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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:methylquinoline
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Accession:CHEBI:48982 term browser browse the term
Definition:Any member of the class of quinolines carrying at least one methyl substituent.
Synonyms:related_synonym: methylquinolines


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3-methylquinoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO 3-methylquinoline results in decreased activity of CYP1A2 protein CTD PMID:15916432 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Esr1 estrogen receptor 1 increases activity
multiple interactions
ISO 3-methylquinoline results in increased activity of ESR1 protein
3-methylquinoline inhibits the reaction [Estradiol binds to ESR1 protein]; Hydralazine inhibits the reaction [3-methylquinoline results in increased activity of ESR1 protein]
CTD PMID:30896932 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
4-methylquinoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 increases activity ISO 4-methylquinoline analog results in increased activity of ESR1 protein; 4-methylquinoline results in increased activity of ESR1 protein CTD PMID:30896932 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
8-methylquinoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 multiple interactions
increases activity
ISO 8-methylquinoline inhibits the reaction [Estradiol binds to ESR1 protein]; Hydralazine inhibits the reaction [8-methylquinoline results in increased activity of ESR1 protein] CTD PMID:30896932 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19791
    chemical entity 19791
      molecular entity 19788
        polyatomic entity 19701
          molecule 19525
            organic molecule 19493
              organic cyclic compound 19288
                organic aromatic compound 19122
                  quinolines 2561
                    methylquinoline 2
                      3-methylquinoline 2
                      4-methylquinoline 1
                      8-methylquinoline 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19791
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19676
                    p-block element atom 19676
                      carbon group element atom 19579
                        carbon atom 19568
                          organic molecular entity 19568
                            organic molecule 19493
                              organic cyclic compound 19288
                                organic heterocyclic compound 18407
                                  organonitrogen heterocyclic compound 17461
                                    quinolines 2561
                                      methylquinoline 2
                                        3-methylquinoline 2
                                        4-methylquinoline 1
                                        8-methylquinoline 1
paths to the root

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