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G |
Abcg2 |
ATP binding cassette subfamily G member 2 |
multiple interactions increases expression |
ISO |
4'-methoxy-1-naphthylfenoterol inhibits the reaction [AM 251 results in increased expression of ABCG2 protein]; 4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid inhibits the reaction [AM 251 results in increased expression of ABCG2 protein] |
CTD |
PMID:27423937 |
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NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
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G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions |
ISO |
AM 251 inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA] |
CTD |
PMID:27936102 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Agrp |
agouti related neuropeptide |
multiple interactions increases expression |
EXP |
AM 251 promotes the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of AGRP mRNA] AM 251 results in increased expression of AGRP mRNA |
CTD |
PMID:26468265 |
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NCBI chr19:33,447,992...33,523,068
Ensembl chr19:33,447,992...33,449,584
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Cannabidiol results in increased phosphorylation of AKT1 protein]; AM 251 inhibits the reaction [Dronabinol results in decreased phosphorylation of and results in decreased activity of AKT1 protein] AM 251 inhibits the reaction [[3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide co-treated with Glutamic Acid] results in increased phosphorylation of AKT1 protein]; AM 251 inhibits the reaction [[cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester co-treated with Glutamic Acid] results in increased phosphorylation of AKT1 protein]; AM 251 inhibits the reaction [[JZL 184 co-treated with Glutamic Acid] results in increased phosphorylation of AKT1 protein]; AM 251 inhibits the reaction [Dietary Fats results in decreased expression of AKT1 protein] |
CTD |
PMID:17583570 PMID:26847930 PMID:27543109 PMID:33817834 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Arpc4 |
actin related protein 2/3 complex, subunit 4 |
decreases expression |
ISO |
AM 251 results in decreased expression of ARPC4 mRNA |
CTD |
PMID:16500647 |
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NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785
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G |
Arpp21 |
cAMP regulated phosphoprotein 21 |
increases expression |
ISO |
AM 251 results in increased expression of ARPP21 mRNA |
CTD |
PMID:16500647 |
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NCBI chr 8:112,034,636...112,199,273
Ensembl chr 8:112,034,642...112,194,297
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G |
Ass1 |
argininosuccinate synthase 1 |
increases expression |
ISO |
AM 251 results in increased expression of ASS1 mRNA |
CTD |
PMID:16500647 |
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NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
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G |
Atf5 |
activating transcription factor 5 |
increases expression |
ISO |
AM 251 results in increased expression of ATF5 mRNA |
CTD |
PMID:16500647 |
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NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
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G |
Avp |
arginine vasopressin |
multiple interactions increases expression |
EXP |
AM 251 promotes the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of AVP mRNA] AM 251 results in increased expression of AVP mRNA |
CTD |
PMID:26468265 |
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NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
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G |
Bcl2 |
BCL2, apoptosis regulator |
increases expression multiple interactions |
ISO |
AM 251 results in increased expression of BCL2 protein AM 251 inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein] |
CTD |
PMID:26967640 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bdkrb1 |
bradykinin receptor B1 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [anandamide results in decreased activity of BDKRB1 protein] |
CTD |
PMID:19022239 |
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NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
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G |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Morphine results in increased expression of BDNF protein] |
CTD |
PMID:27461790 |
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NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Btg2 |
BTG anti-proliferation factor 2 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Ethanol results in increased expression of BTG2 mRNA] |
CTD |
PMID:28095641 |
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NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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G |
Cap2 |
cyclase associated actin cytoskeleton regulatory protein 2 |
decreases expression |
ISO |
AM 251 results in decreased expression of CAP2 mRNA |
CTD |
PMID:16500647 |
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NCBI chr17:18,054,234...18,203,453
Ensembl chr17:18,054,431...18,203,373
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G |
Cars1 |
cysteinyl-tRNA synthetase 1 |
increases expression |
ISO |
AM 251 results in increased expression of CARS1 mRNA |
CTD |
PMID:16500647 |
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NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941
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G |
Cartpt |
CART prepropeptide |
increases expression multiple interactions |
EXP |
AM 251 results in increased expression of CARTPT mRNA [AM 251 co-treated with Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of CARTPT mRNA |
CTD |
PMID:26468265 |
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NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
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G |
Casp1 |
caspase 1 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of CASP1 protein]] |
CTD |
PMID:34269108 |
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NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Cavin2 |
caveolae associated protein 2 |
decreases expression |
ISO |
AM 251 results in decreased expression of CAVIN2 mRNA |
CTD |
PMID:16500647 |
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NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147
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G |
Ccdc86 |
coiled-coil domain containing 86 |
decreases expression |
ISO |
AM 251 results in decreased expression of CCDC86 mRNA |
CTD |
PMID:16500647 |
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NCBI chr 1:207,590,946...207,596,527
Ensembl chr 1:207,590,168...207,596,544
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G |
Ccnd2 |
cyclin D2 |
increases expression multiple interactions |
ISO |
AM 251 results in increased expression of CCND2 protein AM 251 inhibits the reaction [Streptozocin results in decreased expression of CCND2 protein] |
CTD |
PMID:26967640 |
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NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
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G |
Cd55 |
CD55 molecule (Cromer blood group) |
increases expression |
ISO |
AM 251 results in increased expression of CD55 mRNA |
CTD |
PMID:16500647 |
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NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
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G |
Cdh1 |
cadherin 1 |
increases expression multiple interactions |
ISO |
AM 251 results in increased expression of CDH1 protein AM 251 inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 protein] |
CTD |
PMID:27936102 |
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NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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G |
Cebpg |
CCAAT/enhancer binding protein gamma |
increases expression |
ISO |
AM 251 results in increased expression of CEBPG mRNA |
CTD |
PMID:16500647 |
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NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
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G |
Chrnb3 |
cholinergic receptor nicotinic beta 3 subunit |
increases expression |
ISO |
AM 251 results in increased expression of CHRNB3 mRNA |
CTD |
PMID:16500647 |
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NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360
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G |
Cklf |
chemokine-like factor |
increases expression |
ISO |
AM 251 results in increased expression of CKLF mRNA |
CTD |
PMID:16500647 |
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NCBI chr19:698,097...706,570
Ensembl chr19:698,033...706,570
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G |
Cnr1 |
cannabinoid receptor 1 |
multiple interactions decreases activity increases methylation |
ISO EXP |
[AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to 1-(5-fluoropentyl)-3-(1-naphthoyl)indole; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to 1-pentyl-3-(1-naphthoyl)indole; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to 4-ethylnaphthalen-1-yl-(1-pentylindol-3-yl)methanone; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to CP 47497; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to CP 47497 analog; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to HU 211; AM 251 inhibits the reaction [Dietary Fats results in increased expression of CNR1 protein]; AM 251 inhibits the reaction [Ethanol results in increased expression of CNR1 mRNA] [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased activity of nimesulide; AM 251 binds to and results in decreased activity of CNR1 protein; AM 251 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of CNR1 mRNA]; AM 251 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of CNR1 protein]; AM 251 inhibits the reaction [1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester binds to and results in increased activity of CNR1 protein]; AM 251 inhibits the reaction [1-pentyfluoro-1H-indole-3-carboxylic acid 8-quinolinyl ester binds to and results in increased activity of CNR1 protein]; AM 251 inhibits the reaction [Dietary Carbohydrates results in decreased expression of CNR1 protein]; AM 251 inhibits the reaction [HU 211 results in decreased expression of CNR1 protein]; AM 251 inhibits the reaction [Methylazoxymethanol Acetate results in increased expression of CNR1 mRNA]; AM 251 inhibits the reaction [N-(1-adamantyl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide binds to and results in increased activity of CNR1 protein]; AM 251 inhibits the reaction [N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide binds to and results in increased activity of CNR1 protein] AM 251 results in decreased activity of CNR1 protein AM 251 results in increased methylation of CNR1 promoter AM 251 inhibits the reaction [Cannabidiol results in increased expression of CNR1 protein] |
CTD |
PMID:12509806 PMID:17596442 PMID:20590570 PMID:21907772 PMID:24211273 PMID:26671069 PMID:26686391 PMID:26847930 PMID:27071101 PMID:27114535 PMID:28095641 PMID:29113897 PMID:29883990 PMID:29982505 PMID:30496751 PMID:31199905 PMID:31622603 PMID:33817834 More...
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NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions |
ISO |
AM 251 inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] |
CTD |
PMID:27936102 |
|
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col1a2 |
collagen type I alpha 2 chain |
multiple interactions |
ISO |
AM 251 inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA] |
CTD |
PMID:27936102 |
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NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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G |
Col4a1 |
collagen type IV alpha 1 chain |
multiple interactions |
ISO |
AM 251 inhibits the reaction [TGFB1 protein results in increased expression of COL4A1 mRNA] |
CTD |
PMID:27936102 |
|
NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
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G |
Cox4i1 |
cytochrome c oxidase subunit 4i1 |
multiple interactions |
EXP |
AM 251 inhibits the reaction [Dietary Carbohydrates results in decreased expression of COX4I1 mRNA]; AM 251 inhibits the reaction [Dietary Fats results in decreased expression of COX4I1 mRNA] |
CTD |
PMID:26671069 |
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NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Dietary Fats results in decreased expression of CPT1A mRNA] |
CTD |
PMID:26847930 |
|
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Morphine results in increased phosphorylation of CREB1 protein] |
CTD |
PMID:27461790 |
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NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Creb3l3 |
cAMP responsive element binding protein 3-like 3 |
multiple interactions decreases expression |
ISO |
AM 251 inhibits the reaction [Ethanol results in increased cleavage of and results in increased activity of CREB3L3 protein]; AM 251 inhibits the reaction [Ethanol results in increased expression of CREB3L3 mRNA] AM 251 results in decreased expression of CREB3L3 mRNA |
CTD |
PMID:23894352 |
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NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048
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G |
Crh |
corticotropin releasing hormone |
multiple interactions increases expression |
EXP |
[AM 251 co-treated with Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of CRH mRNA AM 251 results in increased expression of CRH mRNA |
CTD |
PMID:26468265 |
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NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
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G |
Cs |
citrate synthase |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Dietary Fats results in decreased expression of CS mRNA] |
CTD |
PMID:26847930 |
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NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
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G |
Cth |
cystathionine gamma-lyase |
increases expression |
ISO |
AM 251 results in increased expression of CTH mRNA |
CTD |
PMID:16500647 |
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NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]; AM 251 promotes the reaction [iodopravadoline inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]]; iodopravadoline promotes the reaction [AM 251 inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]] |
CTD |
PMID:17484889 |
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NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
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G |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Ethanol results in increased expression of CYP27A1 mRNA] |
CTD |
PMID:23894352 PMID:28095641 |
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NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Ethanol results in increased expression of CYP7A1 mRNA] |
CTD |
PMID:23894352 PMID:28095641 |
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NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G |
Cyp7b1 |
cytochrome P450 family 7 subfamily B member 1 |
decreases expression multiple interactions |
ISO |
AM 251 results in decreased expression of CYP7B1 mRNA AM 251 inhibits the reaction [Ethanol results in increased expression of CYP7B1 mRNA] |
CTD |
PMID:23894352 |
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NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
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G |
Cyp8b1 |
cytochrome P450 family 8 subfamily B member 1 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Ethanol results in increased expression of CYP8B1 mRNA] |
CTD |
PMID:23894352 PMID:28095641 |
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NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression |
ISO |
AM 251 results in increased expression of DDIT3 mRNA |
CTD |
PMID:16500647 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddit4 |
DNA-damage-inducible transcript 4 |
increases expression |
ISO |
AM 251 results in increased expression of DDIT4 mRNA |
CTD |
PMID:16500647 |
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NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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G |
Dhx9 |
DExH-box helicase 9 |
decreases expression |
ISO |
AM 251 results in decreased expression of DHX9 mRNA |
CTD |
PMID:16500647 |
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NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
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G |
Dld |
dihydrolipoamide dehydrogenase |
multiple interactions increases activity decreases expression |
EXP ISO |
AM 251 inhibits the reaction [Dietary Carbohydrates results in decreased expression of DLD mRNA]; AM 251 inhibits the reaction [Dietary Carbohydrates results in decreased expression of DLD protein] AM 251 results in increased activity of DLD protein AM 251 results in decreased expression of DLD mRNA AM 251 promotes the reaction [INS1 protein results in increased activity of DLD protein] |
CTD |
PMID:26671069 |
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NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
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G |
Eftud2 |
elongation factor Tu GTP binding domain containing 2 |
decreases expression |
ISO |
AM 251 results in decreased expression of EFTUD2 mRNA |
CTD |
PMID:16500647 |
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NCBI chr10:87,804,893...87,852,181
Ensembl chr10:87,804,892...87,846,079
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions increases expression |
ISO |
4'-methoxy-1-naphthylfenoterol inhibits the reaction [AM 251 results in increased expression of EGFR protein]; 4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid inhibits the reaction [AM 251 results in increased expression of EGFR protein] |
CTD |
PMID:27423937 |
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NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Eno3 |
enolase 3 |
multiple interactions |
EXP |
AM 251 inhibits the reaction [Dietary Carbohydrates results in increased expression of ENO3 protein] |
CTD |
PMID:26671069 |
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NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921
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G |
Ervfrd-1 |
endogenous retrovirus group FRD member 1, envelope |
multiple interactions |
ISO |
AM 251 affects the reaction [Dronabinol results in decreased expression of ERVFRD-1 mRNA] |
CTD |
PMID:26070387 |
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NCBI chr12:22,151,211...22,158,264
Ensembl chr12:22,151,211...22,158,264
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G |
F3 |
coagulation factor III, tissue factor |
multiple interactions |
ISO |
[AM 251 co-treated with iodopravadoline] promotes the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]; [AM 251 co-treated with iodopravadoline] promotes the reaction [methanandamide promotes the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]] |
CTD |
PMID:27556861 |
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NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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G |
Fen1 |
flap structure-specific endonuclease 1 |
decreases expression |
ISO |
AM 251 results in decreased expression of FEN1 mRNA |
CTD |
PMID:16500647 |
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NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Dietary Fats results in increased expression of FOS protein]; AM 251 inhibits the reaction [LEP gene mutant form results in increased expression of FOS protein] |
CTD |
PMID:27071101 |
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Fosb |
FosB proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
ISO |
AM 251 inhibits the reaction [TGFB1 protein results in increased expression of FOSB mRNA] AM 251 results in increased expression of FOSB mRNA |
CTD |
PMID:27936102 |
|
NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
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G |
Foxo1 |
forkhead box O1 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Dietary Fats results in decreased phosphorylation of FOXO1 protein] |
CTD |
PMID:26847930 |
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NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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G |
Fra10ac1 |
FRA10A associated CGG repeat 1 |
increases expression |
ISO |
AM 251 results in increased expression of FRA10AC1 mRNA |
CTD |
PMID:16500647 |
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NCBI chr 1:235,969,071...236,001,074
Ensembl chr 1:235,969,112...236,001,210
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Dietary Fats results in increased expression of G6PC protein] |
CTD |
PMID:26847930 |
|
NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
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G |
Glo1 |
glyoxalase 1 |
decreases expression multiple interactions |
EXP |
AM 251 results in decreased expression of GLO1 protein AM 251 inhibits the reaction [Dietary Carbohydrates results in decreased expression of GLO1 protein]; AM 251 inhibits the reaction [Dietary Fats results in decreased expression of GLO1 protein] |
CTD |
PMID:26671069 |
|
NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
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G |
Gpi |
glucose-6-phosphate isomerase |
multiple interactions decreases expression |
EXP |
AM 251 inhibits the reaction [Dietary Carbohydrates results in increased expression of GPI protein] AM 251 results in decreased expression of GPI protein |
CTD |
PMID:26671069 |
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NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
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G |
Gpr55 |
G protein-coupled receptor 55 |
multiple interactions increases activity |
ISO |
4'-methoxy-1-naphthylfenoterol inhibits the reaction [AM 251 results in increased activity of GPR55 protein]; 4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid inhibits the reaction [AM 251 results in increased activity of GPR55 protein] |
CTD |
PMID:27423937 |
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NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613
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G |
Gpx1 |
glutathione peroxidase 1 |
increases expression |
ISO |
AM 251 results in increased expression of GPX1 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gsr |
glutathione-disulfide reductase |
multiple interactions |
ISO |
AM 251 promotes the reaction [INS1 protein results in increased activity of GSR protein] |
CTD |
PMID:26671069 |
|
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Gtf3c5 |
general transcription factor IIIC subunit 5 |
decreases expression |
ISO |
AM 251 results in decreased expression of GTF3C5 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 3:11,893,867...11,914,187
Ensembl chr 3:11,893,875...11,914,180
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G |
Hax1 |
HCLS1 associated protein X-1 |
increases expression |
ISO |
AM 251 results in increased expression of HAX1 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 2:175,434,242...175,437,926
Ensembl chr 2:175,434,238...175,437,714
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G |
Hcrt |
hypocretin neuropeptide precursor |
multiple interactions |
EXP ISO |
AM 251 inhibits the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of HCRT mRNA] AM 251 inhibits the reaction [Dietary Fats results in increased expression of HCRT protein modified form]; AM 251 inhibits the reaction [HCRT protein modified form results in increased expression of POMC mRNA]; AM 251 inhibits the reaction [HCRT protein modified form results in increased expression of POMC protein modified form]; AM 251 inhibits the reaction [HCRT protein modified form results in increased expression of POMC protein]; AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of and results in increased activity of STAT3 protein]; AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of MAPK1 protein]; AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of MAPK3 protein]; AM 251 inhibits the reaction [LEP gene mutant form results in increased expression of HCRT protein modified form] |
CTD |
PMID:26468265 PMID:27071101 |
|
NCBI chr10:85,689,992...85,691,206
Ensembl chr10:85,689,465...85,691,210
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G |
Hmox1 |
heme oxygenase 1 |
increases expression |
ISO |
AM 251 results in increased expression of HMOX1 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hnmt |
histamine N-methyltransferase |
increases expression |
ISO |
AM 251 results in increased expression of HNMT mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012
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G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
decreases expression |
ISO |
AM 251 results in decreased expression of HSPA1B mRNA |
CTD |
PMID:16500647 |
|
NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
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|
G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
decreases expression |
ISO |
AM 251 results in decreased expression of HSPA8 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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|
G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Cannabidiol results in increased expression of ICAM1 mRNA] |
CTD |
PMID:22198381 |
|
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
[AM 251 co-treated with iodopravadoline] promotes the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]; [AM 251 co-treated with iodopravadoline] promotes the reaction [methanandamide promotes the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]] |
CTD |
PMID:27556861 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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|
G |
Il33 |
interleukin 33 |
multiple interactions |
EXP |
AM 251 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Carbon Monoxide results in increased expression of IL33 protein]] |
CTD |
PMID:31732924 |
|
NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
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G |
Immp2l |
inner mitochondrial membrane peptidase subunit 2 |
increases expression |
ISO |
AM 251 results in increased expression of IMMP2L mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 6:58,070,035...58,970,165
Ensembl chr 6:58,070,283...58,969,840
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|
G |
Ins1 |
insulin 1 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; AM 251 promotes the reaction [INS1 protein results in increased activity of DLD protein]; AM 251 promotes the reaction [INS1 protein results in increased activity of GSR protein] |
CTD |
PMID:26671069 PMID:26967640 |
|
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Irf2bpl |
interferon regulatory factor 2 binding protein-like |
increases expression |
ISO |
AM 251 results in increased expression of IRF2BPL mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 6:106,527,179...106,531,294
Ensembl chr 6:106,528,053...106,530,401
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G |
Irs2 |
insulin receptor substrate 2 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Dietary Fats results in decreased phosphorylation of IRS2 protein] |
CTD |
PMID:26847930 |
|
NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
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G |
Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
AM 251 inhibits the reaction [TGFB1 protein results in increased expression of JUNB mRNA] |
CTD |
PMID:27936102 |
|
NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
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G |
Ldha |
lactate dehydrogenase A |
multiple interactions |
EXP |
AM 251 inhibits the reaction [Dietary Carbohydrates results in increased expression of LDHA protein] |
CTD |
PMID:26671069 |
|
NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
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G |
Lep |
leptin |
multiple interactions |
ISO |
AM 251 inhibits the reaction [LEP gene mutant form results in decreased expression of POMC mRNA]; AM 251 inhibits the reaction [LEP gene mutant form results in decreased expression of POMC protein]; AM 251 inhibits the reaction [LEP gene mutant form results in decreased secretion of POMC protein modified form]; AM 251 inhibits the reaction [LEP gene mutant form results in increased expression of FOS protein]; AM 251 inhibits the reaction [LEP gene mutant form results in increased expression of HCRT protein modified form] |
CTD |
PMID:27071101 |
|
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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|
G |
Lmnb2 |
lamin B2 |
decreases expression |
ISO |
AM 251 results in decreased expression of LMNB2 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665
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G |
LOC103690190 |
histone H2A type 1-E |
increases expression |
ISO |
AM 251 results in increased expression of H2AC6 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr17:42,707,863...42,708,420
|
|
G |
Map2k3 |
mitogen activated protein kinase kinase 3 |
decreases expression |
ISO |
AM 251 results in decreased expression of MAP2K3 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO |
AM 251 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; AM 251 inhibits the reaction [Dronabinol results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]; AM 251 inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK1 protein]; AM 251 inhibits the reaction [methanandamide results in increased phosphorylation of MAPK1 protein] AM 251 results in increased phosphorylation of MAPK1 protein AM 251 inhibits the reaction [[3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide co-treated with Glutamic Acid] results in increased phosphorylation of MAPK1 protein]; AM 251 inhibits the reaction [[cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester co-treated with Glutamic Acid] results in increased phosphorylation of MAPK1 protein]; AM 251 inhibits the reaction [[JZL 184 co-treated with Glutamic Acid] results in increased phosphorylation of MAPK1 protein]; AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of MAPK1 protein]; AM 251 inhibits the reaction [Morphine results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:17583570 PMID:17596442 PMID:18159069 PMID:19477951 PMID:27071101 PMID:27461790 PMID:27543109 PMID:29285308 More...
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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|
G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO |
AM 251 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; AM 251 inhibits the reaction [Dronabinol results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]; AM 251 inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK3 protein]; AM 251 inhibits the reaction [methanandamide results in increased phosphorylation of MAPK3 protein] AM 251 results in increased phosphorylation of MAPK3 protein AM 251 inhibits the reaction [[3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide co-treated with Glutamic Acid] results in increased phosphorylation of MAPK3 protein]; AM 251 inhibits the reaction [[cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester co-treated with Glutamic Acid] results in increased phosphorylation of MAPK3 protein]; AM 251 inhibits the reaction [[JZL 184 co-treated with Glutamic Acid] results in increased phosphorylation of MAPK3 protein]; AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of MAPK3 protein]; AM 251 inhibits the reaction [Morphine results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:17583570 PMID:17596442 PMID:18159069 PMID:19477951 PMID:27071101 PMID:27461790 PMID:27543109 PMID:29285308 More...
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|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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|
G |
Mcm3 |
minichromosome maintenance complex component 3 |
decreases expression |
ISO |
AM 251 results in decreased expression of MCM3 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
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|
G |
Mcm5 |
minichromosome maintenance complex component 5 |
decreases expression |
ISO |
AM 251 results in decreased expression of MCM5 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
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G |
Mfn2 |
mitofusin 2 |
decreases expression |
ISO |
AM 251 results in decreased expression of MFN2 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
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|
G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions increases expression |
ISO |
AM 251 inhibits the reaction [TGFB1 protein results in increased expression of MMP2 mRNA] AM 251 results in increased expression of MMP2 protein |
CTD |
PMID:27936102 PMID:29883990 |
|
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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|
G |
Ncapd3 |
non-SMC condensin II complex, subunit D3 |
decreases expression |
ISO |
AM 251 results in decreased expression of NCAPD3 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 8:25,437,067...25,506,375
Ensembl chr 8:25,437,123...25,506,373
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G |
Ncoa7 |
nuclear receptor coactivator 7 |
increases expression |
ISO |
AM 251 results in increased expression of NCOA7 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 1:26,856,228...27,016,950
Ensembl chr 1:26,856,530...27,015,871
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G |
Npy |
neuropeptide Y |
multiple interactions |
EXP |
[AM 251 co-treated with Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of NPY mRNA |
CTD |
PMID:26468265 |
|
NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
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G |
Nrf1 |
nuclear respiratory factor 1 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Dietary Fats results in decreased expression of NRF1 mRNA] |
CTD |
PMID:26847930 |
|
NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
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G |
Oprl1 |
opioid related nociceptin receptor 1 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Dronabinol results in decreased expression of OPRL1 mRNA]; AM 251 inhibits the reaction [Dronabinol results in decreased expression of OPRL1 protein] |
CTD |
PMID:21603976 |
|
NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
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G |
Oxt |
oxytocin/neurophysin I prepropeptide |
multiple interactions increases expression increases secretion |
EXP |
AM 251 promotes the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of OXT mRNA] AM 251 results in increased expression of OXT mRNA AM 251 results in increased secretion of OXT protein |
CTD |
PMID:26468265 |
|
NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
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G |
Papola |
poly (A) polymerase alpha |
decreases expression |
ISO |
AM 251 results in decreased expression of PAPOLA mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 6:124,682,015...124,734,706
Ensembl chr 6:124,682,105...124,734,468
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [HU 211 results in increased cleavage of PARP1 protein] |
CTD |
PMID:19509271 |
|
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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|
G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Dietary Fats results in increased expression of PCK1 mRNA]; AM 251 inhibits the reaction [Dietary Fats results in increased expression of PCK1 protein] |
CTD |
PMID:26847930 |
|
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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G |
Pea15 |
proliferation and apoptosis adaptor protein 15 |
increases expression |
ISO |
AM 251 results in increased expression of PEA15 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499
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G |
Pomc |
proopiomelanocortin |
multiple interactions increases expression |
EXP ISO |
AM 251 promotes the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of POMC mRNA] AM 251 results in increased expression of POMC mRNA AM 251 inhibits the reaction [Dietary Fats results in decreased expression of POMC mRNA]; AM 251 inhibits the reaction [Dietary Fats results in decreased expression of POMC protein]; AM 251 inhibits the reaction [Dietary Fats results in decreased secretion of POMC protein modified form]; AM 251 inhibits the reaction [HCRT protein modified form results in increased expression of POMC mRNA]; AM 251 inhibits the reaction [HCRT protein modified form results in increased expression of POMC protein modified form]; AM 251 inhibits the reaction [HCRT protein modified form results in increased expression of POMC protein]; AM 251 inhibits the reaction [LEP gene mutant form results in decreased expression of POMC mRNA]; AM 251 inhibits the reaction [LEP gene mutant form results in decreased expression of POMC protein]; AM 251 inhibits the reaction [LEP gene mutant form results in decreased secretion of POMC protein modified form] |
CTD |
PMID:26468265 PMID:27071101 |
|
NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
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G |
Ppif |
peptidylprolyl isomerase F |
decreases expression |
ISO |
AM 251 results in decreased expression of PPIF mRNA |
CTD |
PMID:16500647 |
|
NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
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G |
Ptbp1 |
polypyrimidine tract binding protein 1 |
decreases expression |
ISO |
AM 251 results in decreased expression of PTBP1 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 7:9,842,574...9,852,332
Ensembl chr 7:9,842,574...9,852,397
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|
G |
Ptk2 |
protein tyrosine kinase 2 |
multiple interactions |
ISO |
[AM 251 co-treated with iodopravadoline] inhibits the reaction [Dronabinol results in increased phosphorylation of PTK2 protein] |
CTD |
PMID:31461164 |
|
NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
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|
G |
Racgap1 |
Rac GTPase-activating protein 1 |
decreases expression |
ISO |
AM 251 results in decreased expression of RACGAP1 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
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G |
Rad54l |
RAD54 like |
decreases expression |
ISO |
AM 251 results in decreased expression of RAD54L mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070
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G |
Rcc1 |
regulator of chromosome condensation 1 |
decreases expression |
ISO |
AM 251 results in decreased expression of RCC1 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 5:144,526,025...144,544,445
Ensembl chr 5:144,526,025...144,544,577
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G |
Rcc1l |
RCC1 like |
decreases expression |
ISO |
AM 251 results in decreased expression of RCC1L mRNA |
CTD |
PMID:16500647 |
|
NCBI chr12:22,543,125...22,574,042
Ensembl chr12:22,543,734...22,574,036
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G |
Rfc5 |
replication factor C subunit 5 |
decreases expression |
ISO |
AM 251 results in decreased expression of RFC5 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312
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G |
Rnaseh1 |
ribonuclease H1 |
increases expression |
ISO |
AM 251 results in increased expression of RNASEH1 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 6:45,282,849...45,292,258
Ensembl chr 6:45,282,854...45,292,236
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G |
Rpa1 |
replication protein A1 |
decreases expression |
ISO |
AM 251 results in decreased expression of RPA1 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr10:60,148,869...60,199,999
Ensembl chr10:60,148,793...60,199,949
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G |
Rwdd1 |
RWD domain containing 1 |
increases expression |
ISO |
AM 251 results in increased expression of RWDD1 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr20:25,949,723...25,967,147
Ensembl chr20:25,941,966...25,967,193
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G |
S100a2 |
S100 calcium binding protein A2 |
increases expression |
ISO |
AM 251 results in increased expression of S100A2 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 2:176,075,060...176,078,782
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|
G |
Sars1 |
seryl-tRNA synthetase 1 |
increases expression |
ISO |
AM 251 results in increased expression of SARS1 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277
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G |
Sesn2 |
sestrin 2 |
increases expression |
ISO |
AM 251 results in increased expression of SESN2 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
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G |
Slc18b1 |
solute carrier family 18 member B1 |
decreases expression |
ISO |
AM 251 results in decreased expression of SLC18B1 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr 1:21,628,232...21,670,807
Ensembl chr 1:21,628,237...21,670,684
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G |
Slc1a4 |
solute carrier family 1 member 4 |
increases expression |
ISO |
AM 251 results in increased expression of SLC1A4 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418
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|
G |
Slc30a1 |
solute carrier family 30 member 1 |
increases expression |
ISO |
AM 251 results in increased expression of SLC30A1 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
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G |
Slc46a1 |
solute carrier family 46 member 1 |
increases expression |
ISO |
AM 251 results in increased expression of SLC46A1 mRNA |
CTD |
PMID:19145103 |
|
NCBI chr10:63,361,504...63,367,940
Ensembl chr10:63,361,486...63,368,848
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G |
Slc6a3 |
solute carrier family 6 member 3 |
multiple interactions |
EXP |
AM 251 affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of SLC6A3 mRNA] |
CTD |
PMID:29113897 |
|
NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
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G |
Slc7a5 |
solute carrier family 7 member 5 |
increases expression |
ISO |
AM 251 results in increased expression of SLC7A5 mRNA |
CTD |
PMID:16500647 |
|
NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
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G |
Smad3 |
SMAD family member 3 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] |
CTD |
PMID:27936102 |
|
NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
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G |
Snai1 |
snail family transcriptional repressor 1 |
decreases expression multiple interactions |
ISO |
AM 251 results in decreased expression of SNAI1 mRNA AM 251 inhibits the reaction [TGFB1 protein results in increased expression of SNAI1 mRNA] |
CTD |
PMID:27936102 |
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NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
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G |
Snai2 |
snail family transcriptional repressor 2 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [TGFB1 protein results in increased expression of SNAI2 mRNA] |
CTD |
PMID:27936102 |
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NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
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G |
Sptbn1 |
spectrin, beta, non-erythrocytic 1 |
decreases expression |
ISO |
AM 251 results in decreased expression of SPTBN1 mRNA |
CTD |
PMID:16500647 |
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NCBI chr14:103,842,684...104,008,507
Ensembl chr14:103,842,684...104,008,507
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G |
Srsf1 |
serine and arginine rich splicing factor 1 |
decreases expression |
ISO |
AM 251 results in decreased expression of SRSF1 mRNA |
CTD |
PMID:16500647 |
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NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336
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G |
Stam |
signal transducing adaptor molecule |
decreases expression |
ISO |
AM 251 results in decreased expression of STAM mRNA |
CTD |
PMID:16500647 |
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NCBI chr17:77,120,235...77,166,173
Ensembl chr17:77,120,158...77,166,467
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G |
Stat3 |
signal transducer and activator of transcription 3 |
decreases expression multiple interactions |
ISO |
AM 251 results in decreased expression of STAT3 mRNA AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of and results in increased activity of STAT3 protein] AM 251 inhibits the reaction [Cannabidiol results in increased phosphorylation of STAT3 protein] |
CTD |
PMID:16500647 PMID:27071101 PMID:33817834 |
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NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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G |
Sugp2 |
SURP and G patch domain containing 2 |
decreases expression |
ISO |
AM 251 results in decreased expression of SUGP2 mRNA |
CTD |
PMID:16500647 |
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NCBI chr16:19,159,951...19,191,412
Ensembl chr16:19,164,767...19,191,340
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G |
Sun1 |
Sad1 and UNC84 domain containing 1 |
decreases expression |
ISO |
AM 251 results in decreased expression of SUN1 mRNA |
CTD |
PMID:16500647 |
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NCBI chr12:15,396,378...15,441,277
Ensembl chr12:15,396,381...15,441,571
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G |
Tacc3 |
transforming, acidic coiled-coil containing protein 3 |
decreases expression |
ISO |
AM 251 results in decreased expression of TACC3 mRNA |
CTD |
PMID:16500647 |
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NCBI chr14:77,051,209...77,065,343
Ensembl chr14:77,051,215...77,065,219
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G |
Tbl1x |
transducin (beta)-like 1 X-linked |
increases expression |
ISO |
AM 251 results in increased expression of TBL1X mRNA |
CTD |
PMID:16500647 |
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NCBI chr X:41,574,558...41,731,117
Ensembl chr X:41,576,047...41,731,101
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G |
Tfam |
transcription factor A, mitochondrial |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Dietary Fats results in decreased expression of TFAM mRNA] |
CTD |
PMID:26847930 |
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NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 protein]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of COL4A1 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of FOSB mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of JUNB mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of MMP2 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of SNAI1 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of SNAI2 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of TGFB2 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of TGFB3 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of TGFBR1 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] |
CTD |
PMID:27936102 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tgfb2 |
transforming growth factor, beta 2 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [TGFB1 protein results in increased expression of TGFB2 mRNA] |
CTD |
PMID:27936102 |
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NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
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G |
Tgfb3 |
transforming growth factor, beta 3 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [TGFB1 protein results in increased expression of TGFB3 mRNA] |
CTD |
PMID:27936102 |
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NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
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G |
Tgfbr1 |
transforming growth factor, beta receptor 1 |
multiple interactions |
ISO |
AM 251 inhibits the reaction [TGFB1 protein results in increased expression of TGFBR1 mRNA] |
CTD |
PMID:27936102 |
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NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
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G |
Th |
tyrosine hydroxylase |
multiple interactions |
EXP |
AM 251 affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of TH mRNA] |
CTD |
PMID:29113897 |
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NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions |
ISO |
[iodopravadoline co-treated with AM 251] inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]; [iodopravadoline co-treated with AM 251] inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]; AM 251 inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]; AM 251 inhibits the reaction [methanandamide results in increased expression of TIMP1 protein] |
CTD |
PMID:18159069 |
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NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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G |
Tmem126a |
transmembrane protein 126A |
increases expression |
ISO |
AM 251 results in increased expression of TMEM126A mRNA |
CTD |
PMID:16500647 |
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NCBI chr 1:144,422,698...144,430,730
Ensembl chr 1:144,422,703...144,430,628
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G |
Tnf |
tumor necrosis factor |
decreases response to substance |
ISO |
AM 251 results in decreased susceptibility to TNF protein |
CTD |
PMID:20626112 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Trib3 |
tribbles pseudokinase 3 |
increases expression |
ISO |
AM 251 results in increased expression of TRIB3 mRNA |
CTD |
PMID:16500647 |
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NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
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G |
Tspan10 |
tetraspanin 10 |
increases expression |
ISO |
AM 251 results in increased expression of TSPAN10 mRNA |
CTD |
PMID:16500647 |
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NCBI chr10:105,715,803...105,721,503
Ensembl chr10:105,715,961...105,719,813
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G |
Txnip |
thioredoxin interacting protein |
increases expression |
ISO |
AM 251 results in increased expression of TXNIP mRNA |
CTD |
PMID:16500647 |
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NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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G |
Ugcg |
UDP-glucose ceramide glucosyltransferase |
decreases expression |
ISO |
AM 251 results in decreased expression of UGCG mRNA |
CTD |
PMID:16500647 |
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NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
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G |
Uhrf1 |
ubiquitin-like with PHD and ring finger domains 1 |
decreases expression |
ISO |
AM 251 results in decreased expression of UHRF1 mRNA |
CTD |
PMID:16500647 |
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NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
ISO |
AM 251 inhibits the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of VEGFA protein]] |
CTD |
PMID:26467187 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Vegfc |
vascular endothelial growth factor C |
multiple interactions |
ISO |
AM 251 inhibits the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of VEGFC protein]] |
CTD |
PMID:26467187 |
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NCBI chr16:37,712,408...37,827,657
Ensembl chr16:37,712,262...37,827,848
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G |
Vldlr |
very low density lipoprotein receptor |
increases expression |
ISO |
AM 251 results in increased expression of VLDLR mRNA |
CTD |
PMID:16500647 |
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NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
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G |
Wars1 |
tryptophanyl-tRNA synthetase 1 |
increases expression |
ISO |
AM 251 results in increased expression of WARS1 mRNA |
CTD |
PMID:16500647 |
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NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269
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G |
Xbp1 |
X-box binding protein 1 |
increases expression |
ISO |
AM 251 results in increased expression of XBP1 mRNA |
CTD |
PMID:16500647 |
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NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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G |
Yars1 |
tyrosyl-tRNA synthetase 1 |
increases expression |
ISO |
AM 251 results in increased expression of YARS1 mRNA |
CTD |
PMID:16500647 |
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NCBI chr 5:141,535,815...141,564,029
Ensembl chr 5:141,535,759...141,563,833
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G |
Yy1 |
YY1 transcription factor |
multiple interactions |
ISO |
AM 251 inhibits the reaction [Ethanol results in increased expression of YY1 mRNA] |
CTD |
PMID:28095641 |
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NCBI chr 6:127,706,739...127,731,907
Ensembl chr 6:127,707,596...127,732,747
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G |
Zfp142 |
zinc finger protein 142 |
decreases expression |
ISO |
AM 251 results in decreased expression of ZNF142 mRNA |
CTD |
PMID:16500647 |
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NCBI chr 9:76,141,053...76,164,784
Ensembl chr 9:76,142,227...76,164,856
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G |
Zmym6 |
zinc finger MYM-type containing 6 |
increases expression |
ISO |
AM 251 results in increased expression of ZMYM6 mRNA |
CTD |
PMID:16500647 |
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NCBI chr 5:139,396,374...139,444,357
Ensembl chr 5:139,396,727...139,444,279
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G |
Acaca |
acetyl-CoA carboxylase alpha |
affects expression |
ISO |
Rimonabant affects the expression of ACACA mRNA |
CTD |
PMID:20110567 |
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NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Acacb |
acetyl-CoA carboxylase beta |
increases expression |
ISO |
Rimonabant results in increased expression of ACACB mRNA |
CTD |
PMID:20110567 |
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NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
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G |
Acadm |
acyl-CoA dehydrogenase medium chain |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of ACADM mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ACADM mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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G |
Acbd5 |
acyl-CoA binding domain containing 5 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ACBD5 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr17:85,206,178...85,248,909
Ensembl chr17:85,206,303...85,248,215
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G |
Acta2 |
actin alpha 2, smooth muscle |
decreases expression |
EXP |
Rimonabant results in decreased expression of ACTA2 mRNA |
CTD |
PMID:21863215 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Actr2 |
actin related protein 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ACTR2 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524
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G |
Adamts1 |
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ADAMTS1 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
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G |
Adgre1 |
adhesion G protein-coupled receptor E1 |
decreases expression |
EXP |
Rimonabant results in decreased expression of ADGRE1 mRNA |
CTD |
PMID:30365523 |
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NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
increases expression |
ISO |
Rimonabant results in increased expression of ADIPOQ mRNA; Rimonabant results in increased expression of ADIPOQ protein |
CTD |
PMID:16282221 PMID:20110567 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Agap2 |
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
multiple interactions increases expression |
ISO |
Rimonabant inhibits the reaction [MIR762 mRNA results in decreased expression of AGAP2 mRNA]; Rimonabant promotes the reaction [Dietary Fats results in increased expression of AGAP2 mRNA] Rimonabant results in increased expression of AGAP2 mRNA |
CTD |
PMID:30910812 |
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NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295
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G |
Akap2 |
A-kinase anchoring protein 2 |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PAKAP mRNA] Rimonabant affects the expression of PAKAP mRNA |
CTD |
PMID:19030233 |
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NCBI chr 5:72,536,986...72,648,524
Ensembl chr 5:72,181,718...72,648,524
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
EXP ISO |
Rimonabant inhibits the reaction [Dronabinol results in decreased phosphorylation of AKT1 protein] Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of AKT1 protein]; Rimonabant inhibits the reaction [methanandamide results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:12834810 PMID:31917333 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alkbh1 |
alkB homolog 1, histone H2A dioxygenase |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of ALKBH1 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 6:107,068,309...107,088,779
Ensembl chr 6:107,068,475...107,088,759
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G |
Anxa1 |
annexin A1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ANXA1 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
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G |
Anxa2 |
annexin A2 |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ANXA2 mRNA] Rimonabant affects the expression of ANXA2 mRNA |
CTD |
PMID:19030233 |
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NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
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G |
Apob |
apolipoprotein B |
increases secretion |
ISO |
Rimonabant results in increased secretion of APOB protein |
CTD |
PMID:20110567 |
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NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
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G |
App |
amyloid beta precursor protein |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of APP mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of APP mRNA] |
CTD |
PMID:19030233 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Arg1 |
arginase 1 |
multiple interactions |
ISO |
Rimonabant promotes the reaction [Dietary Fats results in increased expression of ARG1] |
CTD |
PMID:30910812 |
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NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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G |
Arhgef12 |
Rho guanine nucleotide exchange factor 12 |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of ARHGEF12 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ARHGEF12 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 8:43,350,070...43,475,404
Ensembl chr 8:43,353,799...43,476,366
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G |
Arpp19 |
cAMP-regulated phosphoprotein 19 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ARPP19 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 8:75,779,640...75,802,474
Ensembl chr 8:75,779,523...75,802,452
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G |
Arrb2 |
arrestin, beta 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR1 protein]]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR2 protein]] |
CTD |
PMID:27779402 |
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NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
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G |
Atf4 |
activating transcription factor 4 |
multiple interactions |
ISO |
[Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of ATF4 mRNA] |
CTD |
PMID:31054322 |
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions |
ISO |
[Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of ATF6 mRNA] |
CTD |
PMID:31054322 |
|
NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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G |
Atp5me |
ATP synthase membrane subunit e |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of ATP5K mRNA] |
CTD |
PMID:19030233 |
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NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013
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G |
Atrnl1 |
attractin like 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ATRNL1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 1:256,670,976...257,219,291
Ensembl chr 1:256,670,627...257,213,197
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G |
Aurkb |
aurora kinase B |
decreases expression |
ISO |
Rimonabant results in decreased expression of AURKB protein |
CTD |
PMID:19479993 |
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NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of BAX protein]] Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of BAX protein] |
CTD |
PMID:27932991 PMID:30769029 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in decreased expression of BCL2 protein]]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of BCL2 protein] |
CTD |
PMID:26967640 PMID:30769029 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dronabinol results in increased expression of BDNF mRNA] |
CTD |
PMID:20929960 |
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NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Braf |
B-Raf proto-oncogene, serine/threonine kinase |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of BRAF mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
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G |
Bzw1 |
basic leucine zipper and W2 domains 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of BZW1 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430
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G |
C1galt1 |
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of C1GALT1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 4:35,930,743...35,966,102
Ensembl chr 4:35,928,104...35,961,831
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G |
Cab39l |
calcium binding protein 39-like |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAB39L mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr15:33,606,588...33,710,518
Ensembl chr15:33,606,694...33,743,545
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G |
Calm1 |
calmodulin 1 |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CALM1 mRNA] Rimonabant affects the expression of CALM1 mRNA |
CTD |
PMID:19030233 |
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NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
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G |
Canx |
calnexin |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CANX mRNA] |
CTD |
PMID:19030233 |
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NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
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G |
Capn7 |
calpain 7 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAPN7 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr16:6,545,630...6,581,908
Ensembl chr16:6,545,731...6,581,905
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G |
Cartpt |
CART prepropeptide |
multiple interactions increases response to substance affects expression |
ISO |
FAAH affects the reaction [Rimonabant affects the expression of CARTPT protein] CARTPT results in increased susceptibility to Rimonabant |
CTD |
PMID:16131814 |
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NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
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G |
Casp1 |
caspase 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of CASP1 protein] |
CTD |
PMID:27932991 |
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NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp12 |
caspase 12 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CASP12 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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G |
Casp3 |
caspase 3 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [XLR-11 results in increased activity of CASP3 protein] Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased cleavage of CASP3 protein]]; Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]] |
CTD |
PMID:26209559 PMID:29410032 PMID:30769029 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Cav1 |
caveolin 1 |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of CAV1 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAV1 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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G |
Cav2 |
caveolin 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAV2 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244
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G |
Cavin1 |
caveolae associated protein 1 |
affects expression |
ISO |
Rimonabant affects the expression of CAVIN1 mRNA |
CTD |
PMID:19030233 |
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NCBI chr10:85,884,100...85,896,136
Ensembl chr10:85,889,036...85,896,120
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G |
Ccar1 |
cell division cycle and apoptosis regulator 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CCAR1 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr20:30,685,916...30,728,531
Ensembl chr20:30,685,916...30,728,526
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions decreases expression |
ISO EXP |
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CCL2] Rimonabant results in decreased expression of CCL2 mRNA |
CTD |
PMID:30365523 PMID:32832534 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CCL3] |
CTD |
PMID:32832534 |
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NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccnb1 |
cyclin B1 |
increases expression |
ISO |
Rimonabant results in increased expression of CCNB1 protein |
CTD |
PMID:19479993 |
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NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnd1 |
cyclin D1 |
decreases expression |
ISO |
Rimonabant results in decreased expression of CCND1 protein |
CTD |
PMID:16822929 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccnd2 |
cyclin D2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of CCND2 protein] |
CTD |
PMID:26967640 |
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NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
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G |
Ccng1 |
cyclin G1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CCNG1 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
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G |
Ccpg1 |
cell cycle progression 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CCPG1 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430
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G |
Ccr7 |
C-C motif chemokine receptor 7 |
multiple interactions |
ISO |
[Rimonabant co-treated with MIR762 mRNA] affects the expression of CCR7 mRNA |
CTD |
PMID:30910812 |
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NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
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G |
Cd36 |
CD36 molecule |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of CD36 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CD36 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cdc73 |
cell division cycle 73 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CDC73 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656
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G |
Cdk5 |
cyclin-dependent kinase 5 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [[Ethanol results in increased activity of CDK5 protein] which results in increased degradation of CDK5R1 protein]; Rimonabant inhibits the reaction [Ethanol results in increased activity of CDK5 protein] |
CTD |
PMID:30143782 |
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NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
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G |
Cdk5r1 |
cyclin-dependent kinase 5 regulatory subunit 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [[Ethanol results in increased activity of CDK5 protein] which results in increased degradation of CDK5R1 protein] |
CTD |
PMID:30143782 |
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NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
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G |
Cdkl2 |
cyclin dependent kinase like 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CDKL2 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr14:16,027,381...16,063,257
Ensembl chr14:16,028,363...16,063,252
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
increases expression |
ISO |
Rimonabant results in increased expression of CDKN1B protein |
CTD |
PMID:16822929 |
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NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [butylparaben results in increased expression of CEBPA mRNA] |
CTD |
PMID:27659731 |
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NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Cebpd |
CCAAT/enhancer binding protein delta |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of CEBPD mRNA] |
CTD |
PMID:19030233 |
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NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
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G |
Chd9 |
chromodomain helicase DNA binding protein 9 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CHD9 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr19:15,941,535...16,146,220
Ensembl chr19:15,942,687...16,164,556
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G |
Chek1 |
checkpoint kinase 1 |
decreases phosphorylation |
ISO |
Rimonabant results in decreased phosphorylation of CHEK1 protein |
CTD |
PMID:19479993 |
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NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
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G |
Clic4 |
chloride intracellular channel 4 |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of CLIC4 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CLIC4 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 5:147,456,819...147,513,278
Ensembl chr 5:147,453,712...147,513,452
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G |
Cltc |
clathrin heavy chain |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CLTC mRNA] |
CTD |
PMID:19030233 |
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NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
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G |
Cnot1 |
CCR4-NOT transcription complex, subunit 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CNOT1 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr19:9,255,190...9,346,574
Ensembl chr19:9,255,194...9,346,574
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G |
Cnp |
2',3'-cyclic nucleotide 3' phosphodiesterase |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dronabinol results in increased expression of CNP protein] |
CTD |
PMID:32956517 |
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NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
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G |
Cnr1 |
cannabinoid receptor 1 |
multiple interactions decreases activity affects localization affects binding decreases expression |
ISO EXP |
1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea analog inhibits the reaction [Rimonabant binds to CNR1 protein]; 1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea inhibits the reaction [Rimonabant binds to CNR1 protein]; 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Rimonabant binds to CNR1 protein]; 5F-CUMYL-PICA inhibits the reaction [Rimonabant binds to CNR1 protein]; AM 6527 inhibits the reaction [Rimonabant binds to CNR1 protein]; arachidonyl dopamine inhibits the reaction [Rimonabant binds to CNR1 protein]; Dronabinol inhibits the reaction [Rimonabant binds to CNR1 protein]; methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-methylbutanoate analog inhibits the reaction [Rimonabant binds to CNR1 protein]; methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-methylbutanoate inhibits the reaction [Rimonabant binds to CNR1 protein]; N'-((3Z)-1-(1-hexyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene)benzohydrazide affects the reaction [Rimonabant binds to CNR1 protein]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide inhibits the reaction [Rimonabant binds to CNR1 protein]; Rimonabant binds to and results in decreased activity of CNR1 protein; Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased activity of CNR1]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR1 protein]]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole results in increased activity of CNR1 protein]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] which results in increased abundance of Cyclic AMP]; Rimonabant inhibits the reaction [anandamide results in increased activity of CNR1]; Rimonabant inhibits the reaction [Dronabinol results in increased expression of CNR1 mRNA]; Rimonabant inhibits the reaction [HU 211 results in increased activity of CNR1] Rimonabant results in decreased activity of CNR1 protein Rimonabant affects the localization of CNR1 protein Rimonabant results in decreased expression of CNR1 mRNA [Rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone; [Rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to palmidrol analog; Cannabidiol inhibits the reaction [Poly I-C inhibits the reaction [Rimonabant binds to CNR1 protein]]; Poly I-C inhibits the reaction [Rimonabant binds to CNR1 protein]; Rimonabant binds to and results in decreased activity of CNR1 protein; Rimonabant inhibits the reaction [1-(5-fluoropentyl)-3-(1-naphthoyl)indole analog binds to CNR1 protein]; Rimonabant inhibits the reaction [1-(5-fluoropentyl)-3-(1-naphthoyl)indole binds to CNR1 protein]; Rimonabant inhibits the reaction [[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [IFNG protein affects the reaction [Lipopolysaccharides results in increased abundance of Nitric Oxide]]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] which results in decreased abundance of Nitric Oxide]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of CNR1 protein] 6-methyl-3-(2-nitro-1-(thiophen-2-yl)propyl)-2-phenyl-1H-indole inhibits the reaction [Rimonabant binds to CNR1 protein]; [Rimonabant binds to and results in decreased activity of CNR1 protein] which affects the expression of FOS protein; [Rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to Nicotine; Rimonabant binds to and results in decreased activity of CNR1 protein; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CNR1 mRNA]; Rimonabant inhibits the reaction [5F-ADB cannabinoid binds to and results in increased activity of CNR1 protein]; Rimonabant inhibits the reaction [5F-ADB cannabinoid metabolite binds to and results in increased activity of CNR1 protein]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased transport of Nitric Oxide]]; Rimonabant inhibits the reaction [[anandamide binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased transport of Nitric Oxide]]; Rimonabant inhibits the reaction [HU 211 binds to and results in increased activity of CNR1 protein] |
CTD |
PMID:10027878 PMID:10422789 PMID:10871313 PMID:11517236 PMID:11558437 PMID:11727767 PMID:11730719 PMID:11891798 PMID:12421626 PMID:12509806 PMID:12560108 PMID:15280883 PMID:16113085 PMID:16148442 PMID:16416159 PMID:16554168 PMID:16822929 PMID:17018694 PMID:17558434 PMID:17572696 PMID:18536748 PMID:20107430 PMID:20110567 PMID:20522703 PMID:21702498 PMID:26052038 PMID:26397760 PMID:26398720 PMID:26558620 PMID:27307500 PMID:27513693 PMID:27779402 PMID:29230395 PMID:29410032 PMID:29549157 PMID:30322873 PMID:31202911 PMID:32832534 PMID:35201352 More...
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NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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G |
Cnr2 |
cannabinoid receptor 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR2 protein]]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole results in increased activity of CNR2 protein] |
CTD |
PMID:27779402 |
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NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
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G |
Col1a1 |
collagen type I alpha 1 chain |
decreases expression |
EXP |
Rimonabant results in decreased expression of COL1A1 mRNA |
CTD |
PMID:21863215 PMID:30365523 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Copg2 |
COPI coat complex subunit gamma 2 |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of COPG2 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of COPG2 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 4:59,366,086...59,501,591
Ensembl chr 4:59,366,086...59,501,618
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
increases expression |
EXP |
Rimonabant results in increased expression of CPT1A mRNA |
CTD |
PMID:30365523 |
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NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions |
EXP ISO |
Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of CREB1 protein] Rimonabant inhibits the reaction [Dronabinol results in decreased expression of and results in decreased phosphorylation of CREB1 protein] |
CTD |
PMID:15913574 PMID:19912468 |
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NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Creb3l2 |
cAMP responsive element binding protein 3-like 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CREB3L2 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 4:65,907,570...66,112,078
Ensembl chr 4:65,907,655...66,023,763
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G |
Crh |
corticotropin releasing hormone |
decreases expression multiple interactions |
EXP |
Rimonabant results in decreased expression of CRH mRNA Dronabinol affects the reaction [Rimonabant results in decreased expression of CRH mRNA]; Rimonabant inhibits the reaction [HU 211 results in decreased expression of CRH mRNA] |
CTD |
PMID:12968131 PMID:15099659 |
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NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
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G |
Csde1 |
cold shock domain containing E1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CSDE1 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 2:190,546,015...190,582,790
Ensembl chr 2:190,554,980...190,582,784
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G |
Cul1 |
cullin 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CUL1 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980
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G |
Cul3 |
cullin 3 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CUL3 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462
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G |
Cxadr |
CXADR, Ig-like cell adhesion molecule |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CXADR mRNA] |
CTD |
PMID:19030233 |
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NCBI chr11:16,982,752...17,030,078
Ensembl chr11:16,982,860...17,030,046
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CXCL10] |
CTD |
PMID:32832534 |
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NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CXCL1] |
CTD |
PMID:32832534 |
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NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
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G |
Cyp4v3 |
cytochrome P450, family 4, subfamily v, polypeptide 3 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CYP4V3 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr16:46,917,929...46,958,735
Ensembl chr16:46,918,401...46,943,395
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions |
ISO |
[Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of DDIT3 mRNA] |
CTD |
PMID:31054322 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddx27 |
DEAD-box helicase 27 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of DDX27 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 3:155,744,182...155,763,380
Ensembl chr 3:155,744,150...155,763,372
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G |
Ddx3x |
DEAD-box helicase 3, X-linked |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DDX3X mRNA] |
CTD |
PMID:19030233 |
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NCBI chr X:9,479,532...9,493,455
Ensembl chr X:9,479,532...9,493,168
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G |
Dnajc10 |
DnaJ heat shock protein family (Hsp40) member C10 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DNAJC10 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
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G |
Dpp4 |
dipeptidylpeptidase 4 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DPP4 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 3:46,962,243...47,043,870
Ensembl chr 3:46,962,243...47,043,901
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G |
Dr1 |
down-regulator of transcription 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DR1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638
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G |
Dync1i2 |
dynein cytoplasmic 1 intermediate chain 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DYNC1I2 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 3:56,033,882...56,085,080
Ensembl chr 3:56,033,917...56,085,080
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G |
Edem1 |
ER degradation enhancing alpha-mannosidase like protein 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EDEM1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
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G |
Efna5 |
ephrin A5 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EFNA5 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 9:102,316,753...102,595,480
Ensembl chr 9:102,320,295...102,597,413
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G |
Ehmt2 |
euchromatic histone lysine methyltransferase 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Ethanol promotes the reaction [EHMT2 protein binds to RAC1 promoter]] |
CTD |
PMID:30143782 |
|
NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
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G |
Eif4g2 |
eukaryotic translation initiation factor 4, gamma 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EIF4G2 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 1:165,181,433...165,193,583
Ensembl chr 1:165,181,434...165,193,588
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G |
Eif5 |
eukaryotic translation initiation factor 5 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EIF5 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 6:130,589,200...130,597,656
Ensembl chr 6:130,589,143...130,597,656
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G |
Ell2 |
elongation factor for RNA polymerase II 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ELL2 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781
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G |
Eps15 |
epidermal growth factor receptor pathway substrate 15 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EPS15 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221
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G |
Ermp1 |
endoplasmic reticulum metallopeptidase 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ERMP1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 1:227,383,992...227,422,120
Ensembl chr 1:227,387,920...227,436,909
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G |
Faah |
fatty acid amide hydrolase |
multiple interactions |
EXP ISO |
[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Rimonabant] affects the expression of FAAH mRNA FAAH affects the reaction [Rimonabant affects the expression of CARTPT protein]; Rimonabant inhibits the reaction [FAAH gene mutant form results in increased susceptibility to anandamide] |
CTD |
PMID:16131814 PMID:27385208 PMID:32833042 |
|
NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
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G |
Fam199x |
family with sequence similarity 199, X-linked |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FAM199X mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr X:100,384,502...100,413,150
Ensembl chr X:100,384,225...100,414,938
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G |
Far1 |
fatty acyl CoA reductase 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FAR1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 1:167,644,622...167,705,868
Ensembl chr 1:167,644,677...167,705,730
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G |
Fasn |
fatty acid synthase |
decreases expression multiple interactions |
ISO |
Rimonabant results in decreased expression of FASN mRNA Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of FASN mRNA] |
CTD |
PMID:19030233 PMID:20110567 |
|
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Fbxl5 |
F-box and leucine-rich repeat protein 5 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FBXL5 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr14:67,305,109...67,347,383
Ensembl chr14:67,267,801...67,347,383
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G |
Fbxw7 |
F-box and WD repeat domain containing 7 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of FBXW7 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941
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G |
Fem1a |
fem-1 homolog A |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of FEM1A mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 9:1,091,695...1,093,901
Ensembl chr 9:1,090,527...1,100,628
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G |
Fermt2 |
FERM domain containing kindlin 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FERMT2 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811
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G |
Fgf1 |
fibroblast growth factor 1 |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FGF1 mRNA] Rimonabant affects the expression of FGF1 mRNA |
CTD |
PMID:19030233 |
|
NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
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G |
Fmr1 |
fragile X messenger ribonucleoprotein 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FMR1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr X:147,240,239...147,278,057
Ensembl chr X:147,240,301...147,278,050
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G |
Fndc3b |
fibronectin type III domain containing 3B |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FNDC3B mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
EXP ISO |
Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOS protein] [Rimonabant binds to and results in decreased activity of CNR1 protein] which affects the expression of FOS protein; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of FOS protein] |
CTD |
PMID:9751146 PMID:12560108 PMID:15280883 |
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Fosb |
FosB proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
EXP |
Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOSB protein] |
CTD |
PMID:9751146 |
|
NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
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G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
multiple interactions |
EXP |
Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOSL1 protein] |
CTD |
PMID:9751146 |
|
NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
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G |
Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
multiple interactions |
EXP |
Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOSL2 protein] |
CTD |
PMID:9751146 |
|
NCBI chr 6:24,297,898...24,319,157
Ensembl chr 6:24,300,956...24,320,034
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G |
Frmd4b |
FERM domain containing 4B |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FRMD4B mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 4:129,895,401...130,222,070
Ensembl chr 4:129,895,708...130,084,197
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G |
G6pc3 |
glucose 6 phosphatase catalytic subunit 3 |
increases expression |
ISO |
Rimonabant results in increased expression of G6PC3 mRNA |
CTD |
PMID:20110567 |
|
NCBI chr10:87,146,987...87,151,223
Ensembl chr10:87,146,901...87,151,221
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G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
increases expression |
ISO |
Rimonabant results in increased expression of GAPDH mRNA |
CTD |
PMID:16282221 |
|
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
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G |
Gfap |
glial fibrillary acidic protein |
decreases expression multiple interactions |
ISO |
Rimonabant results in decreased expression of GFAP protein Rimonabant inhibits the reaction [Dronabinol results in increased expression of GFAP mRNA] |
CTD |
PMID:21373835 PMID:36529297 |
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NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
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G |
Ggps1 |
geranylgeranyl diphosphate synthase 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GGPS1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr17:51,263,262...51,282,471
Ensembl chr17:51,263,263...51,276,220
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G |
Gls |
glutaminase |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GLS mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
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G |
Gmfb |
glia maturation factor, beta |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GMFB mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331
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|
G |
Gpld1 |
glycosylphosphatidylinositol specific phospholipase D1 |
decreases expression |
ISO |
Rimonabant results in decreased expression of GPLD1 mRNA |
CTD |
PMID:20110567 |
|
NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
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G |
Gpr55 |
G protein-coupled receptor 55 |
multiple interactions |
ISO |
Rimonabant binds to and results in increased activity of GPR55 protein |
CTD |
PMID:17876302 |
|
NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613
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G |
Gpt |
glutamic--pyruvic transaminase |
decreases expression |
EXP ISO |
Rimonabant results in decreased expression of GPT protein |
CTD |
PMID:28705172 PMID:30365523 |
|
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Grb14 |
growth factor receptor bound protein 14 |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of GRB14 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GRB14 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889
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G |
Gria1 |
glutamate ionotropic receptor AMPA type subunit 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIA1] Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIA1 mRNA] |
CTD |
PMID:19912468 PMID:29230395 |
|
NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
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G |
Grin2a |
glutamate ionotropic receptor NMDA type subunit 2A |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIN2A] |
CTD |
PMID:19912468 |
|
NCBI chr10:5,630,684...6,043,341
Ensembl chr10:5,631,369...6,044,637
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G |
Grin2b |
glutamate ionotropic receptor NMDA type subunit 2B |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIN2B] |
CTD |
PMID:19912468 |
|
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
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G |
Gsta1 |
glutathione S-transferase alpha 1 |
increases expression |
EXP |
Rimonabant results in increased expression of GSTA1 mRNA |
CTD |
PMID:30365523 |
|
NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
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|
G |
Hdhd2 |
haloacid dehalogenase-like hydrolase domain containing 2 |
affects expression |
ISO |
Rimonabant affects the expression of HDHD2 mRNA |
CTD |
PMID:19030233 |
|
NCBI chr18:70,475,037...70,526,471
Ensembl chr18:70,474,926...70,526,470
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of HIF1A mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hipk3 |
homeodomain interacting protein kinase 3 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of HIPK3 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 3:90,796,980...90,866,701
Ensembl chr 3:90,800,296...90,867,759
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G |
Hmox1 |
heme oxygenase 1 |
increases expression |
EXP |
Rimonabant results in increased expression of HMOX1 mRNA; Rimonabant results in increased expression of HMOX1 protein |
CTD |
PMID:30365523 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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|
G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
decreases activity |
ISO |
Rimonabant results in decreased activity of HNF4A protein |
CTD |
PMID:31981244 |
|
NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
|
|
G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of HSP90AA1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
|
|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
ISO |
[Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of HSPA5 mRNA] |
CTD |
PMID:31054322 |
|
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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|
G |
Hycc2 |
hyccin PI4KA lipid kinase complex subunit 2 |
affects expression |
ISO |
Rimonabant affects the expression of HYCC2 mRNA |
CTD |
PMID:19030233 |
|
NCBI chr 9:60,056,883...60,129,176
Ensembl chr 9:60,056,890...60,093,007
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|
G |
Icam1 |
intercellular adhesion molecule 1 |
decreases expression multiple interactions |
ISO |
Rimonabant results in decreased expression of ICAM1 protein Rimonabant inhibits the reaction [Glucose results in increased expression of ICAM1 protein] |
CTD |
PMID:21373835 |
|
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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|
G |
Ifng |
interferon gamma |
multiple interactions |
EXP |
Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [IFNG protein affects the reaction [Lipopolysaccharides results in increased abundance of Nitric Oxide]]]; Rimonabant inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein co-treated with (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone] results in decreased expression of NOS2 mRNA]; Rimonabant inhibits the reaction [Cannabinol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide]] |
CTD |
PMID:11520904 PMID:11727767 |
|
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
|
|
G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IGF1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
|
|
G |
Igfbp5 |
insulin-like growth factor binding protein 5 |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of IGFBP5 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IGFBP5 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
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|
G |
Il10 |
interleukin 10 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dronabinol promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL10 protein]] |
CTD |
PMID:32385136 |
|
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
|
|
G |
Il12rb2 |
interleukin 12 receptor subunit beta 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dronabinol results in decreased expression of IL12RB2 mRNA] |
CTD |
PMID:14741435 PMID:18792785 |
|
NCBI chr 4:96,424,615...96,515,327
Ensembl chr 4:96,426,842...96,515,289
|
|
G |
Il18 |
interleukin 18 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of IL18 protein] |
CTD |
PMID:27932991 |
|
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
[Rimonabant co-treated with SR 144528] inhibits the reaction [OMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of IL1B]; Rimonabant inhibits the reaction [OMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; Rimonabant promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] |
CTD |
PMID:15748152 PMID:32832534 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
|
|
G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of IL6] |
CTD |
PMID:32832534 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
|
|
G |
Ins1 |
insulin 1 |
multiple interactions decreases expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of INS1 protein]; Rimonabant inhibits the reaction [Dietary Fats results in increased secretion of INS1 protein]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of INS1 protein] Rimonabant results in decreased expression of INS1 protein |
CTD |
PMID:19030233 PMID:26563389 PMID:26967640 PMID:30910812 |
|
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
|
|
G |
Ins2 |
insulin 2 |
decreases expression |
ISO |
Rimonabant results in decreased expression of INS protein |
CTD |
PMID:20110567 |
|
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
|
|
G |
Iqgap1 |
IQ motif containing GTPase activating protein 1 |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IQGAP1 mRNA] Rimonabant affects the expression of IQGAP1 mRNA |
CTD |
PMID:19030233 |
|
NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
|
|
G |
Irf5 |
interferon regulatory factor 5 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of IRF5] |
CTD |
PMID:32832534 |
|
NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267
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G |
Itgam |
integrin subunit alpha M |
decreases expression |
EXP |
Rimonabant results in decreased expression of ITGAM mRNA |
CTD |
PMID:30365523 |
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NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
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G |
Itgav |
integrin subunit alpha V |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ITGAV mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 3:68,838,524...68,926,653
Ensembl chr 3:68,838,189...68,926,639
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G |
Itgb1 |
integrin subunit beta 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ITGB1 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
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G |
Itpr2 |
inositol 1,4,5-trisphosphate receptor, type 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ITPR2 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164
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G |
Ivns1abp |
influenza virus NS1A binding protein |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IVNS1ABP mRNA] |
CTD |
PMID:19030233 |
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NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
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G |
Kif5b |
kinesin family member 5B |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KIF5B mRNA] |
CTD |
PMID:19030233 |
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NCBI chr17:51,489,873...51,527,508
Ensembl chr17:51,489,944...51,527,508
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G |
Klf4 |
KLF transcription factor 4 |
increases expression multiple interactions |
ISO |
Rimonabant results in increased expression of KLF4 mRNA MIR466J mRNA affects the reaction [Rimonabant results in increased expression of KLF4 mRNA]; Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of KLF4 mRNA] |
CTD |
PMID:30910812 |
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NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
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G |
Klf6 |
KLF transcription factor 6 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KLF6 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
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G |
Klhl9 |
kelch-like family member 9 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KLHL9 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 5:103,333,747...103,337,931
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G |
Kpna3 |
karyopherin subunit alpha 3 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KPNA3 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr15:35,536,310...35,610,066
Ensembl chr15:35,536,316...35,610,419
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G |
Kpnb1 |
karyopherin subunit beta 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KPNB1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
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G |
Lamp2 |
lysosomal-associated membrane protein 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LAMP2 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522
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G |
Large1 |
LARGE xylosyl- and glucuronyltransferase 1 |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LARGE1 mRNA] Rimonabant affects the expression of LARGE1 mRNA |
CTD |
PMID:19030233 |
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NCBI chr19:11,603,129...12,048,930
Ensembl chr19:11,603,129...12,048,930
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G |
Lep |
leptin |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased secretion of LEP protein]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of BCL2 protein]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of CCND2 protein]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of INS1 protein] |
CTD |
PMID:19030233 PMID:26967640 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lhb |
luteinizing hormone subunit beta |
multiple interactions |
EXP |
Rimonabant inhibits the reaction [Dronabinol results in decreased expression of LHB protein] |
CTD |
PMID:9825732 |
|
NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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G |
Lipc |
lipase C, hepatic type |
increases expression |
ISO |
Rimonabant results in increased expression of LIPC mRNA |
CTD |
PMID:20110567 |
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NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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G |
Lipe |
lipase E, hormone sensitive type |
affects expression |
ISO |
Rimonabant affects the expression of LIPE mRNA |
CTD |
PMID:20110567 |
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NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
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G |
Lmo1 |
LIM domain only 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LMO1 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 1:163,132,338...163,168,521
Ensembl chr 1:163,132,339...163,168,522
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G |
Lpgat1 |
lysophosphatidylglycerol acyltransferase 1 |
affects expression |
ISO |
Rimonabant affects the expression of LPGAT1 mRNA |
CTD |
PMID:19030233 |
|
NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333
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G |
Lrrfip1 |
LRR binding FLII interacting protein 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LRRFIP1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 9:91,592,032...91,720,250
Ensembl chr 9:91,643,197...91,720,250
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G |
Mag |
myelin-associated glycoprotein |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dronabinol results in increased expression of MAG protein] |
CTD |
PMID:32956517 |
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NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions |
ISO |
Rimonabant results in increased expression of and results in increased lipidation of MAP1LC3B protein |
CTD |
PMID:31570772 |
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NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions affects localization decreases activity |
ISO EXP |
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [delta(9)-tetrahydrocannabinolic acid results in increased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [methanandamide results in increased phosphorylation of MAPK1 protein] Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in decreased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein] Rimonabant affects the localization of MAPK1 protein Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of MAPK1 protein] Rimonabant results in decreased activity of MAPK1 protein |
CTD |
PMID:8526880 PMID:11553284 PMID:12657697 PMID:12834810 PMID:16282221 PMID:16822929 PMID:18950629 PMID:31917333 PMID:32510591 More...
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions decreases activity affects localization |
ISO EXP |
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of MAPK3 protein] Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in decreased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein] Rimonabant results in decreased activity of MAPK3 protein Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [delta(9)-tetrahydrocannabinolic acid results in increased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [methanandamide results in increased phosphorylation of MAPK3 protein] Rimonabant affects the localization of MAPK3 protein |
CTD |
PMID:8526880 PMID:11553284 PMID:12657697 PMID:12834810 PMID:16282221 PMID:16822929 PMID:18950629 PMID:31917333 PMID:32510591 More...
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK8 protein]; Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of MAPK8 protein] |
CTD |
PMID:18950629 |
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NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Marchf6 |
membrane associated ring-CH-type finger 6 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MARCHF6 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 2:82,455,686...82,532,917
Ensembl chr 2:82,455,689...82,532,910
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G |
Mbnl1 |
muscleblind-like splicing regulator 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MBNL1 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 2:144,639,819...144,814,395
Ensembl chr 2:144,670,285...144,814,368
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G |
Mbnl2 |
muscleblind-like splicing regulator 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MBNL2 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr15:97,385,238...97,542,924
Ensembl chr15:97,385,244...97,542,937
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G |
Mef2c |
myocyte enhancer factor 2C |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dronabinol results in increased expression of MEF2C mRNA] |
CTD |
PMID:36529297 |
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NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
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G |
Mest |
mesoderm specific transcript |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of MEST mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MEST mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 4:59,354,445...59,364,919
Ensembl chr 4:59,354,447...59,366,145
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G |
Mgll |
monoglyceride lipase |
affects response to substance |
ISO |
MGLL protein affects the susceptibility to Rimonabant |
CTD |
PMID:21911610 |
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NCBI chr 4:121,192,187...121,294,187
Ensembl chr 4:121,192,195...121,294,179
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G |
Mir16 |
microRNA 16 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of MIR16 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443
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G |
Mlkl |
mixed lineage kinase domain like pseudokinase |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Quetiapine Fumarate affects the localization of MLKL protein]; Rimonabant inhibits the reaction [Quetiapine Fumarate results in increased expression of and results in increased phosphorylation of MLKL protein] |
CTD |
PMID:31220554 |
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NCBI chr19:39,278,123...39,304,555
Ensembl chr19:39,276,785...39,304,502
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G |
Mmp13 |
matrix metallopeptidase 13 |
decreases expression |
EXP |
Rimonabant results in decreased expression of MMP13 mRNA |
CTD |
PMID:21863215 |
|
NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
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G |
Mog |
myelin oligodendrocyte glycoprotein |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dronabinol results in increased expression of MOG protein] |
CTD |
PMID:32956517 |
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NCBI chr20:1,513,137...1,523,473
Ensembl chr20:1,513,239...1,523,474
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G |
Mospd1 |
motile sperm domain containing 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MOSPD1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr X:133,100,200...133,127,960
Ensembl chr X:133,100,422...133,127,908 Ensembl chr 1:133,100,422...133,127,908
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G |
Mycbp2 |
MYC binding protein 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MYCBP2 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr15:79,937,354...80,175,432
Ensembl chr15:79,937,354...80,175,498
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G |
Nap1l1 |
nucleosome assembly protein 1-like 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NAP1L1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
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G |
Napepld |
N-acyl phosphatidylethanolamine phospholipase D |
multiple interactions |
EXP |
[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Rimonabant] affects the expression of NAPEPLD mRNA |
CTD |
PMID:32833042 |
|
NCBI chr 4:13,360,532...13,398,815
Ensembl chr 4:13,361,006...13,398,748
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G |
Ncl |
nucleolin |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NCL mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136
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G |
Ndc1 |
NDC1 transmembrane nucleoporin |
affects expression |
ISO |
Rimonabant affects the expression of NDC1 mRNA |
CTD |
PMID:19030233 |
|
NCBI chr 5:122,155,992...122,202,295
Ensembl chr 5:122,155,967...122,202,291
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G |
Ndufb11 |
NADH:ubiquinone oxidoreductase subunit B11 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of NDUFB11 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr X:1,572,805...1,575,063
Ensembl chr X:1,572,785...1,575,062
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G |
Ndufb9 |
NADH:ubiquinone oxidoreductase subunit B9 |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of NDUFB9 mRNA] Rimonabant affects the expression of NDUFB9 mRNA |
CTD |
PMID:19030233 |
|
NCBI chr 7:90,481,013...90,487,360
Ensembl chr 7:90,436,621...90,488,009
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G |
Ndufs8 |
NADH:ubiquinone oxidoreductase core subunit S8 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of NDUFS8 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511
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G |
Nedd4 |
NEDD4 E3 ubiquitin protein ligase |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NEDD4 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
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G |
Nek7 |
NIMA-related kinase 7 |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NEK7 mRNA] Rimonabant affects the expression of NEK7 mRNA |
CTD |
PMID:19030233 |
|
NCBI chr13:50,022,212...50,149,374
Ensembl chr13:50,022,218...50,149,296
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G |
Nes |
nestin |
multiple interactions |
ISO |
[Rimonabant co-treated with Dronabinol] results in increased expression of NES mRNA |
CTD |
PMID:36529297 |
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NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
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G |
Nfatc3 |
nuclear factor of activated T-cells 3 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NFATC3 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
increases expression |
EXP |
Rimonabant results in increased expression of NFE2L2 mRNA |
CTD |
PMID:30365523 |
|
NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
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G |
Nid1 |
nidogen 1 |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NID1 mRNA] Rimonabant affects the expression of NID1 mRNA |
CTD |
PMID:19030233 |
|
NCBI chr17:86,085,046...86,158,277
Ensembl chr17:86,085,077...86,158,267
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of NLRP3] Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of NLRP3 protein] |
CTD |
PMID:27932991 PMID:32832534 |
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NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO EXP |
[Rimonabant co-treated with SR 144528] inhibits the reaction [OMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NOS2]; Rimonabant promotes the reaction [PF 3845 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]] Rimonabant inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein co-treated with (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone] results in decreased expression of NOS2 mRNA] |
CTD |
PMID:11520904 PMID:15748152 PMID:30910812 PMID:31121907 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Npr3 |
natriuretic peptide receptor 3 |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NPR3 mRNA] Rimonabant affects the expression of NPR3 mRNA |
CTD |
PMID:19030233 |
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NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression |
EXP |
Rimonabant results in increased expression of NQO1 mRNA; Rimonabant results in increased expression of NQO1 protein |
CTD |
PMID:30365523 |
|
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NR3C1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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G |
Ntn1 |
netrin 1 |
multiple interactions decreases expression |
ISO |
Rimonabant affects the reaction [Dietary Fats affects the expression of NTN1 protein]; Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NTN1 mRNA]; Rimonabant inhibits the reaction [MIR762 mRNA results in increased expression of NTN1 mRNA] Rimonabant results in decreased expression of NTN1 mRNA |
CTD |
PMID:30910812 |
|
NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326
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G |
Opa1 |
OPA1, mitochondrial dynamin like GTPase |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of OPA1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
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|
G |
Osbpl8 |
oxysterol binding protein-like 8 |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of OSBPL8 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of OSBPL8 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 7:46,596,944...46,749,888
Ensembl chr 7:46,596,983...46,749,888
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|
G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
decreases expression |
ISO |
Rimonabant results in decreased expression of PARP1 protein |
CTD |
PMID:19479993 |
|
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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|
G |
Pc |
pyruvate carboxylase |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PCX mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
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|
G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
increases expression |
ISO |
Rimonabant results in increased expression of PCK1 mRNA |
CTD |
PMID:20110567 |
|
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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|
G |
Pcyox1 |
prenylcysteine oxidase 1 |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PCYOX1 mRNA] Rimonabant affects the expression of PCYOX1 mRNA |
CTD |
PMID:19030233 |
|
NCBI chr 4:118,832,114...118,842,951
Ensembl chr 4:118,830,638...118,842,951
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G |
Phip |
pleckstrin homology domain interacting protein |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PHIP mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 8:83,776,802...83,891,192
Ensembl chr 8:83,781,465...83,894,283
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|
G |
Pik3ca |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of PIK3CA mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PIK3CA mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
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|
G |
Plac8 |
placenta associated 8 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PLAC8 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr14:9,052,601...9,074,264
Ensembl chr14:9,063,048...9,074,264
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|
G |
Plekha1 |
pleckstrin homology domain containing A1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PLEKHA1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156
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|
G |
Plin2 |
perilipin 2 |
decreases expression multiple interactions |
ISO |
Rimonabant results in decreased expression of PLIN2 protein Rimonabant inhibits the reaction [Oleic Acid results in increased expression of PLIN2 protein] |
CTD |
PMID:31570772 |
|
NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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|
G |
Pmm1 |
phosphomannomutase 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PMM1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 7:113,466,632...113,477,004
Ensembl chr 7:113,466,632...113,477,022
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|
G |
Pold2 |
DNA polymerase delta 2, accessory subunit |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of POLD2 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr14:80,748,971...80,755,188
Ensembl chr14:80,748,974...80,755,160
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G |
Polr2j |
RNA polymerase II subunit J |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of POLR2J mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr12:20,543,038...20,548,590
Ensembl chr12:20,543,038...20,548,594
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
increases expression |
EXP |
Rimonabant results in increased expression of PPARA mRNA |
CTD |
PMID:30365523 |
|
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
affects expression |
ISO |
Rimonabant affects the expression of PPARG mRNA |
CTD |
PMID:20110567 |
|
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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|
G |
Ppfibp1 |
PPFIA binding protein 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PPFIBP1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 4:179,807,579...179,951,428
Ensembl chr 4:179,808,794...179,951,428
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|
G |
Ppp1cb |
protein phosphatase 1 catalytic subunit beta |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PPP1CB mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824
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G |
Ppp3ca |
protein phosphatase 3 catalytic subunit alpha |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PPP3CA mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
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G |
Prkd3 |
protein kinase D3 |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PRKD3 mRNA] Rimonabant affects the expression of PRKD3 mRNA |
CTD |
PMID:19030233 |
|
NCBI chr 6:16,032,507...16,108,444
Ensembl chr 6:16,032,585...16,108,443
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G |
Prkn |
parkin RBR E3 ubiquitin protein ligase |
decreases response to substance multiple interactions |
ISO EXP |
PRKN results in decreased susceptibility to Rimonabant Rimonabant affects the reaction [PRKN mutant form affects the activity of TH protein] |
CTD |
PMID:15882845 |
|
NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
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G |
Prl |
prolactin |
multiple interactions increases expression |
ISO EXP |
Rimonabant inhibits the reaction [Dronabinol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of PRL mRNA]] Dronabinol affects the reaction [Rimonabant results in increased expression of PRL protein]; Rimonabant inhibits the reaction [Dronabinol results in decreased expression of PRL protein] |
CTD |
PMID:9825732 PMID:15099659 PMID:31154070 |
|
NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
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|
G |
Prpf40a |
pre-mRNA processing factor 40 homolog A |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PRPF40A mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 3:37,625,585...37,689,859
Ensembl chr 3:37,627,690...37,690,886
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|
G |
Prps1 |
phosphoribosyl pyrophosphate synthetase 1 |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of PRPS1 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PRPS1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr X:104,132,139...104,154,191
Ensembl chr X:104,132,141...104,154,187
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G |
Ptbp3 |
polypyrimidine tract binding protein 3 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PTBP3 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 5:74,313,536...74,399,439
Ensembl chr 5:74,315,101...74,399,791
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G |
Pten |
phosphatase and tensin homolog |
affects expression multiple interactions |
EXP |
Rimonabant affects the expression of PTEN mRNA [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Rimonabant] affects the expression of PTEN mRNA |
CTD |
PMID:32833042 |
|
NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
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G |
Ptges2 |
prostaglandin E synthase 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PTGES2 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 3:15,690,501...15,697,688
Ensembl chr 3:15,690,501...15,697,688
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of PTGS2 protein]]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]] |
CTD |
PMID:26209559 PMID:30769029 |
|
NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Ptp4a1 |
protein tyrosine phosphatase 4A1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PTP4A1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964
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G |
Pyy |
peptide YY |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PYY mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr10:87,061,155...87,062,278
Ensembl chr10:87,061,161...87,061,815
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G |
Rac1 |
Rac family small GTPase 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Ethanol promotes the reaction [EHMT2 protein binds to RAC1 promoter]]; Rimonabant inhibits the reaction [Ethanol results in decreased expression of RAC1 protein] |
CTD |
PMID:30143782 |
|
NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
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G |
Raf1 |
Raf-1 proto-oncogene, serine/threonine kinase |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dronabinol results in increased localization of RAF1 protein]; Rimonabant inhibits the reaction [methanandamide results in increased localization of RAF1 protein] |
CTD |
PMID:12834810 |
|
NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
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G |
Ramp2 |
receptor activity modifying protein 2 |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of RAMP2 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RAMP2 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829
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G |
Rbms1 |
RNA binding motif, single stranded interacting protein 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RBMS1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 3:45,195,828...45,420,406
Ensembl chr 3:45,197,972...45,420,376
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G |
Rbpj |
recombination signal binding protein for immunoglobulin kappa J region |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RBPJ mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions decreases expression |
ISO |
Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] Rimonabant results in decreased expression of RELA protein |
CTD |
PMID:21373835 PMID:26209559 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Rfng |
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RFNG mRNA] Rimonabant affects the expression of RFNG mRNA |
CTD |
PMID:19030233 |
|
NCBI chr10:106,047,221...106,050,331
Ensembl chr10:106,047,221...106,050,345
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G |
Rgs11 |
regulator of G-protein signaling 11 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RGS11 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr10:15,222,803...15,231,060
Ensembl chr10:15,222,803...15,231,060
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G |
Ripk1 |
receptor interacting serine/threonine kinase 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Quetiapine Fumarate results in increased expression of RIPK1 protein] |
CTD |
PMID:31220554 |
|
NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
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G |
Ripk3 |
receptor-interacting serine-threonine kinase 3 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Quetiapine Fumarate results in increased expression of RIPK3 protein] |
CTD |
PMID:31220554 |
|
NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
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G |
rnf141 |
ring finger protein 141 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF141 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 1:164,933,972...164,957,081
Ensembl chr 1:164,931,077...164,957,118
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G |
Rnf185 |
ring finger protein 185 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RNF185 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr14:78,292,517...78,329,832
Ensembl chr14:78,292,516...78,329,864
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G |
Rnf19a |
ring finger protein 19A, RBR E3 ubiquitin protein ligase |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF19A mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 7:67,425,833...67,465,214
Ensembl chr 7:67,425,837...67,465,222
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G |
Rnf2 |
ring finger protein 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF2 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr13:63,553,964...63,584,047
Ensembl chr13:63,554,862...63,583,099
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G |
Rnf6 |
ring finger protein 6 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF6 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr12:8,816,777...8,826,870
Ensembl chr12:8,816,833...8,826,847
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G |
Rp9 |
RP9, pre-mRNA splicing factor |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RP9 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 8:20,955,447...21,005,225
Ensembl chr 8:20,941,362...21,005,175
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G |
Rpf2 |
ribosome production factor 2 homolog |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPF2 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr20:43,630,003...43,651,477
Ensembl chr20:43,629,951...43,651,509
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G |
Rpl18 |
ribosomal protein L18 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPL18 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 1:96,188,811...96,191,452
Ensembl chr 1:96,188,112...96,191,452
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G |
Rpl28 |
ribosomal protein L28 |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of RPL28 mRNA Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPL28 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 1:69,052,148...69,054,735
Ensembl chr 1:69,053,203...69,055,032
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G |
Rpl41 |
ribosomal protein L41 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPL41 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 7:977,885...978,965
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G |
Rps10 |
ribosomal protein S10 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPS10 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr20:5,694,313...5,698,922
Ensembl chr20:5,694,313...5,699,044
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G |
Rps15 |
ribosomal protein S15 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPS15 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 7:9,416,003...9,417,442
Ensembl chr 7:9,416,004...9,417,450
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G |
Rps28 |
ribosomal protein S28 |
affects expression |
ISO |
Rimonabant affects the expression of RPS28 mRNA |
CTD |
PMID:19030233 |
|
NCBI chr 7:14,607,801...14,609,170
Ensembl chr 7:14,607,801...14,609,170
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G |
Rps6 |
ribosomal protein S6 |
decreases phosphorylation |
ISO |
Rimonabant results in decreased phosphorylation of RPS6 protein |
CTD |
PMID:30687088 |
|
NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
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G |
Rps8 |
ribosomal protein S8 |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of RPS8 mRNA Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPS8 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268
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G |
Rras2 |
RAS related 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RRAS2 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111
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G |
Rxrb |
retinoid X receptor beta |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RXRB mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
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G |
Ryk |
receptor-like tyrosine kinase |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of RYK mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RYK mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 8:103,419,348...103,492,083
Ensembl chr 8:103,419,275...103,491,698
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G |
Scarb1 |
scavenger receptor class B, member 1 |
increases expression |
ISO |
Rimonabant results in increased expression of SCARB1 mRNA |
CTD |
PMID:20110567 |
|
NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
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G |
Scd |
stearoyl-CoA desaturase |
decreases expression |
ISO |
Rimonabant results in decreased expression of SCD1 mRNA |
CTD |
PMID:20110567 |
|
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Scd2 |
stearoyl-Coenzyme A desaturase 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SCD2 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232
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G |
Scoc |
short coiled-coil protein |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SCOC mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr19:24,659,651...24,689,236
Ensembl chr19:24,659,651...24,693,217
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|
G |
Sec62 |
SEC62 homolog, preprotein translocation factor |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEC62 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 2:112,570,810...112,607,576
Ensembl chr 2:112,570,819...112,601,814
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G |
Sec63 |
SEC63 homolog, protein translocation regulator |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEC63 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055
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G |
Sema3c |
semaphorin 3C |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEMA3C mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 4:17,583,212...17,747,234
Ensembl chr 4:17,583,212...17,746,534
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G |
Sepsecs |
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase |
affects expression |
ISO |
Rimonabant affects the expression of SEPSECS mRNA |
CTD |
PMID:19030233 |
|
NCBI chr14:58,311,484...58,341,745
Ensembl chr14:58,311,499...58,341,740
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G |
Septin2 |
septin 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEPTIN2 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 9:94,018,141...94,051,386
Ensembl chr 9:94,018,208...94,051,386
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G |
Septin6 |
septin 6 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SEPTIN6 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr X:116,153,255...116,230,334
Ensembl chr X:116,153,255...116,230,115
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G |
Serpinb6a |
serpin family B member 6A |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SERPINB6A mRNA] Rimonabant affects the expression of SERPINB6A mRNA |
CTD |
PMID:19030233 |
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NCBI chr17:30,871,428...30,989,703
Ensembl chr17:30,871,468...31,014,427
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G |
Serpine1 |
serpin family E member 1 |
decreases expression |
EXP |
Rimonabant results in decreased expression of SERPINE1 protein |
CTD |
PMID:17882151 |
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NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Sestd1 |
SEC14 and spectrin domain containing 1 |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SESTD1 mRNA] Rimonabant affects the expression of SESTD1 mRNA |
CTD |
PMID:19030233 |
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NCBI chr 3:62,123,590...62,220,759
Ensembl chr 3:62,129,887...62,220,546
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G |
Sgta |
small glutamine rich tetratricopeptide repeat co-chaperone alpha |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SGTA mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458
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G |
Sh3bgrl1 |
SH3 domain binding glutamate rich protein like 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SH3BGRL mRNA] |
CTD |
PMID:19030233 |
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NCBI chr X:74,167,029...74,263,783
Ensembl chr X:74,166,871...74,263,783
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G |
Sipa1l1 |
signal-induced proliferation-associated 1 like 1 |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SIPA1L1 mRNA] Rimonabant affects the expression of SIPA1L1 mRNA |
CTD |
PMID:19030233 |
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NCBI chr 6:101,839,351...102,118,408
Ensembl chr 6:101,839,404...102,116,950
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G |
Slc2a4 |
solute carrier family 2 member 4 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SLC2A4 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
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G |
Slc39a10 |
solute carrier family 39 member 10 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SLC39A10 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325
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G |
Slc39a8 |
solute carrier family 39 member 8 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SLC39A8 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129
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G |
Smarca2 |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SMARCA2 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 1:224,191,125...224,358,640
Ensembl chr 1:224,191,125...224,358,684
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G |
Socs1 |
suppressor of cytokine signaling 1 |
decreases expression |
EXP |
Rimonabant results in decreased expression of SOCS1 mRNA |
CTD |
PMID:30365523 |
|
NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
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G |
Socs3 |
suppressor of cytokine signaling 3 |
decreases expression |
EXP |
Rimonabant results in decreased expression of SOCS3 mRNA |
CTD |
PMID:30365523 |
|
NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
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G |
Sorbs2 |
sorbin and SH3 domain containing 2 |
affects expression |
ISO |
Rimonabant affects the expression of SORBS2 mRNA |
CTD |
PMID:19030233 |
|
NCBI chr16:46,435,220...46,748,743
Ensembl chr16:46,435,237...46,626,514
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G |
Sparc |
secreted protein acidic and cysteine rich |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SPARC mRNA] Rimonabant affects the expression of SPARC mRNA |
CTD |
PMID:19030233 |
|
NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
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G |
Sptbn1 |
spectrin, beta, non-erythrocytic 1 |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SPTBN1 mRNA] Rimonabant affects the expression of SPTBN1 mRNA |
CTD |
PMID:19030233 |
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NCBI chr14:103,842,684...104,008,507
Ensembl chr14:103,842,684...104,008,507
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G |
Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of SRC protein] |
CTD |
PMID:16046413 |
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NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
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G |
Srp72 |
signal recognition particle 72 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SRP72 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr14:31,168,175...31,195,717
Ensembl chr14:31,168,293...31,195,729
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G |
St3gal6 |
ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ST3GAL6 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr11:42,061,282...42,121,801
Ensembl chr11:42,077,621...42,121,776
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G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of STAT3 protein] |
CTD |
PMID:16046413 |
|
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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G |
Stat6 |
signal transducer and activator of transcription 6 |
multiple interactions |
ISO |
[MIR466J mRNA co-treated with Rimonabant] affects the expression of STAT6 mRNA; Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of STAT6 mRNA] |
CTD |
PMID:30910812 |
|
NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
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G |
Stim2 |
stromal interaction molecule 2 |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of STIM2 mRNA] Rimonabant affects the expression of STIM2 mRNA |
CTD |
PMID:19030233 |
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NCBI chr14:56,878,428...57,004,405
Ensembl chr14:56,878,645...57,004,179
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G |
Strn4 |
striatin 4 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of STRN4 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 1:77,482,267...77,511,862
Ensembl chr 1:77,482,094...77,511,858
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G |
Tcea1 |
transcription elongation factor A1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of TCEA1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 5:14,631,454...14,668,769
Ensembl chr 5:14,631,454...14,668,745
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G |
Tgfb1 |
transforming growth factor, beta 1 |
decreases expression |
EXP |
Rimonabant results in decreased expression of TGFB1 mRNA |
CTD |
PMID:30365523 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tgif2 |
TGFB-induced factor homeobox 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TGIF2 mRNA] |
CTD |
PMID:19030233 |
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NCBI chr 3:145,333,152...145,348,599
Ensembl chr 3:145,333,418...145,348,596
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G |
Th |
tyrosine hydroxylase |
multiple interactions increases activity |
EXP |
Rimonabant affects the reaction [PRKN mutant form affects the activity of TH protein]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of TH protein] Rimonabant results in increased activity of TH protein |
CTD |
PMID:9188039 PMID:10700552 PMID:15882845 |
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NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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G |
Thy1 |
Thy-1 cell surface antigen |
multiple interactions |
EXP |
Rimonabant inhibits the reaction [methanandamide affects the expression of THY1 mRNA] |
CTD |
PMID:17591864 |
|
NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
decreases expression |
EXP |
Rimonabant results in decreased expression of TIMP1 mRNA |
CTD |
PMID:21863215 PMID:30365523 |
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NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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G |
Tmed7 |
transmembrane p24 trafficking protein 7 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of TMED7 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr18:39,318,564...39,325,640
Ensembl chr18:39,297,351...39,325,640
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G |
Tnf |
tumor necrosis factor |
multiple interactions decreases expression |
ISO EXP |
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of TNF]; Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of TNF protein]] Rimonabant results in decreased expression of TNF mRNA |
CTD |
PMID:20110567 PMID:30365523 PMID:30769029 PMID:32832534 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tomm20 |
translocase of outer mitochondrial membrane 20 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TOMM20 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr19:54,925,197...54,935,188
Ensembl chr19:54,923,402...54,935,198
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G |
Tpm4 |
tropomyosin 4 |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of TPM4 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of TPM4 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; Rimonabant inhibits the reaction [Capsaicin binds to and results in increased activity of TRPV1 protein]; Rimonabant inhibits the reaction [N-(4-hydroxyphenyl)arachidonylamide binds to and results in increased activity of TRPV1 protein] |
CTD |
PMID:11278420 |
|
NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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G |
Tsen2 |
tRNA splicing endonuclease subunit 2 |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of TSEN2 mRNA Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TSEN2 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 4:148,602,805...148,638,219
Ensembl chr 4:148,602,863...148,638,215
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G |
Tspan5 |
tetraspanin 5 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TSPAN5 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 2:227,294,180...227,469,361
Ensembl chr 2:227,294,217...227,465,664
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G |
Txnrd1 |
thioredoxin reductase 1 |
increases expression |
EXP |
Rimonabant results in increased expression of TXNRD1 mRNA |
CTD |
PMID:30365523 |
|
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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G |
Unc5b |
unc-5 netrin receptor B |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of UNC5B mRNA] |
CTD |
PMID:30910812 |
|
NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537
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G |
Usp46 |
ubiquitin specific peptidase 46 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of USP46 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr14:34,150,055...34,219,227
Ensembl chr14:34,150,004...34,219,227
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G |
Usp48 |
ubiquitin specific peptidase 48 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of USP48 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 5:149,800,189...149,867,838
Ensembl chr 5:149,800,179...149,867,719
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions decreases expression |
ISO |
Rimonabant inhibits the reaction [Glucose results in increased expression of VCAM1 protein] Rimonabant results in decreased expression of VCAM1 protein |
CTD |
PMID:21373835 |
|
NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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G |
Vcl |
vinculin |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of VCL mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of and results in decreased secretion of VEGFA protein] |
CTD |
PMID:15313899 |
|
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Vim |
vimentin |
multiple interactions affects expression |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of VIM mRNA] Rimonabant affects the expression of VIM mRNA |
CTD |
PMID:19030233 |
|
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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G |
Vldlr |
very low density lipoprotein receptor |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of VLDLR mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
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G |
Wdr26 |
WD repeat domain 26 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WDR26 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr13:92,930,282...92,972,061
Ensembl chr13:92,930,285...92,977,295
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G |
Wdr7 |
WD repeat domain 7 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of WDR7 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr18:57,165,482...57,448,568
Ensembl chr18:57,165,488...57,448,540
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G |
Wsb1 |
WD repeat and SOCS box-containing 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WSB1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr10:64,202,761...64,219,039
Ensembl chr10:64,202,763...64,219,019
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G |
Wwp1 |
WW domain containing E3 ubiquitin protein ligase 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WWP1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 5:33,092,379...33,185,887
Ensembl chr 5:33,098,494...33,186,046
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G |
Wwtr1 |
WW domain containing transcription regulator 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WWTR1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 2:141,651,159...141,766,919
Ensembl chr 2:141,648,108...141,766,968
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G |
Xbp1 |
X-box binding protein 1 |
increases expression multiple interactions |
ISO |
Rimonabant results in increased expression of XBP1 mRNA [Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of XBP1 mRNA alternative form]; Gemcitabine promotes the reaction [Rimonabant results in increased expression of XBP1 mRNA] |
CTD |
PMID:21525939 PMID:31054322 |
|
NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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G |
Zdhhc2 |
zinc finger DHHC-type palmitoyltransferase 2 |
affects expression multiple interactions |
ISO |
Rimonabant affects the expression of ZDHHC2 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ZDHHC2 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr16:51,808,465...51,878,060
Ensembl chr16:51,808,468...51,878,060
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G |
Zdhhc7 |
zinc finger DHHC-type palmitoyltransferase 7 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of ZDHHC7 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr19:48,139,309...48,156,673
Ensembl chr19:48,139,527...48,156,673
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G |
Zhx1 |
zinc fingers and homeoboxes 1 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ZHX1 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 7:89,582,363...89,611,337
Ensembl chr 7:89,582,243...89,611,264
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G |
Znrf2 |
zinc and ring finger 2 |
multiple interactions |
ISO |
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ZNRF2 mRNA] |
CTD |
PMID:19030233 |
|
NCBI chr 4:83,950,406...84,032,676
Ensembl chr 4:83,949,309...84,027,818
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G |
Zwilch |
zwilch kinetochore protein |
affects expression |
ISO |
Rimonabant affects the expression of ZWILCH mRNA |
CTD |
PMID:19030233 |
|
NCBI chr 8:64,638,401...64,670,911
Ensembl chr 8:64,637,672...64,675,916
|
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