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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:oxadiazane
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Accession:CHEBI:48898 term browser browse the term
Synonyms:related_synonym: oxadiazanes


show annotations for term's descendants           Sort by:
(E)-thiamethoxam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa10 annexin A10 increases expression ISO Thiamethoxam results in increased expression of ANXA10 mRNA CTD PMID:32194361 NCBI chr16:27,738,712...27,805,648
Ensembl chr16:27,738,712...27,805,648 		JBrowse link
G Ar androgen receptor affects binding ISO Thiamethoxam binds to AR protein CTD PMID:31550567 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arg1 arginase 1 decreases expression ISO Thiamethoxam results in decreased expression of ARG1 mRNA CTD PMID:32194361 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Thiamethoxam results in increased expression of ATF3 mRNA CTD PMID:33533595 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Thiamethoxam results in increased expression of BAX protein CTD PMID:33533595 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Thiamethoxam results in decreased expression of BCL2 protein CTD PMID:33533595 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl6 BCL6, transcription repressor decreases expression ISO Thiamethoxam results in decreased expression of BCL6 mRNA CTD PMID:33533595 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Btg1 BTG anti-proliferation factor 1 increases expression ISO Thiamethoxam results in increased expression of BTG1 mRNA CTD PMID:33533595 NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649 		JBrowse link
G Casp3 caspase 3 increases cleavage ISO Thiamethoxam results in increased cleavage of CASP3 protein CTD PMID:33533595 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase increases expression
multiple interactions
decreases activity		 ISO
EXP		 Thiamethoxam results in increased expression of CAT mRNA
Plant Extracts inhibits the reaction [Thiamethoxam results in decreased activity of CAT protein]		 CTD PMID:33533595 PMID:34181816 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Thiamethoxam results in increased expression of CCL2 mRNA CTD PMID:33533595 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP Thiamethoxam results in increased activity of [NACHRA1 protein co-treated with CHRNB2 protein] CTD PMID:16981889 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression
multiple interactions		 EXP Thiamethoxam results in decreased expression of CYP11A1 mRNA
Plant Extracts inhibits the reaction [Thiamethoxam results in decreased expression of CYP11A1 mRNA]		 CTD PMID:34181816 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression
multiple interactions		 EXP Thiamethoxam results in decreased expression of CYP17A1 mRNA
Plant Extracts inhibits the reaction [Thiamethoxam results in decreased expression of CYP17A1 mRNA]		 CTD PMID:34181816 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression
increases activity
multiple interactions		 ISO
EXP		 Thiamethoxam results in increased expression of CYP19A1 mRNA
Thiamethoxam results in increased activity of CYP19A1 protein
Plant Extracts inhibits the reaction [Thiamethoxam results in increased expression of CYP19A1 mRNA]		 CTD PMID:26464060 PMID:28750898 PMID:34181816 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases expression ISO Thiamethoxam results in decreased expression of CYP2C19 protein CTD PMID:32194361 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [NADP co-treated with CYP3A4 protein] results in increased activity of Thiamethoxam CTD PMID:16153789 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO Thiamethoxam results in decreased expression of CYP7A1 protein CTD PMID:32194361 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Thiamethoxam results in increased expression of DDIT3 mRNA; Thiamethoxam results in increased expression of DDIT3 protein CTD PMID:33533595 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Esr1 estrogen receptor 1 affects binding
decreases expression		 ISO Thiamethoxam binds to ESR1 protein
Thiamethoxam results in decreased expression of ESR1 protein		 CTD PMID:31550567 PMID:33533595 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Foxo3 forkhead box O3 increases expression ISO Thiamethoxam results in increased expression of FOXO3 mRNA CTD PMID:33533595 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Fshr follicle stimulating hormone receptor decreases expression ISO Thiamethoxam results in decreased expression of FSHR protein CTD PMID:33533595 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO Thiamethoxam results in decreased expression of G6PC1 mRNA CTD PMID:32194361 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta decreases expression ISO Thiamethoxam results in decreased expression of GADD45B mRNA CTD PMID:33533595 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Gpt glutamic--pyruvic transaminase decreases activity EXP Thiamethoxam results in decreased activity of GPT protein CTD PMID:29197058 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO Thiamethoxam results in increased expression of GPX1 mRNA CTD PMID:33533595 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions
decreases expression		 EXP Plant Extracts inhibits the reaction [Thiamethoxam results in decreased expression of HSD3B1 mRNA] CTD PMID:34181816 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO Thiamethoxam results in increased expression of HSPA5 mRNA; Thiamethoxam results in increased expression of HSPA5 protein CTD PMID:33533595 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 decreases expression ISO Thiamethoxam results in decreased expression of ITPR1 mRNA CTD PMID:33533595 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Thiamethoxam results in decreased expression of JUNB mRNA CTD PMID:33533595 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor decreases expression
increases expression
multiple interactions		 ISO
EXP		 Thiamethoxam results in decreased expression of LHCGR protein
Thiamethoxam results in increased expression of LHCGR mRNA
Plant Extracts inhibits the reaction [Thiamethoxam results in increased expression of LHCGR mRNA]		 CTD PMID:33533595 PMID:34181816 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Lst1 leukocyte specific transcript 1 increases expression ISO Thiamethoxam results in increased expression of LST1 mRNA CTD PMID:33533595 NCBI chr20:3,634,680...3,639,731
Ensembl chr20:3,634,749...3,637,997 		JBrowse link
G Mc4r melanocortin 4 receptor decreases expression ISO Thiamethoxam results in decreased expression of MC4R mRNA CTD PMID:33533595 NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719 		JBrowse link
G Mmp7 matrix metallopeptidase 7 increases expression ISO Thiamethoxam results in increased expression of MMP7 mRNA CTD PMID:33533595 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
G Nos2 nitric oxide synthase 2 decreases activity
multiple interactions		 ISO Thiamethoxam metabolite results in decreased activity of NOS2 protein
[Thiamethoxam metabolite results in decreased activity of NOS2 protein] which results in increased chemical synthesis of Formaldehyde		 CTD PMID:29197058 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Plcg2 phospholipase C, gamma 2 decreases expression ISO Thiamethoxam results in decreased expression of PLCG2 mRNA CTD PMID:33533595 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Prnp prion protein increases expression ISO Thiamethoxam results in increased expression of PRNP mRNA CTD PMID:33533595 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Thiamethoxam results in decreased expression of PTGS2 mRNA CTD PMID:33533595 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pthlh parathyroid hormone-like hormone decreases expression ISO Thiamethoxam results in decreased expression of PTHLH mRNA CTD PMID:33533595 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847 		JBrowse link
G Ptx3 pentraxin 3 increases expression ISO Thiamethoxam results in increased expression of PTX3 mRNA CTD PMID:33533595 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions
decreases expression		 EXP Plant Extracts inhibits the reaction [Thiamethoxam results in decreased expression of SCARB1 mRNA] CTD PMID:34181816 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Sesn2 sestrin 2 increases expression ISO Thiamethoxam results in increased expression of SESN2 mRNA CTD PMID:33533595 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases activity ISO Thiamethoxam results in decreased activity of SLC22A2 protein CTD PMID:31364238 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Thiamethoxam results in increased expression of SLC7A11 mRNA CTD PMID:33533595 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression
multiple interactions		 EXP Thiamethoxam results in decreased expression of STAR mRNA
Plant Extracts inhibits the reaction [Thiamethoxam results in decreased expression of STAR mRNA]		 CTD PMID:34181816 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Stc2 stanniocalcin 2 increases expression ISO Thiamethoxam results in increased expression of STC2 mRNA CTD PMID:33533595 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973 		JBrowse link
G Thbs4 thrombospondin 4 decreases expression ISO Thiamethoxam results in decreased expression of THBS4 mRNA CTD PMID:33533595 NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313 		JBrowse link
G Thra thyroid hormone receptor alpha affects binding ISO Thiamethoxam binds to THRA protein CTD PMID:31550567 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Tnnt2 troponin T2, cardiac type increases secretion
multiple interactions		 EXP Thiamethoxam results in increased secretion of TNNT2 protein
fenugreek seed meal inhibits the reaction [Thiamethoxam results in increased secretion of TNNT2 protein]; Polysaccharides inhibits the reaction [Thiamethoxam results in increased secretion of TNNT2 protein]		 CTD PMID:30520268 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388 		JBrowse link
thiamethoxam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa10 annexin A10 increases expression ISO Thiamethoxam results in increased expression of ANXA10 mRNA CTD PMID:32194361 NCBI chr16:27,738,712...27,805,648
Ensembl chr16:27,738,712...27,805,648 		JBrowse link
G Ar androgen receptor affects binding ISO Thiamethoxam binds to AR protein CTD PMID:31550567 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arg1 arginase 1 decreases expression ISO Thiamethoxam results in decreased expression of ARG1 mRNA CTD PMID:32194361 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Thiamethoxam results in increased expression of ATF3 mRNA CTD PMID:33533595 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Thiamethoxam results in increased expression of BAX protein CTD PMID:33533595 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Thiamethoxam results in decreased expression of BCL2 protein CTD PMID:33533595 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl6 BCL6, transcription repressor decreases expression ISO Thiamethoxam results in decreased expression of BCL6 mRNA CTD PMID:33533595 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Btg1 BTG anti-proliferation factor 1 increases expression ISO Thiamethoxam results in increased expression of BTG1 mRNA CTD PMID:33533595 NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649 		JBrowse link
G Casp3 caspase 3 increases cleavage ISO Thiamethoxam results in increased cleavage of CASP3 protein CTD PMID:33533595 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase increases expression
multiple interactions
decreases activity		 ISO
EXP		 Thiamethoxam results in increased expression of CAT mRNA
Plant Extracts inhibits the reaction [Thiamethoxam results in decreased activity of CAT protein]		 CTD PMID:33533595 PMID:34181816 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Thiamethoxam results in increased expression of CCL2 mRNA CTD PMID:33533595 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP thiamethoxam results in increased activity of [NACHRA1 protein co-treated with CHRNB2 protein] CTD PMID:16981889 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression		 EXP Plant Extracts inhibits the reaction [Thiamethoxam results in decreased expression of CYP11A1 mRNA] CTD PMID:34181816 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression
multiple interactions		 EXP Thiamethoxam results in decreased expression of CYP17A1 mRNA
Plant Extracts inhibits the reaction [Thiamethoxam results in decreased expression of CYP17A1 mRNA]		 CTD PMID:34181816 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression
multiple interactions
increases activity		 ISO
EXP		 thiamethoxam results in increased expression of CYP19A1 mRNA
Plant Extracts inhibits the reaction [Thiamethoxam results in increased expression of CYP19A1 mRNA]
thiamethoxam results in increased activity of CYP19A1 protein		 CTD PMID:26464060 PMID:28750898 PMID:34181816 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases expression ISO Thiamethoxam results in decreased expression of CYP2C19 protein CTD PMID:32194361 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [NADP co-treated with CYP3A4 protein] results in increased activity of Thiamethoxam CTD PMID:16153789 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO Thiamethoxam results in decreased expression of CYP7A1 protein CTD PMID:32194361 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Thiamethoxam results in increased expression of DDIT3 mRNA; Thiamethoxam results in increased expression of DDIT3 protein CTD PMID:33533595 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Esr1 estrogen receptor 1 affects binding
decreases expression		 ISO Thiamethoxam binds to ESR1 protein
Thiamethoxam results in decreased expression of ESR1 protein		 CTD PMID:31550567 PMID:33533595 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Foxo3 forkhead box O3 increases expression ISO Thiamethoxam results in increased expression of FOXO3 mRNA CTD PMID:33533595 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Fshr follicle stimulating hormone receptor decreases expression ISO Thiamethoxam results in decreased expression of FSHR protein CTD PMID:33533595 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO Thiamethoxam results in decreased expression of G6PC1 mRNA CTD PMID:32194361 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta decreases expression ISO Thiamethoxam results in decreased expression of GADD45B mRNA CTD PMID:33533595 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Gpt glutamic--pyruvic transaminase decreases activity EXP thiamethoxam results in decreased activity of GPT protein CTD PMID:29197058 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO Thiamethoxam results in increased expression of GPX1 mRNA CTD PMID:33533595 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression
multiple interactions		 EXP Thiamethoxam results in decreased expression of HSD3B1 mRNA
Plant Extracts inhibits the reaction [Thiamethoxam results in decreased expression of HSD3B1 mRNA]		 CTD PMID:34181816 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO Thiamethoxam results in increased expression of HSPA5 mRNA; Thiamethoxam results in increased expression of HSPA5 protein CTD PMID:33533595 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 decreases expression ISO Thiamethoxam results in decreased expression of ITPR1 mRNA CTD PMID:33533595 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Thiamethoxam results in decreased expression of JUNB mRNA CTD PMID:33533595 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor decreases expression
increases expression
multiple interactions		 ISO
EXP		 Thiamethoxam results in decreased expression of LHCGR protein
Thiamethoxam results in increased expression of LHCGR mRNA
Plant Extracts inhibits the reaction [Thiamethoxam results in increased expression of LHCGR mRNA]		 CTD PMID:33533595 PMID:34181816 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Lst1 leukocyte specific transcript 1 increases expression ISO Thiamethoxam results in increased expression of LST1 mRNA CTD PMID:33533595 NCBI chr20:3,634,680...3,639,731
Ensembl chr20:3,634,749...3,637,997 		JBrowse link
G Mc4r melanocortin 4 receptor decreases expression ISO Thiamethoxam results in decreased expression of MC4R mRNA CTD PMID:33533595 NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719 		JBrowse link
G Mmp7 matrix metallopeptidase 7 increases expression ISO Thiamethoxam results in increased expression of MMP7 mRNA CTD PMID:33533595 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases activity		 ISO [thiamethoxam metabolite results in decreased activity of NOS2 protein] which results in increased chemical synthesis of Formaldehyde CTD PMID:29197058 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Plcg2 phospholipase C, gamma 2 decreases expression ISO Thiamethoxam results in decreased expression of PLCG2 mRNA CTD PMID:33533595 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Prnp prion protein increases expression ISO Thiamethoxam results in increased expression of PRNP mRNA CTD PMID:33533595 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Thiamethoxam results in decreased expression of PTGS2 mRNA CTD PMID:33533595 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pthlh parathyroid hormone-like hormone decreases expression ISO Thiamethoxam results in decreased expression of PTHLH mRNA CTD PMID:33533595 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847 		JBrowse link
G Ptx3 pentraxin 3 increases expression ISO Thiamethoxam results in increased expression of PTX3 mRNA CTD PMID:33533595 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions
decreases expression		 EXP Plant Extracts inhibits the reaction [Thiamethoxam results in decreased expression of SCARB1 mRNA] CTD PMID:34181816 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Sesn2 sestrin 2 increases expression ISO Thiamethoxam results in increased expression of SESN2 mRNA CTD PMID:33533595 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases activity ISO Thiamethoxam results in decreased activity of SLC22A2 protein CTD PMID:31364238 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Thiamethoxam results in increased expression of SLC7A11 mRNA CTD PMID:33533595 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression
multiple interactions		 EXP Thiamethoxam results in decreased expression of STAR mRNA
Plant Extracts inhibits the reaction [Thiamethoxam results in decreased expression of STAR mRNA]		 CTD PMID:34181816 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Stc2 stanniocalcin 2 increases expression ISO Thiamethoxam results in increased expression of STC2 mRNA CTD PMID:33533595 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973 		JBrowse link
G Thbs4 thrombospondin 4 decreases expression ISO Thiamethoxam results in decreased expression of THBS4 mRNA CTD PMID:33533595 NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313 		JBrowse link
G Thra thyroid hormone receptor alpha affects binding ISO Thiamethoxam binds to THRA protein CTD PMID:31550567 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Tnnt2 troponin T2, cardiac type increases secretion
multiple interactions		 EXP Thiamethoxam results in increased secretion of TNNT2 protein
fenugreek seed meal inhibits the reaction [Thiamethoxam results in increased secretion of TNNT2 protein]; Polysaccharides inhibits the reaction [Thiamethoxam results in increased secretion of TNNT2 protein]		 CTD PMID:30520268 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    chemical entity 19816
      atom 19816
        nonmetal atom 19749
          nitrogen atom 18922
            nitrogen molecular entity 18922
              organonitrogen compound 18757
                organonitrogen heterocyclic compound 18027
                  oxadiazane 49
                    thiamethoxam + 49
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            organic molecule 19656
                              organic cyclic compound 19461
                                organic heterocyclic compound 18817
                                  organic heteromonocyclic compound 17582
                                    oxadiazane 49
                                      thiamethoxam + 49
paths to the root