CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | thiazoles |
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Accession: | CHEBI:48901
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browse the term
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Definition: | An azole in which the five-membered heterocyclic aromatic skeleton contains a N atom and one S atom. |
Synonyms: | related_synonym: | thiazole |
| alt_id: | MESH:D013844 |
| xref_mesh: | MESH:D013844 |
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Bid |
BH3 interacting domain death agonist |
multiple interactions |
ISO |
[Heterocyclic Compounds binds to Thiazoles] which results in decreased expression of BID protein |
CTD |
PMID:19014919 |
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NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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Casp3 |
caspase 3 |
multiple interactions |
ISO |
[Heterocyclic Compounds binds to Thiazoles] which results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [[Heterocyclic Compounds binds to Thiazoles] which results in increased activity of CASP3 protein] |
CTD |
PMID:19014919 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp8 |
caspase 8 |
multiple interactions |
ISO |
[Heterocyclic Compounds binds to Thiazoles] which results in increased activity of CASP8 protein; Acetylcysteine inhibits the reaction [[Heterocyclic Compounds binds to Thiazoles] which results in increased activity of CASP8 protein] |
CTD |
PMID:19014919 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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Cat |
catalase |
multiple interactions |
ISO |
CAT inhibits the reaction [[Heterocyclic Compounds binds to Thiazoles] which results in increased abundance of Reactive Oxygen Species] |
CTD |
PMID:19014919 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions |
EXP |
[Thiazoles co-treated with ciprofibrate] results in increased expression of CYP2E1 protein |
CTD |
PMID:7587954 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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Ephx1 |
epoxide hydrolase 1 |
increases expression |
EXP |
Thiazoles results in increased expression of EPHX1 mRNA |
CTD |
PMID:8951341 |
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NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
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Fas |
Fas cell surface death receptor |
multiple interactions |
ISO |
[Heterocyclic Compounds binds to Thiazoles] which results in increased expression of FAS protein; Acetylcysteine inhibits the reaction [[Heterocyclic Compounds binds to Thiazoles] which results in increased expression of FAS protein] |
CTD |
PMID:19014919 |
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NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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Gsta2 |
glutathione S-transferase alpha 2 |
increases expression |
EXP |
Thiazoles results in increased expression of GSTA2 mRNA; Thiazoles results in increased expression of GSTA2 protein |
CTD |
PMID:8951341 |
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NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
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Gsta3 |
glutathione S-transferase alpha 3 |
increases expression |
EXP |
Thiazoles results in increased expression of GSTA3 mRNA; Thiazoles results in increased expression of GSTA3 protein |
CTD |
PMID:8951341 |
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NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
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Gsta5 |
glutathione S-transferase alpha 5 |
increases expression |
EXP |
Thiazoles results in increased expression of GSTA5 mRNA |
CTD |
PMID:8951341 |
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NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
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Gstm1 |
glutathione S-transferase mu 1 |
increases expression |
EXP |
Thiazoles results in increased expression of GSTM1 mRNA; Thiazoles results in increased expression of GSTM1 protein |
CTD |
PMID:8951341 |
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NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
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Gstm2 |
glutathione S-transferase mu 2 |
increases expression |
EXP |
Thiazoles results in increased expression of GSTM2 mRNA; Thiazoles results in increased expression of GSTM2 protein |
CTD |
PMID:8951341 |
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NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
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Hsf1 |
heat shock transcription factor 1 |
increases activity |
ISO |
Thiazoles results in increased activity of HSF1 protein |
CTD |
PMID:34170685 |
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NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
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Il1b |
interleukin 1 beta |
multiple interactions |
EXP |
[Thiazoles analog binds to indoline analog] promotes the reaction [PHLDA3 protein promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of IL1B protein]] |
CTD |
PMID:34351043 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il5 |
interleukin 5 |
multiple interactions |
ISO |
Dithiothreitol inhibits the reaction [Thiazoles analog inhibits the reaction [IL5 protein binds to IL5RA protein]]; Thiazoles analog inhibits the reaction [IL5 protein binds to IL5RA protein] |
CTD |
PMID:7957178 |
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NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
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Il5ra |
interleukin 5 receptor subunit alpha |
multiple interactions |
ISO |
Dithiothreitol inhibits the reaction [Thiazoles analog inhibits the reaction [IL5 protein binds to IL5RA protein]]; Thiazoles analog inhibits the reaction [IL5 protein binds to IL5RA protein] |
CTD |
PMID:7957178 |
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NCBI chr 4:139,630,652...139,664,593
Ensembl chr 4:139,632,066...139,668,544
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Il6 |
interleukin 6 |
multiple interactions |
EXP |
[Thiazoles analog binds to indoline analog] promotes the reaction [PHLDA3 protein promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of IL6 protein]] |
CTD |
PMID:34351043 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
EXP |
[Thiazoles analog binds to indoline analog] inhibits the reaction [SESN2 protein promotes the reaction [Hydrogen Peroxide results in increased activity of NFE2L2 protein]]; [Thiazoles analog binds to indoline analog] promotes the reaction [PHLDA3 protein inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of and affects the localization of and results in increased activity of NFE2L2 protein]]; [Thiazoles analog binds to indoline analog] which results in decreased activity of NFE2L2 protein |
CTD |
PMID:32275923 PMID:34351043 |
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NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
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Phlda3 |
pleckstrin homology-like domain, family A, member 3 |
multiple interactions |
EXP |
[Thiazoles analog binds to indoline analog] promotes the reaction [PHLDA3 protein inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of and affects the localization of and results in increased activity of NFE2L2 protein]]; [Thiazoles analog binds to indoline analog] promotes the reaction [PHLDA3 protein promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of IL1B protein]]; [Thiazoles analog binds to indoline analog] promotes the reaction [PHLDA3 protein promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of IL6 protein]]; [Thiazoles analog binds to indoline analog] promotes the reaction [PHLDA3 protein promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of TNF protein]] |
CTD |
PMID:34351043 |
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NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335
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Rarg |
retinoic acid receptor, gamma |
multiple interactions |
ISO |
Thiazoles binds to and results in increased activity of RARG protein |
CTD |
PMID:17076708 |
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NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177
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Sesn2 |
sestrin 2 |
multiple interactions |
EXP |
[Thiazoles analog binds to indoline analog] inhibits the reaction [SESN2 protein promotes the reaction [Hydrogen Peroxide results in increased activity of NFE2L2 protein]] |
CTD |
PMID:32275923 |
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NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
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Slc1a5 |
solute carrier family 1 member 5 |
multiple interactions decreases activity |
EXP |
Dithioerythritol inhibits the reaction [Thiazoles analog results in decreased activity of SLC1A5 protein] |
CTD |
PMID:23010140 |
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NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952
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Tnf |
tumor necrosis factor |
multiple interactions |
EXP |
[Thiazoles analog binds to indoline analog] promotes the reaction [PHLDA3 protein promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of TNF protein]] |
CTD |
PMID:34351043 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Anxa10 |
annexin A10 |
increases expression |
ISO |
Thiamethoxam results in increased expression of ANXA10 mRNA |
CTD |
PMID:32194361 |
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NCBI chr16:27,738,712...27,805,648
Ensembl chr16:27,738,712...27,805,648
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Ar |
androgen receptor |
affects binding |
ISO |
Thiamethoxam binds to AR protein |
CTD |
PMID:31550567 |
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Arg1 |
arginase 1 |
decreases expression |
ISO |
Thiamethoxam results in decreased expression of ARG1 mRNA |
CTD |
PMID:32194361 |
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NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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Atf3 |
activating transcription factor 3 |
increases expression |
ISO |
Thiamethoxam results in increased expression of ATF3 mRNA |
CTD |
PMID:33533595 |
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NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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Bax |
BCL2 associated X, apoptosis regulator |
increases expression |
ISO |
Thiamethoxam results in increased expression of BAX protein |
CTD |
PMID:33533595 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2 |
BCL2, apoptosis regulator |
decreases expression |
ISO |
Thiamethoxam results in decreased expression of BCL2 protein |
CTD |
PMID:33533595 |
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NCBI chr13:22,689,783...22,853,920
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Bcl6 |
BCL6, transcription repressor |
decreases expression |
ISO |
Thiamethoxam results in decreased expression of BCL6 mRNA |
CTD |
PMID:33533595 |
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NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
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Btg1 |
BTG anti-proliferation factor 1 |
increases expression |
ISO |
Thiamethoxam results in increased expression of BTG1 mRNA |
CTD |
PMID:33533595 |
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NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649
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Casp3 |
caspase 3 |
increases cleavage |
ISO |
Thiamethoxam results in increased cleavage of CASP3 protein |
CTD |
PMID:33533595 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Cat |
catalase |
increases expression decreases activity multiple interactions |
ISO EXP |
Thiamethoxam results in increased expression of CAT mRNA Thiamethoxam results in decreased activity of CAT protein Plant Extracts inhibits the reaction [Thiamethoxam results in decreased activity of CAT protein] |
CTD |
PMID:33533595 PMID:34181816 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccl2 |
C-C motif chemokine ligand 2 |
increases expression |
ISO |
Thiamethoxam results in increased expression of CCL2 mRNA |
CTD |
PMID:33533595 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Chrnb2 |
cholinergic receptor nicotinic beta 2 subunit |
multiple interactions |
EXP |
Thiamethoxam results in increased activity of [NACHRA1 protein co-treated with CHRNB2 protein] |
CTD |
PMID:16981889 |
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NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
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Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
decreases expression multiple interactions |
EXP |
Thiamethoxam results in decreased expression of CYP11A1 mRNA Plant Extracts inhibits the reaction [Thiamethoxam results in decreased expression of CYP11A1 mRNA] |
CTD |
PMID:34181816 |
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NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
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Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
decreases expression multiple interactions |
EXP |
Thiamethoxam results in decreased expression of CYP17A1 mRNA Plant Extracts inhibits the reaction [Thiamethoxam results in decreased expression of CYP17A1 mRNA] |
CTD |
PMID:34181816 |
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NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
increases expression multiple interactions increases activity |
ISO EXP |
Thiamethoxam results in increased expression of CYP19A1 mRNA Plant Extracts inhibits the reaction [Thiamethoxam results in increased expression of CYP19A1 mRNA] Thiamethoxam results in increased activity of CYP19A1 protein |
CTD |
PMID:26464060 PMID:28750898 PMID:34181816 |
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NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
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Cyp2c6v1 |
cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 |
decreases expression |
ISO |
Thiamethoxam results in decreased expression of CYP2C19 protein |
CTD |
PMID:32194361 |
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NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions |
ISO |
[NADP co-treated with CYP3A4 protein] results in increased activity of Thiamethoxam |
CTD |
PMID:16153789 |
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NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
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Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
decreases expression |
ISO |
Thiamethoxam results in decreased expression of CYP7A1 protein |
CTD |
PMID:32194361 |
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NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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Ddit3 |
DNA-damage inducible transcript 3 |
increases expression |
ISO |
Thiamethoxam results in increased expression of DDIT3 mRNA; Thiamethoxam results in increased expression of DDIT3 protein |
CTD |
PMID:33533595 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Esr1 |
estrogen receptor 1 |
affects binding decreases expression |
ISO |
Thiamethoxam binds to ESR1 protein Thiamethoxam results in decreased expression of ESR1 protein |
CTD |
PMID:31550567 PMID:33533595 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Foxo3 |
forkhead box O3 |
increases expression |
ISO |
Thiamethoxam results in increased expression of FOXO3 mRNA |
CTD |
PMID:33533595 |
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NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
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Fshr |
follicle stimulating hormone receptor |
decreases expression |
ISO |
Thiamethoxam results in decreased expression of FSHR protein |
CTD |
PMID:33533595 |
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NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
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G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
decreases expression |
ISO |
Thiamethoxam results in decreased expression of G6PC1 mRNA |
CTD |
PMID:32194361 |
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NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
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Gadd45b |
growth arrest and DNA-damage-inducible, beta |
decreases expression |
ISO |
Thiamethoxam results in decreased expression of GADD45B mRNA |
CTD |
PMID:33533595 |
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NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
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Gpt |
glutamic--pyruvic transaminase |
decreases activity |
EXP |
Thiamethoxam results in decreased activity of GPT protein |
CTD |
PMID:29197058 |
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NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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Gpx1 |
glutathione peroxidase 1 |
increases expression |
ISO |
Thiamethoxam results in increased expression of GPX1 mRNA |
CTD |
PMID:33533595 |
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NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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Hsd3b1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
multiple interactions decreases expression |
EXP |
Plant Extracts inhibits the reaction [Thiamethoxam results in decreased expression of HSD3B1 mRNA] |
CTD |
PMID:34181816 |
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NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
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Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
ISO |
Thiamethoxam results in increased expression of HSPA5 mRNA; Thiamethoxam results in increased expression of HSPA5 protein |
CTD |
PMID:33533595 |
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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Itpr1 |
inositol 1,4,5-trisphosphate receptor, type 1 |
decreases expression |
ISO |
Thiamethoxam results in decreased expression of ITPR1 mRNA |
CTD |
PMID:33533595 |
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NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
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Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
decreases expression |
ISO |
Thiamethoxam results in decreased expression of JUNB mRNA |
CTD |
PMID:33533595 |
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NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
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Lhcgr |
luteinizing hormone/choriogonadotropin receptor |
decreases expression multiple interactions increases expression |
ISO EXP |
Thiamethoxam results in decreased expression of LHCGR protein Plant Extracts inhibits the reaction [Thiamethoxam results in increased expression of LHCGR mRNA] |
CTD |
PMID:33533595 PMID:34181816 |
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NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
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Lst1 |
leukocyte specific transcript 1 |
increases expression |
ISO |
Thiamethoxam results in increased expression of LST1 mRNA |
CTD |
PMID:33533595 |
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NCBI chr20:3,634,680...3,639,731
Ensembl chr20:3,634,749...3,637,997
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Mc4r |
melanocortin 4 receptor |
decreases expression |
ISO |
Thiamethoxam results in decreased expression of MC4R mRNA |
CTD |
PMID:33533595 |
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NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719
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Mmp7 |
matrix metallopeptidase 7 |
increases expression |
ISO |
Thiamethoxam results in increased expression of MMP7 mRNA |
CTD |
PMID:33533595 |
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NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
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Nos2 |
nitric oxide synthase 2 |
decreases activity multiple interactions |
ISO |
Thiamethoxam metabolite results in decreased activity of NOS2 protein [Thiamethoxam metabolite results in decreased activity of NOS2 protein] which results in increased chemical synthesis of Formaldehyde |
CTD |
PMID:29197058 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Plcg2 |
phospholipase C, gamma 2 |
decreases expression |
ISO |
Thiamethoxam results in decreased expression of PLCG2 mRNA |
CTD |
PMID:33533595 |
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NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
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Prnp |
prion protein |
increases expression |
ISO |
Thiamethoxam results in increased expression of PRNP mRNA |
CTD |
PMID:33533595 |
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NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
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Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
decreases expression |
ISO |
Thiamethoxam results in decreased expression of PTGS2 mRNA |
CTD |
PMID:33533595 |
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NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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Pthlh |
parathyroid hormone-like hormone |
decreases expression |
ISO |
Thiamethoxam results in decreased expression of PTHLH mRNA |
CTD |
PMID:33533595 |
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NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
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Ptx3 |
pentraxin 3 |
increases expression |
ISO |
Thiamethoxam results in increased expression of PTX3 mRNA |
CTD |
PMID:33533595 |
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NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
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G |
Scarb1 |
scavenger receptor class B, member 1 |
multiple interactions decreases expression |
EXP |
Plant Extracts inhibits the reaction [Thiamethoxam results in decreased expression of SCARB1 mRNA] |
CTD |
PMID:34181816 |
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NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
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Sesn2 |
sestrin 2 |
increases expression |
ISO |
Thiamethoxam results in increased expression of SESN2 mRNA |
CTD |
PMID:33533595 |
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NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
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G |
Slc22a2 |
solute carrier family 22 member 2 |
decreases activity |
ISO |
Thiamethoxam results in decreased activity of SLC22A2 protein |
CTD |
PMID:31364238 |
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NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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G |
Slc7a11 |
solute carrier family 7 member 11 |
increases expression |
ISO |
Thiamethoxam results in increased expression of SLC7A11 mRNA |
CTD |
PMID:33533595 |
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NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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G |
Star |
steroidogenic acute regulatory protein |
decreases expression multiple interactions |
EXP |
Thiamethoxam results in decreased expression of STAR mRNA Plant Extracts inhibits the reaction [Thiamethoxam results in decreased expression of STAR mRNA] |
CTD |
PMID:34181816 |
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NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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G |
Stc2 |
stanniocalcin 2 |
increases expression |
ISO |
Thiamethoxam results in increased expression of STC2 mRNA |
CTD |
PMID:33533595 |
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NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973
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G |
Thbs4 |
thrombospondin 4 |
decreases expression |
ISO |
Thiamethoxam results in decreased expression of THBS4 mRNA |
CTD |
PMID:33533595 |
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NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313
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G |
Thra |
thyroid hormone receptor alpha |
affects binding |
ISO |
Thiamethoxam binds to THRA protein |
CTD |
PMID:31550567 |
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NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
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G |
Tnnt2 |
troponin T2, cardiac type |
increases secretion multiple interactions |
EXP |
Thiamethoxam results in increased secretion of TNNT2 protein fenugreek seed meal inhibits the reaction [Thiamethoxam results in increased secretion of TNNT2 protein]; Polysaccharides inhibits the reaction [Thiamethoxam results in increased secretion of TNNT2 protein] |
CTD |
PMID:30520268 |
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NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388
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G |
Atf3 |
activating transcription factor 3 |
multiple interactions |
ISO |
N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [deoxynivalenol results in decreased degradation of ATF3 protein] |
CTD |
PMID:19101521 |
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NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in increased expression of BAX protein] |
CTD |
PMID:20540935 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Casp3 |
caspase 3 |
multiple interactions |
ISO EXP |
[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in increased expression of CASP3 protein] N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Colchicine results in increased activity of CASP3 protein] |
CTD |
PMID:20300959 PMID:20540935 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp9 |
caspase 9 |
multiple interactions |
ISO |
[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in increased expression of CASP9 protein] |
CTD |
PMID:20540935 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Ccnb1 |
cyclin B1 |
multiple interactions |
ISO |
[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CCNB1 protein] |
CTD |
PMID:20540935 |
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NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnd1 |
cyclin D1 |
multiple interactions |
ISO |
[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CCND1 protein] |
CTD |
PMID:20540935 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccne1 |
cyclin E1 |
multiple interactions |
ISO |
[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CCNE1 protein] |
CTD |
PMID:20540935 |
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NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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G |
Cdk2 |
cyclin dependent kinase 2 |
multiple interactions |
ISO |
[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CDK2 protein] |
CTD |
PMID:20540935 |
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NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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G |
Cdk4 |
cyclin-dependent kinase 4 |
multiple interactions |
ISO |
[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CDK4 protein] |
CTD |
PMID:20540935 |
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NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions |
ISO |
N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Arsenic Trioxide results in decreased expression of CTNNB1 protein] |
CTD |
PMID:32305283 |
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NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Gria1 |
glutamate ionotropic receptor AMPA type subunit 1 |
affects localization |
EXP |
N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea affects the localization of GRIA1 protein |
CTD |
PMID:20534517 |
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NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
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G |
Gria2 |
glutamate ionotropic receptor AMPA type subunit 2 |
affects localization |
EXP |
N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea affects the localization of GRIA2 protein |
CTD |
PMID:20534517 |
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NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions decreases activity |
ISO EXP |
[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [Troglitazone results in decreased expression of CCNB1 protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [Troglitazone results in decreased expression of CCND1 protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [Troglitazone results in decreased expression of CCNE1 protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [Troglitazone results in decreased expression of CDK2 protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [Troglitazone results in decreased expression of CDK4 protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [Troglitazone results in increased expression of BAX protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [Troglitazone results in increased expression of CASP3 protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [Troglitazone results in increased expression of CASP9 protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] which results in decreased susceptibility to Okadaic Acid; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] which results in decreased susceptibility to Proadifen; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] which results in increased susceptibility to Troglitazone; N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of GSK3B protein]; N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein modified form]; N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein] |
CTD |
PMID:16202587 PMID:20540935 PMID:21715663 PMID:22683934 PMID:32305283 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Mapt |
microtubule-associated protein tau |
multiple interactions |
ISO |
[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein] |
CTD |
PMID:21715663 |
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NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
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G |
Mcl1 |
MCL1 apoptosis regulator, BCL2 family member |
multiple interactions |
ISO |
N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Arsenic Trioxide results in decreased expression of MCL1 protein] |
CTD |
PMID:32305283 |
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NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
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G |
Dio1 |
iodothyronine deiodinase 1 |
decreases activity |
ISO |
Kathon 930 results in decreased activity of DIO1 protein |
CTD |
PMID:30561685 |
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NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
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G |
Dio2 |
iodothyronine deiodinase 2 |
decreases activity |
ISO |
Kathon 930 results in decreased activity of DIO2 protein |
CTD |
PMID:30561685 |
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NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
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G |
Dio3 |
iodothyronine deiodinase 3 |
decreases activity |
ISO |
Kathon 930 results in decreased activity of DIO3 protein |
CTD |
PMID:30561685 |
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NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
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G |
Iyd |
iodotyrosine deiodinase |
multiple interactions |
ISO |
Kathon 930 inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] |
CTD |
PMID:33352258 |
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NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
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G |
Acaca |
acetyl-CoA carboxylase alpha |
multiple interactions |
ISO |
Chlormethiazole inhibits the reaction [Ethanol results in decreased phosphorylation of and results in decreased expression of ACACA protein] |
CTD |
PMID:24892905 |
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NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
multiple interactions |
ISO |
Chlormethiazole inhibits the reaction [Ethanol results in decreased expression of ADIPOQ] |
CTD |
PMID:25162931 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
ISO |
Chlormethiazole inhibits the reaction [Ethanol results in decreased phosphorylation of AKT1 protein] |
CTD |
PMID:24892905 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions |
EXP |
Chlormethiazole inhibits the reaction [Acetaminophen results in increased degradation of CDKN1A protein] |
CTD |
PMID:16330492 |
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
decreases expression |
EXP |
Chlormethiazole results in decreased expression of CYP1A1 protein |
CTD |
PMID:10751552 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
decreases expression |
EXP |
Chlormethiazole results in decreased expression of CYP1A2 mRNA |
CTD |
PMID:10751552 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp2a3 |
cytochrome P450, family 2, subfamily a, polypeptide 3 |
multiple interactions |
ISO |
Chlormethiazole inhibits the reaction [Ethanol results in increased activity of CYP2A5 protein] |
CTD |
PMID:22552773 |
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NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions decreases activity decreases expression |
ISO EXP |
Chlormethiazole inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA]; Chlormethiazole inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]; Chlormethiazole inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein] Chlormethiazole results in decreased activity of CYP2E1 protein [Chlormethiazole results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone; Chlormethiazole inhibits the reaction [Docosahexaenoic Acids results in increased expression of CYP2E1 protein] Chlormethiazole results in decreased expression of CYP2E1 protein Chlormethiazole results in decreased expression of CYP2E1 mRNA; Chlormethiazole results in decreased expression of CYP2E1 protein Chlormethiazole inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]; Chlormethiazole inhibits the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride] |
CTD |
PMID:7601153 PMID:10751552 PMID:16330492 PMID:16963249 PMID:21684301 PMID:22552773 PMID:24892905 PMID:26599973 More...
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp2g1 |
cytochrome P450, family 2, subfamily g, polypeptide 1 |
decreases expression |
EXP |
Chlormethiazole results in decreased expression of CYP2G1 protein |
CTD |
PMID:10751552 |
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NCBI chr 1:82,145,635...82,156,862
Ensembl chr 1:82,145,073...82,156,828
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G |
Dgat2 |
diacylglycerol O-acyltransferase 2 |
multiple interactions |
ISO |
Chlormethiazole promotes the reaction [Ethanol results in increased expression of DGAT2 protein] |
CTD |
PMID:24892905 |
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NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
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G |
Ep300 |
E1A binding protein p300 |
multiple interactions |
ISO |
Chlormethiazole inhibits the reaction [Ethanol results in decreased expression of EP300 protein] |
CTD |
PMID:24892905 |
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NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
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G |
Fasn |
fatty acid synthase |
multiple interactions |
ISO |
Chlormethiazole inhibits the reaction [Ethanol results in decreased expression of FASN protein] |
CTD |
PMID:24892905 |
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NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions |
ISO |
Chlormethiazole inhibits the reaction [Ethanol results in decreased phosphorylation of GSK3B protein] |
CTD |
PMID:24892905 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
Chlormethiazole inhibits the reaction [Ethanol results in decreased phosphorylation of MAPK1 protein] |
CTD |
PMID:24892905 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
Chlormethiazole inhibits the reaction [Ethanol results in decreased phosphorylation of MAPK3 protein] |
CTD |
PMID:24892905 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
Chlormethiazole inhibits the reaction [Ethanol results in decreased expression of PPARA mRNA]; Chlormethiazole inhibits the reaction [Ethanol results in decreased expression of PPARA protein]; Chlormethiazole inhibits the reaction [Ethanol results in increased expression of PPARA protein] |
CTD |
PMID:24892905 PMID:25162931 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
multiple interactions |
ISO |
Chlormethiazole affects the reaction [Ethanol results in decreased expression of PPARGC1A mRNA]; Chlormethiazole inhibits the reaction [Ethanol results in decreased acetylation of PPARGC1A protein] |
CTD |
PMID:24892905 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Rxra |
retinoid X receptor alpha |
multiple interactions |
ISO |
Chlormethiazole affects the reaction [Ethanol affects the expression of RXRA mRNA] |
CTD |
PMID:24892905 |
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NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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G |
Sirt1 |
sirtuin 1 |
decreases expression multiple interactions |
ISO |
Chlormethiazole results in decreased expression of SIRT1 protein Chlormethiazole inhibits the reaction [Ethanol results in decreased expression of SIRT1 protein] |
CTD |
PMID:24892905 |
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NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
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G |
Th |
tyrosine hydroxylase |
multiple interactions |
ISO |
Chlormethiazole inhibits the reaction [Methamphetamine results in decreased activity of TH protein] |
CTD |
PMID:1381816 |
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NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
Chlormethiazole inhibits the reaction [Ethanol results in increased expression of TNF protein] |
CTD |
PMID:24892905 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tp53 |
tumor protein p53 |
multiple interactions |
EXP |
Chlormethiazole inhibits the reaction [Acetaminophen results in increased degradation of TP53 protein] |
CTD |
PMID:16330492 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Hsf1 |
heat shock transcription factor 1 |
increases activity |
ISO |
apratoxin A results in increased activity of HSF1 protein |
CTD |
PMID:34170685 |
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NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions increases expression |
ISO |
NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of GCLM mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of GCLM mRNA] benphothiamine metabolite results in increased expression of GCLM mRNA; benphothiamine results in increased expression of GCLM mRNA |
CTD |
PMID:29860433 |
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NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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G |
Gsr |
glutathione-disulfide reductase |
multiple interactions increases expression |
ISO |
NFE2L2 protein affects the reaction [benphothiamine results in increased expression of GSR mRNA] |
CTD |
PMID:29860433 |
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NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
ISO |
benphothiamine metabolite results in increased expression of HMOX1 mRNA; benphothiamine results in increased expression of HMOX1 mRNA benphothiamine inhibits the reaction [MAPT protein results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of HMOX1 mRNA] |
CTD |
PMID:29860433 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
[benphothiamine co-treated with MAPT protein] results in decreased expression of IL1B protein |
CTD |
PMID:29860433 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Mapt |
microtubule-associated protein tau |
decreases phosphorylation multiple interactions |
ISO |
benphothiamine results in decreased phosphorylation of MAPT protein [benphothiamine co-treated with MAPT protein] results in decreased expression of IL1B protein; [benphothiamine co-treated with MAPT protein] results in decreased expression of NOS2 protein; [benphothiamine co-treated with MAPT protein] results in decreased expression of PTGS2 protein; [benphothiamine co-treated with MAPT protein] results in decreased expression of RELA protein; [benphothiamine co-treated with MAPT protein] results in decreased expression of TNF protein; [benphothiamine co-treated with MAPT protein] results in increased expression of NQO1 mRNA; [benphothiamine co-treated with MAPT protein] results in increased expression of TXN mRNA; benphothiamine inhibits the reaction [MAPT protein results in decreased activity of TKT protein]; benphothiamine inhibits the reaction [MAPT protein results in decreased expression of NOS2 mRNA]; benphothiamine inhibits the reaction [MAPT protein results in decreased expression of PPARGC1A protein]; benphothiamine inhibits the reaction [MAPT protein results in decreased expression of SOD1 protein]; benphothiamine inhibits the reaction [MAPT protein results in increased expression of HMOX1 mRNA] |
CTD |
PMID:29860433 |
|
NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
ISO |
NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of GCLM mRNA]; NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of GCLM mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of GSR mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of NQO1 mRNA] |
CTD |
PMID:29860433 |
|
NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
[benphothiamine co-treated with MAPT protein] results in decreased expression of NOS2 protein; benphothiamine inhibits the reaction [MAPT protein results in decreased expression of NOS2 mRNA] |
CTD |
PMID:29860433 |
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression multiple interactions |
ISO |
benphothiamine metabolite results in increased expression of NQO1 mRNA; benphothiamine results in increased expression of NQO1 mRNA [benphothiamine co-treated with MAPT protein] results in increased expression of NQO1 mRNA; NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of NQO1 mRNA] |
CTD |
PMID:29860433 |
|
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
multiple interactions |
ISO |
benphothiamine inhibits the reaction [MAPT protein results in decreased expression of PPARGC1A protein] |
CTD |
PMID:29860433 |
|
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
[benphothiamine co-treated with MAPT protein] results in decreased expression of PTGS2 protein |
CTD |
PMID:29860433 |
|
NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
[benphothiamine co-treated with MAPT protein] results in decreased expression of RELA protein |
CTD |
PMID:29860433 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions |
ISO |
benphothiamine inhibits the reaction [MAPT protein results in decreased expression of SOD1 protein] |
CTD |
PMID:29860433 |
|
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Tkt |
transketolase |
multiple interactions |
EXP ISO |
[benphothiamine co-treated with Streptozocin] results in increased activity of TKT protein benphothiamine inhibits the reaction [MAPT protein results in decreased activity of TKT protein] |
CTD |
PMID:12592403 PMID:29860433 |
|
NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
[benphothiamine co-treated with MAPT protein] results in decreased expression of TNF protein |
CTD |
PMID:29860433 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Txn1 |
thioredoxin 1 |
multiple interactions |
ISO |
[benphothiamine co-treated with MAPT protein] results in increased expression of TXN mRNA |
CTD |
PMID:29860433 |
|
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression |
ISO |
camalexin metabolite results in increased expression of BAX mRNA |
CTD |
PMID:23339777 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression |
ISO |
camalexin metabolite results in decreased expression of BCL2 mRNA |
CTD |
PMID:23339777 |
|
NCBI chr13:22,689,783...22,853,920
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G |
Bcl2l1 |
Bcl2-like 1 |
decreases expression |
ISO |
camalexin metabolite results in decreased expression of BCL2L1 mRNA |
CTD |
PMID:23339777 |
|
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Slc22a6 |
solute carrier family 22 member 6 |
multiple interactions |
ISO |
cefoselis inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] |
CTD |
PMID:16098483 |
|
NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
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G |
Slc22a8 |
solute carrier family 22 member 8 |
increases uptake multiple interactions |
ISO |
SLC22A8 protein results in increased uptake of cefoselis cefoselis inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] |
CTD |
PMID:16098483 |
|
NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression |
ISO |
Cefotaxime results in increased expression of BAX protein |
CTD |
PMID:15012731 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Il10 |
interleukin 10 |
multiple interactions |
ISO |
Cefotaxime inhibits the reaction [Lipopolysaccharides results in increased secretion of IL10 protein] |
CTD |
PMID:16939481 |
|
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Pgd |
phosphogluconate dehydrogenase |
decreases activity |
EXP |
Cefotaxime results in decreased activity of PGD protein |
CTD |
PMID:15558954 |
|
NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778
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G |
RT1-CE5 |
RT1 class I, locus CE5 |
affects expression |
ISO |
Cefotaxime affects the expression of HLA-F mRNA |
CTD |
PMID:25811541 |
|
NCBI chr20:3,403,418...3,479,476
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G |
Tp53 |
tumor protein p53 |
increases expression |
ISO |
Cefotaxime results in increased expression of TP53 protein |
CTD |
PMID:15012731 |
|
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Ace2 |
angiotensin I converting enzyme 2 |
decreases expression |
EXP |
Ceftriaxone results in decreased expression of ACE2 mRNA |
CTD |
PMID:29745864 |
|
NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
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G |
Actb |
actin, beta |
increases expression |
EXP |
Ceftriaxone results in increased expression of ACTB mRNA |
CTD |
PMID:29745864 |
|
NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
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G |
Bace1 |
beta-secretase 1 |
decreases expression |
EXP |
Ceftriaxone results in decreased expression of BACE1 mRNA |
CTD |
PMID:29745864 |
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NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
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G |
Cat |
catalase |
decreases expression multiple interactions |
ISO EXP |
Ceftriaxone results in decreased expression of CAT protein Ceftriaxone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased activity of CAT protein]; ropinirole promotes the reaction [Ceftriaxone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased activity of CAT protein]] |
CTD |
PMID:19442074 PMID:25053526 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Dhfr |
dihydrofolate reductase |
decreases activity |
ISO |
Ceftriaxone results in decreased activity of DHFR protein |
CTD |
PMID:25418905 |
|
NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
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G |
Ece1 |
endothelin converting enzyme 1 |
increases expression |
EXP |
Ceftriaxone results in increased expression of ECE1 mRNA |
CTD |
PMID:29745864 |
|
NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371
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G |
Epo |
erythropoietin |
increases expression |
EXP |
Ceftriaxone results in increased expression of EPO mRNA |
CTD |
PMID:29745864 |
|
NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
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G |
Ide |
insulin degrading enzyme |
increases expression |
EXP |
Ceftriaxone results in increased expression of IDE mRNA |
CTD |
PMID:29745864 |
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NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
EXP |
Ceftriaxone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B protein]; ropinirole promotes the reaction [Ceftriaxone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B protein]] |
CTD |
PMID:25053526 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Mme |
membrane metallo-endopeptidase |
increases expression |
EXP |
Ceftriaxone results in increased expression of MME mRNA |
CTD |
PMID:29745864 |
|
NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792
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G |
Slc1a2 |
solute carrier family 1 member 2 |
multiple interactions increases expression |
EXP |
Ceftriaxone inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of SLC1A2 protein]; Ceftriaxone inhibits the reaction [Cocaine results in decreased expression of SLC1A2 protein]; Ceftriaxone inhibits the reaction [JZL195 results in decreased expression of and affects the folding of SLC1A2 protein]; Ceftriaxone promotes the reaction [Kainic Acid results in increased expression of SLC1A2 protein] Ceftriaxone results in increased expression of SLC1A2 protein |
CTD |
PMID:19625514 PMID:19717140 PMID:28257918 PMID:29045497 PMID:29432698 |
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NCBI chr 3:89,005,129...89,126,498
Ensembl chr 3:89,005,129...89,126,498
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G |
Slc7a11 |
solute carrier family 7 member 11 |
multiple interactions |
EXP |
Ceftriaxone inhibits the reaction [Cocaine results in decreased expression of SLC7A11 protein] |
CTD |
PMID:19717140 |
|
NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
EXP |
Ceftriaxone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TNF protein]; ropinirole promotes the reaction [Ceftriaxone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TNF protein]] |
CTD |
PMID:25053526 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Actb |
actin, beta |
increases metabolic processing |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of ACTB protein |
CTD |
PMID:29267982 |
|
NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
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G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
increases activity |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased activity of AKR1C2 promoter |
CTD |
PMID:21195160 |
|
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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G |
Alb |
albumin |
increases metabolic processing |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of ALB protein |
CTD |
PMID:29267982 |
|
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
increases expression |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased expression of CCL4 protein |
CTD |
PMID:18353026 |
|
NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
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G |
Cxcl14 |
C-X-C motif chemokine ligand 14 |
multiple interactions |
ISO |
[5-chloro-2-methyl-4-isothiazolin-3-one co-treated with 2-methyl-4-isothiazolin-3-one] results in decreased expression of CXCL14 protein |
CTD |
PMID:31734321 |
|
NCBI chr17:8,317,933...8,325,956
Ensembl chr17:8,317,933...8,324,839
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G |
Dhx9 |
DExH-box helicase 9 |
increases metabolic processing |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of DHX9 protein |
CTD |
PMID:29267982 |
|
NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
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G |
Hbb |
hemoglobin subunit beta |
increases metabolic processing |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of HBB protein |
CTD |
PMID:29267982 |
|
NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
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G |
Hist1h4m |
histone cluster 1, H4m |
increases metabolic processing |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of H4C1 protein |
CTD |
PMID:29267982 |
|
NCBI chr17:42,698,054...42,698,365
Ensembl chr17:42,698,025...42,698,958
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G |
Hmox1 |
heme oxygenase 1 |
increases expression |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased expression of HMOX1 mRNA |
CTD |
PMID:20713136 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hnrnpk |
heterogeneous nuclear ribonucleoprotein K |
increases metabolic processing |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of HNRNPK protein |
CTD |
PMID:29267982 |
|
NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
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G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
increases metabolic processing |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of HSP90AA1 protein |
CTD |
PMID:29267982 |
|
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
increases metabolic processing |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of HSPA1A protein |
CTD |
PMID:29267982 |
|
|
|
G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
increases metabolic processing |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of HSPA8 protein |
CTD |
PMID:29267982 |
|
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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G |
Il2 |
interleukin 2 |
increases secretion |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased secretion of IL2 protein |
CTD |
PMID:22245253 |
|
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il6 |
interleukin 6 |
increases secretion |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased secretion of IL6 protein |
CTD |
PMID:22245253 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Lmna |
lamin A/C |
increases metabolic processing |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of LMNA protein |
CTD |
PMID:29267982 |
|
NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
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G |
Myh9 |
myosin, heavy chain 9 |
increases metabolic processing |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of MYH9 protein |
CTD |
PMID:29267982 |
|
NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457
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G |
Notch3 |
notch receptor 3 |
increases expression |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased expression of NOTCH3 mRNA |
CTD |
PMID:20713136 |
|
NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased expression of NQO1 mRNA |
CTD |
PMID:20491607 |
|
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Pkm |
pyruvate kinase M1/2 |
increases metabolic processing |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of PKM protein |
CTD |
PMID:29267982 |
|
NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
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G |
Pmaip1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
increases expression |
ISO |
5-chloro-2-methyl-4-isothiazolin-3-one results in increased expression of PMAIP1 mRNA |
CTD |
PMID:20713136 |
|
NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
ISO |
[5-chloro-2-methyl-4-isothiazolin-3-one co-treated with 2-methyl-4-isothiazolin-3-one] results in increased expression of VEGFA protein |
CTD |
PMID:25617811 |
|
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Abca13 |
ATP binding cassette subfamily A member 13 |
increases expression |
ISO |
clothianidin results in increased expression of ABCA13 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr14:83,873,397...84,376,138
Ensembl chr14:83,873,940...84,375,075
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G |
Abcb6 |
ATP binding cassette subfamily B member 6 |
decreases expression |
ISO |
clothianidin results in decreased expression of ABCB6 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
increases expression |
ISO |
clothianidin results in increased expression of ABCC1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
|
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G |
Abcc3 |
ATP binding cassette subfamily C member 3 |
multiple interactions increases expression |
EXP |
[enilconazole co-treated with clothianidin] results in increased expression of ABCC3 mRNA; [thiacloprid co-treated with clothianidin] results in increased expression of ABCC3 mRNA clothianidin results in increased expression of ABCC3 mRNA |
CTD |
PMID:33426623 |
|
NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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G |
Abcd2 |
ATP binding cassette subfamily D member 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of ABCD2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:122,263,034...122,311,642
Ensembl chr 7:122,263,032...122,311,642
|
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G |
Abcd3 |
ATP binding cassette subfamily D member 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of ABCD3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020
|
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of ABCG1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
|
|
G |
Abhd4 |
abhydrolase domain containing 4, N-acyl phospholipase B |
decreases expression |
ISO |
clothianidin results in decreased expression of ABHD4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966
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G |
Abi3bp |
ABI family member 3 binding protein |
decreases expression |
ISO |
clothianidin results in decreased expression of ABI3BP mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:43,912,187...44,128,888
Ensembl chr11:43,913,043...44,128,929
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G |
Adcy2 |
adenylate cyclase 2 |
increases expression |
ISO |
clothianidin results in increased expression of ADCY2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:34,375,639...34,822,237
Ensembl chr 1:34,375,895...34,822,236
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G |
Adcy4 |
adenylate cyclase 4 |
decreases expression |
ISO |
clothianidin results in decreased expression of ADCY4 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr15:29,266,280...29,282,153
Ensembl chr15:29,266,287...29,282,108
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G |
Adgrb2 |
adhesion G protein-coupled receptor B2 |
decreases expression |
ISO |
clothianidin results in decreased expression of ADGRB2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 5:142,299,190...142,362,540
Ensembl chr 5:142,331,329...142,362,540
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G |
Adgrf5 |
adhesion G protein-coupled receptor F5 |
decreases expression |
ISO |
clothianidin results in decreased expression of ADGRF5 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 9:17,517,596...17,624,107
Ensembl chr 9:17,520,009...17,623,968
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G |
Adgrg6 |
adhesion G protein-coupled receptor G6 |
decreases expression |
ISO |
clothianidin results in decreased expression of ADGRG6 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:8,812,889...8,954,239
Ensembl chr 1:8,812,904...8,954,123
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G |
Adrb2 |
adrenoceptor beta 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of ADRB2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
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G |
Aff1-as1 |
AFF1 antisense RNA 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of C4ORF36 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr14:6,058,581...6,065,848
Ensembl chr14:6,058,581...6,065,847
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G |
Agbl3 |
AGBL carboxypeptidase 3 |
increases expression |
ISO |
clothianidin results in increased expression of AGBL3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:63,448,789...63,535,538
Ensembl chr 4:63,453,940...63,531,188
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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
increases expression multiple interactions |
EXP |
clothianidin results in increased expression of ALDH1A1 mRNA [enilconazole co-treated with clothianidin] results in increased expression of ALDH1A1 mRNA; [thiacloprid co-treated with clothianidin] results in increased expression of ALDH1A1 mRNA |
CTD |
PMID:33426623 |
|
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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G |
Amz1 |
archaelysin family metallopeptidase 1 |
increases expression |
ISO |
clothianidin results in increased expression of AMZ1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr12:13,886,533...13,924,275
Ensembl chr12:13,891,123...13,909,783
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G |
Ank3 |
ankyrin 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of ANK3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
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G |
Ankrd37 |
ankyrin repeat domain 37 |
decreases expression |
ISO |
clothianidin results in decreased expression of ANKRD37 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr16:46,269,025...46,271,971
Ensembl chr16:46,268,443...46,271,963
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G |
Aplf |
aprataxin and PNKP like factor |
increases expression |
ISO |
clothianidin results in increased expression of APLF mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:120,070,471...120,122,656
Ensembl chr 4:120,070,471...120,122,633
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G |
Arhgap17 |
Rho GTPase activating protein 17 |
increases expression |
ISO |
clothianidin results in increased expression of ARHGAP17 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:177,807,579...177,897,027
Ensembl chr 1:177,807,583...177,896,854
|
|
G |
Arhgef2 |
Rho/Rac guanine nucleotide exchange factor 2 |
increases expression |
ISO |
clothianidin results in increased expression of ARHGEF2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
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G |
Arih2os |
ARIH2 opposite strand lncRNA |
increases expression |
ISO |
clothianidin results in increased expression of ARIH2OS mRNA |
CTD |
PMID:31626844 |
|
|
|
G |
Arl11 |
ADP-ribosylation factor like GTPase 11 |
increases expression |
ISO |
clothianidin results in increased expression of ARL11 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:35,483,330...35,485,579
Ensembl chr15:35,480,018...35,496,596
|
|
G |
Arl6 |
ADP-ribosylation factor like GTPase 6 |
increases expression |
ISO |
clothianidin results in increased expression of ARL6 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:40,711,878...40,738,254
Ensembl chr11:40,712,022...40,737,937
|
|
G |
Asb11 |
ankyrin repeat and SOCS box containing 11 |
increases expression |
ISO |
clothianidin results in increased expression of ASB11 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr X:30,014,485...30,037,808
Ensembl chr X:29,992,416...30,037,807
|
|
G |
Asphd1 |
aspartate beta-hydroxylase domain containing 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of ASPHD1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:181,552,974...181,556,842
Ensembl chr 1:181,552,884...181,556,090
|
|
G |
Atp1a2 |
ATPase Na+/K+ transporting subunit alpha 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of ATP1A2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
|
|
G |
Atp23 |
ATP23 metallopeptidase and ATP synthase assembly factor homolog |
increases expression |
ISO |
clothianidin results in increased expression of XRCC6BP1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:62,714,752...62,729,893
Ensembl chr 7:62,714,785...62,729,862
|
|
G |
Atp2b3 |
ATPase plasma membrane Ca2+ transporting 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of ATP2B3 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr X:151,216,483...151,289,069
Ensembl chr X:151,216,507...151,286,775
|
|
G |
Atp6v0d2 |
ATPase H+ transporting V0 subunit D2 |
increases expression |
ISO |
clothianidin results in increased expression of ATP6V0D2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354
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G |
Awat1 |
acyl-CoA wax alcohol acyltransferase 1 |
increases expression |
ISO |
clothianidin results in increased expression of AWAT1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr X:65,668,205...65,674,450
Ensembl chr X:65,668,205...65,674,450
|
|
G |
Axin1 |
axin 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of AXIN1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:15,163,684...15,215,615
Ensembl chr10:15,163,684...15,215,615
|
|
G |
Azin2 |
antizyme inhibitor 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of AZIN2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 5:141,281,310...141,310,415
Ensembl chr 5:141,281,249...141,310,397
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|
G |
Barhl1 |
BarH-like homeobox 1 |
increases expression |
ISO |
clothianidin results in increased expression of BARHL1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:12,241,327...12,248,649
Ensembl chr 3:12,241,327...12,248,649
|
|
G |
Bcr |
BCR activator of RhoGEF and GTPase |
decreases expression |
ISO |
clothianidin results in decreased expression of BCR mRNA |
CTD |
PMID:31626844 |
|
NCBI chr20:13,471,679...13,596,497
Ensembl chr20:13,471,668...13,597,016
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|
G |
Bicd2 |
BICD cargo adaptor 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of BICD2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr17:15,259,773...15,304,889
Ensembl chr17:15,259,773...15,304,889
|
|
G |
Bricd5 |
BRICHOS domain containing 5 |
decreases expression |
ISO |
clothianidin results in decreased expression of BRICD5 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr10:13,498,726...13,500,259
Ensembl chr10:13,498,381...13,500,259
|
|
G |
C2cd4b |
C2 calcium-dependent domain containing 4B |
increases expression |
ISO |
clothianidin results in increased expression of C2CD4B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:68,372,793...68,396,477
Ensembl chr 8:68,384,847...68,396,328
|
|
G |
Cacnb2 |
calcium voltage-gated channel auxiliary subunit beta 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of CACNB2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106
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|
G |
Calhm3 |
calcium homeostasis modulator 3 |
increases expression |
ISO |
clothianidin results in increased expression of CALHM3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:246,043,258...246,048,259
Ensembl chr 1:246,043,258...246,048,259
|
|
G |
Capn5 |
calpain 5 |
increases expression |
ISO |
clothianidin results in increased expression of CAPN5 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 1:152,416,252...152,472,923
Ensembl chr 1:152,416,252...152,472,923
|
|
G |
Caps |
calcyphosine |
decreases expression |
ISO |
clothianidin results in decreased expression of CAPS mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 9:1,544,597...1,545,631
Ensembl chr 9:1,544,719...1,545,647
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|
G |
Car3 |
carbonic anhydrase 3 |
increases expression |
ISO |
clothianidin results in increased expression of CA3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
|
|
G |
Carmil1 |
capping protein regulator and myosin 1 linker 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of LRRC16A mRNA |
CTD |
PMID:31626844 |
|
NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326
|
|
G |
Carmil3 |
capping protein regulator and myosin 1 linker 3 |
increases expression |
ISO |
clothianidin results in increased expression of CARMIL3 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr15:28,978,440...28,995,865
Ensembl chr15:28,979,007...28,996,225
|
|
G |
Ccdc17 |
coiled-coil domain containing 17 |
decreases expression |
ISO |
clothianidin results in decreased expression of CCDC17 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 5:130,051,158...130,056,676
Ensembl chr 5:130,045,938...130,056,673
|
|
G |
Ccdc8 |
coiled-coil domain containing 8 |
increases expression |
ISO |
clothianidin results in increased expression of CCDC8 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:77,679,521...77,682,849
Ensembl chr 1:77,679,218...77,683,090
|
|
G |
Ccser1 |
coiled-coil serine-rich protein 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of CCSER1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:90,153,873...91,391,441
Ensembl chr 4:90,292,780...91,388,786
|
|
G |
Cd226 |
CD226 molecule |
decreases expression |
ISO |
clothianidin results in decreased expression of CD226 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051
|
|
G |
Cd34 |
CD34 molecule |
increases expression |
ISO |
clothianidin results in increased expression of CD34 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr13:106,480,074...106,499,462
Ensembl chr13:106,480,043...106,499,832
|
|
G |
Cd74 |
CD74 molecule |
increases expression |
ISO |
clothianidin results in increased expression of CD74 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
|
|
G |
Cd8b |
CD8b molecule |
increases expression |
ISO |
clothianidin results in increased expression of CD8B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:103,312,596...103,328,523
Ensembl chr 4:103,312,578...103,328,553
|
|
G |
Cdh8 |
cadherin 8 |
decreases expression |
ISO |
clothianidin results in decreased expression of CDH8 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr19:5,494,038...5,901,810
Ensembl chr19:5,494,174...5,895,669
|
|
G |
Ceacam6 |
CEA cell adhesion molecule 6 |
increases expression |
ISO |
clothianidin results in increased expression of CEACAM6 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:80,416,531...80,434,668
Ensembl chr 1:80,416,531...80,434,668
|
|
G |
Cemip |
cell migration inducing hyaluronidase 1 |
increases expression |
ISO |
clothianidin results in increased expression of CEMIP mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415
|
|
G |
Ces2h |
carboxylesterase 2H |
multiple interactions |
ISO |
[clothianidin co-treated with thiacloprid] results in increased expression of CES2 protein |
CTD |
PMID:32201337 |
|
NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
|
|
G |
Cfap107 |
cilia and flagella associated protein 107 |
decreases expression |
ISO |
clothianidin results in decreased expression of CFAP107 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 5:156,212,385...156,231,481
Ensembl chr 5:156,212,385...156,231,481
|
|
G |
Chrna4 |
cholinergic receptor nicotinic alpha 4 subunit |
multiple interactions |
ISO |
clothianidin promotes the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] |
CTD |
PMID:21538459 |
|
NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
|
|
G |
Chrnb2 |
cholinergic receptor nicotinic beta 2 subunit |
multiple interactions |
EXP ISO |
clothianidin results in increased activity of [NACHRA1 protein co-treated with CHRNB2 protein]; clothianidin results in increased activity of [NACHRA8 protein co-treated with CHRNB2 protein] clothianidin promotes the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] |
CTD |
PMID:16981889 PMID:21538459 PMID:25459289 |
|
NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
|
|
G |
Chst3 |
carbohydrate sulfotransferase 3 |
increases expression |
ISO |
clothianidin results in increased expression of CHST3 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr20:28,114,387...28,152,046
Ensembl chr20:28,114,404...28,121,807
|
|
G |
Clec3b |
C-type lectin domain family 3, member B |
increases expression |
ISO |
clothianidin results in increased expression of CLEC3B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:122,810,091...122,817,039
Ensembl chr 8:122,810,149...122,815,835
|
|
G |
Cmtm5 |
CKLF-like MARVEL transmembrane domain containing 5 |
increases expression |
ISO |
clothianidin results in increased expression of CMTM5 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:28,412,624...28,415,304
Ensembl chr15:28,412,624...28,415,287
|
|
G |
Cntnap1 |
contactin associated protein 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of CNTNAP1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:86,109,850...86,125,612
Ensembl chr10:86,111,643...86,125,611
|
|
G |
Col12a1 |
collagen type XII alpha 1 chain |
decreases expression |
ISO |
clothianidin results in decreased expression of COL12A1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686
|
|
G |
Col1a1 |
collagen type I alpha 1 chain |
decreases expression |
ISO |
clothianidin results in decreased expression of COL1A1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
|
|
G |
Col6a2 |
collagen type VI alpha 2 chain |
increases expression |
ISO |
clothianidin results in increased expression of COL6A2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564
|
|
G |
Col7a1 |
collagen type VII alpha 1 chain |
decreases expression |
ISO |
clothianidin results in decreased expression of COL7A1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 8:109,604,877...109,637,252
Ensembl chr 8:109,604,861...109,637,252
|
|
G |
Coro2b |
coronin 2B |
decreases expression |
ISO |
clothianidin results in decreased expression of CORO2B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:62,906,861...63,017,295
Ensembl chr 8:62,906,867...63,017,302
|
|
G |
Cpeb3 |
cytoplasmic polyadenylation element binding protein 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of CPEB3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:234,749,138...234,931,219
Ensembl chr 1:234,751,733...234,931,560
|
|
G |
Cpne4 |
copine 4 |
increases expression |
ISO |
clothianidin results in increased expression of CPNE4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:105,177,376...105,653,075
Ensembl chr 8:105,177,376...105,653,068
|
|
G |
Csmd1 |
CUB and Sushi multiple domains 1 |
increases expression |
ISO |
clothianidin results in increased expression of CSMD1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr16:72,218,189...73,818,380
Ensembl chr16:72,218,503...73,817,614
|
|
G |
Cxadr |
CXADR, Ig-like cell adhesion molecule |
increases expression |
ISO |
clothianidin results in increased expression of CXADR mRNA |
CTD |
PMID:29044138 |
|
NCBI chr11:16,982,752...17,030,078
Ensembl chr11:16,982,860...17,030,046
|
|
G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions increases expression |
ISO |
[clothianidin co-treated with enilconazole] results in increased expression of CYP1A2 mRNA; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in increased expression of CYP1A2 mRNA clothianidin results in increased expression of CYP1A2 mRNA |
CTD |
PMID:32201337 |
|
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
|
|
G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[clothianidin co-treated with enilconazole] results in increased expression of CYP1B1 protein |
CTD |
PMID:32201337 |
|
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
|
|
G |
Cyp2b2 |
cytochrome P450, family 2, subfamily b, polypeptide 2 |
increases expression multiple interactions |
EXP |
clothianidin results in increased expression of CYP2B2 mRNA [enilconazole co-treated with clothianidin] results in increased expression of CYP2B2 mRNA; [thiacloprid co-treated with clothianidin] results in increased expression of CYP2B2 mRNA |
CTD |
PMID:33426623 |
|
NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
|
|
G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
multiple interactions |
ISO |
[clothianidin co-treated with thiacloprid] results in increased expression of CYP2B6 protein |
CTD |
PMID:32201337 |
|
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
|
|
G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
decreases expression multiple interactions |
ISO |
clothianidin results in decreased expression of CYP2E1 mRNA [clothianidin co-treated with enilconazole] results in decreased expression of CYP2E1 mRNA; [clothianidin co-treated with thiacloprid] results in increased expression of CYP2E1 protein; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in decreased expression of CYP2E1 mRNA; [thiacloprid co-treated with clothianidin] results in decreased expression of CYP2E1 mRNA |
CTD |
PMID:32201337 |
|
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
|
|
G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
increases expression multiple interactions |
ISO |
clothianidin results in increased expression of CYP3A4 mRNA [clothianidin co-treated with enilconazole] results in increased expression of CYP3A4 mRNA; [clothianidin co-treated with enilconazole] results in increased expression of CYP3A4 protein; [clothianidin co-treated with thiacloprid] results in increased expression of CYP3A4 protein; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in increased expression of CYP3A4 mRNA |
CTD |
PMID:32201337 |
|
NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
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|
G |
Cyp3a23-3a1 |
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 |
multiple interactions increases expression |
EXP |
[enilconazole co-treated with clothianidin] results in increased expression of CYP3A23-3A1 mRNA; [thiacloprid co-treated with clothianidin] results in increased expression of CYP3A23-3A1 mRNA clothianidin results in increased expression of CYP3A23-3A1 mRNA |
CTD |
PMID:33426623 |
|
NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
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|
G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
multiple interactions increases expression |
ISO |
[clothianidin co-treated with enilconazole] results in increased expression of CYP3A5 protein; [thiacloprid co-treated with clothianidin] results in increased expression of CYP3A5 mRNA clothianidin results in increased expression of CYP3A5 mRNA |
CTD |
PMID:32201337 |
|
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
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|
G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
multiple interactions decreases expression |
EXP |
[enilconazole co-treated with clothianidin] results in decreased expression of CYP7A1 mRNA; [thiacloprid co-treated with clothianidin] results in decreased expression of CYP7A1 mRNA clothianidin results in decreased expression of CYP7A1 mRNA |
CTD |
PMID:33426623 |
|
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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|
G |
Cyth4 |
cytohesin 4 |
increases expression |
ISO |
clothianidin results in increased expression of CYTH4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:110,152,232...110,176,741
Ensembl chr 7:110,152,272...110,176,741
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G |
Dact1 |
dishevelled-binding antagonist of beta-catenin 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of DACT1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906
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|
G |
Defa5 |
defensin alpha 5 |
decreases expression |
ISO |
clothianidin results in decreased expression of DEFA5 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr16:70,342,530...70,344,836
Ensembl chr16:70,342,530...70,344,836
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|
G |
Des |
desmin |
increases expression |
ISO |
clothianidin results in increased expression of DES mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
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G |
Dgkd |
diacylglycerol kinase, delta |
increases expression |
ISO |
clothianidin results in increased expression of DGKD mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 9:88,516,686...88,607,349
Ensembl chr 9:88,516,715...88,607,345
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|
G |
Dio3 |
iodothyronine deiodinase 3 |
increases expression |
ISO |
clothianidin results in increased expression of DIO3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
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|
G |
Dll3 |
delta like canonical Notch ligand 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of DLL3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:83,562,011...83,570,008
Ensembl chr 1:83,562,014...83,569,750
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G |
Dnai7 |
dynein axonemal intermediate chain 7 |
decreases expression |
ISO |
clothianidin results in decreased expression of DNAI7 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:178,143,499...178,179,871
Ensembl chr 4:178,143,500...178,179,980
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|
G |
Dnajc21 |
DnaJ heat shock protein family (Hsp40) member C21 |
increases expression |
ISO |
clothianidin results in increased expression of DNAJC21 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:59,419,505...59,446,743
Ensembl chr 2:59,419,510...59,446,752
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|
G |
Dnajc28 |
DnaJ heat shock protein family (Hsp40) member C28 |
decreases expression |
ISO |
clothianidin results in decreased expression of DNAJC28 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:30,855,566...30,858,386
Ensembl chr11:30,853,526...30,858,441
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G |
Dnajc5g |
DnaJ heat shock protein family (Hsp40) member C5 gamma |
increases expression |
ISO |
clothianidin results in increased expression of DNAJC5G mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:25,260,087...25,264,251
Ensembl chr 6:25,260,088...25,264,152
|
|
G |
Dnase1l2 |
deoxyribonuclease 1 like 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of DNASE1L2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr10:13,471,850...13,473,447
Ensembl chr10:13,471,479...13,473,763
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G |
Dnhd1 |
dynein heavy chain domain 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of DNHD1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 1:159,990,785...160,077,990
Ensembl chr 1:159,990,438...160,074,858
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|
G |
Dok5 |
docking protein 5 |
decreases expression |
ISO |
clothianidin results in decreased expression of DOK5 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:159,515,886...159,652,811
Ensembl chr 3:159,515,893...159,652,810
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|
G |
Dus3l |
dihydrouridine synthase 3-like |
increases expression |
ISO |
clothianidin results in increased expression of DUS3L mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 9:1,593,491...1,598,663
Ensembl chr 9:1,594,123...1,598,655
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G |
Dusp15 |
dual specificity phosphatase 15 |
increases expression |
ISO |
clothianidin results in increased expression of DUSP15 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 3:141,408,495...141,419,137
Ensembl chr 3:141,408,498...141,418,999
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|
G |
Dusp16 |
dual specificity phosphatase 16 |
decreases expression |
ISO |
clothianidin results in decreased expression of DUSP16 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:167,546,780...167,629,949
Ensembl chr 4:167,548,155...167,629,980
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|
G |
Eaf2 |
ELL associated factor 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of EAF2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:63,960,200...64,004,610
Ensembl chr11:63,960,200...64,004,610
|
|
G |
Ece2 |
endothelin-converting enzyme 2 |
increases expression |
ISO |
clothianidin results in increased expression of ECE2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:80,259,130...80,299,685
Ensembl chr11:80,263,162...80,278,428
|
|
G |
Efcab12 |
EF-hand calcium binding domain 12 |
decreases expression |
ISO |
clothianidin results in decreased expression of EFCAB12 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 4:148,869,381...148,892,922
Ensembl chr 4:148,869,387...148,890,560
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G |
Efs |
embryonal Fyn-associated substrate |
decreases expression |
ISO |
clothianidin results in decreased expression of EFS mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:28,392,417...28,403,016
Ensembl chr15:28,392,187...28,401,902
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|
G |
Eif3f |
eukaryotic translation initiation factor 3, subunit F |
decreases expression |
ISO |
clothianidin results in decreased expression of EIF3F mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:162,934,220...162,943,204
Ensembl chr 1:162,934,212...162,943,204
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|
G |
Elf1 |
E74 like ETS transcription factor 1 |
increases expression |
ISO |
clothianidin results in increased expression of ELF1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:54,890,644...54,986,721
Ensembl chr15:54,865,616...54,986,699
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|
G |
Elmod1 |
ELMO domain containing 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of ELMOD1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:54,298,363...54,355,348
Ensembl chr 8:54,298,363...54,355,140
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|
G |
Eln |
elastin |
multiple interactions decreases expression |
EXP |
[enilconazole co-treated with clothianidin] results in decreased expression of ELN mRNA; [thiacloprid co-treated with clothianidin] results in decreased expression of ELN mRNA clothianidin results in decreased expression of ELN mRNA |
CTD |
PMID:33426623 |
|
NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
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|
G |
Enpp4 |
ectonucleotide pyrophosphatase/phosphodiesterase 4 |
increases expression |
ISO |
clothianidin results in increased expression of ENPP4 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 9:16,888,923...16,898,860
Ensembl chr 9:16,887,739...16,898,860
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|
G |
Epdr1 |
ependymin related 1 |
increases expression |
ISO |
clothianidin results in increased expression of EPDR1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr17:45,333,677...45,358,597
Ensembl chr17:45,333,956...45,358,594
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|
G |
Epn3 |
epsin 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of EPN3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:79,438,978...79,449,516
Ensembl chr10:79,438,978...79,447,356
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|
G |
Eps8 |
epidermal growth factor receptor pathway substrate 8 |
increases expression |
ISO |
clothianidin results in increased expression of EPS8 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873
|
|
G |
Erbb3 |
erb-b2 receptor tyrosine kinase 3 |
increases expression |
ISO |
clothianidin results in increased expression of ERBB3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
|
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G |
Ergic1 |
endoplasmic reticulum-golgi intermediate compartment 1 |
increases expression |
ISO |
clothianidin results in increased expression of ERGIC1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:16,531,192...16,627,183
Ensembl chr10:16,531,194...16,626,957
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|
G |
Exoc4 |
exocyst complex component 4 |
decreases expression |
ISO |
clothianidin results in decreased expression of EXOC4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:61,807,706...62,584,316
Ensembl chr 4:61,807,761...62,585,723
|
|
G |
Ezh2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
decreases expression |
ISO |
clothianidin results in decreased expression of EZH2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
|
|
G |
F2 |
coagulation factor II |
decreases expression |
ISO |
clothianidin results in decreased expression of F2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
|
|
G |
Fam110c |
family with sequence similarity 110, member C |
increases expression |
ISO |
clothianidin results in increased expression of FAM110C mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:47,638,466...47,644,723
Ensembl chr 6:47,638,276...47,644,634
|
|
G |
Fam131a |
family with sequence similarity 131, member A |
decreases expression |
ISO |
clothianidin results in decreased expression of FAM131A mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:80,211,577...80,221,527
Ensembl chr11:80,211,745...80,221,511
|
|
G |
Fam151b |
family with sequence similarity 151, member B |
decreases expression |
ISO |
clothianidin results in decreased expression of FAM151B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:23,674,317...23,710,420
Ensembl chr 2:23,674,318...23,710,403
|
|
G |
Fam169a |
family with sequence similarity 169, member A |
increases expression |
ISO |
clothianidin results in increased expression of FAM169A mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 2:28,384,162...28,441,361
Ensembl chr 2:28,383,784...28,438,910
|
|
G |
Fam229a |
family with sequence similarity 229, member A |
decreases expression |
ISO |
clothianidin results in decreased expression of FAM229A mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 5:141,829,716...141,830,705
Ensembl chr 5:141,828,664...141,830,705
|
|
G |
Fam243a |
family with sequence similarity 243 member A |
increases expression |
ISO |
clothianidin results in increased expression of C21ORF140 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:31,549,689...31,552,257
Ensembl chr11:31,544,426...31,552,290
|
|
G |
Fbxo33 |
F-box protein 33 |
decreases expression |
ISO |
clothianidin results in decreased expression of FBXO33 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:76,900,619...76,934,232
Ensembl chr 6:76,900,631...76,932,669
|
|
G |
Fcna |
ficolin A |
increases expression |
ISO |
clothianidin results in increased expression of FCN3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:8,445,904...8,449,128
Ensembl chr 3:8,445,907...8,449,105
|
|
G |
Fer1l4 |
fer-1-like family member 4 |
decreases expression |
ISO |
clothianidin results in decreased expression of FER1L4 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 3:144,536,099...144,571,634
Ensembl chr 3:144,536,099...144,571,634
|
|
G |
Filip1 |
filamin A interacting protein 1 |
increases expression |
ISO |
clothianidin results in increased expression of FILIP1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:80,761,283...80,956,556
Ensembl chr 8:80,764,604...80,922,549
|
|
G |
Fitm1 |
fat storage-inducing transmembrane protein 1 |
increases expression |
ISO |
clothianidin results in increased expression of FITM1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:29,064,746...29,066,015
Ensembl chr15:29,064,707...29,066,015
|
|
G |
Folr2 |
folate receptor beta |
increases expression |
ISO |
clothianidin results in increased expression of FOLR2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:156,200,044...156,218,380
Ensembl chr 1:156,200,060...156,205,724
|
|
G |
Foxo1 |
forkhead box O1 |
increases expression |
ISO |
clothianidin results in increased expression of FOXO1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
|
|
G |
Foxo4 |
forkhead box O4 |
decreases expression |
ISO |
clothianidin results in decreased expression of FOXO4 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr X:66,385,241...66,392,115
Ensembl chr X:66,385,558...66,392,115
|
|
G |
Fyb1 |
FYN binding protein 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of FYB mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629
|
|
G |
Gask1a |
golgi associated kinase 1A |
increases expression |
ISO |
clothianidin results in increased expression of FAM198A mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:121,610,779...121,643,742
Ensembl chr 8:121,610,787...121,642,942
|
|
G |
Ghrhr |
growth hormone releasing hormone receptor |
increases expression |
ISO |
clothianidin results in increased expression of GHRHR mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:84,498,159...84,532,847
Ensembl chr 4:84,500,212...84,532,776
|
|
G |
Gli1 |
GLI family zinc finger 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of GLI1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
|
|
G |
Gngt1 |
G protein subunit gamma transducin 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of GNGT1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:32,006,267...32,009,252
Ensembl chr 4:32,006,267...32,009,252
|
|
G |
Gpc6 |
glypican 6 |
increases expression |
ISO |
clothianidin results in increased expression of GPC6 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:94,030,218...95,027,883
Ensembl chr15:94,029,884...95,024,006
|
|
G |
Gpcpd1 |
glycerophosphocholine phosphodiesterase 1 |
increases expression |
ISO |
clothianidin results in increased expression of GPCPD1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:119,787,681...119,832,550
Ensembl chr 3:119,787,682...119,832,517
|
|
G |
Gpihbp1 |
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 |
increases expression |
ISO |
clothianidin results in increased expression of GPIHBP1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:107,285,584...107,288,702
Ensembl chr 7:107,285,654...107,288,702
|
|
G |
Gpx4 |
glutathione peroxidase 4 |
decreases expression |
ISO |
clothianidin results in decreased expression of GPX4 protein |
CTD |
PMID:25960033 |
|
NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
|
|
G |
Gramd1c |
GRAM domain containing 1C |
decreases expression |
ISO |
clothianidin results in decreased expression of GRAMD1C mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:56,633,229...56,718,570
Ensembl chr11:56,633,227...56,718,570
|
|
G |
Gramd2a |
GRAM domain containing 2A |
decreases expression |
ISO |
clothianidin results in decreased expression of GRAMD2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:60,079,744...60,117,788
Ensembl chr 8:60,080,338...60,115,842
|
|
G |
Gskip |
GSK3B interacting protein |
increases expression |
ISO |
clothianidin results in increased expression of GSKIP mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 6:124,586,087...124,609,106
Ensembl chr 6:124,586,070...124,609,100
|
|
G |
Gtf3c5 |
general transcription factor IIIC subunit 5 |
increases expression |
ISO |
clothianidin results in increased expression of GTF3C5 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:11,893,867...11,914,187
Ensembl chr 3:11,893,875...11,914,180
|
|
G |
Gtsf1l |
gametocyte specific factor 1-like |
increases expression |
ISO |
clothianidin results in increased expression of GTSF1L mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:151,736,020...151,736,764
Ensembl chr 3:151,735,997...151,736,863
|
|
G |
Gypc |
glycophorin C |
increases expression |
ISO |
clothianidin results in increased expression of GYPC mRNA |
CTD |
PMID:31626844 |
|
NCBI chr18:24,160,738...24,193,408
Ensembl chr18:24,160,739...24,193,204
|
|
G |
H1f7 |
H1.7 linker histone |
increases expression |
ISO |
clothianidin results in increased expression of H1-7 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:129,408,521...129,409,888
Ensembl chr 7:129,408,359...129,409,930
|
|
G |
Hacd2 |
3-hydroxyacyl-CoA dehydratase 2 |
increases expression |
ISO |
clothianidin results in increased expression of HACD2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr11:65,667,671...65,762,903
Ensembl chr11:65,670,281...65,762,889
|
|
G |
Hck |
HCK proto-oncogene, Src family tyrosine kinase |
increases expression |
ISO |
clothianidin results in increased expression of HCK mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693
|
|
G |
Hectd2 |
HECT domain E3 ubiquitin protein ligase 2 |
increases expression |
ISO |
clothianidin results in increased expression of HECTD2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 1:234,274,967...234,345,598
Ensembl chr 1:234,275,705...234,343,487
|
|
G |
Hecw2 |
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of HECW2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 9:55,359,462...55,753,106
Ensembl chr 9:55,365,203...55,580,327
|
|
G |
Hgf |
hepatocyte growth factor |
decreases expression |
ISO |
clothianidin results in decreased expression of HGF mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
|
|
G |
Hid1 |
HID1 domain containing |
decreases expression |
ISO |
clothianidin results in decreased expression of HID1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:100,589,555...100,610,050
Ensembl chr10:100,589,555...100,610,041
|
|
G |
Hmbs |
hydroxymethylbilane synthase |
increases expression |
ISO |
clothianidin results in increased expression of HMBS mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957
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Hnf1b |
HNF1 homeobox B |
increases expression |
ISO |
clothianidin results in increased expression of HNF1B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888
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Hnf4a |
hepatocyte nuclear factor 4, alpha |
increases expression |
ISO |
clothianidin results in increased expression of HNF4A mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
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Hnrnpk |
heterogeneous nuclear ribonucleoprotein K |
decreases expression |
ISO |
clothianidin results in decreased expression of HNRNPK mRNA |
CTD |
PMID:31626844 |
|
NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
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Il17re |
interleukin 17 receptor E |
decreases expression |
ISO |
clothianidin results in decreased expression of IL17RE mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 4:146,604,547...146,618,206
Ensembl chr 4:146,605,526...146,618,206
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G |
Il18bp |
interleukin 18 binding protein |
decreases expression |
ISO |
clothianidin results in decreased expression of IL18BP mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 1:156,372,923...156,374,963
Ensembl chr 1:156,372,883...156,374,963
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Il2rg |
interleukin 2 receptor subunit gamma |
increases expression |
ISO |
clothianidin results in increased expression of IL2RG mRNA |
CTD |
PMID:31626844 |
|
NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823
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Immp1l |
inner mitochondrial membrane peptidase subunit 1 |
increases expression |
ISO |
clothianidin results in increased expression of IMMP1L mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:92,385,329...92,450,557
Ensembl chr 3:92,385,379...92,452,313
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Insyn2b |
inhibitory synaptic factor family member 2B |
decreases expression |
ISO |
clothianidin results in decreased expression of FAM196B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:18,916,721...19,023,859
Ensembl chr10:19,003,131...19,022,139
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Irx5 |
iroquois homeobox 5 |
decreases expression |
ISO |
clothianidin results in decreased expression of IRX5 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr19:14,639,052...14,643,911
Ensembl chr19:14,624,225...14,642,318
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Itsn1 |
intersectin 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of ITSN1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:30,978,590...31,160,645
Ensembl chr11:30,978,590...31,160,645
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G |
Jak2 |
Janus kinase 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of JAK2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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G |
Kat6b |
lysine acetyltransferase 6B |
decreases expression |
ISO |
clothianidin results in decreased expression of KAT6B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:2,638,885...2,811,977
Ensembl chr15:2,639,200...2,812,316
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Kcnc4 |
potassium voltage-gated channel subfamily C member 4 |
increases expression |
ISO |
clothianidin results in increased expression of KCNC4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:195,063,967...195,099,233
Ensembl chr 2:195,071,769...195,099,233
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G |
Kcnd3 |
potassium voltage-gated channel subfamily D member 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of KCND3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345
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G |
Kcnk1 |
potassium two pore domain channel subfamily K member 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of KCNK1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr19:53,959,411...53,997,726
Ensembl chr19:53,959,657...53,997,724
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G |
Kcnma1 |
potassium calcium-activated channel subfamily M alpha 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of KCNMA1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198
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Kif7 |
kinesin family member 7 |
increases expression |
ISO |
clothianidin results in increased expression of KIF7 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:133,639,487...133,658,539
Ensembl chr 1:133,640,065...133,658,576
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Kifc3 |
kinesin family member C3 |
increases expression |
ISO |
clothianidin results in increased expression of KIFC3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr19:9,825,208...9,920,371
Ensembl chr19:9,886,693...9,920,451
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G |
Kit |
KIT proto-oncogene receptor tyrosine kinase |
increases expression |
ISO |
clothianidin results in increased expression of KIT mRNA |
CTD |
PMID:31626844 |
|
NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
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G |
Klhdc9 |
kelch domain containing 9 |
decreases expression |
ISO |
clothianidin results in decreased expression of KLHDC9 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr13:83,790,269...83,794,080
Ensembl chr13:83,790,269...83,793,354
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G |
Kpna6 |
karyopherin subunit alpha 6 |
increases expression |
ISO |
clothianidin results in increased expression of KPNA6 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 5:141,988,111...142,021,483
Ensembl chr 5:141,991,568...142,021,120
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Krt28 |
keratin 28 |
increases expression |
ISO |
clothianidin results in increased expression of KRT28 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:84,317,768...84,328,643
Ensembl chr10:84,318,543...84,328,643
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G |
Ksr1 |
kinase suppressor of ras 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of KSR1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:63,961,771...64,098,076
Ensembl chr10:63,961,759...64,098,076
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G |
Ky |
kyphoscoliosis peptidase |
multiple interactions decreases expression |
EXP |
[enilconazole co-treated with clothianidin] results in decreased expression of KY mRNA; [thiacloprid co-treated with clothianidin] results in decreased expression of KY mRNA clothianidin results in decreased expression of KY mRNA |
CTD |
PMID:33426623 |
|
NCBI chr 8:103,086,630...103,126,305
Ensembl chr 8:103,086,630...103,126,024
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G |
L3mbtl1 |
L3MBTL histone methyl-lysine binding protein 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of L3MBTL1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:151,597,903...151,633,657
Ensembl chr 3:151,602,980...151,631,233
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G |
Lgals12 |
galectin 12 |
increases expression |
ISO |
clothianidin results in increased expression of LGALS12 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:204,832,065...204,842,759
Ensembl chr 1:204,832,065...204,842,759
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G |
Lgi4 |
leucine-rich repeat LGI family, member 4 |
increases expression |
ISO |
clothianidin results in increased expression of LGI4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:86,294,539...86,305,909
Ensembl chr 1:86,295,074...86,304,874
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G |
Lim2 |
lens intrinsic membrane protein 2 |
increases expression |
ISO |
clothianidin results in increased expression of LIM2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:93,837,597...93,843,769
Ensembl chr 1:93,837,597...93,843,769
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G |
LOC100911237 |
zinc finger protein 420-like |
increases expression |
ISO |
clothianidin results in increased expression of ZNF502 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:28,884,390...28,908,726
|
|
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LOC102551828 |
uncharacterized LOC102551828 |
decreases expression |
ISO |
clothianidin results in decreased expression of C22ORF31 mRNA |
CTD |
PMID:31626844 |
|
|
|
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LOC290595 |
hypothetical gene supported by AF152002 |
decreases expression |
ISO |
clothianidin results in decreased expression of C10ORF99 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr16:12,868,270...12,875,876
Ensembl chr16:12,868,270...12,875,876
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G |
Lonrf1 |
LON peptidase N-terminal domain and ring finger 1 |
increases expression |
ISO |
clothianidin results in increased expression of LONRF1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr16:55,984,572...56,015,156
Ensembl chr16:55,984,463...56,015,156
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G |
Lox |
lysyl oxidase |
increases expression |
ISO |
clothianidin results in increased expression of LOX mRNA |
CTD |
PMID:29044138 |
|
NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
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|
G |
Lpar1 |
lysophosphatidic acid receptor 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of LPAR1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895
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G |
Lrig1 |
leucine-rich repeats and immunoglobulin-like domains 1 |
increases expression |
ISO |
clothianidin results in increased expression of LRIG1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:127,130,899...127,230,956
Ensembl chr 4:127,130,898...127,231,513
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G |
Lrrc74b |
leucine rich repeat containing 74B |
decreases expression |
ISO |
clothianidin results in decreased expression of LRRC74B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:83,450,588...83,468,906
Ensembl chr11:83,450,624...83,468,922
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G |
Luzp2 |
leucine zipper protein 2 |
increases expression |
ISO |
clothianidin results in increased expression of LUZP2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:105,597,291...105,983,605
Ensembl chr 1:105,597,307...105,981,183
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G |
Lysmd2 |
LysM domain containing 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of LYSMD2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:76,378,984...76,394,395
Ensembl chr 8:76,379,219...76,394,654
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G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation |
ISO |
clothianidin results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:31626844 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
increases phosphorylation |
ISO |
clothianidin results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:31626844 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
|
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G |
Mchr1 |
melanin-concentrating hormone receptor 1 |
increases expression |
ISO |
clothianidin results in increased expression of MCHR1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:112,761,554...112,764,746
Ensembl chr 7:112,761,554...112,764,032
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G |
Megf11 |
multiple EGF-like-domains 11 |
multiple interactions decreases expression |
EXP |
[enilconazole co-treated with clothianidin] results in decreased expression of MEGF11 mRNA; [thiacloprid co-treated with clothianidin] results in decreased expression of MEGF11 mRNA clothianidin results in decreased expression of MEGF11 mRNA |
CTD |
PMID:33426623 |
|
NCBI chr 8:64,892,312...65,218,984
Ensembl chr 8:64,892,387...65,216,061
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G |
Meioc |
meiosis specific with coiled-coil domain |
increases expression |
ISO |
clothianidin results in increased expression of MEIOC mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:87,628,807...87,646,485
Ensembl chr10:87,628,875...87,646,752
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G |
Mettl16 |
methyltransferase like 16 |
increases expression |
ISO |
clothianidin results in increased expression of METTL16 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:59,640,915...59,697,291
Ensembl chr10:59,640,972...59,687,061
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G |
Mettl7a |
methyltransferase like 7A |
decreases expression |
ISO |
clothianidin results in decreased expression of METTL7A mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 7:131,452,099...131,460,154
Ensembl chr 7:131,451,641...131,460,154
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G |
Mical1 |
microtubule associated monooxygenase, calponin and LIM domain containing 1 |
increases expression |
ISO |
clothianidin results in increased expression of MICAL1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr20:44,974,137...44,986,089
Ensembl chr20:44,974,138...44,986,089
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G |
Micall2 |
MICAL-like 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of MICALL2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr12:14,899,151...14,927,949
Ensembl chr12:14,899,157...14,927,946
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G |
Mlana |
melan-A |
increases expression |
ISO |
clothianidin results in increased expression of MLANA mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:227,469,537...227,483,343
Ensembl chr 1:227,469,537...227,483,343
|
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G |
Mme |
membrane metallo-endopeptidase |
multiple interactions increases expression |
EXP |
[enilconazole co-treated with clothianidin] results in increased expression of MME mRNA; [thiacloprid co-treated with clothianidin] results in increased expression of MME mRNA clothianidin results in increased expression of MME mRNA |
CTD |
PMID:33426623 |
|
NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792
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G |
Mmp10 |
matrix metallopeptidase 10 |
increases expression |
ISO |
clothianidin results in increased expression of MMP10 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
|
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G |
Ms4a2 |
membrane spanning 4-domains A2 |
decreases expression |
ISO |
clothianidin results in decreased expression of MS4A2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 1:208,440,179...208,448,716
Ensembl chr 1:208,440,361...208,448,310
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|
G |
Mss51 |
MSS51 mitochondrial translational activator |
decreases expression |
ISO |
clothianidin results in decreased expression of MSS51 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr15:3,805,240...3,819,385
Ensembl chr15:3,807,516...3,819,385
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G |
Mtg1 |
mitochondrial ribosome-associated GTPase 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of MTG1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 1:194,931,543...194,944,278
Ensembl chr 1:194,931,531...194,944,277
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G |
Myl4 |
myosin, light chain 4 |
decreases expression |
ISO |
clothianidin results in decreased expression of MYL4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363
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G |
Myl6 |
myosin light chain 6 |
decreases expression |
ISO |
clothianidin results in decreased expression of MYL6 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:910,764...914,062
Ensembl chr 7:910,774...933,791
|
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G |
Mylpf |
myosin light chain, phosphorylatable, fast skeletal muscle |
decreases expression |
ISO |
clothianidin results in decreased expression of MYL11 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:181,829,703...181,832,546
Ensembl chr 1:181,829,743...181,832,545
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G |
Myo3b |
myosin IIIB |
increases expression |
ISO |
clothianidin results in increased expression of MYO3B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:54,873,704...55,226,189
Ensembl chr 3:54,820,251...55,227,373
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|
G |
Myorg |
myogenesis regulating glycosidase |
increases expression |
ISO |
clothianidin results in increased expression of MYORG mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 5:56,654,257...56,664,467
Ensembl chr 5:56,648,643...56,664,440
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G |
Myt1l |
myelin transcription factor 1-like |
increases expression |
ISO |
clothianidin results in increased expression of MYT1L mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:46,164,742...46,564,234
Ensembl chr 6:46,428,150...46,561,671
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|
G |
N4bp2l1 |
NEDD4 binding protein 2-like 1 |
increases expression |
ISO |
clothianidin results in increased expression of N4BP2L1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr12:102,572...128,352
Ensembl chr12:102,573...127,257
|
|
G |
Nadsyn1 |
NAD synthetase 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of NADSYN1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:198,981,559...199,009,806
Ensembl chr 1:198,981,604...199,009,869
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|
G |
Nasp |
nuclear autoantigenic sperm protein |
decreases expression |
ISO |
clothianidin results in decreased expression of NASP mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 5:130,057,363...130,083,003
Ensembl chr 5:130,057,363...130,082,928
|
|
G |
Ndufa10 |
NADH:ubiquinone oxidoreductase subunit A10 |
increases expression |
ISO |
clothianidin results in increased expression of NDUFA10 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 9:93,007,034...93,041,825
Ensembl chr 9:93,007,042...93,042,560
|
|
G |
Neurod4 |
neuronal differentiation 4 |
decreases expression |
ISO |
clothianidin results in decreased expression of NEUROD4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:7,090,048...7,102,018
Ensembl chr 7:7,090,045...7,102,030
|
|
G |
Ngef |
neuronal guanine nucleotide exchange factor |
increases expression |
ISO |
clothianidin results in increased expression of NGEF mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 9:88,146,956...88,244,454
Ensembl chr 9:88,146,956...88,244,914
|
|
G |
Ngfr |
nerve growth factor receptor |
increases expression |
ISO |
clothianidin results in increased expression of NGFR mRNA |
CTD |
PMID:29044138 |
|
NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
|
|
G |
Nos2 |
nitric oxide synthase 2 |
increases expression |
ISO |
clothianidin results in increased expression of NOS2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
|
|
G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
decreases expression multiple interactions |
ISO |
clothianidin results in decreased expression of NR0B2 mRNA [clothianidin co-treated with enilconazole] results in decreased expression of NR0B2 mRNA |
CTD |
PMID:32201337 |
|
NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
|
|
G |
Ntn4 |
netrin 4 |
decreases expression |
ISO |
clothianidin results in decreased expression of NTN4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:28,186,611...28,300,390
Ensembl chr 7:28,186,611...28,300,390
|
|
G |
Nts |
neurotensin |
decreases expression |
ISO |
clothianidin results in decreased expression of NTS mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423
|
|
G |
Nxnl2 |
nucleoredoxin-like 2 |
increases expression |
ISO |
clothianidin results in increased expression of NXNL2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr17:14,031,151...14,035,897
Ensembl chr17:14,031,153...14,036,189
|
|
G |
Nxph2 |
neurexophilin 2 |
increases expression |
ISO |
clothianidin results in increased expression of NXPH2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:5,986,175...5,988,525
Ensembl chr 3:5,756,621...5,987,008
|
|
G |
Ocrl |
OCRL, inositol polyphosphate-5-phosphatase |
decreases expression |
ISO |
clothianidin results in decreased expression of OCRL mRNA |
CTD |
PMID:31626844 |
|
NCBI chr X:127,089,508...127,140,362
Ensembl chr X:127,089,590...127,140,362
|
|
G |
Olr59 |
olfactory receptor 59 |
increases expression |
ISO |
clothianidin results in increased expression of OR51E2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:157,193,051...157,227,707
Ensembl chr 1:157,193,080...157,211,179
|
|
G |
Otud6b |
OTU deubiquitinase 6B |
increases expression |
ISO |
clothianidin results in increased expression of OTUD6B mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 5:28,181,992...28,214,486
Ensembl chr 5:28,023,594...28,214,334
|
|
G |
Padi4 |
peptidyl arginine deiminase 4 |
increases expression |
ISO |
clothianidin results in increased expression of PADI4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 5:153,041,351...153,074,412
Ensembl chr 5:153,041,352...153,074,362
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G |
Pak5 |
p21 (RAC1) activated kinase 5 |
decreases expression |
ISO |
clothianidin results in decreased expression of PAK5 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:123,395,678...123,703,967
Ensembl chr 3:123,396,497...123,703,930
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G |
Paqr8 |
progestin and adipoQ receptor family member 8 |
decreases expression |
ISO |
clothianidin results in decreased expression of PAQR8 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 9:23,312,521...23,362,175
Ensembl chr 9:23,312,585...23,362,340
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G |
Pbld1 |
phenazine biosynthesis-like protein domain containing 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of PBLD mRNA |
CTD |
PMID:31626844 |
|
NCBI chr20:25,551,274...25,566,543
Ensembl chr20:25,551,275...25,565,614
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G |
Pcca |
propionyl-CoA carboxylase subunit alpha |
decreases expression |
ISO |
clothianidin results in decreased expression of PCCA mRNA |
CTD |
PMID:32201337 |
|
NCBI chr15:99,627,955...99,969,555
Ensembl chr15:99,627,982...99,968,266
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G |
Pcsk1 |
proprotein convertase subtilisin/kexin type 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of PCSK1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434
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G |
Pde10a |
phosphodiesterase 10A |
decreases expression |
ISO |
clothianidin results in decreased expression of PDE10A mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:51,770,132...52,216,563
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G |
Pde1c |
phosphodiesterase 1C |
increases expression |
ISO |
clothianidin results in increased expression of PDE1C mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:85,300,858...85,777,948
Ensembl chr 4:85,300,858...85,863,219
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G |
Pde4dip |
phosphodiesterase 4D interacting protein |
increases expression |
ISO |
clothianidin results in increased expression of PDE4DIP mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:185,293,236...185,490,100
Ensembl chr 2:185,293,214...185,468,379
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G |
Pdzd7 |
PDZ domain containing 7 |
decreases expression |
ISO |
clothianidin results in decreased expression of PDZD7 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 1:243,888,295...243,907,778
Ensembl chr 1:243,888,281...243,906,839
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G |
Peli2 |
pellino E3 ubiquitin protein ligase family member 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of PELI2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:21,393,262...21,537,737
Ensembl chr15:21,393,262...21,535,106
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G |
Pheta2 |
PH domain containing endocytic trafficking adaptor 2 |
increases expression |
ISO |
clothianidin results in increased expression of FAM109B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:113,855,437...113,861,910
Ensembl chr 7:113,857,249...113,861,871
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|
G |
Pik3c2b |
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
decreases expression |
ISO |
clothianidin results in decreased expression of PIK3C2B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr13:44,494,673...44,555,663
Ensembl chr13:44,495,050...44,555,612
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G |
Pip5k1c |
phosphatidylinositol-4-phosphate 5-kinase type 1 gamma |
decreases expression |
ISO |
clothianidin results in decreased expression of PIP5K1C mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:8,397,406...8,426,030
Ensembl chr 7:8,397,406...8,425,988
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G |
Pip5kl1 |
phosphatidylinositol-4-phosphate 5-kinase-like 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of PIP5KL1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 3:15,860,493...15,869,264
Ensembl chr 3:15,855,946...15,869,165
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G |
Pla2g2a |
phospholipase A2 group IIA |
increases expression |
ISO |
clothianidin results in increased expression of PLA2G2A mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
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G |
Plbd1 |
phospholipase B domain containing 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of PLBD1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:169,472,983...169,529,277
Ensembl chr 4:169,472,983...169,529,277
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G |
Plcd1 |
phospholipase C, delta 1 |
increases expression |
ISO |
clothianidin results in increased expression of PLCD1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:118,795,196...118,818,186
Ensembl chr 8:118,795,201...118,818,186
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G |
Plcd3 |
phospholipase C, delta 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of PLCD3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:88,026,707...88,048,080
Ensembl chr10:88,026,740...88,048,296
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G |
Plcl1 |
phospholipase C-like 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of PLCL1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 9:56,901,573...57,238,782
Ensembl chr 9:56,901,534...57,238,782
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|
G |
Pllp |
plasmolipin |
increases expression |
ISO |
clothianidin results in increased expression of PLLP mRNA |
CTD |
PMID:31626844 |
|
NCBI chr19:10,315,104...10,335,892
Ensembl chr19:10,315,104...10,335,892
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G |
Pnpla1 |
patatin-like phospholipase domain containing 1 |
increases expression |
ISO |
clothianidin results in increased expression of PNPLA1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr20:6,918,446...6,951,650
Ensembl chr20:6,917,931...6,952,375
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G |
Polr2m |
RNA polymerase II subunit M |
decreases expression |
ISO |
clothianidin results in decreased expression of POLR2M mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:72,131,992...72,139,423
Ensembl chr 8:72,131,530...72,243,036
|
|
G |
Ppp1r3c |
protein phosphatase 1, regulatory subunit 3C |
increases expression |
ISO |
clothianidin results in increased expression of PPP1R3C mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961
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|
G |
Ppp3cc |
protein phosphatase 3 catalytic subunit gamma |
increases expression |
ISO |
clothianidin results in increased expression of PPP3CC mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:45,289,917...45,362,012
Ensembl chr15:45,290,373...45,361,832
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|
G |
Prg3 |
proteoglycan 3, pro eosinophil major basic protein 2 |
increases expression |
ISO |
clothianidin results in increased expression of PRG3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:70,071,970...70,078,103
Ensembl chr 3:70,072,497...70,078,102
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|
G |
Prlr |
prolactin receptor |
decreases expression |
ISO |
clothianidin results in decreased expression of PRLR mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718
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|
G |
Prnd |
prion like protein doppel |
increases expression |
ISO |
clothianidin results in increased expression of PRND mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:119,213,402...119,218,742
Ensembl chr 3:119,213,429...119,218,745
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|
G |
Prodh2 |
proline dehydrogenase 2 |
increases expression |
ISO |
clothianidin results in increased expression of PRODH2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:85,753,558...85,767,165
Ensembl chr 1:85,753,644...85,767,162
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|
G |
Prr5l |
proline rich 5 like |
increases expression |
ISO |
clothianidin results in increased expression of PRR5L mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:88,001,951...88,173,532
Ensembl chr 3:88,003,617...88,082,763
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|
G |
Prxl2b |
peroxiredoxin like 2B |
decreases expression |
ISO |
clothianidin results in decreased expression of PRXL2B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 5:165,462,610...165,465,213
|
|
G |
Psmc6 |
proteasome 26S subunit, ATPase 6 |
decreases expression |
ISO |
clothianidin results in decreased expression of PSMC6 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055
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|
G |
Ptgfr |
prostaglandin F receptor |
decreases expression |
ISO |
clothianidin results in decreased expression of PTGFR mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:240,731,185...240,766,674
Ensembl chr 2:240,733,375...240,765,650
|
|
G |
Ptpn3 |
protein tyrosine phosphatase, non-receptor type 3 |
increases expression |
ISO |
clothianidin results in increased expression of PTPN3 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 5:71,908,520...72,027,323
Ensembl chr 5:71,911,135...72,065,443
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|
G |
Ptprb |
protein tyrosine phosphatase, receptor type, B |
decreases expression |
ISO |
clothianidin results in decreased expression of PTPRB mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:51,953,375...52,034,751
Ensembl chr 7:51,930,015...52,034,748
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|
G |
Ptpro |
protein tyrosine phosphatase, receptor type, O |
decreases expression |
ISO |
clothianidin results in decreased expression of PTPRO mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 4:170,164,071...170,374,790
Ensembl chr 4:170,164,431...170,374,771
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|
G |
Qpct |
glutaminyl-peptide cyclotransferase |
increases expression |
ISO |
clothianidin results in increased expression of QPCT mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:15,964,656...15,996,925
Ensembl chr 6:15,964,657...15,996,711
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|
G |
Rag1 |
recombination activating 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of RAG1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:87,917,061...87,928,158
Ensembl chr 3:87,917,004...87,928,291
|
|
G |
Rapgefl1 |
Rap guanine nucleotide exchange factor like 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of RAPGEFL1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr10:83,793,711...83,810,373
Ensembl chr10:83,793,694...83,810,371
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|
G |
Rbm26 |
RNA binding motif protein 26 |
decreases expression |
ISO |
clothianidin results in decreased expression of RBM26 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:81,884,783...81,964,245
Ensembl chr15:81,887,219...81,964,118
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|
G |
Rbms1 |
RNA binding motif, single stranded interacting protein 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of RBMS1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:45,195,828...45,420,406
Ensembl chr 3:45,197,972...45,420,376
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|
G |
Reg3g |
regenerating family member 3 gamma |
increases expression |
ISO |
clothianidin results in increased expression of REG3G mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:110,922,805...110,927,803
Ensembl chr 4:110,924,168...110,926,723
|
|
G |
Rfesd |
Rieske (Fe-S) domain containing |
decreases expression |
ISO |
clothianidin results in decreased expression of RFESD mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:5,495,067...5,521,095
Ensembl chr 2:5,505,756...5,522,449
|
|
G |
RGD1306227 |
similar to 4833420G17Rik protein |
increases expression |
ISO |
clothianidin results in increased expression of C5ORF34 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 2:51,553,223...51,577,090
Ensembl chr 2:51,555,432...51,577,085
|
|
G |
RGD1309651 |
similar to 1190005I06Rik protein |
decreases expression |
ISO |
clothianidin results in decreased expression of C16ORF74 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr19:48,660,288...48,686,569
Ensembl chr19:48,660,288...48,686,349
|
|
G |
RGD1559804 |
similar to hypothetical protein 4930474N05 |
increases expression |
ISO |
clothianidin results in increased expression of CDRT15L2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr16:11,224,803...11,231,972
Ensembl chr16:11,122,718...11,158,623
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|
G |
RGD1563060 |
similar to AVLV472 |
increases expression |
ISO |
clothianidin results in increased expression of C5ORF46 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr18:35,948,402...35,969,502
Ensembl chr18:35,948,402...35,969,502
|
|
G |
RGD1564149 |
similar to Protein C21orf58 |
decreases expression |
ISO |
clothianidin results in decreased expression of C21ORF58 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr20:12,167,279...12,188,665
Ensembl chr20:12,175,442...12,187,017
|
|
G |
Riiad1 |
regulatory subunit of type II PKA R-subunit domain containing 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of RIIAD1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:182,099,924...182,110,544
Ensembl chr 2:182,101,795...182,110,319
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|
G |
Rnd1 |
Rho family GTPase 1 |
increases expression |
ISO |
clothianidin results in increased expression of RND1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 7:129,821,311...129,828,385
Ensembl chr 7:129,821,311...129,828,399
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|
G |
Rp1l1 |
RP1 like 1 |
increases expression |
ISO |
clothianidin results in increased expression of RP1L1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:38,259,595...38,271,269
Ensembl chr15:38,259,928...38,270,316
|
|
G |
Rps29 |
ribosomal protein S29 |
increases expression |
ISO |
clothianidin results in increased expression of RPS29 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:87,635,229...87,636,605
Ensembl chr 6:87,635,230...87,636,636
|
|
G |
RT1-Bb |
RT1 class II, locus Bb |
increases expression |
ISO |
clothianidin results in increased expression of HLA-DQB1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
|
|
G |
S100a5 |
S100 calcium binding protein A5 |
decreases expression |
ISO |
clothianidin results in decreased expression of S100A5 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:176,095,332...176,099,546
Ensembl chr 2:176,097,539...176,099,546
|
|
G |
Sash3 |
SAM and SH3 domain containing 3 |
increases expression |
ISO |
clothianidin results in increased expression of SASH3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr X:127,326,815...127,341,521
Ensembl chr X:127,326,859...127,341,519
|
|
G |
Scn7a |
sodium voltage-gated channel alpha subunit 7 |
decreases expression |
ISO |
clothianidin results in decreased expression of SCN7A mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:51,335,841...51,438,308
Ensembl chr 3:51,335,841...51,438,256
|
|
G |
Scnn1b |
sodium channel epithelial 1 subunit beta |
increases expression |
ISO |
clothianidin results in increased expression of SCNN1B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451
|
|
G |
Sema3f |
semaphorin 3F |
decreases expression |
ISO |
clothianidin results in decreased expression of SEMA3F mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:108,357,629...108,387,083
Ensembl chr 8:108,357,629...108,387,083
|
|
G |
Serp1 |
stress-associated endoplasmic reticulum protein 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of SERP1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:142,757,254...142,761,243
Ensembl chr 2:142,757,270...142,761,116
|
|
G |
Serpinc1 |
serpin family C member 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of SERPINC1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
|
|
G |
Serpine1 |
serpin family E member 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of SERPINE1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
|
|
G |
Sgcd |
sarcoglycan, delta |
increases expression |
ISO |
clothianidin results in increased expression of SGCD mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:31,346,480...32,328,364
Ensembl chr10:31,280,511...31,724,840
|
|
G |
Sgk2 |
serum/glucocorticoid regulated kinase 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of SGK2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480
|
|
G |
Sh3tc1 |
SH3 domain and tetratricopeptide repeats 1 |
increases expression |
ISO |
clothianidin results in increased expression of SH3TC1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr14:75,005,691...75,050,001
Ensembl chr14:75,016,875...75,049,995
|
|
G |
Sipa1l2 |
signal-induced proliferation-associated 1 like 2 |
increases expression |
ISO |
clothianidin results in increased expression of SIPA1L2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr19:53,389,792...53,540,466
Ensembl chr19:53,389,805...53,540,428
|
|
G |
Slc14a1 |
solute carrier family 14 member 1 (Kidd blood group) |
decreases expression |
ISO |
clothianidin results in decreased expression of SLC14A1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr18:71,565,453...71,608,807
Ensembl chr18:71,565,454...71,595,146
|
|
G |
Slc17a7 |
solute carrier family 17 member 7 |
decreases expression |
ISO |
clothianidin results in decreased expression of SLC17A7 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588
|
|
G |
Slc22a2 |
solute carrier family 22 member 2 |
decreases activity |
ISO |
clothianidin results in decreased activity of SLC22A2 protein |
CTD |
PMID:31364238 |
|
NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
|
|
G |
Slc22a6 |
solute carrier family 22 member 6 |
decreases activity |
ISO |
clothianidin results in decreased activity of SLC22A6 protein |
CTD |
PMID:31364238 |
|
NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
|
|
G |
Slc22a8 |
solute carrier family 22 member 8 |
decreases activity |
ISO |
clothianidin results in decreased activity of SLC22A8 protein |
CTD |
PMID:31364238 |
|
NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
|
|
G |
Slc28a1 |
solute carrier family 28 member 1 |
increases expression |
ISO |
clothianidin results in increased expression of SLC28A1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:135,079,375...135,122,791
Ensembl chr 1:135,081,385...135,122,464
|
|
G |
Slc38a9 |
solute carrier family 38, member 9 |
decreases expression |
ISO |
clothianidin results in decreased expression of SLC38A9 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:44,291,637...44,374,897
Ensembl chr 2:44,291,989...44,368,955
|
|
G |
Slc45a2 |
solute carrier family 45, member 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of SLC45A2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:59,963,599...59,996,408
Ensembl chr 2:59,963,706...59,996,317
|
|
G |
Slc47a2 |
solute carrier family 47 member 2 |
decreases activity |
ISO |
clothianidin results in decreased activity of SLC47A2 protein |
CTD |
PMID:31364238 |
|
NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904
|
|
G |
Slc48a1 |
solute carrier family 48 member 1 |
increases expression |
ISO |
clothianidin results in increased expression of SLC48A1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:128,915,136...128,923,929
Ensembl chr 7:128,915,195...128,923,024
|
|
G |
Slc6a1 |
solute carrier family 6 member 1 |
decreases expression multiple interactions |
EXP |
clothianidin results in decreased expression of SLC6A1 mRNA [enilconazole co-treated with clothianidin] results in decreased expression of SLC6A1 mRNA; [thiacloprid co-treated with clothianidin] results in decreased expression of SLC6A1 mRNA |
CTD |
PMID:33426623 |
|
NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293
|
|
G |
Slco1c1 |
solute carrier organic anion transporter family, member 1c1 |
increases expression |
ISO |
clothianidin results in increased expression of SLCO1C1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:174,466,621...174,513,290
Ensembl chr 4:174,466,631...174,513,289
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G |
Sorbs1 |
sorbin and SH3 domain containing 1 |
increases expression |
ISO |
clothianidin results in increased expression of SORBS1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:239,107,882...239,330,276
Ensembl chr 1:239,108,777...239,330,169
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|
G |
Spata3 |
spermatogenesis associated 3 |
increases expression |
ISO |
clothianidin results in increased expression of SPATA3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 9:86,660,352...86,672,272
Ensembl chr 9:86,659,784...86,672,272
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G |
Spire2 |
spire-type actin nucleation factor 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of SPIRE2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr19:51,373,368...51,411,920
Ensembl chr19:51,373,228...51,411,920
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G |
Srd5a2 |
steroid 5 alpha-reductase 2 |
increases expression |
ISO |
clothianidin results in increased expression of SRD5A2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112
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G |
Sspo |
SCO-spondin |
decreases expression |
ISO |
clothianidin results in decreased expression of SSPOP mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 4:77,394,915...77,450,526
Ensembl chr 4:77,397,059...77,450,412
|
|
G |
Stac2 |
SH3 and cysteine rich domain 2 |
increases expression |
ISO |
clothianidin results in increased expression of STAC2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:83,032,417...83,048,260
Ensembl chr10:83,032,417...83,048,260
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G |
Steap2 |
STEAP2 metalloreductase |
increases expression |
ISO |
clothianidin results in increased expression of STEAP2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:28,347,769...28,368,177
Ensembl chr 4:28,348,362...28,375,791
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|
G |
Susd4 |
sushi domain containing 4 |
increases expression |
ISO |
clothianidin results in increased expression of SUSD4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr13:94,455,180...94,577,773
Ensembl chr13:94,455,165...94,577,750
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|
G |
Sycp2 |
synaptonemal complex protein 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of SYCP2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 3:165,431,715...165,502,134
Ensembl chr 3:165,436,331...165,498,789
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|
G |
Synpo |
synaptopodin |
decreases expression |
ISO |
clothianidin results in decreased expression of SYNPO mRNA |
CTD |
PMID:29044138 |
|
NCBI chr18:54,048,299...54,106,388
Ensembl chr18:54,026,152...54,102,126
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|
G |
Tacr1 |
tachykinin receptor 1 |
increases expression |
ISO |
clothianidin results in increased expression of TACR1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733
|
|
G |
Tafa2 |
TAFA chemokine like family member 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of FAM19A2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:58,942,598...59,418,640
Ensembl chr 7:58,942,610...59,417,299
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|
G |
Tafa5 |
TAFA chemokine like family member 5 |
increases expression |
ISO |
clothianidin results in increased expression of FAM19A5 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:118,613,731...118,835,016
Ensembl chr 7:118,613,889...118,834,353
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|
G |
Tbx2 |
T-box transcription factor 2 |
increases expression |
ISO |
clothianidin results in increased expression of TBX2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529
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|
G |
Tcp10b |
t-complex protein 10b |
increases expression |
ISO |
clothianidin results in increased expression of TCP10L2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:52,937,823...52,961,307
Ensembl chr 1:52,937,917...52,961,307
|
|
G |
Tecpr1 |
tectonin beta-propeller repeat containing 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of TECPR1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr12:10,391,587...10,420,462
Ensembl chr12:10,391,696...10,419,611
|
|
G |
Tef |
TEF transcription factor, PAR bZIP family member |
increases expression |
ISO |
clothianidin results in increased expression of TEF mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:113,317,191...113,341,783
Ensembl chr 7:113,317,283...113,341,783
|
|
G |
Tgfbi |
transforming growth factor, beta induced |
increases expression |
ISO |
clothianidin results in increased expression of TGFBI mRNA |
CTD |
PMID:31626844 |
|
NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240
|
|
G |
Tgm5 |
transglutaminase 5 |
decreases expression |
ISO |
clothianidin results in decreased expression of TGM5 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 3:108,008,087...108,014,813 NCBI chr 3:108,028,742...108,048,946
Ensembl chr 3:108,008,143...108,043,976
|
|
G |
Tifa |
TRAF-interacting protein with forkhead-associated domain |
increases expression |
ISO |
clothianidin results in increased expression of TIFA mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:216,257,926...216,267,635
Ensembl chr 2:216,234,774...216,267,841
|
|
G |
Tlcd4 |
TLC domain containing 4 |
increases expression |
ISO |
clothianidin results in increased expression of TLCD4 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 2:209,284,873...209,360,156
Ensembl chr 2:209,289,732...209,341,353
|
|
G |
Tlx3 |
T-cell leukemia, homeobox 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of TLX3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:17,789,706...17,792,207
Ensembl chr10:17,790,053...17,792,207
|
|
G |
Tmem273 |
transmembrane protein 273 |
increases expression |
ISO |
clothianidin results in increased expression of C10ORF128 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr16:8,049,565...8,081,981
Ensembl chr16:8,049,669...8,081,981
|
|
G |
Tmem38a |
transmembrane protein 38a |
decreases expression |
ISO |
clothianidin results in decreased expression of TMEM38A mRNA |
CTD |
PMID:29044138 |
|
NCBI chr16:17,258,160...17,274,204
Ensembl chr16:17,258,164...17,273,415
|
|
G |
Tmem71 |
transmembrane protein 71 |
decreases expression |
ISO |
clothianidin results in decreased expression of TMEM71 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:98,276,975...98,323,161
Ensembl chr 7:98,276,975...98,315,858
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
clothianidin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; clothianidin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] |
CTD |
PMID:29044138 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
|
|
G |
Tnfrsf11b |
TNF receptor superfamily member 11B |
decreases expression |
ISO |
clothianidin results in decreased expression of TNFRSF11B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
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|
G |
Tnxb |
tenascin XB |
decreases expression |
ISO |
clothianidin results in decreased expression of TNXB mRNA |
CTD |
PMID:29044138 |
|
|
|
G |
Tpm1 |
tropomyosin 1 |
increases expression |
ISO |
clothianidin results in increased expression of TPM1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
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|
G |
Traf4 |
Tnf receptor associated factor 4 |
increases expression |
ISO |
clothianidin results in increased expression of TRAF4 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr10:63,054,169...63,060,284
Ensembl chr10:63,054,181...63,060,284
|
|
G |
Traf6 |
TNF receptor associated factor 6 |
decreases expression |
ISO |
clothianidin results in decreased expression of TRAF6 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
|
|
G |
Trappc4 |
trafficking protein particle complex subunit 4 |
increases expression |
ISO |
clothianidin results in increased expression of TRAPPC4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:44,729,458...44,733,285
Ensembl chr 8:44,725,331...44,733,491
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|
G |
Trim37 |
tripartite motif-containing 37 |
decreases expression |
ISO |
clothianidin results in decreased expression of TRIM37 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:71,943,384...72,075,567
Ensembl chr10:71,943,375...72,075,558
|
|
G |
Trmt44 |
tRNA methyltransferase 44 |
increases expression |
ISO |
clothianidin results in increased expression of TRMT44 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr14:75,175,331...75,204,291
Ensembl chr14:75,182,029...75,200,147
|
|
G |
Tssk6 |
testis-specific serine kinase 6 |
decreases expression |
ISO |
clothianidin results in decreased expression of TSSK6 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr16:19,523,626...19,526,074
Ensembl chr16:19,517,334...19,526,090
|
|
G |
Ttc28 |
tetratricopeptide repeat domain 28 |
decreases expression |
ISO |
clothianidin results in decreased expression of TTC28 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr12:45,342,986...45,783,968
Ensembl chr12:45,345,399...45,783,547
|
|
G |
Ttc30b |
tetratricopeptide repeat domain 30B |
decreases expression |
ISO |
clothianidin results in decreased expression of TTC30B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:60,855,809...60,858,380
Ensembl chr 3:60,855,575...60,858,389
|
|
G |
Ttc33 |
tetratricopeptide repeat domain 33 |
decreases expression |
ISO |
clothianidin results in decreased expression of TTC33 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:54,279,906...54,326,851
Ensembl chr 2:54,279,997...54,323,871
|
|
G |
Ttc8 |
tetratricopeptide repeat domain 8 |
decreases expression |
ISO |
clothianidin results in decreased expression of TTC8 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:118,198,186...118,252,422
Ensembl chr 6:118,198,201...118,252,418
|
|
G |
Tubgcp3 |
tubulin, gamma complex associated protein 3 |
increases expression |
ISO |
clothianidin results in increased expression of TUBGCP3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr16:76,851,859...76,912,499
Ensembl chr16:76,851,810...76,912,499
|
|
G |
Txndc2 |
thioredoxin domain containing 2 |
increases expression |
ISO |
clothianidin results in increased expression of TXNDC2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 9:105,230,575...105,235,131
Ensembl chr 9:105,230,578...105,235,126
|
|
G |
Ubap1l |
ubiquitin associated protein 1-like |
decreases expression increases expression |
ISO |
clothianidin results in decreased expression of UBAP1L mRNA clothianidin results in increased expression of UBAP1L mRNA |
CTD |
PMID:29044138 PMID:31626844 |
|
NCBI chr 8:65,877,488...65,897,593
Ensembl chr 8:65,884,729...65,897,593
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|
G |
Unc119b |
unc-119 lipid binding chaperone B |
increases expression |
ISO |
clothianidin results in increased expression of UNC119B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr12:41,478,808...41,491,432
Ensembl chr12:41,478,808...41,491,432
|
|
G |
Usp43 |
ubiquitin specific peptidase 43 |
decreases expression |
ISO |
clothianidin results in decreased expression of USP43 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:52,549,200...52,611,084
Ensembl chr10:52,548,963...52,611,533
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|
G |
Utrn |
utrophin |
decreases expression |
ISO |
clothianidin results in decreased expression of UTRN mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:6,720,854...7,224,313
Ensembl chr 1:6,722,594...7,224,313
|
|
G |
Vamp8 |
vesicle-associated membrane protein 8 |
increases expression |
ISO |
clothianidin results in increased expression of VAMP8 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897
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|
G |
Vegfd |
vascular endothelial growth factor D |
decreases expression |
ISO |
clothianidin results in decreased expression of VEGFD mRNA |
CTD |
PMID:31626844 |
|
NCBI chr X:30,073,122...30,108,413
Ensembl chr X:30,074,163...30,108,295
|
|
G |
Vps8 |
VPS8 subunit of CORVET complex |
decreases expression |
ISO |
clothianidin results in decreased expression of VPS8 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:79,402,236...79,634,234
Ensembl chr11:79,402,239...79,634,133
|
|
G |
Washc4 |
WASH complex subunit 4 |
increases expression |
ISO |
clothianidin results in increased expression of WASHC4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:20,187,905...20,240,228
Ensembl chr 7:20,187,922...20,240,226
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|
G |
Whrn |
whirlin |
increases expression |
ISO |
clothianidin results in increased expression of WHRN mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 5:76,828,308...76,911,945
Ensembl chr 5:76,828,301...76,912,223
|
|
G |
Ypel2 |
yippee-like 2 |
increases expression |
ISO |
clothianidin results in increased expression of YPEL2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:71,746,308...71,803,855
Ensembl chr10:71,746,311...71,803,911
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|
G |
Ypel3 |
yippee-like 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of YPEL3 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 1:181,384,385...181,387,706
Ensembl chr 1:181,384,357...181,387,705
|
|
G |
Zbtb45 |
zinc finger and BTB domain containing 45 |
decreases expression |
ISO |
clothianidin results in decreased expression of ZBTB45 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:73,634,895...73,639,802
Ensembl chr 1:73,635,448...73,639,556
|
|
G |
Zcchc13 |
zinc finger CCHC-type containing 13 |
decreases expression |
ISO |
clothianidin results in decreased expression of ZCCHC13 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr X:68,643,554...68,644,646
Ensembl chr X:68,643,549...68,665,131
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|
G |
Zfp18 |
zinc finger protein 18 |
decreases expression |
ISO |
clothianidin results in decreased expression of ZNF18 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:50,473,428...50,495,707
Ensembl chr10:50,473,483...50,495,706
|
|
G |
Zfp219 |
zinc finger protein 219 |
decreases expression |
ISO |
clothianidin results in decreased expression of ZNF219 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr15:24,695,831...24,710,039
Ensembl chr15:24,695,837...24,710,030
|
|
G |
Zfp467 |
zinc finger protein 467 |
increases expression |
ISO |
clothianidin results in increased expression of ZNF467 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:77,385,752...77,394,709
Ensembl chr 4:77,385,758...77,392,229
|
|
G |
Zfp521 |
zinc finger protein 521 |
decreases expression |
ISO |
clothianidin results in decreased expression of ZNF521 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr18:4,775,952...5,068,592
Ensembl chr18:4,787,295...5,068,458
|
|
G |
Zfp653 |
zinc finger protein 653 |
decreases expression |
ISO |
clothianidin results in decreased expression of ZNF653 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:20,586,563...20,605,439
Ensembl chr 8:20,586,563...20,604,864
|
|
G |
Zfp865 |
zinc finger protein 865 |
increases expression |
ISO |
clothianidin results in increased expression of ZNF784 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:68,805,302...68,809,780
Ensembl chr 1:68,805,302...68,809,780
|
|
G |
Zkscan7 |
zinc finger with KRAB and SCAN domains 7 |
increases expression |
ISO |
clothianidin results in increased expression of ZKSCAN7 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:122,501,938...122,519,600
Ensembl chr 8:122,502,218...122,519,600
|
|
G |
Zswim4 |
zinc finger, SWIM-type containing 4 |
decreases expression |
ISO |
clothianidin results in decreased expression of ZSWIM4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr19:23,927,845...23,952,970
Ensembl chr19:23,927,845...23,952,970
|
|
|
G |
Atf3 |
activating transcription factor 3 |
multiple interactions |
ISO |
[Rifampin co-treated with Cobicistat] results in increased expression of ATF3 mRNA |
CTD |
PMID:33629115 |
|
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
[Rifampin co-treated with Cobicistat] results in increased expression of BAX mRNA |
CTD |
PMID:33629115 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
|
|
G |
Cbr3 |
carbonyl reductase 3 |
multiple interactions |
ISO |
[Rifampin co-treated with Cobicistat] results in increased expression of CBR3 mRNA |
CTD |
PMID:33629115 |
|
NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
|
|
G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions |
ISO |
[[Rifampin results in increased activity of NR1I2 protein] which results in increased activity of CYP3A4 protein] which results in increased metabolism of and results in increased activity of and results in increased susceptibility to Cobicistat |
CTD |
PMID:33629115 |
|
NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
|
|
G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions |
ISO |
[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Cobicistat] results in increased expression of DDIT3 mRNA; [Rifampin co-treated with Cobicistat] results in increased expression of DDIT3 mRNA |
CTD |
PMID:33629115 |
|
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
|
|
G |
Gpx2 |
glutathione peroxidase 2 |
multiple interactions |
ISO |
[Rifampin co-treated with Cobicistat] results in increased expression of GPX2 mRNA |
CTD |
PMID:33629115 |
|
NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
|
|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
ISO |
[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Cobicistat] results in increased expression of HSPA5 mRNA; [Rifampin co-treated with Cobicistat] results in increased expression of HSPA5 mRNA |
CTD |
PMID:33629115 |
|
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
|
|
G |
Ngfr |
nerve growth factor receptor |
multiple interactions |
ISO |
[Rifampin co-treated with Cobicistat] results in increased expression of TNFRSF10B mRNA |
CTD |
PMID:33629115 |
|
NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
|
|
G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions |
ISO |
[[Rifampin results in increased activity of NR1I2 protein] which results in increased activity of CYP3A4 protein] which results in increased metabolism of and results in increased activity of and results in increased susceptibility to Cobicistat |
CTD |
PMID:33629115 |
|
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
|
|
G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
multiple interactions |
ISO |
[1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased activity of NR1I3 protein] which results in increased susceptibility to Cobicistat |
CTD |
PMID:33629115 |
|
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
|
|
|
G |
Braf |
B-Raf proto-oncogene, serine/threonine kinase |
multiple interactions affects response to substance increases response to substance decreases activity |
ISO |
[BRAF protein affects the susceptibility to dabrafenib] which affects the cleavage of SREBF1 protein; betulin affects the reaction [BRAF protein affects the susceptibility to [dabrafenib co-treated with trametinib]]; BRAF protein affects the susceptibility to [dabrafenib co-treated with trametinib]; CCND1 protein inhibits the reaction [BRAF protein mutant form results in increased susceptibility to dabrafenib]; fatostatin affects the reaction [BRAF protein affects the susceptibility to [dabrafenib co-treated with trametinib]]; MAPK1 protein modified form inhibits the reaction [BRAF protein mutant form results in increased susceptibility to dabrafenib]; MAPK3 protein modified form inhibits the reaction [BRAF protein mutant form results in increased susceptibility to dabrafenib] dabrafenib results in decreased activity of BRAF protein; dabrafenib results in decreased activity of BRAF protein mutant form |
CTD |
PMID:20823850 PMID:23237741 PMID:26978007 PMID:29950559 |
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NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
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G |
Ccnd1 |
cyclin D1 |
multiple interactions |
ISO |
CCND1 protein inhibits the reaction [BRAF protein mutant form results in increased susceptibility to dabrafenib] |
CTD |
PMID:26978007 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
ISO |
dabrafenib inhibits the reaction [Polyphosphates results in increased expression of GPT protein] |
CTD |
PMID:27458080 |
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NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
dabrafenib inhibits the reaction [Polyphosphates results in increased expression of ICAM1 mRNA]; dabrafenib inhibits the reaction [Polyphosphates results in increased expression of ICAM1 protein]; dabrafenib inhibits the reaction [TGFBI protein results in increased expression of ICAM1 protein] |
CTD |
PMID:27458080 PMID:29042256 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
dabrafenib inhibits the reaction [Polyphosphates results in increased secretion of IL6 protein] |
CTD |
PMID:27458080 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Itgav |
integrin subunit alpha V |
multiple interactions |
ISO |
dabrafenib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of [ITGAV protein binds to ITGB5 protein]] |
CTD |
PMID:29042256 |
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NCBI chr 3:68,838,524...68,926,653
Ensembl chr 3:68,838,189...68,926,639
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G |
Itgb5 |
integrin subunit beta 5 |
multiple interactions |
ISO |
dabrafenib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of [ITGAV protein binds to ITGB5 protein]] |
CTD |
PMID:29042256 |
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NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
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G |
Kras |
KRAS proto-oncogene, GTPase |
affects response to substance multiple interactions |
ISO |
KRAS protein affects the susceptibility to dabrafenib [KRAS protein affects the susceptibility to dabrafenib] which affects the expression of TNFRSF10B protein; [KRAS protein affects the susceptibility to dabrafenib] which affects the phosphorylation of MAPK1 protein; [KRAS protein affects the susceptibility to dabrafenib] which affects the phosphorylation of MAPK3 protein |
CTD |
PMID:27222248 |
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NCBI chr 4:178,185,418...178,218,484
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO |
[KRAS protein affects the susceptibility to dabrafenib] which affects the phosphorylation of MAPK1 protein; dabrafenib inhibits the reaction [Polyphosphates results in increased phosphorylation of MAPK1 protein]; MAPK1 protein modified form inhibits the reaction [BRAF protein mutant form results in increased susceptibility to dabrafenib]; SRPIN340 inhibits the reaction [dabrafenib results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:26978007 PMID:27222248 PMID:27458080 PMID:31962201 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO |
[KRAS protein affects the susceptibility to dabrafenib] which affects the phosphorylation of MAPK3 protein; dabrafenib inhibits the reaction [Polyphosphates results in increased phosphorylation of MAPK3 protein]; MAPK3 protein modified form inhibits the reaction [BRAF protein mutant form results in increased susceptibility to dabrafenib]; SRPIN340 inhibits the reaction [dabrafenib results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:26978007 PMID:27222248 PMID:27458080 PMID:31962201 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
dabrafenib inhibits the reaction [Polyphosphates results in increased activity of RELA protein] |
CTD |
PMID:27458080 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Sele |
selectin E |
multiple interactions |
ISO |
dabrafenib inhibits the reaction [Polyphosphates results in increased expression of SELE mRNA]; dabrafenib inhibits the reaction [Polyphosphates results in increased expression of SELE protein]; dabrafenib inhibits the reaction [TGFBI protein results in increased expression of SELE protein] |
CTD |
PMID:27458080 PMID:29042256 |
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NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
decreases cleavage multiple interactions |
ISO |
dabrafenib results in decreased cleavage of SREBF1 protein [BRAF protein affects the susceptibility to dabrafenib] which affects the cleavage of SREBF1 protein |
CTD |
PMID:29950559 |
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NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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G |
Srsf5 |
serine and arginine rich splicing factor 5 |
multiple interactions |
ISO |
[SRPIN340 co-treated with dabrafenib] results in decreased phosphorylation of SRSF5 protein |
CTD |
PMID:31962201 |
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NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177
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G |
Tgfbi |
transforming growth factor, beta induced |
multiple interactions |
ISO |
dabrafenib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TGFBI mRNA]; dabrafenib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TGFBI protein]; dabrafenib inhibits the reaction [TGFBI protein results in increased expression of ICAM1 protein]; dabrafenib inhibits the reaction [TGFBI protein results in increased expression of SELE protein]; dabrafenib inhibits the reaction [TGFBI protein results in increased expression of VCAM1 protein] |
CTD |
PMID:29042256 |
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NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
dabrafenib inhibits the reaction [Polyphosphates results in increased expression of TNF protein] |
CTD |
PMID:27458080 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
ISO |
dabrafenib inhibits the reaction [Polyphosphates results in increased expression of VCAM1 mRNA]; dabrafenib inhibits the reaction [Polyphosphates results in increased expression of VCAM1 protein]; dabrafenib inhibits the reaction [TGFBI protein results in increased expression of VCAM1 protein] |
CTD |
PMID:27458080 PMID:29042256 |
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NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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G |
Casp3 |
caspase 3 |
increases expression multiple interactions |
ISO |
epothilone A results in increased expression of CASP3 mRNA [epothilone A co-treated with Metformin] results in increased expression of CASP3 mRNA; Sodium Salicylate promotes the reaction [[epothilone A co-treated with Metformin] results in increased expression of CASP3 mRNA]; triciribine promotes the reaction [[epothilone A co-treated with Metformin] results in increased expression of CASP3 mRNA] |
CTD |
PMID:29117515 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
H2ax |
H2A.X variant histone |
multiple interactions increases expression |
ISO |
[epothilone A co-treated with Metformin] results in increased expression of H2AX mRNA epothilone A results in increased expression of H2AX mRNA |
CTD |
PMID:29117515 |
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NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions increases expression |
ISO |
[epothilone A co-treated with Metformin] results in increased expression of PARP1 mRNA; Sodium Salicylate inhibits the reaction [epothilone A results in increased expression of PARP1 mRNA]; triciribine inhibits the reaction [epothilone A results in increased expression of PARP1 mRNA]; triciribine promotes the reaction [[epothilone A co-treated with Metformin] results in increased expression of PARP1 mRNA] |
CTD |
PMID:29117515 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Calca |
calcitonin-related polypeptide alpha |
decreases expression multiple interactions |
EXP |
epothilone B results in decreased expression of CALCA protein epothilone B affects the reaction [[Capsaicin co-treated with NGF protein] results in increased secretion of CALCA protein]; epothilone B inhibits the reaction [Potassium results in increased secretion of CALCA protein]; epothilone B promotes the reaction [[Potassium co-treated with NGF protein] results in increased secretion of CALCA protein] |
CTD |
PMID:26883566 |
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NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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G |
Ngf |
nerve growth factor |
multiple interactions |
EXP |
epothilone B affects the reaction [[Capsaicin co-treated with NGF protein] results in increased secretion of CALCA protein]; epothilone B promotes the reaction [[Potassium co-treated with NGF protein] results in increased secretion of CALCA protein] |
CTD |
PMID:26883566 |
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NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
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G |
Adcyap1 |
adenylate cyclase activating polypeptide 1 |
multiple interactions |
ISO |
Famotidine inhibits the reaction [ADCYAP1 protein affects the secretion of Acids] |
CTD |
PMID:20388963 |
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NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
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G |
Agt |
angiotensinogen |
multiple interactions |
EXP |
Famotidine inhibits the reaction [Indomethacin results in increased expression of AGT protein] |
CTD |
PMID:27645307 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Braf |
B-Raf proto-oncogene, serine/threonine kinase |
decreases activity |
ISO |
Famotidine results in decreased activity of BRAF protein |
CTD |
PMID:20823850 |
|
NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
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G |
Car12 |
carbonic anhydrase 12 |
multiple interactions |
ISO |
Famotidine binds to and results in decreased activity of CA12 protein |
CTD |
PMID:30344913 |
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NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440
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G |
Car2 |
carbonic anhydrase 2 |
multiple interactions |
ISO |
Famotidine binds to and results in decreased activity of CA2 protein |
CTD |
PMID:30344913 |
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NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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G |
Car6 |
carbonic anhydrase 6 |
multiple interactions |
ISO |
Famotidine binds to and results in decreased activity of CA6 protein |
CTD |
PMID:30344913 |
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NCBI chr 5:160,658,104...160,676,644
Ensembl chr 5:160,658,105...160,676,644
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G |
Car7 |
carbonic anhydrase 7 |
multiple interactions |
ISO |
Famotidine binds to and results in decreased activity of CA7 protein |
CTD |
PMID:30344913 |
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NCBI chr19:429,063...438,478
Ensembl chr19:429,075...438,467
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G |
Cat |
catalase |
multiple interactions |
EXP |
Famotidine inhibits the reaction [Indomethacin results in decreased activity of CAT protein]; Famotidine inhibits the reaction [Indomethacin results in increased activity of CAT protein]; Quercetin promotes the reaction [Famotidine inhibits the reaction [Indomethacin results in decreased activity of CAT protein]] |
CTD |
PMID:18726076 PMID:19034656 PMID:19497431 PMID:25926722 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cd80 |
Cd80 molecule |
multiple interactions |
ISO |
Famotidine inhibits the reaction [Histamine inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein]] |
CTD |
PMID:12538815 |
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NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions increases expression |
ISO |
Famotidine inhibits the reaction [Dizocilpine Maleate results in decreased expression of CTNNB1 mRNA] Famotidine results in increased expression of CTNNB1 mRNA |
CTD |
PMID:31563592 |
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NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
increases expression |
EXP |
Famotidine results in increased expression of CXCL1 protein |
CTD |
PMID:12023551 |
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NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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G |
Cyp2c6v1 |
cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 |
multiple interactions |
ISO |
Famotidine inhibits the reaction [CYP2C19 gene affects the susceptibility to Lansoprazole] |
CTD |
PMID:15963082 |
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NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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G |
Fgf2 |
fibroblast growth factor 2 |
multiple interactions |
ISO |
[Famotidine co-treated with Sucralfate] results in increased expression of FGF2 mRNA |
CTD |
PMID:17717918 |
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NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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G |
Fgf21 |
fibroblast growth factor 21 |
increases expression |
ISO |
Famotidine results in increased expression of FGF21 protein |
CTD |
PMID:8774986 |
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NCBI chr 1:96,083,495...96,084,738
Ensembl chr 1:96,083,441...96,090,454
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Famotidine inhibits the reaction [[Dimaprit binds to and results in increased activity of HRH2 protein] which results in increased expression of FOS mRNA]; Famotidine inhibits the reaction [[Histamine binds to and results in increased activity of HRH2 protein] which results in increased expression of FOS mRNA] |
CTD |
PMID:9187264 |
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Gabra1 |
gamma-aminobutyric acid type A receptor subunit alpha 1 |
multiple interactions |
EXP |
Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein]] |
CTD |
PMID:15363660 |
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NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
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G |
Gabra3 |
gamma-aminobutyric acid type A receptor subunit alpha 3 |
multiple interactions |
EXP |
Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG2 protein]] |
CTD |
PMID:15363660 |
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NCBI chr X:150,244,745...150,501,566
Ensembl chr X:150,261,607...150,501,559
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G |
Gabrb2 |
gamma-aminobutyric acid type A receptor subunit beta 2 |
multiple interactions |
EXP |
Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG2 protein]] |
CTD |
PMID:15363660 |
|
NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
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G |
Gabrg1 |
gamma-aminobutyric acid type A receptor subunit gamma 1 |
multiple interactions |
EXP |
Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG1 protein]] |
CTD |
PMID:15363660 |
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NCBI chr14:37,396,217...37,469,606
Ensembl chr14:37,396,294...37,635,956
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G |
Gabrg2 |
gamma-aminobutyric acid type A receptor subunit gamma 2 |
multiple interactions |
EXP |
Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG2 protein]] |
CTD |
PMID:15363660 |
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NCBI chr10:26,376,805...26,463,680
Ensembl chr10:26,374,694...26,464,346
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G |
Gast |
gastrin |
affects expression increases expression |
ISO EXP |
Famotidine affects the expression of GAST protein Famotidine results in increased expression of GAST protein |
CTD |
PMID:12503773 PMID:17652263 |
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NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496
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G |
Ghrl |
ghrelin and obestatin prepropeptide |
multiple interactions |
EXP |
Famotidine inhibits the reaction [GHRL protein results in increased secretion of Acids] |
CTD |
PMID:16838121 |
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NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions |
ISO |
Famotidine inhibits the reaction [Dizocilpine Maleate results in decreased phosphorylation of and results in increased activity of GSK3B protein]; Famotidine inhibits the reaction [Dizocilpine Maleate results in increased expression of GSK3B mRNA] |
CTD |
PMID:31563592 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Hrh2 |
histamine receptor H 2 |
multiple interactions decreases activity increases expression |
ISO EXP |
[Famotidine binds to and results in decreased activity of HRH2 protein] which affects the susceptibility to Metformin; Famotidine binds to and results in decreased activity of HRH2 protein; Famotidine inhibits the reaction [[Dimaprit binds to and results in increased activity of HRH2 protein] which results in increased expression of FOS mRNA]; Famotidine inhibits the reaction [[Histamine binds to and results in increased activity of HRH2 protein] which results in increased expression of FOS mRNA] Famotidine results in decreased activity of HRH2 protein [Famotidine binds to and results in decreased activity of HRH2 protein] which affects the susceptibility to Histamine Famotidine results in increased expression of HRH2 protein |
CTD |
PMID:9187264 PMID:9681472 PMID:12832840 PMID:15961859 PMID:16632449 PMID:21276809 More...
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NCBI chr17:10,368,355...10,407,791
Ensembl chr17:10,368,298...10,407,631
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G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
decreases expression multiple interactions |
EXP |
Famotidine results in decreased expression of HSPA1A protein Zinc Compounds analog inhibits the reaction [Famotidine results in decreased expression of HSPA1A protein]; Zinc Sulfate inhibits the reaction [Famotidine results in decreased expression of HSPA1A protein] |
CTD |
PMID:16945336 |
|
|
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of ICAM1 protein]]; Famotidine inhibits the reaction [Histamine inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]] |
CTD |
PMID:11752121 PMID:12364868 PMID:12538815 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of IFNG protein]] Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]] |
CTD |
PMID:11752121 PMID:12364868 PMID:19277450 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Il10 |
interleukin 10 |
multiple interactions |
ISO |
Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in decreased expression of IL10 protein]] |
CTD |
PMID:11752121 |
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il12a |
interleukin 12A |
multiple interactions |
ISO |
Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]] |
CTD |
PMID:11752121 PMID:12364868 |
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NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
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G |
Il12b |
interleukin 12B |
multiple interactions |
ISO |
Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]] |
CTD |
PMID:11752121 PMID:12364868 |
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NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
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G |
Il18 |
interleukin 18 |
multiple interactions |
ISO |
Famotidine inhibits the reaction [Cimetidine results in increased expression of IL18 protein]; Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in decreased expression of IL10 protein]]; Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]]; Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of ICAM1 protein]]; Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of IFNG protein]]; Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of TNF protein]] |
CTD |
PMID:11752121 PMID:12364868 PMID:16723495 |
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NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO EXP |
[Famotidine co-treated with Sucralfate] results in decreased expression of IL1B mRNA Famotidine inhibits the reaction [Ethanol results in increased expression of IL1B protein]; Famotidine inhibits the reaction [Indomethacin results in increased expression of IL1B mRNA] |
CTD |
PMID:17717918 PMID:27474069 PMID:27645307 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il2 |
interleukin 2 |
multiple interactions |
ISO |
Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]] |
CTD |
PMID:19277450 |
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il4 |
interleukin 4 |
multiple interactions |
ISO |
Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]] |
CTD |
PMID:19277450 |
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il6 |
interleukin 6 |
multiple interactions |
EXP |
Famotidine inhibits the reaction [Ethanol results in increased expression of IL6 protein]; Famotidine inhibits the reaction [Ethanol results in increased secretion of IL6 protein] |
CTD |
PMID:17603938 PMID:27474069 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
Famotidine inhibits the reaction [Histamine results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:17656145 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
Famotidine inhibits the reaction [Histamine results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:17656145 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mmp1 |
matrix metallopeptidase 1 |
multiple interactions |
ISO |
Famotidine inhibits the reaction [Histamine results in increased expression of MMP1 mRNA]; Famotidine inhibits the reaction [Histamine results in increased secretion of MMP1 protein] |
CTD |
PMID:17656145 |
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NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions |
EXP |
Famotidine inhibits the reaction [Ethanol results in increased expression of and results in increased activity of MMP9 protein]; Famotidine inhibits the reaction [Ethanol results in increased expression of MMP9 mRNA]; Famotidine inhibits the reaction [Ethanol results in increased secretion of and results in increased activity of MMP9 protein]; Famotidine inhibits the reaction [Ethanol results in increased secretion of MMP9 protein] |
CTD |
PMID:17603938 PMID:22257724 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mpo |
myeloperoxidase |
multiple interactions increases expression |
ISO EXP |
Famotidine inhibits the reaction [Acids results in increased activity of MPO protein] Famotidine results in increased expression of MPO protein Famotidine inhibits the reaction [Ethanol results in increased activity of MPO protein]; Famotidine inhibits the reaction [Indomethacin results in increased activity of MPO protein]; Famotidine promotes the reaction [Chlorpheniramine results in decreased activity of MPO protein]; Quercetin promotes the reaction [Famotidine inhibits the reaction [Indomethacin results in increased activity of MPO protein]] |
CTD |
PMID:12023551 PMID:16091555 PMID:16437673 PMID:17603938 PMID:18726076 PMID:19034656 PMID:19497431 PMID:20723003 PMID:22257724 PMID:25926722 PMID:27474069 More...
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NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Nppb |
natriuretic peptide B |
decreases expression |
EXP |
Famotidine results in decreased expression of NPPB protein |
CTD |
PMID:30310171 |
|
NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
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G |
Ntf3 |
neurotrophin 3 |
multiple interactions |
EXP |
[Pyrilamine co-treated with Famotidine co-treated with ciproxifan] inhibits the reaction [Histamine results in increased expression of NTF3 protein]; [Pyrilamine co-treated with Famotidine] inhibits the reaction [Histamine results in increased expression of NTF3 protein]; Famotidine inhibits the reaction [Histamine results in increased expression of NTF3 protein] |
CTD |
PMID:21276809 |
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NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596
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G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions |
EXP |
[Famotidine co-treated with Indomethacin] promotes the reaction [Acetic Acid results in increased expression of PCNA protein]; Famotidine promotes the reaction [Acetic Acid results in increased expression of PCNA protein] |
CTD |
PMID:18853145 PMID:19251492 |
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NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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G |
Ppp3ca |
protein phosphatase 3 catalytic subunit alpha |
decreases expression |
EXP |
Famotidine results in decreased expression of PPP3CA protein |
CTD |
PMID:30310171 |
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NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
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G |
Prdx3 |
peroxiredoxin 3 |
increases expression |
EXP |
Famotidine results in increased expression of PRDX3 protein |
CTD |
PMID:30310171 |
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NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
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G |
Prl |
prolactin |
increases expression |
ISO |
Famotidine results in increased expression of PRL protein |
CTD |
PMID:8104296 |
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NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
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G |
Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
multiple interactions |
EXP |
Famotidine inhibits the reaction [Indomethacin results in increased expression of PTGS1 mRNA] |
CTD |
PMID:27645307 |
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NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
EXP |
Famotidine inhibits the reaction [Indomethacin results in increased expression of PTGS2 mRNA] |
CTD |
PMID:27645307 |
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NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
EXP |
Famotidine inhibits the reaction [Ethanol results in increased expression of RELA protein] |
CTD |
PMID:27474069 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
RT1-A2 |
RT1 class Ia, locus A2 |
affects expression |
ISO |
Famotidine affects the expression of HLA-E mRNA |
CTD |
PMID:25811541 |
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NCBI chr20:4,870,939...4,910,183
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G |
RT1-DMb |
RT1 class II, locus DMb |
affects expression |
ISO |
Famotidine affects the expression of HLA-DMB mRNA |
CTD |
PMID:25811541 |
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NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340
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G |
Serpine1 |
serpin family E member 1 |
multiple interactions |
EXP |
Heparin promotes the reaction [[Famotidine co-treated with Lipopolysaccharides] results in increased expression of SERPINE1 protein] |
CTD |
PMID:16401727 |
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NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Slc19a3 |
solute carrier family 19 member 3 |
multiple interactions increases uptake |
ISO |
Famotidine inhibits the reaction [SLC19A3 protein results in increased uptake of Metformin]; Famotidine inhibits the reaction [SLC19A3 protein results in increased uptake of Thiamine] SLC19A3 protein results in increased uptake of Famotidine |
CTD |
PMID:26528626 |
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NCBI chr 9:84,275,722...84,299,368
Ensembl chr 9:84,277,024...84,299,337
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G |
Slc22a1 |
solute carrier family 22 member 1 |
multiple interactions increases uptake affects transport |
ISO EXP |
Famotidine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] SLC22A1 protein results in increased uptake of Famotidine SLC22A1 protein affects the transport of Famotidine |
CTD |
PMID:16006492 PMID:16141367 |
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NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
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G |
Slc22a2 |
solute carrier family 22 member 2 |
increases uptake multiple interactions |
ISO EXP |
SLC22A2 protein results in increased uptake of Famotidine Famotidine inhibits the reaction [SLC22A2 protein affects the transport of Tetraethylammonium]; Famotidine inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]; Famotidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] |
CTD |
PMID:15496291 PMID:16006492 PMID:16141367 PMID:21599003 |
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NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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G |
Slc22a3 |
solute carrier family 22 member 3 |
multiple interactions decreases activity |
ISO |
Famotidine inhibits the reaction [SLC22A3 protein affects the transport of 1-Methyl-4-phenylpyridinium]; Famotidine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] Famotidine results in decreased activity of SLC22A3 protein |
CTD |
PMID:16141367 |
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NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
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G |
Slc22a8 |
solute carrier family 22 member 8 |
multiple interactions increases uptake |
ISO EXP |
estrone sulfate inhibits the reaction [SLC22A8 protein results in increased uptake of Famotidine]; Famotidine inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate]; Probenecid inhibits the reaction [SLC22A8 protein affects the transport of Famotidine] Famotidine inhibits the reaction [SLC22A8 protein results in increased uptake of Cimetidine]; Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of Famotidine]; Probenecid inhibits the reaction [SLC22A8 protein affects the transport of Famotidine]; Probenecid promotes the reaction [SLC22A8 protein results in increased uptake of Famotidine] Famotidine inhibits the reaction [SLC22A8 protein results in increased uptake of p-Aminohippuric Acid] |
CTD |
PMID:15100168 PMID:15319347 PMID:15496291 PMID:16006492 |
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NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
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G |
Slc47a1 |
solute carrier family 47 member 1 |
multiple interactions |
ISO |
Famotidine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] |
CTD |
PMID:22419765 |
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NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637
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G |
Slc47a2 |
solute carrier family 47 member 2 |
multiple interactions |
ISO |
Famotidine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] |
CTD |
PMID:22419765 |
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NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904
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G |
Tacr1 |
tachykinin receptor 1 |
multiple interactions |
ISO |
Famotidine inhibits the reaction [Acids affects the localization of TACR1 protein] |
CTD |
PMID:16091555 |
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NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733
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G |
Tnf |
tumor necrosis factor |
multiple interactions increases secretion |
ISO EXP |
Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of TNF protein]]; Famotidine inhibits the reaction [Histamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]] Famotidine results in increased secretion of TNF protein Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]] Famotidine inhibits the reaction [Ethanol results in increased expression of TNF protein]; Famotidine inhibits the reaction [Ethanol results in increased secretion of TNF protein]; Famotidine inhibits the reaction [Indomethacin results in increased expression of TNF mRNA] |
CTD |
PMID:11752121 PMID:12538815 PMID:17603938 PMID:17698507 PMID:19277450 PMID:27474069 PMID:27645307 More...
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Ager |
advanced glycosylation end product-specific receptor |
multiple interactions |
EXP |
Febuxostat inhibits the reaction [Paraquat results in decreased secretion of AGER protein modified form]; Febuxostat inhibits the reaction [Paraquat results in increased expression of AGER mRNA] |
CTD |
PMID:30726711 |
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NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
EXP |
Febuxostat inhibits the reaction [Doxorubicin results in increased expression of BAX protein] |
CTD |
PMID:26036690 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
EXP |
Febuxostat inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein] |
CTD |
PMID:26036690 |
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NCBI chr13:22,689,783...22,853,920
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G |
Casp3 |
caspase 3 |
multiple interactions |
EXP |
Febuxostat inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein] |
CTD |
PMID:26036690 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression |
ISO |
Febuxostat results in increased expression of CCL2 mRNA |
CTD |
PMID:26641773 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions |
EXP |
Febuxostat inhibits the reaction [Paraquat results in increased expression of CTNNB1 protein] |
CTD |
PMID:30726711 |
|
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Got2 |
glutamic-oxaloacetic transaminase 2 |
multiple interactions |
ISO |
Febuxostat inhibits the reaction [[myelin oligodendrocyte glycoprotein (35-55) co-treated with Freund's Adjuvant] results in decreased expression of GOT2 mRNA]; Febuxostat inhibits the reaction [[myelin oligodendrocyte glycoprotein (35-55) co-treated with Freund's Adjuvant] results in decreased expression of GOT2 protein] |
CTD |
PMID:29107957 |
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NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
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G |
Hmgb1 |
high mobility group box 1 |
multiple interactions |
EXP |
Febuxostat inhibits the reaction [Paraquat results in increased expression of HMGB1 mRNA] |
CTD |
PMID:30726711 |
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NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions |
EXP |
Febuxostat inhibits the reaction [Doxorubicin results in increased expression of IKBKB protein] |
CTD |
PMID:26036690 |
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NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions |
EXP |
Febuxostat inhibits the reaction [Paraquat results in increased expression of MMP9 protein] |
CTD |
PMID:30726711 |
|
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Nppb |
natriuretic peptide B |
multiple interactions |
EXP |
Febuxostat inhibits the reaction [Doxorubicin results in increased expression of NPPB protein] |
CTD |
PMID:26036690 |
|
NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
EXP |
Febuxostat inhibits the reaction [Paraquat results in increased expression of PTGS2 mRNA] |
CTD |
PMID:30726711 |
|
NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
EXP |
Febuxostat inhibits the reaction [Doxorubicin results in increased expression of RELA protein] |
CTD |
PMID:26036690 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions |
EXP |
Febuxostat inhibits the reaction [Doxorubicin results in decreased expression of SOD2 protein] |
CTD |
PMID:26036690 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Tnf |
tumor necrosis factor |
multiple interactions increases expression |
EXP ISO |
Febuxostat inhibits the reaction [Doxorubicin results in increased expression of TNF protein] Febuxostat results in increased expression of TNF mRNA |
CTD |
PMID:26036690 PMID:26641773 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
EXP |
Febuxostat inhibits the reaction [Paraquat results in increased expression of VEGFA protein] |
CTD |
PMID:30726711 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Cyp2f4 |
cytochrome P450, family 2, subfamily f, polypeptide 4 |
increases response to substance increases metabolic processing |
ISO |
CYP2F2 protein results in increased susceptibility to fluensulfone CYP2F2 protein results in increased metabolism of fluensulfone |
CTD |
PMID:27605420 |
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NCBI chr 1:82,416,108...82,429,897
Ensembl chr 1:82,416,130...82,429,896
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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
increases expression |
ISO |
GW 501516 results in increased expression of ABCA1 mRNA; GW 501516 results in increased expression of ABCA1 protein |
CTD |
PMID:19201410 |
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NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Abhd3 |
abhydrolase domain containing 3, phospholipase |
multiple interactions |
ISO |
[GW 501516 binds to PPARD protein] which results in increased expression of ABHD3 mRNA |
CTD |
PMID:16197558 |
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NCBI chr18:1,723,203...1,778,488
Ensembl chr18:1,720,718...1,803,428
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G |
Acadm |
acyl-CoA dehydrogenase medium chain |
multiple interactions |
ISO |
[GW 501516 binds to PPARD protein] which results in increased expression of ACADM mRNA |
CTD |
PMID:16197558 |
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NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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G |
Acadvl |
acyl-CoA dehydrogenase, very long chain |
multiple interactions |
ISO |
[GW 501516 binds to PPARD protein] which results in increased expression of ACADVL mRNA |
CTD |
PMID:16197558 |
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NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
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G |
Acox1 |
acyl-CoA oxidase 1 |
increases expression |
ISO |
GW 501516 results in increased expression of ACOX1 mRNA |
CTD |
PMID:16574099 |
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NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
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G |
Angptl4 |
angiopoietin-like 4 |
multiple interactions increases expression |
ISO |
[GW 501516 binds to PPARD protein] which results in increased expression of ANGPTL4 mRNA GW 501516 results in increased expression of ANGPTL4 mRNA |
CTD |
PMID:16197558 PMID:34627044 |
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NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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G |
Apoa1 |
apolipoprotein A1 |
multiple interactions |
ISO |
GW 501516 promotes the reaction [APOA1 protein results in increased secretion of Lipids] |
CTD |
PMID:19201410 |
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NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
GW 501516 inhibits the reaction [APP gene mutant f | |