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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sulfite salt
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Accession:CHEBI:48857 term browser browse the term


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sodium hydrogensulfite term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP 6-isopropoxy-9-oxoxanthene-2-carboxylic acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; [sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein; Ascorbic Acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Dizocilpine Maleate inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; KT 5720 inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; PTGS2 protein affects the susceptibility to [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Vitamin E inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein] CTD PMID:21873648 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 decreases expression EXP sodium bisulfite results in decreased expression of COX4 mRNA CTD PMID:26980303 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921 		JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 decreases expression EXP sodium bisulfite results in decreased expression of ATP6 mRNA CTD PMID:26980303 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599 		JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of ATP8 mRNA] CTD PMID:26980303 NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961 		JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of COX1 mRNA] CTD PMID:26980303 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867 		JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression EXP sodium bisulfite results in decreased expression of COX2 mRNA CTD PMID:26980303 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689 		JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III multiple interactions
decreases expression		 EXP TFAM protein inhibits the reaction [sodium bisulfite results in decreased expression of COX3 mRNA] CTD PMID:26980303 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO sodium bisulfite inhibits the reaction [Rotenone results in increased expression of NOS2 mRNA] CTD PMID:25086357 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nrf1 nuclear respiratory factor 1 multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of NRF1 mRNA]
sodium bisulfite results in decreased expression of NRF1 mRNA; sodium bisulfite results in decreased expression of NRF1 protein		 CTD PMID:26980303 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of PPARGC1A mRNA]
sodium bisulfite results in decreased expression of PPARGC1A mRNA; sodium bisulfite results in decreased expression of PPARGC1A protein		 CTD PMID:26980303 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Ptger2 prostaglandin E receptor 2 multiple interactions EXP [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGER2 protein CTD PMID:21873648 NCBI chr15:18,215,013...18,228,714
Ensembl chr15:18,217,285...18,228,714 		JBrowse link
G Ptger4 prostaglandin E receptor 4 multiple interactions EXP [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGER4 protein CTD PMID:21873648 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Ptges prostaglandin E synthase multiple interactions EXP [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGES mRNA CTD PMID:21873648 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptges2 prostaglandin E synthase 2 multiple interactions EXP [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGES2 mRNA CTD PMID:21873648 NCBI chr 3:15,690,501...15,697,688
Ensembl chr 3:15,690,501...15,697,688 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP [SC 560 results in decreased activity of PTGS1 protein] promotes the reaction [[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Dinoprostone]] CTD PMID:21873648 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO		 [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Cyclic AMP]; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Dinoprostone]; [SC 560 results in decreased activity of PTGS1 protein] promotes the reaction [[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Dinoprostone]]; [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGS2 protein; Ascorbic Acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGS2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGS2 protein]; PTGS2 protein affects the susceptibility to [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Vitamin E inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGS2 protein]
sodium bisulfite inhibits the reaction [Rotenone results in increased expression of PTGS2 mRNA]; sodium bisulfite inhibits the reaction [Rotenone results in increased expression of PTGS2 protein]		 CTD PMID:21873648 PMID:25086357 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of TFAM mRNA]; TFAM protein inhibits the reaction [sodium bisulfite results in decreased expression of COX3 mRNA]
sodium bisulfite results in decreased expression of TFAM mRNA; sodium bisulfite results in decreased expression of TFAM protein		 CTD PMID:26980303 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO sodium bisulfite inhibits the reaction [Rotenone results in increased expression of TNF mRNA] CTD PMID:25086357 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
sodium sulfite term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin multiple interactions ISO [NOS1 co-treated with sodium sulfite co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased oxidation of ALB protein CTD PMID:20348042 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP 6-isopropoxy-9-oxoxanthene-2-carboxylic acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; [sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein; Ascorbic Acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Dizocilpine Maleate inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; KT 5720 inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; PTGS2 protein affects the susceptibility to [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Vitamin E inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein] CTD PMID:21873648 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases export ISO sodium sulfite results in increased export of GPT protein CTD PMID:23973939 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions ISO [NOS1 co-treated with sodium sulfite co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased oxidation of ALB protein CTD PMID:20348042 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Ptger2 prostaglandin E receptor 2 multiple interactions EXP [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGER2 protein CTD PMID:21873648 NCBI chr15:18,215,013...18,228,714
Ensembl chr15:18,217,285...18,228,714 		JBrowse link
G Ptger4 prostaglandin E receptor 4 multiple interactions EXP [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGER4 protein CTD PMID:21873648 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Ptges prostaglandin E synthase multiple interactions EXP [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGES mRNA CTD PMID:21873648 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptges2 prostaglandin E synthase 2 multiple interactions EXP [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGES2 mRNA CTD PMID:21873648 NCBI chr 3:15,690,501...15,697,688
Ensembl chr 3:15,690,501...15,697,688 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP [SC 560 results in decreased activity of PTGS1 protein] promotes the reaction [[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Dinoprostone]] CTD PMID:21873648 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Cyclic AMP]; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Dinoprostone]; [SC 560 results in decreased activity of PTGS1 protein] promotes the reaction [[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Dinoprostone]]; [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGS2 protein; Ascorbic Acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGS2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGS2 protein]; PTGS2 protein affects the susceptibility to [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Vitamin E inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGS2 protein] CTD PMID:21873648 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 increases expression ISO sodium sulfite results in increased expression of RIPK1 protein CTD PMID:23973939 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    chemical entity 20088
      molecular entity 20058
        inorganic molecular entity 19773
          inorganic salt 12729
            sulfite salt 22
              Diammonium sulfite 0
              sodium hydrogensulfite 18
              sodium sulfite 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      chalcogen 19732
                        oxygen atom 19674
                          oxygen molecular entity 19674
                            hydroxides 19454
                              oxoacid 18744
                                oxoacid derivative 14452
                                  sulfur oxoacid derivative 12446
                                    sulfurous acid derivative 4410
                                      sulfites 4404
                                        sulfite salt 22
                                          Diammonium sulfite 0
                                          sodium hydrogensulfite 18
                                          sodium sulfite 11
paths to the root