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Accession:CHEBI:49537 term browser browse the term
Definition:A cyclic purine dinucleotide that is the 3',5'-cyclic dimer of MP.
Synonyms:exact_synonym: 9,9'-[(2R,3R,3aS,7aR,9R,10R,10aS,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one)
 related_synonym: 3',5'-Cyclic diguanylic acid;   3',5'-cyclic di-GMP;   Bis-(3',5')-cyclic diGMP;   Cyclic di-3',5'-guanylate;   Formula=C20H24N10O14P2;   InChI=1S/C20H24N10O14P2/c21-19-25-13-7(15(33)27-19)23-3-29(13)17-9(31)11-5(41-17)1-39-45(35,36)44-12-6(2-40-46(37,38)43-11)42-18(10(12)32)30-4-24-8-14(30)26-20(22)28-16(8)34/h3-6,9-12,17-18,31-32H,1-2H2,(H,35,36)(H,37,38)(H3,21,25,27,33)(H3,22,26,28,34)/t5-,6-,9-,10-,11-,12-,17-,18-/m1/s1;   InChIKey=PKFDLKSEZWEFGL-MHARETSRSA-N;   SMILES=Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(O)(=O)O[C@@H]3[C@@H](COP(O)(=O)O[C@H]2[C@H]1O)O[C@H]([C@@H]3O)n1cnc2c1nc(N)[nH]c2=O;   bis-(3'-5')-cyclic dimeric guanosine monophosphate;   c-(GpGp);   cGpGp;   cdiGMP;   cyclic di-3',5'-guanylic acid;   cyclic di-GMP;   cyclic diguanylic acid;   cyclic dinucleotide di-GMP;   cyclic-bis(3',5')diguanylic acid;   cyclic-bis(3'->5') dimeric GMP;   guanylyl-(3'->5')-3'-guanylic acid, cyclic 3'->5'''-nucleotide
 alt_id: CHEBI:47036;   CHEBI:49535
 xref: Beilstein:9696190;   CAS:61093-23-0;   KEGG:C16463
 xref_mesh: MESH:C062025
 xref: MetaCyc:C-DI-GMP;   PMID:17646358;   PMID:19691499;   PMID:20577685;   PMID:21320509;   PMID:22021215;   PMID:22661686;   PMID:22728658;   PMID:22728659;   PMID:22728660;   PMID:22821967;   PMID:23021863;   PMID:23023210;   PMID:23202856;   PMID:23289502;   PMID:23299943;   Reaxys:9606190
 cyclic_relationship: is_conjugate_acid_of CHEBI:58805

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c-di-GMP term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tdrd7 tudor domain containing 7 JBrowse link 5 61,557,909 61,631,719 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19779
    role 19727
      biological role 19726
        immunomodulator 13696
          c-di-GMP 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19779
    subatomic particle 19777
      composite particle 19777
        hadron 19777
          baryon 19777
            nucleon 19777
              atomic nucleus 19777
                atom 19777
                  main group element atom 19664
                    p-block element atom 19664
                      chalcogen 19366
                        oxygen atom 19327
                          oxygen molecular entity 19327
                            hydroxides 19071
                              oxoacid 18165
                                pnictogen oxoacid 10138
                                  phosphorus oxoacid 9040
                                    phosphoric acids 7796
                                      phosphoric acid 7796
                                        phosphoric acid derivative 7472
                                          phosphate 7472
                                            organic phosphate 7471
                                              carbohydrate phosphate 1530
                                                phospho sugar 1456
                                                  aldose phosphate 1454
                                                    aldopentose phosphate 1448
                                                      ribose phosphate 1442
                                                        ribonucleotide 1401
                                                          purine ribonucleotide 1374
                                                            guanyl ribonucleotide 129
                                                              c-di-GMP 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.