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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:thiazoles
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Accession:CHEBI:48901 term browser browse the term
Definition:An azole in which the five-membered heterocyclic aromatic skeleton contains a N atom and one S atom.
Synonyms:related_synonym: thiazole
 alt_id: MESH:D013844
 xref_mesh: MESH:D013844

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thiazoles term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bid BH3 interacting domain death agonist multiple interactions ISO [Heterocyclic Compounds binds to Thiazoles] which results in decreased expression of BID protein CTD PMID:19014919 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Heterocyclic Compounds binds to Thiazoles] which results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [[Heterocyclic Compounds binds to Thiazoles] which results in increased activity of CASP3 protein] CTD PMID:19014919 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO [Heterocyclic Compounds binds to Thiazoles] which results in increased activity of CASP8 protein; Acetylcysteine inhibits the reaction [[Heterocyclic Compounds binds to Thiazoles] which results in increased activity of CASP8 protein] CTD PMID:19014919 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106 		JBrowse link
G Cat catalase multiple interactions ISO CAT inhibits the reaction [[Heterocyclic Compounds binds to Thiazoles] which results in increased abundance of Reactive Oxygen Species] CTD PMID:19014919 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP [Thiazoles co-treated with ciprofibrate] results in increased expression of CYP2E1 protein CTD PMID:7587954 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP Thiazoles results in increased expression of EPHX1 mRNA CTD PMID:8951341 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO [Heterocyclic Compounds binds to Thiazoles] which results in increased expression of FAS protein; Acetylcysteine inhibits the reaction [[Heterocyclic Compounds binds to Thiazoles] which results in increased expression of FAS protein] CTD PMID:19014919 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP Thiazoles results in increased expression of GSTA2 mRNA; Thiazoles results in increased expression of GSTA2 protein; Thiazoles results in increased expression of GSTA3 mRNA; Thiazoles results in increased expression of GSTA3 protein CTD PMID:8951341 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP Thiazoles results in increased expression of GSTA5 mRNA CTD PMID:8951341 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP Thiazoles results in increased expression of GSTM1 mRNA; Thiazoles results in increased expression of GSTM1 protein CTD PMID:8951341 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression EXP Thiazoles results in increased expression of GSTM2 mRNA; Thiazoles results in increased expression of GSTM2 protein CTD PMID:8951341 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856 		JBrowse link
G Il5 interleukin 5 multiple interactions ISO Dithiothreitol inhibits the reaction [Thiazoles analog inhibits the reaction [IL5 protein binds to IL5RA protein]]; Thiazoles analog inhibits the reaction [IL5 protein binds to IL5RA protein] CTD PMID:7957178 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587 		JBrowse link
G Il5ra interleukin 5 receptor subunit alpha multiple interactions ISO Dithiothreitol inhibits the reaction [Thiazoles analog inhibits the reaction [IL5 protein binds to IL5RA protein]]; Thiazoles analog inhibits the reaction [IL5 protein binds to IL5RA protein] CTD PMID:7957178 NCBI chr 4:138,796,165...138,834,164
Ensembl chr 4:138,795,327...138,830,117 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP [Thiazoles analog binds to indoline analog] inhibits the reaction [SESN2 protein promotes the reaction [Hydrogen Peroxide results in increased activity of NFE2L2 protein]]; [Thiazoles analog binds to indoline analog] which results in decreased activity of NFE2L2 protein CTD PMID:32275923 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Rarg retinoic acid receptor, gamma multiple interactions ISO Thiazoles binds to and results in increased activity of RARG protein CTD PMID:17076708 NCBI chr 7:143,840,739...143,863,206
Ensembl chr 7:143,839,980...143,863,186 		JBrowse link
G Sesn2 sestrin 2 multiple interactions EXP [Thiazoles analog binds to indoline analog] inhibits the reaction [SESN2 protein promotes the reaction [Hydrogen Peroxide results in increased activity of NFE2L2 protein]] CTD PMID:32275923 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117 		JBrowse link
G Slc1a5 solute carrier family 1 member 5 multiple interactions
decreases activity		 EXP Dithioerythritol inhibits the reaction [Thiazoles analog results in decreased activity of SLC1A5 protein] CTD PMID:23010140 NCBI chr 1:78,710,686...78,724,789
Ensembl chr 1:78,710,539...78,724,794 		JBrowse link
(E)-thiamethoxam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa10 annexin A10 increases expression ISO Thiamethoxam results in increased expression of ANXA10 mRNA CTD PMID:32194361 NCBI chr16:29,674,699...29,741,521
Ensembl chr16:29,674,793...29,741,465 		JBrowse link
G Ar androgen receptor affects binding ISO Thiamethoxam binds to AR protein CTD PMID:31550567 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
G Arg1 arginase 1 decreases expression ISO Thiamethoxam results in decreased expression of ARG1 mRNA CTD PMID:32194361 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP Thiamethoxam results in increased activity of [NACHRA1 protein co-treated with CHRNB2 protein] CTD PMID:16981889 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression
increases activity		 ISO Thiamethoxam results in increased expression of CYP19A1 mRNA
Thiamethoxam results in increased activity of CYP19A1 protein		 CTD PMID:26464060, PMID:28750898 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408 		JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases expression ISO Thiamethoxam results in decreased expression of CYP2C19 protein CTD PMID:32194361 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO Thiamethoxam results in decreased expression of CYP7A1 protein CTD PMID:32194361 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431 		JBrowse link
G Esr1 estrogen receptor 1 affects binding ISO Thiamethoxam binds to ESR1 protein CTD PMID:31550567 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO Thiamethoxam results in decreased expression of G6PC mRNA CTD PMID:32194361 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213 		JBrowse link
G Gpt glutamic--pyruvic transaminase decreases activity EXP Thiamethoxam results in decreased activity of GPT protein CTD PMID:29197058 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931 		JBrowse link
G Nos2 nitric oxide synthase 2 decreases activity
multiple interactions		 ISO Thiamethoxam metabolite results in decreased activity of NOS2 protein
[Thiamethoxam metabolite results in decreased activity of NOS2 protein] which results in increased chemical synthesis of Formaldehyde		 CTD PMID:29197058 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases activity ISO Thiamethoxam results in decreased activity of SLC22A2 protein CTD PMID:31364238 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261 		JBrowse link
G Thra thyroid hormone receptor alpha affects binding ISO Thiamethoxam binds to THRA protein CTD PMID:31550567 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933 		JBrowse link
G Tnnt2 troponin T2, cardiac type increases secretion
multiple interactions		 EXP Thiamethoxam results in increased secretion of TNNT2 protein
fenugreek seed meal inhibits the reaction [Thiamethoxam results in increased secretion of TNNT2 protein]; Polysaccharides inhibits the reaction [Thiamethoxam results in increased secretion of TNNT2 protein]		 CTD PMID:30520268 NCBI chr13:52,662,974...52,680,992
Ensembl chr13:52,662,996...52,680,990 		JBrowse link
1-(4-methoxybenzyl)-3-(5-nitro-1,3-thiazol-2-yl)urea term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 multiple interactions ISO N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [deoxynivalenol results in decreased degradation of ATF3 protein] CTD PMID:19101521 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in increased expression of BAX protein] CTD PMID:20540935 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP		 [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in increased expression of CASP3 protein]
N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Colchicine results in increased activity of CASP3 protein]		 CTD PMID:20300959, PMID:20540935 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in increased expression of CASP9 protein] CTD PMID:20540935 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778 		JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CCNB1 protein] CTD PMID:20540935 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CCND1 protein] CTD PMID:20540935 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325 		JBrowse link
G Ccne1 cyclin E1 multiple interactions ISO [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CCNE1 protein] CTD PMID:20540935 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980 		JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CDK2 protein] CTD PMID:20540935 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions ISO [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CDK4 protein] CTD PMID:20540935 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Arsenic Trioxide results in decreased expression of CTNNB1 protein] CTD PMID:32305283 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 affects localization EXP N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea affects the localization of GRIA1 protein CTD PMID:20534517 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 affects localization EXP N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea affects the localization of GRIA2 protein CTD PMID:20534517 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
decreases activity		 ISO
EXP		 [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [Troglitazone results in decreased expression of CCNB1 protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [Troglitazone results in decreased expression of CCND1 protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [Troglitazone results in decreased expression of CCNE1 protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [Troglitazone results in decreased expression of CDK2 protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [Troglitazone results in decreased expression of CDK4 protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [Troglitazone results in increased expression of BAX protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [Troglitazone results in increased expression of CASP3 protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [Troglitazone results in increased expression of CASP9 protein]; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] which results in decreased susceptibility to Okadaic Acid; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] which results in decreased susceptibility to Proadifen; [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] which results in increased susceptibility to Troglitazone; N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of GSK3B protein]; N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein modified form]; N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein] CTD PMID:16202587, PMID:20540935, PMID:21715663, PMID:22683934, PMID:32305283 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268 		JBrowse link
G Mapt microtubule-associated protein tau multiple interactions ISO [N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein] CTD PMID:21715663 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions ISO N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Arsenic Trioxide results in decreased expression of MCL1 protein] CTD PMID:32305283 NCBI chr 2:197,786,212...197,788,992 JBrowse link
4,5-dichloro-2-n-octyl-3(2H)-isothiazolone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dio1 iodothyronine deiodinase 1 decreases activity ISO Kathon 930 results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520 		JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases activity ISO Kathon 930 results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723 		JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO Kathon 930 results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr 6:134,627,278...134,629,139
Ensembl chr 6:134,627,278...134,629,138 		JBrowse link
5-(2-chloroethyl)-4-methylthiazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO Chlormethiazole inhibits the reaction [Ethanol results in decreased phosphorylation of and results in decreased expression of ACACA protein] CTD PMID:24892905 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO Chlormethiazole inhibits the reaction [Ethanol results in decreased expression of ADIPOQ] CTD PMID:25162931 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO Chlormethiazole inhibits the reaction [Ethanol results in decreased phosphorylation of AKT1 protein] CTD PMID:24892905 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions EXP Chlormethiazole inhibits the reaction [Acetaminophen results in increased degradation of CDKN1A protein] CTD PMID:16330492 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression EXP Chlormethiazole results in decreased expression of CYP1A1 protein CTD PMID:10751552 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression EXP Chlormethiazole results in decreased expression of CYP1A2 mRNA CTD PMID:10751552 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 multiple interactions ISO Chlormethiazole inhibits the reaction [Ethanol results in increased activity of CYP2A5 protein] CTD PMID:22552773 NCBI chr 1:83,653,248...83,662,118
Ensembl chr 1:83,653,234...83,766,484 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases activity
decreases expression		 ISO
EXP		 Chlormethiazole inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA]; Chlormethiazole inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]; Chlormethiazole inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]
Chlormethiazole results in decreased activity of CYP2E1 protein
[Chlormethiazole results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone; Chlormethiazole inhibits the reaction [Docosahexaenoic Acids results in increased expression of CYP2E1 protein]
Chlormethiazole results in decreased expression of CYP2E1 protein
Chlormethiazole results in decreased expression of CYP2E1 mRNA; Chlormethiazole results in decreased expression of CYP2E1 protein
Chlormethiazole inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]; Chlormethiazole inhibits the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride]		 CTD PMID:7601153, PMID:10751552, PMID:16330492, PMID:16963249, PMID:21684301, PMID:22552773, PMID:24892905, PMID:26599973 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542 		JBrowse link
G Cyp2g1 cytochrome P450, family 2, subfamily g, polypeptide 1 decreases expression EXP Chlormethiazole results in decreased expression of CYP2G1 protein CTD PMID:10751552 NCBI chr 1:83,626,639...83,638,154
Ensembl chr 1:83,626,639...83,637,780 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions ISO Chlormethiazole promotes the reaction [Ethanol results in increased expression of DGAT2 protein] CTD PMID:24892905 NCBI chr 1:164,113,459...164,143,818
Ensembl chr 1:164,113,459...164,143,818 		JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO Chlormethiazole inhibits the reaction [Ethanol results in decreased expression of EP300 protein] CTD PMID:24892905 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296 		JBrowse link
G Fasn fatty acid synthase multiple interactions ISO Chlormethiazole inhibits the reaction [Ethanol results in decreased expression of FASN protein] CTD PMID:24892905 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO Chlormethiazole inhibits the reaction [Ethanol results in decreased phosphorylation of GSK3B protein] CTD PMID:24892905 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Chlormethiazole inhibits the reaction [Ethanol results in decreased phosphorylation of MAPK1 protein] CTD PMID:24892905 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Chlormethiazole inhibits the reaction [Ethanol results in decreased phosphorylation of MAPK3 protein] CTD PMID:24892905 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO Chlormethiazole inhibits the reaction [Ethanol results in decreased expression of PPARA mRNA]; Chlormethiazole inhibits the reaction [Ethanol results in decreased expression of PPARA protein]; Chlormethiazole inhibits the reaction [Ethanol results in increased expression of PPARA protein] CTD PMID:24892905, PMID:25162931 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO Chlormethiazole affects the reaction [Ethanol results in decreased expression of PPARGC1A mRNA]; Chlormethiazole inhibits the reaction [Ethanol results in decreased acetylation of PPARGC1A protein] CTD PMID:24892905 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009 		JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO Chlormethiazole affects the reaction [Ethanol affects the expression of RXRA mRNA] CTD PMID:24892905 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908 		JBrowse link
G Sirt1 sirtuin 1 decreases expression
multiple interactions		 ISO Chlormethiazole results in decreased expression of SIRT1 protein
Chlormethiazole inhibits the reaction [Ethanol results in decreased expression of SIRT1 protein]		 CTD PMID:24892905 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199 		JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO Chlormethiazole inhibits the reaction [Methamphetamine results in decreased activity of TH protein] CTD PMID:1381816 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Chlormethiazole inhibits the reaction [Ethanol results in increased expression of TNF protein] CTD PMID:24892905 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP Chlormethiazole inhibits the reaction [Acetaminophen results in increased degradation of TP53 protein] CTD PMID:16330492 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
benfotiamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions
increases expression		 ISO NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of GCLM mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of GCLM mRNA]
benphothiamine metabolite results in increased expression of GCLM mRNA; benphothiamine results in increased expression of GCLM mRNA		 CTD PMID:29860433 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
increases expression		 ISO NFE2L2 protein affects the reaction [benphothiamine results in increased expression of GSR mRNA] CTD PMID:29860433 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions		 ISO benphothiamine metabolite results in increased expression of HMOX1 mRNA; benphothiamine results in increased expression of HMOX1 mRNA
benphothiamine inhibits the reaction [MAPT protein results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of HMOX1 mRNA]		 CTD PMID:29860433 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [benphothiamine co-treated with MAPT protein] results in decreased expression of IL1B protein CTD PMID:29860433 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Mapt microtubule-associated protein tau decreases phosphorylation
multiple interactions		 ISO benphothiamine results in decreased phosphorylation of MAPT protein
[benphothiamine co-treated with MAPT protein] results in decreased expression of IL1B protein; [benphothiamine co-treated with MAPT protein] results in decreased expression of NOS2 protein; [benphothiamine co-treated with MAPT protein] results in decreased expression of PTGS2 protein; [benphothiamine co-treated with MAPT protein] results in decreased expression of RELA protein; [benphothiamine co-treated with MAPT protein] results in decreased expression of TNF protein; [benphothiamine co-treated with MAPT protein] results in increased expression of NQO1 mRNA; [benphothiamine co-treated with MAPT protein] results in increased expression of TXN mRNA; benphothiamine inhibits the reaction [MAPT protein results in decreased activity of TKT protein]; benphothiamine inhibits the reaction [MAPT protein results in decreased expression of NOS2 mRNA]; benphothiamine inhibits the reaction [MAPT protein results in decreased expression of PPARGC1A protein]; benphothiamine inhibits the reaction [MAPT protein results in decreased expression of SOD1 protein]; benphothiamine inhibits the reaction [MAPT protein results in increased expression of HMOX1 mRNA]		 CTD PMID:29860433 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of GCLM mRNA]; NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of GCLM mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of GSR mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of NQO1 mRNA] CTD PMID:29860433 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO [benphothiamine co-treated with MAPT protein] results in decreased expression of NOS2 protein; benphothiamine inhibits the reaction [MAPT protein results in decreased expression of NOS2 mRNA] CTD PMID:29860433 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions		 ISO benphothiamine metabolite results in increased expression of NQO1 mRNA; benphothiamine results in increased expression of NQO1 mRNA
[benphothiamine co-treated with MAPT protein] results in increased expression of NQO1 mRNA; NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [benphothiamine results in increased expression of NQO1 mRNA]		 CTD PMID:29860433 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO benphothiamine inhibits the reaction [MAPT protein results in decreased expression of PPARGC1A protein] CTD PMID:29860433 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [benphothiamine co-treated with MAPT protein] results in decreased expression of PTGS2 protein CTD PMID:29860433 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [benphothiamine co-treated with MAPT protein] results in decreased expression of RELA protein CTD PMID:29860433 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO benphothiamine inhibits the reaction [MAPT protein results in decreased expression of SOD1 protein] CTD PMID:29860433 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862 		JBrowse link
G Tkt transketolase multiple interactions EXP
ISO		 [benphothiamine co-treated with Streptozocin] results in increased activity of TKT protein
benphothiamine inhibits the reaction [MAPT protein results in decreased activity of TKT protein]		 CTD PMID:12592403, PMID:29860433 NCBI chr16:6,609,670...6,634,608
Ensembl chr16:6,609,668...6,634,595 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [benphothiamine co-treated with MAPT protein] results in decreased expression of TNF protein CTD PMID:29860433 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Txn1 thioredoxin 1 multiple interactions ISO [benphothiamine co-treated with MAPT protein] results in increased expression of TXN mRNA CTD PMID:29860433 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752 		JBrowse link
camalexin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO camalexin metabolite results in increased expression of BAX mRNA CTD PMID:23339777 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO camalexin metabolite results in decreased expression of BCL2 mRNA CTD PMID:23339777 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO camalexin metabolite results in decreased expression of BCL2L1 mRNA CTD PMID:23339777 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810 		JBrowse link
cefoselis sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO cefoselis inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:16098483 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases uptake
multiple interactions		 ISO SLC22A8 protein results in increased uptake of cefoselis
cefoselis inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]		 CTD PMID:16098483 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482 		JBrowse link
cefotaxime term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Cefotaxime results in increased expression of BAX protein CTD PMID:15012731 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO Cefotaxime inhibits the reaction [Lipopolysaccharides results in increased secretion of IL10 protein] CTD PMID:16939481 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity EXP Cefotaxime results in decreased activity of PGD protein CTD PMID:15558954 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G RT1-CE5 RT1 class I, locus CE5 affects expression ISO Cefotaxime affects the expression of HLA-F mRNA CTD PMID:25811541 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO Cefotaxime results in increased expression of TP53 protein CTD PMID:15012731 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
ceftriaxone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin I converting enzyme 2 decreases expression EXP Ceftriaxone results in decreased expression of ACE2 mRNA CTD PMID:29745864 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016 		JBrowse link
G Actb actin, beta increases expression EXP Ceftriaxone results in increased expression of ACTB mRNA CTD PMID:29745864 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841 		JBrowse link
G Bace1 beta-secretase 1 decreases expression EXP Ceftriaxone results in decreased expression of BACE1 mRNA CTD PMID:29745864 NCBI chr 8:50,140,092...50,162,388
Ensembl chr 8:50,139,997...50,162,361 		JBrowse link
G Cat catalase decreases expression
multiple interactions		 ISO
EXP		 Ceftriaxone results in decreased expression of CAT protein
Ceftriaxone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased activity of CAT protein]; ropinirole promotes the reaction [Ceftriaxone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased activity of CAT protein]]		 CTD PMID:19442074, PMID:25053526 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Dhfr dihydrofolate reductase decreases activity ISO Ceftriaxone results in decreased activity of DHFR protein CTD PMID:25418905 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453 		JBrowse link
G Ece1 endothelin converting enzyme 1 increases expression EXP Ceftriaxone results in increased expression of ECE1 mRNA CTD PMID:29745864 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671 		JBrowse link
G Epo erythropoietin increases expression EXP Ceftriaxone results in increased expression of EPO mRNA CTD PMID:29745864 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266 		JBrowse link
G Ide insulin degrading enzyme increases expression EXP Ceftriaxone results in increased expression of IDE mRNA CTD PMID:29745864 NCBI chr 1:255,914,465...256,014,168
Ensembl chr 1:255,914,447...256,013,495 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Ceftriaxone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B protein]; ropinirole promotes the reaction [Ceftriaxone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B protein]] CTD PMID:25053526 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Mme membrane metallo-endopeptidase increases expression EXP Ceftriaxone results in increased expression of MME mRNA CTD PMID:29745864 NCBI chr 2:153,799,203...153,880,910
Ensembl chr 2:153,803,349...153,880,738 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 multiple interactions
increases expression		 EXP Ceftriaxone inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of SLC1A2 protein]; Ceftriaxone inhibits the reaction [Cocaine results in decreased expression of SLC1A2 protein]; Ceftriaxone promotes the reaction [Kainic Acid results in increased expression of SLC1A2 protein]
Ceftriaxone results in increased expression of SLC1A2 protein		 CTD PMID:19625514, PMID:19717140, PMID:28257918, PMID:29045497 NCBI chr 3:92,518,679...92,665,731
Ensembl chr 3:92,640,752...92,665,644 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 multiple interactions EXP Ceftriaxone inhibits the reaction [Cocaine results in decreased expression of SLC7A11 protein] CTD PMID:19717140 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Ceftriaxone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TNF protein]; ropinirole promotes the reaction [Ceftriaxone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TNF protein]] CTD PMID:25053526 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
chloromethylisothiazolinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta increases metabolic processing ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of ACTB protein CTD PMID:29267982 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases activity ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased activity of AKR1C2 promoter CTD PMID:21195160 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341 		JBrowse link
G Alb albumin increases metabolic processing ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of ALB protein CTD PMID:29267982 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased expression of CCL4 protein CTD PMID:18353026 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355 		JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 multiple interactions ISO [5-chloro-2-methyl-4-isothiazolin-3-one co-treated with 2-methyl-4-isothiazolin-3-one] results in decreased expression of CXCL14 protein CTD PMID:31734321 NCBI chr17:9,109,731...9,117,754
Ensembl chr17:9,109,731...9,117,750 		JBrowse link
G Dhx9 DExH-box helicase 9 increases metabolic processing ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of DHX9 protein CTD PMID:29267982 NCBI chr13:70,885,503...70,922,278
Ensembl chr13:70,885,504...70,922,245 		JBrowse link
G Hbb hemoglobin subunit beta increases metabolic processing ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of HBB protein CTD PMID:29267982 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725 		JBrowse link
G Hist1h4m histone cluster 1, H4m increases metabolic processing ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of H4C1 protein CTD PMID:29267982 Ensembl chr17:44,815,684...44,815,995 JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased expression of HMOX1 mRNA CTD PMID:20713136 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K increases metabolic processing ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of HNRNPK protein CTD PMID:29267982 NCBI chr17:6,664,730...6,676,753
Ensembl chr17:6,665,659...6,676,654 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases metabolic processing ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of HSP90AA1 protein CTD PMID:29267982 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases metabolic processing ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of HSPA1A protein CTD PMID:29267982 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases metabolic processing ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of HSPA8 protein CTD PMID:29267982 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179 		JBrowse link
G Il2 interleukin 2 increases secretion ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased secretion of IL2 protein CTD PMID:22245253 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854 		JBrowse link
G Il6 interleukin 6 increases secretion ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased secretion of IL6 protein CTD PMID:22245253 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Lmna lamin A/C increases metabolic processing ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of LMNA protein CTD PMID:29267982 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516 		JBrowse link
G Myh9 myosin, heavy chain 9 increases metabolic processing ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of MYH9 protein CTD PMID:29267982 NCBI chr 7:118,740,005...118,792,507
Ensembl chr 7:118,741,110...118,792,625 		JBrowse link
G Notch3 notch receptor 3 increases expression ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased expression of NOTCH3 mRNA CTD PMID:20713136 NCBI chr 7:14,138,495...14,189,688
Ensembl chr 7:14,138,495...14,189,688 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased expression of NQO1 mRNA CTD PMID:20491607 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180 		JBrowse link
G Pkm pyruvate kinase M1/2 increases metabolic processing ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased metabolism of PKM protein CTD PMID:29267982 NCBI chr 8:64,480,963...64,502,957
Ensembl chr 8:64,481,172...64,502,722 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO 5-chloro-2-methyl-4-isothiazolin-3-one results in increased expression of PMAIP1 mRNA CTD PMID:20713136 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO [5-chloro-2-methyl-4-isothiazolin-3-one co-treated with 2-methyl-4-isothiazolin-3-one] results in increased expression of VEGFA protein CTD PMID:25617811 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
clothianidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca13 ATP binding cassette subfamily A member 13 increases expression ISO clothianidin results in increased expression of ABCA13 mRNA CTD PMID:31626844 NCBI chr14:89,384,512...89,876,748
Ensembl chr14:89,384,512...89,714,917 		JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 decreases expression ISO clothianidin results in decreased expression of ABCB6 mRNA CTD PMID:29044138 NCBI chr 9:82,373,950...82,382,228
Ensembl chr 9:82,373,946...82,382,272 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO clothianidin results in increased expression of ABCC1 mRNA CTD PMID:31626844 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196 		JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 decreases expression ISO clothianidin results in decreased expression of ABCD2 mRNA CTD PMID:31626844 NCBI chr 7:132,294,564...132,343,169
Ensembl chr 7:132,294,562...132,343,169 		JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 decreases expression ISO clothianidin results in decreased expression of ABCD3 mRNA CTD PMID:31626844 NCBI chr 2:225,335,708...225,389,120
Ensembl chr 2:225,335,718...225,389,120 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 decreases expression ISO clothianidin results in decreased expression of ABCG1 mRNA CTD PMID:29044138 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489 		JBrowse link
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B decreases expression ISO clothianidin results in decreased expression of ABHD4 mRNA CTD PMID:31626844 NCBI chr15:32,888,233...32,906,861
Ensembl chr15:32,894,938...32,906,850 		JBrowse link
G Abi3bp ABI family member 3 binding protein decreases expression ISO clothianidin results in decreased expression of ABI3BP mRNA CTD PMID:31626844 NCBI chr11:46,206,932...46,422,791
Ensembl chr11:46,208,075...46,369,577 		JBrowse link
G Adcy2 adenylate cyclase 2 increases expression ISO clothianidin results in increased expression of ADCY2 mRNA CTD PMID:31626844 NCBI chr 1:37,043,071...37,698,390
Ensembl chr 1:37,507,276...37,698,390 		JBrowse link
G Adcy4 adenylate cyclase 4 decreases expression ISO clothianidin results in decreased expression of ADCY4 mRNA CTD PMID:29044138 NCBI chr15:34,453,917...34,469,779
Ensembl chr15:34,453,915...34,469,746 		JBrowse link
G Adgrb2 adhesion G protein-coupled receptor B2 decreases expression ISO clothianidin results in decreased expression of ADGRB2 mRNA CTD PMID:31626844 NCBI chr 5:148,168,530...148,231,587
Ensembl chr 5:148,193,710...148,231,587 		JBrowse link
G Adgrf5 adhesion G protein-coupled receptor F5 decreases expression ISO clothianidin results in decreased expression of ADGRF5 mRNA CTD PMID:31626844 NCBI chr 9:20,091,121...20,195,706
Ensembl chr 9:20,091,099...20,195,566 		JBrowse link
G Adgrg6 adhesion G protein-coupled receptor G6 decreases expression ISO clothianidin results in decreased expression of ADGRG6 mRNA CTD PMID:31626844 NCBI chr 1:8,593,342...8,751,540
Ensembl chr 1:8,593,075...8,751,198 		JBrowse link
G Adrb2 adrenoceptor beta 2 decreases expression ISO clothianidin results in decreased expression of ADRB2 mRNA CTD PMID:31626844 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834 		JBrowse link
G Aff1-as1 AFF1 antisense RNA 1 decreases expression ISO clothianidin results in decreased expression of C4ORF36 mRNA CTD PMID:31626844 NCBI chr14:7,581,189...7,636,823
Ensembl chr14:7,581,189...7,636,822 		JBrowse link
G Agbl3 ATP/GTP binding protein-like 3 increases expression ISO clothianidin results in increased expression of AGBL3 mRNA CTD PMID:31626844 NCBI chr 4:62,293,158...62,377,740
Ensembl chr 4:62,299,044...62,376,533 		JBrowse link
G Amz1 archaelysin family metallopeptidase 1 increases expression ISO clothianidin results in increased expression of AMZ1 mRNA CTD PMID:31626844 NCBI chr12:15,975,211...16,011,238
Ensembl chr12:15,976,079...16,002,788 		JBrowse link
G Ank3 ankyrin 3 decreases expression ISO clothianidin results in decreased expression of ANK3 mRNA CTD PMID:31626844 NCBI chr20:19,948,767...20,480,628
Ensembl chr20:20,105,047...20,480,623 		JBrowse link
G Ankrd37 ankyrin repeat domain 37 decreases expression ISO clothianidin results in decreased expression of ANKRD37 mRNA CTD PMID:31626844 NCBI chr16:49,463,016...49,465,905
Ensembl chr16:49,462,889...49,465,888 		JBrowse link
G Aplf aprataxin and PNKP like factor increases expression ISO clothianidin results in increased expression of APLF mRNA CTD PMID:31626844 NCBI chr 4:119,514,822...119,568,764
Ensembl chr 4:119,514,840...119,568,736 		JBrowse link
G Arhgap17 Rho GTPase activating protein 17 increases expression ISO clothianidin results in increased expression of ARHGAP17 mRNA CTD PMID:31626844 NCBI chr 1:193,239,036...193,328,425
Ensembl chr 1:193,239,040...193,328,371 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 increases expression ISO clothianidin results in increased expression of ARHGEF2 mRNA CTD PMID:31626844 NCBI chr 2:187,964,100...188,022,847
Ensembl chr 2:187,977,008...188,021,377 		JBrowse link
G Arih2os ARIH2 opposite strand lncRNA increases expression ISO clothianidin results in increased expression of ARIH2OS mRNA CTD PMID:31626844 NCBI chr 8:117,443,121...117,447,405 JBrowse link
G Arl11 ADP-ribosylation factor like GTPase 11 increases expression ISO clothianidin results in increased expression of ARL11 mRNA CTD PMID:31626844 NCBI chr15:41,639,985...41,645,685
Ensembl chr15:41,643,541...41,645,685 		JBrowse link
G Arl6 ADP-ribosylation factor like GTPase 6 increases expression ISO clothianidin results in increased expression of ARL6 mRNA CTD PMID:31626844 NCBI chr11:42,858,476...42,884,324
Ensembl chr11:42,858,478...42,884,603 		JBrowse link
G Asb11 ankyrin repeat and SOCS box containing 11 increases expression ISO clothianidin results in increased expression of ASB11 mRNA CTD PMID:31626844 NCBI chr  X:31,758,294...31,781,863
Ensembl chr  X:31,700,633...31,780,425 		JBrowse link
G Asphd1 aspartate beta-hydroxylase domain containing 1 decreases expression ISO clothianidin results in decreased expression of ASPHD1 mRNA CTD PMID:31626844 NCBI chr 1:198,379,060...198,382,982
Ensembl chr 1:198,379,022...198,382,614 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 decreases expression ISO clothianidin results in decreased expression of ATP1A2 mRNA CTD PMID:29044138 NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629 		JBrowse link
G Atp23 ATP23 metallopeptidase and ATP synthase assembly factor homolog increases expression ISO clothianidin results in increased expression of XRCC6BP1 mRNA CTD PMID:31626844 NCBI chr 7:70,183,625...70,198,655
Ensembl chr 7:70,183,625...70,198,655 		JBrowse link
G Atp2b3 ATPase plasma membrane Ca2+ transporting 3 decreases expression ISO clothianidin results in decreased expression of ATP2B3 mRNA CTD PMID:29044138 NCBI chr  X:157,236,400...157,312,028
Ensembl chr  X:157,239,306...157,312,028 		JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 increases expression ISO clothianidin results in increased expression of ATP6V0D2 mRNA CTD PMID:31626844 NCBI chr 5:33,843,591...33,892,446
Ensembl chr 5:33,843,519...33,892,462 		JBrowse link
G Awat1 acyl-CoA wax alcohol acyltransferase 1 increases expression ISO clothianidin results in increased expression of AWAT1 mRNA CTD PMID:31626844 NCBI chr  X:70,408,124...70,414,369
Ensembl chr  X:70,408,064...70,414,368 		JBrowse link
G Axin1 axin 1 decreases expression ISO clothianidin results in decreased expression of AXIN1 mRNA CTD PMID:31626844
G Azin2 antizyme inhibitor 2 decreases expression ISO clothianidin results in decreased expression of AZIN2 mRNA CTD PMID:29044138 NCBI chr 5:147,120,128...147,148,576
Ensembl chr 5:147,120,129...147,148,291 		JBrowse link
G Barhl1 BarH-like homeobox 1 increases expression ISO clothianidin results in increased expression of BARHL1 mRNA CTD PMID:31626844 NCBI chr 3:7,491,234...7,498,555
Ensembl chr 3:7,491,234...7,498,555 		JBrowse link
G Bcr BCR activator of RhoGEF and GTPase decreases expression ISO clothianidin results in decreased expression of BCR mRNA CTD PMID:31626844 NCBI chr20:14,421,250...14,546,406
Ensembl chr20:14,421,141...14,545,772 		JBrowse link
G Bicd2 BICD cargo adaptor 2 decreases expression ISO clothianidin results in decreased expression of BICD2 mRNA CTD PMID:31626844 NCBI chr17:15,673,649...15,718,035
Ensembl chr17:15,673,650...15,718,035 		JBrowse link
G Bricd5 BRICHOS domain containing 5 decreases expression ISO clothianidin results in decreased expression of BRICD5 mRNA CTD PMID:29044138 NCBI chr10:13,839,599...13,841,132
Ensembl chr10:13,839,956...13,841,018 		JBrowse link
G C2cd4b C2 calcium-dependent domain containing 4B increases expression ISO clothianidin results in increased expression of C2CD4B mRNA CTD PMID:31626844 NCBI chr 8:73,589,848...73,594,516
Ensembl chr 8:73,593,310...73,594,332 		JBrowse link
G Ca3 carbonic anhydrase 3 increases expression ISO clothianidin results in increased expression of CA3 mRNA CTD PMID:31626844 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410 		JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 decreases expression ISO clothianidin results in decreased expression of CACNB2 mRNA CTD PMID:31626844 NCBI chr17:81,673,862...82,019,219
Ensembl chr17:81,798,756...82,017,682 		JBrowse link
G Calhm3 calcium homeostasis modulator 3 increases expression ISO clothianidin results in increased expression of CALHM3 mRNA CTD PMID:31626844 NCBI chr 1:266,928,596...266,935,678
Ensembl chr 1:266,929,299...266,934,303 		JBrowse link
G Capn5 calpain 5 increases expression ISO clothianidin results in increased expression of CAPN5 mRNA CTD PMID:29044138 NCBI chr 1:163,073,134...163,129,736
Ensembl chr 1:163,073,124...163,129,641 		JBrowse link
G Carmil1 capping protein regulator and myosin 1 linker 1 decreases expression ISO clothianidin results in decreased expression of LRRC16A mRNA CTD PMID:31626844 NCBI chr17:43,050,282...43,339,403
Ensembl chr17:43,050,789...43,339,403 		JBrowse link
G Carmil3 capping protein regulator and myosin 1 linker 3 increases expression ISO clothianidin results in increased expression of CARMIL3 mRNA CTD PMID:29044138 NCBI chr15:34,167,146...34,184,799
Ensembl chr15:34,167,945...34,184,799 		JBrowse link
G Ccdc17 coiled-coil domain containing 17 decreases expression ISO clothianidin results in decreased expression of CCDC17 mRNA CTD PMID:29044138 NCBI chr 5:135,440,276...135,445,794
Ensembl chr 5:135,442,031...135,445,791 		JBrowse link
G Ccdc8 coiled-coil domain containing 8 increases expression ISO clothianidin results in increased expression of CCDC8 mRNA CTD PMID:31626844 NCBI chr 1:78,933,372...78,936,700
Ensembl chr 1:78,933,372...78,936,700 		JBrowse link
G Ccser1 coiled-coil serine-rich protein 1 decreases expression ISO clothianidin results in decreased expression of CCSER1 mRNA CTD PMID:31626844 NCBI chr 4:91,235,885...92,516,800
Ensembl chr 4:91,373,942...91,972,325 		JBrowse link
G Cd226 CD226 molecule decreases expression ISO clothianidin results in decreased expression of CD226 mRNA CTD PMID:31626844 NCBI chr18:86,299,392...86,394,772
Ensembl chr18:86,299,463...86,394,765 		JBrowse link
G Cd34 CD34 molecule increases expression ISO clothianidin results in increased expression of CD34 mRNA CTD PMID:31626844 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647 		JBrowse link
G Cd74 CD74 molecule increases expression ISO clothianidin results in increased expression of CD74 mRNA CTD PMID:31626844 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849 		JBrowse link
G Cd8b CD8b molecule increases expression ISO clothianidin results in increased expression of CD8B mRNA CTD PMID:31626844 NCBI chr 4:99,185,960...99,201,887
Ensembl chr 4:99,185,885...99,202,023 		JBrowse link
G Cdh8 cadherin 8 decreases expression ISO clothianidin results in decreased expression of CDH8 mRNA CTD PMID:31626844 NCBI chr19:6,031,654...6,431,502
Ensembl chr19:6,046,665...6,426,216 		JBrowse link
G Ceacam6 CEA cell adhesion molecule 6 increases expression ISO clothianidin results in increased expression of CEACAM6 mRNA CTD PMID:31626844 NCBI chr 1:81,683,500...81,701,230
Ensembl chr 1:81,683,463...81,701,317 		JBrowse link
G Cemip cell migration inducing hyaluronidase increases expression ISO clothianidin results in increased expression of CEMIP mRNA CTD PMID:31626844 NCBI chr 1:146,069,774...146,226,320
Ensembl chr 1:146,069,771...146,226,462 		JBrowse link
G Ces2h carboxylesterase 2H multiple interactions ISO [clothianidin co-treated with thiacloprid] results in increased expression of CES2 protein CTD PMID:32201337 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156 		JBrowse link
G Cfap94 cilia and flagella associated protein 94 decreases expression ISO clothianidin results in decreased expression of CFAP94 mRNA CTD PMID:31626844 NCBI chr 4:179,440,984...179,476,965
Ensembl chr 4:179,440,953...179,477,070 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO clothianidin promotes the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:21538459 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP
ISO		 clothianidin results in increased activity of [NACHRA1 protein co-treated with CHRNB2 protein]; clothianidin results in increased activity of [NACHRA8 protein co-treated with CHRNB2 protein]
clothianidin promotes the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]		 CTD PMID:16981889, PMID:21538459, PMID:25459289 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785 		JBrowse link
G Chst3 carbohydrate sulfotransferase 3 increases expression ISO clothianidin results in increased expression of CHST3 mRNA CTD PMID:29044138 NCBI chr20:29,731,828...29,768,656
Ensembl chr20:29,731,816...29,738,506 		JBrowse link
G Clec3b C-type lectin domain family 3, member B increases expression ISO clothianidin results in increased expression of CLEC3B mRNA CTD PMID:31626844 NCBI chr 8:132,241,016...132,248,066
Ensembl chr 8:132,241,134...132,246,694 		JBrowse link
G Cmtm5 CKLF-like MARVEL transmembrane domain containing 5 increases expression ISO clothianidin results in increased expression of CMTM5 mRNA CTD PMID:31626844 NCBI chr15:33,600,016...33,602,839
Ensembl chr15:33,600,102...33,602,834 		JBrowse link
G Cntnap1 contactin associated protein 1 decreases expression ISO clothianidin results in decreased expression of CNTNAP1 mRNA CTD PMID:31626844 NCBI chr10:89,087,904...89,103,615
Ensembl chr10:89,089,646...89,103,614 		JBrowse link
G Col12a1 collagen type XII alpha 1 chain decreases expression ISO clothianidin results in decreased expression of COL12A1 mRNA CTD PMID:31626844 NCBI chr 8:87,042,820...87,150,701
Ensembl chr 8:87,040,799...87,158,368 		JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO clothianidin results in decreased expression of COL1A1 mRNA CTD PMID:29044138 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789 		JBrowse link
G Col6a2 collagen type VI alpha 2 chain increases expression ISO clothianidin results in increased expression of COL6A2 mRNA CTD PMID:31626844 NCBI chr20:12,773,472...12,801,179
Ensembl chr20:12,773,427...12,801,180 		JBrowse link
G Col7a1 collagen type VII alpha 1 chain decreases expression ISO clothianidin results in decreased expression of COL7A1 mRNA CTD PMID:29044138 NCBI chr 8:117,694,441...117,726,844
Ensembl chr 8:117,694,605...117,726,844 		JBrowse link
G Coro2b coronin 2B decreases expression ISO clothianidin results in decreased expression of CORO2B mRNA CTD PMID:31626844 NCBI chr 8:67,374,617...67,492,490
Ensembl chr 8:67,376,294...67,492,037 		JBrowse link
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 decreases expression ISO clothianidin results in decreased expression of CPEB3 mRNA CTD PMID:31626844 NCBI chr 1:255,660,165...255,842,671
Ensembl chr 1:255,665,238...255,815,733 		JBrowse link
G Cpne4 copine 4 increases expression ISO clothianidin results in increased expression of CPNE4 mRNA CTD PMID:31626844 NCBI chr 8:113,105,814...113,586,429
Ensembl chr 8:113,105,814...113,586,418 		JBrowse link
G Csmd1 CUB and Sushi multiple domains 1 increases expression ISO clothianidin results in increased expression of CSMD1 mRNA CTD PMID:31626844 NCBI chr16:77,152,823...78,850,222
Ensembl chr16:78,539,489...78,850,222 		JBrowse link
G Cxadr CXADR, Ig-like cell adhesion molecule increases expression ISO clothianidin results in increased expression of CXADR mRNA CTD PMID:29044138 NCBI chr11:16,826,269...16,873,564
Ensembl chr11:16,826,399...16,873,562 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression		 ISO [clothianidin co-treated with enilconazole] results in increased expression of CYP1A2 mRNA; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in increased expression of CYP1A2 mRNA
clothianidin results in increased expression of CYP1A2 mRNA		 CTD PMID:32201337 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [clothianidin co-treated with enilconazole] results in increased expression of CYP1B1 protein CTD PMID:32201337 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO [clothianidin co-treated with thiacloprid] results in increased expression of CYP2B6 protein CTD PMID:32201337 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression
multiple interactions		 ISO clothianidin results in decreased expression of CYP2E1 mRNA
[clothianidin co-treated with enilconazole] results in decreased expression of CYP2E1 mRNA; [clothianidin co-treated with thiacloprid] results in increased expression of CYP2E1 protein; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in decreased expression of CYP2E1 mRNA; [thiacloprid co-treated with clothianidin] results in decreased expression of CYP2E1 mRNA		 CTD PMID:32201337 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions
increases expression		 ISO [clothianidin co-treated with enilconazole] results in increased expression of CYP3A5 protein; [thiacloprid co-treated with clothianidin] results in increased expression of CYP3A5 mRNA
clothianidin results in increased expression of CYP3A5 mRNA		 CTD PMID:32201337 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399 		JBrowse link
G Cyth4 cytohesin 4 increases expression ISO clothianidin results in increased expression of CYTH4 mRNA CTD PMID:31626844 NCBI chr 7:119,820,521...119,845,003
Ensembl chr 7:119,820,537...119,845,003 		JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 decreases expression ISO clothianidin results in decreased expression of DACT1 mRNA CTD PMID:31626844 NCBI chr 6:93,740,440...93,751,003
Ensembl chr 6:93,740,586...93,749,809 		JBrowse link
G Defa5 defensin alpha 5 decreases expression ISO clothianidin results in decreased expression of DEFA5 mRNA CTD PMID:31626844 NCBI chr16:75,338,050...75,340,401
Ensembl chr16:75,338,052...75,340,360 		JBrowse link
G Des desmin increases expression ISO clothianidin results in increased expression of DES mRNA CTD PMID:31626844 NCBI chr 9:82,556,574...82,564,288
Ensembl chr 9:82,556,573...82,564,294 		JBrowse link
G Dgkd diacylglycerol kinase, delta increases expression ISO clothianidin results in increased expression of DGKD mRNA CTD PMID:31626844 NCBI chr 9:94,980,328...95,071,531
Ensembl chr 9:94,980,409...95,069,714 		JBrowse link
G Dio3 iodothyronine deiodinase 3 increases expression ISO clothianidin results in increased expression of DIO3 mRNA CTD PMID:31626844 NCBI chr 6:134,627,278...134,629,139
Ensembl chr 6:134,627,278...134,629,138 		JBrowse link
G Dll3 delta like canonical Notch ligand 3 decreases expression ISO clothianidin results in decreased expression of DLL3 mRNA CTD PMID:31626844 NCBI chr 1:85,485,875...85,493,683
Ensembl chr 1:85,485,289...85,493,685 		JBrowse link
G Dnajc21 DnaJ heat shock protein family (Hsp40) member C21 increases expression ISO clothianidin results in increased expression of DNAJC21 mRNA CTD PMID:31626844 NCBI chr 2:60,419,446...60,446,656
Ensembl chr 2:60,419,525...60,446,510 		JBrowse link
G Dnajc28 DnaJ heat shock protein family (Hsp40) member C28 decreases expression ISO clothianidin results in decreased expression of DNAJC28 mRNA CTD PMID:31626844 NCBI chr11:31,770,164...31,772,984
Ensembl chr11:31,770,165...31,772,984 		JBrowse link
G Dnajc5g DnaJ heat shock protein family (Hsp40) member C5 gamma increases expression ISO clothianidin results in increased expression of DNAJC5G mRNA CTD PMID:31626844 NCBI chr 6:26,625,526...26,629,651
Ensembl chr 6:26,625,525...26,629,654 		JBrowse link
G Dnase1l2 deoxyribonuclease 1 like 2 decreases expression ISO clothianidin results in decreased expression of DNASE1L2 mRNA CTD PMID:29044138 NCBI chr10:13,812,335...13,814,514
Ensembl chr10:13,812,707...13,814,304 		JBrowse link
G Dnhd1 dynein heavy chain domain 1 decreases expression ISO clothianidin results in decreased expression of DNHD1 mRNA CTD PMID:29044138 NCBI chr 1:170,473,792...170,570,220
Ensembl chr 1:170,471,272...170,565,063 		JBrowse link
G Dok5 docking protein 5 decreases expression ISO clothianidin results in decreased expression of DOK5 mRNA CTD PMID:31626844 NCBI chr 3:168,345,116...168,482,445
Ensembl chr 3:168,345,152...168,482,441 		JBrowse link
G Dus3l dihydrouridine synthase 3-like increases expression ISO clothianidin results in increased expression of DUS3L mRNA CTD PMID:31626844 NCBI chr 9:10,289,440...10,294,213
Ensembl chr 9:10,289,446...10,293,980 		JBrowse link
G Dusp15 dual specificity phosphatase 15 increases expression ISO clothianidin results in increased expression of DUSP15 mRNA CTD PMID:29044138 NCBI chr 3:148,417,990...148,428,494
Ensembl chr 3:148,417,993...148,428,494 		JBrowse link
G Dusp16 dual specificity phosphatase 16 decreases expression ISO clothianidin results in decreased expression of DUSP16 mRNA CTD PMID:31626844 NCBI chr 4:168,470,141...168,551,346
Ensembl chr 4:168,472,412...168,517,177 		JBrowse link
G Eaf2 ELL associated factor 2 decreases expression ISO clothianidin results in decreased expression of EAF2 mRNA CTD PMID:31626844 NCBI chr11:66,878,658...66,923,092
Ensembl chr11:66,878,658...66,923,092 		JBrowse link
G Ece2 endothelin-converting enzyme 2 increases expression ISO clothianidin results in increased expression of ECE2 mRNA CTD PMID:31626844 NCBI chr11:83,948,896...83,985,429
Ensembl chr11:83,948,230...83,964,055 		JBrowse link
G Efcab12 EF-hand calcium binding domain 12 decreases expression ISO clothianidin results in decreased expression of EFCAB12 mRNA CTD PMID:29044138 NCBI chr 4:147,720,813...147,743,342
Ensembl chr 4:147,721,045...147,742,114 		JBrowse link
G Efs embryonal Fyn-associated substrate decreases expression ISO clothianidin results in decreased expression of EFS mRNA CTD PMID:31626844 NCBI chr15:33,579,952...33,590,217
Ensembl chr15:33,578,381...33,589,522 		JBrowse link
G Eif3f eukaryotic translation initiation factor 3, subunit F decreases expression ISO clothianidin results in decreased expression of EIF3F mRNA CTD PMID:31626844 NCBI chr 1:173,532,826...173,541,806
Ensembl chr 1:173,532,803...173,541,847 		JBrowse link
G Elf1 E74 like ETS transcription factor 1 increases expression ISO clothianidin results in increased expression of ELF1 mRNA CTD PMID:31626844 NCBI chr15:61,772,544...61,868,442
Ensembl chr15:61,826,711...61,868,343 		JBrowse link
G Elmod1 ELMO domain containing 1 decreases expression ISO clothianidin results in decreased expression of ELMOD1 mRNA CTD PMID:31626844 NCBI chr 8:58,486,078...58,542,884
Ensembl chr 8:58,486,078...58,542,844 		JBrowse link
G Enpp4 ectonucleotide pyrophosphatase/phosphodiesterase 4 increases expression ISO clothianidin results in increased expression of ENPP4 mRNA CTD PMID:29044138 NCBI chr 9:19,446,807...19,457,946
Ensembl chr 9:19,448,269...19,457,946 		JBrowse link
G Epdr1 ependymin related 1 increases expression ISO clothianidin results in increased expression of EPDR1 mRNA CTD PMID:29044138 NCBI chr17:47,397,558...47,422,183
Ensembl chr17:47,397,558...47,422,182 		JBrowse link
G Epn3 epsin 3 decreases expression ISO clothianidin results in decreased expression of EPN3 mRNA CTD PMID:31626844 NCBI chr10:82,220,762...82,231,200
Ensembl chr10:82,220,762...82,229,140 		JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 increases expression ISO clothianidin results in increased expression of EPS8 mRNA CTD PMID:29044138 NCBI chr 4:171,475,155...171,645,620
Ensembl chr 4:171,475,567...171,591,882 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 increases expression ISO clothianidin results in increased expression of ERBB3 mRNA CTD PMID:31626844 NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350 		JBrowse link
G Ergic1 endoplasmic reticulum-golgi intermediate compartment 1 increases expression ISO clothianidin results in increased expression of ERGIC1 mRNA CTD PMID:31626844 NCBI chr10:16,821,393...16,912,050
Ensembl chr10:16,821,880...16,910,641 		JBrowse link
G Exoc4 exocyst complex component 4 decreases expression ISO clothianidin results in decreased expression of EXOC4 mRNA CTD PMID:31626844 NCBI chr 4:60,549,128...61,358,305
Ensembl chr 4:60,549,197...61,355,994 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression ISO clothianidin results in decreased expression of EZH2 mRNA CTD PMID:31626844 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011 		JBrowse link
G F2 coagulation factor II decreases expression ISO clothianidin results in decreased expression of F2 mRNA CTD PMID:31626844 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031 		JBrowse link
G Fam110c family with sequence similarity 110, member C increases expression ISO clothianidin results in increased expression of FAM110C mRNA CTD PMID:31626844 NCBI chr 6:49,968,473...49,974,730
Ensembl chr 6:49,968,473...49,974,728 		JBrowse link
G Fam131a family with sequence similarity 131, member A decreases expression ISO clothianidin results in decreased expression of FAM131A mRNA CTD PMID:31626844 NCBI chr11:83,897,330...83,907,292
Ensembl chr11:83,896,873...83,905,889 		JBrowse link
G Fam151b family with sequence similarity 151, member B decreases expression ISO clothianidin results in decreased expression of FAM151B mRNA CTD PMID:31626844 NCBI chr 2:22,023,038...22,059,166
Ensembl chr 2:22,023,052...22,059,149 		JBrowse link
G Fam169a family with sequence similarity 169, member A increases expression ISO clothianidin results in increased expression of FAM169A mRNA CTD PMID:29044138 NCBI chr 2:27,884,748...27,941,069
Ensembl chr 2:27,905,535...27,938,525 		JBrowse link
G Fam229a family with sequence similarity 229, member A decreases expression ISO clothianidin results in decreased expression of FAM229A mRNA CTD PMID:29044138 NCBI chr 5:147,692,391...147,693,380
Ensembl chr 5:147,692,391...147,693,380 		JBrowse link
G Fam243a family with sequence similarity 243 member A increases expression ISO clothianidin results in increased expression of C21ORF140 mRNA CTD PMID:31626844 NCBI chr11:32,466,998...32,469,566
Ensembl chr11:32,467,001...32,469,566 		JBrowse link
G Fbxo33 F-box protein 33 decreases expression ISO clothianidin results in decreased expression of FBXO33 mRNA CTD PMID:31626844 NCBI chr 6:80,302,291...80,334,536
Ensembl chr 6:80,302,303...80,334,522 		JBrowse link
G Fcna ficolin A increases expression ISO clothianidin results in increased expression of FCN3 mRNA CTD PMID:31626844 NCBI chr 3:2,850,006...2,853,230
Ensembl chr 3:2,849,984...2,853,272 		JBrowse link
G Fer1l4 fer-1-like family member 4 decreases expression ISO clothianidin results in decreased expression of FER1L4 mRNA CTD PMID:29044138 NCBI chr 3:151,564,604...151,600,140
Ensembl chr 3:151,564,604...151,600,140 		JBrowse link
G Filip1 filamin A interacting protein 1 increases expression ISO clothianidin results in increased expression of FILIP1 mRNA CTD PMID:31626844 NCBI chr 8:87,257,312...87,453,432
Ensembl chr 8:87,256,264...87,419,564 		JBrowse link
G Fitm1 fat storage-inducing transmembrane protein 1 increases expression ISO clothianidin results in increased expression of FITM1 mRNA CTD PMID:31626844 NCBI chr15:34,251,805...34,253,074
Ensembl chr15:34,251,606...34,253,073 		JBrowse link
G Folr2 folate receptor beta increases expression ISO clothianidin results in increased expression of FOLR2 mRNA CTD PMID:31626844 NCBI chr 1:166,915,045...166,933,377
Ensembl chr 1:166,915,045...166,919,302 		JBrowse link
G Foxo1 forkhead box O1 increases expression ISO clothianidin results in increased expression of FOXO1 mRNA CTD PMID:31626844 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016 		JBrowse link
G Foxo4 forkhead box O4 decreases expression ISO clothianidin results in decreased expression of FOXO4 mRNA CTD PMID:29044138 NCBI chr  X:71,155,284...71,162,158
Ensembl chr  X:71,155,601...71,162,158 		JBrowse link
G Fyb1 FYN binding protein 1 decreases expression ISO clothianidin results in decreased expression of FYB mRNA CTD PMID:31626844 NCBI chr 2:55,834,904...55,983,805
Ensembl chr 2:55,835,151...55,983,804 		JBrowse link
G Gask1a golgi associated kinase 1A increases expression ISO clothianidin results in increased expression of FAM198A mRNA CTD PMID:31626844 NCBI chr 8:130,581,072...130,614,118
Ensembl chr 8:130,581,062...130,612,510 		JBrowse link
G Ghrhr growth hormone releasing hormone receptor increases expression ISO clothianidin results in increased expression of GHRHR mRNA CTD PMID:31626844 NCBI chr 4:85,587,321...85,602,389
Ensembl chr 4:85,588,595...85,601,666 		JBrowse link
G Gli1 GLI family zinc finger 1 decreases expression ISO clothianidin results in decreased expression of GLI1 mRNA CTD PMID:31626844 NCBI chr 7:70,620,794...70,633,171
Ensembl chr 7:70,620,766...70,630,338 		JBrowse link
G Gngt1 G protein subunit gamma transducin 1 decreases expression ISO clothianidin results in decreased expression of GNGT1 mRNA CTD PMID:31626844 NCBI chr 4:28,972,339...28,975,419
Ensembl chr 4:28,972,434...28,975,419 		JBrowse link
G Gpc6 glypican 6 increases expression ISO clothianidin results in increased expression of GPC6 mRNA CTD PMID:31626844 NCBI chr15:102,164,091...103,174,721
Ensembl chr15:102,164,751...103,170,847 		JBrowse link
G Gpcpd1 glycerophosphocholine phosphodiesterase 1 increases expression ISO clothianidin results in increased expression of GPCPD1 mRNA CTD PMID:31626844 NCBI chr 3:125,169,131...125,213,598
Ensembl chr 3:125,169,135...125,213,607 		JBrowse link
G Gpihbp1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 increases expression ISO clothianidin results in increased expression of GPIHBP1 mRNA CTD PMID:31626844 NCBI chr 7:116,632,496...116,635,543
Ensembl chr 7:116,632,506...116,634,293 		JBrowse link
G Gpx4 glutathione peroxidase 4 decreases expression ISO clothianidin results in decreased expression of GPX4 protein CTD PMID:25960033 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154 		JBrowse link
G Gramd1c GRAM domain containing 1C decreases expression ISO clothianidin results in decreased expression of GRAMD1C mRNA CTD PMID:31626844 NCBI chr11:61,609,370...61,659,355
NCBI chr11:62,580,983...62,634,961
Ensembl chr11:61,605,937...62,634,803 		JBrowse link
G Gramd2a GRAM domain containing 2A decreases expression ISO clothianidin results in decreased expression of GRAMD2 mRNA CTD PMID:31626844 NCBI chr 8:64,503,058...64,539,149
Ensembl chr 8:64,531,594...64,539,367 		JBrowse link
G Gskip GSK3B interacting protein increases expression ISO clothianidin results in increased expression of GSKIP mRNA CTD PMID:29044138 NCBI chr 6:129,512,950...129,536,320
Ensembl chr 6:129,519,709...129,536,221 		JBrowse link
G Gtf3c5 general transcription factor IIIC subunit 5 increases expression ISO clothianidin results in increased expression of GTF3C5 mRNA CTD PMID:31626844 NCBI chr 3:7,144,354...7,164,678
Ensembl chr 3:7,144,250...7,164,654 		JBrowse link
G Gtsf1l gametocyte specific factor 1-like increases expression ISO clothianidin results in increased expression of GTSF1L mRNA CTD PMID:31626844 NCBI chr 3:159,452,355...159,453,243 JBrowse link
G Gypc glycophorin C (Gerbich blood group) increases expression ISO clothianidin results in increased expression of GYPC mRNA CTD PMID:31626844 NCBI chr18:25,312,386...25,344,614
Ensembl chr18:25,312,387...25,344,614 		JBrowse link
G H1f7 H1.7 linker histone increases expression ISO clothianidin results in increased expression of H1-7 mRNA CTD PMID:31626844 NCBI chr 7:139,871,491...139,872,858
Ensembl chr 7:139,871,479...139,872,900 		JBrowse link
G Hacd2 3-hydroxyacyl-CoA dehydratase 2 increases expression ISO clothianidin results in increased expression of HACD2 mRNA CTD PMID:29044138 NCBI chr11:68,893,684...68,985,635
Ensembl chr11:68,894,445...68,989,988 		JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase increases expression ISO clothianidin results in increased expression of HCK mRNA CTD PMID:31626844 NCBI chr 3:148,579,917...148,623,026
Ensembl chr 3:148,579,920...148,623,033 		JBrowse link
G Hectd2 HECT domain E3 ubiquitin protein ligase 2 increases expression ISO clothianidin results in increased expression of HECTD2 mRNA CTD PMID:29044138 NCBI chr 1:255,186,729...255,254,307
Ensembl chr 1:255,185,629...255,254,307 		JBrowse link
G Hecw2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 decreases expression ISO clothianidin results in decreased expression of HECW2 mRNA CTD PMID:31626844 NCBI chr 9:60,451,476...60,843,160
Ensembl chr 9:60,457,215...60,672,246 		JBrowse link
G Hgf hepatocyte growth factor decreases expression ISO clothianidin results in decreased expression of HGF mRNA CTD PMID:31626844 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362 		JBrowse link
G Hid1 HID1 domain containing decreases expression ISO clothianidin results in decreased expression of HID1 mRNA CTD PMID:31626844 NCBI chr10:103,899,160...103,919,649
Ensembl chr10:103,899,150...103,919,605 		JBrowse link
G Hmbs hydroxymethylbilane synthase increases expression ISO clothianidin results in increased expression of HMBS mRNA CTD PMID:31626844 NCBI chr 8:48,667,278...48,674,673
Ensembl chr 8:48,667,275...48,674,748 		JBrowse link
G Hnf1b HNF1 homeobox B increases expression ISO clothianidin results in increased expression of HNF1B mRNA CTD PMID:31626844 NCBI chr10:71,159,863...71,218,902
Ensembl chr10:71,159,869...71,218,902 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha increases expression ISO clothianidin results in increased expression of HNF4A mRNA CTD PMID:31626844 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K decreases expression ISO clothianidin results in decreased expression of HNRNPK mRNA CTD PMID:31626844 NCBI chr17:6,664,730...6,676,753
Ensembl chr17:6,665,659...6,676,654 		JBrowse link
G Il17re interleukin 17 receptor E decreases expression ISO clothianidin results in decreased expression of IL17RE mRNA CTD PMID:29044138 NCBI chr 4:145,413,157...145,426,608
Ensembl chr 4:145,413,230...145,426,603 		JBrowse link
G Il18bp interleukin 18 binding protein decreases expression ISO clothianidin results in decreased expression of IL18BP mRNA CTD PMID:29044138 NCBI chr 1:167,091,521...167,095,727
Ensembl chr 1:167,091,522...167,093,560 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma increases expression ISO clothianidin results in increased expression of IL2RG mRNA CTD PMID:31626844 NCBI chr  X:71,165,378...71,169,078
Ensembl chr  X:71,162,585...71,169,865 		JBrowse link
G Immp1l inner mitochondrial membrane peptidase subunit 1 increases expression ISO clothianidin results in increased expression of IMMP1L mRNA CTD PMID:31626844 NCBI chr 3:95,955,126...96,024,316
Ensembl chr 3:95,959,703...96,024,836 		JBrowse link
G Insyn2b inhibitory synaptic factor family member 2B decreases expression ISO clothianidin results in decreased expression of FAM196B mRNA CTD PMID:31626844 NCBI chr10:19,270,956...19,392,214 JBrowse link
G Irx5 iroquois homeobox 5 decreases expression ISO clothianidin results in decreased expression of IRX5 mRNA CTD PMID:31626844 NCBI chr19:16,415,813...16,421,088
Ensembl chr19:16,415,636...16,421,191 		JBrowse link
G Itsn1 intersectin 1 decreases expression ISO clothianidin results in decreased expression of ITSN1 mRNA CTD PMID:31626844 NCBI chr11:31,943,119...32,069,249
Ensembl chr11:31,893,489...32,069,249 		JBrowse link
G Jak2 Janus kinase 2 decreases expression ISO clothianidin results in decreased expression of JAK2 mRNA CTD PMID:31626844 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509 		JBrowse link
G Kat6b lysine acetyltransferase 6B decreases expression ISO clothianidin results in decreased expression of KAT6B mRNA CTD PMID:31626844 NCBI chr15:2,811,933...2,966,833
Ensembl chr15:2,813,537...2,966,576 		JBrowse link
G Kcnc4 potassium voltage-gated channel subfamily C member 4 increases expression ISO clothianidin results in increased expression of KCNC4 mRNA CTD PMID:31626844 NCBI chr 2:210,220,908...210,241,447
Ensembl chr 2:210,220,908...210,241,455 		JBrowse link
G Kcnd3 potassium voltage-gated channel subfamily D member 3 decreases expression ISO clothianidin results in decreased expression of KCND3 mRNA CTD PMID:31626844 NCBI chr 2:207,923,775...208,140,727
Ensembl chr 2:207,923,775...208,140,727 		JBrowse link
G Kcnk1 potassium two pore domain channel subfamily K member 1 decreases expression ISO clothianidin results in decreased expression of KCNK1 mRNA CTD PMID:31626844 NCBI chr19:58,823,836...58,862,926
Ensembl chr19:58,823,814...58,862,926 		JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 decreases expression ISO clothianidin results in decreased expression of KCNMA1 mRNA CTD PMID:31626844 NCBI chr15:344,204...1,048,849
Ensembl chr15:344,360...1,047,956 		JBrowse link
G Kif7 kinesin family member 7 increases expression ISO clothianidin results in increased expression of KIF7 mRNA CTD PMID:31626844 NCBI chr 1:141,434,183...141,452,592
Ensembl chr 1:141,434,625...141,451,075 		JBrowse link
G Kifc3 kinesin family member C3 increases expression ISO clothianidin results in increased expression of KIFC3 mRNA CTD PMID:31626844 NCBI chr19:10,305,405...10,339,186
Ensembl chr19:10,320,604...10,339,178 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase increases expression ISO clothianidin results in increased expression of KIT mRNA CTD PMID:31626844 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610 		JBrowse link
G Klhdc9 kelch domain containing 9 decreases expression ISO clothianidin results in decreased expression of KLHDC9 mRNA CTD PMID:31626844 NCBI chr13:89,742,750...89,746,254
Ensembl chr13:89,742,750...89,745,835 		JBrowse link
G Kpna6 karyopherin subunit alpha 6 increases expression ISO clothianidin results in increased expression of KPNA6 mRNA CTD PMID:31626844 NCBI chr 5:147,852,738...147,867,600
Ensembl chr 5:147,850,275...147,886,615 		JBrowse link
G Krt28 keratin 28 increases expression ISO clothianidin results in increased expression of KRT28 mRNA CTD PMID:31626844 NCBI chr10:87,276,094...87,286,753
Ensembl chr10:87,276,293...87,286,387 		JBrowse link
G Ksr1 kinase suppressor of ras 1 decreases expression ISO clothianidin results in decreased expression of KSR1 mRNA CTD PMID:31626844 NCBI chr10:66,323,704...66,342,469
NCBI chr10:66,346,100...66,482,396
Ensembl chr10:66,347,358...66,482,150 		JBrowse link
G L3mbtl1 L3MBTL histone methyl-lysine binding protein 1 decreases expression ISO clothianidin results in decreased expression of L3MBTL1 mRNA CTD PMID:31626844 NCBI chr 3:159,316,580...159,348,914
Ensembl chr 3:159,321,310...159,347,631 		JBrowse link
G Lgals12 galectin 12 increases expression ISO clothianidin results in increased expression of LGALS12 mRNA CTD PMID:31626844 NCBI chr 1:222,891,626...222,903,728
Ensembl chr 1:222,891,626...222,902,320 		JBrowse link
G Lgi4 leucine-rich repeat LGI family, member 4 increases expression ISO clothianidin results in increased expression of LGI4 mRNA CTD PMID:31626844 NCBI chr 1:89,491,588...89,502,939
Ensembl chr 1:89,491,654...89,502,974 		JBrowse link
G Lim2 lens intrinsic membrane protein 2 increases expression ISO clothianidin results in increased expression of LIM2 mRNA CTD PMID:31626844 NCBI chr 1:98,495,082...98,501,248
Ensembl chr 1:98,495,082...98,501,249 		JBrowse link
G LOC100911237 zinc finger protein 420-like increases expression ISO clothianidin results in increased expression of ZNF502 mRNA CTD PMID:31626844 NCBI chr 1:31,494,043...31,519,034 JBrowse link
G LOC102551828 uncharacterized LOC102551828 decreases expression ISO clothianidin results in decreased expression of C22ORF31 mRNA CTD PMID:31626844 NCBI chr14:85,520,841...85,526,211 JBrowse link
G LOC290595 hypothetical gene supported by AF152002 decreases expression ISO clothianidin results in decreased expression of C10ORF99 mRNA CTD PMID:31626844 NCBI chr16:14,352,998...14,360,604
Ensembl chr16:14,353,459...14,360,555 		JBrowse link
G LOC691162 hypothetical protein LOC691162 decreases expression ISO clothianidin results in decreased expression of C1ORF158 mRNA CTD PMID:31626844 NCBI chr 5:162,351,021...162,369,987
Ensembl chr 5:162,351,001...162,369,990 		JBrowse link
G Lonrf1 LON peptidase N-terminal domain and ring finger 1 increases expression ISO clothianidin results in increased expression of LONRF1 mRNA CTD PMID:31626844 NCBI chr16:59,564,548...59,594,252
Ensembl chr16:59,564,419...59,593,852 		JBrowse link
G Lox lysyl oxidase increases expression ISO clothianidin results in increased expression of LOX mRNA CTD PMID:29044138 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 decreases expression ISO clothianidin results in decreased expression of LPAR1 mRNA CTD PMID:31626844 NCBI chr 5:75,557,038...75,678,067
Ensembl chr 5:75,557,042...75,676,584 		JBrowse link
G Lrig1 leucine-rich repeats and immunoglobulin-like domains 1 increases expression ISO clothianidin results in increased expression of LRIG1 mRNA CTD PMID:31626844 NCBI chr 4:126,615,998...126,717,434
Ensembl chr 4:126,617,244...126,644,895 		JBrowse link
G Lrrc74b leucine rich repeat containing 74B decreases expression ISO clothianidin results in decreased expression of LRRC74B mRNA CTD PMID:31626844 NCBI chr11:87,417,604...87,434,745
Ensembl chr11:87,418,205...87,434,482 		JBrowse link
G Luzp2 leucine zipper protein 2 increases expression ISO clothianidin results in increased expression of LUZP2 mRNA CTD PMID:31626844 NCBI chr 1:111,849,494...112,067,502
NCBI chr 1:113,419,707...113,531,330
Ensembl chr 1:111,849,998...113,527,735 		JBrowse link
G Lysmd2 LysM domain containing 2 decreases expression ISO clothianidin results in decreased expression of LYSMD2 mRNA CTD PMID:31626844 NCBI chr 8:82,560,363...82,576,662
Ensembl chr 8:82,560,761...82,577,019 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO clothianidin results in increased phosphorylation of MAPK1 protein CTD PMID:31626844 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO clothianidin results in increased phosphorylation of MAPK3 protein CTD PMID:31626844 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Mchr1 melanin-concentrating hormone receptor 1 increases expression ISO clothianidin results in increased expression of MCHR1 mRNA CTD PMID:31626844 NCBI chr 7:122,456,846...122,459,324
Ensembl chr 7:122,456,799...122,459,960 		JBrowse link
G Meioc meiosis specific with coiled-coil domain increases expression ISO clothianidin results in increased expression of MEIOC mRNA CTD PMID:31626844 NCBI chr10:90,622,954...90,641,883
Ensembl chr10:90,622,992...90,642,151 		JBrowse link
G Mettl16 methyltransferase like 16 increases expression ISO clothianidin results in increased expression of METTL16 mRNA CTD PMID:31626844 NCBI chr10:61,626,595...61,682,947
Ensembl chr10:61,626,597...61,672,136 		JBrowse link
G Mettl7a methyltransferase like 7A decreases expression ISO clothianidin results in decreased expression of METTL7A mRNA CTD PMID:29044138 NCBI chr 7:141,973,447...142,021,344
Ensembl chr 7:141,973,553...141,981,432 		JBrowse link
G Mical1 microtubule associated monooxygenase, calponin and LIM domain containing 1 increases expression ISO clothianidin results in increased expression of MICAL1 mRNA CTD PMID:31626844 NCBI chr20:46,199,981...46,211,930
Ensembl chr20:46,199,981...46,211,930 		JBrowse link
G Micall2 MICAL-like 2 decreases expression ISO clothianidin results in decreased expression of MICALL2 mRNA CTD PMID:29044138 NCBI chr12:16,988,013...17,016,794
Ensembl chr12:16,988,136...17,016,791 		JBrowse link
G Mlana melan-A increases expression ISO clothianidin results in increased expression of MLANA mRNA CTD PMID:31626844 NCBI chr 1:247,869,756...247,883,558
Ensembl chr 1:247,869,756...247,884,442 		JBrowse link
G Mmp10 matrix metallopeptidase 10 increases expression ISO clothianidin results in increased expression of MMP10 mRNA CTD PMID:31626844 NCBI chr 8:5,734,348...5,742,243
Ensembl chr 8:5,734,348...5,742,243 		JBrowse link
G Ms4a2 membrane spanning 4-domains A2 decreases expression ISO clothianidin results in decreased expression of MS4A2 mRNA CTD PMID:29044138 NCBI chr 1:227,957,363...227,965,312
Ensembl chr 1:227,957,302...227,965,386 		JBrowse link
G Mss51 MSS51 mitochondrial translational activator decreases expression ISO clothianidin results in decreased expression of MSS51 mRNA CTD PMID:29044138 NCBI chr15:4,240,203...4,252,072
Ensembl chr15:4,240,203...4,252,072 		JBrowse link
G Mtg1 mitochondrial ribosome-associated GTPase 1 decreases expression ISO clothianidin results in decreased expression of MTG1 mRNA CTD PMID:29044138 NCBI chr 1:212,606,753...212,619,493
Ensembl chr 1:212,606,777...212,619,493 		JBrowse link
G Myl4 myosin, light chain 4 decreases expression ISO clothianidin results in decreased expression of MYL4 mRNA CTD PMID:31626844 NCBI chr10:92,628,356...92,638,100
Ensembl chr10:92,628,356...92,638,100 		JBrowse link
G Myl6 myosin light chain 6 decreases expression ISO clothianidin results in decreased expression of MYL6 mRNA CTD PMID:31626844 NCBI chr 7:2,906,137...2,909,193
Ensembl chr 7:2,906,137...2,909,179 		JBrowse link
G Mylpf myosin light chain, phosphorylatable, fast skeletal muscle decreases expression ISO clothianidin results in decreased expression of MYLPF mRNA CTD PMID:31626844 NCBI chr 1:198,655,835...198,658,590
Ensembl chr 1:198,655,742...198,658,583 		JBrowse link
G Myo3b myosin IIIB increases expression ISO clothianidin results in increased expression of MYO3B mRNA CTD PMID:31626844 NCBI chr 3:56,355,433...56,717,740
Ensembl chr 3:56,355,431...56,584,547 		JBrowse link
G Myorg myogenesis regulating glycosidase increases expression ISO clothianidin results in increased expression of MYORG mRNA CTD PMID:29044138 NCBI chr 5:57,873,404...57,882,008
Ensembl chr 5:57,876,498...57,881,944 		JBrowse link
G Myt1l myelin transcription factor 1-like increases expression ISO clothianidin results in increased expression of MYT1L mRNA CTD PMID:31626844 NCBI chr 6:48,452,385...48,843,443
Ensembl chr 6:48,452,369...48,857,936 		JBrowse link
G N4bp2l1 NEDD4 binding protein 2-like 1 increases expression ISO clothianidin results in increased expression of N4BP2L1 mRNA CTD PMID:31626844 NCBI chr12:546,759...576,744
Ensembl chr12:546,760...576,746 		JBrowse link
G Nadsyn1 NAD synthetase 1 decreases expression ISO clothianidin results in decreased expression of NADSYN1 mRNA CTD PMID:31626844 NCBI chr 1:216,985,710...217,013,743
Ensembl chr 1:216,985,714...217,013,702 		JBrowse link
G Nasp nuclear autoantigenic sperm protein decreases expression ISO clothianidin results in decreased expression of NASP mRNA CTD PMID:31626844 NCBI chr 5:135,446,485...135,472,113
Ensembl chr 5:135,446,962...135,472,116 		JBrowse link
G Ndufa10 NADH:ubiquinone oxidoreductase subunit A10 increases expression ISO clothianidin results in increased expression of NDUFA10 mRNA CTD PMID:31626844 NCBI chr 9:99,617,051...99,651,827
Ensembl chr 9:99,617,052...99,651,813 		JBrowse link
G Neurod4 neuronal differentiation 4 decreases expression ISO clothianidin results in decreased expression of NEUROD4 mRNA CTD PMID:31626844 NCBI chr 7:9,699,964...9,712,067
Ensembl chr 7:9,699,961...9,711,928 		JBrowse link
G Ngef neuronal guanine nucleotide exchange factor increases expression ISO clothianidin results in increased expression of NGEF mRNA CTD PMID:31626844 NCBI chr 9:94,569,286...94,601,852
Ensembl chr 9:94,569,286...94,601,852 		JBrowse link
G Ngfr nerve growth factor receptor increases expression ISO clothianidin results in increased expression of NGFR mRNA CTD PMID:29044138 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO clothianidin results in increased expression of NOS2 mRNA CTD PMID:31626844 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression
multiple interactions		 ISO clothianidin results in decreased expression of NR0B2 mRNA
[clothianidin co-treated with enilconazole] results in decreased expression of NR0B2 mRNA		 CTD PMID:32201337 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319 		JBrowse link
G Ntn4 netrin 4 decreases expression ISO clothianidin results in decreased expression of NTN4 mRNA CTD PMID:31626844 NCBI chr 7:34,533,543...34,649,330
Ensembl chr 7:34,533,543...34,649,481 		JBrowse link
G Nts neurotensin decreases expression ISO clothianidin results in decreased expression of NTS mRNA CTD PMID:31626844 NCBI chr 7:44,111,594...44,120,998
Ensembl chr 7:44,111,151...44,121,130 		JBrowse link
G Nxnl2 nucleoredoxin-like 2 increases expression ISO clothianidin results in increased expression of NXNL2 mRNA CTD PMID:31626844 NCBI chr17:14,053,896...14,058,642
Ensembl chr17:14,053,896...14,058,642 		JBrowse link
G Nxph2 neurexophilin 2 increases expression ISO clothianidin results in increased expression of NXPH2 mRNA CTD PMID:31626844 NCBI chr 3:67,027...309,536
Ensembl chr 3:307,204...307,980 		JBrowse link
G Ocrl OCRL, inositol polyphosphate-5-phosphatase decreases expression ISO clothianidin results in decreased expression of OCRL mRNA CTD PMID:31626844 NCBI chr  X:134,742,226...134,793,411
Ensembl chr  X:134,742,356...134,792,618 		JBrowse link
G Olr59 olfactory receptor 59 increases expression ISO clothianidin results in increased expression of OR51E2 mRNA CTD PMID:31626844 NCBI chr 1:167,906,030...167,940,688
Ensembl chr 1:167,906,061...167,911,961 		JBrowse link
G Otud6b OTU deubiquitinase 6B increases expression ISO clothianidin results in increased expression of OTUD6B mRNA CTD PMID:29044138 NCBI chr 5:28,333,019...28,350,093
Ensembl chr 5:28,333,019...28,349,927 		JBrowse link
G Padi4 peptidyl arginine deiminase 4 increases expression ISO clothianidin results in increased expression of PADI4 mRNA CTD PMID:31626844 NCBI chr 5:159,260,675...159,293,906
Ensembl chr 5:159,260,675...159,293,673 		JBrowse link
G Pak5 p21 (RAC1) activated kinase 5 decreases expression ISO clothianidin results in decreased expression of PAK5 mRNA CTD PMID:31626844 NCBI chr 3:129,042,232...129,357,512
Ensembl chr 3:129,042,742...129,357,491 		JBrowse link
G Paqr8 progestin and adipoQ receptor family member 8 decreases expression ISO clothianidin results in decreased expression of PAQR8 mRNA CTD PMID:29044138 NCBI chr 9:27,005,270...27,054,591
Ensembl chr 9:27,034,022...27,051,002 		JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 decreases expression ISO clothianidin results in decreased expression of PBLD mRNA CTD PMID:31626844 NCBI chr20:27,103,300...27,118,650
Ensembl chr20:27,103,317...27,117,663 		JBrowse link
G Pcca propionyl-CoA carboxylase subunit alpha decreases expression ISO clothianidin results in decreased expression of PCCA mRNA CTD PMID:32201337 NCBI chr15:108,960,509...109,306,879
Ensembl chr15:108,960,562...109,306,603 		JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 decreases expression ISO clothianidin results in decreased expression of PCSK1 mRNA CTD PMID:31626844 NCBI chr 2:91,450,162...91,497,091
Ensembl chr 2:91,450,162...91,497,091 		JBrowse link
G Pde10a phosphodiesterase 10A decreases expression ISO clothianidin results in decreased expression of PDE10A mRNA CTD PMID:31626844 NCBI chr 1:52,360,296...52,544,448
Ensembl chr 1:52,360,296...52,544,450 		JBrowse link
G Pde1c phosphodiesterase 1C increases expression ISO clothianidin results in increased expression of PDE1C mRNA CTD PMID:31626844 NCBI chr 4:86,359,762...86,925,044
Ensembl chr 4:86,359,820...86,630,543 		JBrowse link
G Pde4dip phosphodiesterase 4D interacting protein increases expression ISO clothianidin results in increased expression of PDE4DIP mRNA CTD PMID:31626844 NCBI chr 2:199,867,965...200,066,034
Ensembl chr 2:199,867,972...200,003,443 		JBrowse link
G Pdzd7 PDZ domain containing 7 decreases expression ISO clothianidin results in decreased expression of PDZD7 mRNA CTD PMID:29044138 NCBI chr 1:264,776,393...264,796,206
Ensembl chr 1:264,776,398...264,794,938 		JBrowse link
G Peli2 pellino E3 ubiquitin protein ligase family member 2 decreases expression ISO clothianidin results in decreased expression of PELI2 mRNA CTD PMID:31626844 NCBI chr15:24,942,218...25,086,350
Ensembl chr15:24,942,218...25,083,931 		JBrowse link
G Pheta2 PH domain containing endocytic trafficking adaptor 2 increases expression ISO clothianidin results in increased expression of FAM109B mRNA CTD PMID:31626844 NCBI chr 7:123,572,153...123,578,590
Ensembl chr 7:123,573,930...123,578,551 		JBrowse link
G Pik3c2b phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta decreases expression ISO clothianidin results in decreased expression of PIK3C2B mRNA CTD PMID:31626844 NCBI chr13:49,848,939...49,909,404
Ensembl chr13:49,850,189...49,911,202 		JBrowse link
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase type 1 gamma decreases expression ISO clothianidin results in decreased expression of PIP5K1C mRNA CTD PMID:31626844 NCBI chr 7:11,267,207...11,294,291
Ensembl chr 7:11,267,218...11,294,249 		JBrowse link
G Pip5kl1 phosphatidylinositol-4-phosphate 5-kinase-like 1 decreases expression ISO clothianidin results in decreased expression of PIP5KL1 mRNA CTD PMID:29044138 NCBI chr 3:11,592,156...11,597,513
Ensembl chr 3:11,593,655...11,597,410 		JBrowse link
G Pla2g2a phospholipase A2 group IIA increases expression ISO clothianidin results in increased expression of PLA2G2A mRNA CTD PMID:31626844 NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328 		JBrowse link
G Plbd1 phospholipase B domain containing 1 decreases expression ISO clothianidin results in decreased expression of PLBD1 mRNA CTD PMID:31626844 NCBI chr 4:170,564,387...170,620,681
Ensembl chr 4:170,564,367...170,620,703 		JBrowse link
G Plcd1 phospholipase C, delta 1 increases expression ISO clothianidin results in increased expression of PLCD1 mRNA CTD PMID:31626844 NCBI chr 8:127,753,514...127,782,070
Ensembl chr 8:127,753,539...127,782,070 		JBrowse link
G Plcd3 phospholipase C, delta 3 decreases expression ISO clothianidin results in decreased expression of PLCD3 mRNA CTD PMID:31626844 NCBI chr10:91,164,778...91,186,067
Ensembl chr10:91,164,812...91,186,054 		JBrowse link
G Plcl1 phospholipase C-like 1 decreases expression ISO clothianidin results in decreased expression of PLCL1 mRNA CTD PMID:31626844 NCBI chr 9:62,016,112...62,349,244
Ensembl chr 9:62,291,405...62,349,309 		JBrowse link
G Pllp plasmolipin increases expression ISO clothianidin results in increased expression of PLLP mRNA CTD PMID:31626844 NCBI chr19:10,731,855...10,752,641
Ensembl chr19:10,731,855...10,752,641 		JBrowse link
G Pnpla1 patatin-like phospholipase domain containing 1 increases expression ISO clothianidin results in increased expression of PNPLA1 mRNA CTD PMID:31626844 NCBI chr20:6,101,061...6,143,762
Ensembl chr20:6,102,277...6,143,707 		JBrowse link
G Polr2m RNA polymerase II subunit M decreases expression ISO clothianidin results in decreased expression of POLR2M mRNA CTD PMID:31626844 NCBI chr 8:77,985,190...77,992,621
Ensembl chr 8:77,985,190...78,096,390 		JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C increases expression ISO clothianidin results in increased expression of PPP1R3C mRNA CTD PMID:29044138 NCBI chr 1:255,371,830...255,376,833
Ensembl chr 1:255,371,810...255,376,833 		JBrowse link
G Ppp3cc protein phosphatase 3 catalytic subunit gamma increases expression ISO clothianidin results in increased expression of PPP3CC mRNA CTD PMID:31626844 NCBI chr15:51,896,427...51,968,075
Ensembl chr15:51,896,615...51,967,897 		JBrowse link
G Prg3 proteoglycan 3, pro eosinophil major basic protein 2 increases expression ISO clothianidin results in increased expression of PRG3 mRNA CTD PMID:31626844 NCBI chr 3:72,395,194...72,401,254
Ensembl chr 3:72,395,218...72,401,318 		JBrowse link
G Prlr prolactin receptor decreases expression ISO clothianidin results in decreased expression of PRLR mRNA CTD PMID:29044138 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692 		JBrowse link
G Prnd prion like protein doppel increases expression ISO clothianidin results in increased expression of PRND mRNA CTD PMID:31626844 NCBI chr 3:124,543,227...124,548,548
Ensembl chr 3:124,545,364...124,545,900 		JBrowse link
G Prodh2 proline dehydrogenase 2 increases expression ISO clothianidin results in increased expression of PRODH2 mRNA CTD PMID:31626844 NCBI chr 1:88,955,125...88,968,501
Ensembl chr 1:88,955,135...88,968,501 		JBrowse link
G Prr5l proline rich 5 like increases expression ISO clothianidin results in increased expression of PRR5L mRNA CTD PMID:31626844 NCBI chr 3:91,290,207...91,461,208
Ensembl chr 3:91,291,875...91,370,167 		JBrowse link
G Prxl2b peroxiredoxin like 2B decreases expression ISO clothianidin results in decreased expression of PRXL2B mRNA CTD PMID:31626844 NCBI chr 5:172,304,799...172,307,402
Ensembl chr 5:172,304,758...172,307,431 		JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 decreases expression ISO clothianidin results in decreased expression of PSMC6 mRNA CTD PMID:31626844 NCBI chr15:19,667,453...19,688,916
Ensembl chr15:19,667,453...19,688,914 		JBrowse link
G Ptgfr prostaglandin F receptor decreases expression ISO clothianidin results in decreased expression of PTGFR mRNA CTD PMID:31626844 NCBI chr 2:257,005,813...257,039,036
Ensembl chr 2:257,005,829...257,038,105 		JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 increases expression ISO clothianidin results in increased expression of PTPN3 mRNA CTD PMID:29044138 NCBI chr 5:74,248,996...74,368,167
Ensembl chr 5:74,248,996...74,368,186 		JBrowse link
G Ptprb protein tyrosine phosphatase, receptor type, B decreases expression ISO clothianidin results in decreased expression of PTPRB mRNA CTD PMID:31626844 NCBI chr 7:59,326,484...59,431,114
Ensembl chr 7:59,326,518...59,425,718 		JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O decreases expression ISO clothianidin results in decreased expression of PTPRO mRNA CTD PMID:29044138 NCBI chr 4:171,250,766...171,461,571
Ensembl chr 4:171,250,818...171,461,677 		JBrowse link
G Qpct glutaminyl-peptide cyclotransferase increases expression ISO clothianidin results in increased expression of QPCT mRNA CTD PMID:31626844 NCBI chr 6:1,657,110...1,689,575
Ensembl chr 6:1,657,331...1,689,559 		JBrowse link
G Rag1 recombination activating 1 decreases expression ISO clothianidin results in decreased expression of RAG1 mRNA CTD PMID:31626844 NCBI chr 3:91,206,394...91,217,491
Ensembl chr 3:91,206,394...91,217,491 		JBrowse link
G Rapgefl1 Rap guanine nucleotide exchange factor like 1 decreases expression ISO clothianidin results in decreased expression of RAPGEFL1 mRNA CTD PMID:29044138 NCBI chr10:86,749,220...86,765,677
Ensembl chr10:86,763,117...86,765,675 		JBrowse link
G Rbm26 RNA binding motif protein 26 decreases expression ISO clothianidin results in decreased expression of RBM26 mRNA CTD PMID:31626844 NCBI chr15:89,262,683...89,339,323
Ensembl chr15:89,266,710...89,339,323 		JBrowse link
G Rbms1 RNA binding motif, single stranded interacting protein 1 decreases expression ISO clothianidin results in decreased expression of RBMS1 mRNA CTD PMID:31626844 NCBI chr 3:46,802,870...47,025,178
Ensembl chr 3:46,803,355...47,025,128 		JBrowse link
G Reg3g regenerating family member 3 gamma increases expression ISO clothianidin results in increased expression of REG3G mRNA CTD PMID:31626844 NCBI chr 4:109,529,679...109,532,234
Ensembl chr 4:109,529,679...109,532,234 		JBrowse link
G Rfesd Rieske (Fe-S) domain containing decreases expression ISO clothianidin results in decreased expression of RFESD mRNA CTD PMID:31626844 NCBI chr 2:2,758,382...2,784,366
Ensembl chr 2:2,769,400...2,779,109 		JBrowse link
G RGD1306227 similar to 4833420G17Rik protein increases expression ISO clothianidin results in increased expression of C5ORF34 mRNA CTD PMID:29044138 NCBI chr 2:52,333,396...52,355,044
Ensembl chr 2:52,333,396...52,355,042 		JBrowse link
G RGD1309651 similar to 1190005I06Rik protein decreases expression ISO clothianidin results in decreased expression of C16ORF74 mRNA CTD PMID:31626844 NCBI chr19:54,184,554...54,210,872
Ensembl chr19:54,184,946...54,210,515 		JBrowse link
G RGD1559804 similar to hypothetical protein 4930474N05 increases expression ISO clothianidin results in increased expression of CDRT15L2 mRNA CTD PMID:31626844 NCBI chr16:12,190,742...12,196,263
Ensembl chr16:12,191,697...12,194,118 		JBrowse link
G RGD1563060 similar to AVLV472 increases expression ISO clothianidin results in increased expression of C5ORF46 mRNA CTD PMID:31626844 NCBI chr18:38,307,889...38,329,780
Ensembl chr18:38,307,889...38,329,780 		JBrowse link
G RGD1564149 similar to Protein C21orf58 decreases expression ISO clothianidin results in decreased expression of C21ORF58 mRNA CTD PMID:31626844 NCBI chr20:12,927,310...12,938,891
Ensembl chr20:12,927,320...12,938,891 		JBrowse link
G Riiad1 regulatory subunit of type II PKA R-subunit domain containing 1 decreases expression ISO clothianidin results in decreased expression of RIIAD1 mRNA CTD PMID:31626844 NCBI chr 2:195,703,259...195,712,479
Ensembl chr 2:195,704,505...195,712,461 		JBrowse link
G Rnd1 Rho family GTPase 1 increases expression ISO clothianidin results in increased expression of RND1 mRNA CTD PMID:29044138 NCBI chr 7:140,349,138...140,356,209
Ensembl chr 7:140,349,138...140,356,209 		JBrowse link
G Rp1l1 RP1 like 1 increases expression ISO clothianidin results in increased expression of RP1L1 mRNA CTD PMID:31626844 NCBI chr15:47,344,380...47,384,461
Ensembl chr15:47,373,120...47,383,508 		JBrowse link
G Rps29 ribosomal protein S29 increases expression ISO clothianidin results in increased expression of RPS29 mRNA CTD PMID:31626844 NCBI chr 6:91,455,333...91,456,709
Ensembl chr 6:91,455,333...91,456,696
Ensembl chr 3:91,455,333...91,456,696
Ensembl chr 7:91,455,333...91,456,696 		JBrowse link
G RT1-Bb RT1 class II, locus Bb increases expression ISO clothianidin results in increased expression of HLA-DQB1 mRNA CTD PMID:31626844 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711 		JBrowse link
G S100a5 S100 calcium binding protein A5 decreases expression ISO clothianidin results in decreased expression of S100A5 mRNA CTD PMID:31626844 NCBI chr 2:189,999,669...190,005,877
Ensembl chr 2:190,003,223...190,005,871 		JBrowse link
G Sash3 SAM and SH3 domain containing 3 increases expression ISO clothianidin results in increased expression of SASH3 mRNA CTD PMID:31626844 NCBI chr  X:134,979,637...134,994,351
Ensembl chr  X:134,979,646...134,994,349 		JBrowse link
G Scn7a sodium voltage-gated channel alpha subunit 7 decreases expression ISO clothianidin results in decreased expression of SCN7A mRNA CTD PMID:31626844 NCBI chr 3:52,775,779...52,877,365
Ensembl chr 3:52,777,214...52,849,907 		JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta increases expression ISO clothianidin results in increased expression of SCNN1B mRNA CTD PMID:31626844 NCBI chr 1:191,829,547...191,883,991
Ensembl chr 1:191,829,555...191,884,298 		JBrowse link
G Sema3f semaphorin 3F decreases expression ISO clothianidin results in decreased expression of SEMA3F mRNA CTD PMID:31626844 NCBI chr 8:116,439,996...116,469,915
Ensembl chr 8:116,437,696...116,469,915 		JBrowse link
G Serp1 stress-associated endoplasmic reticulum protein 1 decreases expression ISO clothianidin results in decreased expression of SERP1 mRNA CTD PMID:31626844 NCBI chr 2:148,718,279...148,722,263
Ensembl chr 2:148,718,280...148,722,263 		JBrowse link
G Serpinc1 serpin family C member 1 decreases expression ISO clothianidin results in decreased expression of SERPINC1 mRNA CTD PMID:31626844 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192 		JBrowse link
G Serpine1 serpin family E member 1 decreases expression ISO clothianidin results in decreased expression of SERPINE1 mRNA CTD PMID:31626844 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482 		JBrowse link
G Sgcd sarcoglycan, delta increases expression ISO clothianidin results in increased expression of SGCD mRNA CTD PMID:31626844 NCBI chr10:32,062,946...32,471,454
Ensembl chr10:32,062,946...32,471,454 		JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 decreases expression ISO clothianidin results in decreased expression of SGK2 mRNA CTD PMID:29044138 NCBI chr 3:159,361,313...159,385,843
Ensembl chr 3:159,368,273...159,384,775 		JBrowse link
G Sh3tc1 SH3 domain and tetratricopeptide repeats 1 increases expression ISO clothianidin results in increased expression of SH3TC1 mRNA CTD PMID:29044138 NCBI chr14:80,184,814...80,229,207
Ensembl chr14:80,195,715...80,229,214 		JBrowse link
G Sipa1l2 signal-induced proliferation-associated 1 like 2 increases expression ISO clothianidin results in increased expression of SIPA1L2 mRNA CTD PMID:29044138 NCBI chr19:58,236,201...58,399,842
Ensembl chr19:58,236,214...58,399,816 		JBrowse link
G Slc14a1 solute carrier family 14 member 1 (Kidd blood group) decreases expression ISO clothianidin results in decreased expression of SLC14A1 mRNA CTD PMID:31626844 NCBI chr18:74,461,064...74,504,475
Ensembl chr18:74,461,055...74,485,139 		JBrowse link
G Slc17a7 solute carrier family 17 member 7 decreases expression ISO clothianidin results in decreased expression of SLC17A7 mRNA CTD PMID:31626844 NCBI chr 1:101,161,265...101,172,292
Ensembl chr 1:101,161,252...101,173,174 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases activity ISO clothianidin results in decreased activity of SLC22A2 protein CTD PMID:31364238 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261 		JBrowse link
G Slc22a6 solute carrier family 22 member 6 decreases activity ISO clothianidin results in decreased activity of SLC22A6 protein CTD PMID:31364238 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 decreases activity ISO clothianidin results in decreased activity of SLC22A8 protein CTD PMID:31364238 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482 		JBrowse link
G Slc28a1 solute carrier family 28 member 1 increases expression ISO clothianidin results in increased expression of SLC28A1 mRNA CTD PMID:31626844 NCBI chr 1:142,948,942...142,992,410
Ensembl chr 1:142,950,540...142,992,615 		JBrowse link
G Slc38a9 solute carrier family 38, member 9 decreases expression ISO clothianidin results in decreased expression of SLC38A9 mRNA CTD PMID:31626844 NCBI chr 2:44,512,556...44,592,793
Ensembl chr 2:44,512,895...44,592,053 		JBrowse link
G Slc45a2 solute carrier family 45, member 2 decreases expression ISO clothianidin results in decreased expression of SLC45A2 mRNA CTD PMID:31626844 NCBI chr 2:60,966,671...60,999,398
Ensembl chr 2:60,966,789...60,999,398 		JBrowse link
G Slc47a2 solute carrier family 47 member 2 decreases activity ISO clothianidin results in decreased activity of SLC47A2 protein CTD PMID:31364238 NCBI chr10:47,587,909...47,631,373
Ensembl chr10:47,588,497...47,630,799 		JBrowse link
G Slc48a1 solute carrier family 48 member 1 increases expression ISO clothianidin results in increased expression of SLC48A1 mRNA CTD PMID:31626844 NCBI chr 7:139,271,698...139,279,499
Ensembl chr 7:139,271,698...139,279,499 		JBrowse link
G Slco1c1 solute carrier organic anion transporter family, member 1c1 increases expression ISO clothianidin results in increased expression of SLCO1C1 mRNA CTD PMID:31626844 NCBI chr 4:175,729,709...175,776,749
Ensembl chr 4:175,729,726...175,776,808 		JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 increases expression ISO clothianidin results in increased expression of SORBS1 mRNA CTD PMID:31626844 NCBI chr 1:259,373,921...259,502,108
Ensembl chr 1:259,376,933...259,484,569 		JBrowse link
G Spata3 spermatogenesis associated 3 increases expression ISO clothianidin results in increased expression of SPATA3 mRNA CTD PMID:31626844 NCBI chr 9:93,029,766...93,042,631
Ensembl chr 9:93,030,714...93,042,631 		JBrowse link
G Spire2 spire-type actin nucleation factor 2 decreases expression ISO clothianidin results in decreased expression of SPIRE2 mRNA CTD PMID:29044138 NCBI chr19:56,136,904...56,175,500
Ensembl chr19:56,136,904...56,175,500 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 increases expression ISO clothianidin results in increased expression of SRD5A2 mRNA CTD PMID:31626844 NCBI chr 6:25,279,635...25,315,501
Ensembl chr 6:25,279,626...25,315,511 		JBrowse link
G Sspo SCO-spondin decreases expression ISO clothianidin results in decreased expression of SSPOP mRNA CTD PMID:29044138 NCBI chr 4:78,076,695...78,133,676
Ensembl chr 4:78,080,310...78,133,654 		JBrowse link
G Stac2 SH3 and cysteine rich domain 2 increases expression ISO clothianidin results in increased expression of STAC2 mRNA CTD PMID:31626844 NCBI chr10:85,988,367...86,004,209
Ensembl chr10:85,988,367...86,004,209 		JBrowse link
G Steap2 STEAP2 metalloreductase increases expression ISO clothianidin results in increased expression of STEAP2 mRNA CTD PMID:31626844 NCBI chr 4:25,506,604...25,527,088
Ensembl chr 4:25,507,463...25,527,087 		JBrowse link
G Susd4 sushi domain containing 4 increases expression ISO clothianidin results in increased expression of SUSD4 mRNA CTD PMID:31626844 NCBI chr13:101,181,932...101,307,912
Ensembl chr13:101,181,994...101,307,908 		JBrowse link
G Sycp2 synaptonemal complex protein 2 decreases expression ISO clothianidin results in decreased expression of SYCP2 mRNA CTD PMID:29044138 NCBI chr 3:173,884,559...173,948,304
Ensembl chr 3:173,884,287...173,947,018 		JBrowse link
G Synpo synaptopodin decreases expression ISO clothianidin results in decreased expression of SYNPO mRNA CTD PMID:29044138 NCBI chr18:55,863,081...55,921,412
Ensembl chr18:55,865,467...55,916,220 		JBrowse link
G Tacr1 tachykinin receptor 1 increases expression ISO clothianidin results in increased expression of TACR1 mRNA CTD PMID:31626844 NCBI chr 4:113,247,236...113,416,139
Ensembl chr 4:113,247,795...113,414,504 		JBrowse link
G Tafa2 TAFA chemokine like family member 2 decreases expression ISO clothianidin results in decreased expression of FAM19A2 mRNA CTD PMID:31626844 NCBI chr 7:66,017,066...66,496,690
Ensembl chr 7:66,017,086...66,172,360 		JBrowse link
G Tafa5 TAFA chemokine like family member 5 increases expression ISO clothianidin results in increased expression of FAM19A5 mRNA CTD PMID:31626844 NCBI chr 7:128,500,009...128,728,834
Ensembl chr 7:128,500,011...128,728,928 		JBrowse link
G Tbx2 T-box transcription factor 2 increases expression ISO clothianidin results in increased expression of TBX2 mRNA CTD PMID:29044138 NCBI chr10:73,278,932...73,290,764
Ensembl chr10:73,279,119...73,289,921 		JBrowse link
G Tcp10b t-complex protein 10b increases expression ISO clothianidin results in increased expression of TCP10L2 mRNA CTD PMID:31626844 NCBI chr 1:53,530,992...53,554,113
Ensembl chr 1:53,531,076...53,554,113 		JBrowse link
G Tecpr1 tectonin beta-propeller repeat containing 1 decreases expression ISO clothianidin results in decreased expression of TECPR1 mRNA CTD PMID:31626844 NCBI chr12:12,374,132...12,403,382
Ensembl chr12:12,374,790...12,402,552 		JBrowse link
G Tef TEF transcription factor, PAR bZIP family member increases expression ISO clothianidin results in increased expression of TEF mRNA CTD PMID:31626844 NCBI chr 7:123,033,971...123,058,606
Ensembl chr 7:123,043,503...123,058,604 		JBrowse link
G Tgfbi transforming growth factor, beta induced increases expression ISO clothianidin results in increased expression of TGFBI mRNA CTD PMID:31626844 NCBI chr17:8,400,123...8,429,338
Ensembl chr17:8,400,146...8,429,338 		JBrowse link
G Tgm5 transglutaminase 5 decreases expression ISO clothianidin results in decreased expression of TGM5 mRNA CTD PMID:29044138 NCBI chr 3:112,995,469...113,033,110
Ensembl chr 3:112,995,568...113,023,532 		JBrowse link
G Tifa TRAF-interacting protein with forkhead-associated domain increases expression ISO clothianidin results in increased expression of TIFA mRNA CTD PMID:31626844 NCBI chr 2:232,104,394...232,137,425
Ensembl chr 2:232,104,809...232,137,422 		JBrowse link
G Tlcd4 TLC domain containing 4 increases expression ISO clothianidin results in increased expression of TLCD4 mRNA CTD PMID:29044138 NCBI chr 2:224,768,034...224,843,198
Ensembl chr 2:224,772,893...224,802,997 		JBrowse link
G Tlx3 T-cell leukemia, homeobox 3 decreases expression ISO clothianidin results in decreased expression of TLX3 mRNA CTD PMID:31626844 NCBI chr10:18,128,869...18,131,745
Ensembl chr10:18,129,408...18,131,562 		JBrowse link
G Tmem273 transmembrane protein 273 increases expression ISO clothianidin results in increased expression of C10ORF128 mRNA CTD PMID:31626844 NCBI chr16:9,023,387...9,054,664
Ensembl chr16:9,023,387...9,054,664 		JBrowse link
G Tmem38a transmembrane protein 38a decreases expression ISO clothianidin results in decreased expression of TMEM38A mRNA CTD PMID:29044138 NCBI chr16:18,960,197...18,974,942
Ensembl chr16:18,959,315...18,974,770 		JBrowse link
G Tmem71 transmembrane protein 71 decreases expression ISO clothianidin results in decreased expression of TMEM71 mRNA CTD PMID:31626844 NCBI chr 7:107,264,235...107,392,808
Ensembl chr 7:107,262,929...107,392,972 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO clothianidin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; clothianidin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:29044138 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B decreases expression ISO clothianidin results in decreased expression of TNFRSF11B mRNA CTD PMID:31626844 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665 		JBrowse link
G Tnxb tenascin XB decreases expression ISO clothianidin results in decreased expression of TNXB mRNA CTD PMID:29044138
G Tpm1 tropomyosin 1 increases expression ISO clothianidin results in increased expression of TPM1 mRNA CTD PMID:29044138 NCBI chr 8:72,814,737...72,841,496
Ensembl chr 8:72,814,740...72,842,228 		JBrowse link
G Traf4 Tnf receptor associated factor 4 increases expression ISO clothianidin results in increased expression of TRAF4 mRNA CTD PMID:29044138 NCBI chr10:65,418,688...65,424,802
Ensembl chr10:65,418,700...65,424,802 		JBrowse link
G Traf6 TNF receptor associated factor 6 decreases expression ISO clothianidin results in decreased expression of TRAF6 mRNA CTD PMID:29044138 NCBI chr 3:91,252,829...91,271,607
Ensembl chr 3:91,252,829...91,271,607 		JBrowse link
G Trappc4 trafficking protein particle complex 4 increases expression ISO clothianidin results in increased expression of TRAPPC4 mRNA CTD PMID:31626844 NCBI chr 8:48,723,755...48,727,182
Ensembl chr 8:48,723,191...48,727,154 		JBrowse link
G Trim37 tripartite motif-containing 37 decreases expression ISO clothianidin results in decreased expression of TRIM37 mRNA CTD PMID:31626844 NCBI chr10:74,436,165...74,568,636
Ensembl chr10:74,436,208...74,568,493 		JBrowse link
G Trmt44 tRNA methyltransferase 44 increases expression ISO clothianidin results in increased expression of TRMT44 mRNA CTD PMID:31626844 NCBI chr14:80,361,490...80,379,408
Ensembl chr14:80,361,294...80,383,138 		JBrowse link
G Tssk6 testis-specific serine kinase 6 decreases expression ISO clothianidin results in decreased expression of TSSK6 mRNA CTD PMID:31626844 NCBI chr16:21,272,282...21,274,756
Ensembl chr16:21,273,387...21,274,688 		JBrowse link
G Ttc28 tetratricopeptide repeat domain 28 decreases expression ISO clothianidin results in decreased expression of TTC28 mRNA CTD PMID:31626844 NCBI chr12:51,385,808...51,840,710
Ensembl chr12:51,385,763...51,702,730 		JBrowse link
G Ttc30b tetratricopeptide repeat domain 30B decreases expression ISO clothianidin results in decreased expression of TTC30B mRNA CTD PMID:31626844 NCBI chr 3:62,758,754...62,761,325
Ensembl chr 3:62,758,758...62,761,325 		JBrowse link
G Ttc33 tetratricopeptide repeat domain 33 decreases expression ISO clothianidin results in decreased expression of TTC33 mRNA CTD PMID:31626844 NCBI chr 2:54,897,320...54,944,241
Ensembl chr 2:54,897,424...54,939,514 		JBrowse link
G Ttc8 tetratricopeptide repeat domain 8 decreases expression ISO clothianidin results in decreased expression of TTC8 mRNA CTD PMID:31626844 NCBI chr 6:122,920,308...122,974,525
Ensembl chr 6:122,920,317...122,974,522 		JBrowse link
G Tubgcp3 tubulin, gamma complex associated protein 3 increases expression ISO clothianidin results in increased expression of TUBGCP3 mRNA CTD PMID:31626844 NCBI chr16:82,184,362...82,245,041
Ensembl chr16:82,184,387...82,245,041 		JBrowse link
G Txndc2 thioredoxin domain containing 2 increases expression ISO clothianidin results in increased expression of TXNDC2 mRNA CTD PMID:31626844 NCBI chr 9:113,354,047...113,358,558
Ensembl chr 9:113,354,053...113,358,526 		JBrowse link
G Ubap1l ubiquitin associated protein 1-like decreases expression
increases expression		 ISO clothianidin results in decreased expression of UBAP1L mRNA
clothianidin results in increased expression of UBAP1L mRNA		 CTD PMID:29044138, PMID:31626844 NCBI chr 8:70,876,516...70,895,723
Ensembl chr 8:70,884,491...70,896,501 		JBrowse link
G Unc119b unc-119 lipid binding chaperone B increases expression ISO clothianidin results in increased expression of UNC119B mRNA CTD PMID:31626844 NCBI chr12:47,239,663...47,252,286
Ensembl chr12:47,218,969...47,252,286 		JBrowse link
G Usp43 ubiquitin specific peptidase 43 decreases expression ISO clothianidin results in decreased expression of USP43 mRNA CTD PMID:31626844 NCBI chr10:54,406,980...54,467,956
Ensembl chr10:54,406,980...54,467,956 		JBrowse link
G Utrn utrophin decreases expression ISO clothianidin results in decreased expression of UTRN mRNA CTD PMID:31626844 NCBI chr 1:6,451,809...6,970,040
Ensembl chr 1:6,451,810...6,970,040 		JBrowse link
G Vamp8 vesicle-associated membrane protein 8 increases expression ISO clothianidin results in increased expression of VAMP8 mRNA CTD PMID:31626844 NCBI chr 4:100,250,301...100,252,756
Ensembl chr 4:100,250,301...100,252,755 		JBrowse link
G Vegfd vascular endothelial growth factor D decreases expression ISO clothianidin results in decreased expression of VEGFD mRNA CTD PMID:31626844 NCBI chr  X:31,816,480...31,852,239
Ensembl chr  X:31,816,436...31,851,715 		JBrowse link
G Vps8 VPS8 subunit of CORVET complex decreases expression ISO clothianidin results in decreased expression of VPS8 mRNA CTD PMID:31626844 NCBI chr11:83,104,912...83,323,606
Ensembl chr11:83,105,064...83,300,409 		JBrowse link
G Washc4 WASH complex subunit 4 increases expression ISO clothianidin results in increased expression of WASHC4 mRNA CTD PMID:31626844 NCBI chr 7:26,309,279...26,361,221
Ensembl chr 7:26,311,094...26,361,221 		JBrowse link
G Whrn whirlin increases expression ISO clothianidin results in increased expression of WHRN mRNA CTD PMID:31626844 NCBI chr 5:79,235,541...79,317,206
Ensembl chr 5:79,234,950...79,317,206 		JBrowse link
G Ypel2 yippee-like 2 increases expression ISO clothianidin results in increased expression of YPEL2 mRNA CTD PMID:31626844 NCBI chr10:74,241,032...74,298,691
Ensembl chr10:74,243,812...74,298,599 		JBrowse link
G Ypel3 yippee-like 3 decreases expression ISO clothianidin results in decreased expression of YPEL3 mRNA CTD PMID:29044138 NCBI chr 1:198,210,525...198,213,821
Ensembl chr 1:198,210,525...198,213,816 		JBrowse link
G Zbtb45 zinc finger and BTB domain containing 45 decreases expression ISO clothianidin results in decreased expression of ZBTB45 mRNA CTD PMID:31626844 NCBI chr 1:65,563,999...65,568,301
Ensembl chr 1:65,564,173...65,568,300 		JBrowse link
G Zcchc13 zinc finger CCHC-type containing 13 decreases expression ISO clothianidin results in decreased expression of ZCCHC13 mRNA CTD PMID:31626844 NCBI chr  X:74,497,127...74,498,269
Ensembl chr  X:74,497,262...74,497,774 		JBrowse link
G Zfp18 zinc finger protein 18 decreases expression ISO clothianidin results in decreased expression of ZNF18 mRNA CTD PMID:31626844 NCBI chr10:52,327,668...52,350,944
Ensembl chr10:52,334,240...52,348,692 		JBrowse link
G Zfp219 zinc finger protein 219 decreases expression ISO clothianidin results in decreased expression of ZNF219 mRNA CTD PMID:29044138 NCBI chr15:28,402,412...28,417,379
Ensembl chr15:28,402,415...28,406,046 		JBrowse link
G Zfp467 zinc finger protein 467 increases expression ISO clothianidin results in increased expression of ZNF467 mRNA CTD PMID:31626844 NCBI chr 4:78,068,822...78,077,962
Ensembl chr 4:78,067,689...78,075,398 		JBrowse link
G Zfp521 zinc finger protein 521 decreases expression ISO clothianidin results in decreased expression of ZNF521 mRNA CTD PMID:31626844 NCBI chr18:5,022,042...5,315,242
Ensembl chr18:5,032,029...5,314,585 		JBrowse link
G Zfp653 zinc finger protein 653 decreases expression ISO clothianidin results in decreased expression of ZNF653 mRNA CTD PMID:31626844 NCBI chr 8:23,066,576...23,085,502
Ensembl chr 8:23,066,576...23,084,879 		JBrowse link
G Zfp865 zinc finger protein 865 increases expression ISO clothianidin results in increased expression of ZNF784 mRNA CTD PMID:31626844 NCBI chr 1:72,356,880...72,361,358
Ensembl chr 1:72,356,880...72,361,358 		JBrowse link
G Zkscan7 zinc finger with KRAB and SCAN domains 7 increases expression ISO clothianidin results in increased expression of ZKSCAN7 mRNA CTD PMID:31626844 NCBI chr 8:131,932,753...131,968,550
Ensembl chr 8:131,933,387...131,950,776 		JBrowse link
G Zswim4 zinc finger, SWIM-type containing 4 decreases expression ISO clothianidin results in decreased expression of ZSWIM4 mRNA CTD PMID:31626844 NCBI chr19:25,320,683...25,345,818
Ensembl chr19:25,320,683...25,345,790 		JBrowse link
dabrafenib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf B-Raf proto-oncogene, serine/threonine kinase multiple interactions
affects response to substance
increases response to substance
decreases activity		 ISO [BRAF protein affects the susceptibility to dabrafenib] which affects the cleavage of SREBF1 protein; betulin affects the reaction [BRAF protein affects the susceptibility to [dabrafenib co-treated with trametinib]]; BRAF protein affects the susceptibility to [dabrafenib co-treated with trametinib]; CCND1 protein inhibits the reaction [BRAF protein mutant form results in increased susceptibility to dabrafenib]; fatostatin affects the reaction [BRAF protein affects the susceptibility to [dabrafenib co-treated with trametinib]]; MAPK1 protein modified form inhibits the reaction [BRAF protein mutant form results in increased susceptibility to dabrafenib]; MAPK3 protein modified form inhibits the reaction [BRAF protein mutant form results in increased susceptibility to dabrafenib]
dabrafenib results in decreased activity of BRAF protein; dabrafenib results in decreased activity of BRAF protein mutant form		 CTD PMID:20823850, PMID:23237741, PMID:26978007, PMID:29950559 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO CCND1 protein inhibits the reaction [BRAF protein mutant form results in increased susceptibility to dabrafenib] CTD PMID:26978007 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO dabrafenib inhibits the reaction [Polyphosphates results in increased expression of GPT protein] CTD PMID:27458080 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO dabrafenib inhibits the reaction [Polyphosphates results in increased expression of ICAM1 mRNA]; dabrafenib inhibits the reaction [Polyphosphates results in increased expression of ICAM1 protein]; dabrafenib inhibits the reaction [TGFBI protein results in increased expression of ICAM1 protein] CTD PMID:27458080, PMID:29042256 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO dabrafenib inhibits the reaction [Polyphosphates results in increased secretion of IL6 protein] CTD PMID:27458080 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Itgav integrin subunit alpha V multiple interactions ISO dabrafenib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of [ITGAV protein binds to ITGB5 protein]] CTD PMID:29042256 NCBI chr 3:71,113,269...71,205,958
Ensembl chr 3:71,114,100...71,202,411 		JBrowse link
G Itgb5 integrin subunit beta 5 multiple interactions ISO dabrafenib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of [ITGAV protein binds to ITGB5 protein]] CTD PMID:29042256 NCBI chr11:70,056,500...70,172,164
Ensembl chr11:70,056,500...70,172,372 		JBrowse link
G Kras KRAS proto-oncogene, GTPase affects response to substance
multiple interactions		 ISO KRAS protein affects the susceptibility to dabrafenib
[KRAS protein affects the susceptibility to dabrafenib] which affects the expression of TNFRSF10B protein; [KRAS protein affects the susceptibility to dabrafenib] which affects the phosphorylation of MAPK1 protein; [KRAS protein affects the susceptibility to dabrafenib] which affects the phosphorylation of MAPK3 protein		 CTD PMID:27222248 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation		 ISO [KRAS protein affects the susceptibility to dabrafenib] which affects the phosphorylation of MAPK1 protein; dabrafenib inhibits the reaction [GSK690693 results in increased phosphorylation of MAPK1 protein]; dabrafenib inhibits the reaction [Polyphosphates results in increased phosphorylation of MAPK1 protein]; MAPK1 protein modified form inhibits the reaction [BRAF protein mutant form results in increased susceptibility to dabrafenib]; SRPIN340 inhibits the reaction [dabrafenib results in increased phosphorylation of MAPK1 protein] CTD PMID:26978007, PMID:27222248, PMID:27458080, PMID:31962201 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 ISO [KRAS protein affects the susceptibility to dabrafenib] which affects the phosphorylation of MAPK3 protein; dabrafenib inhibits the reaction [GSK690693 results in increased phosphorylation of MAPK3 protein]; dabrafenib inhibits the reaction [Polyphosphates results in increased phosphorylation of MAPK3 protein]; MAPK3 protein modified form inhibits the reaction [BRAF protein mutant form results in increased susceptibility to dabrafenib]; SRPIN340 inhibits the reaction [dabrafenib results in increased phosphorylation of MAPK3 protein] CTD PMID:26978007, PMID:27222248, PMID:27458080, PMID:31962201 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO dabrafenib inhibits the reaction [Polyphosphates results in increased activity of RELA protein] CTD PMID:27458080 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249 		JBrowse link
G Sele selectin E multiple interactions ISO dabrafenib inhibits the reaction [Polyphosphates results in increased expression of SELE mRNA]; dabrafenib inhibits the reaction [Polyphosphates results in increased expression of SELE protein]; dabrafenib inhibits the reaction [TGFBI protein results in increased expression of SELE protein] CTD PMID:27458080, PMID:29042256 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases cleavage
multiple interactions		 ISO dabrafenib results in decreased cleavage of SREBF1 protein
[BRAF protein affects the susceptibility to dabrafenib] which affects the cleavage of SREBF1 protein		 CTD PMID:29950559 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009 		JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 multiple interactions ISO [SRPIN340 co-treated with dabrafenib] results in decreased phosphorylation of SRSF5 protein CTD PMID:31962201 NCBI chr 6:104,611,026...104,640,033
Ensembl chr 6:104,611,026...104,615,302 		JBrowse link
G Tgfbi transforming growth factor, beta induced multiple interactions ISO dabrafenib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TGFBI mRNA]; dabrafenib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TGFBI protein]; dabrafenib inhibits the reaction [TGFBI protein results in increased expression of ICAM1 protein]; dabrafenib inhibits the reaction [TGFBI protein results in increased expression of SELE protein]; dabrafenib inhibits the reaction [TGFBI protein results in increased expression of VCAM1 protein] CTD PMID:29042256 NCBI chr17:8,400,123...8,429,338
Ensembl chr17:8,400,146...8,429,338 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO dabrafenib inhibits the reaction [Polyphosphates results in increased expression of TNF protein] CTD PMID:27458080 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO dabrafenib inhibits the reaction [Polyphosphates results in increased expression of VCAM1 mRNA]; dabrafenib inhibits the reaction [Polyphosphates results in increased expression of VCAM1 protein]; dabrafenib inhibits the reaction [TGFBI protein results in increased expression of VCAM1 protein] CTD PMID:27458080, PMID:29042256 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619 		JBrowse link
epothilone A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases expression
multiple interactions		 ISO epothilone A results in increased expression of CASP3 mRNA
[epothilone A co-treated with Metformin] results in increased expression of CASP3 mRNA; Sodium Salicylate promotes the reaction [[epothilone A co-treated with Metformin] results in increased expression of CASP3 mRNA]; triciribine promotes the reaction [[epothilone A co-treated with Metformin] results in increased expression of CASP3 mRNA]		 CTD PMID:29117515 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases expression		 ISO [epothilone A co-treated with Metformin] results in increased expression of H2AX mRNA
epothilone A results in increased expression of H2AX mRNA		 CTD PMID:29117515 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases expression		 ISO [epothilone A co-treated with Metformin] results in increased expression of PARP1 mRNA; Sodium Salicylate inhibits the reaction [epothilone A results in increased expression of PARP1 mRNA]; triciribine inhibits the reaction [epothilone A results in increased expression of PARP1 mRNA]; triciribine promotes the reaction [[epothilone A co-treated with Metformin] results in increased expression of PARP1 mRNA] CTD PMID:29117515 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
epothilone B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha decreases expression
multiple interactions		 EXP epothilone B results in decreased expression of CALCA protein
epothilone B affects the reaction [[Capsaicin co-treated with NGF protein] results in increased secretion of CALCA protein]; epothilone B inhibits the reaction [Potassium results in increased secretion of CALCA protein]; epothilone B promotes the reaction [[Potassium co-treated with NGF protein] results in increased secretion of CALCA protein]		 CTD PMID:26883566 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911 		JBrowse link
G Ngf nerve growth factor multiple interactions EXP epothilone B affects the reaction [[Capsaicin co-treated with NGF protein] results in increased secretion of CALCA protein]; epothilone B promotes the reaction [[Potassium co-treated with NGF protein] results in increased secretion of CALCA protein] CTD PMID:26883566 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453 		JBrowse link
famotidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 multiple interactions ISO Famotidine inhibits the reaction [ADCYAP1 protein affects the secretion of Acids] CTD PMID:20388963 NCBI chr 9:121,705,897...121,725,736
Ensembl chr 9:121,706,979...121,725,716 		JBrowse link
G Agt angiotensinogen multiple interactions EXP Famotidine inhibits the reaction [Indomethacin results in increased expression of AGT protein] CTD PMID:27645307 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase decreases activity ISO Famotidine results in decreased activity of BRAF protein CTD PMID:20823850 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356 		JBrowse link
G Ca12 carbonic anhydrase 12 multiple interactions ISO Famotidine binds to and results in decreased activity of CA12 protein CTD PMID:30344913 NCBI chr 8:72,405,770...72,461,425
Ensembl chr 8:72,405,748...72,460,240 		JBrowse link
G Ca6 carbonic anhydrase 6 multiple interactions ISO Famotidine binds to and results in decreased activity of CA6 protein CTD PMID:30344913 NCBI chr 5:167,226,246...167,244,786
Ensembl chr 5:167,226,246...167,244,786 		JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions ISO Famotidine binds to and results in decreased activity of CA2 protein CTD PMID:30344913 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029 		JBrowse link
G Car7 carbonic anhydrase 7 multiple interactions ISO Famotidine binds to and results in decreased activity of CA7 protein CTD PMID:30344913 NCBI chr19:636,545...645,935
Ensembl chr19:636,545...645,937 		JBrowse link
G Cat catalase multiple interactions EXP Famotidine inhibits the reaction [Indomethacin results in decreased activity of CAT protein]; Famotidine inhibits the reaction [Indomethacin results in increased activity of CAT protein]; Quercetin promotes the reaction [Famotidine inhibits the reaction [Indomethacin results in decreased activity of CAT protein]] CTD PMID:18726076, PMID:19034656, PMID:19497431, PMID:25926722 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO Famotidine inhibits the reaction [Histamine inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein]] CTD PMID:12538815 NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
increases expression		 ISO Famotidine inhibits the reaction [Dizocilpine Maleate results in decreased expression of CTNNB1 mRNA]
Famotidine results in increased expression of CTNNB1 mRNA		 CTD PMID:31563592 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression EXP Famotidine results in increased expression of CXCL1 protein CTD PMID:12023551 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457 		JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 multiple interactions ISO Famotidine inhibits the reaction [CYP2C19 gene affects the susceptibility to Lansoprazole] CTD PMID:15963082 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007 		JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions ISO [Famotidine co-treated with Sucralfate] results in increased expression of FGF2 mRNA CTD PMID:17717918 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681 		JBrowse link
G Fgf21 fibroblast growth factor 21 increases expression ISO Famotidine results in increased expression of FGF21 protein CTD PMID:8774986 NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Famotidine inhibits the reaction [[Dimaprit binds to and results in increased activity of HRH2 protein] which results in increased expression of FOS mRNA]; Famotidine inhibits the reaction [[Histamine binds to and results in increased activity of HRH2 protein] which results in increased expression of FOS mRNA] CTD PMID:9187264 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299 		JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions EXP Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein]] CTD PMID:15363660 NCBI chr10:27,310,718...27,371,802
Ensembl chr10:27,310,725...27,366,665 		JBrowse link
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 multiple interactions EXP Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15363660 NCBI chr  X:152,414,332...152,642,607
Ensembl chr  X:152,414,615...152,642,531 		JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions EXP Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15363660 NCBI chr10:27,973,694...28,193,072
Ensembl chr10:27,973,681...28,187,565 		JBrowse link
G Gabrg1 gamma-aminobutyric acid type A receptor subunit gamma 1 multiple interactions EXP Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG1 protein]] CTD PMID:15363660 NCBI chr14:39,964,502...40,051,306
Ensembl chr14:39,964,588...40,049,354 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions EXP Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15363660 NCBI chr10:27,090,913...27,179,786
Ensembl chr10:27,092,827...27,179,900 		JBrowse link
G Gast gastrin affects expression
increases expression		 ISO
EXP		 Famotidine affects the expression of GAST protein
Famotidine results in increased expression of GAST protein		 CTD PMID:12503773, PMID:17652263 NCBI chr10:88,245,532...88,248,485
Ensembl chr10:88,245,532...88,248,484 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide multiple interactions EXP Famotidine inhibits the reaction [GHRL protein results in increased secretion of Acids] CTD PMID:16838121 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO Famotidine inhibits the reaction [Dizocilpine Maleate results in decreased phosphorylation of and results in increased activity of GSK3B protein]; Famotidine inhibits the reaction [Dizocilpine Maleate results in increased expression of GSK3B mRNA] CTD PMID:31563592 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268 		JBrowse link
G Hrh2 histamine receptor H 2 multiple interactions
decreases activity
increases expression		 ISO
EXP		 [Famotidine binds to and results in decreased activity of HRH2 protein] which affects the susceptibility to Metformin; Famotidine binds to and results in decreased activity of HRH2 protein; Famotidine inhibits the reaction [[Dimaprit binds to and results in increased activity of HRH2 protein] which results in increased expression of FOS mRNA]; Famotidine inhibits the reaction [[Histamine binds to and results in increased activity of HRH2 protein] which results in increased expression of FOS mRNA]
Famotidine results in decreased activity of HRH2 protein
[Famotidine binds to and results in decreased activity of HRH2 protein] which affects the susceptibility to Histamine
Famotidine results in increased expression of HRH2 protein		 CTD PMID:9187264, PMID:9681472, PMID:12832840, PMID:15961859, PMID:16632449, PMID:21276809 NCBI chr17:10,912,959...10,931,389
Ensembl chr17:10,921,507...10,952,441 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression
multiple interactions		 EXP Famotidine results in decreased expression of HSPA1A protein
Zinc Compounds analog inhibits the reaction [Famotidine results in decreased expression of HSPA1A protein]; Zinc Sulfate inhibits the reaction [Famotidine results in decreased expression of HSPA1A protein]		 CTD PMID:16945336 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of ICAM1 protein]]; Famotidine inhibits the reaction [Histamine inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]] CTD PMID:11752121, PMID:12364868, PMID:12538815 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Ifng interferon gamma multiple interactions ISO Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of IFNG protein]]
Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]]		 CTD PMID:11752121, PMID:12364868, PMID:19277450 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in decreased expression of IL10 protein]] CTD PMID:11752121 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Il12a interleukin 12A multiple interactions ISO Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]] CTD PMID:11752121, PMID:12364868 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]] CTD PMID:11752121, PMID:12364868 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085 		JBrowse link
G Il18 interleukin 18 multiple interactions ISO Famotidine inhibits the reaction [Cimetidine results in increased expression of IL18 protein]; Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in decreased expression of IL10 protein]]; Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]]; Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of ICAM1 protein]]; Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of IFNG protein]]; Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of TNF protein]] CTD PMID:11752121, PMID:12364868, PMID:16723495 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP		 [Famotidine co-treated with Sucralfate] results in decreased expression of IL1B mRNA
Famotidine inhibits the reaction [Ethanol results in increased expression of IL1B protein]; Famotidine inhibits the reaction [Indomethacin results in increased expression of IL1B mRNA]		 CTD PMID:17717918, PMID:27474069, PMID:27645307 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]] CTD PMID:19277450 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]] CTD PMID:19277450 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP Famotidine inhibits the reaction [Ethanol results in increased expression of IL6 protein]; Famotidine inhibits the reaction [Ethanol results in increased secretion of IL6 protein] CTD PMID:17603938, PMID:27474069 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Famotidine inhibits the reaction [Histamine results in increased phosphorylation of MAPK1 protein] CTD PMID:17656145 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Famotidine inhibits the reaction [Histamine results in increased phosphorylation of MAPK3 protein] CTD PMID:17656145 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO Famotidine inhibits the reaction [Histamine results in increased expression of MMP1 mRNA]; Famotidine inhibits the reaction [Histamine results in increased secretion of MMP1 protein] CTD PMID:17656145 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP Famotidine inhibits the reaction [Ethanol results in increased expression of and results in increased activity of MMP9 protein]; Famotidine inhibits the reaction [Ethanol results in increased expression of MMP9 mRNA]; Famotidine inhibits the reaction [Ethanol results in increased secretion of and results in increased activity of MMP9 protein]; Famotidine inhibits the reaction [Ethanol results in increased secretion of MMP9 protein] CTD PMID:17603938, PMID:22257724 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520 		JBrowse link
G Mpo myeloperoxidase multiple interactions
increases expression		 ISO
EXP		 Famotidine inhibits the reaction [Acids results in increased activity of MPO protein]
Famotidine results in increased expression of MPO protein
Famotidine inhibits the reaction [Ethanol results in increased activity of MPO protein]; Famotidine inhibits the reaction [Indomethacin results in increased activity of MPO protein]; Famotidine promotes the reaction [Chlorpheniramine results in decreased activity of MPO protein]; Quercetin promotes the reaction [Famotidine inhibits the reaction [Indomethacin results in increased activity of MPO protein]]		 CTD PMID:12023551, PMID:16091555, PMID:16437673, PMID:17603938, PMID:18726076, PMID:19034656, PMID:19497431, PMID:20723003, PMID:22257724, PMID:25926722, PMID:27474069 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260 		JBrowse link
G Nppb natriuretic peptide B decreases expression EXP Famotidine results in decreased expression of NPPB protein CTD PMID:30310171 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531 		JBrowse link
G Ntf3 neurotrophin 3 multiple interactions EXP [Pyrilamine co-treated with Famotidine co-treated with ciproxifan] inhibits the reaction [Histamine results in increased expression of NTF3 protein]; [Pyrilamine co-treated with Famotidine] inhibits the reaction [Histamine results in increased expression of NTF3 protein]; Famotidine inhibits the reaction [Histamine results in increased expression of NTF3 protein] CTD PMID:21276809 NCBI chr 4:158,636,883...158,705,886
Ensembl chr 4:158,636,884...158,705,886 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [Famotidine co-treated with Indomethacin] promotes the reaction [Acetic Acid results in increased expression of PCNA protein]; Famotidine promotes the reaction [Acetic Acid results in increased expression of PCNA protein] CTD PMID:18853145, PMID:19251492 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha decreases expression EXP Famotidine results in decreased expression of PPP3CA protein CTD PMID:30310171 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854 		JBrowse link
G Prdx3 peroxiredoxin 3 increases expression EXP Famotidine results in increased expression of PRDX3 protein CTD PMID:30310171 NCBI chr 1:282,238,774...282,251,193
Ensembl chr 1:282,238,773...282,251,257 		JBrowse link
G Prl prolactin increases expression ISO Famotidine results in increased expression of PRL protein CTD PMID:8104296 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP Famotidine inhibits the reaction [Indomethacin results in increased expression of PTGS1 mRNA] CTD PMID:27645307 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP Famotidine inhibits the reaction [Indomethacin results in increased expression of PTGS2 mRNA] CTD PMID:27645307 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Famotidine inhibits the reaction [Ethanol results in increased expression of RELA protein] CTD PMID:27474069 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249 		JBrowse link
G RT1-DMb RT1 class II, locus DMb affects expression ISO Famotidine affects the expression of HLA-DMB mRNA CTD PMID:25811541 NCBI chr20:3,945,383...3,952,838
Ensembl chr20:5,227,045...5,234,290 		JBrowse link
G RT1-S3 RT1 class Ib, locus S3 affects expression ISO Famotidine affects the expression of HLA-E mRNA CTD PMID:25811541 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions EXP Heparin promotes the reaction [[Famotidine co-treated with Lipopolysaccharides] results in increased expression of SERPINE1 protein] CTD PMID:16401727 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482 		JBrowse link
G Slc19a3 solute carrier family 19 member 3 multiple interactions
increases uptake		 ISO Famotidine inhibits the reaction [SLC19A3 protein results in increased uptake of Metformin]; Famotidine inhibits the reaction [SLC19A3 protein results in increased uptake of Thiamine]
SLC19A3 protein results in increased uptake of Famotidine		 CTD PMID:26528626 NCBI chr 9:88,762,775...88,828,553
Ensembl chr 9:88,764,073...88,816,898 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions
increases uptake
affects transport		 ISO
EXP		 Famotidine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]
SLC22A1 protein results in increased uptake of Famotidine
SLC22A1 protein affects the transport of Famotidine		 CTD PMID:16006492, PMID:16141367 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 increases uptake
multiple interactions		 ISO
EXP		 SLC22A2 protein results in increased uptake of Famotidine
Famotidine inhibits the reaction [SLC22A2 protein affects the transport of Tetraethylammonium]; Famotidine inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]; Famotidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]		 CTD PMID:15496291, PMID:16006492, PMID:16141367, PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions
decreases activity		 ISO Famotidine inhibits the reaction [SLC22A3 protein affects the transport of 1-Methyl-4-phenylpyridinium]; Famotidine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]
Famotidine results in decreased activity of SLC22A3 protein		 CTD PMID:16141367 NCBI chr 1:48,433,079...48,521,261
Ensembl chr 1:48,433,079...48,521,256 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions
increases uptake		 ISO
EXP		 estrone sulfate inhibits the reaction [SLC22A8 protein results in increased uptake of Famotidine]; Famotidine inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate]; Probenecid inhibits the reaction [SLC22A8 protein affects the transport of Famotidine]
Famotidine inhibits the reaction [SLC22A8 protein results in increased uptake of Cimetidine]; Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of Famotidine]; Probenecid inhibits the reaction [SLC22A8 protein affects the transport of Famotidine]; Probenecid promotes the reaction [SLC22A8 protein results in increased uptake of Famotidine]
Famotidine inhibits the reaction [SLC22A8 protein results in increased uptake of p-Aminohippuric Acid]		 CTD PMID:15100168, PMID:15319347, PMID:15496291, PMID:16006492 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482 		JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Famotidine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:47,631,425...47,685,379
Ensembl chr10:47,632,192...47,666,921 		JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Famotidine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:47,587,909...47,631,373
Ensembl chr10:47,588,497...47,630,799 		JBrowse link
G Tacr1 tachykinin receptor 1 multiple interactions ISO Famotidine inhibits the reaction [Acids affects the localization of TACR1 protein] CTD PMID:16091555 NCBI chr 4:113,247,236...113,416,139
Ensembl chr 4:113,247,795...113,414,504 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases secretion		 ISO
EXP		 Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of TNF protein]]; Famotidine inhibits the reaction [Histamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]
Famotidine results in increased secretion of TNF protein
Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]]
Famotidine inhibits the reaction [Ethanol results in increased expression of TNF protein]; Famotidine inhibits the reaction [Ethanol results in increased secretion of TNF protein]; Famotidine inhibits the reaction [Indomethacin results in increased expression of TNF mRNA]		 CTD PMID:11752121, PMID:12538815, PMID:17603938, PMID:17698507, PMID:19277450, PMID:27474069, PMID:27645307 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
febuxostat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP Febuxostat inhibits the reaction [Doxorubicin results in increased expression of BAX protein] CTD PMID:26036690 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP Febuxostat inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein] CTD PMID:26036690 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP Febuxostat inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein] CTD PMID:26036690 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Febuxostat results in increased expression of CCL2 mRNA CTD PMID:26641773 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 multiple interactions ISO Febuxostat inhibits the reaction [[myelin oligodendrocyte glycoprotein (35-55) co-treated with Freund's Adjuvant] results in decreased expression of GOT2 mRNA]; Febuxostat inhibits the reaction [[myelin oligodendrocyte glycoprotein (35-55) co-treated with Freund's Adjuvant] results in decreased expression of GOT2 protein] CTD PMID:29107957 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions EXP Febuxostat inhibits the reaction [Doxorubicin results in increased expression of IKBKB protein] CTD PMID:26036690 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815 		JBrowse link
G Nppb natriuretic peptide B multiple interactions EXP Febuxostat inhibits the reaction [Doxorubicin results in increased expression of NPPB protein] CTD PMID:26036690 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Febuxostat inhibits the reaction [Doxorubicin results in increased expression of RELA protein] CTD PMID:26036690 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP Febuxostat inhibits the reaction [Doxorubicin results in decreased expression of SOD2 protein] CTD PMID:26036690 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 EXP
ISO		 Febuxostat inhibits the reaction [Doxorubicin results in increased expression of TNF protein]
Febuxostat results in increased expression of TNF mRNA		 CTD PMID:26036690, PMID:26641773 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
fluensulfone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 increases response to substance
increases metabolic processing		 ISO CYP2F2 protein results in increased susceptibility to fluensulfone
CYP2F2 protein results in increased metabolism of fluensulfone		 CTD PMID:27605420 NCBI chr 1:83,933,974...83,947,804
Ensembl chr 1:83,933,942...83,947,821 		JBrowse link
GW 501516 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO GW 501516 results in increased expression of ABCA1 mRNA; GW 501516 results in increased expression of ABCA1 protein CTD PMID:19201410 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015 		JBrowse link
G Abhd3 abhydrolase domain containing 3, phospholipase multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of ABHD3 mRNA CTD PMID:16197558 NCBI chr18:1,892,413...1,946,840
Ensembl chr18:1,892,413...1,946,840 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of ACADM mRNA CTD PMID:16197558 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589 		JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of ACADVL mRNA CTD PMID:16197558 NCBI chr10:56,619,321...56,624,468
Ensembl chr10:56,619,303...56,624,526 		JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression ISO GW 501516 results in increased expression of ACOX1 mRNA CTD PMID:16574099 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050 		JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of ANGPTL4 mRNA CTD PMID:16197558 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079 		JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO GW 501516 promotes the reaction [APOA1 protein results in increased secretion of Lipids] CTD PMID:19201410 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875 		JBrowse link
G App amyloid beta precursor protein multiple interactions ISO GW 501516 inhibits the reaction [APP gene mutant form results in decreased expression of GCH1 protein]; GW 501516 inhibits the reaction [APP gene mutant form results in decreased expression of SOD1 protein]; GW 501516 inhibits the reaction [APP gene mutant form results in decreased expression of SOD3 protein]; GW 501516 inhibits the reaction [APP gene mutant form results in decreased phosphorylation of NOS3 protein]; GW 501516 inhibits the reaction [APP gene mutant form results in decreased susceptibility to Acetylcholine]; GW 501516 inhibits the reaction [APP gene mutant form results in increased abundance of 7,8-dihydrobiopterin]; GW 501516 inhibits the reaction [APP gene mutant form results in increased chemical synthesis of Superoxides]; GW 501516 inhibits the reaction [APP gene mutant form results in increased expression of CYBB protein]; GW 501516 inhibits the reaction [APP gene mutant form results in increased oxidation of and results in decreased abundance of sapropterin] CTD PMID:22886847 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Bcl6 BCL6, transcription repressor multiple interactions ISO BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]]; BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]]; BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]]; BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of MMP9 protein]]; BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of SELE mRNA]]; BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]] CTD PMID:23737761 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases expression		 ISO BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; GW 501516 inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]
GW 501516 results in decreased expression of CCL2 mRNA
GW 501516 inhibits the reaction [Palmitates results in increased expression of CCL2 mRNA]; GW 501516 inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]		 CTD PMID:16574099, PMID:21966476, PMID:23737761 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of CEBPA mRNA CTD PMID:16197558 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions
increases expression		 ISO [GW 501516 binds to PPARD protein] which results in increased expression of CPT1A mRNA
GW 501516 results in increased expression of CPT1A mRNA		 CTD PMID:16197558, PMID:16574099 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678 		JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B multiple interactions
increases expression		 EXP RELA protein inhibits the reaction [GW 501516 results in increased expression of CPT1B mRNA] CTD PMID:18701451 NCBI chr 7:130,395,211...130,404,731
Ensembl chr 7:130,395,194...130,405,347 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 decreases expression ISO GW 501516 results in decreased expression of CX3CR1 mRNA CTD PMID:19850645 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514 		JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions ISO GW 501516 inhibits the reaction [APP gene mutant form results in increased expression of CYBB protein] CTD PMID:22886847 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 multiple interactions ISO GW 501516 inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA] CTD PMID:19667161 NCBI chr 3:168,097,484...168,111,920
Ensembl chr 3:168,097,485...168,111,920 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of DDIT4 mRNA CTD PMID:16197558 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382 		JBrowse link
G Ech1 enoyl-CoA hydratase 1 multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of ECH1 mRNA CTD PMID:16197558 NCBI chr 1:87,009,798...87,015,996
Ensembl chr 1:87,009,730...87,016,005 		JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression
multiple interactions		 ISO GW 501516 results in increased expression of FABP1 mRNA
[GW 501516 binds to PPARD protein] which results in increased expression of FABP1 mRNA		 CTD PMID:16197558, PMID:16574099 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954 		JBrowse link
G Gch1 GTP cyclohydrolase 1 multiple interactions ISO GW 501516 inhibits the reaction [APP gene mutant form results in decreased expression of GCH1 protein] CTD PMID:22886847 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of HADHA mRNA CTD PMID:16197558 NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of HMGCS2 mRNA CTD PMID:16197558 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423 		JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of HSDL2 mRNA CTD PMID:16197558 NCBI chr 5:76,812,881...76,848,853
Ensembl chr 5:76,812,931...76,848,101 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]]; GW 501516 inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] CTD PMID:23737761 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression		 ISO BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]]; GW 501516 inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]
GW 501516 results in decreased expression of IL1B mRNA		 CTD PMID:16574099, PMID:23737761 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il6 interleukin 6 decreases expression ISO GW 501516 results in decreased expression of IL6 mRNA CTD PMID:16574099 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Kiz kizuna centrosomal protein multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of KIZ mRNA CTD PMID:16197558 NCBI chr 3:141,067,981...141,173,738
Ensembl chr 3:141,068,023...141,173,858 		JBrowse link
G Lipc lipase C, hepatic type multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of LIPC mRNA CTD PMID:16197558 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248 		JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions EXP MDM2 protein inhibits the reaction [GW 501516 results in increased activity of PPARB protein] CTD PMID:19103650 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]]; BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of MMP9 protein]]; GW 501516 inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; GW 501516 inhibits the reaction [TNF protein results in increased expression of MMP9 protein]; PPARD mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of MMP9 protein]] CTD PMID:23737761 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520 		JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of NEDD9 mRNA CTD PMID:16197558 NCBI chr17:22,984,792...23,179,701
Ensembl chr17:22,984,844...23,179,701 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity ISO GW 501516 results in increased activity of NFE2L2 protein CTD PMID:30114225 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression ISO GW 501516 results in decreased expression of NFKB1 mRNA CTD PMID:16574099 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO GW 501516 inhibits the reaction [APP gene mutant form results in decreased phosphorylation of NOS3 protein] CTD PMID:22886847 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410 		JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP [GW 501516 binds to PPARD protein] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA] CTD PMID:18701451 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705 		JBrowse link
G Nppb natriuretic peptide B multiple interactions EXP [GW 501516 binds to PPARD protein] inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA] CTD PMID:18701451 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 increases expression ISO GW 501516 results in increased expression of NR1H2 mRNA CTD PMID:19201410 NCBI chr 1:100,554,577...100,559,896
Ensembl chr 1:100,554,544...100,559,942 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 increases expression
affects response to substance
multiple interactions		 ISO GW 501516 results in increased expression of NR1H3 mRNA
NR1H3 protein affects the susceptibility to GW 501516
NR1H3 protein affects the reaction [GW 501516 results in increased expression of PPARA mRNA]		 CTD PMID:19201410 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO GW 501516 promotes the reaction [Indomethacin results in increased cleavage of PARP1 protein] CTD PMID:21400612 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of PCK1 mRNA CTD PMID:16197558 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871 		JBrowse link
G Pdzk1 PDZ domain containing 1 multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of PDZK1 mRNA CTD PMID:16197558 NCBI chr 2:198,965,685...198,999,323
Ensembl chr 2:198,965,685...198,999,323 		JBrowse link
G Plin2 perilipin 2 multiple interactions
increases expression		 ISO [GW 501516 binds to PPARD protein] which results in increased expression of PLIN2 mRNA; PPARD mutant form inhibits the reaction [GW 501516 results in increased expression of PLIN2 mRNA] CTD PMID:16197558, PMID:23737761 NCBI chr 5:104,984,413...105,010,863
Ensembl chr 5:104,984,414...105,010,857 		JBrowse link
G Pltp phospholipid transfer protein multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of PLTP mRNA CTD PMID:16197558 NCBI chr 3:161,304,469...161,322,289
Ensembl chr 3:161,304,469...161,322,289 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
affects response to substance
increases expression
affects binding		 ISO [Calcitriol co-treated with GW 501516] results in increased expression of PPARA mRNA; NR1H3 protein affects the reaction [GW 501516 results in increased expression of PPARA mRNA]
PPARA protein affects the susceptibility to GW 501516
GW 501516 binds to PPARA protein		 CTD PMID:19201410, PMID:19667161, PMID:23843199, PMID:25689681 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects binding
increases expression
multiple interactions
increases activity		 ISO
EXP		 GW 501516 binds to PPARB protein; GW 501516 binds to PPARD protein
GW 501516 results in increased expression of PPARD mRNA
4-chloro-N-(2-((5-trifluoromethyl-2-pyridyl)sulfonyl)ethyl)benzamide inhibits the reaction [GW 501516 results in increased expression of PPARD mRNA]; [GW 501516 co-treated with PPARD protein] results in increased expression of PPARGC1A mRNA; GW 501516 binds to and results in increased activity of PPARD protein
GW 501516 results in increased activity of PPARD protein
[GW 501516 binds to PPARD protein] inhibits the reaction [Phenylephrine results in increased activity of RELA protein]; [GW 501516 binds to PPARD protein] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; [GW 501516 binds to PPARD protein] inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA]; MDM2 protein inhibits the reaction [GW 501516 results in increased activity of PPARB protein]
[Calcitriol co-treated with GW 501516] results in increased expression of PPARD mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of ABHD3 mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of ACADM mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of ACADVL mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of ANGPTL4 mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of CEBPA mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of CPT1A mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of DDIT4 mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of ECH1 mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of FABP1 mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of HADHA mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of HMGCS2 mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of HSDL2 mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of KIZ mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of LIPC mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of NEDD9 mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of PCK1 mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of PDZK1 mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of PLIN2 mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of PLTP mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of RNU7-65P mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of SERPINE1 mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of SLC22A7 mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of SLC30A10 mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of SULT2A1 mRNA; [GW 501516 binds to PPARD protein] which results in increased expression of TRIB2 mRNA; GW 501516 binds to and results in increased activity of PPARD protein; GW 501516 promotes the reaction [PPARD protein results in increased expression of SIRT1 mRNA]; PPARD mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of MMP9 protein]]; PPARD mutant form inhibits the reaction [GW 501516 results in increased expression of PLIN2 mRNA]		 CTD PMID:16197558, PMID:17275789, PMID:18292206, PMID:18701451, PMID:19103650, PMID:19201410, PMID:19667161, PMID:20160399, PMID:20516370, PMID:21966476, PMID:23391484, PMID:23737761, PMID:23843199, PMID:27551952, PMID:32407875 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
increases activity		 ISO GW 501516 results in increased expression of PPARG mRNA
GW 501516 results in increased activity of PPARG protein		 CTD PMID:16386710, PMID:19201410 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions
increases expression		 ISO [GW 501516 co-treated with PPARD protein] results in increased expression of PPARGC1A mRNA
GW 501516 results in increased expression of PPARGC1A mRNA		 CTD PMID:17275789, PMID:23056435 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression		 ISO cannabidiolic acid inhibits the reaction [GW 501516 results in increased expression of PTGS2 mRNA] CTD PMID:32238697 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP [GW 501516 binds to PPARD protein] inhibits the reaction [Phenylephrine results in increased activity of RELA protein]; RELA protein inhibits the reaction [GW 501516 results in increased expression of CPT1B mRNA] CTD PMID:18701451 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249 		JBrowse link
G Sele selectin E multiple interactions ISO BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of SELE mRNA]]; GW 501516 inhibits the reaction [TNF protein results in increased expression of SELE mRNA] CTD PMID:23737761 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of SERPINE1 mRNA CTD PMID:16197558 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO GW 501516 promotes the reaction [PPARD protein results in increased expression of SIRT1 mRNA] CTD PMID:20160399 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199 		JBrowse link
G Slc22a7 solute carrier family 22 member 7 multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of SLC22A7 mRNA CTD PMID:16197558 NCBI chr 9:16,925,321...16,931,119
Ensembl chr 9:16,924,520...16,931,766 		JBrowse link
G Slc30a10 solute carrier family 30, member 10 multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of SLC30A10 mRNA CTD PMID:16197558 NCBI chr13:103,396,295...103,406,759
Ensembl chr13:103,396,314...103,410,363 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO GW 501516 inhibits the reaction [APP gene mutant form results in decreased expression of SOD1 protein] CTD PMID:22886847 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862 		JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions ISO GW 501516 inhibits the reaction [APP gene mutant form results in decreased expression of SOD3 protein] CTD PMID:22886847 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B decreases activity ISO GW 501516 results in decreased activity of STAT5B protein CTD PMID:30114225 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of SULT2A1 mRNA CTD PMID:16197558 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression ISO GW 501516 results in decreased expression of TGFB1 mRNA CTD PMID:16574099 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression		 ISO BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]]; BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]]; BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]]; BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of MMP9 protein]]; BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of SELE mRNA]]; BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]]; GW 501516 inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; GW 501516 inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; GW 501516 inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]; GW 501516 inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; GW 501516 inhibits the reaction [TNF protein results in increased expression of MMP9 protein]; GW 501516 inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; GW 501516 inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; PPARD mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of MMP9 protein]]
GW 501516 results in decreased expression of TNF mRNA		 CTD PMID:16574099, PMID:21966476, PMID:23737761 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Trib2 tribbles pseudokinase 2 multiple interactions ISO [GW 501516 binds to PPARD protein] which results in increased expression of TRIB2 mRNA CTD PMID:16197558 NCBI chr 6:41,016,722...41,040,972
Ensembl chr 6:41,016,730...41,039,437 		JBrowse link
G Ucp2 uncoupling protein 2 increases expression EXP GW 501516 results in increased expression of UCP2 mRNA CTD PMID:16239165 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO BCL6 mutant form inhibits the reaction [GW 501516 inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]]; GW 501516 inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA] CTD PMID:23737761 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619 		JBrowse link
G Vdr vitamin D receptor increases expression
multiple interactions		 ISO GW 501516 results in increased expression of VDR mRNA
[Calcitriol co-treated with GW 501516] results in increased expression of VDR mRNA		 CTD PMID:19667161 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166 		JBrowse link
meloxicam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO Meloxicam inhibits the reaction [Doxorubicin results in increased activity of ABCB1 protein]; Meloxicam inhibits the reaction [Doxorubicin results in increased expression of ABCB1 protein] CTD PMID:15501994 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 affects binding ISO ABCC4 protein binds to meloxicam CTD PMID:17939016 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592 		JBrowse link
G App amyloid beta precursor protein multiple interactions ISO meloxicam inhibits the reaction [Aluminum results in increased expression of APP protein] CTD PMID:16928369 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO meloxicam results in increased expression of BAX protein CTD PMID:19709125 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bdkrb1 bradykinin receptor B1 multiple interactions EXP meloxicam inhibits the reaction [KNG1 protein binds to and results in increased activity of BDKRB1 protein] CTD PMID:11159707 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions		 ISO
EXP		 meloxicam results in increased activity of CASP3 protein
Meloxicam inhibits the reaction [Diquat results in increased expression of CASP3 protein modified form]
[Rutin co-treated with Meloxicam] affects the reaction [Formaldehyde affects the expression of CASP3 protein]; Meloxicam affects the reaction [Formaldehyde affects the expression of CASP3 protein]; Meloxicam inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]		 CTD PMID:19709125, PMID:24799355, PMID:29315975, PMID:29484840 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp9 caspase 9 multiple interactions EXP Meloxicam inhibits the reaction [Diquat results in increased expression of CASP9 protein modified form] CTD PMID:29484840 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778 		JBrowse link
G Cat catalase multiple interactions ISO meloxicam inhibits the reaction [Doxorubicin results in decreased activity of CAT protein] CTD PMID:24799355 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Chat choline O-acetyltransferase multiple interactions ISO meloxicam inhibits the reaction [Aluminum results in decreased expression of CHAT protein] CTD PMID:16928369 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131 		JBrowse link
G Ereg epiregulin multiple interactions ISO [meloxicam results in decreased activity of PTGS2 protein] inhibits the reaction [trans-10,cis-12-conjugated linoleic acid results in increased expression of EREG mRNA] CTD PMID:22583689 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO meloxicam inhibits the reaction [Paraquat results in decreased expression of GCLC protein] CTD PMID:20851755 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468 		JBrowse link