Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:amidopiperidine
go back to main search page
Accession:CHEBI:48613 term browser browse the term
Synonyms:related_synonym: amidopiperidines


show annotations for term's descendants           Sort by:
 
AM-251 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
increases expression
ISO 4'-methoxy-1-naphthylfenoterol inhibits the reaction [AM 251 results in increased expression of ABCG2 protein]; 4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid inhibits the reaction [AM 251 results in increased expression of ABCG2 protein] CTD PMID:27423937 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO AM 251 inhibits the reaction [Dronabinol results in decreased phosphorylation of and results in decreased activity of AKT1 protein] CTD PMID:17583570 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 decreases expression ISO AM 251 results in decreased expression of ARPC4 mRNA CTD PMID:16500647 NCBI chr 4:145,330,457...145,340,985
Ensembl chr 4:145,330,457...145,340,984
JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 increases expression ISO AM 251 results in increased expression of ARPP21 mRNA CTD PMID:16500647 NCBI chr 8:120,323,895...120,492,790
Ensembl chr 8:120,323,897...120,446,507
JBrowse link
G Ass1 argininosuccinate synthase 1 increases expression ISO AM 251 results in increased expression of ASS1 mRNA CTD PMID:16500647 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Atf5 activating transcription factor 5 increases expression ISO AM 251 results in increased expression of ATF5 mRNA CTD PMID:16500647 NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522
JBrowse link
G Bdkrb1 bradykinin receptor B1 multiple interactions ISO AM 251 inhibits the reaction [anandamide results in decreased activity of BDKRB1 protein] CTD PMID:19022239 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Cap2 cyclase associated actin cytoskeleton regulatory protein 2 decreases expression ISO AM 251 results in decreased expression of CAP2 mRNA CTD PMID:16500647 NCBI chr17:18,441,614...18,592,866
Ensembl chr17:18,442,127...18,592,750
JBrowse link
G Cars cysteinyl-tRNA synthetase increases expression ISO AM 251 results in increased expression of CARS1 mRNA CTD PMID:16500647 NCBI chr 1:216,759,367...216,801,652
Ensembl chr 1:216,759,366...216,801,656
JBrowse link
G Cavin2 caveolae associated protein 2 decreases expression ISO AM 251 results in decreased expression of CAVIN2 mRNA CTD PMID:16500647 NCBI chr 9:55,244,136...55,256,153
Ensembl chr 9:55,243,255...55,256,340
JBrowse link
G Ccdc86 coiled-coil domain containing 86 decreases expression ISO AM 251 results in decreased expression of CCDC86 mRNA CTD PMID:16500647 NCBI chr 1:226,996,435...227,002,016
Ensembl chr 1:226,996,237...227,002,139
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) increases expression ISO AM 251 results in increased expression of CD55 mRNA CTD PMID:16500647 NCBI chr13:47,125,156...47,153,557
Ensembl chr13:47,126,741...47,154,292
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma increases expression ISO AM 251 results in increased expression of CEBPG mRNA CTD PMID:16500647 NCBI chr 1:91,286,956...91,297,459
Ensembl chr 1:91,287,917...91,296,656
JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit increases expression ISO AM 251 results in increased expression of CHRNB3 mRNA CTD PMID:16500647 NCBI chr16:68,876,442...68,913,628
Ensembl chr16:68,875,709...68,913,628
JBrowse link
G Cklf chemokine-like factor increases expression ISO AM 251 results in increased expression of CKLF mRNA CTD PMID:16500647 NCBI chr19:903,609...914,880
Ensembl chr19:906,411...914,880
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
decreases activity
ISO
EXP
[AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to 1-(5-fluoropentyl)-3-(1-naphthoyl)indole; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to 1-pentyl-3-(1-naphthoyl)indole; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to 4-ethylnaphthalen-1-yl-(1-pentylindol-3-yl)methanone; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to CP 47497; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to CP 47497 analog; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to HU 211
AM 251 results in decreased activity of CNR1 protein
[AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased activity of nimesulide; AM 251 binds to and results in decreased activity of CNR1 protein
CTD PMID:12509806, PMID:17596442, PMID:20590570, PMID:21907772, PMID:24211273, PMID:31622603 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 multiple interactions
decreases expression
ISO AM 251 inhibits the reaction [Ethanol results in increased cleavage of and results in increased activity of CREB3L3 protein]; AM 251 inhibits the reaction [Ethanol results in increased expression of CREB3L3 mRNA]
AM 251 results in decreased expression of CREB3L3 mRNA
CTD PMID:23894352 NCBI chr 7:11,490,852...11,499,287
Ensembl chr 7:11,490,852...11,499,282
JBrowse link
G Cth cystathionine gamma-lyase increases expression ISO AM 251 results in increased expression of CTH mRNA CTD PMID:16500647 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO AM 251 inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]; AM 251 promotes the reaction [iodopravadoline inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]]; iodopravadoline promotes the reaction [AM 251 inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]] CTD PMID:17484889 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions ISO AM 251 inhibits the reaction [Ethanol results in increased expression of CYP27A1 mRNA] CTD PMID:23894352 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO AM 251 inhibits the reaction [Ethanol results in increased expression of CYP7A1 mRNA] CTD PMID:23894352 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression
multiple interactions
ISO AM 251 results in decreased expression of CYP7B1 mRNA
AM 251 inhibits the reaction [Ethanol results in increased expression of CYP7B1 mRNA]
CTD PMID:23894352 NCBI chr 2:102,701,903...102,871,257
Ensembl chr 2:102,701,903...102,871,257
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions ISO AM 251 inhibits the reaction [Ethanol results in increased expression of CYP8B1 mRNA] CTD PMID:23894352 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO AM 251 results in increased expression of DDIT3 mRNA CTD PMID:16500647 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO AM 251 results in increased expression of DDIT4 mRNA CTD PMID:16500647 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Dhx9 DExH-box helicase 9 decreases expression ISO AM 251 results in decreased expression of DHX9 mRNA CTD PMID:16500647 NCBI chr13:70,885,503...70,922,278
Ensembl chr13:70,885,504...70,922,245
JBrowse link
G Eftud2 elongation factor Tu GTP binding domain containing 2 decreases expression ISO AM 251 results in decreased expression of EFTUD2 mRNA CTD PMID:16500647 NCBI chr10:90,932,071...90,983,971
Ensembl chr10:90,932,075...90,983,928
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases expression
ISO 4'-methoxy-1-naphthylfenoterol inhibits the reaction [AM 251 results in increased expression of EGFR protein]; 4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid inhibits the reaction [AM 251 results in increased expression of EGFR protein] CTD PMID:27423937 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Ervfrd-1 endogenous retrovirus group FRD member 1, envelope multiple interactions ISO AM 251 affects the reaction [Dronabinol results in decreased expression of ERVFRD-1 mRNA] CTD PMID:26070387 NCBI chr12:25,161,130...25,168,182
Ensembl chr12:25,161,130...25,168,182
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO [AM 251 co-treated with iodopravadoline] promotes the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]; [AM 251 co-treated with iodopravadoline] promotes the reaction [methanandamide promotes the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]] CTD PMID:27556861 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fen1 flap structure-specific endonuclease 1 decreases expression ISO AM 251 results in decreased expression of FEN1 mRNA CTD PMID:16500647 NCBI chr 1:226,251,516...226,256,160
Ensembl chr 1:226,251,518...226,255,886
JBrowse link
G Fra10ac1 FRA10A associated CGG repeat 1 increases expression ISO AM 251 results in increased expression of FRA10AC1 mRNA CTD PMID:16500647 NCBI chr 1:256,881,688...256,913,617
Ensembl chr 1:256,881,771...256,914,260
JBrowse link
G Gpr55 G protein-coupled receptor 55 multiple interactions
increases activity
ISO 4'-methoxy-1-naphthylfenoterol inhibits the reaction [AM 251 results in increased activity of GPR55 protein]; 4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid inhibits the reaction [AM 251 results in increased activity of GPR55 protein] CTD PMID:27423937 NCBI chr 9:92,961,431...93,011,157
Ensembl chr 9:92,962,738...92,963,697
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO AM 251 results in increased expression of GPX1 mRNA CTD PMID:16500647 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gtf3c5 general transcription factor IIIC subunit 5 decreases expression ISO AM 251 results in decreased expression of GTF3C5 mRNA CTD PMID:16500647 NCBI chr 3:7,144,354...7,164,678
Ensembl chr 3:7,144,250...7,164,654
JBrowse link
G Hax1 HCLS1 associated protein X-1 increases expression ISO AM 251 results in increased expression of HAX1 mRNA CTD PMID:16500647 NCBI chr 2:189,330,900...189,333,305
Ensembl chr 2:189,330,902...189,333,322
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO AM 251 results in increased expression of HMOX1 mRNA CTD PMID:16500647 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnmt histamine N-methyltransferase increases expression ISO AM 251 results in increased expression of HNMT mRNA CTD PMID:16500647 NCBI chr 3:905,111...937,038
Ensembl chr 3:904,765...937,102
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B decreases expression ISO AM 251 results in decreased expression of HSPA1B mRNA CTD PMID:16500647 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO AM 251 results in decreased expression of HSPA8 mRNA CTD PMID:16500647 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO AM 251 inhibits the reaction [Cannabidiol results in increased expression of ICAM1 mRNA] CTD PMID:22198381 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [AM 251 co-treated with iodopravadoline] promotes the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]; [AM 251 co-treated with iodopravadoline] promotes the reaction [methanandamide promotes the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]] CTD PMID:27556861 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Immp2l inner mitochondrial membrane peptidase subunit 2 increases expression ISO AM 251 results in increased expression of IMMP2L mRNA CTD PMID:16500647 NCBI chr 6:60,958,351...61,859,457 JBrowse link
G Irf2bpl interferon regulatory factor 2 binding protein-like increases expression ISO AM 251 results in increased expression of IRF2BPL mRNA CTD PMID:16500647 NCBI chr 6:110,901,940...110,904,288
Ensembl chr 6:110,901,940...110,904,288
JBrowse link
G Lmnb2 lamin B2 decreases expression ISO AM 251 results in decreased expression of LMNB2 mRNA CTD PMID:16500647 NCBI chr 7:11,657,870...11,676,936
Ensembl chr 7:11,660,934...11,675,472
JBrowse link
G LOC103690190 histone H2A type 1-E increases expression ISO AM 251 results in increased expression of H2AC6 mRNA CTD PMID:16500647 NCBI chr17:44,747,686...44,748,229
Ensembl chr17:44,747,796...44,748,188
Ensembl chr17:44,747,796...44,748,188
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 decreases expression ISO AM 251 results in decreased expression of MAP2K3 mRNA CTD PMID:16500647 NCBI chr10:45,089,455...45,110,802
Ensembl chr10:47,182,433...47,203,753
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO AM 251 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; AM 251 inhibits the reaction [Dronabinol results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]; AM 251 inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK1 protein]; AM 251 inhibits the reaction [methanandamide results in increased phosphorylation of MAPK1 protein]
AM 251 results in increased phosphorylation of MAPK1 protein
CTD PMID:17583570, PMID:17596442, PMID:18159069, PMID:19477951 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO AM 251 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; AM 251 inhibits the reaction [Dronabinol results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]; AM 251 inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK3 protein]; AM 251 inhibits the reaction [methanandamide results in increased phosphorylation of MAPK3 protein]
AM 251 results in increased phosphorylation of MAPK3 protein
CTD PMID:17583570, PMID:17596442, PMID:18159069, PMID:19477951 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 decreases expression ISO AM 251 results in decreased expression of MCM3 mRNA CTD PMID:16500647 NCBI chr 9:26,914,057...26,932,201
Ensembl chr 9:26,914,057...26,932,201
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO AM 251 results in decreased expression of MCM5 mRNA CTD PMID:16500647 NCBI chr19:14,523,482...14,561,281
Ensembl chr19:14,523,554...14,561,278
JBrowse link
G Mfn2 mitofusin 2 decreases expression ISO AM 251 results in decreased expression of MFN2 mRNA CTD PMID:16500647 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Ncapd3 non-SMC condensin II complex, subunit D3 decreases expression ISO AM 251 results in decreased expression of NCAPD3 mRNA CTD PMID:16500647 NCBI chr 8:28,075,629...28,145,024
Ensembl chr 8:28,075,551...28,144,741
JBrowse link
G Ncoa7 nuclear receptor coactivator 7 increases expression ISO AM 251 results in increased expression of NCOA7 mRNA CTD PMID:16500647 NCBI chr 1:29,225,727...29,386,642
Ensembl chr 1:29,225,707...29,385,199
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 multiple interactions ISO AM 251 inhibits the reaction [Dronabinol results in decreased expression of OPRL1 mRNA]; AM 251 inhibits the reaction [Dronabinol results in decreased expression of OPRL1 protein] CTD PMID:21603976 NCBI chr 3:177,223,779...177,231,663
Ensembl chr 3:177,225,737...177,231,663
JBrowse link
G Papola poly (A) polymerase alpha decreases expression ISO AM 251 results in decreased expression of PAPOLA mRNA CTD PMID:16500647 NCBI chr 6:129,609,068...129,662,002
Ensembl chr 6:129,609,074...129,661,531
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO AM 251 inhibits the reaction [HU 211 results in increased cleavage of PARP1 protein] CTD PMID:19509271 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 increases expression ISO AM 251 results in increased expression of PEA15 mRNA CTD PMID:16500647 NCBI chr13:90,579,844...90,589,466
Ensembl chr13:90,579,846...90,589,466
JBrowse link
G Ppif peptidylprolyl isomerase F decreases expression ISO AM 251 results in decreased expression of PPIF mRNA CTD PMID:16500647 NCBI chr16:1,979,191...1,985,912
Ensembl chr16:1,979,191...1,985,908
JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 decreases expression ISO AM 251 results in decreased expression of PTBP1 mRNA CTD PMID:16500647 NCBI chr 7:12,663,965...12,673,723
Ensembl chr 7:12,663,965...12,673,718
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 decreases expression ISO AM 251 results in decreased expression of RACGAP1 mRNA CTD PMID:16500647 NCBI chr 7:141,277,303...141,308,849
Ensembl chr 7:141,277,312...141,307,233
JBrowse link
G Rad54l RAD54 like decreases expression ISO AM 251 results in decreased expression of RAD54L mRNA CTD PMID:16500647 NCBI chr 5:134,948,511...134,978,125
Ensembl chr 5:134,948,512...134,978,125
JBrowse link
G Rcc1 regulator of chromosome condensation 1 decreases expression ISO AM 251 results in decreased expression of RCC1 mRNA CTD PMID:16500647 NCBI chr 5:150,508,840...150,531,062
Ensembl chr 5:150,509,040...150,525,254
JBrowse link
G Rcc1l RCC1 like decreases expression ISO AM 251 results in decreased expression of RCC1L mRNA CTD PMID:16500647 NCBI chr12:25,561,871...25,592,337
Ensembl chr12:25,561,777...25,592,342
JBrowse link
G Rfc5 replication factor C subunit 5 decreases expression ISO AM 251 results in decreased expression of RFC5 mRNA CTD PMID:16500647 NCBI chr12:44,931,494...44,941,051
Ensembl chr12:44,931,494...44,941,324
JBrowse link
G Rnaseh1 ribonuclease H1 increases expression ISO AM 251 results in increased expression of RNASEH1 mRNA CTD PMID:16500647 NCBI chr 6:47,916,188...47,925,582
Ensembl chr 6:47,916,188...47,925,571
JBrowse link
G Rpa1 replication protein A1 decreases expression ISO AM 251 results in decreased expression of RPA1 mRNA CTD PMID:16500647 NCBI chr10:62,140,419...62,191,518
Ensembl chr10:62,140,419...62,191,512
JBrowse link
G Rwdd1 RWD domain containing 1 increases expression ISO AM 251 results in increased expression of RWDD1 mRNA CTD PMID:16500647 NCBI chr20:27,534,361...27,552,225
Ensembl chr20:27,535,324...27,552,349
JBrowse link
G Sars1 seryl-tRNA synthetase 1 increases expression ISO AM 251 results in increased expression of SARS1 mRNA CTD PMID:16500647 NCBI chr 2:211,219,743...211,235,475
Ensembl chr 2:211,219,750...211,235,467
JBrowse link
G Sesn2 sestrin 2 increases expression ISO AM 251 results in increased expression of SESN2 mRNA CTD PMID:16500647 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Slc18b1 solute carrier family 18 member B1 decreases expression ISO AM 251 results in decreased expression of SLC18B1 mRNA CTD PMID:16500647 NCBI chr 1:22,705,980...22,748,571
Ensembl chr 1:22,705,916...22,748,422
JBrowse link
G Slc1a4 solute carrier family 1 member 4 increases expression ISO AM 251 results in increased expression of SLC1A4 mRNA CTD PMID:16500647 NCBI chr14:104,582,884...104,612,417
Ensembl chr14:104,581,190...104,612,597
JBrowse link
G Slc30a1 solute carrier family 30 member 1 increases expression ISO AM 251 results in increased expression of SLC30A1 mRNA CTD PMID:16500647 NCBI chr13:110,677,810...110,681,683
Ensembl chr13:110,677,810...110,681,683
JBrowse link
G Slc46a1 solute carrier family 46 member 1 increases expression ISO AM 251 results in increased expression of SLC46A1 mRNA CTD PMID:19145103 NCBI chr10:65,728,508...65,741,708
Ensembl chr10:65,733,991...65,740,828
JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression ISO AM 251 results in increased expression of SLC7A5 mRNA CTD PMID:16500647 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563
JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 decreases expression ISO AM 251 results in decreased expression of SPTBN1 mRNA CTD PMID:16500647 NCBI chr14:114,517,839...114,700,199
Ensembl chr14:114,518,816...114,692,764
JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 decreases expression ISO AM 251 results in decreased expression of SRSF1 mRNA CTD PMID:16500647 NCBI chr10:75,334,200...75,341,197
Ensembl chr10:75,335,146...75,341,197
JBrowse link
G Stam signal transducing adaptor molecule decreases expression ISO AM 251 results in decreased expression of STAM mRNA CTD PMID:16500647 NCBI chr17:81,209,795...81,256,111
Ensembl chr17:81,209,867...81,255,808
JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases expression ISO AM 251 results in decreased expression of STAT3 mRNA CTD PMID:16500647 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Sugp2 SURP and G patch domain containing 2 decreases expression ISO AM 251 results in decreased expression of SUGP2 mRNA CTD PMID:16500647 NCBI chr16:20,908,162...20,939,574
Ensembl chr16:20,910,177...20,939,545
JBrowse link
G Sun1 Sad1 and UNC84 domain containing 1 decreases expression ISO AM 251 results in decreased expression of SUN1 mRNA CTD PMID:16500647 NCBI chr12:17,488,482...17,533,334
Ensembl chr12:17,488,487...17,522,534
JBrowse link
G Tacc3 transforming, acidic coiled-coil containing protein 3 decreases expression ISO AM 251 results in decreased expression of TACC3 mRNA CTD PMID:16500647 NCBI chr14:82,336,283...82,350,069
Ensembl chr14:82,336,324...82,347,679
JBrowse link
G Tbl1x transducin (beta)-like 1 X-linked increases expression ISO AM 251 results in increased expression of TBL1X mRNA CTD PMID:16500647 NCBI chr  X:44,959,883...44,988,551
Ensembl chr  X:44,830,849...44,988,551
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO [iodopravadoline co-treated with AM 251] inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]; [iodopravadoline co-treated with AM 251] inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]; AM 251 inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]; AM 251 inhibits the reaction [methanandamide results in increased expression of TIMP1 protein] CTD PMID:18159069 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tmem126a transmembrane protein 126A increases expression ISO AM 251 results in increased expression of TMEM126A mRNA CTD PMID:16500647 NCBI chr 1:156,283,105...156,291,057
Ensembl chr 1:156,283,128...156,291,052
JBrowse link
G Tnf tumor necrosis factor decreases response to substance ISO AM 251 results in decreased susceptibility to TNF protein CTD PMID:20626112 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO AM 251 results in increased expression of TRIB3 mRNA CTD PMID:16500647 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Tspan10 tetraspanin 10 increases expression ISO AM 251 results in increased expression of TSPAN10 mRNA CTD PMID:16500647 NCBI chr10:109,614,664...109,619,581
Ensembl chr10:109,614,965...109,618,807
JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO AM 251 results in increased expression of TXNIP mRNA CTD PMID:16500647 NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase decreases expression ISO AM 251 results in decreased expression of UGCG mRNA CTD PMID:16500647 NCBI chr 5:76,376,722...76,419,564
Ensembl chr 5:76,386,836...76,419,560
JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 decreases expression ISO AM 251 results in decreased expression of UHRF1 mRNA CTD PMID:16500647 NCBI chr 9:10,738,211...10,758,403
Ensembl chr 9:10,738,222...10,757,954
JBrowse link
G Vldlr very low density lipoprotein receptor increases expression ISO AM 251 results in increased expression of VLDLR mRNA CTD PMID:16500647 NCBI chr 1:245,236,819...245,273,688
Ensembl chr 1:245,237,736...245,269,205
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 increases expression ISO AM 251 results in increased expression of WARS1 mRNA CTD PMID:16500647 NCBI chr 6:132,771,026...132,802,262
Ensembl chr 6:132,771,021...132,802,210
JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO AM 251 results in increased expression of XBP1 mRNA CTD PMID:16500647 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 increases expression ISO AM 251 results in increased expression of YARS1 mRNA CTD PMID:16500647 NCBI chr 5:147,375,350...147,403,578
Ensembl chr 5:147,375,350...147,403,571
JBrowse link
G Zfp142 zinc finger protein 142 decreases expression ISO AM 251 results in decreased expression of ZNF142 mRNA CTD PMID:16500647 NCBI chr 9:81,844,138...81,868,086
Ensembl chr 9:81,844,138...81,868,086
JBrowse link
G Zmym6 zinc finger MYM-type containing 6 increases expression ISO AM 251 results in increased expression of ZMYM6 mRNA CTD PMID:16500647 NCBI chr 5:145,138,667...145,186,285
Ensembl chr 5:145,138,697...145,186,357
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      atom 19808
        nonmetal atom 19683
          nitrogen atom 18565
            nitrogen molecular entity 18565
              organonitrogen compound 18335
                organonitrogen heterocyclic compound 17481
                  piperidines 7446
                    amidopiperidine 97
                      (2S)-4-(2,5-difluorophenyl)-N-methyl-2-phenyl-N-piperidin-4-yl-2,5-dihydro-1H-pyrrole-1-carboxamide 0
                      1-\{2-[(4-chlorophenyl)amino]-2-oxoethyl\}-N-(1-isopropylpiperidin-4-yl)-1H-indole-2-carboxamide 0
                      1-\{[5-(5-chloro-2-thienyl)isoxazol-3-yl]methyl\}-3-cyano-N-(1-isopropylpiperidin-4-yl)-7-methyl-1H-indole-2-carboxamide 0
                      1-\{[5-(5-chloro-2-thienyl)isoxazol-3-yl]methyl\}-N-(1-isopropylpiperidin-4-yl)-1H-indole-2-carboxamide 0
                      AM-251 97
                      N-(1-isopropylpiperidin-4-yl)-1-(3-methoxybenzyl)-1H-indole-2-carboxamide 0
                      N-[1-(3-methylbutyl)piperidin-4-yl]-N-\{4-[methyl(pyridin-4-yl)amino]benzyl\}-4-pentylbenzamide 0
                      [(1R)-2-(3-\{methyl[1-(naphthalen-2-ylcarbonyl)piperidin-4-yl]carbamoyl\}naphthalen-2-yl)-1-naphthalen-1-yl-2-oxoethyl]phosphonic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic group 18527
                              organic divalent group 18520
                                organodiyl group 18520
                                  carbonyl group 18427
                                    carbonyl compound 18427
                                      carboxylic acid 18108
                                        carboacyl group 17369
                                          univalent carboacyl group 17369
                                            carbamoyl group 17156
                                              carboxamide 17156
                                                monocarboxylic acid amide 14573
                                                  amidopiperidine 97
                                                    (2S)-4-(2,5-difluorophenyl)-N-methyl-2-phenyl-N-piperidin-4-yl-2,5-dihydro-1H-pyrrole-1-carboxamide 0
                                                    1-\{2-[(4-chlorophenyl)amino]-2-oxoethyl\}-N-(1-isopropylpiperidin-4-yl)-1H-indole-2-carboxamide 0
                                                    1-\{[5-(5-chloro-2-thienyl)isoxazol-3-yl]methyl\}-3-cyano-N-(1-isopropylpiperidin-4-yl)-7-methyl-1H-indole-2-carboxamide 0
                                                    1-\{[5-(5-chloro-2-thienyl)isoxazol-3-yl]methyl\}-N-(1-isopropylpiperidin-4-yl)-1H-indole-2-carboxamide 0
                                                    AM-251 97
                                                    N-(1-isopropylpiperidin-4-yl)-1-(3-methoxybenzyl)-1H-indole-2-carboxamide 0
                                                    N-[1-(3-methylbutyl)piperidin-4-yl]-N-\{4-[methyl(pyridin-4-yl)amino]benzyl\}-4-pentylbenzamide 0
                                                    [(1R)-2-(3-\{methyl[1-(naphthalen-2-ylcarbonyl)piperidin-4-yl]carbamoyl\}naphthalen-2-yl)-1-naphthalen-1-yl-2-oxoethyl]phosphonic acid 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.