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G |
Gna15 |
G protein subunit alpha 15 |
increases response to substance multiple interactions |
ISO |
GNA15 protein results in increased susceptibility to alpha-ionone [GNA15 protein results in increased susceptibility to alpha-ionone] which results in increased activity of OLFR43 protein |
CTD |
PMID:15598656 |
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NCBI chr 7:11,054,249...11,075,152
Ensembl chr 7:11,054,333...11,077,251
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G |
Olr1513 |
olfactory receptor 1513 |
multiple interactions |
ISO |
[GNA15 protein results in increased susceptibility to alpha-ionone] which results in increased activity of OLFR43 protein |
CTD |
PMID:15598656 |
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NCBI chr10:61,033,113...61,034,051
Ensembl chr10:61,033,113...61,034,051
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G |
Olr59 |
olfactory receptor 59 |
decreases activity |
ISO |
alpha-ionone results in decreased activity of OR51E2 protein |
CTD |
PMID:27226631 |
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NCBI chr 1:167,906,030...167,940,688
Ensembl chr 1:167,906,061...167,911,961
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression |
ISO |
beta-ionone results in increased expression of BAX protein |
CTD |
PMID:31506784 |
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NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression |
ISO |
beta-ionone results in decreased expression of BCL2 protein |
CTD |
PMID:23100158 PMID:31506784 |
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NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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G |
Casp3 |
caspase 3 |
multiple interactions increases cleavage increases expression |
ISO |
[alpha-Tocopherol co-treated with beta-ionone] results in increased activity of CASP3 protein beta-ionone results in increased cleavage of CASP3 protein beta-ionone results in increased expression of CASP3 protein modified form |
CTD |
PMID:17618090 PMID:23100158 PMID:31506784 |
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NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
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G |
Ccnd1 |
cyclin D1 |
decreases expression |
ISO |
beta-ionone results in decreased expression of CCND1 protein |
CTD |
PMID:15450939 PMID:31506784 |
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NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
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G |
Cdk2 |
cyclin dependent kinase 2 |
decreases expression |
ISO |
beta-ionone results in decreased expression of CDK2 protein |
CTD |
PMID:15450939 |
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NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
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G |
Cdk4 |
cyclin-dependent kinase 4 |
decreases expression |
ISO |
beta-ionone results in decreased expression of CDK4 protein |
CTD |
PMID:15450939 PMID:31506784 |
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NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
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G |
Cryz |
crystallin zeta |
increases activity |
ISO |
beta-ionone results in increased activity of CRYZ protein |
CTD |
PMID:31506784 |
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NCBI chr 2:260,884,315...260,911,827
Ensembl chr 2:260,884,337...260,911,792
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
multiple interactions |
EXP |
beta-ionone promotes the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of HMGCR mRNA] |
CTD |
PMID:20435455 |
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NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
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G |
Lmnb1 |
lamin B1 |
decreases farnesylation |
ISO |
beta-ionone results in decreased farnesylation of LMNB1 protein |
CTD |
PMID:10203554 |
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NCBI chr18:51,785,111...51,822,264
Ensembl chr18:51,785,111...51,822,264
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G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation multiple interactions |
ISO |
beta-ionone results in increased phosphorylation of MAPK1 protein beta-ionone inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK1 protein modified form] |
CTD |
PMID:23268108 PMID:27226631 |
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NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO |
beta-ionone inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK3 protein modified form] beta-ionone results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:23268108 PMID:27226631 |
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NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO |
beta-ionone inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein] |
CTD |
PMID:23268108 |
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NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
beta-ionone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; beta-ionone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] |
CTD |
PMID:23268108 |
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NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
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G |
Olr59 |
olfactory receptor 59 |
multiple interactions |
ISO |
beta-ionone binds to and results in increased activity of OR51E2 protein |
CTD |
PMID:27226631 |
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NCBI chr 1:167,906,030...167,940,688
Ensembl chr 1:167,906,061...167,911,961
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
beta-ionone inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; beta-ionone inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] beta-ionone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] |
CTD |
PMID:23268108 PMID:31506784 |
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NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
beta-ionone inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] |
CTD |
PMID:23268108 |
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NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
beta-ionone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; beta-ionone inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] |
CTD |
PMID:23268108 |
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NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
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G |
Tyr |
tyrosinase |
increases expression |
ISO |
beta-ionone results in increased expression of TYR mRNA; beta-ionone results in increased expression of TYR protein |
CTD |
PMID:27226631 |
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NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802
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