20566629 PMID:21242307 PMID:23174565 PMID:25337692 PMID:32278528 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,656...78,050,395
JBrowse link
G ATP7B ATPase copper transporting beta decreases response to substance
affects localization
multiple interactions
EXP
ISO
ATP7B protein results in decreased susceptibility to cupric chloride
cupric chloride affects the localization of ATP7B protein
ATP7B protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper]; ATP7B protein results in increased uptake of [cupric chloride results in increased abundance of Copper]; cupric chloride promotes the reaction [CLU protein binds to ATP7B protein]
CTD PMID:10728692 PMID:16799059 PMID:21242307 PMID:24343273 PMID:32278528 NCBI chr13:51,932,669...52,012,130
Ensembl chr13:51,930,436...52,012,125
JBrowse link
G BACE1 beta-secretase 1 increases expression ISO cupric chloride results in increased expression of BACE1 mRNA; cupric chloride results in increased expression of BACE1 protein CTD PMID:22542740 NCBI chr11:117,285,698...117,316,256
Ensembl chr11:117,285,207...117,316,259
Ensembl chr11:117,285,207...117,316,259
JBrowse link
G BAG3 BAG cochaperone 3 increases expression EXP cupric chloride results in increased expression of BAG3 mRNA CTD PMID:17211630 NCBI chr10:119,651,380...119,677,819
Ensembl chr10:119,651,370...119,677,819
Ensembl chr10:119,651,370...119,677,819
JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO
EXP
cupric chloride results in increased expression of BAX protein
[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein; [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased expression of BAX protein; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; Ethanol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; neocuproine inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; Thiourea inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]
CTD PMID:21035945 PMID:22239859 PMID:23313662 PMID:24170445 PMID:29803612 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression
ISO
EXP
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein]
[Disulfiram co-treated with cupric chloride] results in decreased expression of BCL2 protein
cupric chloride results in decreased expression of BCL2 protein
CTD PMID:20920558 PMID:21911303 PMID:23313662 PMID:24170445 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 decreases expression ISO cupric chloride results in decreased expression of BCL2L1 protein CTD PMID:23313662 PMID:24170445 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BID BH3 interacting domain death agonist increases expression EXP cupric chloride results in increased expression of BID mRNA CTD PMID:17211630 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770
JBrowse link
G BLVRB biliverdin reductase B increases expression EXP cupric chloride results in increased expression of BLVRB mRNA CTD PMID:17211630 NCBI chr19:40,447,768...40,465,745
Ensembl chr19:40,447,765...40,465,764
JBrowse link
G C1QTNF4 C1q and TNF related 4 increases expression ISO cupric chloride results in increased expression of C1QTNF4 mRNA CTD PMID:17211630 NCBI chr11:47,589,664...47,596,336
Ensembl chr11:47,589,667...47,594,411
JBrowse link
G CASP3 caspase 3 multiple interactions
increases expression
increases activity
decreases activity
ISO
EXP
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein; [Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein]
[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein; [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP3 protein; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; Ethanol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; neocuproine inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; Thiourea inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]
cupric chloride results in increased expression of CASP3 protein
cupric chloride results in increased activity of CASP3 protein
cupric chloride results in decreased activity of CASP3 protein
CTD PMID:11239917 PMID:18056745 PMID:20920558 PMID:21035945 PMID:22954531 PMID:23313662 PMID:24170445 PMID:29803612 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP7 caspase 7 multiple interactions ISO
EXP
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein]
[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP7 protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP7 protein]
CTD PMID:20920558 PMID:21035945 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
JBrowse link
G CASP8 caspase 8 increases expression ISO cupric chloride results in increased expression of CASP8 protein CTD PMID:23313662 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
G CASP9 caspase 9 multiple interactions
increases expression
ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein]
cupric chloride results in increased expression of CASP9 protein
CTD PMID:20920558 PMID:23313662 PMID:24170445 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase multiple interactions EXP CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein] CTD PMID:29803612 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCN1 cellular communication network factor 1 increases expression EXP cupric chloride results in increased expression of CCN1 mRNA CTD PMID:17211630 NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589
Ensembl chr 1:85,580,761...85,584,589
JBrowse link
G CCS copper chaperone for superoxide dismutase multiple interactions EXP cupric chloride results in increased degradation of and results in decreased expression of CCS protein CTD PMID:16531609 NCBI chr11:66,593,162...66,606,019
Ensembl chr11:66,593,153...66,606,019
JBrowse link
G CD63 CD63 molecule decreases expression EXP cupric chloride results in decreased expression of CD63 mRNA CTD PMID:17211630 NCBI chr12:55,725,323...55,729,673
Ensembl chr12:55,725,323...55,729,707
JBrowse link
G CDC34 cell division cycle 34, ubiqiutin conjugating enzyme affects expression EXP cupric chloride affects the expression of CDC34 mRNA CTD PMID:17211630 NCBI chr19:531,720...542,088
Ensembl chr19:531,760...542,092
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A affects expression EXP cupric chloride affects the expression of CDKN1A mRNA CTD PMID:17211630 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,339
Ensembl chr 6:36,676,460...36,687,339
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B affects expression ISO cupric chloride affects the expression of CDKN1B protein CTD PMID:23313662 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,715,058...12,722,369
Ensembl chr12:12,715,058...12,722,369
JBrowse link
G CHORDC1 cysteine and histidine rich domain containing 1 increases expression EXP cupric chloride results in increased expression of CHORDC1 mRNA CTD PMID:17211630 NCBI chr11:90,200,429...90,223,082
Ensembl chr11:90,200,429...90,223,077
JBrowse link
G CKMT2 creatine kinase, mitochondrial 2 decreases expression ISO cupric chloride results in decreased expression of CKMT2 protein CTD PMID:29617964 NCBI chr 5:81,233,322...81,266,398
Ensembl chr 5:81,233,320...81,266,398
JBrowse link
G CKS2 CDC28 protein kinase regulatory subunit 2 increases expression EXP cupric chloride results in increased expression of CKS2 mRNA CTD PMID:17211630 NCBI chr 9:89,311,195...89,316,703
Ensembl chr 9:89,311,195...89,316,703
JBrowse link
G CLCN6 chloride voltage-gated channel 6 increases expression EXP cupric chloride results in increased expression of CLCN6 mRNA CTD PMID:17211630 NCBI chr 1:11,806,191...11,843,130
Ensembl chr 1:11,806,096...11,848,079
JBrowse link
G CLCN7 chloride voltage-gated channel 7 affects expression EXP cupric chloride affects the expression of CLCN7 mRNA CTD PMID:17211630 NCBI chr16:1,444,935...1,475,028
Ensembl chr16:1,444,934...1,475,084
JBrowse link
G CLDND1 claudin domain containing 1 increases expression EXP cupric chloride results in increased expression of CLDND1 mRNA CTD PMID:17211630 NCBI chr 3:98,515,483...98,522,902
Ensembl chr 3:98,497,912...98,523,066
JBrowse link
G CLU clusterin multiple interactions
increases expression
EXP
ISO
cupric chloride promotes the reaction [CLU protein binds to ATP7A protein]; cupric chloride promotes the reaction [CLU protein binds to ATP7B protein]
cupric chloride results in increased expression of CLU mRNA
CTD PMID:17211630 PMID:21242307 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700
JBrowse link
G COMMD1 copper metabolism domain containing 1 decreases response to substance
multiple interactions
decreases expression
EXP
ISO
COMMD1 protein results in decreased susceptibility to cupric chloride
cupric chloride promotes the reaction [COMMD1 protein binds to SOD1 protein]
[COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK2 protein; [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein
cupric chloride results in decreased expression of COMMD1 mRNA; cupric chloride results in decreased expression of COMMD1 protein
CTD PMID:17211630 PMID:24691167 PMID:25007851 NCBI chr 2:61,888,391...62,136,066
Ensembl chr 2:61,888,724...62,147,247
JBrowse link
G COMMD10 COMM domain containing 10 decreases expression EXP cupric chloride results in decreased expression of COMMD10 mRNA CTD PMID:17211630 NCBI chr 5:116,085,025...116,293,287
Ensembl chr 5:116,085,016...116,412,762
JBrowse link
G COMMD2 COMM domain containing 2 decreases expression EXP cupric chloride results in decreased expression of COMMD2 mRNA CTD PMID:17211630 NCBI chr 3:149,738,472...149,752,489
Ensembl chr 3:149,738,472...149,752,495
JBrowse link
G COMMD3 COMM domain containing 3 decreases expression EXP cupric chloride results in decreased expression of COMMD3 mRNA CTD PMID:17211630 NCBI chr10:22,316,388...22,320,306
Ensembl chr10:22,316,386...22,320,306
JBrowse link
G COMMD4 COMM domain containing 4 decreases expression EXP cupric chloride results in decreased expression of COMMD4 mRNA CTD PMID:17211630 NCBI chr15:75,336,035...75,343,227
Ensembl chr15:75,336,020...75,343,224
JBrowse link
G COMMD5 COMM domain containing 5 decreases expression EXP cupric chloride results in decreased expression of COMMD5 mRNA CTD PMID:17211630 NCBI chr 8:144,837,978...144,853,556
Ensembl chr 8:144,841,042...144,853,736
JBrowse link
G COMMD6 COMM domain containing 6 decreases expression EXP cupric chloride results in decreased expression of COMMD6 mRNA CTD PMID:17211630 NCBI chr13:75,525,214...75,549,439
Ensembl chr13:75,525,219...75,549,439
Ensembl chr13:75,525,219...75,549,439
JBrowse link
G COMMD7 COMM domain containing 7 decreases expression EXP cupric chloride results in decreased expression of COMMD7 mRNA CTD PMID:17211630 NCBI chr20:32,702,691...32,743,472
Ensembl chr20:32,632,183...32,743,567
Ensembl chr20:32,632,183...32,743,567
Ensembl chr20:32,632,183...32,743,567
JBrowse link
G COMMD8 COMM domain containing 8 decreases expression EXP cupric chloride results in decreased expression of COMMD8 mRNA CTD PMID:17211630 NCBI chr 4:47,450,787...47,463,702
Ensembl chr 4:47,450,787...47,463,702
JBrowse link
G COX16 cytochrome c oxidase assembly factor COX16 affects expression EXP cupric chloride affects the expression of COX16 mRNA CTD PMID:17211630 NCBI chr14:70,325,081...70,359,683
Ensembl chr14:70,325,081...70,416,984
JBrowse link
G COX5B cytochrome c oxidase subunit 5B decreases expression ISO cupric chloride results in decreased expression of COX5B protein CTD PMID:29617964 NCBI chr 2:97,646,062...97,648,383
Ensembl chr 2:97,646,062...97,648,383
JBrowse link
G COX6A1 cytochrome c oxidase subunit 6A1 increases expression ISO cupric chloride results in increased expression of COX6A1 protein CTD PMID:29617964 NCBI chr12:120,438,113...120,440,730
Ensembl chr12:120,438,090...120,440,737
JBrowse link
G CP ceruloplasmin increases expression EXP cupric chloride results in increased expression of CP mRNA CTD PMID:15741220 NCBI chr 3:149,162,410...149,222,008
Ensembl chr 3:149,162,410...149,221,829
JBrowse link
G CPLX2 complexin 2 decreases expression ISO cupric chloride results in decreased expression of CPLX2 protein CTD PMID:29617964 NCBI chr 5:175,796,533...175,884,021
Ensembl chr 5:175,796,310...175,884,021
JBrowse link
G CRYAB crystallin alpha B increases expression EXP cupric chloride results in increased expression of CRYAB mRNA CTD PMID:17211630 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722
JBrowse link
G CSTB cystatin B affects binding EXP CSTB protein binds to cupric chloride CTD PMID:16939620 NCBI chr21:43,773,950...43,776,308
Ensembl chr21:43,772,511...43,776,330
Ensembl chr21:43,772,511...43,776,330
Ensembl chr21:43,772,511...43,776,330
JBrowse link
G CTSB cathepsin B multiple interactions
decreases expression
ISO PP242 inhibits the reaction [cupric chloride results in decreased expression of CTSB mRNA]; PP242 inhibits the reaction [cupric chloride results in decreased expression of CTSB protein]
cupric chloride results in decreased expression of CTSB mRNA; cupric chloride results in decreased expression of CTSB protein
CTD PMID:32512069 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,448
Ensembl chr 8:11,842,524...11,869,448
JBrowse link
G CTSD cathepsin D decreases expression
multiple interactions
ISO cupric chloride results in decreased expression of CTSD mRNA
PP242 inhibits the reaction [cupric chloride results in decreased expression of CTSD mRNA]
CTD PMID:32512069 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,755...1,764,573
Ensembl chr11:1,752,755...1,764,573
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases secretion
increases expression
EXP cupric chloride results in increased secretion of CXCL8 protein
cupric chloride results in increased expression of CXCL8 mRNA; cupric chloride results in increased expression of CXCL8 protein
CTD PMID:12865660 PMID:17211630 PMID:29355601 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,541...73,743,716
JBrowse link
G CYCS cytochrome c, somatic multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which affects the localization of CYCS protein CTD PMID:20920558 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
JBrowse link
G CYFIP2 cytoplasmic FMR1 interacting protein 2 decreases expression EXP cupric chloride results in decreased expression of CYFIP2 mRNA CTD PMID:17211630 NCBI chr 5:157,266,091...157,395,594
Ensembl chr 5:157,266,079...157,395,595
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases stability
multiple interactions
ISO cupric chloride results in increased stability of CYP1A1 mRNA; cupric chloride results in increased stability of CYP1A1 protein
[1,10-phenanthroline co-treated with cupric chloride] inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; [1,10-phenanthroline co-treated with cupric chloride] inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]
CTD PMID:19896525 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 increases expression ISO cupric chloride results in increased expression of CYP27A1 mRNA CTD PMID:17211630 NCBI chr 2:218,781,733...218,815,293
Ensembl chr 2:218,781,749...218,815,293
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 multiple interactions EXP [CYP2B6 protein co-treated with cupric chloride co-treated with NADP] results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; [CYP2B6 protein co-treated with cupric chloride co-treated with NADP] results in increased metabolism of N'-nitrosonornicotine CTD PMID:32672941 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 increases expression ISO cupric chloride results in increased expression of CYP2C38 mRNA CTD PMID:17211630 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions
increases expression
ISO
EXP
pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of DDIT3 mRNA]
cupric chloride results in increased expression of DDIT3 mRNA
CTD PMID:17211630 PMID:20920558 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 increases expression EXP cupric chloride results in increased expression of DKK1 mRNA CTD PMID:17211630 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042
JBrowse link
G DMD dystrophin increases expression EXP cupric chloride results in increased expression of DMD mRNA CTD PMID:17211630 NCBI chr  X:31,119,219...33,339,460
Ensembl chr  X:31,097,677...33,339,441
Ensembl chr  X:31,097,677...33,339,441
JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 increases expression EXP cupric chloride results in increased expression of DNAJB1 mRNA CTD PMID:17211630 NCBI chr19:14,514,769...14,530,597
Ensembl chr19:14,514,769...14,529,770
Ensembl chr19:14,514,769...14,529,770
JBrowse link
G DPYSL2 dihydropyrimidinase like 2 increases expression ISO cupric chloride results in increased expression of DPYSL2 protein CTD PMID:29617964 NCBI chr 8:26,514,031...26,658,175
Ensembl chr 8:26,514,031...26,658,178
JBrowse link
G DPYSL5 dihydropyrimidinase like 5 increases expression ISO cupric chloride results in increased expression of DPYSL5 protein CTD PMID:29617964 NCBI chr 2:26,847,995...26,950,351
Ensembl chr 2:26,847,747...26,950,351
JBrowse link
G DUSP1 dual specificity phosphatase 1 increases expression EXP cupric chloride results in increased expression of DUSP1 mRNA CTD PMID:17211630 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
JBrowse link
G EGR1 early growth response 1 affects expression EXP cupric chloride affects the expression of EGR1 mRNA CTD PMID:17211630 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G ELAC2 elaC ribonuclease Z 2 affects expression EXP cupric chloride affects the expression of ELAC2 mRNA CTD PMID:17211630 NCBI chr17:12,991,612...13,018,027
Ensembl chr17:12,991,612...13,018,065
JBrowse link
G ELOVL1 ELOVL fatty acid elongase 1 increases expression EXP cupric chloride results in increased expression of ELOVL1 mRNA CTD PMID:17211630 NCBI chr 1:43,363,401...43,368,011
Ensembl chr 1:43,363,398...43,368,074
JBrowse link
G EML4 EMAP like 4 decreases expression EXP cupric chloride results in decreased expression of EML4 mRNA CTD PMID:17211630 NCBI chr 2:42,169,353...42,332,548
Ensembl chr 2:42,169,353...42,332,548
JBrowse link
G ENAM enamelin affects expression EXP cupric chloride affects the expression of ENAM mRNA CTD PMID:17211630 NCBI chr 4:70,627,471...70,646,824
Ensembl chr 4:70,628,744...70,646,824
JBrowse link
G ENDOG endonuclease G increases expression ISO cupric chloride results in increased expression of ENDOG protein CTD PMID:22239859 NCBI chr 9:128,818,402...128,822,676
Ensembl chr 9:128,818,500...128,822,676
JBrowse link
G ESR1 estrogen receptor 1 multiple interactions
increases activity
affects response to substance
decreases expression
EXP cupric chloride inhibits the reaction [Estradiol binds to ESR1 protein]; cupric chloride promotes the reaction [Estradiol results in decreased expression of ESR1 mRNA]; cupric chloride promotes the reaction [Estradiol results in decreased expression of ESR1 protein]; Estradiol promotes the reaction [cupric chloride results in decreased expression of ESR1 mRNA]; Estradiol promotes the reaction [cupric chloride results in decreased expression of ESR1 protein]
cupric chloride results in increased activity of ESR1 protein
ESR1 protein affects the susceptibility to cupric chloride
cupric chloride results in decreased expression of ESR1 mRNA; cupric chloride results in decreased expression of ESR1 protein
CTD PMID:12746304 PMID:17716812 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G F2 coagulation factor II, thrombin increases expression ISO cupric chloride results in increased expression of F2 mRNA CTD PMID:17211630 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G FAM219A family with sequence similarity 219 member A increases expression EXP cupric chloride results in increased expression of FAM219A mRNA CTD PMID:17211630 NCBI chr 9:34,398,184...34,458,570
Ensembl chr 9:34,398,184...34,458,570
JBrowse link
G FAM89B family with sequence similarity 89 member B increases expression EXP cupric chloride results in increased expression of FAM89B mRNA CTD PMID:17211630 NCBI chr11:65,572,538...65,574,190
Ensembl chr11:65,572,349...65,574,198
JBrowse link
G FETUB fetuin B increases expression ISO cupric chloride results in increased expression of FETUB mRNA CTD PMID:17211630 NCBI chr 3:186,635,969...186,653,141
Ensembl chr 3:186,635,969...186,653,141
JBrowse link
G FGF1 fibroblast growth factor 1 multiple interactions EXP [amlexanox binds to FGF1 protein] inhibits the reaction [cupric chloride results in increased oxidation of FGF1 protein] CTD PMID:16300395 NCBI chr 5:142,592,178...142,698,070
Ensembl chr 5:142,592,178...142,698,070
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 affects expression EXP cupric chloride affects the expression of FGFR1 mRNA CTD PMID:17211630 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link
G FHL3 four and a half LIM domains 3 increases expression EXP cupric chloride results in increased expression of FHL3 mRNA CTD PMID:17211630 NCBI chr 1:37,996,765...38,005,691
Ensembl chr 1:37,996,770...38,005,606
JBrowse link
G FKBP4 FKBP prolyl isomerase 4 increases expression EXP cupric chloride results in increased expression of FKBP4 mRNA CTD PMID:17211630 NCBI chr12:2,794,970...2,805,423
Ensembl chr12:2,794,970...2,805,423
JBrowse link
G FMO5 flavin containing dimethylaniline monoxygenase 5 decreases expression EXP cupric chloride results in decreased expression of FMO5 mRNA CTD PMID:17211630 NCBI chr 1:147,183,963...147,225,798
Ensembl chr 1:147,175,351...147,243,050
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP cupric chloride results in increased expression of FOS mRNA CTD PMID:17211630 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FTH1P5 ferritin heavy chain 1 pseudogene 5 increases expression EXP cupric chloride results in increased expression of FTH1P5 mRNA CTD PMID:17211630 NCBI chr 6:50,912,550...50,913,462
Ensembl chr 6:50,912,712...50,913,256
JBrowse link
G FUBP1 far upstream element binding protein 1 increases expression ISO cupric chloride results in increased expression of FUBP1 protein CTD PMID:29617964 NCBI chr 1:77,944,055...77,979,435
Ensembl chr 1:77,944,055...77,979,110
JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 affects expression EXP cupric chloride affects the expression of FXYD2 mRNA CTD PMID:17211630 NCBI chr11:117,820,057...117,828,089
Ensembl chr11:117,800,844...117,828,698
JBrowse link
G GABARAPL3 GABA type A receptor associated protein like 3 pseudogene increases expression EXP cupric chloride results in increased expression of GABARAPL3 mRNA CTD PMID:17211630 NCBI chr15:90,346,527...90,349,447
Ensembl chr15:90,348,844...90,349,197
JBrowse link
G GABRE gamma-aminobutyric acid type A receptor subunit epsilon increases expression EXP cupric chloride results in increased expression of GABRE mRNA CTD PMID:17211630 NCBI chr  X:151,953,124...151,974,692
Ensembl chr  X:151,953,124...151,974,680
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression EXP cupric chloride results in increased expression of GADD45A mRNA CTD PMID:17211630 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit increases expression EXP cupric chloride results in increased expression of GCLC mRNA CTD PMID:17211630 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit increases expression EXP cupric chloride results in increased expression of GCLM mRNA CTD PMID:17211630 PMID:24343273 NCBI chr 1:93,885,199...93,910,370
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G GDI1 GDP dissociation inhibitor 1 increases expression ISO cupric chloride results in increased expression of GDI1 protein CTD PMID:29617964 NCBI chr  X:154,437,154...154,443,467
Ensembl chr  X:154,436,913...154,443,467
JBrowse link
G GLA galactosidase alpha increases expression EXP cupric chloride results in increased expression of GLA mRNA CTD PMID:17211630 NCBI chr  X:101,397,803...101,407,925
Ensembl chr  X:101,393,273...101,408,012
Ensembl chr  X:101,393,273...101,408,012
JBrowse link
G GLUD1 glutamate dehydrogenase 1 decreases expression EXP cupric chloride results in decreased expression of GLUD1 mRNA CTD PMID:17211630 NCBI chr10:87,050,202...87,094,843
Ensembl chr10:87,050,202...87,094,843
JBrowse link
G GTPBP2 GTP binding protein 2 affects expression EXP cupric chloride affects the expression of GTPBP2 mRNA CTD PMID:17211630 NCBI chr 6:43,620,492...43,631,309
Ensembl chr 6:43,605,316...43,629,264
JBrowse link
G GTPBP6 GTP binding protein 6 (putative) increases expression EXP cupric chloride results in increased expression of GTPBP6 mRNA CTD PMID:17211630 NCBI chr  X:303,352...318,819
NCBI chr  Y:303,352...318,819
Ensembl chr  X:304,529...318,819
JBrowse link
G GYPE glycophorin E (MNS blood group) affects expression EXP cupric chloride affects the expression of GYPE mRNA CTD PMID:17211630 NCBI chr 4:143,870,864...143,912,131
Ensembl chr 4:143,870,864...143,905,563
JBrowse link
G HAMP hepcidin antimicrobial peptide increases expression ISO cupric chloride results in increased expression of HAMP mRNA CTD PMID:17211630 NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143
JBrowse link
G HEXA hexosaminidase subunit alpha decreases expression
multiple interactions
ISO cupric chloride results in decreased expression of HEXA mRNA
PP242 inhibits the reaction [cupric chloride results in decreased expression of HEXA mRNA]
CTD PMID:32512069 NCBI chr15:72,340,924...72,376,014
Ensembl chr15:72,340,919...72,376,476
Ensembl chr15:72,340,919...72,376,476
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions
increases stability
affects localization
decreases hydroxylation
EXP Ascorbic Acid inhibits the reaction [cupric chloride results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [cupric chloride results in increased stability of HIF1A protein]; cupric chloride results in decreased hydroxylation of and results in decreased degradation of HIF1A protein
cupric chloride affects the localization of HIF1A protein
CTD PMID:15741220 PMID:19074761 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HK1 hexokinase 1 decreases activity ISO cupric chloride results in decreased activity of HK1 protein CTD PMID:22349057 NCBI chr10:69,269,991...69,401,882
Ensembl chr10:69,269,984...69,401,884
JBrowse link
G HMOX1 heme oxygenase 1 increases expression EXP cupric chloride results in increased expression of HMOX1 mRNA; cupric chloride results in increased expression of HMOX1 protein CTD PMID:17211630 PMID:21242307 PMID:24343273 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,207
Ensembl chr22:35,380,361...35,394,207
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 increases expression EXP cupric chloride results in increased expression of HSP90AA1 mRNA CTD PMID:17211630 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,738...102,139,699
Ensembl chr14:102,080,738...102,139,699
JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA] CTD PMID:20920558 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,645
Ensembl chr12:103,930,107...103,953,645
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A affects expression EXP cupric chloride affects the expression of HSPA1A mRNA CTD PMID:20945374 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B increases expression EXP cupric chloride results in increased expression of HSPA1B mRNA CTD PMID:17211630 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA] CTD PMID:20920558 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,343
JBrowse link
G HSPA6 heat shock protein family A (Hsp70) member 6 increases expression EXP cupric chloride results in increased expression of HSPA6 mRNA CTD PMID:17211630 NCBI chr 1:161,524,540...161,526,894
Ensembl chr 1:161,524,540...161,526,894
JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 decreases expression ISO cupric chloride results in decreased expression of HSPA9 protein CTD PMID:29617964 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,416
Ensembl chr 5:138,553,756...138,575,416
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 increases expression EXP cupric chloride results in increased expression of HSPB1 mRNA CTD PMID:17211630 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295
JBrowse link
G ID2 inhibitor of DNA binding 2 affects expression EXP cupric chloride affects the expression of ID2 mRNA CTD PMID:17211630 NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461
JBrowse link
G IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha decreases expression ISO cupric chloride results in decreased expression of IDH3A protein CTD PMID:29617964 NCBI chr15:78,149,362...78,171,945
Ensembl chr15:78,131,498...78,171,945
JBrowse link
G IER2 immediate early response 2 increases expression EXP cupric chloride results in increased expression of IER2 mRNA CTD PMID:17211630 NCBI chr19:13,150,411...13,154,911
Ensembl chr19:13,150,411...13,154,911
JBrowse link
G IER5 immediate early response 5 increases expression EXP cupric chloride results in increased expression of IER5 mRNA CTD PMID:17211630 NCBI chr 1:181,088,700...181,092,900
Ensembl chr 1:181,088,700...181,092,900
JBrowse link
G IFIT1 interferon induced protein with tetratricopeptide repeats 1 increases expression EXP cupric chloride results in increased expression of IFIT1 mRNA CTD PMID:17211630 NCBI chr10:89,392,623...89,406,487
Ensembl chr10:89,392,546...89,406,487
JBrowse link
G IFNG interferon gamma multiple interactions ISO cupric chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]] CTD PMID:8975779 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IGF1 insulin like growth factor 1 increases expression ISO cupric chloride results in increased expression of IGF1 mRNA CTD PMID:17211630 NCBI chr12:102,395,860...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IGHMBP2 immunoglobulin mu DNA binding protein 2 increases expression EXP cupric chloride results in increased expression of IGHMBP2 mRNA CTD PMID:17211630 NCBI chr11:68,903,855...68,940,601
Ensembl chr11:68,903,863...68,940,602
Ensembl chr11:68,903,863...68,940,602
Ensembl chr11:68,903,863...68,940,602
JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma increases expression EXP cupric chloride results in increased expression of IKBKG mRNA CTD PMID:17211630 NCBI chr  X:154,541,238...154,565,046
Ensembl chr  X:154,541,199...154,565,046
JBrowse link
G IL1A interleukin 1 alpha increases secretion EXP cupric chloride results in increased secretion of IL1A protein CTD PMID:22954531 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL6 interleukin 6 multiple interactions EXP cupric chloride inhibits the reaction [TNF protein results in increased secretion of IL6 protein] CTD PMID:23285694 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IMMT inner membrane mitochondrial protein decreases expression ISO cupric chloride results in decreased expression of IMMT protein CTD PMID:29617964 NCBI chr 2:86,143,932...86,195,463
Ensembl chr 2:86,143,932...86,195,770
Ensembl chr 2:86,143,932...86,195,770
JBrowse link
G IRS2 insulin receptor substrate 2 increases expression EXP cupric chloride results in increased expression of IRS2 mRNA CTD PMID:17211630 NCBI chr13:109,752,695...109,786,583
Ensembl chr13:109,752,695...109,786,583
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
EXP
ISO
cupric chloride results in increased expression of JUN mRNA
[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein]
[Disulfiram co-treated with cupric chloride co-treated with Doxorubicin] results in increased expression of and results in increased phosphorylation of JUN protein
CTD PMID:17211630 PMID:21911303 PMID:30768131 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
JBrowse link
G KDM2A lysine demethylase 2A increases expression EXP cupric chloride results in increased expression of KDM2A mRNA CTD PMID:17211630 NCBI chr11:67,119,263...67,258,082
Ensembl chr11:67,119,263...67,258,082
JBrowse link
G KDM3A lysine demethylase 3A increases expression EXP cupric chloride results in increased expression of KDM3A mRNA CTD PMID:17211630 NCBI chr 2:86,440,647...86,492,716
Ensembl chr 2:86,440,647...86,492,716
JBrowse link
G KIF5A kinesin family member 5A decreases activity
multiple interactions
EXP cupric chloride results in decreased activity of KIF5A protein
Cysteine inhibits the reaction [cupric chloride results in decreased activity of KIF5A protein]; Dithiothreitol inhibits the reaction [cupric chloride results in decreased activity of KIF5A protein]; Egtazic Acid inhibits the reaction [cupric chloride results in decreased activity of KIF5A protein]
CTD PMID:24853401 NCBI chr12:57,550,039...57,586,633
Ensembl chr12:57,546,026...57,586,633
Ensembl chr12:57,546,026...57,586,633
JBrowse link
G KLF6 Kruppel like factor 6 affects expression EXP cupric chloride affects the expression of KLF6 mRNA CTD PMID:17211630 NCBI chr10:3,775,996...3,785,209
Ensembl chr10:3,775,996...3,785,281
JBrowse link
G KNG1 kininogen 1 increases expression ISO cupric chloride results in increased expression of KNG1 mRNA; cupric chloride results in increased expression of KNG2 mRNA CTD PMID:17211630 NCBI chr 3:186,717,359...186,744,410
Ensembl chr 3:186,717,348...186,744,410
JBrowse link
G LAMP1 lysosomal associated membrane protein 1 multiple interactions
decreases expression
ISO PP242 inhibits the reaction [cupric chloride results in decreased expression of LAMP1 mRNA]; PP242 inhibits the reaction [cupric chloride results in decreased expression of LAMP1 protein]
cupric chloride results in decreased expression of LAMP1 mRNA; cupric chloride results in decreased expression of LAMP1 protein
CTD PMID:32512069 NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,239...113,323,672
JBrowse link
G LAMP2 lysosomal associated membrane protein 2 multiple interactions
decreases expression
ISO PP242 inhibits the reaction [cupric chloride results in decreased expression of LAMP2 mRNA] CTD PMID:32512069 NCBI chr  X:120,426,148...120,469,349
Ensembl chr  X:120,426,148...120,469,365
Ensembl chr  X:120,426,148...120,469,365
JBrowse link
G LCAT lecithin-cholesterol acyltransferase increases expression ISO cupric chloride results in increased expression of LCAT mRNA CTD PMID:17211630 NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131
JBrowse link
G LOX lysyl oxidase increases activity
multiple interactions
ISO
EXP
cupric chloride results in increased activity of LOX protein
Aminopropionitrile inhibits the reaction [cupric chloride results in increased activity of LOX protein]
CTD PMID:22367676 PMID:25044713 NCBI chr 5:122,063,195...122,078,259
Ensembl chr 5:122,063,195...122,078,360
Ensembl chr 5:122,063,195...122,078,360
JBrowse link
G LY6E lymphocyte antigen 6 family member E increases expression ISO cupric chloride results in increased expression of LY6E mRNA CTD PMID:17211630 NCBI chr 8:143,018,529...143,022,409
Ensembl chr 8:143,017,982...143,023,832
JBrowse link
G MAD2L1BP MAD2L1 binding protein increases expression EXP cupric chloride results in increased expression of MAD2L1BP mRNA CTD PMID:17211630 NCBI chr 6:43,629,540...43,640,941
Ensembl chr 6:43,629,540...43,640,941
Ensembl chr 6:43,629,540...43,640,941
JBrowse link
G MAFG MAF bZIP transcription factor G increases expression EXP cupric chloride results in increased expression of MAFG mRNA CTD PMID:17211630 NCBI chr17:81,918,270...81,927,735
Ensembl chr17:81,918,270...81,927,735
JBrowse link
G MAGEA2 MAGE family member A2 increases expression EXP cupric chloride results in increased expression of MAGEA2 mRNA CTD PMID:17211630 NCBI chr  X:152,749,863...152,753,884
Ensembl chr  X:152,749,863...152,753,884
JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta increases expression
multiple interactions
EXP
ISO
cupric chloride results in increased expression of MAP1LC3B mRNA
cupric chloride results in increased expression of MAP1LC3B protein modified form
Acetylcysteine inhibits the reaction [cupric chloride results in increased expression of MAP1LC3B protein modified form]; cupric chloride inhibits the reaction [3-methyladenine results in decreased expression of MAP1LC3B protein modified form]; PP242 promotes the reaction [cupric chloride results in increased expression of MAP1LC3B protein modified form]
CTD PMID:17211630 PMID:32512069 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK1 protein CTD PMID:20920558 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,754,500...21,867,680
Ensembl chr22:21,754,500...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK3 protein CTD PMID:20920558 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions ISO [Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]
[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein]
CTD PMID:11239917 PMID:20920558 PMID:30768131 NCBI chr10:48,306,673...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
G MCM2 minichromosome maintenance complex component 2 multiple interactions EXP cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM2 mRNA] CTD PMID:19789329 NCBI chr 3:127,598,411...127,622,436
Ensembl chr 3:127,598,410...127,622,436
JBrowse link
G MCM5 minichromosome maintenance complex component 5 multiple interactions EXP cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM5 mRNA] CTD PMID:19789329 NCBI chr22:35,400,133...35,454,942
Ensembl chr22:35,400,134...35,425,431
JBrowse link
G MDH2 malate dehydrogenase 2 increases expression ISO cupric chloride results in increased expression of MDH2 protein CTD PMID:29617964 NCBI chr 7:76,048,106...76,067,508
Ensembl chr 7:76,048,051...76,067,508
JBrowse link
G MED15 mediator complex subunit 15 increases expression EXP cupric chloride results in increased expression of MED15 mRNA CTD PMID:17211630 NCBI chr22:20,507,582...20,587,621
Ensembl chr22:20,495,913...20,587,632
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase multiple interactions EXP [Disulfiram co-treated with cupric chloride] affects the expression of and affects the activity of MGMT protein CTD PMID:24193513 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983
JBrowse link
G MLLT11 MLLT11 transcription factor 7 cofactor increases expression EXP cupric chloride results in increased expression of MLLT11 mRNA CTD PMID:17211630 NCBI chr 1:151,060,397...151,069,544
Ensembl chr 1:151,060,397...151,069,544
Ensembl chr 1:151,060,397...151,069,544
JBrowse link
G MMP2 matrix metallopeptidase 2 increases secretion ISO cupric chloride results in increased secretion of MMP2 protein CTD PMID:11045606 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MRPL4 mitochondrial ribosomal protein L4 increases expression EXP cupric chloride results in increased expression of MRPL4 mRNA CTD PMID:17211630 NCBI chr19:10,251,951...10,260,055
Ensembl chr19:10,251,901...10,260,055
JBrowse link
G MSRB1 methionine sulfoxide reductase B1 increases expression EXP cupric chloride results in increased expression of MSRB1 mRNA CTD PMID:17211630 NCBI chr16:1,938,229...1,943,199
Ensembl chr16:1,938,210...1,943,326
Ensembl chr16:1,938,210...1,943,326
JBrowse link
G MT1A metallothionein 1A increases expression EXP
ISO
cupric chloride results in increased expression of MT1A mRNA CTD PMID:17211630 PMID:23174565 NCBI chr16:56,638,666...56,640,087
Ensembl chr16:56,638,666...56,640,087
JBrowse link
G MT1B metallothionein 1B multiple interactions
increases expression
EXP cupric chloride promotes the reaction [Disulfiram results in increased expression of MT1B mRNA]
cupric chloride results in increased expression of MT1B mRNA
CTD PMID:17211630 PMID:19789329 NCBI chr16:56,651,886...56,653,204
Ensembl chr16:56,651,886...56,653,204
JBrowse link
G MT1E metallothionein 1E increases expression EXP cupric chloride results in increased expression of MT1E mRNA CTD PMID:17211630 NCBI chr16:56,625,781...56,627,112
Ensembl chr16:56,625,475...56,627,112
JBrowse link
G MT1F metallothionein 1F multiple interactions
increases expression
decreases expression
EXP cupric chloride promotes the reaction [Disulfiram results in increased expression of MT1F mRNA]
cupric chloride results in increased expression of MT1F mRNA
cupric chloride deficiency results in decreased expression of MT1F mRNA
CTD PMID:17211630 PMID:19789329 NCBI chr16:56,657,959...56,659,303
Ensembl chr16:56,657,731...56,660,698
JBrowse link
G MT1G metallothionein 1G multiple interactions
increases expression
EXP cupric chloride promotes the reaction [Disulfiram results in increased expression of MT1G mRNA]
cupric chloride results in increased expression of MT1G mRNA
CTD PMID:19789329 PMID:32870474 NCBI chr16:56,666,730...56,668,065
Ensembl chr16:56,666,731...56,668,065
Ensembl chr16:56,666,731...56,668,065
JBrowse link
G MT1L metallothionein 1L, pseudogene increases expression EXP cupric chloride results in increased expression of MT1L mRNA CTD PMID:17211630 NCBI chr16:56,617,461...56,618,818
Ensembl chr16:56,617,476...56,618,818
JBrowse link
G MT1X metallothionein 1X multiple interactions
increases expression
decreases expression
EXP cupric chloride promotes the reaction [Disulfiram results in increased expression of MT1X mRNA]
cupric chloride results in increased expression of MT1X mRNA
cupric chloride deficiency results in decreased expression of MT1X mRNA
CTD PMID:17211630 PMID:19789329 PMID:24343273 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196
JBrowse link
G MT2A metallothionein 2A multiple interactions
increases expression
affects expression
EXP
ISO
cupric chloride promotes the reaction [Disulfiram results in increased expression of MT2A mRNA]
cupric chloride results in increased expression of MT2A mRNA
cupric chloride affects the expression of MT2A mRNA
CTD PMID:17211630 PMID:17409708 PMID:19789329 PMID:20945374 PMID:23174565 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
JBrowse link
G MTOR mechanistic target of rapamycin kinase increases phosphorylation ISO cupric chloride results in increased phosphorylation of MTOR protein CTD PMID:32512069 NCBI chr 1:11,106,535...11,273,497
Ensembl chr 1:11,106,535...11,262,551
JBrowse link
G NCF2 neutrophil cytosolic factor 2 increases expression EXP cupric chloride results in increased expression of NCF2 mRNA CTD PMID:17211630 NCBI chr 1:183,555,562...183,590,914
Ensembl chr 1:183,555,563...183,590,876
Ensembl chr 1:183,555,563...183,590,876
JBrowse link
G NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 decreases expression ISO cupric chloride results in decreased expression of NDUFS1 protein CTD PMID:29617964 NCBI chr 2:206,114,817...206,159,444
Ensembl chr 2:206,114,817...206,159,509
JBrowse link
G NDUFS4 NADH:ubiquinone oxidoreductase subunit S4 decreases expression ISO cupric chloride results in decreased expression of NDUFS4 protein CTD PMID:29617964 NCBI chr 5:53,560,610...53,683,338
Ensembl chr 5:53,560,633...53,683,338
JBrowse link
G NDUFV1 NADH:ubiquinone oxidoreductase core subunit V1 decreases expression ISO cupric chloride results in decreased expression of NDUFV1 protein CTD PMID:29617964 NCBI chr11:67,606,936...67,612,554
Ensembl chr11:67,605,653...67,612,554
JBrowse link
G NDUFV3 NADH:ubiquinone oxidoreductase subunit V3 decreases expression ISO cupric chloride results in decreased expression of NDUFV3 protein CTD PMID:29617964 NCBI chr21:42,893,271...42,913,299
Ensembl chr21:42,879,644...42,913,304
JBrowse link
G NEFL neurofilament light chain decreases expression ISO cupric chloride results in decreased expression of NEFL protein CTD PMID:29617964 NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,957,110
Ensembl chr 8:24,950,955...24,957,110
JBrowse link
G NFIX nuclear factor I X decreases expression EXP cupric chloride results in decreased expression of NFIX mRNA CTD PMID:17211630 NCBI chr19:12,995,475...13,098,796
Ensembl chr19:12,995,608...13,098,796
Ensembl chr19:12,995,608...13,098,796
JBrowse link
G NFKBIA NFKB inhibitor alpha decreases expression ISO cupric chloride results in decreased expression of NFKBIA protein CTD PMID:24530511 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,511...35,404,749
Ensembl chr14:35,401,511...35,404,749
JBrowse link
G NME1 NME/NM23 nucleoside diphosphate kinase 1 increases expression ISO cupric chloride results in increased expression of NME1 protein CTD PMID:29617964 NCBI chr17:51,153,559...51,162,168
Ensembl chr17:51,153,559...51,162,428
Ensembl chr17:51,153,559...51,162,428
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
increases expression
ISO cupric chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]]
cupric chloride results in increased expression of NOS2 protein
CTD PMID:8975779 PMID:23313662 PMID:24170445 PMID:24530511 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NUP107 nucleoporin 107 increases expression EXP cupric chloride results in increased expression of NUP107 mRNA CTD PMID:17211630 NCBI chr12:68,686,971...68,745,809
Ensembl chr12:68,686,951...68,745,809
JBrowse link
G P2RX2 purinergic receptor P2X 2 multiple interactions ISO cupric chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein] CTD PMID:16190872 NCBI chr12:132,618,776...132,623,736
Ensembl chr12:132,618,776...132,622,388
JBrowse link
G P3H4 prolyl 3-hydroxylase family member 4 (inactive) affects expression EXP cupric chloride affects the expression of P3H4 mRNA CTD PMID:17211630 NCBI chr17:41,801,952...41,812,710
Ensembl chr17:41,801,947...41,812,604
JBrowse link
G PALLD palladin, cytoskeletal associated protein increases expression EXP cupric chloride results in increased expression of PALLD mRNA CTD PMID:17211630 NCBI chr 4:168,497,039...168,928,441
Ensembl chr 4:168,497,052...168,928,457
JBrowse link
G PAQR8 progestin and adipoQ receptor family member 8 decreases expression EXP cupric chloride results in decreased expression of PAQR8 mRNA CTD PMID:17211630 NCBI chr 6:52,362,151...52,407,777
Ensembl chr 6:52,361,421...52,407,777
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions
increases expression
EXP
ISO
[Disulfiram co-treated with cupric chloride] results in increased cleavage of PARP1 protein; [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased cleavage of PARP1 protein
cupric chloride results in increased expression of PARP1 protein
CTD PMID:19789329 PMID:21035945 PMID:23313662 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,691...226,408,093
JBrowse link
G PCM1 pericentriolar material 1 decreases expression EXP cupric chloride results in decreased expression of PCM1 mRNA CTD PMID:17211630 NCBI chr 8:17,922,784...18,029,948
Ensembl chr 8:17,922,840...18,027,975
Ensembl chr 8:17,922,840...18,027,975
JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 decreases expression ISO cupric chloride results in decreased expression of PDIA3 protein CTD PMID:29617964 NCBI chr15:43,746,438...43,773,278
Ensembl chr15:43,746,410...43,773,278
JBrowse link
G PDZK1 PDZ domain containing 1 decreases expression EXP cupric chloride results in decreased expression of PDZK1 mRNA CTD PMID:17211630 NCBI chr 1:145,670,852...145,708,201
Ensembl chr 1:145,670,852...145,708,148
JBrowse link
G PEG10 paternally expressed 10 decreases expression EXP cupric chloride results in decreased expression of PEG10 mRNA CTD PMID:17211630 NCBI chr 7:94,656,325...94,669,695
Ensembl chr 7:94,656,325...94,669,695
JBrowse link
G PGAM1 phosphoglycerate mutase 1 increases expression ISO cupric chloride results in increased expression of PGAM1 protein CTD PMID:29617964 NCBI chr10:97,426,191...97,433,444
Ensembl chr10:97,426,191...97,433,444
JBrowse link
G PGR progesterone receptor multiple interactions
increases expression
EXP cupric chloride promotes the reaction [Estradiol results in increased expression of PGR mRNA]; cupric chloride promotes the reaction [Estradiol results in increased expression of PGR protein]; Estradiol promotes the reaction [cupric chloride results in increased expression of PGR mRNA]; Estradiol promotes the reaction [cupric chloride results in increased expression of PGR protein]; fulvestrant inhibits the reaction [cupric chloride results in increased expression of PGR mRNA]; fulvestrant inhibits the reaction [cupric chloride results in increased expression of PGR protein]
cupric chloride results in increased expression of PGR mRNA; cupric chloride results in increased expression of PGR protein
CTD PMID:12746304 NCBI chr11:101,029,624...101,130,681
Ensembl chr11:101,029,624...101,129,813
JBrowse link
G PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein decreases expression EXP cupric chloride results in decreased expression of PHYHIP mRNA CTD PMID:17211630 NCBI chr 8:22,219,703...22,232,099
Ensembl chr 8:22,219,703...22,232,101
JBrowse link
G PITPNC1 phosphatidylinositol transfer protein cytoplasmic 1 decreases expression EXP cupric chloride results in decreased expression of PITPNC1 mRNA CTD PMID:17211630 NCBI chr17:67,377,281...67,697,256
Ensembl chr17:67,377,281...67,697,261
JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression
multiple interactions
EXP cupric chloride results in increased expression of PMAIP1 mRNA
[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased expression of PMAIP1 protein
CTD PMID:20713136 PMID:21035945 NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,948...59,904,306
Ensembl chr18:59,899,948...59,904,306
JBrowse link
G POMP proteasome maturation protein increases expression EXP cupric chloride results in increased expression of POMP mRNA CTD PMID:17211630 NCBI chr13:28,659,130...28,678,959
Ensembl chr13:28,659,104...28,678,959
JBrowse link
G PRDX1 peroxiredoxin 1 increases expression EXP cupric chloride results in increased expression of PRDX1 mRNA CTD PMID:17211630 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,511,036...45,523,047
Ensembl chr 1:45,511,036...45,523,047
JBrowse link
G PRDX3 peroxiredoxin 3 decreases expression ISO cupric chloride results in decreased expression of PRDX3 protein CTD PMID:29617964 NCBI chr10:119,167,720...119,178,812
Ensembl chr10:119,167,720...119,178,812
JBrowse link
G PRNP prion protein multiple interactions
increases expression
ISO [NADP co-treated with cupric chloride] promotes the reaction [PRNP protein binds to PRNP protein]
bathocuproine sulfonate inhibits the reaction [cupric chloride results in increased expression of PRNP protein]
cupric chloride results in increased expression of PRNP mRNA; cupric chloride results in increased expression of PRNP protein
CTD PMID:16148034 PMID:16990274 NCBI chr20:4,686,456...4,701,588
Ensembl chr20:4,686,350...4,701,590
JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa multiple interactions EXP ALB protein inhibits the reaction [cupric chloride results in decreased activity of PROC protein]; aspartyl-alanyl-histidyl-lysine inhibits the reaction [cupric chloride results in decreased activity of PROC protein]; cupric chloride binds to and results in decreased activity of PROC protein CTD PMID:11820775 NCBI chr 2:127,418,143...127,429,246
Ensembl chr 2:127,418,427...127,429,246
Ensembl chr 2:127,418,427...127,429,246
JBrowse link
G PSMB2 proteasome 20S subunit beta 2 increases expression EXP cupric chloride results in increased expression of PSMB2 mRNA CTD PMID:17211630 NCBI chr 1:35,599,541...35,641,526
Ensembl chr 1:35,599,541...35,641,526
JBrowse link
G PSMB3 proteasome 20S subunit beta 3 increases expression EXP cupric chloride results in increased expression of PSMB3 mRNA CTD PMID:17211630 NCBI chr17:38,752,741...38,764,225
Ensembl chr17:38,752,741...38,764,225
JBrowse link
G PSMB7 proteasome 20S subunit beta 7 increases expression EXP cupric chloride results in increased expression of PSMB7 mRNA CTD PMID:17211630 NCBI chr 9:124,353,465...124,415,442
Ensembl chr 9:124,353,465...124,415,444
JBrowse link
G PSMC1 proteasome 26S subunit, ATPase 1 increases expression EXP cupric chloride results in increased expression of PSMC1 mRNA CTD PMID:17211630 NCBI chr14:90,256,553...90,275,429
Ensembl chr14:90,256,527...90,275,429
JBrowse link
G PSMC4 proteasome 26S subunit, ATPase 4 increases expression EXP cupric chloride results in increased expression of PSMC4 mRNA CTD PMID:17211630 NCBI chr19:39,971,150...39,981,764
Ensembl chr19:39,971,165...39,981,764
JBrowse link
G PSMD1 proteasome 26S subunit, non-ATPase 1 increases expression EXP cupric chloride results in increased expression of PSMD1 mRNA CTD PMID:17211630 NCBI chr 2:231,056,867...231,172,827
Ensembl chr 2:231,056,864...231,172,827
Ensembl chr 2:231,056,864...231,172,827
JBrowse link
G PSMD11 proteasome 26S subunit, non-ATPase 11 increases expression EXP cupric chloride results in increased expression of PSMD11 mRNA CTD PMID:17211630 NCBI chr17:32,444,510...32,483,319
Ensembl chr17:32,444,379...32,483,319
JBrowse link
G PSMD13 proteasome 26S subunit, non-ATPase 13 increases expression EXP cupric chloride results in increased expression of PSMD13 mRNA CTD PMID:17211630 NCBI chr11:236,972...252,984
Ensembl chr11:236,966...252,984
JBrowse link
G PSMD14 proteasome 26S subunit, non-ATPase 14 increases expression EXP cupric chloride results in increased expression of PSMD14 mRNA CTD PMID:17211630 NCBI chr 2:161,308,425...161,411,717
Ensembl chr 2:161,308,425...161,411,717
JBrowse link
G PSMD2 proteasome 26S subunit ubiquitin receptor, non-ATPase 2 increases expression EXP cupric chloride results in increased expression of PSMD2 mRNA CTD PMID:17211630 NCBI chr 3:184,299,241...184,309,050
Ensembl chr 3:184,299,198...184,309,050
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 increases expression ISO cupric chloride results in increased expression of PTGS2 protein CTD PMID:23313662 PMID:24170445 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,423
JBrowse link
G PTPRO protein tyrosine phosphatase receptor type O decreases expression EXP cupric chloride results in decreased expression of PTPRO mRNA CTD PMID:17211630 NCBI chr12:15,322,334...15,598,331
Ensembl chr12:15,322,508...15,598,331
Ensembl chr12:15,322,508...15,598,331
JBrowse link
G PURA purine rich element binding protein A decreases expression ISO cupric chloride results in decreased expression of PURA protein CTD PMID:29617964 NCBI chr 5:140,114,109...140,125,619
Ensembl chr 5:140,107,777...140,125,619
JBrowse link
G QKI QKI, KH domain containing RNA binding increases expression EXP cupric chloride results in increased expression of QKI mRNA CTD PMID:17211630 NCBI chr 6:163,414,486...163,578,592
Ensembl chr 6:163,414,000...163,578,592
JBrowse link
G RALGAPA1 Ral GTPase activating protein catalytic subunit alpha 1 affects expression EXP cupric chloride affects the expression of RALGAPA1 mRNA CTD PMID:17211630 NCBI chr14:35,538,356...35,809,295
Ensembl chr14:35,538,352...35,809,304
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO cupric chloride results in increased phosphorylation of and affects the localization of RELA protein CTD PMID:24530511 NCBI chr11:65,653,601...65,662,946
Ensembl chr11:65,653,597...65,663,090
JBrowse link
G RHOB ras homolog family member B decreases expression EXP cupric chloride results in decreased expression of ARHB mRNA CTD PMID:17211630 NCBI chr 2:20,447,074...20,449,440
Ensembl chr 2:20,447,074...20,449,440
JBrowse link
G RNF181 ring finger protein 181 affects expression EXP cupric chloride affects the expression of RNF181 mRNA CTD PMID:17211630 NCBI chr 2:85,593,823...85,597,708
Ensembl chr 2:85,595,725...85,597,708
JBrowse link
G RPL32 ribosomal protein L32 affects expression EXP cupric chloride affects the expression of RPL32 mRNA CTD PMID:17211630 NCBI chr 3:12,834,485...12,841,582
Ensembl chr 3:12,834,485...12,841,582
JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 increases phosphorylation ISO cupric chloride results in increased phosphorylation of RPS6KB1 protein CTD PMID:32512069 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574
JBrowse link
G RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression EXP cupric chloride results in increased expression of RRAD mRNA CTD PMID:17211630 NCBI chr16:66,921,685...66,925,535
Ensembl chr16:66,921,679...66,925,536
JBrowse link
G RYBP RING1 and YY1 binding protein affects expression EXP cupric chloride affects the expression of RYBP mRNA CTD PMID:17211630 NCBI chr 3:72,374,593...72,446,623
Ensembl chr 3:72,371,825...72,446,621
Ensembl chr 3:72,371,825...72,446,621
JBrowse link
G SBDS SBDS ribosome maturation factor increases expression EXP cupric chloride results in increased expression of SBDS mRNA CTD PMID:17211630 NCBI chr 7:66,987,680...66,995,586
Ensembl chr 7:66,987,680...66,995,587
JBrowse link
G SCO2 synthesis of cytochrome C oxidase 2 multiple interactions EXP cupric chloride promotes the reaction [Bezafibrate results in increased activity of SCO2 protein mutant form] CTD PMID:22515166 NCBI chr22:50,523,568...50,526,442
Ensembl chr22:50,523,568...50,526,461
JBrowse link
G SDF2 stromal cell derived factor 2 increases expression EXP cupric chloride results in increased expression of SDF2 mRNA CTD PMID:17211630 NCBI chr17:28,648,346...28,662,194
Ensembl chr17:28,648,346...28,662,189
JBrowse link
G SELENOK selenoprotein K increases expression EXP cupric chloride results in increased expression of SELENOK mRNA CTD PMID:17211630 NCBI chr 3:53,884,417...53,891,859
Ensembl chr 3:53,884,417...53,891,962
JBrowse link
G SELENOP selenoprotein P decreases expression EXP cupric chloride results in decreased expression of SELENOP mRNA CTD PMID:17211630 NCBI chr 5:42,799,880...42,811,892
Ensembl chr 5:42,799,880...42,887,392
JBrowse link
G SEPTIN4 septin 4 decreases expression ISO cupric chloride results in decreased expression of SEPTIN4 protein CTD PMID:29617964 NCBI chr17:58,520,255...58,544,372
Ensembl chr17:58,520,250...58,544,368
JBrowse link
G SEPTIN8 septin 8 decreases expression ISO cupric chloride results in decreased expression of SEPTIN8 protein CTD PMID:29617964 NCBI chr 5:132,750,819...132,778,216
Ensembl chr 5:132,750,819...132,807,241
JBrowse link
G SERPINF1 serpin family F member 1 increases expression ISO cupric chloride results in increased expression of SERPINF1 mRNA CTD PMID:17211630 NCBI chr17:1,762,060...1,777,565
Ensembl chr17:1,762,029...1,777,565
JBrowse link
G SHANK2 SH3 and multiple ankyrin repeat domains 2 multiple interactions ISO [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK2 protein CTD PMID:25007851 NCBI chr11:70,467,854...71,252,724
Ensembl chr11:70,467,856...71,252,577
Ensembl chr11:70,467,856...71,252,577
JBrowse link
G SHANK3 SH3 and multiple ankyrin repeat domains 3 multiple interactions ISO [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein CTD PMID:25007851 NCBI chr22:50,672,823...50,733,212
Ensembl chr22:50,674,415...50,733,298
JBrowse link
G SIRT7 sirtuin 7 increases expression EXP cupric chloride results in increased expression of SIRT7 mRNA CTD PMID:17211630 NCBI chr17:81,911,939...81,918,176
Ensembl chr17:81,911,939...81,921,323
JBrowse link
G SLC11A2 solute carrier family 11 member 2 multiple interactions EXP cupric chloride inhibits the reaction [SLC11A2 protein results in increased uptake of Iron] CTD PMID:12220667 NCBI chr12:50,952,263...51,028,886
Ensembl chr12:50,979,401...51,028,566
JBrowse link
G SLC13A3 solute carrier family 13 member 3 decreases expression EXP cupric chloride results in decreased expression of SLC13A3 mRNA CTD PMID:17211630 NCBI chr20:46,557,828...46,684,485
Ensembl chr20:46,557,823...46,684,467
JBrowse link
G SLC22A18 solute carrier family 22 member 18 increases expression ISO cupric chloride results in increased expression of SLC22A18 mRNA CTD PMID:17211630 NCBI chr11:2,899,691...2,925,246
Ensembl chr11:2,899,721...2,925,246
JBrowse link
G SLC2A1 solute carrier family 2 member 1 increases expression EXP cupric chloride results in increased expression of SLC2A1 mRNA CTD PMID:15741220 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893
Ensembl chr 1:42,925,353...42,958,893
JBrowse link
G SLC30A1 solute carrier family 30 member 1 increases expression EXP cupric chloride results in increased expression of SLC30A1 mRNA CTD PMID:24343273 NCBI chr 1:211,571,568...211,579,161
Ensembl chr 1:211,571,568...211,579,161
JBrowse link
G SLC31A1 solute carrier family 31 member 1 decreases expression
multiple interactions
ISO
EXP
cupric chloride results in decreased expression of SLC31A1 protein
SLC31A1 protein results in increased susceptibility to [cupric chloride results in increased abundance of Copper]
CTD PMID:24316150 PMID:24800945 PMID:32278528 NCBI chr 9:113,221,544...113,264,492
Ensembl chr 9:113,221,544...113,264,492
JBrowse link
G SNCA synuclein alpha affects folding EXP cupric chloride affects the folding of SNCA protein CTD PMID:11553618 NCBI chr 4:89,724,099...89,838,324
Ensembl chr 4:89,700,345...89,838,315
Ensembl chr 4:89,700,345...89,838,315
JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions
decreases expression
increases response to substance
EXP
ISO
cupric chloride promotes the reaction [COMMD1 protein binds to SOD1 protein]; Pyruvic Acid inhibits the reaction [SOD1 protein mutant form promotes the reaction [cupric chloride results in increased abundance of Peroxides]]; Pyruvic Acid inhibits the reaction [SOD1 protein mutant form results in increased susceptibility to cupric chloride]; SOD1 protein mutant form promotes the reaction [cupric chloride results in increased abundance of Peroxides]
cupric chloride results in decreased expression of SOD1 protein
CTD PMID:15812313 PMID:24691167 PMID:29617964 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,622...31,668,931
Ensembl chr21:31,659,622...31,668,931
JBrowse link
G SORBS1 sorbin and SH3 domain containing 1 decreases expression EXP cupric chloride results in decreased expression of SORBS1 mRNA CTD PMID:17211630 NCBI chr10:95,311,773...95,561,439
Ensembl chr10:95,311,771...95,561,414
JBrowse link
G SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 increases expression EXP cupric chloride results in increased expression of SPSB1 mRNA CTD PMID:17211630 NCBI chr 1:9,292,894...9,369,532
Ensembl chr 1:9,292,894...9,369,532
JBrowse link
G SQSTM1 sequestosome 1 increases expression
multiple interactions
EXP
ISO
cupric chloride results in increased expression of SQSTM1 mRNA
Acetylcysteine inhibits the reaction [cupric chloride results in increased expression of SQSTM1 protein]; PP242 inhibits the reaction [cupric chloride results in increased expression of SQSTM1 protein]
CTD PMID:17211630 PMID:23313662 PMID:32512069 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
JBrowse link
G ST6GAL1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 decreases expression EXP cupric chloride results in decreased expression of ST6GAL1 mRNA CTD PMID:17211630 NCBI chr 3:186,930,526...187,078,553
Ensembl chr 3:186,930,502...187,078,553
Ensembl chr 3:186,930,502...187,078,553
JBrowse link
G STAU1 staufen double-stranded RNA binding protein 1 decreases expression EXP cupric chloride results in decreased expression of STAU mRNA CTD PMID:17211630 NCBI chr20:49,113,339...49,219,295
Ensembl chr20:49,113,339...49,188,367
JBrowse link
G STMN1 stathmin 1 decreases expression ISO cupric chloride results in decreased expression of STMN1 protein CTD PMID:29617964 NCBI chr 1:25,884,179...25,906,880
Ensembl chr 1:25,884,181...25,906,991
JBrowse link
G SYN2 synapsin II decreases expression ISO cupric chloride results in decreased expression of SYN2 protein CTD PMID:29617964 NCBI chr 3:12,004,366...12,192,032
Ensembl chr 3:12,004,388...12,192,032
JBrowse link
G TAF7L TATA-box binding protein associated factor 7 like increases expression EXP cupric chloride results in increased expression of TAF7L mRNA CTD PMID:17211630 NCBI chr  X:101,268,257...101,293,083
Ensembl chr  X:101,268,253...101,293,057
JBrowse link
G TALDO1 transaldolase 1 increases expression EXP cupric chloride results in increased expression of TALDO1 mRNA CTD PMID:17211630 NCBI chr11:747,464...765,012
Ensembl chr11:747,415...765,012
JBrowse link
G TARDBP TAR DNA binding protein multiple interactions EXP cupric chloride inhibits the reaction [Paraquat affects the localization of TARDBP protein] CTD PMID:22879928 NCBI chr 1:11,012,654...11,030,528
Ensembl chr 1:11,012,662...11,030,528
Ensembl chr 1:11,012,662...11,030,528
Ensembl chr 1:11,012,662...11,030,528
Ensembl chr 1:11,012,662...11,030,528
JBrowse link
G TFDP2 transcription factor Dp-2 affects expression EXP cupric chloride affects the expression of TFDP2 mRNA CTD PMID:17211630 NCBI chr 3:141,944,428...142,149,544
Ensembl chr 3:141,944,428...142,149,544
JBrowse link
G TFEB transcription factor EB decreases expression
multiple interactions
ISO cupric chloride results in decreased expression of TFEB mRNA; cupric chloride results in decreased expression of TFEB protein
PP242 inhibits the reaction [cupric chloride results in decreased expression of TFEB protein]
CTD PMID:32512069 NCBI chr 6:41,683,978...41,736,223
Ensembl chr 6:41,683,978...41,736,259
JBrowse link
G TKT transketolase increases expression EXP cupric chloride results in increased expression of TKT mRNA CTD PMID:17211630 NCBI chr 3:53,224,712...53,256,052
Ensembl chr 3:53,224,712...53,256,052
JBrowse link
G TMED2 transmembrane p24 trafficking protein 2 decreases expression EXP cupric chloride results in decreased expression of TMED2 mRNA CTD PMID:17211630 NCBI chr12:123,584,552...123,598,582
Ensembl chr12:123,584,533...123,598,582
JBrowse link
G TNF tumor necrosis factor increases secretion
multiple interactions
increases expression
EXP
ISO
cupric chloride results in increased secretion of TNF protein
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [cupric chloride results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [cupric chloride results in increased secretion of TNF protein]; SC 514 inhibits the reaction [cupric chloride results in increased secretion of TNF protein]
cupric chloride inhibits the reaction [TNF protein results in increased secretion of IL6 protein]
cupric chloride results in increased expression of TNF protein
CTD PMID:22954531 PMID:23285694 PMID:23313662 PMID:24170445 PMID:24530511 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TP53 tumor protein p53 affects expression
multiple interactions
decreases expression
increases expression
ISO
EXP
cupric chloride affects the expression of TRP53 mRNA
[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; Ethanol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; neocuproine inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; Thiourea inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]
cupric chloride results in decreased expression of TRP53 protein
cupric chloride results in increased expression of TRP53 protein
CTD PMID:23313662 PMID:24170445 PMID:29803612 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TP73 tumor protein p73 affects expression
increases expression
ISO cupric chloride affects the expression of TRP73 protein
cupric chloride results in increased expression of TRP73 protein
CTD PMID:23313662 PMID:24170445 NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201
JBrowse link
G TPM1 tropomyosin 1 increases expression ISO cupric chloride results in increased expression of TPM1 protein CTD PMID:29617964 NCBI chr15:63,042,698...63,071,915
Ensembl chr15:63,042,632...63,071,915
JBrowse link
G TPPP tubulin polymerization promoting protein increases expression ISO cupric chloride results in increased expression of TPPP protein CTD PMID:29617964 NCBI chr 5:659,862...700,727
Ensembl chr 5:659,862...693,352
JBrowse link
G TRAF5 TNF receptor associated factor 5 increases expression EXP cupric chloride results in increased expression of TRAF5 mRNA CTD PMID:17211630 NCBI chr 1:211,326,594...211,374,946
Ensembl chr 1:211,326,615...211,374,946
JBrowse link
G TRIB3 tribbles pseudokinase 3 increases expression EXP cupric chloride results in increased expression of TRIB3 mRNA CTD PMID:17211630 NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559
JBrowse link
G TSC22D3 TSC22 domain family member 3 multiple interactions ISO [cupric chloride results in increased abundance of Copper] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:107,713,221...107,777,329
Ensembl chr  X:107,713,221...107,777,342
JBrowse link
G TXN thioredoxin increases expression EXP cupric chloride results in increased expression of TXN mRNA CTD PMID:17211630 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507
JBrowse link
G TXNL1 thioredoxin like 1 increases expression EXP cupric chloride results in increased expression of TXNL1 mRNA CTD PMID:17211630 NCBI chr18:56,597,209...56,638,635
Ensembl chr18:56,597,209...56,651,600
JBrowse link
G TXNRD1 thioredoxin reductase 1 increases expression EXP cupric chloride results in increased expression of TXNRD1 mRNA CTD PMID:17211630 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
JBrowse link
G TYR tyrosinase multiple interactions EXP cupric chloride inhibits the reaction [bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]] CTD PMID:11092760 NCBI chr11:89,177,565...89,295,759
Ensembl chr11:89,177,875...89,295,759
JBrowse link
G UBA1 ubiquitin like modifier activating enzyme 1 multiple interactions EXP cupric chloride promotes the reaction [Dimethyldithiocarbamate results in decreased activity of and results in decreased ubiquitination of UBA1 protein]; cupric chloride results in decreased activity of and results in decreased ubiquitination of UBA1 protein CTD PMID:25714994 NCBI chr  X:47,190,847...47,215,128
Ensembl chr  X:47,190,861...47,215,128
JBrowse link
G UBC ubiquitin C increases expression EXP cupric chloride results in increased expression of UBC mRNA CTD PMID:17211630 NCBI chr12:124,911,646...124,914,650
Ensembl chr12:124,911,604...124,917,368
JBrowse link
G UBR5 ubiquitin protein ligase E3 component n-recognin 5 increases expression EXP cupric chloride results in increased expression of UBR5 mRNA CTD PMID:17211630 NCBI chr 8:102,252,273...102,412,700
Ensembl chr 8:102,252,273...102,412,759
JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 increases expression ISO cupric chloride results in increased expression of UCHL1 protein CTD PMID:29617964 NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455
JBrowse link
G UFD1 ubiquitin recognition factor in ER associated degradation 1 increases expression EXP cupric chloride results in increased expression of UFD1 mRNA CTD PMID:17211630 NCBI chr22:19,449,911...19,479,193
Ensembl chr22:19,449,911...19,479,202
JBrowse link
G UNKL unk like zinc finger increases expression EXP cupric chloride results in increased expression of UNKL mRNA CTD PMID:17211630 NCBI chr16:1,363,205...1,414,749
Ensembl chr16:1,363,205...1,414,751
JBrowse link
G UQCRC1 ubiquinol-cytochrome c reductase core protein 1 increases expression ISO cupric chloride results in increased expression of UQCRC1 protein CTD PMID:29617964 NCBI chr 3:48,599,002...48,609,664
Ensembl chr 3:48,599,002...48,610,976
JBrowse link
G UQCRH ubiquinol-cytochrome c reductase hinge protein decreases expression ISO cupric chloride results in decreased expression of UQCRH protein CTD PMID:29617964 NCBI chr 1:46,303,698...46,316,776
Ensembl chr 1:46,303,698...46,316,776
JBrowse link
G UTP11 UTP11 small subunit processome component increases expression EXP cupric chloride results in increased expression of UTP11 mRNA CTD PMID:17211630 NCBI chr 1:38,012,716...38,024,820
Ensembl chr 1:38,009,258...38,024,820
JBrowse link
G VDAC1 voltage dependent anion channel 1 increases expression ISO cupric chloride results in increased expression of VDAC1 protein CTD PMID:29617964 NCBI chr 5:133,971,871...134,070,987
Ensembl chr 5:133,971,871...134,004,975
JBrowse link
G VDAC2 voltage dependent anion channel 2 increases expression ISO cupric chloride results in increased expression of VDAC2 protein CTD PMID:29617964 NCBI chr10:75,210,170...75,231,448
Ensembl chr10:75,210,154...75,231,448
JBrowse link
G VEGFA vascular endothelial growth factor A increases expression EXP cupric chloride results in increased expression of VEGFA mRNA CTD PMID:15741220 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G VPS13B vacuolar protein sorting 13 homolog B affects expression EXP cupric chloride affects the expression of VPS13B mRNA CTD PMID:17211630 NCBI chr 8:99,013,274...99,877,580
Ensembl chr 8:99,013,266...99,877,580
JBrowse link
G WDR74 WD repeat domain 74 affects expression EXP cupric chloride affects the expression of WDR74 mRNA CTD PMID:17211630 NCBI chr11:62,832,905...62,841,809
Ensembl chr11:62,832,342...62,841,809
JBrowse link
G ZNF12 zinc finger protein 12 increases expression EXP cupric chloride results in increased expression of ZNF12 mRNA CTD PMID:17211630 NCBI chr 7:6,688,433...6,706,947
Ensembl chr 7:6,688,433...6,706,947
JBrowse link
G ZNF197 zinc finger protein 197 affects expression EXP cupric chloride affects the expression of ZNF197 mRNA CTD PMID:17211630 NCBI chr 3:44,625,036...44,648,471
Ensembl chr 3:44,584,888...44,648,471
JBrowse link
G ZNRD2 zinc ribbon domain containing 2 increases expression EXP cupric chloride results in increased expression of ZNRD2 mRNA CTD PMID:17211630 NCBI chr11:65,570,477...65,571,888
Ensembl chr11:65,570,460...65,573,942
JBrowse link
G ZSWIM6 zinc finger SWIM-type containing 6 affects expression EXP cupric chloride affects the expression of ZSWIM6 mRNA CTD PMID:17211630 NCBI chr 5:61,332,258...61,546,172
Ensembl chr 5:61,332,258...61,546,172
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 24513
    chemical entity 24481
      molecular entity 24446
        transition element molecular entity 17900
          copper group molecular entity 9864
            copper molecular entity 8792
              copper(II) chloride 292
                copper(II) chloride dihydrate 0
                copper(II) chloride pentahydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 24513
    subatomic particle 24471
      composite particle 24471
        hadron 24471
          baryon 24471
            nucleon 24471
              atomic nucleus 24471
                atom 24471
                  main group element atom 24329
                    p-block element atom 24329
                      halogen 19513
                        chlorine atom 19061
                          chlorine molecular entity 19061
                            elemental chlorine 8334
                              monoatomic chlorine 8317
                                chloride 8317
                                  chloride salt 8317
                                    inorganic chloride 8124
                                      copper(II) chloride 292
                                        copper(II) chloride dihydrate 0
                                        copper(II) chloride pentahydrate 0
paths to the root