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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:amidopiperidine
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Accession:CHEBI:48613 term browser browse the term
Synonyms:related_synonym: amidopiperidines


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AM-251 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
increases expression
ISO 4'-methoxy-1-naphthylfenoterol inhibits the reaction [AM 251 results in increased expression of ABCG2 protein]; 4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid inhibits the reaction [AM 251 results in increased expression of ABCG2 protein] CTD PMID:27423937 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA] CTD PMID:27936102 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Agrp agouti related neuropeptide multiple interactions
increases expression
EXP AM 251 promotes the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of AGRP mRNA]
AM 251 results in increased expression of AGRP mRNA
CTD PMID:26468265 NCBI chr19:33,447,992...33,523,068
Ensembl chr19:33,447,992...33,449,584
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO AM 251 inhibits the reaction [Dronabinol results in decreased phosphorylation of and results in decreased activity of AKT1 protein]
AM 251 inhibits the reaction [[3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide co-treated with Glutamic Acid] results in increased phosphorylation of AKT1 protein]; AM 251 inhibits the reaction [[cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester co-treated with Glutamic Acid] results in increased phosphorylation of AKT1 protein]; AM 251 inhibits the reaction [[JZL 184 co-treated with Glutamic Acid] results in increased phosphorylation of AKT1 protein]; AM 251 inhibits the reaction [Dietary Fats results in decreased expression of AKT1 protein]
CTD PMID:17583570 PMID:26847930 PMID:27543109 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 decreases expression ISO AM 251 results in decreased expression of ARPC4 mRNA CTD PMID:16500647 NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785
JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 increases expression ISO AM 251 results in increased expression of ARPP21 mRNA CTD PMID:16500647 NCBI chr 8:112,034,636...112,199,273
Ensembl chr 8:112,034,642...112,194,297
JBrowse link
G Ass1 argininosuccinate synthase 1 increases expression ISO AM 251 results in increased expression of ASS1 mRNA CTD PMID:16500647 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
JBrowse link
G Atf5 activating transcription factor 5 increases expression ISO AM 251 results in increased expression of ATF5 mRNA CTD PMID:16500647 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
JBrowse link
G Avp arginine vasopressin multiple interactions
increases expression
EXP AM 251 promotes the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of AVP mRNA]
AM 251 results in increased expression of AVP mRNA
CTD PMID:26468265 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
ISO AM 251 results in increased expression of BCL2 protein
AM 251 inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]
CTD PMID:26967640 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bdkrb1 bradykinin receptor B1 multiple interactions ISO AM 251 inhibits the reaction [anandamide results in decreased activity of BDKRB1 protein] CTD PMID:19022239 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO AM 251 inhibits the reaction [Morphine results in increased expression of BDNF protein] CTD PMID:27461790 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Btg2 BTG anti-proliferation factor 2 multiple interactions ISO AM 251 inhibits the reaction [Ethanol results in increased expression of BTG2 mRNA] CTD PMID:28095641 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Cap2 cyclase associated actin cytoskeleton regulatory protein 2 decreases expression ISO AM 251 results in decreased expression of CAP2 mRNA CTD PMID:16500647 NCBI chr17:18,054,234...18,203,453
Ensembl chr17:18,054,431...18,203,373
JBrowse link
G Cars cysteinyl-tRNA synthetase increases expression ISO AM 251 results in increased expression of CARS1 mRNA CTD PMID:16500647 NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941
JBrowse link
G Cartpt CART prepropeptide increases expression
multiple interactions
EXP AM 251 results in increased expression of CARTPT mRNA
[AM 251 co-treated with Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of CARTPT mRNA
CTD PMID:26468265 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
JBrowse link
G Cavin2 caveolae associated protein 2 decreases expression ISO AM 251 results in decreased expression of CAVIN2 mRNA CTD PMID:16500647 NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147
JBrowse link
G Ccdc86 coiled-coil domain containing 86 decreases expression ISO AM 251 results in decreased expression of CCDC86 mRNA CTD PMID:16500647 NCBI chr 1:207,590,946...207,596,527
Ensembl chr 1:207,590,168...207,596,544
JBrowse link
G Ccnd2 cyclin D2 increases expression
multiple interactions
ISO AM 251 results in increased expression of CCND2 protein
AM 251 inhibits the reaction [Streptozocin results in decreased expression of CCND2 protein]
CTD PMID:26967640 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) increases expression ISO AM 251 results in increased expression of CD55 mRNA CTD PMID:16500647 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
JBrowse link
G Cdh1 cadherin 1 increases expression
multiple interactions
ISO AM 251 results in increased expression of CDH1 protein
AM 251 inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 protein]
CTD PMID:27936102 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma increases expression ISO AM 251 results in increased expression of CEBPG mRNA CTD PMID:16500647 NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit increases expression ISO AM 251 results in increased expression of CHRNB3 mRNA CTD PMID:16500647 NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360
JBrowse link
G Cklf chemokine-like factor increases expression ISO AM 251 results in increased expression of CKLF mRNA CTD PMID:16500647 NCBI chr19:698,097...706,570
Ensembl chr19:698,033...706,570
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
decreases activity
ISO
EXP
[AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to 1-(5-fluoropentyl)-3-(1-naphthoyl)indole; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to 1-pentyl-3-(1-naphthoyl)indole; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to 4-ethylnaphthalen-1-yl-(1-pentylindol-3-yl)methanone; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to CP 47497; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to CP 47497 analog; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to HU 211; AM 251 inhibits the reaction [Dietary Fats results in increased expression of CNR1 protein]; AM 251 inhibits the reaction [Ethanol results in increased expression of CNR1 mRNA]
AM 251 results in decreased activity of CNR1 protein
[AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased activity of nimesulide; AM 251 binds to and results in decreased activity of CNR1 protein; AM 251 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of CNR1 mRNA]; AM 251 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of CNR1 protein]; AM 251 inhibits the reaction [1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester binds to and results in increased activity of CNR1 protein]; AM 251 inhibits the reaction [1-pentyfluoro-1H-indole-3-carboxylic acid 8-quinolinyl ester binds to and results in increased activity of CNR1 protein]; AM 251 inhibits the reaction [Dietary Carbohydrates results in decreased expression of CNR1 protein]; AM 251 inhibits the reaction [HU 211 results in decreased expression of CNR1 protein]; AM 251 inhibits the reaction [N-(1-adamantyl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide binds to and results in increased activity of CNR1 protein]; AM 251 inhibits the reaction [N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide binds to and results in increased activity of CNR1 protein]
CTD PMID:12509806 PMID:17596442 PMID:20590570 PMID:21907772 PMID:24211273 More... NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] CTD PMID:27936102 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA] CTD PMID:27936102 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Col4a1 collagen type IV alpha 1 chain multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of COL4A1 mRNA] CTD PMID:27936102 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 multiple interactions EXP AM 251 inhibits the reaction [Dietary Carbohydrates results in decreased expression of COX4I1 mRNA]; AM 251 inhibits the reaction [Dietary Fats results in decreased expression of COX4I1 mRNA] CTD PMID:26671069 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO AM 251 inhibits the reaction [Dietary Fats results in decreased expression of CPT1A mRNA] CTD PMID:26847930 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO AM 251 inhibits the reaction [Morphine results in increased phosphorylation of CREB1 protein] CTD PMID:27461790 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 multiple interactions
decreases expression
ISO AM 251 inhibits the reaction [Ethanol results in increased cleavage of and results in increased activity of CREB3L3 protein]; AM 251 inhibits the reaction [Ethanol results in increased expression of CREB3L3 mRNA]
AM 251 results in decreased expression of CREB3L3 mRNA
CTD PMID:23894352 NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048
JBrowse link
G Crh corticotropin releasing hormone multiple interactions
increases expression
EXP [AM 251 co-treated with Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of CRH mRNA
AM 251 results in increased expression of CRH mRNA
CTD PMID:26468265 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Cs citrate synthase multiple interactions ISO AM 251 inhibits the reaction [Dietary Fats results in decreased expression of CS mRNA] CTD PMID:26847930 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
JBrowse link
G Cth cystathionine gamma-lyase increases expression ISO AM 251 results in increased expression of CTH mRNA CTD PMID:16500647 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO AM 251 inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]; AM 251 promotes the reaction [iodopravadoline inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]]; iodopravadoline promotes the reaction [AM 251 inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]] CTD PMID:17484889 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions ISO AM 251 inhibits the reaction [Ethanol results in increased expression of CYP27A1 mRNA] CTD PMID:23894352 PMID:28095641 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO AM 251 inhibits the reaction [Ethanol results in increased expression of CYP7A1 mRNA] CTD PMID:23894352 PMID:28095641 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression
multiple interactions
ISO AM 251 results in decreased expression of CYP7B1 mRNA
AM 251 inhibits the reaction [Ethanol results in increased expression of CYP7B1 mRNA]
CTD PMID:23894352 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions ISO AM 251 inhibits the reaction [Ethanol results in increased expression of CYP8B1 mRNA] CTD PMID:23894352 PMID:28095641 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO AM 251 results in increased expression of DDIT3 mRNA CTD PMID:16500647 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO AM 251 results in increased expression of DDIT4 mRNA CTD PMID:16500647 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Dhx9 DExH-box helicase 9 decreases expression ISO AM 251 results in decreased expression of DHX9 mRNA CTD PMID:16500647 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
JBrowse link
G Dld dihydrolipoamide dehydrogenase multiple interactions
decreases expression
increases activity
EXP
ISO
AM 251 inhibits the reaction [Dietary Carbohydrates results in decreased expression of DLD mRNA]; AM 251 inhibits the reaction [Dietary Carbohydrates results in decreased expression of DLD protein]
AM 251 promotes the reaction [INS1 protein results in increased activity of DLD protein]
AM 251 results in decreased expression of DLD mRNA
AM 251 results in increased activity of DLD protein
CTD PMID:26671069 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
JBrowse link
G Eftud2 elongation factor Tu GTP binding domain containing 2 decreases expression ISO AM 251 results in decreased expression of EFTUD2 mRNA CTD PMID:16500647 NCBI chr10:87,804,893...87,852,181
Ensembl chr10:87,804,892...87,846,079
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases expression
ISO 4'-methoxy-1-naphthylfenoterol inhibits the reaction [AM 251 results in increased expression of EGFR protein]; 4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid inhibits the reaction [AM 251 results in increased expression of EGFR protein] CTD PMID:27423937 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eno3 enolase 3 multiple interactions EXP AM 251 inhibits the reaction [Dietary Carbohydrates results in increased expression of ENO3 protein] CTD PMID:26671069 NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921
JBrowse link
G Ervfrd-1 endogenous retrovirus group FRD member 1, envelope multiple interactions ISO AM 251 affects the reaction [Dronabinol results in decreased expression of ERVFRD-1 mRNA] CTD PMID:26070387 NCBI chr12:22,151,211...22,158,264
Ensembl chr12:22,151,211...22,158,264
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO [AM 251 co-treated with iodopravadoline] promotes the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]; [AM 251 co-treated with iodopravadoline] promotes the reaction [methanandamide promotes the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]] CTD PMID:27556861 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fen1 flap structure-specific endonuclease 1 decreases expression ISO AM 251 results in decreased expression of FEN1 mRNA CTD PMID:16500647 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO AM 251 inhibits the reaction [Dietary Fats results in increased expression of FOS protein]; AM 251 inhibits the reaction [LEP gene mutant form results in increased expression of FOS protein] CTD PMID:27071101 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of FOSB mRNA]
AM 251 results in increased expression of FOSB mRNA
CTD PMID:27936102 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO AM 251 inhibits the reaction [Dietary Fats results in decreased phosphorylation of FOXO1 protein] CTD PMID:26847930 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Fra10ac1 FRA10A associated CGG repeat 1 increases expression ISO AM 251 results in increased expression of FRA10AC1 mRNA CTD PMID:16500647 NCBI chr 1:235,969,071...236,001,074
Ensembl chr 1:235,969,112...236,001,210
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO AM 251 inhibits the reaction [Dietary Fats results in increased expression of G6PC protein] CTD PMID:26847930 NCBI chr10:86,307,400...86,318,766 JBrowse link
G Glo1 glyoxalase 1 decreases expression
multiple interactions
EXP AM 251 results in decreased expression of GLO1 protein
AM 251 inhibits the reaction [Dietary Carbohydrates results in decreased expression of GLO1 protein]; AM 251 inhibits the reaction [Dietary Fats results in decreased expression of GLO1 protein]
CTD PMID:26671069 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Gpi glucose-6-phosphate isomerase multiple interactions
decreases expression
EXP AM 251 inhibits the reaction [Dietary Carbohydrates results in increased expression of GPI protein]
AM 251 results in decreased expression of GPI protein
CTD PMID:26671069 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
JBrowse link
G Gpr55 G protein-coupled receptor 55 multiple interactions
increases activity
ISO 4'-methoxy-1-naphthylfenoterol inhibits the reaction [AM 251 results in increased activity of GPR55 protein]; 4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid inhibits the reaction [AM 251 results in increased activity of GPR55 protein] CTD PMID:27423937 NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO AM 251 results in increased expression of GPX1 mRNA CTD PMID:16500647 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO AM 251 promotes the reaction [INS1 protein results in increased activity of GSR protein] CTD PMID:26671069 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gtf3c5 general transcription factor IIIC subunit 5 decreases expression ISO AM 251 results in decreased expression of GTF3C5 mRNA CTD PMID:16500647 NCBI chr 3:11,893,867...11,914,187
Ensembl chr 3:11,893,875...11,914,180
JBrowse link
G Hax1 HCLS1 associated protein X-1 increases expression ISO AM 251 results in increased expression of HAX1 mRNA CTD PMID:16500647 NCBI chr 2:175,434,242...175,437,926
Ensembl chr 2:175,434,238...175,437,714
JBrowse link
G Hcrt hypocretin neuropeptide precursor multiple interactions EXP
ISO
AM 251 inhibits the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of HCRT mRNA]
AM 251 inhibits the reaction [Dietary Fats results in increased expression of HCRT protein modified form]; AM 251 inhibits the reaction [HCRT protein modified form results in increased expression of POMC mRNA]; AM 251 inhibits the reaction [HCRT protein modified form results in increased expression of POMC protein modified form]; AM 251 inhibits the reaction [HCRT protein modified form results in increased expression of POMC protein]; AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of and results in increased activity of STAT3 protein]; AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of MAPK1 protein]; AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of MAPK3 protein]; AM 251 inhibits the reaction [LEP gene mutant form results in increased expression of HCRT protein modified form]
CTD PMID:26468265 PMID:27071101 NCBI chr10:85,689,992...85,691,206
Ensembl chr10:85,689,465...85,691,210
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO AM 251 results in increased expression of HMOX1 mRNA CTD PMID:16500647 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnmt histamine N-methyltransferase increases expression ISO AM 251 results in increased expression of HNMT mRNA CTD PMID:16500647 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B decreases expression ISO AM 251 results in decreased expression of HSPA1B mRNA CTD PMID:16500647 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO AM 251 results in decreased expression of HSPA8 mRNA CTD PMID:16500647 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO AM 251 inhibits the reaction [Cannabidiol results in increased expression of ICAM1 mRNA] CTD PMID:22198381 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [AM 251 co-treated with iodopravadoline] promotes the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]; [AM 251 co-treated with iodopravadoline] promotes the reaction [methanandamide promotes the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]] CTD PMID:27556861 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il33 interleukin 33 multiple interactions EXP AM 251 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Carbon Monoxide results in increased expression of IL33 protein]] CTD PMID:31732924 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Immp2l inner mitochondrial membrane peptidase subunit 2 increases expression ISO AM 251 results in increased expression of IMMP2L mRNA CTD PMID:16500647 NCBI chr 6:58,070,035...58,970,165 JBrowse link
G Irf2bpl interferon regulatory factor 2 binding protein-like increases expression ISO AM 251 results in increased expression of IRF2BPL mRNA CTD PMID:16500647 NCBI chr 6:106,527,179...106,531,294
Ensembl chr 6:106,528,053...106,530,401
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions ISO AM 251 inhibits the reaction [Dietary Fats results in decreased phosphorylation of IRS2 protein] CTD PMID:26847930 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of JUNB mRNA] CTD PMID:27936102 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions EXP AM 251 inhibits the reaction [Dietary Carbohydrates results in increased expression of LDHA protein] CTD PMID:26671069 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Lep leptin multiple interactions ISO AM 251 inhibits the reaction [LEP gene mutant form results in decreased expression of POMC mRNA]; AM 251 inhibits the reaction [LEP gene mutant form results in decreased expression of POMC protein]; AM 251 inhibits the reaction [LEP gene mutant form results in decreased secretion of POMC protein modified form]; AM 251 inhibits the reaction [LEP gene mutant form results in increased expression of FOS protein]; AM 251 inhibits the reaction [LEP gene mutant form results in increased expression of HCRT protein modified form] CTD PMID:27071101 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lmnb2 lamin B2 decreases expression ISO AM 251 results in decreased expression of LMNB2 mRNA CTD PMID:16500647 NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665
JBrowse link
G LOC103690190 histone H2A type 1-E increases expression ISO AM 251 results in increased expression of H2AC6 mRNA CTD PMID:16500647 NCBI chr17:42,707,863...42,708,420 JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 decreases expression ISO AM 251 results in decreased expression of MAP2K3 mRNA CTD PMID:16500647 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO AM 251 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; AM 251 inhibits the reaction [Dronabinol results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]; AM 251 inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK1 protein]; AM 251 inhibits the reaction [methanandamide results in increased phosphorylation of MAPK1 protein]
AM 251 inhibits the reaction [[3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide co-treated with Glutamic Acid] results in increased phosphorylation of MAPK1 protein]; AM 251 inhibits the reaction [[cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester co-treated with Glutamic Acid] results in increased phosphorylation of MAPK1 protein]; AM 251 inhibits the reaction [[JZL 184 co-treated with Glutamic Acid] results in increased phosphorylation of MAPK1 protein]; AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of MAPK1 protein]; AM 251 inhibits the reaction [Morphine results in increased phosphorylation of MAPK1 protein]
AM 251 results in increased phosphorylation of MAPK1 protein
CTD PMID:17583570 PMID:17596442 PMID:18159069 PMID:19477951 PMID:27071101 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO AM 251 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; AM 251 inhibits the reaction [Dronabinol results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]; AM 251 inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK3 protein]; AM 251 inhibits the reaction [methanandamide results in increased phosphorylation of MAPK3 protein]
AM 251 inhibits the reaction [[3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide co-treated with Glutamic Acid] results in increased phosphorylation of MAPK3 protein]; AM 251 inhibits the reaction [[cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester co-treated with Glutamic Acid] results in increased phosphorylation of MAPK3 protein]; AM 251 inhibits the reaction [[JZL 184 co-treated with Glutamic Acid] results in increased phosphorylation of MAPK3 protein]; AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of MAPK3 protein]; AM 251 inhibits the reaction [Morphine results in increased phosphorylation of MAPK3 protein]
AM 251 results in increased phosphorylation of MAPK3 protein
CTD PMID:17583570 PMID:17596442 PMID:18159069 PMID:19477951 PMID:27071101 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 decreases expression ISO AM 251 results in decreased expression of MCM3 mRNA CTD PMID:16500647 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO AM 251 results in decreased expression of MCM5 mRNA CTD PMID:16500647 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
JBrowse link
G Mfn2 mitofusin 2 decreases expression ISO AM 251 results in decreased expression of MFN2 mRNA CTD PMID:16500647 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of MMP2 mRNA]
AM 251 results in increased expression of MMP2 protein
CTD PMID:27936102 PMID:29883990 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Ncapd3 non-SMC condensin II complex, subunit D3 decreases expression ISO AM 251 results in decreased expression of NCAPD3 mRNA CTD PMID:16500647 NCBI chr 8:25,437,067...25,506,375
Ensembl chr 8:25,437,123...25,506,373
JBrowse link
G Ncoa7 nuclear receptor coactivator 7 increases expression ISO AM 251 results in increased expression of NCOA7 mRNA CTD PMID:16500647 NCBI chr 1:26,856,228...27,016,950
Ensembl chr 1:26,856,530...27,015,871
JBrowse link
G Npy neuropeptide Y multiple interactions EXP [AM 251 co-treated with Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of NPY mRNA CTD PMID:26468265 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Nrf1 nuclear respiratory factor 1 multiple interactions ISO AM 251 inhibits the reaction [Dietary Fats results in decreased expression of NRF1 mRNA] CTD PMID:26847930 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 multiple interactions ISO AM 251 inhibits the reaction [Dronabinol results in decreased expression of OPRL1 mRNA]; AM 251 inhibits the reaction [Dronabinol results in decreased expression of OPRL1 protein] CTD PMID:21603976 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide multiple interactions
increases secretion
increases expression
EXP AM 251 promotes the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of OXT mRNA]
AM 251 results in increased secretion of OXT protein
AM 251 results in increased expression of OXT mRNA
CTD PMID:26468265 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
JBrowse link
G Papola poly (A) polymerase alpha decreases expression ISO AM 251 results in decreased expression of PAPOLA mRNA CTD PMID:16500647 NCBI chr 6:124,682,015...124,734,706
Ensembl chr 6:124,682,105...124,734,468
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO AM 251 inhibits the reaction [HU 211 results in increased cleavage of PARP1 protein] CTD PMID:19509271 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO AM 251 inhibits the reaction [Dietary Fats results in increased expression of PCK1 mRNA]; AM 251 inhibits the reaction [Dietary Fats results in increased expression of PCK1 protein] CTD PMID:26847930 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 increases expression ISO AM 251 results in increased expression of PEA15 mRNA CTD PMID:16500647 NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499
JBrowse link
G Pomc proopiomelanocortin multiple interactions
increases expression
EXP
ISO
AM 251 promotes the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of POMC mRNA]
AM 251 inhibits the reaction [Dietary Fats results in decreased expression of POMC mRNA]; AM 251 inhibits the reaction [Dietary Fats results in decreased expression of POMC protein]; AM 251 inhibits the reaction [Dietary Fats results in decreased secretion of POMC protein modified form]; AM 251 inhibits the reaction [HCRT protein modified form results in increased expression of POMC mRNA]; AM 251 inhibits the reaction [HCRT protein modified form results in increased expression of POMC protein modified form]; AM 251 inhibits the reaction [HCRT protein modified form results in increased expression of POMC protein]; AM 251 inhibits the reaction [LEP gene mutant form results in decreased expression of POMC mRNA]; AM 251 inhibits the reaction [LEP gene mutant form results in decreased expression of POMC protein]; AM 251 inhibits the reaction [LEP gene mutant form results in decreased secretion of POMC protein modified form]
AM 251 results in increased expression of POMC mRNA
CTD PMID:26468265 PMID:27071101 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Ppif peptidylprolyl isomerase F decreases expression ISO AM 251 results in decreased expression of PPIF mRNA CTD PMID:16500647 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 decreases expression ISO AM 251 results in decreased expression of PTBP1 mRNA CTD PMID:16500647 NCBI chr 7:9,842,574...9,852,332
Ensembl chr 7:9,842,574...9,852,397
JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO [AM 251 co-treated with iodopravadoline] inhibits the reaction [Dronabinol results in increased phosphorylation of PTK2 protein] CTD PMID:31461164 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 decreases expression ISO AM 251 results in decreased expression of RACGAP1 mRNA CTD PMID:16500647 NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
JBrowse link
G Rad54l RAD54 like decreases expression ISO AM 251 results in decreased expression of RAD54L mRNA CTD PMID:16500647 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070
JBrowse link
G Rcc1 regulator of chromosome condensation 1 decreases expression ISO AM 251 results in decreased expression of RCC1 mRNA CTD PMID:16500647 NCBI chr 5:144,526,025...144,544,445
Ensembl chr 5:144,526,025...144,544,577
JBrowse link
G Rcc1l RCC1 like decreases expression ISO AM 251 results in decreased expression of RCC1L mRNA CTD PMID:16500647 NCBI chr12:22,543,125...22,574,042
Ensembl chr12:22,543,734...22,574,036
JBrowse link
G Rfc5 replication factor C subunit 5 decreases expression ISO AM 251 results in decreased expression of RFC5 mRNA CTD PMID:16500647 NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312
JBrowse link
G Rnaseh1 ribonuclease H1 increases expression ISO AM 251 results in increased expression of RNASEH1 mRNA CTD PMID:16500647 NCBI chr 6:45,282,849...45,292,258
Ensembl chr 6:45,282,854...45,292,236
JBrowse link
G Rpa1 replication protein A1 decreases expression ISO AM 251 results in decreased expression of RPA1 mRNA CTD PMID:16500647 NCBI chr10:60,148,869...60,199,999
Ensembl chr10:60,148,793...60,199,949
JBrowse link
G Rwdd1 RWD domain containing 1 increases expression ISO AM 251 results in increased expression of RWDD1 mRNA CTD PMID:16500647 NCBI chr20:25,949,723...25,967,147
Ensembl chr20:25,941,966...25,967,193
JBrowse link
G S100a2 S100 calcium binding protein A2 increases expression ISO AM 251 results in increased expression of S100A2 mRNA CTD PMID:16500647 NCBI chr 2:176,075,060...176,078,782 JBrowse link
G Sars1 seryl-tRNA synthetase 1 increases expression ISO AM 251 results in increased expression of SARS1 mRNA CTD PMID:16500647 NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277
JBrowse link
G Sesn2 sestrin 2 increases expression ISO AM 251 results in increased expression of SESN2 mRNA CTD PMID:16500647 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Slc18b1 solute carrier family 18 member B1 decreases expression ISO AM 251 results in decreased expression of SLC18B1 mRNA CTD PMID:16500647 NCBI chr 1:21,628,232...21,670,807
Ensembl chr 1:21,628,237...21,670,684
JBrowse link
G Slc1a4 solute carrier family 1 member 4 increases expression ISO AM 251 results in increased expression of SLC1A4 mRNA CTD PMID:16500647 NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418
JBrowse link
G Slc30a1 solute carrier family 30 member 1 increases expression ISO AM 251 results in increased expression of SLC30A1 mRNA CTD PMID:16500647 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
JBrowse link
G Slc46a1 solute carrier family 46 member 1 increases expression ISO AM 251 results in increased expression of SLC46A1 mRNA CTD PMID:19145103 NCBI chr10:63,361,504...63,367,940
Ensembl chr10:63,361,486...63,368,848
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions EXP AM 251 affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of SLC6A3 mRNA] CTD PMID:29113897 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression ISO AM 251 results in increased expression of SLC7A5 mRNA CTD PMID:16500647 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] CTD PMID:27936102 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Snai1 snail family transcriptional repressor 1 decreases expression
multiple interactions
ISO AM 251 results in decreased expression of SNAI1 mRNA
AM 251 inhibits the reaction [TGFB1 protein results in increased expression of SNAI1 mRNA]
CTD PMID:27936102 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of SNAI2 mRNA] CTD PMID:27936102 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 decreases expression ISO AM 251 results in decreased expression of SPTBN1 mRNA CTD PMID:16500647 NCBI chr14:103,842,684...104,008,507
Ensembl chr14:103,842,684...104,008,507
JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 decreases expression ISO AM 251 results in decreased expression of SRSF1 mRNA CTD PMID:16500647 NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336
JBrowse link
G Stam signal transducing adaptor molecule decreases expression ISO AM 251 results in decreased expression of STAM mRNA CTD PMID:16500647 NCBI chr17:77,120,235...77,166,173
Ensembl chr17:77,120,158...77,166,467
JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases expression
multiple interactions
ISO AM 251 results in decreased expression of STAT3 mRNA
AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of and results in increased activity of STAT3 protein]
CTD PMID:16500647 PMID:27071101 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Sugp2 SURP and G patch domain containing 2 decreases expression ISO AM 251 results in decreased expression of SUGP2 mRNA CTD PMID:16500647 NCBI chr16:19,159,951...19,191,412
Ensembl chr16:19,164,767...19,191,340
JBrowse link
G Sun1 Sad1 and UNC84 domain containing 1 decreases expression ISO AM 251 results in decreased expression of SUN1 mRNA CTD PMID:16500647 NCBI chr12:15,396,378...15,441,277
Ensembl chr12:15,396,381...15,441,571
JBrowse link
G Tacc3 transforming, acidic coiled-coil containing protein 3 decreases expression ISO AM 251 results in decreased expression of TACC3 mRNA CTD PMID:16500647 NCBI chr14:77,051,209...77,065,343
Ensembl chr14:77,051,215...77,065,219
JBrowse link
G Tbl1x transducin (beta)-like 1 X-linked increases expression ISO AM 251 results in increased expression of TBL1X mRNA CTD PMID:16500647 NCBI chr  X:41,574,558...41,731,117
Ensembl chr  X:41,576,047...41,731,101
JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions ISO AM 251 inhibits the reaction [Dietary Fats results in decreased expression of TFAM mRNA] CTD PMID:26847930 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 protein]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of COL4A1 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of FOSB mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of JUNB mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of MMP2 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of SNAI1 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of SNAI2 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of TGFB2 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of TGFB3 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of TGFBR1 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] CTD PMID:27936102 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of TGFB2 mRNA] CTD PMID:27936102 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfb3 transforming growth factor, beta 3 multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of TGFB3 mRNA] CTD PMID:27936102 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of TGFBR1 mRNA] CTD PMID:27936102 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP AM 251 affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of TH mRNA] CTD PMID:29113897 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO [iodopravadoline co-treated with AM 251] inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]; [iodopravadoline co-treated with AM 251] inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]; AM 251 inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]; AM 251 inhibits the reaction [methanandamide results in increased expression of TIMP1 protein] CTD PMID:18159069 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tmem126a transmembrane protein 126A increases expression ISO AM 251 results in increased expression of TMEM126A mRNA CTD PMID:16500647 NCBI chr 1:144,422,698...144,430,730
Ensembl chr 1:144,422,703...144,430,628
JBrowse link
G Tnf tumor necrosis factor decreases response to substance ISO AM 251 results in decreased susceptibility to TNF protein CTD PMID:20626112 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO AM 251 results in increased expression of TRIB3 mRNA CTD PMID:16500647 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Tspan10 tetraspanin 10 increases expression ISO AM 251 results in increased expression of TSPAN10 mRNA CTD PMID:16500647 NCBI chr10:105,715,803...105,721,503
Ensembl chr10:105,715,961...105,719,813
JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO AM 251 results in increased expression of TXNIP mRNA CTD PMID:16500647 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase decreases expression ISO AM 251 results in decreased expression of UGCG mRNA CTD PMID:16500647 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 decreases expression ISO AM 251 results in decreased expression of UHRF1 mRNA CTD PMID:16500647 NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO AM 251 inhibits the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of VEGFA protein]] CTD PMID:26467187 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vegfc vascular endothelial growth factor C multiple interactions ISO AM 251 inhibits the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of VEGFC protein]] CTD PMID:26467187 NCBI chr16:37,712,408...37,827,657
Ensembl chr16:37,712,262...37,827,848
JBrowse link
G Vldlr very low density lipoprotein receptor increases expression ISO AM 251 results in increased expression of VLDLR mRNA CTD PMID:16500647 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 increases expression ISO AM 251 results in increased expression of WARS1 mRNA CTD PMID:16500647 NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269
JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO AM 251 results in increased expression of XBP1 mRNA CTD PMID:16500647 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 increases expression ISO AM 251 results in increased expression of YARS1 mRNA CTD PMID:16500647 NCBI chr 5:141,535,815...141,564,029
Ensembl chr 5:141,535,759...141,563,833
JBrowse link
G Yy1 YY1 transcription factor multiple interactions ISO AM 251 inhibits the reaction [Ethanol results in increased expression of YY1 mRNA] CTD PMID:28095641 NCBI chr 6:127,706,739...127,731,907
Ensembl chr 6:127,707,596...127,732,747
JBrowse link
G Zfp142 zinc finger protein 142 decreases expression ISO AM 251 results in decreased expression of ZNF142 mRNA CTD PMID:16500647 NCBI chr 9:76,141,053...76,164,784
Ensembl chr 9:76,142,227...76,164,856
JBrowse link
G Zmym6 zinc finger MYM-type containing 6 increases expression ISO AM 251 results in increased expression of ZMYM6 mRNA CTD PMID:16500647 NCBI chr 5:139,396,374...139,444,357
Ensembl chr 5:139,396,727...139,444,279
JBrowse link
rimonabant term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha affects expression ISO Rimonabant affects the expression of ACACA mRNA CTD PMID:20110567 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acacb acetyl-CoA carboxylase beta increases expression ISO Rimonabant results in increased expression of ACACB mRNA CTD PMID:20110567 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain affects expression
multiple interactions
ISO Rimonabant affects the expression of ACADM mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ACADM mRNA]
CTD PMID:19030233 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Acbd5 acyl-CoA binding domain containing 5 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ACBD5 mRNA] CTD PMID:19030233 NCBI chr17:85,206,178...85,248,909
Ensembl chr17:85,206,303...85,248,215
JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression EXP Rimonabant results in decreased expression of ACTA2 mRNA CTD PMID:21863215 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actr2 actin related protein 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ACTR2 mRNA] CTD PMID:19030233 NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ADAMTS1 mRNA] CTD PMID:19030233 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 decreases expression EXP Rimonabant results in decreased expression of ADGRE1 mRNA CTD PMID:30365523 NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO Rimonabant results in increased expression of ADIPOQ mRNA; Rimonabant results in increased expression of ADIPOQ protein CTD PMID:16282221 PMID:20110567 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 multiple interactions
increases expression
ISO Rimonabant inhibits the reaction [MIR762 mRNA results in decreased expression of AGAP2 mRNA]; Rimonabant promotes the reaction [Dietary Fats results in increased expression of AGAP2 mRNA]
Rimonabant results in increased expression of AGAP2 mRNA
CTD PMID:30910812 NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295
JBrowse link
G Akap2 A-kinase anchoring protein 2 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PAKAP mRNA]
Rimonabant affects the expression of PAKAP mRNA
CTD PMID:19030233 NCBI chr 5:72,536,986...72,648,524
Ensembl chr 5:72,181,718...72,648,524
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP
ISO
Rimonabant inhibits the reaction [Dronabinol results in decreased phosphorylation of AKT1 protein]
Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of AKT1 protein]; Rimonabant inhibits the reaction [methanandamide results in increased phosphorylation of AKT1 protein]
CTD PMID:12834810 PMID:31917333 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Anxa1 annexin A1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ANXA1 mRNA] CTD PMID:19030233 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Anxa2 annexin A2 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ANXA2 mRNA]
Rimonabant affects the expression of ANXA2 mRNA
CTD PMID:19030233 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Apob apolipoprotein B increases secretion ISO Rimonabant results in increased secretion of APOB protein CTD PMID:20110567 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G App amyloid beta precursor protein affects expression
multiple interactions
ISO Rimonabant affects the expression of APP mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of APP mRNA]
CTD PMID:19030233 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Arg1 arginase 1 multiple interactions ISO Rimonabant promotes the reaction [Dietary Fats results in increased expression of ARG1] CTD PMID:30910812 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arhgef12 Rho guanine nucleotide exchange factor 12 affects expression
multiple interactions
ISO Rimonabant affects the expression of ARHGEF12 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ARHGEF12 mRNA]
CTD PMID:19030233 NCBI chr 8:43,350,070...43,475,404
Ensembl chr 8:43,353,799...43,476,366
JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ARPP19 mRNA] CTD PMID:19030233 NCBI chr 8:75,779,640...75,802,474
Ensembl chr 8:75,779,523...75,802,452
JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR1 protein]]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR2 protein]] CTD PMID:27779402 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO [Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of ATF4 mRNA] CTD PMID:31054322 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions ISO [Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of ATF6 mRNA] CTD PMID:31054322 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atp5me ATP synthase membrane subunit e multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of ATP5K mRNA] CTD PMID:19030233 NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013
JBrowse link
G Atrnl1 attractin like 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ATRNL1 mRNA] CTD PMID:19030233 NCBI chr 1:256,670,976...257,219,291
Ensembl chr 1:256,670,627...257,213,197
JBrowse link
G Aurkb aurora kinase B decreases expression ISO Rimonabant results in decreased expression of AURKB protein CTD PMID:19479993 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of BAX protein]] CTD PMID:30769029 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in decreased expression of BCL2 protein]]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of BCL2 protein] CTD PMID:26967640 PMID:30769029 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol results in increased expression of BDNF mRNA] CTD PMID:20929960 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of BRAF mRNA] CTD PMID:19030233 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of BZW1 mRNA] CTD PMID:19030233 NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430
JBrowse link
G C1galt1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of C1GALT1 mRNA] CTD PMID:19030233 NCBI chr 4:35,930,743...35,966,102
Ensembl chr 4:35,928,104...35,961,831
JBrowse link
G Cab39l calcium binding protein 39-like multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAB39L mRNA] CTD PMID:19030233 NCBI chr15:33,606,588...33,710,518
Ensembl chr15:33,606,694...33,743,545
JBrowse link
G Calm1 calmodulin 1 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CALM1 mRNA]
Rimonabant affects the expression of CALM1 mRNA
CTD PMID:19030233 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Canx calnexin multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CANX mRNA] CTD PMID:19030233 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Capn7 calpain 7 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAPN7 mRNA] CTD PMID:19030233 NCBI chr16:6,545,630...6,581,908
Ensembl chr16:6,545,731...6,581,905
JBrowse link
G Cartpt CART prepropeptide multiple interactions
increases response to substance
affects expression
ISO FAAH affects the reaction [Rimonabant affects the expression of CARTPT protein]
CARTPT results in increased susceptibility to Rimonabant
CTD PMID:16131814 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
JBrowse link
G Casp12 caspase 12 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CASP12 mRNA] CTD PMID:19030233 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp3 caspase 3 multiple interactions ISO Rimonabant inhibits the reaction [XLR-11 results in increased activity of CASP3 protein]
Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased cleavage of CASP3 protein]]; Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]]
CTD PMID:26209559 PMID:29410032 PMID:30769029 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cav1 caveolin 1 affects expression
multiple interactions
ISO Rimonabant affects the expression of CAV1 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAV1 mRNA]
CTD PMID:19030233 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cav2 caveolin 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAV2 mRNA] CTD PMID:19030233 NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244
JBrowse link
G Cavin1 caveolae associated protein 1 affects expression ISO Rimonabant affects the expression of CAVIN1 mRNA CTD PMID:19030233 NCBI chr10:85,884,100...85,896,136
Ensembl chr10:85,889,036...85,896,120
JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CCAR1 mRNA] CTD PMID:19030233 NCBI chr20:30,685,916...30,728,531
Ensembl chr20:30,685,916...30,728,526
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases expression
ISO
EXP
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CCL2]
Rimonabant results in decreased expression of CCL2 mRNA
CTD PMID:30365523 PMID:32832534 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CCL3] CTD PMID:32832534 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccnb1 cyclin B1 increases expression ISO Rimonabant results in increased expression of CCNB1 protein CTD PMID:19479993 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Rimonabant results in decreased expression of CCND1 protein CTD PMID:16822929 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 multiple interactions ISO Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of CCND2 protein] CTD PMID:26967640 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccng1 cyclin G1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CCNG1 mRNA] CTD PMID:19030233 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Ccpg1 cell cycle progression 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CCPG1 mRNA] CTD PMID:19030233 NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 multiple interactions ISO [Rimonabant co-treated with MIR762 mRNA] affects the expression of CCR7 mRNA CTD PMID:30910812 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
JBrowse link
G Cd36 CD36 molecule affects expression
multiple interactions
ISO Rimonabant affects the expression of CD36 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CD36 mRNA]
CTD PMID:19030233 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cdc73 cell division cycle 73 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CDC73 mRNA] CTD PMID:19030233 NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656
JBrowse link
G Cdk5 cyclin-dependent kinase 5 multiple interactions ISO Rimonabant inhibits the reaction [[Ethanol results in increased activity of CDK5 protein] which results in increased degradation of CDK5R1 protein]; Rimonabant inhibits the reaction [Ethanol results in increased activity of CDK5 protein] CTD PMID:30143782 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 multiple interactions ISO Rimonabant inhibits the reaction [[Ethanol results in increased activity of CDK5 protein] which results in increased degradation of CDK5R1 protein] CTD PMID:30143782 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
JBrowse link
G Cdkl2 cyclin dependent kinase like 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CDKL2 mRNA] CTD PMID:19030233 NCBI chr14:16,027,381...16,063,257
Ensembl chr14:16,028,363...16,063,252
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO Rimonabant results in increased expression of CDKN1B protein CTD PMID:16822929 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO Rimonabant inhibits the reaction [butylparaben results in increased expression of CEBPA mRNA] CTD PMID:27659731 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of CEBPD mRNA] CTD PMID:19030233 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Chd9 chromodomain helicase DNA binding protein 9 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CHD9 mRNA] CTD PMID:19030233 NCBI chr19:15,941,535...16,146,220
Ensembl chr19:15,942,687...16,164,556
JBrowse link
G Chek1 checkpoint kinase 1 decreases phosphorylation ISO Rimonabant results in decreased phosphorylation of CHEK1 protein CTD PMID:19479993 NCBI chr 8:36,420,565...36,443,477 JBrowse link
G Clic4 chloride intracellular channel 4 affects expression
multiple interactions
ISO Rimonabant affects the expression of CLIC4 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CLIC4 mRNA]
CTD PMID:19030233 NCBI chr 5:147,456,819...147,513,278
Ensembl chr 5:147,453,712...147,513,452
JBrowse link
G Cltc clathrin heavy chain multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CLTC mRNA] CTD PMID:19030233 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
JBrowse link
G Cnot1 CCR4-NOT transcription complex, subunit 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CNOT1 mRNA] CTD PMID:19030233 NCBI chr19:9,255,190...9,346,574
Ensembl chr19:9,255,194...9,346,574
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol results in increased expression of CNP protein] CTD PMID:32956517 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
decreases activity
affects localization
affects binding
decreases expression
ISO
EXP
1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea analog inhibits the reaction [Rimonabant binds to CNR1 protein]; 1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea inhibits the reaction [Rimonabant binds to CNR1 protein]; 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Rimonabant binds to CNR1 protein]; 5F-CUMYL-PICA inhibits the reaction [Rimonabant binds to CNR1 protein]; arachidonyl dopamine inhibits the reaction [Rimonabant binds to CNR1 protein]; Dronabinol inhibits the reaction [Rimonabant binds to CNR1 protein]; methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-methylbutanoate analog inhibits the reaction [Rimonabant binds to CNR1 protein]; methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-methylbutanoate inhibits the reaction [Rimonabant binds to CNR1 protein]; N'-((3Z)-1-(1-hexyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene)benzohydrazide affects the reaction [Rimonabant binds to CNR1 protein]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide inhibits the reaction [Rimonabant binds to CNR1 protein]; Rimonabant binds to and results in decreased activity of CNR1 protein; Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased activity of CNR1]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR1 protein]]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole results in increased activity of CNR1 protein]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] which results in increased abundance of Cyclic AMP]; Rimonabant inhibits the reaction [anandamide results in increased activity of CNR1]; Rimonabant inhibits the reaction [Dronabinol results in increased expression of CNR1 mRNA]; Rimonabant inhibits the reaction [HU 211 results in increased activity of CNR1]
Rimonabant results in decreased activity of CNR1 protein
Rimonabant affects the localization of CNR1 protein
Rimonabant results in decreased expression of CNR1 mRNA
[Rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone; [Rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to palmidrol analog; Cannabidiol inhibits the reaction [Poly I-C inhibits the reaction [Rimonabant binds to CNR1 protein]]; Poly I-C inhibits the reaction [Rimonabant binds to CNR1 protein]; Rimonabant binds to and results in decreased activity of CNR1 protein; Rimonabant inhibits the reaction [1-(5-fluoropentyl)-3-(1-naphthoyl)indole analog binds to CNR1 protein]; Rimonabant inhibits the reaction [1-(5-fluoropentyl)-3-(1-naphthoyl)indole binds to CNR1 protein]; Rimonabant inhibits the reaction [[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [IFNG protein affects the reaction [Lipopolysaccharides results in increased abundance of Nitric Oxide]]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] which results in decreased abundance of Nitric Oxide]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of CNR1 protein]
6-methyl-3-(2-nitro-1-(thiophen-2-yl)propyl)-2-phenyl-1H-indole inhibits the reaction [Rimonabant binds to CNR1 protein]; [Rimonabant binds to and results in decreased activity of CNR1 protein] which affects the expression of FOS protein; [Rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to Nicotine; Rimonabant binds to and results in decreased activity of CNR1 protein; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CNR1 mRNA]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased transport of Nitric Oxide]]; Rimonabant inhibits the reaction [[anandamide binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased transport of Nitric Oxide]]; Rimonabant inhibits the reaction [HU 211 binds to and results in increased activity of CNR1 protein]
CTD PMID:10027878 PMID:10422789 PMID:10871313 PMID:11517236 PMID:11558437 More... NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions ISO Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR2 protein]]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole results in increased activity of CNR2 protein] CTD PMID:27779402 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression EXP Rimonabant results in decreased expression of COL1A1 mRNA CTD PMID:21863215 PMID:30365523 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Copg2 COPI coat complex subunit gamma 2 affects expression
multiple interactions
ISO Rimonabant affects the expression of COPG2 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of COPG2 mRNA]
CTD PMID:19030233 NCBI chr 4:59,366,086...59,501,591
Ensembl chr 4:59,366,086...59,501,618
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP Rimonabant results in increased expression of CPT1A mRNA CTD PMID:30365523 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP
ISO
Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of CREB1 protein]
Rimonabant inhibits the reaction [Dronabinol results in decreased expression of and results in decreased phosphorylation of CREB1 protein]
CTD PMID:15913574 PMID:19912468 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Creb3l2 cAMP responsive element binding protein 3-like 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CREB3L2 mRNA] CTD PMID:19030233 NCBI chr 4:65,907,570...66,112,078
Ensembl chr 4:65,907,655...66,023,763
JBrowse link
G Crh corticotropin releasing hormone decreases expression
multiple interactions
EXP Rimonabant results in decreased expression of CRH mRNA
Dronabinol affects the reaction [Rimonabant results in decreased expression of CRH mRNA]; Rimonabant inhibits the reaction [HU 211 results in decreased expression of CRH mRNA]
CTD PMID:12968131 PMID:15099659 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Csde1 cold shock domain containing E1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CSDE1 mRNA] CTD PMID:19030233 NCBI chr 2:190,546,015...190,582,790
Ensembl chr 2:190,554,980...190,582,784
JBrowse link
G Cul1 cullin 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CUL1 mRNA] CTD PMID:19030233 NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980
JBrowse link
G Cul3 cullin 3 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CUL3 mRNA] CTD PMID:19030233 NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462
JBrowse link
G Cxadr CXADR, Ig-like cell adhesion molecule multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CXADR mRNA] CTD PMID:19030233 NCBI chr11:16,982,752...17,030,078
Ensembl chr11:16,982,860...17,030,046
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CXCL10] CTD PMID:32832534 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CXCL1] CTD PMID:32832534 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cyp4v3 cytochrome P450, family 4, subfamily v, polypeptide 3 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CYP4V3 mRNA] CTD PMID:19030233 NCBI chr16:46,917,929...46,958,735
Ensembl chr16:46,918,401...46,943,395
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO [Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of DDIT3 mRNA] CTD PMID:31054322 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddx27 DEAD-box helicase 27 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of DDX27 mRNA] CTD PMID:19030233 NCBI chr 3:155,744,182...155,763,380
Ensembl chr 3:155,744,150...155,763,372
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DDX3X mRNA] CTD PMID:19030233 NCBI chr  X:9,479,532...9,493,455
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DNAJC10 mRNA] CTD PMID:19030233 NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
JBrowse link
G Dpp4 dipeptidylpeptidase 4 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DPP4 mRNA] CTD PMID:19030233 NCBI chr 3:46,962,243...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Dr1 down-regulator of transcription 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DR1 mRNA] CTD PMID:19030233 NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638
JBrowse link
G Dync1i2 dynein cytoplasmic 1 intermediate chain 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DYNC1I2 mRNA] CTD PMID:19030233 NCBI chr 3:56,033,882...56,085,080
Ensembl chr 3:56,033,917...56,085,080
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EDEM1 mRNA] CTD PMID:19030233 NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
JBrowse link
G Efna5 ephrin A5 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EFNA5 mRNA] CTD PMID:19030233 NCBI chr 9:102,316,753...102,595,480
Ensembl chr 9:102,320,295...102,597,413
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 multiple interactions ISO Rimonabant inhibits the reaction [Ethanol promotes the reaction [EHMT2 protein binds to RAC1 promoter]] CTD PMID:30143782 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EIF4G2 mRNA] CTD PMID:19030233 NCBI chr 1:165,181,433...165,193,583
Ensembl chr 1:165,181,434...165,193,588
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EIF5 mRNA] CTD PMID:19030233
G Ell2 elongation factor for RNA polymerase II 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ELL2 mRNA] CTD PMID:19030233 NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781
JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EPS15 mRNA] CTD PMID:19030233 NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221
JBrowse link
G Ermp1 endoplasmic reticulum metallopeptidase 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ERMP1 mRNA] CTD PMID:19030233 NCBI chr 1:227,383,992...227,422,120
Ensembl chr 1:227,387,920...227,436,909
JBrowse link
G Faah fatty acid amide hydrolase multiple interactions EXP
ISO
[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Rimonabant] affects the expression of FAAH mRNA
FAAH affects the reaction [Rimonabant affects the expression of CARTPT protein]; Rimonabant inhibits the reaction [FAAH gene mutant form results in increased susceptibility to anandamide]
CTD PMID:16131814 PMID:27385208 PMID:32833042 NCBI chr 5:129,479,774...129,499,018 JBrowse link
G Faahl fatty-acid amide hydrolase-like multiple interactions ISO FAAH affects the reaction [Rimonabant affects the expression of CARTPT protein]; Rimonabant inhibits the reaction [FAAH gene mutant form results in increased susceptibility to anandamide] CTD PMID:16131814 PMID:27385208
G Fam126b family with sequence similarity 126, member B affects expression ISO Rimonabant affects the expression of FAM126B mRNA CTD PMID:19030233 NCBI chr 9:60,056,883...60,129,176
Ensembl chr 9:60,056,890...60,093,007
JBrowse link
G Fam199x family with sequence similarity 199, X-linked multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FAM199X mRNA] CTD PMID:19030233 NCBI chr  X:100,384,502...100,413,150
Ensembl chr  X:100,384,225...100,414,938
JBrowse link
G Far1 fatty acyl CoA reductase 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FAR1 mRNA] CTD PMID:19030233 NCBI chr 1:167,644,622...167,705,868
Ensembl chr 1:167,644,677...167,705,730
JBrowse link
G Fasn fatty acid synthase decreases expression
multiple interactions
ISO Rimonabant results in decreased expression of FASN mRNA
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of FASN mRNA]
CTD PMID:19030233 PMID:20110567 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbxl5 F-box and leucine-rich repeat protein 5 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FBXL5 mRNA] CTD PMID:19030233 NCBI chr14:67,305,109...67,347,383
Ensembl chr14:67,267,801...67,347,383
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of FBXW7 mRNA] CTD PMID:19030233 NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Fem1a fem-1 homolog A multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of FEM1A mRNA] CTD PMID:19030233 NCBI chr 9:1,091,695...1,093,901
Ensembl chr 9:1,090,527...1,100,628
JBrowse link
G Fermt2 FERM domain containing kindlin 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FERMT2 mRNA] CTD PMID:19030233 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811
JBrowse link
G Fgf1 fibroblast growth factor 1 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FGF1 mRNA]
Rimonabant affects the expression of FGF1 mRNA
CTD PMID:19030233 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fmr1 FMRP translational regulator 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FMR1 mRNA] CTD PMID:19030233 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050
JBrowse link
G Fndc3b fibronectin type III domain containing 3B multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FNDC3B mRNA] CTD PMID:19030233 NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP
ISO
Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOS protein]
[Rimonabant binds to and results in decreased activity of CNR1 protein] which affects the expression of FOS protein; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of FOS protein]
CTD PMID:9751146 PMID:12560108 PMID:15280883 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOSB protein] CTD PMID:9751146 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions EXP Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOSL1 protein] CTD PMID:9751146 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit multiple interactions EXP Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOSL2 protein] CTD PMID:9751146 NCBI chr 6:24,297,898...24,319,157
Ensembl chr 6:24,300,956...24,320,034
JBrowse link
G Frmd4b FERM domain containing 4B multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FRMD4B mRNA] CTD PMID:19030233 NCBI chr 4:129,895,401...130,222,070
Ensembl chr 4:129,895,708...130,084,197
JBrowse link
G G6pc3 glucose 6 phosphatase catalytic subunit 3 increases expression ISO Rimonabant results in increased expression of G6PC3 mRNA CTD PMID:20110567 NCBI chr10:87,146,987...87,151,223
Ensembl chr10:87,146,901...87,151,221
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO Rimonabant results in increased expression of GAPDH mRNA CTD PMID:16282221 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression ISO Rimonabant results in decreased expression of GFAP protein CTD PMID:21373835 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Ggps1 geranylgeranyl diphosphate synthase 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GGPS1 mRNA] CTD PMID:19030233 NCBI chr17:51,263,262...51,282,471
Ensembl chr17:51,263,263...51,276,220
JBrowse link
G Gls glutaminase multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GLS mRNA] CTD PMID:19030233 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
JBrowse link
G Gmfb glia maturation factor, beta multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GMFB mRNA] CTD PMID:19030233 NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 decreases expression ISO Rimonabant results in decreased expression of GPLD1 mRNA CTD PMID:20110567 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
JBrowse link
G Gpr55 G protein-coupled receptor 55 multiple interactions ISO Rimonabant binds to and results in increased activity of GPR55 protein CTD PMID:17876302 NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613
JBrowse link
G Gpt glutamic--pyruvic transaminase decreases expression EXP
ISO
Rimonabant results in decreased expression of GPT protein CTD PMID:28705172 PMID:30365523 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Grb14 growth factor receptor bound protein 14 affects expression
multiple interactions
ISO Rimonabant affects the expression of GRB14 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GRB14 mRNA]
CTD PMID:19030233 NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIA1]
Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIA1 mRNA]
CTD PMID:19912468 PMID:29230395 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIN2A] CTD PMID:19912468 NCBI chr10:5,630,684...6,043,341
Ensembl chr10:5,631,369...6,044,637
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIN2B] CTD PMID:19912468 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression EXP Rimonabant results in increased expression of GSTA1 mRNA CTD PMID:30365523 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Hdhd2 haloacid dehalogenase-like hydrolase domain containing 2 affects expression ISO Rimonabant affects the expression of HDHD2 mRNA CTD PMID:19030233 NCBI chr18:70,475,037...70,526,471
Ensembl chr18:70,474,926...70,526,470
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of HIF1A mRNA] CTD PMID:19030233 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hipk3 homeodomain interacting protein kinase 3 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of HIPK3 mRNA] CTD PMID:19030233 NCBI chr 3:90,796,980...90,866,701
Ensembl chr 3:90,800,296...90,867,759
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP Rimonabant results in increased expression of HMOX1 mRNA; Rimonabant results in increased expression of HMOX1 protein CTD PMID:30365523 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases activity ISO Rimonabant results in decreased activity of HNF4A protein CTD PMID:31981244 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of HSP90AA1 mRNA] CTD PMID:19030233 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of HSPA5 mRNA] CTD PMID:31054322 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression
multiple interactions
ISO Rimonabant results in decreased expression of ICAM1 protein
Rimonabant inhibits the reaction [Glucose results in increased expression of ICAM1 protein]
CTD PMID:21373835 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma multiple interactions EXP Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [IFNG protein affects the reaction [Lipopolysaccharides results in increased abundance of Nitric Oxide]]] CTD PMID:11727767 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IGF1 mRNA] CTD PMID:19030233 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 affects expression
multiple interactions
ISO Rimonabant affects the expression of IGFBP5 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IGFBP5 mRNA]
CTD PMID:19030233 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Il10 interleukin 10 multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL10 protein]] CTD PMID:32385136 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol results in decreased expression of IL12RB2 mRNA] CTD PMID:14741435 PMID:18792785 NCBI chr 4:96,424,615...96,515,327
Ensembl chr 4:96,426,842...96,515,289
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Rimonabant co-treated with SR 144528] inhibits the reaction [OMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of IL1B]; Rimonabant inhibits the reaction [OMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; Rimonabant promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:15748152 PMID:32832534 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of IL6] CTD PMID:32832534 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins2 insulin 2 decreases expression ISO Rimonabant results in decreased expression of INS protein CTD PMID:20110567 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Ipo11 importin 11 affects expression
multiple interactions
ISO Rimonabant affects the expression of IPO11 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IPO11 mRNA]
CTD PMID:19030233 NCBI chr 2:38,169,688...38,342,929 JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IQGAP1 mRNA]
Rimonabant affects the expression of IQGAP1 mRNA
CTD PMID:19030233 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
JBrowse link
G Irf5 interferon regulatory factor 5 multiple interactions ISO Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of IRF5] CTD PMID:32832534 NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267
JBrowse link
G Itgam integrin subunit alpha M decreases expression EXP Rimonabant results in decreased expression of ITGAM mRNA CTD PMID:30365523 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgav integrin subunit alpha V multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ITGAV mRNA] CTD PMID:19030233 NCBI chr 3:68,838,524...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ITGB1 mRNA] CTD PMID:19030233 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ITPR2 mRNA] CTD PMID:19030233 NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164
JBrowse link
G Ivns1abp influenza virus NS1A binding protein multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IVNS1ABP mRNA] CTD PMID:19030233 NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
JBrowse link
G Kif5b kinesin family member 5B multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KIF5B mRNA] CTD PMID:19030233 NCBI chr17:51,489,873...51,527,508
Ensembl chr17:51,489,944...51,527,508
JBrowse link
G Klf4 Kruppel like factor 4 increases expression
multiple interactions
ISO Rimonabant results in increased expression of KLF4 mRNA
MIR466J mRNA affects the reaction [Rimonabant results in increased expression of KLF4 mRNA]; Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of KLF4 mRNA]
CTD PMID:30910812 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Klf6 Kruppel-like factor 6 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KLF6 mRNA] CTD PMID:19030233 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
JBrowse link
G Klhl9 kelch-like family member 9 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KLHL9 mRNA] CTD PMID:19030233 NCBI chr 5:103,333,747...103,337,931 JBrowse link
G Kpna3 karyopherin subunit alpha 3 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KPNA3 mRNA] CTD PMID:19030233 NCBI chr15:35,536,310...35,610,066
Ensembl chr15:35,536,316...35,610,419
JBrowse link
G Kpnb1 karyopherin subunit beta 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KPNB1 mRNA] CTD PMID:19030233 NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LAMP2 mRNA] CTD PMID:19030233 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Large1 LARGE xylosyl- and glucuronyltransferase 1 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LARGE1 mRNA]
Rimonabant affects the expression of LARGE1 mRNA
CTD PMID:19030233 NCBI chr19:11,603,129...12,048,930
Ensembl chr19:11,603,129...12,048,930
JBrowse link
G Lep leptin multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased secretion of LEP protein]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of BCL2 protein]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of CCND2 protein]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of INS1 protein] CTD PMID:19030233 PMID:26967640 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP Rimonabant inhibits the reaction [Dronabinol results in decreased expression of LHB protein] CTD PMID:9825732 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Lipc lipase C, hepatic type increases expression ISO Rimonabant results in increased expression of LIPC mRNA CTD PMID:20110567 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lipe lipase E, hormone sensitive type affects expression ISO Rimonabant affects the expression of LIPE mRNA CTD PMID:20110567 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
JBrowse link
G Lmo1 LIM domain only 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LMO1 mRNA] CTD PMID:19030233 NCBI chr 1:163,132,338...163,168,521
Ensembl chr 1:163,132,339...163,168,522
JBrowse link
G LOC498453 similar to transcription elongation factor A 1 isoform 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of TCEA1 mRNA] CTD PMID:19030233 NCBI chr15:10,401,012...10,403,460 JBrowse link
G Lpgat1 lysophosphatidylglycerol acyltransferase 1 affects expression ISO Rimonabant affects the expression of LPGAT1 mRNA CTD PMID:19030233 NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333
JBrowse link
G Lrrfip1 LRR binding FLII interacting protein 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LRRFIP1 mRNA] CTD PMID:19030233 NCBI chr 9:91,592,032...91,720,250
Ensembl chr 9:91,643,197...91,720,250
JBrowse link
G Mag myelin-associated glycoprotein multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol results in increased expression of MAG protein] CTD PMID:32956517 NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO Rimonabant results in increased expression of and results in increased lipidation of MAP1LC3B protein CTD PMID:31570772 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
affects localization
decreases activity
ISO
EXP
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [methanandamide results in increased phosphorylation of MAPK1 protein]
Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in decreased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]
Rimonabant affects the localization of MAPK1 protein
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of MAPK1 protein]
Rimonabant results in decreased activity of MAPK1 protein
CTD PMID:8526880 PMID:11553284 PMID:12657697 PMID:12834810 PMID:16282221 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases activity
affects localization
ISO
EXP
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of MAPK3 protein]
Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in decreased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]
Rimonabant results in decreased activity of MAPK3 protein
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [methanandamide results in increased phosphorylation of MAPK3 protein]
Rimonabant affects the localization of MAPK3 protein
CTD PMID:8526880 PMID:11553284 PMID:12657697 PMID:12834810 PMID:16282221 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK8 protein]; Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of MAPK8 protein] CTD PMID:18950629 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Marchf6 membrane associated ring-CH-type finger 6 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MARCHF6 mRNA] CTD PMID:19030233 NCBI chr 2:82,455,686...82,532,917
Ensembl chr 2:82,455,689...82,532,910
JBrowse link
G Mbnl1 muscleblind-like splicing regulator 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MBNL1 mRNA] CTD PMID:19030233 NCBI chr 2:144,639,819...144,814,395
Ensembl chr 2:144,670,285...144,814,368
JBrowse link
G Mbnl2 muscleblind-like splicing regulator 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MBNL2 mRNA] CTD PMID:19030233 NCBI chr15:97,385,238...97,542,924
Ensembl chr15:97,385,244...97,542,937
JBrowse link
G Mest mesoderm specific transcript affects expression
multiple interactions
ISO Rimonabant affects the expression of MEST mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MEST mRNA]
CTD PMID:19030233 NCBI chr 4:59,354,445...59,364,919
Ensembl chr 4:59,354,447...59,366,145
JBrowse link
G Mgll monoglyceride lipase affects response to substance ISO MGLL protein affects the susceptibility to Rimonabant CTD PMID:21911610 NCBI chr 4:121,192,187...121,294,187
Ensembl chr 4:121,192,195...121,294,179
JBrowse link
G Mir16 microRNA 16 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of MIR16 mRNA] CTD PMID:19030233 NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443
JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase multiple interactions ISO Rimonabant inhibits the reaction [Quetiapine Fumarate affects the localization of MLKL protein]; Rimonabant inhibits the reaction [Quetiapine Fumarate results in increased expression of and results in increased phosphorylation of MLKL protein] CTD PMID:31220554 NCBI chr19:39,278,123...39,304,555
Ensembl chr19:39,276,785...39,304,502
JBrowse link
G Mmp13 matrix metallopeptidase 13 decreases expression EXP Rimonabant results in decreased expression of MMP13 mRNA CTD PMID:21863215 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mog myelin oligodendrocyte glycoprotein multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol results in increased expression of MOG protein] CTD PMID:32956517 NCBI chr20:1,513,137...1,523,473
Ensembl chr20:1,513,239...1,523,474
JBrowse link
G Mospd1 motile sperm domain containing 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MOSPD1 mRNA] CTD PMID:19030233 NCBI chr  X:133,100,200...133,127,960
Ensembl chr  X:133,100,422...133,127,908
JBrowse link
G Mycbp2 MYC binding protein 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MYCBP2 mRNA] CTD PMID:19030233 NCBI chr15:79,937,354...80,175,432
Ensembl chr15:79,937,354...80,175,498
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NAP1L1 mRNA] CTD PMID:19030233 NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
JBrowse link
G Napepld N-acyl phosphatidylethanolamine phospholipase D multiple interactions EXP [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Rimonabant] affects the expression of NAPEPLD mRNA CTD PMID:32833042 NCBI chr 4:13,360,532...13,398,815
Ensembl chr 4:13,361,006...13,398,748
JBrowse link
G Ncl nucleolin multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NCL mRNA] CTD PMID:19030233 NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136
JBrowse link
G Ndc1 NDC1 transmembrane nucleoporin affects expression ISO Rimonabant affects the expression of NDC1 mRNA CTD PMID:19030233 NCBI chr 5:122,155,992...122,202,295
Ensembl chr 5:122,155,967...122,202,291
JBrowse link
G Ndufb11 NADH:ubiquinone oxidoreductase subunit B11 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of NDUFB11 mRNA] CTD PMID:19030233 NCBI chr  X:1,572,805...1,575,063
Ensembl chr  X:1,572,785...1,575,062
JBrowse link
G Ndufb9 NADH:ubiquinone oxidoreductase subunit B9 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of NDUFB9 mRNA]
Rimonabant affects the expression of NDUFB9 mRNA
CTD PMID:19030233 NCBI chr 7:90,481,013...90,487,360 JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of NDUFS8 mRNA] CTD PMID:19030233 NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NEDD4 mRNA] CTD PMID:19030233 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
JBrowse link
G Nek7 NIMA-related kinase 7 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NEK7 mRNA]
Rimonabant affects the expression of NEK7 mRNA
CTD PMID:19030233 NCBI chr13:50,022,212...50,149,374
Ensembl chr13:50,022,218...50,149,296
JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NFATC3 mRNA] CTD PMID:19030233 NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression EXP Rimonabant results in increased expression of NFE2L2 mRNA CTD PMID:30365523 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nid1 nidogen 1 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NID1 mRNA]
Rimonabant affects the expression of NID1 mRNA
CTD PMID:19030233 NCBI chr17:86,085,046...86,158,277
Ensembl chr17:86,085,077...86,158,267
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of NLRP3] CTD PMID:32832534 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO [Rimonabant co-treated with SR 144528] inhibits the reaction [OMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NOS2]; Rimonabant promotes the reaction [PF 3845 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]] CTD PMID:15748152 PMID:30910812 PMID:31121907 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Npr3 natriuretic peptide receptor 3 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NPR3 mRNA]
Rimonabant affects the expression of NPR3 mRNA
CTD PMID:19030233 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP Rimonabant results in increased expression of NQO1 mRNA; Rimonabant results in increased expression of NQO1 protein CTD PMID:30365523 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NR3C1 mRNA] CTD PMID:19030233 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Ntn1 netrin 1 multiple interactions
decreases expression
ISO Rimonabant affects the reaction [Dietary Fats affects the expression of NTN1 protein]; Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NTN1 mRNA]; Rimonabant inhibits the reaction [MIR762 mRNA results in increased expression of NTN1 mRNA]
Rimonabant results in decreased expression of NTN1 mRNA
CTD PMID:30910812 NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of OPA1 mRNA] CTD PMID:19030233 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Osbpl8 oxysterol binding protein-like 8 affects expression
multiple interactions
ISO Rimonabant affects the expression of OSBPL8 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of OSBPL8 mRNA]
CTD PMID:19030233 NCBI chr 7:46,596,944...46,749,888
Ensembl chr 7:46,596,983...46,749,888
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression ISO Rimonabant results in decreased expression of PARP1 protein CTD PMID:19479993 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pc pyruvate carboxylase multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PCX mRNA] CTD PMID:19030233 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 increases expression ISO Rimonabant results in increased expression of PCK1 mRNA CTD PMID:20110567 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pcyox1 prenylcysteine oxidase 1 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PCYOX1 mRNA]
Rimonabant affects the expression of PCYOX1 mRNA
CTD PMID:19030233 NCBI chr 4:118,832,114...118,842,951
Ensembl chr 4:118,830,638...118,842,951
JBrowse link
G Phip pleckstrin homology domain interacting protein multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PHIP mRNA] CTD PMID:19030233 NCBI chr 8:83,776,802...83,891,192
Ensembl chr 8:83,781,465...83,894,283
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha affects expression
multiple interactions
ISO Rimonabant affects the expression of PIK3CA mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PIK3CA mRNA]
CTD PMID:19030233 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Plac8 placenta associated 8 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PLAC8 mRNA] CTD PMID:19030233 NCBI chr14:9,052,601...9,074,264
Ensembl chr14:9,063,048...9,074,264
JBrowse link
G Plekha1 pleckstrin homology domain containing A1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PLEKHA1 mRNA] CTD PMID:19030233 NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156
JBrowse link
G Plin2 perilipin 2 decreases expression
multiple interactions
ISO Rimonabant results in decreased expression of PLIN2 protein
Rimonabant inhibits the reaction [Oleic Acid results in increased expression of PLIN2 protein]
CTD PMID:31570772 NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Pmm1 phosphomannomutase 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PMM1 mRNA] CTD PMID:19030233 NCBI chr 7:113,466,632...113,477,004
Ensembl chr 7:113,466,632...113,477,022
JBrowse link
G Pold2 DNA polymerase delta 2, accessory subunit multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of POLD2 mRNA] CTD PMID:19030233 NCBI chr14:80,748,971...80,755,188
Ensembl chr14:80,748,974...80,755,160
JBrowse link
G Polr2j RNA polymerase II subunit J multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of POLR2J mRNA] CTD PMID:19030233 NCBI chr12:20,543,038...20,548,590
Ensembl chr12:20,543,038...20,548,594
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression EXP Rimonabant results in increased expression of PPARA mRNA CTD PMID:30365523 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects expression ISO Rimonabant affects the expression of PPARG mRNA CTD PMID:20110567 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppfibp1 PPFIA binding protein 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PPFIBP1 mRNA] CTD PMID:19030233 NCBI chr 4:179,807,579...179,951,428
Ensembl chr 4:179,808,794...179,951,428
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PPP1CB mRNA] CTD PMID:19030233 NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PPP3CA mRNA] CTD PMID:19030233 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Prkd3 protein kinase D3 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PRKD3 mRNA]
Rimonabant affects the expression of PRKD3 mRNA
CTD PMID:19030233 NCBI chr 6:16,032,507...16,108,444
Ensembl chr 6:16,032,585...16,108,443
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase decreases response to substance
multiple interactions
ISO
EXP
PRKN results in decreased susceptibility to Rimonabant
Rimonabant affects the reaction [PRKN mutant form affects the activity of TH protein]
CTD PMID:15882845 NCBI chr 1:48,688,651...49,882,520 JBrowse link
G Prl prolactin multiple interactions
increases expression
ISO
EXP
Rimonabant inhibits the reaction [Dronabinol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of PRL mRNA]]
Dronabinol affects the reaction [Rimonabant results in increased expression of PRL protein]; Rimonabant inhibits the reaction [Dronabinol results in decreased expression of PRL protein]
CTD PMID:9825732 PMID:15099659 PMID:31154070 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Prpf40a pre-mRNA processing factor 40 homolog A multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PRPF40A mRNA] CTD PMID:19030233 NCBI chr 3:37,625,585...37,689,859
Ensembl chr 3:37,627,690...37,690,886
JBrowse link
G Prps1 phosphoribosyl pyrophosphate synthetase 1 affects expression
multiple interactions
ISO Rimonabant affects the expression of PRPS1 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PRPS1 mRNA]
CTD PMID:19030233 NCBI chr  X:104,132,139...104,154,191
Ensembl chr  X:104,132,141...104,154,187
JBrowse link
G Ptbp3 polypyrimidine tract binding protein 3 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PTBP3 mRNA] CTD PMID:19030233 NCBI chr 5:74,313,536...74,399,439
Ensembl chr 5:74,315,101...74,399,791
JBrowse link
G Pten phosphatase and tensin homolog affects expression
multiple interactions
EXP Rimonabant affects the expression of PTEN mRNA
[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Rimonabant] affects the expression of PTEN mRNA
CTD PMID:32833042 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptges2 prostaglandin E synthase 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PTGES2 mRNA] CTD PMID:19030233 NCBI chr 3:15,690,501...15,697,688
Ensembl chr 3:15,690,501...15,697,688
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of PTGS2 protein]]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]] CTD PMID:26209559 PMID:30769029 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PTP4A1 mRNA] CTD PMID:19030233 NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964
JBrowse link
G Pyy peptide YY multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PYY mRNA] CTD PMID:19030233 NCBI chr10:87,061,155...87,062,278
Ensembl chr10:87,061,161...87,061,815
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO Rimonabant inhibits the reaction [Ethanol promotes the reaction [EHMT2 protein binds to RAC1 promoter]]; Rimonabant inhibits the reaction [Ethanol results in decreased expression of RAC1 protein] CTD PMID:30143782 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol results in increased localization of RAF1 protein]; Rimonabant inhibits the reaction [methanandamide results in increased localization of RAF1 protein] CTD PMID:12834810 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Ramp2 receptor activity modifying protein 2 affects expression
multiple interactions
ISO Rimonabant affects the expression of RAMP2 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RAMP2 mRNA]
CTD PMID:19030233 NCBI chr10:86,187,366...86,190,692 JBrowse link
G Rbms1 RNA binding motif, single stranded interacting protein 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RBMS1 mRNA] CTD PMID:19030233 NCBI chr 3:45,195,828...45,420,406
Ensembl chr 3:45,197,972...45,420,376
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RBPJ mRNA] CTD PMID:19030233 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases expression
ISO Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]
Rimonabant results in decreased expression of RELA protein
CTD PMID:21373835 PMID:26209559 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rfng RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RFNG mRNA]
Rimonabant affects the expression of RFNG mRNA
CTD PMID:19030233 NCBI chr10:106,047,221...106,050,331
Ensembl chr10:106,047,221...106,050,345
JBrowse link
G Rgs11 regulator of G-protein signaling 11 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RGS11 mRNA] CTD PMID:19030233 NCBI chr10:15,222,803...15,231,060
Ensembl chr10:15,222,803...15,231,060
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 multiple interactions ISO Rimonabant inhibits the reaction [Quetiapine Fumarate results in increased expression of RIPK1 protein] CTD PMID:31220554 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 multiple interactions ISO Rimonabant inhibits the reaction [Quetiapine Fumarate results in increased expression of RIPK3 protein] CTD PMID:31220554 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
JBrowse link
G rnf141 ring finger protein 141 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF141 mRNA] CTD PMID:19030233 NCBI chr 1:164,933,972...164,957,081
Ensembl chr 1:164,931,077...164,957,118
JBrowse link
G Rnf185 ring finger protein 185 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RNF185 mRNA] CTD PMID:19030233 NCBI chr14:78,292,517...78,329,832
Ensembl chr14:78,292,516...78,329,864
JBrowse link
G Rnf19a ring finger protein 19A, RBR E3 ubiquitin protein ligase multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF19A mRNA] CTD PMID:19030233 NCBI chr 7:67,425,833...67,465,214
Ensembl chr 7:67,425,837...67,465,222
JBrowse link
G Rnf2 ring finger protein 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF2 mRNA] CTD PMID:19030233 NCBI chr13:63,553,964...63,584,047
Ensembl chr13:63,554,862...63,583,099
JBrowse link
G Rnf6 ring finger protein 6 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF6 mRNA] CTD PMID:19030233 NCBI chr12:8,816,777...8,826,870
Ensembl chr12:8,816,833...8,826,847
JBrowse link
G Rp9 RP9, pre-mRNA splicing factor multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RP9 mRNA] CTD PMID:19030233 NCBI chr 8:20,955,447...21,005,225
Ensembl chr 8:20,941,362...21,005,175
JBrowse link
G Rpf2 ribosome production factor 2 homolog multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPF2 mRNA] CTD PMID:19030233 NCBI chr20:43,630,003...43,651,477
Ensembl chr20:43,629,951...43,651,509
JBrowse link
G Rpl18 ribosomal protein L18 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPL18 mRNA] CTD PMID:19030233 NCBI chr 1:96,188,811...96,191,452
Ensembl chr 1:96,188,112...96,191,452
JBrowse link
G Rpl28 ribosomal protein L28 affects expression
multiple interactions
ISO Rimonabant affects the expression of RPL28 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPL28 mRNA]
CTD PMID:19030233 NCBI chr 1:69,052,148...69,054,735
Ensembl chr 1:69,053,203...69,055,032
JBrowse link
G Rpl41 ribosomal protein L41 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPL41 mRNA] CTD PMID:19030233 NCBI chr 7:977,885...978,965 JBrowse link
G Rps10 ribosomal protein S10 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPS10 mRNA] CTD PMID:19030233 NCBI chr20:5,694,313...5,698,922
Ensembl chr20:5,694,313...5,699,044
JBrowse link
G Rps15 ribosomal protein S15 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPS15 mRNA] CTD PMID:19030233 NCBI chr 7:9,416,003...9,417,442
Ensembl chr 7:9,416,004...9,417,450
JBrowse link
G Rps28 ribosomal protein S28 affects expression ISO Rimonabant affects the expression of RPS28 mRNA CTD PMID:19030233 NCBI chr 7:14,607,801...14,609,170
Ensembl chr 7:14,607,801...14,609,170
JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation ISO Rimonabant results in decreased phosphorylation of RPS6 protein CTD PMID:30687088 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Rps8 ribosomal protein S8 affects expression
multiple interactions
ISO Rimonabant affects the expression of RPS8 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPS8 mRNA]
CTD PMID:19030233 NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268
JBrowse link
G Rras2 RAS related 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RRAS2 mRNA] CTD PMID:19030233 NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111
JBrowse link
G Rxrb retinoid X receptor beta multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RXRB mRNA] CTD PMID:19030233 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
JBrowse link
G Ryk receptor-like tyrosine kinase affects expression
multiple interactions
ISO Rimonabant affects the expression of RYK mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RYK mRNA]
CTD PMID:19030233 NCBI chr 8:103,419,348...103,492,083
Ensembl chr 8:103,419,275...103,491,698
JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression ISO Rimonabant results in increased expression of SCARB1 mRNA CTD PMID:20110567 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO Rimonabant results in decreased expression of SCD1 mRNA CTD PMID:20110567 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SCD2 mRNA] CTD PMID:19030233 NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232
JBrowse link
G Scoc short coiled-coil protein multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SCOC mRNA] CTD PMID:19030233 NCBI chr19:24,659,651...24,689,236
Ensembl chr19:24,659,651...24,693,217
JBrowse link
G Sec62 SEC62 homolog, preprotein translocation factor multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEC62 mRNA] CTD PMID:19030233 NCBI chr 2:112,570,810...112,607,576
Ensembl chr 2:112,570,819...112,601,814
JBrowse link
G Sec63 SEC63 homolog, protein translocation regulator multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEC63 mRNA] CTD PMID:19030233 NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055
JBrowse link
G Sema3c semaphorin 3C multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEMA3C mRNA] CTD PMID:19030233 NCBI chr 4:17,583,212...17,747,234
Ensembl chr 4:17,583,212...17,746,534
JBrowse link
G Sepsecs Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase affects expression ISO Rimonabant affects the expression of SEPSECS mRNA CTD PMID:19030233 NCBI chr14:58,311,484...58,341,745
Ensembl chr14:58,311,499...58,341,740
JBrowse link
G Septin2 septin 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEPTIN2 mRNA] CTD PMID:19030233 NCBI chr 9:94,018,141...94,051,386
Ensembl chr 9:94,018,208...94,051,386
JBrowse link
G Septin6 septin 6 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SEPTIN6 mRNA] CTD PMID:19030233 NCBI chr  X:116,153,255...116,230,334
Ensembl chr  X:116,153,255...116,230,115
JBrowse link
G Serpinb6a serpin family B member 6A multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SERPINB6A mRNA]
Rimonabant affects the expression of SERPINB6A mRNA
CTD PMID:19030233 NCBI chr17:30,871,428...30,989,703
Ensembl chr17:30,871,468...31,014,427
JBrowse link
G Serpine1 serpin family E member 1 decreases expression EXP Rimonabant results in decreased expression of SERPINE1 protein CTD PMID:17882151 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sestd1 SEC14 and spectrin domain containing 1 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SESTD1 mRNA]
Rimonabant affects the expression of SESTD1 mRNA
CTD PMID:19030233 NCBI chr 3:62,123,590...62,220,759
Ensembl chr 3:62,129,887...62,220,546
JBrowse link
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SGTA mRNA] CTD PMID:19030233 NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458
JBrowse link
G Sh3bgrl SH3 domain binding glutamate-rich protein like multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SH3BGRL mRNA] CTD PMID:19030233 NCBI chr  X:74,167,029...74,263,783
Ensembl chr  X:74,166,871...74,263,783
JBrowse link
G Sipa1l1 signal-induced proliferation-associated 1 like 1 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SIPA1L1 mRNA]
Rimonabant affects the expression of SIPA1L1 mRNA
CTD PMID:19030233 NCBI chr 6:101,839,351...102,118,408
Ensembl chr 6:101,839,404...102,116,950
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SLC2A4 mRNA] CTD PMID:19030233 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc39a10 solute carrier family 39 member 10 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SLC39A10 mRNA] CTD PMID:19030233 NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325
JBrowse link
G Slc39a8 solute carrier family 39 member 8 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SLC39A8 mRNA] CTD PMID:19030233 NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129
JBrowse link
G Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SMARCA2 mRNA] CTD PMID:19030233 NCBI chr 1:224,191,125...224,358,640
Ensembl chr 1:224,191,125...224,358,684
JBrowse link
G Socs1 suppressor of cytokine signaling 1 decreases expression EXP Rimonabant results in decreased expression of SOCS1 mRNA CTD PMID:30365523 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression EXP Rimonabant results in decreased expression of SOCS3 mRNA CTD PMID:30365523 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Sorbs2 sorbin and SH3 domain containing 2 affects expression ISO Rimonabant affects the expression of SORBS2 mRNA CTD PMID:19030233 NCBI chr16:46,435,220...46,748,743
Ensembl chr16:46,435,237...46,626,514
JBrowse link
G Sparc secreted protein acidic and cysteine rich multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SPARC mRNA]
Rimonabant affects the expression of SPARC mRNA
CTD PMID:19030233 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SPTBN1 mRNA]
Rimonabant affects the expression of SPTBN1 mRNA
CTD PMID:19030233 NCBI chr14:103,842,684...104,008,507
Ensembl chr14:103,842,684...104,008,507
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of SRC protein] CTD PMID:16046413 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srp72 signal recognition particle 72 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SRP72 mRNA] CTD PMID:19030233 NCBI chr14:31,168,175...31,195,717 JBrowse link
G St3gal6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ST3GAL6 mRNA] CTD PMID:19030233 NCBI chr11:42,061,282...42,121,801
Ensembl chr11:42,077,621...42,121,776
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of STAT3 protein] CTD PMID:16046413 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stat6 signal transducer and activator of transcription 6 multiple interactions ISO [MIR466J mRNA co-treated with Rimonabant] affects the expression of STAT6 mRNA; Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of STAT6 mRNA] CTD PMID:30910812 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
G Stim2 stromal interaction molecule 2 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of STIM2 mRNA]
Rimonabant affects the expression of STIM2 mRNA
CTD PMID:19030233 NCBI chr14:56,878,428...57,004,405
Ensembl chr14:56,878,645...57,004,179
JBrowse link
G Strn4 striatin 4 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of STRN4 mRNA] CTD PMID:19030233 NCBI chr 1:77,482,267...77,511,862
Ensembl chr 1:77,482,094...77,511,858
JBrowse link
G Tcea1 transcription elongation factor A1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of TCEA1 mRNA] CTD PMID:19030233 NCBI chr 5:14,631,454...14,668,769
Ensembl chr 5:14,631,454...14,668,745
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression EXP Rimonabant results in decreased expression of TGFB1 mRNA CTD PMID:30365523 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgif2 TGFB-induced factor homeobox 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TGIF2 mRNA] CTD PMID:19030233 NCBI chr 3:145,333,152...145,348,599
Ensembl chr 3:145,333,418...145,348,596
JBrowse link
G Th tyrosine hydroxylase multiple interactions
increases activity
EXP Rimonabant affects the reaction [PRKN mutant form affects the activity of TH protein]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of TH protein]
Rimonabant results in increased activity of TH protein
CTD PMID:9188039 PMID:10700552 PMID:15882845 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Thy1 Thy-1 cell surface antigen multiple interactions EXP Rimonabant inhibits the reaction [methanandamide affects the expression of THY1 mRNA] CTD PMID:17591864 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 decreases expression EXP Rimonabant results in decreased expression of TIMP1 mRNA CTD PMID:21863215 PMID:30365523 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tmed7 transmembrane p24 trafficking protein 7 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of TMED7 mRNA] CTD PMID:19030233 NCBI chr18:39,318,564...39,325,640
Ensembl chr18:39,297,351...39,325,640
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO
EXP
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of TNF]; Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of TNF protein]]
Rimonabant results in decreased expression of TNF mRNA
CTD PMID:20110567 PMID:30365523 PMID:30769029 PMID:32832534 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tomm20 translocase of outer mitochondrial membrane 20 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TOMM20 mRNA] CTD PMID:19030233 NCBI chr19:54,925,197...54,935,188
Ensembl chr19:54,923,402...54,935,198
JBrowse link
G Tpm4 tropomyosin 4 affects expression
multiple interactions
ISO Rimonabant affects the expression of TPM4 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of TPM4 mRNA]
CTD PMID:19030233 NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions ISO Rimonabant inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; Rimonabant inhibits the reaction [Capsaicin binds to and results in increased activity of TRPV1 protein]; Rimonabant inhibits the reaction [N-(4-hydroxyphenyl)arachidonylamide binds to and results in increased activity of TRPV1 protein] CTD PMID:11278420 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
G Tsen2 tRNA splicing endonuclease subunit 2 affects expression
multiple interactions
ISO Rimonabant affects the expression of TSEN2 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TSEN2 mRNA]
CTD PMID:19030233 NCBI chr 4:148,602,805...148,638,219
Ensembl chr 4:148,602,863...148,638,215
JBrowse link
G Tspan5 tetraspanin 5 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TSPAN5 mRNA] CTD PMID:19030233 NCBI chr 2:227,294,180...227,469,361
Ensembl chr 2:227,294,217...227,465,664
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression EXP Rimonabant results in increased expression of TXNRD1 mRNA CTD PMID:30365523 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Unc5b unc-5 netrin receptor B multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of UNC5B mRNA] CTD PMID:30910812 NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537
JBrowse link
G Usp46 ubiquitin specific peptidase 46 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of USP46 mRNA] CTD PMID:19030233 NCBI chr14:34,150,055...34,219,227
Ensembl chr14:34,150,004...34,219,227
JBrowse link
G Usp48 ubiquitin specific peptidase 48 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of USP48 mRNA] CTD PMID:19030233 NCBI chr 5:149,800,189...149,867,838
Ensembl chr 5:149,800,179...149,867,719
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions
decreases expression
ISO Rimonabant inhibits the reaction [Glucose results in increased expression of VCAM1 protein]
Rimonabant results in decreased expression of VCAM1 protein
CTD PMID:21373835 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vcl vinculin multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of VCL mRNA] CTD PMID:19030233 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of and results in decreased secretion of VEGFA protein] CTD PMID:15313899 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vim vimentin multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of VIM mRNA]
Rimonabant affects the expression of VIM mRNA
CTD PMID:19030233 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vldlr very low density lipoprotein receptor multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of VLDLR mRNA] CTD PMID:19030233 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
JBrowse link
G Wdr26 WD repeat domain 26 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WDR26 mRNA] CTD PMID:19030233 NCBI chr13:92,930,282...92,972,061
Ensembl chr13:92,930,285...92,977,295
JBrowse link
G Wdr7 WD repeat domain 7 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of WDR7 mRNA] CTD PMID:19030233 NCBI chr18:57,165,482...57,448,568
Ensembl chr18:57,165,488...57,448,540
JBrowse link
G Wsb1 WD repeat and SOCS box-containing 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WSB1 mRNA] CTD PMID:19030233 NCBI chr10:64,202,761...64,219,039
Ensembl chr10:64,202,763...64,219,019
JBrowse link
G Wwp1 WW domain containing E3 ubiquitin protein ligase 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WWP1 mRNA] CTD PMID:19030233 NCBI chr 5:33,092,379...33,185,887
Ensembl chr 5:33,098,494...33,186,046
JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WWTR1 mRNA] CTD PMID:19030233 NCBI chr 2:141,651,159...141,766,919
Ensembl chr 2:141,648,108...141,766,968
JBrowse link
G Xbp1 X-box binding protein 1 increases expression
multiple interactions
ISO Rimonabant results in increased expression of XBP1 mRNA
[Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of XBP1 mRNA alternative form]; gemcitabine promotes the reaction [Rimonabant results in increased expression of XBP1 mRNA]
CTD PMID:21525939 PMID:31054322 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Zdhhc2 zinc finger DHHC-type palmitoyltransferase 2 affects expression
multiple interactions
ISO Rimonabant affects the expression of ZDHHC2 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ZDHHC2 mRNA]
CTD PMID:19030233 NCBI chr16:51,808,465...51,878,060
Ensembl chr16:51,808,468...51,878,060
JBrowse link
G Zdhhc7 zinc finger DHHC-type palmitoyltransferase 7 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of ZDHHC7 mRNA] CTD PMID:19030233 NCBI chr19:48,139,309...48,156,673
Ensembl chr19:48,139,527...48,156,673
JBrowse link
G Zhx1 zinc fingers and homeoboxes 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ZHX1 mRNA] CTD PMID:19030233 NCBI chr 7:89,582,363...89,611,337
Ensembl chr 7:89,582,243...89,611,264
JBrowse link
G Znrf2 zinc and ring finger 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ZNRF2 mRNA] CTD PMID:19030233 NCBI chr 4:83,950,406...84,032,676
Ensembl chr 4:83,949,309...84,027,818
JBrowse link
G Zwilch zwilch kinetochore protein affects expression ISO Rimonabant affects the expression of ZWILCH mRNA CTD PMID:19030233 NCBI chr 8:64,638,401...64,670,911
Ensembl chr 8:64,637,672...64,675,916
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    chemical entity 19821
      atom 19819
        nonmetal atom 19707
          nitrogen atom 18765
            nitrogen molecular entity 18765
              organonitrogen compound 18538
                organonitrogen heterocyclic compound 17643
                  piperidines 7569
                    amidopiperidine 440
                      (2S)-4-(2,5-difluorophenyl)-N-methyl-2-phenyl-N-piperidin-4-yl-2,5-dihydro-1H-pyrrole-1-carboxamide 0
                      1-\{2-[(4-chlorophenyl)amino]-2-oxoethyl\}-N-(1-isopropylpiperidin-4-yl)-1H-indole-2-carboxamide 0
                      1-\{[5-(5-chloro-2-thienyl)isoxazol-3-yl]methyl\}-3-cyano-N-(1-isopropylpiperidin-4-yl)-7-methyl-1H-indole-2-carboxamide 0
                      1-\{[5-(5-chloro-2-thienyl)isoxazol-3-yl]methyl\}-N-(1-isopropylpiperidin-4-yl)-1H-indole-2-carboxamide 0
                      AM-251 150
                      N-(1-isopropylpiperidin-4-yl)-1-(3-methoxybenzyl)-1H-indole-2-carboxamide 0
                      N-[1-(3-methylbutyl)piperidin-4-yl]-N-\{4-[methyl(pyridin-4-yl)amino]benzyl\}-4-pentylbenzamide 0
                      [(1R)-2-(3-\{methyl[1-(naphthalen-2-ylcarbonyl)piperidin-4-yl]carbamoyl\}naphthalen-2-yl)-1-naphthalen-1-yl-2-oxoethyl]phosphonic acid 0
                      rimonabant 323
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic acid 18373
                                        carboacyl group 17485
                                          univalent carboacyl group 17485
                                            carbamoyl group 17299
                                              carboxamide 17299
                                                monocarboxylic acid amide 15008
                                                  amidopiperidine 440
                                                    (2S)-4-(2,5-difluorophenyl)-N-methyl-2-phenyl-N-piperidin-4-yl-2,5-dihydro-1H-pyrrole-1-carboxamide 0
                                                    1-\{2-[(4-chlorophenyl)amino]-2-oxoethyl\}-N-(1-isopropylpiperidin-4-yl)-1H-indole-2-carboxamide 0
                                                    1-\{[5-(5-chloro-2-thienyl)isoxazol-3-yl]methyl\}-3-cyano-N-(1-isopropylpiperidin-4-yl)-7-methyl-1H-indole-2-carboxamide 0
                                                    1-\{[5-(5-chloro-2-thienyl)isoxazol-3-yl]methyl\}-N-(1-isopropylpiperidin-4-yl)-1H-indole-2-carboxamide 0
                                                    AM-251 150
                                                    N-(1-isopropylpiperidin-4-yl)-1-(3-methoxybenzyl)-1H-indole-2-carboxamide 0
                                                    N-[1-(3-methylbutyl)piperidin-4-yl]-N-\{4-[methyl(pyridin-4-yl)amino]benzyl\}-4-pentylbenzamide 0
                                                    [(1R)-2-(3-\{methyl[1-(naphthalen-2-ylcarbonyl)piperidin-4-yl]carbamoyl\}naphthalen-2-yl)-1-naphthalen-1-yl-2-oxoethyl]phosphonic acid 0
                                                    rimonabant 323
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