CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: copper(II) chloride
Accession: CHEBI:49553
browse the term
Definition: An inorganic chloride of copper in which the metal is in the +2 oxidation state.
Synonyms: exact_synonym: copper(2+) dichloride
related_synonym: Coclor; Copper bichloride; Copper chloride; Copper chloride (CuCl2); Copper dichloride; Copper(2+)chloride; Copper(II) chloride (1:2); CuCl2; Cupric chloride; Cupric chloride anhydrous; Cupric dichloride; Formula=Cl2Cu; InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2; InChIKey=ORTQZVOHEJQUHG-UHFFFAOYSA-L; SMILES=Cl[Cu]Cl
xref: Beilstein:8128168; CAS:7447-39-4; DrugBank:DB09131; Drug_Central:4530; Gmelin:9300
xref_mesh: MESH:C029892
xref: PDBeChem:CUL; PMID:10444249; PMID:9730919; PPDB:174; Reaxys:8128168; Wikipedia:Copper(II)_chloride
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Aasdhppt
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
decreases expression
ISO
cupric chloride results in decreased expression of AASDHPPT mRNA
CTD
PMID:17211630
NCBI chr 8:1,453,226...1,463,990
Ensembl chr 8:1,452,282...1,463,966
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Abcf3
ATP binding cassette subfamily F member 3
increases expression
ISO
cupric chloride results in increased expression of ABCF3 mRNA
CTD
PMID:17211630
NCBI chr11:80,340,476...80,352,211
Ensembl chr11:80,339,977...80,352,211
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Abhd4
abhydrolase domain containing 4, N-acyl phospholipase B
increases expression
ISO
cupric chloride results in increased expression of ABHD4 mRNA
CTD
PMID:17211630
NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966
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Acat2
acetyl-CoA acetyltransferase 2
decreases expression
ISO
cupric chloride results in decreased expression of ACAT2 mRNA
CTD
PMID:34921933
NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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Ache
acetylcholinesterase
multiple interactions decreases activity
EXP ISO
cupric chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ACHE protein] Carnosine inhibits the reaction [cupric chloride results in decreased activity of ACHE protein]
CTD
PMID:24799335 PMID:32745495
NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
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Aco1
aconitase 1
decreases expression
ISO
cupric chloride results in decreased expression of ACO1 protein
CTD
PMID:29617964
NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
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Acss2
acyl-CoA synthetase short-chain family member 2
decreases expression
ISO
cupric chloride results in decreased expression of ACSS2 mRNA
CTD
PMID:34921933
NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
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Actb
actin, beta
increases expression
ISO
cupric chloride results in increased expression of ACTB protein
CTD
PMID:29617964
NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
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Adrm1
ADRM1 26S proteasome ubiquitin receptor
increases expression
ISO
cupric chloride results in increased expression of ADRM1 mRNA
CTD
PMID:17211630
NCBI chr 3:167,265,435...167,270,197
Ensembl chr 3:167,265,296...167,270,195
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Ahsg
alpha-2-HS-glycoprotein
decreases expression
ISO
cupric chloride results in decreased expression of AHSG mRNA
CTD
PMID:17211630
NCBI chr11:78,117,903...78,145,956
Ensembl chr11:78,117,918...78,145,999
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Akr1a1
aldo-keto reductase family 1 member A1
increases expression
ISO
cupric chloride results in increased expression of AKR1A1 protein
CTD
PMID:29617964
NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
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Alb
albumin
multiple interactions
ISO
ALB protein inhibits the reaction [cupric chloride results in decreased activity of PROC protein]
CTD
PMID:11820775
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Aldh1l1
aldehyde dehydrogenase 1 family, member L1
increases expression
ISO
cupric chloride results in increased expression of ALDH1L1 mRNA
CTD
PMID:17211630
NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465
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Aldoa
aldolase, fructose-bisphosphate A
increases expression
ISO
cupric chloride results in increased expression of ALDOA mRNA
CTD
PMID:17211630
NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
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Aldoc
aldolase, fructose-bisphosphate C
decreases expression increases expression
ISO
cupric chloride results in decreased expression of ALDOC protein cupric chloride results in increased expression of ALDOA protein
CTD
PMID:29617964
NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
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Alkbh2
alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase
decreases activity
ISO
cupric chloride results in decreased activity of ALKBH2 protein
CTD
PMID:28926697
NCBI chr12:42,494,187...42,500,929
Ensembl chr12:42,496,300...42,500,914
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Alkbh3
alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase
decreases activity
ISO
cupric chloride results in decreased activity of ALKBH3 protein
CTD
PMID:28926697
NCBI chr 3:79,939,515...79,972,820
Ensembl chr 3:79,939,600...79,972,000
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Ankrd1
ankyrin repeat domain 1
increases expression
ISO
cupric chloride results in increased expression of ANKRD1 mRNA
CTD
PMID:17211630
NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
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Anpep
alanyl aminopeptidase, membrane
decreases expression
ISO
cupric chloride results in decreased expression of ANPEP mRNA
CTD
PMID:17211630
NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789
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Apom
apolipoprotein M
increases expression
ISO
cupric chloride results in increased expression of APOM mRNA
CTD
PMID:17211630
NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550
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App
amyloid beta precursor protein
increases expression multiple interactions
EXP ISO
cupric chloride results in increased expression of APP mRNA; cupric chloride results in increased expression of APP protein cupric chloride results in decreased uptake of and results in decreased degradation of APP protein modified form cupric chloride results in decreased uptake of and results in decreased degradation of APP protein modified form; PP242 inhibits the reaction [cupric chloride results in decreased uptake of and results in decreased degradation of APP protein modified form]
CTD
PMID:22542740 PMID:32512069
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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Ar
androgen receptor
multiple interactions
ISO
[Disulfiram co-treated with cupric chloride] results in decreased expression of AR protein
CTD
PMID:19789329
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Atf2
activating transcription factor 2
multiple interactions
ISO
[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein]
CTD
PMID:30768131
NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
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Atf4
activating transcription factor 4
multiple interactions
EXP
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA]
CTD
PMID:20920558
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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Atm
ATM serine/threonine kinase
multiple interactions
ISO
cupric chloride results in increased phosphorylation of and results in increased activity of ATM protein
CTD
PMID:16959548
NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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Atox1
antioxidant 1 copper chaperone
multiple interactions
ISO
[cupric chloride results in increased abundance of Copper] which results in increased expression of ATOX1 mRNA; ATOX1 protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper]
CTD
PMID:32278528
NCBI chr10:39,564,855...39,579,892
Ensembl chr10:39,564,857...39,579,950
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Atp7a
ATPase copper transporting alpha
increases transport multiple interactions affects localization decreases glutathionylation increases expression
ISO EXP
ATP7A protein results in increased transport of cupric chloride ATP7A protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper]; ATP7A protein results in decreased uptake of [cupric chloride results in increased abundance of Copper]; cupric chloride inhibits the reaction [bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]]; cupric chloride promotes the reaction [CLU protein binds to ATP7A protein] Omeprazole inhibits the reaction [cupric chloride affects the localization of ATP7A protein] cupric chloride results in decreased glutathionylation of ATP7A protein cupric chloride inhibits the reaction [Cycloheximide results in decreased expression of ATP7A protein]; cupric chloride promotes the reaction [Deferoxamine results in increased expression of ATP7A mRNA]; Deferoxamine promotes the reaction [cupric chloride results in increased expression of ATP7A protein]
CTD
PMID:11092760 PMID:16317117 PMID:17009961 PMID:20566629 PMID:21242307 PMID:23174565 PMID:25337692 PMID:32278528 More...
NCBI chr X:71,094,144...71,201,550
Ensembl chr X:71,094,202...71,198,354
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Atp7b
ATPase copper transporting beta
decreases response to substance affects localization multiple interactions
ISO EXP
ATP7B protein results in decreased susceptibility to cupric chloride cupric chloride affects the localization of ATP7B protein ATP7B protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper]; ATP7B protein results in increased uptake of [cupric chloride results in increased abundance of Copper]; cupric chloride promotes the reaction [CLU protein binds to ATP7B protein]
CTD
PMID:10728692 PMID:16799059 PMID:21242307 PMID:24343273 PMID:32278528
NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
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Bace1
beta-secretase 1
increases expression
EXP
cupric chloride results in increased expression of BACE1 mRNA; cupric chloride results in increased expression of BACE1 protein
CTD
PMID:22542740
NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
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Bag3
BAG cochaperone 3
increases expression
ISO
cupric chloride results in increased expression of BAG3 mRNA
CTD
PMID:17211630
NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
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Bax
BCL2 associated X, apoptosis regulator
increases expression multiple interactions
ISO
cupric chloride results in increased expression of BAX protein [cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein; [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased expression of BAX protein; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; Ethanol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; neocuproine inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; Thiourea inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]
CTD
PMID:21035945 PMID:22239859 PMID:23313662 PMID:24170445 PMID:29803612
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2
BCL2, apoptosis regulator
multiple interactions decreases expression
EXP ISO
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein] cupric chloride results in decreased expression of BCL2 protein [Disulfiram co-treated with cupric chloride] results in decreased expression of BCL2 protein
CTD
PMID:20920558 PMID:21911303 PMID:23313662 PMID:24170445
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bcl2l1
Bcl2-like 1
decreases expression
ISO
cupric chloride results in decreased expression of BCL2L1 protein
CTD
PMID:23313662 PMID:24170445
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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Bid
BH3 interacting domain death agonist
increases expression
ISO
cupric chloride results in increased expression of BID mRNA
CTD
PMID:17211630
NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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Blvrb
biliverdin reductase B
increases expression
ISO
cupric chloride results in increased expression of BLVRB mRNA
CTD
PMID:17211630
NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
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C1qtnf4
C1q and TNF related 4
increases expression
ISO
cupric chloride results in increased expression of C1QTNF4 mRNA
CTD
PMID:17211630
NCBI chr 3:76,854,368...76,872,991
Ensembl chr 3:76,857,735...76,874,139
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Casp3
caspase 3
multiple interactions increases activity decreases activity increases expression
EXP ISO
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein; [Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein] cupric chloride results in increased activity of CASP3 protein cupric chloride results in decreased activity of CASP3 protein cupric chloride results in increased expression of CASP3 protein [cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein; [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP3 protein; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; Ethanol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; neocuproine inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; Thiourea inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]
CTD
PMID:11239917 PMID:18056745 PMID:20920558 PMID:21035945 PMID:22954531 PMID:23313662 PMID:24170445 PMID:29803612 More...
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp7
caspase 7
multiple interactions
EXP ISO
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein] [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP7 protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP7 protein]
CTD
PMID:20920558 PMID:21035945
NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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Casp8
caspase 8
increases expression
ISO
cupric chloride results in increased expression of CASP8 protein
CTD
PMID:23313662
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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Casp9
caspase 9
multiple interactions increases expression
EXP ISO
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein] cupric chloride results in increased expression of CASP9 protein
CTD
PMID:20920558 PMID:23313662 PMID:24170445
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Cat
catalase
multiple interactions decreases activity
ISO
Carnosine inhibits the reaction [cupric chloride results in decreased activity of CAT protein]; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein]; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]
CTD
PMID:29803612 PMID:32745495
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccn1
cellular communication network factor 1
increases expression
ISO
cupric chloride results in increased expression of CCN1 mRNA
CTD
PMID:17211630
NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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Ccs
copper chaperone for superoxide dismutase
multiple interactions
ISO
cupric chloride results in increased degradation of and results in decreased expression of CCS protein
CTD
PMID:16531609
NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:202,113,804...202,134,915
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Cd63
Cd63 molecule
decreases expression
ISO
cupric chloride results in decreased expression of CD63 mRNA
CTD
PMID:17211630
NCBI chr 7:1,325,108...1,340,447
Ensembl chr 7:1,325,103...1,399,178
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Cdc34
cell division cycle 34, ubiqiutin conjugating enzyme
affects expression
ISO
cupric chloride affects the expression of CDC34 mRNA
CTD
PMID:17211630
NCBI chr 7:10,017,588...10,023,586
Ensembl chr 7:10,017,588...10,023,186
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
affects expression
ISO
cupric chloride affects the expression of CDKN1A mRNA
CTD
PMID:17211630
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cdkn1b
cyclin-dependent kinase inhibitor 1B
affects expression
ISO
cupric chloride affects the expression of CDKN1B protein
CTD
PMID:23313662
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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Chordc1
cysteine and histidine rich domain containing 1
increases expression
ISO
cupric chloride results in increased expression of CHORDC1 mRNA
CTD
PMID:17211630
NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
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Ckmt2
creatine kinase, mitochondrial 2
decreases expression
ISO
cupric chloride results in decreased expression of CKMT2 protein
CTD
PMID:29617964
NCBI chr 2:23,079,920...23,110,518
Ensembl chr 2:23,079,918...23,110,430
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Cks2
CDC28 protein kinase regulatory subunit 2
increases expression
ISO
cupric chloride results in increased expression of CKS2 mRNA
CTD
PMID:17211630
NCBI chr17:13,570,611...13,575,770
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Clcn6
chloride voltage-gated channel 6
increases expression decreases expression
ISO
cupric chloride results in increased expression of CLCN6 mRNA cupric chloride results in decreased expression of CLCN6 mRNA
CTD
PMID:17211630 PMID:34921933
NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
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Clcn7
chloride voltage-gated channel 7
affects expression
ISO
cupric chloride affects the expression of CLCN7 mRNA
CTD
PMID:17211630
NCBI chr10:14,151,758...14,177,130
Ensembl chr10:14,151,758...14,177,130
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Cldnd1
claudin domain containing 1
increases expression
ISO
cupric chloride results in increased expression of CLDND1 mRNA
CTD
PMID:17211630
NCBI chr11:41,883,120...41,889,471
Ensembl chr11:41,883,134...41,889,354
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Clu
clusterin
multiple interactions increases expression
ISO
cupric chloride promotes the reaction [CLU protein binds to ATP7A protein]; cupric chloride promotes the reaction [CLU protein binds to ATP7B protein] cupric chloride results in increased expression of CLU mRNA
CTD
PMID:17211630 PMID:21242307
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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Commd1
copper metabolism domain containing 1
decreases response to substance decreases expression multiple interactions
ISO EXP
COMMD1 protein results in decreased susceptibility to cupric chloride cupric chloride results in decreased expression of COMMD1 mRNA; cupric chloride results in decreased expression of COMMD1 protein [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK2 protein; [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein cupric chloride promotes the reaction [COMMD1 protein binds to SOD1 protein]
CTD
PMID:17211630 PMID:24691167 PMID:25007851
NCBI chr14:96,880,463...96,984,494
Ensembl chr14:96,880,463...96,984,501
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Commd10
COMM domain containing 10
decreases expression
ISO
cupric chloride results in decreased expression of COMMD10 mRNA
CTD
PMID:17211630
NCBI chr18:39,741,219...39,874,801
Ensembl chr18:39,741,298...39,874,903
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Commd2
COMM domain containing 2
decreases expression
ISO
cupric chloride results in decreased expression of COMMD2 mRNA
CTD
PMID:17211630
NCBI chr 2:141,848,661...141,852,907
Ensembl chr 2:141,848,680...141,852,888
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Commd3
COMM domain containing 3
decreases expression
ISO
cupric chloride results in decreased expression of COMMD3 mRNA
CTD
PMID:17211630
NCBI chr17:81,327,451...81,331,183
Ensembl chr17:81,327,405...81,331,177
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Commd4
COMM domain containing 4
decreases expression
ISO
cupric chloride results in decreased expression of COMMD4 mRNA
CTD
PMID:17211630
NCBI chr 8:57,566,236...57,569,794
Ensembl chr 8:57,566,236...57,569,760
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Commd5
COMM domain containing 5
decreases expression
ISO
cupric chloride results in decreased expression of COMMD5 mRNA
CTD
PMID:17211630
NCBI chr 7:108,621,766...108,623,616
Ensembl chr 7:108,598,673...108,624,764
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Commd6
COMM domain containing 6
decreases expression
ISO
cupric chloride results in decreased expression of COMMD6 mRNA
CTD
PMID:17211630
NCBI chr15:78,467,333...78,474,382
Ensembl chr15:78,467,804...78,474,382
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Commd7
COMM domain containing 7
decreases expression
ISO
cupric chloride results in decreased expression of COMMD7 mRNA
CTD
PMID:17211630
NCBI chr 3:142,099,566...142,114,348
Ensembl chr 3:142,099,251...142,114,317
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Commd8
COMM domain containing 8
decreases expression
ISO
cupric chloride results in decreased expression of COMMD8 mRNA
CTD
PMID:17211630
NCBI chr14:36,049,040...36,059,617
Ensembl chr14:36,049,004...36,059,617
G
Cox16
cytochrome c oxidase assembly factor COX16
affects expression
ISO
cupric chloride affects the expression of COX16 mRNA
CTD
PMID:17211630
NCBI chr 6:101,162,231...101,181,277
Ensembl chr 6:101,019,680...101,181,246
G
Cox5b
cytochrome c oxidase subunit 5B
decreases expression
ISO
cupric chloride results in decreased expression of COX5B protein
CTD
PMID:29617964
NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052
G
Cox6a1
cytochrome c oxidase subunit 6A1
increases expression
ISO
cupric chloride results in increased expression of COX6A1 protein
CTD
PMID:29617964
NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041
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Cp
ceruloplasmin
increases expression
ISO
cupric chloride results in increased expression of CP mRNA
CTD
PMID:15741220
NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
G
Cplx2
complexin 2
decreases expression
ISO
cupric chloride results in decreased expression of CPLX2 protein
CTD
PMID:29617964
NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855
G
Cryab
crystallin, alpha B
increases expression
ISO
cupric chloride results in increased expression of CRYAB mRNA
CTD
PMID:17211630
NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
G
Csnk1g1
casein kinase 1, gamma 1
decreases expression
ISO
cupric chloride results in decreased expression of CSNK1G1 mRNA
CTD
PMID:34921933
NCBI chr 8:66,439,760...66,577,247
Ensembl chr 8:66,439,864...66,572,826
G
Cstb
cystatin B
affects binding
ISO
CSTB protein binds to cupric chloride
CTD
PMID:16939620
NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526
G
Ctsb
cathepsin B
multiple interactions decreases expression
ISO
PP242 inhibits the reaction [cupric chloride results in decreased expression of CTSB mRNA]; PP242 inhibits the reaction [cupric chloride results in decreased expression of CTSB protein] cupric chloride results in decreased expression of CTSB mRNA; cupric chloride results in decreased expression of CTSB protein
CTD
PMID:32512069
NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
G
Ctsd
cathepsin D
decreases expression multiple interactions
ISO
cupric chloride results in decreased expression of CTSD mRNA PP242 inhibits the reaction [cupric chloride results in decreased expression of CTSD mRNA]
CTD
PMID:32512069
NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
G
Cybc1
cytochrome b-245 chaperone 1
increases expression
ISO
cupric chloride results in increased expression of CYBC1 mRNA
CTD
PMID:34921933
NCBI chr10:106,498,730...106,505,549
Ensembl chr10:106,498,725...106,505,596
G
Cycs
cytochrome c, somatic
multiple interactions
EXP
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which affects the localization of CYCS protein
CTD
PMID:20920558
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
G
Cyfip2
cytoplasmic FMR1 interacting protein 2
decreases expression
ISO
cupric chloride results in decreased expression of CYFIP2 mRNA
CTD
PMID:17211630
NCBI chr10:30,621,318...30,741,113
Ensembl chr10:30,621,318...30,741,113
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases stability multiple interactions
ISO
cupric chloride results in increased stability of CYP1A1 mRNA; cupric chloride results in increased stability of CYP1A1 protein [1,10-phenanthroline co-treated with cupric chloride] inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; [1,10-phenanthroline co-treated with cupric chloride] inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]
CTD
PMID:19896525
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
G
Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
increases expression
ISO
cupric chloride results in increased expression of CYP27A1 mRNA
CTD
PMID:17211630
NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
G
Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
multiple interactions
ISO
[CYP2B6 protein co-treated with cupric chloride co-treated with NADP] results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; [CYP2B6 protein co-treated with cupric chloride co-treated with NADP] results in increased metabolism of N'-nitrosonornicotine
CTD
PMID:32672941
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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Cyp2c6v1
cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1
increases expression
ISO
cupric chloride results in increased expression of CYP2C38 mRNA
CTD
PMID:17211630
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
G
Cyp51
cytochrome P450, family 51
decreases expression
ISO
cupric chloride results in decreased expression of CYP51A1 mRNA
CTD
PMID:34921933
NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
G
Ddit3
DNA-damage inducible transcript 3
multiple interactions increases expression
EXP ISO
pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of DDIT3 mRNA] cupric chloride results in increased expression of DDIT3 mRNA
CTD
PMID:17211630 PMID:20920558
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
G
Derl3
derlin 3
decreases expression
ISO
cupric chloride results in decreased expression of DERL3 mRNA
CTD
PMID:34921933
NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027
G
Dhcr7
7-dehydrocholesterol reductase
decreases expression
ISO
cupric chloride results in decreased expression of DHCR7 mRNA
CTD
PMID:34921933
NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
G
Dkk1
dickkopf WNT signaling pathway inhibitor 1
increases expression
ISO
cupric chloride results in increased expression of DKK1 mRNA
CTD
PMID:17211630
NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
G
Dmd
dystrophin
increases expression
ISO
cupric chloride results in increased expression of DMD mRNA
CTD
PMID:17211630
NCBI chr X:47,272,324...49,504,219
Ensembl chr X:47,272,331...49,504,207
G
Dnajb1
DnaJ heat shock protein family (Hsp40) member B1
increases expression
ISO
cupric chloride results in increased expression of DNAJB1 mRNA
CTD
PMID:17211630
NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458
G
Dpysl2
dihydropyrimidinase-like 2
increases expression
ISO
cupric chloride results in increased expression of DPYSL2 protein
CTD
PMID:29617964
NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829
G
Dpysl5
dihydropyrimidinase-like 5
increases expression
ISO
cupric chloride results in increased expression of DPYSL5 protein
CTD
PMID:29617964
NCBI chr 6:25,575,104...25,659,422
Ensembl chr 6:25,575,104...25,659,422
G
Dusp1
dual specificity phosphatase 1
increases expression
ISO
cupric chloride results in increased expression of DUSP1 mRNA
CTD
PMID:17211630
NCBI chr10:16,680,489...16,683,276
G
Ebp
EBP, cholestenol delta-isomerase
decreases expression
ISO
cupric chloride results in decreased expression of EBP mRNA
CTD
PMID:34921933
NCBI chr X:14,299,427...14,305,826
Ensembl chr X:14,299,448...14,305,826
G
Egr1
early growth response 1
affects expression
ISO
cupric chloride affects the expression of EGR1 mRNA
CTD
PMID:17211630
NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
G
Elac2
elaC ribonuclease Z 2
affects expression
ISO
cupric chloride affects the expression of ELAC2 mRNA
CTD
PMID:17211630
NCBI chr10:49,632,308...49,655,614
Ensembl chr10:49,632,378...49,655,614
G
Elovl1
ELOVL fatty acid elongase 1
increases expression
ISO
cupric chloride results in increased expression of ELOVL1 mRNA
CTD
PMID:17211630
NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958
G
Elovl6
ELOVL fatty acid elongase 6
decreases expression
ISO
cupric chloride results in decreased expression of ELOVL6 mRNA
CTD
PMID:34921933
NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
G
Eml4
EMAP like 4
decreases expression
ISO
cupric chloride results in decreased expression of EML4 mRNA
CTD
PMID:17211630
NCBI chr 6:11,219,545...11,334,824
Ensembl chr 6:11,219,566...11,334,879
G
Enam
enamelin
affects expression
ISO
cupric chloride affects the expression of ENAM mRNA
CTD
PMID:17211630
NCBI chr14:19,556,729...19,581,433
Ensembl chr14:19,556,729...19,581,425
G
Endog
endonuclease G
increases expression
ISO
cupric chloride results in increased expression of ENDOG protein
CTD
PMID:22239859
NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932
G
Erg28
ergosterol biosynthesis 28 homolog
decreases expression
ISO
cupric chloride results in decreased expression of ERG28 mRNA
CTD
PMID:34921933
NCBI chr 6:105,474,112...105,483,078
Ensembl chr 6:105,474,113...105,483,078
G
Esr1
estrogen receptor 1
multiple interactions decreases expression affects response to substance increases activity
ISO
cupric chloride inhibits the reaction [Estradiol binds to ESR1 protein]; cupric chloride promotes the reaction [Estradiol results in decreased expression of ESR1 mRNA]; cupric chloride promotes the reaction [Estradiol results in decreased expression of ESR1 protein]; Estradiol promotes the reaction [cupric chloride results in decreased expression of ESR1 mRNA]; Estradiol promotes the reaction [cupric chloride results in decreased expression of ESR1 protein] cupric chloride results in decreased expression of ESR1 mRNA; cupric chloride results in decreased expression of ESR1 protein ESR1 protein affects the susceptibility to cupric chloride cupric chloride results in increased activity of ESR1 protein
CTD
PMID:12746304 PMID:17716812
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
F2
coagulation factor II
increases expression
ISO
cupric chloride results in increased expression of F2 mRNA
CTD
PMID:17211630
NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
G
Fam219a
family with sequence similarity 219, member A
increases expression
ISO
cupric chloride results in increased expression of FAM219A mRNA
CTD
PMID:17211630
NCBI chr 5:56,679,272...56,729,959
Ensembl chr 5:56,680,613...56,729,924
G
Fam89b
family with sequence similarity 89, member B
increases expression
ISO
cupric chloride results in increased expression of FAM89B mRNA
CTD
PMID:17211630
NCBI chr 1:203,015,772...203,017,890
Ensembl chr 1:203,015,773...203,017,367
G
Fasn
fatty acid synthase
decreases expression
ISO
cupric chloride results in decreased expression of FASN mRNA
CTD
PMID:34921933
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
G
Fdft1
farnesyl diphosphate farnesyl transferase 1
decreases expression
ISO
cupric chloride results in decreased expression of FDFT1 mRNA
CTD
PMID:34921933
NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
G
Fetub
fetuin B
increases expression
ISO
cupric chloride results in increased expression of FETUB mRNA
CTD
PMID:17211630
NCBI chr11:78,082,158...78,093,022
Ensembl chr11:78,082,156...78,095,135
G
Fgf1
fibroblast growth factor 1
multiple interactions
ISO
[amlexanox binds to FGF1 protein] inhibits the reaction [cupric chloride results in increased oxidation of FGF1 protein]
CTD
PMID:16300395
NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
G
Fgfr1
Fibroblast growth factor receptor 1
affects expression
ISO
cupric chloride affects the expression of FGFR1 mRNA
CTD
PMID:17211630
NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
G
Fhl3
four and a half LIM domains 3
increases expression
ISO
cupric chloride results in increased expression of FHL3 mRNA
CTD
PMID:17211630
NCBI chr 5:136,953,947...136,961,317
Ensembl chr 5:136,950,411...136,961,317
G
Fkbp4
FKBP prolyl isomerase 4
increases expression
ISO
cupric chloride results in increased expression of FKBP4 mRNA
CTD
PMID:17211630
NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833
G
Fmo5
flavin containing dimethylaniline monoxygenase 5
decreases expression
ISO
cupric chloride results in decreased expression of FMO5 mRNA
CTD
PMID:17211630
NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
cupric chloride results in increased expression of FOS mRNA
CTD
PMID:17211630
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
G
Fubp1
far upstream element binding protein 1
increases expression
ISO
cupric chloride results in increased expression of FUBP1 protein
CTD
PMID:29617964
NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
G
Fxyd2
FXYD domain-containing ion transport regulator 2
affects expression
ISO
cupric chloride affects the expression of FXYD2 mRNA
CTD
PMID:17211630
NCBI chr 8:45,712,887...45,720,032
Ensembl chr 8:45,712,903...45,720,203
G
G6pd
glucose-6-phosphate dehydrogenase
decreases activity multiple interactions
ISO
cupric chloride results in decreased activity of G6PD protein Carnosine inhibits the reaction [cupric chloride results in decreased activity of G6PD protein]
CTD
PMID:32745495
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
G
Gabre
gamma-aminobutyric acid type A receptor subunit epsilon
increases expression
ISO
cupric chloride results in increased expression of GABRE mRNA
CTD
PMID:17211630
NCBI chr X:150,060,035...150,078,773
Ensembl chr X:150,060,040...150,078,693
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
ISO
cupric chloride results in increased expression of GADD45A mRNA
CTD
PMID:17211630
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression
ISO
cupric chloride results in increased expression of GCLC mRNA
CTD
PMID:17211630
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression
ISO
cupric chloride results in increased expression of GCLM mRNA
CTD
PMID:17211630 PMID:24343273
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
G
Gdi1
GDP dissociation inhibitor 1
increases expression
ISO
cupric chloride results in increased expression of GDI1 protein
CTD
PMID:29617964
NCBI chr X:152,087,611...152,094,274
Ensembl chr X:152,087,444...152,094,272
G
Gla
galactosidase, alpha
increases expression
ISO
cupric chloride results in increased expression of GLA mRNA
CTD
PMID:17211630
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
G
Glud1
glutamate dehydrogenase 1
decreases expression
ISO
cupric chloride results in decreased expression of GLUD1 mRNA
CTD
PMID:17211630
NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
G
Gprc5c
G protein-coupled receptor, class C, group 5, member C
decreases expression
ISO
cupric chloride results in decreased expression of GPRC5C mRNA
CTD
PMID:34921933
NCBI chr10:99,886,900...99,908,928
Ensembl chr10:99,887,077...99,908,926
G
Gsr
glutathione-disulfide reductase
multiple interactions decreases activity
ISO
Carnosine inhibits the reaction [cupric chloride results in decreased activity of GSR protein]
CTD
PMID:32745495
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
G
Gtpbp2
GTP binding protein 2
affects expression
ISO
cupric chloride affects the expression of GTPBP2 mRNA
CTD
PMID:17211630
NCBI chr 9:14,813,964...14,823,419
Ensembl chr 9:14,813,964...14,823,241
G
Gtpbp6
GTP binding protein 6 (putative)
increases expression
ISO
cupric chloride results in increased expression of GTPBP6 mRNA
CTD
PMID:17211630
NCBI chr12:46,574,913...46,578,873
Ensembl chr12:46,574,435...46,578,873
G
Hamp
hepcidin antimicrobial peptide
increases expression
ISO
cupric chloride results in increased expression of HAMP mRNA
CTD
PMID:17211630
NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
G
Hexa
hexosaminidase subunit alpha
decreases expression multiple interactions
ISO
cupric chloride results in decreased expression of HEXA mRNA PP242 inhibits the reaction [cupric chloride results in decreased expression of HEXA mRNA]
CTD
PMID:32512069
NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013
G
Hif1a
hypoxia inducible factor 1 subunit alpha
multiple interactions decreases hydroxylation affects localization increases stability
ISO
Ascorbic Acid inhibits the reaction [cupric chloride results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [cupric chloride results in increased stability of HIF1A protein]; cupric chloride results in decreased hydroxylation of and results in decreased degradation of HIF1A protein cupric chloride affects the localization of HIF1A protein
CTD
PMID:15741220 PMID:19074761
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
G
Hk1
hexokinase 1
decreases activity
EXP
cupric chloride results in decreased activity of HK1 protein
CTD
PMID:22349057
NCBI chr20:30,230,488...30,332,161
Ensembl chr20:30,230,486...30,332,131
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
decreases expression
ISO
cupric chloride results in decreased expression of HMGCR mRNA
CTD
PMID:34921933
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
G
Hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1
decreases expression
ISO
cupric chloride results in decreased expression of HMGCS1 mRNA
CTD
PMID:34921933
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
G
Hmox1
heme oxygenase 1
increases expression
ISO
cupric chloride results in increased expression of HMOX1 mRNA; cupric chloride results in increased expression of HMOX1 protein
CTD
PMID:17211630 PMID:21242307 PMID:24343273
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Hsd17b7
hydroxysteroid (17-beta) dehydrogenase 7
decreases expression
ISO
cupric chloride results in decreased expression of HSD17B7 mRNA
CTD
PMID:34921933
NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017
G
Hsp90aa1
heat shock protein 90 alpha family class A member 1
increases expression
ISO
cupric chloride results in increased expression of HSP90AA1 mRNA
CTD
PMID:17211630
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
G
Hsp90b1
heat shock protein 90 beta family member 1
multiple interactions
EXP
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA]
CTD
PMID:20920558
NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
G
Hspa1a
heat shock protein family A (Hsp70) member 1A
affects expression
ISO
cupric chloride affects the expression of HSPA1A mRNA
CTD
PMID:20945374
G
Hspa1b
heat shock protein family A (Hsp70) member 1B
increases expression
ISO
cupric chloride results in increased expression of HSPA1B mRNA
CTD
PMID:17211630
NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
G
Hspa5
heat shock protein family A (Hsp70) member 5
multiple interactions
EXP
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA]
CTD
PMID:20920558
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
G
Hspa6l-ps1
heat shock protein family A (Hsp70) member 6 like, pseudogene 1
increases expression
ISO
cupric chloride results in increased expression of HSPA6 mRNA
CTD
PMID:17211630
NCBI chr13:83,271,340...83,275,267
G
Hspa9
heat shock protein family A (Hsp70) member 9
decreases expression
ISO
cupric chloride results in decreased expression of HSPA9 protein
CTD
PMID:29617964
NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
G
Hspb1
heat shock protein family B (small) member 1
increases expression
ISO
cupric chloride results in increased expression of HSPB1 mRNA
CTD
PMID:17211630
NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
G
Id2
inhibitor of DNA binding 2
affects expression
ISO
cupric chloride affects the expression of ID2 mRNA
CTD
PMID:17211630
NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
G
Idh3a
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
decreases expression
ISO
cupric chloride results in decreased expression of IDH3A protein
CTD
PMID:29617964
NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
G
Idi1
isopentenyl-diphosphate delta isomerase 1
decreases expression
ISO
cupric chloride results in decreased expression of IDI1 mRNA
CTD
PMID:34921933
NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
G
Ier2
immediate early response 2
increases expression
ISO
cupric chloride results in increased expression of IER2 mRNA
CTD
PMID:17211630
NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211
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Ier5
immediate early response 5
increases expression
ISO
cupric chloride results in increased expression of IER5 mRNA
CTD
PMID:17211630
NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227
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Ifng
interferon gamma
multiple interactions
ISO
cupric chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]]
CTD
PMID:8975779
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Igf1
insulin-like growth factor 1
increases expression
ISO
cupric chloride results in increased expression of IGF1 mRNA
CTD
PMID:17211630
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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Ighmbp2
immunoglobulin mu DNA binding protein 2
increases expression
ISO
cupric chloride results in increased expression of IGHMBP2 mRNA
CTD
PMID:17211630
NCBI chr 1:200,506,641...200,529,293
Ensembl chr 1:200,506,338...200,529,514
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Ikbkg
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
increases expression
ISO
cupric chloride results in increased expression of IKBKG mRNA
CTD
PMID:17211630
NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499
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Il1a
interleukin 1 alpha
increases secretion
ISO
cupric chloride results in increased secretion of IL1A protein
CTD
PMID:22954531
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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Il6
interleukin 6
multiple interactions
ISO
cupric chloride inhibits the reaction [TNF protein results in increased secretion of IL6 protein]
CTD
PMID:23285694
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Immt
inner membrane mitochondrial protein
decreases expression
ISO
cupric chloride results in decreased expression of IMMT protein
CTD
PMID:29617964
NCBI chr 4:103,880,482...103,919,116
Ensembl chr 4:103,880,459...103,919,109
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Irs2
insulin receptor substrate 2
increases expression
ISO
cupric chloride results in increased expression of IRS2 mRNA
CTD
PMID:17211630
NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases expression multiple interactions
ISO
cupric chloride results in increased expression of JUN mRNA [Disulfiram co-treated with cupric chloride co-treated with Doxorubicin] results in increased expression of and results in increased phosphorylation of JUN protein [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of JUN protein]
CTD
PMID:17211630 PMID:21911303 PMID:30768131
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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Kcnip1
potassium voltage-gated channel interacting protein 1
increases expression
ISO
cupric chloride results in increased expression of KCNIP1 mRNA
CTD
PMID:34921933
NCBI chr10:18,219,519...18,588,833
Ensembl chr10:18,219,519...18,589,045
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Kdm2a
lysine demethylase 2A
increases expression
ISO
cupric chloride results in increased expression of KDM2A mRNA
CTD
PMID:17211630
NCBI chr 1:201,612,427...201,682,359
Ensembl chr 1:201,612,453...201,680,787
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Kdm3a
lysine demethylase 3A
increases expression
ISO
cupric chloride results in increased expression of KDM3A mRNA
CTD
PMID:17211630
NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073
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Kif5a
kinesin family member 5A
decreases activity multiple interactions
ISO
cupric chloride results in decreased activity of KIF5A protein Cysteine inhibits the reaction [cupric chloride results in decreased activity of KIF5A protein]; Dithiothreitol inhibits the reaction [cupric chloride results in decreased activity of KIF5A protein]; Egtazic Acid inhibits the reaction [cupric chloride results in decreased activity of KIF5A protein]
CTD
PMID:24853401
NCBI chr 7:63,051,894...63,089,024
Ensembl chr 7:63,049,424...63,092,858
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Klf6
Kruppel-like factor 6
affects expression
ISO
cupric chloride affects the expression of KLF6 mRNA
CTD
PMID:17211630
NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
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Kng2
kininogen 2
increases expression
ISO
cupric chloride results in increased expression of KNG1 mRNA; cupric chloride results in increased expression of KNG2 mRNA
CTD
PMID:17211630
NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971
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Lamp1
lysosomal-associated membrane protein 1
decreases expression multiple interactions
ISO
cupric chloride results in decreased expression of LAMP1 mRNA; cupric chloride results in decreased expression of LAMP1 protein PP242 inhibits the reaction [cupric chloride results in decreased expression of LAMP1 mRNA]; PP242 inhibits the reaction [cupric chloride results in decreased expression of LAMP1 protein]
CTD
PMID:32512069
NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
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Lamp2
lysosomal-associated membrane protein 2
decreases expression multiple interactions
ISO
cupric chloride results in decreased expression of LAMP2 mRNA PP242 inhibits the reaction [cupric chloride results in decreased expression of LAMP2 mRNA]
CTD
PMID:32512069
NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522
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Lcat
lecithin cholesterol acyltransferase
increases expression
ISO
cupric chloride results in increased expression of LCAT mRNA
CTD
PMID:17211630
NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
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Lox
lysyl oxidase
increases activity multiple interactions
ISO
cupric chloride results in increased activity of LOX protein Aminopropionitrile inhibits the reaction [cupric chloride results in increased activity of LOX protein]
CTD
PMID:22367676 PMID:25044713
NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
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Ly6e
lymphocyte antigen 6 family member E
increases expression
ISO
cupric chloride results in increased expression of LY6E mRNA
CTD
PMID:17211630
NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689
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Mad2l1bp
MAD2L1 binding protein
increases expression
ISO
cupric chloride results in increased expression of MAD2L1BP mRNA
CTD
PMID:17211630
NCBI chr 9:14,832,133...14,836,458
Ensembl chr 9:14,832,132...14,837,447
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Mafg
MAF bZIP transcription factor G
increases expression
ISO
cupric chloride results in increased expression of MAFG mRNA
CTD
PMID:17211630
NCBI chr10:105,903,307...105,911,845
Ensembl chr10:105,903,237...105,912,026
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Map1lc3b
microtubule-associated protein 1 light chain 3 beta
increases expression multiple interactions
ISO
cupric chloride results in increased expression of MAP1LC3B mRNA cupric chloride results in increased expression of MAP1LC3B protein modified form Acetylcysteine inhibits the reaction [cupric chloride results in increased expression of MAP1LC3B protein modified form]; cupric chloride inhibits the reaction [3-methyladenine results in decreased expression of MAP1LC3B protein modified form]; PP242 promotes the reaction [cupric chloride results in increased expression of MAP1LC3B protein modified form]
CTD
PMID:17211630 PMID:32512069
NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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Mapk1
mitogen activated protein kinase 1
multiple interactions
EXP
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK1 protein
CTD
PMID:20920558
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
multiple interactions
EXP
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK3 protein
CTD
PMID:20920558
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mapk8
mitogen-activated protein kinase 8
multiple interactions
EXP ISO
[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein] [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein]
CTD
PMID:11239917 PMID:20920558 PMID:30768131
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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Mcm2
minichromosome maintenance complex component 2
multiple interactions
ISO
cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM2 mRNA]
CTD
PMID:19789329
NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
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Mcm5
minichromosome maintenance complex component 5
multiple interactions
ISO
cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM5 mRNA]
CTD
PMID:19789329
NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
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Mdh2
malate dehydrogenase 2
increases expression
ISO
cupric chloride results in increased expression of MDH2 protein
CTD
PMID:29617964
NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271
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Med15
mediator complex subunit 15
increases expression
ISO
cupric chloride results in increased expression of MED15 mRNA
CTD
PMID:17211630
NCBI chr11:83,280,722...83,356,006
Ensembl chr11:83,280,762...83,355,362
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Mgmt
O-6-methylguanine-DNA methyltransferase
multiple interactions
ISO
[Disulfiram co-treated with cupric chloride] affects the expression of and affects the activity of MGMT protein
CTD
PMID:24193513
NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
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Mllt11
MLLT11, transcription factor 7 cofactor
increases expression
ISO
cupric chloride results in increased expression of MLLT11 mRNA
CTD
PMID:17211630
NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199
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Mmp2
matrix metallopeptidase 2
increases secretion
EXP
cupric chloride results in increased secretion of MMP2 protein
CTD
PMID:11045606
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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Mrpl4
mitochondrial ribosomal protein L4
increases expression
ISO
cupric chloride results in increased expression of MRPL4 mRNA
CTD
PMID:17211630
NCBI chr 8:19,539,593...19,545,608
Ensembl chr 8:19,539,593...19,545,608
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Msrb1
methionine sulfoxide reductase B1
increases expression
ISO
cupric chloride results in increased expression of MSRB1 mRNA
CTD
PMID:17211630
NCBI chr10:13,764,883...13,770,609
Ensembl chr10:13,764,883...13,770,609
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Mt1
metallothionein 1
increases expression
EXP ISO
cupric chloride results in increased expression of MT1A mRNA
CTD
PMID:17211630 PMID:23174565
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
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Mt1-ps3
metallothionein 1, pseudogene 3
increases expression multiple interactions
ISO
cupric chloride results in increased expression of MT1G mRNA cupric chloride promotes the reaction [Disulfiram results in increased expression of MT1G mRNA]
CTD
PMID:19789329 PMID:32870474
NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135
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Mt2A
metallothionein 2A
multiple interactions increases expression affects expression
ISO EXP
cupric chloride promotes the reaction [Disulfiram results in increased expression of MT2A mRNA] cupric chloride results in increased expression of MT2A mRNA cupric chloride affects the expression of MT2A mRNA
CTD
PMID:17211630 PMID:17409708 PMID:19789329 PMID:20945374 PMID:23174565
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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Mtor
mechanistic target of rapamycin kinase
increases phosphorylation
ISO
cupric chloride results in increased phosphorylation of MTOR protein
CTD
PMID:32512069
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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Mvd
mevalonate diphosphate decarboxylase
decreases expression
ISO
cupric chloride results in decreased expression of MVD mRNA
CTD
PMID:34921933
NCBI chr19:50,496,366...50,506,389
Ensembl chr19:50,496,367...50,507,971
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Ncf2
neutrophil cytosolic factor 2
increases expression
ISO
cupric chloride results in increased expression of NCF2 mRNA
CTD
PMID:17211630
NCBI chr13:64,955,502...64,986,289
Ensembl chr13:64,955,503...64,986,277
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Ndufs1
NADH:ubiquinone oxidoreductase core subunit S1
decreases expression
ISO
cupric chloride results in decreased expression of NDUFS1 protein
CTD
PMID:29617964
NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893
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Ndufs4
NADH:ubiquinone oxidoreductase subunit S4
decreases expression
ISO
cupric chloride results in decreased expression of NDUFS4 protein
CTD
PMID:29617964
NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846
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Ndufv1
NADH:ubiquinone oxidoreductase core subunit V1
decreases expression
ISO
cupric chloride results in decreased expression of NDUFV1 protein
CTD
PMID:29617964
NCBI chr 1:201,300,365...201,305,461
Ensembl chr 1:201,299,985...201,305,466
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Ndufv3
NADH:ubiquinone oxidoreductase subunit V3
decreases expression
ISO
cupric chloride results in decreased expression of NDUFV3 protein
CTD
PMID:29617964
NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074
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Nefl
neurofilament light chain
decreases expression
ISO
cupric chloride results in decreased expression of NEFL protein
CTD
PMID:29617964
NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
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Neu1
neuraminidase 1
decreases expression
ISO
cupric chloride results in decreased expression of NEU1 mRNA
CTD
PMID:34921933
NCBI chr20:3,897,480...3,901,745
Ensembl chr20:3,897,480...3,901,745
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Nfix
nuclear factor I X
decreases expression
ISO
cupric chloride results in decreased expression of NFIX mRNA
CTD
PMID:17211630
NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265
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Nfkbia
NFKB inhibitor alpha
decreases expression
EXP
cupric chloride results in decreased expression of NFKBIA protein
CTD
PMID:24530511
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Nme1
NME/NM23 nucleoside diphosphate kinase 1
increases expression
ISO
cupric chloride results in increased expression of NME1 protein
CTD
PMID:29617964
NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
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Nos2
nitric oxide synthase 2
multiple interactions increases expression
ISO EXP
cupric chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]] cupric chloride results in increased expression of NOS2 protein
CTD
PMID:8975779 PMID:23313662 PMID:24170445 PMID:24530511
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Nudt5
nudix hydrolase 5
increases expression
ISO
cupric chloride results in increased expression of NUDT5 mRNA
CTD
PMID:34921933
NCBI chr17:72,435,690...72,459,008
Ensembl chr17:72,435,697...72,459,001
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Nup107
nucleoporin 107
increases expression
ISO
cupric chloride results in increased expression of NUP107 mRNA
CTD
PMID:17211630
NCBI chr 7:53,353,740...53,398,345
Ensembl chr 7:53,353,743...53,398,370
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P2rx2
purinergic receptor P2X 2
multiple interactions
EXP
cupric chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]
CTD
PMID:16190872
NCBI chr12:46,338,979...46,342,891
Ensembl chr12:46,339,549...46,342,891
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P3h4
prolyl 3-hydroxylase family member 4
affects expression
ISO
cupric chloride affects the expression of P3H4 mRNA
CTD
PMID:17211630
NCBI chr10:85,338,158...85,345,108
Ensembl chr10:85,338,161...85,345,093
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Palld
palladin, cytoskeletal associated protein
increases expression
ISO
cupric chloride results in increased expression of PALLD mRNA
CTD
PMID:17211630
NCBI chr16:28,228,006...28,621,349
Ensembl chr16:27,981,354...28,621,337
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Paqr8
progestin and adipoQ receptor family member 8
decreases expression
ISO
cupric chloride results in decreased expression of PAQR8 mRNA
CTD
PMID:17211630
NCBI chr 9:23,312,521...23,362,175
Ensembl chr 9:23,312,585...23,362,340
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Parp1
poly (ADP-ribose) polymerase 1
multiple interactions increases expression
ISO
[Disulfiram co-treated with cupric chloride] results in increased cleavage of PARP1 protein; [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased cleavage of PARP1 protein cupric chloride results in increased expression of PARP1 protein
CTD
PMID:19789329 PMID:21035945 PMID:23313662
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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Pcm1
pericentriolar material 1
decreases expression
ISO
cupric chloride results in decreased expression of PCM1 mRNA
CTD
PMID:17211630
NCBI chr16:51,008,315...51,105,261
Ensembl chr16:51,008,315...51,105,091
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Pcyt2
phosphate cytidylyltransferase 2, ethanolamine
decreases expression
ISO
cupric chloride results in decreased expression of PCYT2 mRNA
CTD
PMID:34921933
NCBI chr10:105,888,769...105,896,182
Ensembl chr10:105,888,775...105,896,172
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Pdia3
protein disulfide isomerase family A, member 3
decreases expression
ISO
cupric chloride results in decreased expression of PDIA3 protein
CTD
PMID:29617964
NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
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Pdzk1
PDZ domain containing 1
decreases expression
ISO
cupric chloride results in decreased expression of PDZK1 mRNA
CTD
PMID:17211630
NCBI chr 2:184,376,161...184,407,514
Ensembl chr 2:184,376,161...184,407,514
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Peg10
paternally expressed 10
decreases expression
ISO
cupric chloride results in decreased expression of PEG10 mRNA
CTD
PMID:17211630
NCBI chr 4:32,842,394...32,855,641
Ensembl chr 4:32,848,493...32,852,621
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Pfkp
phosphofructokinase, platelet
increases expression decreases expression
ISO
cupric chloride results in increased expression of PFKP mRNA cupric chloride results in decreased expression of PFKP mRNA
CTD
PMID:34921933
NCBI chr17:63,729,743...63,794,021
Ensembl chr17:63,729,780...63,794,018
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Pgam1
phosphoglycerate mutase 1
increases expression
ISO
cupric chloride results in increased expression of PGAM1 protein
CTD
PMID:29617964
NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
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Pgr
progesterone receptor
multiple interactions increases expression
ISO
cupric chloride promotes the reaction [Estradiol results in increased expression of PGR mRNA]; cupric chloride promotes the reaction [Estradiol results in increased expression of PGR protein]; Estradiol promotes the reaction [cupric chloride results in increased expression of PGR mRNA]; Estradiol promotes the reaction [cupric chloride results in increased expression of PGR protein]; fulvestrant inhibits the reaction [cupric chloride results in increased expression of PGR mRNA]; fulvestrant inhibits the reaction [cupric chloride results in increased expression of PGR protein] cupric chloride results in increased expression of PGR mRNA; cupric chloride results in increased expression of PGR protein
CTD
PMID:12746304
NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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Phyhip
phytanoyl-CoA 2-hydroxylase interacting protein
decreases expression
ISO
cupric chloride results in decreased expression of PHYHIP mRNA
CTD
PMID:17211630
NCBI chr15:45,533,974...45,545,223
Ensembl chr15:45,533,974...45,545,221
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Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
decreases expression
ISO
cupric chloride results in decreased expression of PITPNC1 mRNA
CTD
PMID:17211630
NCBI chr10:92,163,558...92,428,971
Ensembl chr10:92,167,196...92,429,297
G
Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
increases expression multiple interactions
ISO
cupric chloride results in increased expression of PMAIP1 mRNA [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased expression of PMAIP1 protein
CTD
PMID:20713136 PMID:21035945
NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
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Pomp
proteasome maturation protein
increases expression
ISO
cupric chloride results in increased expression of POMP mRNA
CTD
PMID:17211630
NCBI chr12:7,162,098...7,174,737
Ensembl chr12:7,160,714...7,174,715
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Prdx1
peroxiredoxin 1
increases expression
ISO
cupric chloride results in increased expression of PRDX1 mRNA
CTD
PMID:17211630
NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856
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Prdx3
peroxiredoxin 3
decreases expression
ISO
cupric chloride results in decreased expression of PRDX3 protein
CTD
PMID:29617964
NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
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Prnp
prion protein
multiple interactions increases expression
ISO EXP
[NADP co-treated with cupric chloride] promotes the reaction [PRNP protein binds to PRNP protein] cupric chloride results in increased expression of PRNP mRNA; cupric chloride results in increased expression of PRNP protein bathocuproine sulfonate inhibits the reaction [cupric chloride results in increased expression of PRNP protein]
CTD
PMID:16148034 PMID:16990274
NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
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Proc
protein C, inactivator of coagulation factors Va and VIIIa
multiple interactions
ISO
ALB protein inhibits the reaction [cupric chloride results in decreased activity of PROC protein]; aspartyl-alanyl-histidyl-lysine inhibits the reaction [cupric chloride results in decreased activity of PROC protein]; cupric chloride binds to and results in decreased activity of PROC protein
CTD
PMID:11820775
NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
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Psmb2
proteasome 20S subunit beta 2
increases expression
ISO
cupric chloride results in increased expression of PSMB2 mRNA
CTD
PMID:17211630
NCBI chr 5:138,970,564...139,002,715
Ensembl chr 5:138,970,533...139,021,137
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Psmb3
proteasome 20S subunit beta 3
increases expression
ISO
cupric chloride results in increased expression of PSMB3 mRNA
CTD
PMID:17211630
NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521
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Psmb7
proteasome 20S subunit beta 7
increases expression
ISO
cupric chloride results in increased expression of PSMB7 mRNA
CTD
PMID:17211630
NCBI chr 3:22,357,777...22,417,748
Ensembl chr 3:22,354,698...22,417,937
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Psmc1
proteasome 26S subunit, ATPase 1
increases expression
ISO
cupric chloride results in increased expression of PSMC1 mRNA
CTD
PMID:17211630
NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123
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Psmc4
proteasome 26S subunit, ATPase 4
increases expression
ISO
cupric chloride results in increased expression of PSMC4 mRNA
CTD
PMID:17211630
NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494
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Psmd1
proteasome 26S subunit, non-ATPase 1
increases expression
ISO
cupric chloride results in increased expression of PSMD1 mRNA
CTD
PMID:17211630
NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211
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Psmd11
proteasome 26S subunit, non-ATPase 11
increases expression
ISO
cupric chloride results in increased expression of PSMD11 mRNA
CTD
PMID:17211630
NCBI chr10:65,433,853...65,479,774
Ensembl chr10:65,433,853...65,479,766
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Psmd13
proteasome 26S subunit, non-ATPase 13
increases expression
ISO
cupric chloride results in increased expression of PSMD13 mRNA
CTD
PMID:17211630
NCBI chr 1:195,964,617...195,976,895
Ensembl chr 1:195,964,138...195,976,905
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Psmd14
proteasome 26S subunit, non-ATPase 14
increases expression
ISO
cupric chloride results in increased expression of PSMD14 mRNA
CTD
PMID:17211630
NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076
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Psmd2
proteasome 26S subunit ubiquitin receptor, non-ATPase 2
increases expression
ISO
cupric chloride results in increased expression of PSMD2 mRNA
CTD
PMID:17211630
NCBI chr11:80,248,364...80,258,991
Ensembl chr11:80,248,364...80,259,043
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Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression
ISO
cupric chloride results in increased expression of PTGS2 protein
CTD
PMID:23313662 PMID:24170445
NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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Ptpro
protein tyrosine phosphatase, receptor type, O
decreases expression
ISO
cupric chloride results in decreased expression of PTPRO mRNA
CTD
PMID:17211630
NCBI chr 4:170,164,071...170,374,790
Ensembl chr 4:170,164,431...170,374,771
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Pura
purine rich element binding protein A
decreases expression
ISO
cupric chloride results in decreased expression of PURA protein
CTD
PMID:29617964
NCBI chr18:27,884,618...27,905,500
Ensembl chr18:27,884,556...27,905,513
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Qki
QKI, KH domain containing RNA binding
increases expression
ISO
cupric chloride results in increased expression of QKI mRNA
CTD
PMID:17211630
NCBI chr 1:50,387,698...50,501,568
Ensembl chr 1:50,387,698...50,498,831
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Ralgapa1
Ral GTPase activating protein catalytic subunit alpha 1
affects expression
ISO
cupric chloride affects the expression of RALGAPA1 mRNA
CTD
PMID:17211630
NCBI chr 6:72,977,432...73,252,378
Ensembl chr 6:72,977,432...73,252,378
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Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
EXP
cupric chloride results in increased phosphorylation of and affects the localization of RELA protein
CTD
PMID:24530511
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Rhob
ras homolog family member B
decreases expression
ISO
cupric chloride results in decreased expression of ARHB mRNA
CTD
PMID:17211630
NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
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Rnf181
ring finger protein 181
affects expression
ISO
cupric chloride affects the expression of RNF181 mRNA
CTD
PMID:17211630
NCBI chr 4:104,414,586...104,421,433
Ensembl chr 4:104,414,605...104,421,309
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Rpl32
ribosomal protein L32
affects expression
ISO
cupric chloride affects the expression of RPL32 mRNA
CTD
PMID:17211630
NCBI chr 4:148,864,048...148,867,612
Ensembl chr 4:148,864,044...148,867,612
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Rps6kb1
ribosomal protein S6 kinase B1
increases phosphorylation
ISO
cupric chloride results in increased phosphorylation of RPS6KB1 protein
CTD
PMID:32512069
NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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Rrad
RRAD, Ras related glycolysis inhibitor and calcium channel regulator
increases expression
ISO
cupric chloride results in increased expression of RRAD mRNA
CTD
PMID:17211630
NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417
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RT1-A2
RT1 class Ia, locus A2
increases expression
ISO
cupric chloride results in increased expression of H2-D1 mRNA
CTD
PMID:17211630
NCBI chr20:4,870,939...4,910,183
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Rybp
RING1 and YY1 binding protein
affects expression
ISO
cupric chloride affects the expression of RYBP mRNA
CTD
PMID:17211630
NCBI chr 4:132,876,361...132,927,580 NCBI chr 4:132,876,260...132,929,075
Ensembl chr 4:132,876,361...132,928,316
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Sbds
Sbds, ribosome maturation factor
increases expression
ISO
cupric chloride results in increased expression of SBDS mRNA
CTD
PMID:17211630
NCBI chr12:26,420,410...26,429,650
Ensembl chr12:26,420,414...26,429,649
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Scd
stearoyl-CoA desaturase
decreases expression
ISO
cupric chloride results in decreased expression of SCD mRNA
CTD
PMID:34921933
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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Sdf2
stromal cell derived factor 2
increases expression
ISO
cupric chloride results in increased expression of SDF2 mRNA
CTD
PMID:17211630
NCBI chr10:63,140,563...63,151,038
Ensembl chr10:63,140,563...63,201,109
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Selenok
selenoprotein K
increases expression
ISO
cupric chloride results in increased expression of SELENOK mRNA
CTD
PMID:17211630
NCBI chr16:5,152,066...5,160,648
Ensembl chr16:5,152,066...5,159,188
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Selenop
selenoprotein P
decreases expression
ISO
cupric chloride results in decreased expression of SELENOP mRNA
CTD
PMID:17211630
NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852
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Septin4
septin 4
decreases expression
ISO
cupric chloride results in decreased expression of SEPTIN4 protein
CTD
PMID:29617964
NCBI chr10:72,366,729...72,390,764
Ensembl chr10:72,366,873...72,390,768
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Septin8
septin 8
decreases expression
ISO
cupric chloride results in decreased expression of SEPTIN8 protein
CTD
PMID:29617964
NCBI chr10:37,684,639...37,713,704
Ensembl chr10:37,684,639...37,713,174
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Serpinf1
serpin family F member 1
increases expression
ISO
cupric chloride results in increased expression of SERPINF1 mRNA
CTD
PMID:17211630
NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
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Shank2
SH3 and multiple ankyrin repeat domains 2
multiple interactions
EXP
[COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK2 protein
CTD
PMID:25007851
NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394
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Shank3
SH3 and multiple ankyrin repeat domains 3
multiple interactions
EXP
[COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein
CTD
PMID:25007851
NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374
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Sirt7
sirtuin 7
increases expression
ISO
cupric chloride results in increased expression of SIRT7 mRNA
CTD
PMID:17211630
NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172
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Slc11a2
solute carrier family 11 member 2
multiple interactions
ISO
cupric chloride inhibits the reaction [SLC11A2 protein results in increased uptake of Iron]
CTD
PMID:12220667
NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
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Slc13a3
solute carrier family 13 member 3
decreases expression
ISO
cupric chloride results in decreased expression of SLC13A3 mRNA
CTD
PMID:17211630
NCBI chr 3:154,141,878...154,204,604
Ensembl chr 3:154,141,872...154,204,606
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Slc22a18
solute carrier family 22, member 18
increases expression
ISO
cupric chloride results in increased expression of SLC22A18 mRNA
CTD
PMID:17211630
NCBI chr 1:198,670,626...198,694,977
Ensembl chr 1:198,671,731...198,694,975
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Slc2a1
solute carrier family 2 member 1
increases expression
ISO
cupric chloride results in increased expression of SLC2A1 mRNA
CTD
PMID:15741220
NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
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Slc30a1
solute carrier family 30 member 1
increases expression
ISO
cupric chloride results in increased expression of SLC30A1 mRNA
CTD
PMID:24343273
NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
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Slc31a1
solute carrier family 31 member 1
decreases expression multiple interactions
EXP ISO
cupric chloride results in decreased expression of SLC31A1 protein SLC31A1 protein results in increased susceptibility to [cupric chloride results in increased abundance of Copper]
CTD
PMID:24316150 PMID:24800945 PMID:32278528
NCBI chr 5:75,814,744...75,844,241
Ensembl chr 5:75,814,743...75,844,228
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Snca
synuclein alpha
affects folding
ISO
cupric chloride affects the folding of SNCA protein
CTD
PMID:11553618
NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
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Sod1
superoxide dismutase 1
multiple interactions increases response to substance decreases expression decreases activity
ISO
Carnosine inhibits the reaction [cupric chloride results in decreased activity of SOD1 protein]; cupric chloride promotes the reaction [COMMD1 protein binds to SOD1 protein]; Pyruvic Acid inhibits the reaction [SOD1 protein mutant form promotes the reaction [cupric chloride results in increased abundance of Peroxides]]; Pyruvic Acid inhibits the reaction [SOD1 protein mutant form results in increased susceptibility to cupric chloride]; SOD1 protein mutant form promotes the reaction [cupric chloride results in increased abundance of Peroxides] cupric chloride results in decreased expression of SOD1 protein
CTD
PMID:15812313 PMID:24691167 PMID:29617964 PMID:32745495
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Sorbs1
sorbin and SH3 domain containing 1
decreases expression
ISO
cupric chloride results in decreased expression of SORBS1 mRNA
CTD
PMID:17211630
NCBI chr 1:239,107,882...239,330,276
Ensembl chr 1:239,108,777...239,330,169
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Spsb1
splA/ryanodine receptor domain and SOCS box containing 1
increases expression
ISO
cupric chloride results in increased expression of SPSB1 mRNA
CTD
PMID:17211630
NCBI chr 5:160,358,292...160,418,541
Ensembl chr 5:160,358,308...160,418,468
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Sqle
squalene epoxidase
decreases expression
ISO
cupric chloride results in decreased expression of SQLE mRNA
CTD
PMID:34921933
NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
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Sqstm1
sequestosome 1
increases expression multiple interactions
ISO
cupric chloride results in increased expression of SQSTM1 mRNA cupric chloride results in increased expression of SQSTM1 protein Acetylcysteine inhibits the reaction [cupric chloride results in increased expression of SQSTM1 protein]; PP242 inhibits the reaction [cupric chloride results in increased expression of SQSTM1 protein]
CTD
PMID:17211630 PMID:23313662 PMID:32512069
NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
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Srebf2
sterol regulatory element binding transcription factor 2
decreases expression
ISO
cupric chloride results in decreased expression of SREBF2 mRNA
CTD
PMID:34921933
NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
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St6gal1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
decreases expression
ISO
cupric chloride results in decreased expression of ST6GAL1 mRNA
CTD
PMID:17211630
NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
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Stard4
StAR-related lipid transfer domain containing 4
decreases expression
ISO
cupric chloride results in decreased expression of STARD4 mRNA
CTD
PMID:34921933
NCBI chr18:24,814,683...24,830,024
Ensembl chr18:24,817,107...24,830,024
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Stau1
staufen double-stranded RNA binding protein 1
decreases expression
ISO
cupric chloride results in decreased expression of STAU mRNA
CTD
PMID:17211630
NCBI chr 3:155,680,000...155,725,969
Ensembl chr 3:155,680,000...155,725,909
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Stmn1
stathmin 1
decreases expression
ISO
cupric chloride results in decreased expression of STMN1 protein
CTD
PMID:29617964
NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
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Syn2
synapsin II
decreases expression
ISO
cupric chloride results in decreased expression of SYN2 protein
CTD
PMID:29617964
NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192
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Taf7l
TATA-box binding protein associated factor 7-like
increases expression
ISO
cupric chloride results in increased expression of TAF7L mRNA
CTD
PMID:17211630
NCBI chr X:97,660,222...97,675,241
Ensembl chr X:97,660,222...97,675,023
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Taldo1
transaldolase 1
increases expression
ISO
cupric chloride results in increased expression of TALDO1 mRNA
CTD
PMID:17211630
NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974
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Tardbp
TAR DNA binding protein
multiple interactions
ISO
cupric chloride inhibits the reaction [Paraquat affects the localization of TARDBP protein]
CTD
PMID:22879928
NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055
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Tfdp2
transcription factor Dp-2
affects expression
ISO
cupric chloride affects the expression of TFDP2 mRNA
CTD
PMID:17211630
NCBI chr 8:96,760,459...96,901,466
Ensembl chr 8:96,760,504...96,896,682
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Tfeb
transcription factor EB
decreases expression multiple interactions
ISO
cupric chloride results in decreased expression of TFEB mRNA; cupric chloride results in decreased expression of TFEB protein PP242 inhibits the reaction [cupric chloride results in decreased expression of TFEB protein]
CTD
PMID:32512069
NCBI chr 9:13,198,890...13,254,726
Ensembl chr 9:13,198,891...13,254,714
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Tkt
transketolase
increases expression
ISO
cupric chloride results in increased expression of TKT mRNA
CTD
PMID:17211630
NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
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Tmed2
transmembrane p24 trafficking protein 2
decreases expression
ISO
cupric chloride results in decreased expression of TMED2 mRNA
CTD
PMID:17211630
NCBI chr12:32,052,542...32,061,596
Ensembl chr12:32,052,543...32,071,903
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Tmem97
transmembrane protein 97
decreases expression
ISO
cupric chloride results in decreased expression of TMEM97 mRNA
CTD
PMID:34921933
NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730
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Tnf
tumor necrosis factor
increases secretion increases expression multiple interactions
ISO EXP
cupric chloride results in increased secretion of TNF protein cupric chloride results in increased expression of TNF protein cupric chloride inhibits the reaction [TNF protein results in increased secretion of IL6 protein] 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [cupric chloride results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [cupric chloride results in increased secretion of TNF protein]; SC 514 inhibits the reaction [cupric chloride results in increased secretion of TNF protein]
CTD
PMID:22954531 PMID:23285694 PMID:23313662 PMID:24170445 PMID:24530511
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tp53
tumor protein p53
affects expression increases expression decreases expression multiple interactions
ISO
cupric chloride affects the expression of TRP53 mRNA cupric chloride results in increased expression of TRP53 protein cupric chloride results in decreased expression of TRP53 protein [cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; Ethanol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; neocuproine inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; Thiourea inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]
CTD
PMID:23313662 PMID:24170445 PMID:29803612
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Tp73
tumor protein p73
affects expression increases expression
ISO
cupric chloride affects the expression of TRP73 protein cupric chloride results in increased expression of TRP73 protein
CTD
PMID:23313662 PMID:24170445
NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
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Tpm1
tropomyosin 1
increases expression
ISO
cupric chloride results in increased expression of TPM1 protein
CTD
PMID:29617964
NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
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Tppp
tubulin polymerization promoting protein
increases expression
ISO
cupric chloride results in increased expression of TPPP protein
CTD
PMID:29617964
NCBI chr 1:29,257,111...29,281,134
Ensembl chr 1:29,261,255...29,281,134
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Traf5
TNF receptor-associated factor 5
increases expression
ISO
cupric chloride results in increased expression of TRAF5 mRNA
CTD
PMID:17211630
NCBI chr13:103,569,944...103,618,756
Ensembl chr13:103,572,314...103,618,709
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Trib3
tribbles pseudokinase 3
increases expression
ISO
cupric chloride results in increased expression of TRIB3 mRNA
CTD
PMID:17211630
NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
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Tsc22d3
TSC22 domain family, member 3
multiple interactions
ISO
[cupric chloride results in increased abundance of Copper] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]
CTD
PMID:29957541
NCBI chr X:104,217,898...104,277,935
Ensembl chr X:104,217,925...104,276,861
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Txn1
thioredoxin 1
increases expression
ISO
cupric chloride results in increased expression of TXN mRNA
CTD
PMID:17211630
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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Txnl1
thioredoxin-like 1
increases expression
ISO
cupric chloride results in increased expression of TXNL1 mRNA
CTD
PMID:17211630
NCBI chr18:57,125,362...57,155,167
Ensembl chr18:57,125,369...57,165,266
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Txnrd1
thioredoxin reductase 1
increases expression
ISO
cupric chloride results in increased expression of TXNRD1 mRNA
CTD
PMID:17211630
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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Tyr
tyrosinase
multiple interactions
ISO
cupric chloride inhibits the reaction [bathocuproine sulfonate inhibits the reaction [ATP7A protein results in increased activity of TYR protein]]
CTD
PMID:11092760
NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
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Uba1
ubiquitin-like modifier activating enzyme 1
multiple interactions
ISO
cupric chloride promotes the reaction [Dimethyldithiocarbamate results in decreased activity of and results in decreased ubiquitination of UBA1 protein]; cupric chloride results in decreased activity of and results in decreased ubiquitination of UBA1 protein
CTD
PMID:25714994
NCBI chr X:1,508,700...1,530,677
Ensembl chr X:1,508,666...1,530,636
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Ubc
ubiquitin C
increases expression
ISO
cupric chloride results in increased expression of UBC mRNA
CTD
PMID:17211630
NCBI chr12:31,238,889...31,243,924
Ensembl chr12:31,239,152...31,243,925
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Ubr5
ubiquitin protein ligase E3 component n-recognin 5
increases expression
ISO
cupric chloride results in increased expression of UBR5 mRNA
CTD
PMID:17211630
NCBI chr 7:69,116,758...69,224,490
Ensembl chr 7:69,116,761...69,224,903
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Uchl1
ubiquitin C-terminal hydrolase L1
increases expression
ISO
cupric chloride results in increased expression of UCHL1 protein
CTD
PMID:29617964
NCBI chr14:41,485,033...41,495,590
Ensembl chr14:41,485,031...41,495,590
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Ufd1
ubiquitin recognition factor in ER associated degradation 1
increases expression
ISO
cupric chloride results in increased expression of UFD1 mRNA
CTD
PMID:17211630
NCBI chr11:82,161,618...82,185,107
Ensembl chr11:82,161,619...82,185,087
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Unc79
unc-79 homolog, NALCN channel complex subunit
decreases expression
ISO
cupric chloride results in decreased expression of UNC79 mRNA
CTD
PMID:34921933
NCBI chr 6:122,082,369...122,327,641
Ensembl chr 6:122,080,308...122,327,591
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Unkl
unk like zinc finger
increases expression
ISO
cupric chloride results in increased expression of UNKL mRNA
CTD
PMID:17211630
NCBI chr10:14,206,125...14,252,226
Ensembl chr10:14,206,189...14,252,225
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Uqcrc1
ubiquinol-cytochrome c reductase core protein 1
increases expression
ISO
cupric chloride results in increased expression of UQCRC1 protein
CTD
PMID:29617964
NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480
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Uqcrh
ubiquinol-cytochrome c reductase hinge protein
decreases expression
ISO
cupric chloride results in decreased expression of UQCRH protein
CTD
PMID:29617964
NCBI chr 5:129,545,978...129,554,173
Ensembl chr 5:129,545,984...129,554,242
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Utp11
UTP11, small subunit processome component
increases expression
ISO
cupric chloride results in increased expression of UTP11 mRNA
CTD
PMID:17211630
NCBI chr 5:136,931,279...136,946,164
Ensembl chr 5:136,931,008...136,946,191
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Vdac1
voltage-dependent anion channel 1
increases expression
ISO
cupric chloride results in increased expression of VDAC1 protein
CTD
PMID:29617964
NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
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Vdac2
voltage-dependent anion channel 2
increases expression
ISO
cupric chloride results in increased expression of VDAC2 protein
CTD
PMID:29617964
NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
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Vegfa
vascular endothelial growth factor A
increases expression
ISO
cupric chloride results in increased expression of VEGFA mRNA
CTD
PMID:15741220
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
G
Vps13b
vacuolar protein sorting 13 homolog B
affects expression
ISO
cupric chloride affects the expression of VPS13B mRNA
CTD
PMID:17211630
NCBI chr 7:66,557,862...67,128,429
Ensembl chr 7:66,558,471...67,128,429
G
Wdr74
WD repeat domain 74
affects expression
ISO
cupric chloride affects the expression of WDR74 mRNA
CTD
PMID:17211630
NCBI chr 1:205,631,769...205,636,563
Ensembl chr 1:205,631,824...205,636,563
G
Zbtb5
zinc finger and BTB domain containing 5
decreases expression
ISO
cupric chloride results in decreased expression of ZBTB5 mRNA
CTD
PMID:34921933
NCBI chr 5:59,244,132...59,265,461
Ensembl chr 5:59,243,307...59,265,426
G
Zfp12
zinc finger protein 12
increases expression
ISO
cupric chloride results in increased expression of ZNF12 mRNA
CTD
PMID:17211630
NCBI chr12:11,316,971...11,330,498
Ensembl chr12:11,316,872...11,330,558
G
Znrd2
zinc ribbon domain containing 2
increases expression
ISO
cupric chloride results in increased expression of ZNRD2 mRNA
CTD
PMID:17211630
NCBI chr 1:203,017,682...203,019,465
Ensembl chr 1:203,017,682...203,019,465
G
Zswim6
zinc finger, SWIM-type containing 6
affects expression
ISO
cupric chloride affects the expression of ZSWIM6 mRNA
CTD
PMID:17211630
NCBI chr 2:39,211,131...39,378,877
Ensembl chr 2:39,212,949...39,378,924
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