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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:hydroxypiperidine
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Accession:CHEBI:48590 term browser browse the term
Synonyms:related_synonym: hydroxypiperidines

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alvocidib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase multiple interactions ISO [alvocidib co-treated with Bortezomib co-treated with ABL1 protein] results in decreased phosphorylation of LYN protein; [alvocidib co-treated with Bortezomib co-treated with ABL1] results in decreased phosphorylation of CRKL protein; [alvocidib co-treated with Bortezomib] results in decreased expression of ABL1 protein CTD PMID:15039284 NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases localization ISO alvocidib results in increased localization of AIFM1 protein CTD PMID:12734434 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [alvocidib co-treated with Bortezomib] results in decreased expression of AKT1 protein modified form CTD PMID:15039284 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO [Imatinib Mesylate co-treated with alvocidib] results in decreased expression of BAD protein CTD PMID:12231544 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453 		JBrowse link
G Bag1 BAG cochaperone 1 decreases expression ISO alvocidib results in decreased expression of BAG1 mRNA; alvocidib results in decreased expression of BAG1 protein; alvocidib results in decreased expression of BAG1 protein alternative form CTD PMID:10887097 PMID:15972445 NCBI chr 5:57,254,421...57,267,002
Ensembl chr 5:57,254,421...57,267,002 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects localization
increases cleavage
increases expression
multiple interactions		 ISO alvocidib affects the localization of BAX protein
alvocidib results in increased cleavage of BAX protein
alvocidib results in increased expression of BAX protein
[alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] affects the localization of BAX protein; [alvocidib co-treated with gemcitabine] results in increased expression of BAX protein; [alvocidib co-treated with TNFSF10 protein] results in increased localization of BAX protein; Epothilones promotes the reaction [alvocidib affects the localization of BAX protein]		 CTD PMID:12517783 PMID:12589031 PMID:12734434 PMID:15634644 PMID:15770523 PMID:16951203 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
decreases response to substance
multiple interactions
increases expression		 ISO alvocidib results in decreased expression of BCL2 mRNA; alvocidib results in decreased expression of BCL2 protein
BCL2 protein mutant form results in decreased susceptibility to alvocidib; BCL2 protein results in decreased susceptibility to alvocidib
[alvocidib co-treated with gemcitabine] results in decreased expression of BCL2 protein; BCL2 protein mutant form inhibits the reaction [alvocidib affects the localization of CYCS protein]; BCL2 protein mutant form inhibits the reaction [alvocidib results in increased activity of CASP3 protein]; BCL2 protein mutant form inhibits the reaction [alvocidib results in increased activity of CASP9 protein]; BCL2 protein mutant form inhibits the reaction [alvocidib results in increased cleavage of BID protein]; BCL2 protein mutant form inhibits the reaction [alvocidib results in increased cleavage of PARP1 protein]; BCL2 protein results in decreased susceptibility to [alvocidib co-treated with Epothilones]
alvocidib results in increased expression of BCL2		 CTD PMID:10887097 PMID:10995888 PMID:12170773 PMID:12517783 PMID:12589031 PMID:12734434 PMID:15770523 PMID:15972445 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression		 ISO [alvocidib co-treated with Bortezomib] results in decreased expression of BCL2L1 protein; [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in decreased expression of BCL2L1 protein; Epothilones promotes the reaction [alvocidib results in decreased expression of BCL2L1 mRNA]; Epothilones promotes the reaction [alvocidib results in decreased expression of BCL2L1 protein]
alvocidib results in decreased expression of BCL2L1; alvocidib results in decreased expression of BCL2L1 mRNA; alvocidib results in decreased expression of BCL2L1 protein		 CTD PMID:12517783 PMID:15039284 PMID:15634644 PMID:16820931 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810 		JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
increases cleavage		 ISO [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased cleavage of BID protein; [alvocidib co-treated with TNFSF10 protein] results in decreased expression of BID protein; [Imatinib Mesylate co-treated with alvocidib] results in increased activity of BID protein; BCL2 protein mutant form inhibits the reaction [alvocidib results in increased cleavage of BID protein]; Boc-D-FMK inhibits the reaction [alvocidib results in increased cleavage of BID protein] CTD PMID:11464216 PMID:12170773 PMID:12231544 PMID:15634644 PMID:16951203 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression
multiple interactions		 ISO alvocidib results in decreased expression of BIRC3 mRNA; alvocidib results in decreased expression of BIRC3 protein
Epothilones promotes the reaction [alvocidib results in decreased expression of BIRC3 mRNA]; Epothilones promotes the reaction [alvocidib results in decreased expression of BIRC3 protein]		 CTD PMID:12517783 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression		 ISO [alvocidib co-treated with 7-hydroxystaurosporine] results in decreased expression of BIRC5 protein; [alvocidib co-treated with PBOX-6] results in decreased expression of BIRC5 protein; alvocidib inhibits the reaction [Doxorubicin results in increased expression of and results in increased phosphorylation of BIRC5 protein]; alvocidib results in decreased phosphorylation of and results in decreased expression of BIRC5 protein
alvocidib results in decreased expression of BIRC5; alvocidib results in decreased expression of BIRC5 mRNA; alvocidib results in decreased expression of BIRC5 protein		 CTD PMID:12517783 PMID:12517802 PMID:16012789 PMID:16820931 PMID:20206141 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO alvocidib results in increased expression of BTG2 mRNA CTD PMID:21382384 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982 		JBrowse link
G Casp3 caspase 3 affects cleavage
multiple interactions
increases cleavage
increases activity		 ISO
EXP		 alvocidib affects the cleavage of CASP3 protein
alvocidib inhibits the reaction [Colchicine results in increased activity of CASP3 protein]
alvocidib results in increased cleavage of CASP3 protein
alvocidib results in increased activity of CASP3 protein
[alvocidib co-treated with 7-hydroxystaurosporine] results in increased activity of CASP3 protein; [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased cleavage of CASP3 protein; [alvocidib co-treated with gemcitabine] results in increased cleavage of CASP3 protein; [Imatinib Mesylate co-treated with alvocidib] results in increased activity of CASP3 protein; [irinotecan co-treated with alvocidib] results in increased activity of CASP3 protein; alvocidib affects the cleavage of and results in increased activity of CASP3 protein; alvocidib promotes the reaction [Paclitaxel results in increased activity of CASP3 protein]; alvocidib promotes the reaction [romidepsin results in increased activity of CASP3 protein]; alvocidib results in increased cleavage of and results in increased activity of CASP3 protein; BCL2 protein mutant form inhibits the reaction [alvocidib results in increased activity of CASP3 protein]; Boc-D-FMK inhibits the reaction [alvocidib results in increased cleavage of and results in increased activity of CASP3 protein]		 CTD PMID:9808574 PMID:10430095 PMID:10896673 PMID:11482875 PMID:11751522 PMID:12170773 PMID:12231544 PMID:12517783 PMID:12589031 PMID:12941380 PMID:14555534 PMID:15014036 PMID:15634644 PMID:15770523 PMID:16012789 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases cleavage		 ISO [alvocidib co-treated with 7-hydroxystaurosporine] results in increased cleavage of CASP8 protein; [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased cleavage of CASP8 protein; [alvocidib co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein; [Imatinib Mesylate co-treated with alvocidib] results in increased activity of CASP8 protein
alvocidib results in increased cleavage of CASP8 protein		 CTD PMID:10896673 PMID:12231544 PMID:12589031 PMID:15634644 PMID:16012789 PMID:16951203 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106 		JBrowse link
G Casp9 caspase 9 affects cleavage
increases activity
multiple interactions		 ISO alvocidib affects the cleavage of CASP9 protein
alvocidib results in increased activity of CASP9 protein
[alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased cleavage of CASP9 protein; BCL2 protein mutant form inhibits the reaction [alvocidib results in increased activity of CASP9 protein]		 CTD PMID:10896673 PMID:12170773 PMID:15634644 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778 		JBrowse link
G Cbr3 carbonyl reductase 3 decreases expression ISO alvocidib results in decreased expression of CBR3 mRNA CTD PMID:21382384 NCBI chr11:33,909,417...33,917,674
Ensembl chr11:33,909,439...33,917,674 		JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO alvocidib results in decreased expression of and results in decreased activity of CCNA2 protein CTD PMID:16731754 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214 		JBrowse link
G Ccnb1 cyclin B1 multiple interactions
decreases expression		 ISO [alvocidib co-treated with PBOX-6] results in decreased expression of CCNB1 protein; alvocidib inhibits the reaction [Paclitaxel results in increased expression of CCNB1 protein]; alvocidib results in decreased expression of and results in decreased activity of CCNB1 protein
alvocidib results in decreased expression of CCNB1 protein		 CTD PMID:10430095 PMID:12517783 PMID:15014036 PMID:16731754 PMID:20206141 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
decreases activity		 ISO [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in decreased expression of CCND1 protein
alvocidib results in decreased expression of CCND1 protein
alvocidib results in decreased activity of CCND1 protein		 CTD PMID:9802881 PMID:9829756 PMID:10441105 PMID:12517783 PMID:12589031 PMID:12734434 PMID:15634644 PMID:16905211 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO alvocidib results in decreased expression of CCNE1 protein CTD PMID:15014036 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
decreases expression
decreases activity		 ISO [alvocidib co-treated with PBOX-6] results in decreased activity of CDK1 protein
alvocidib results in decreased expression of CDK1 protein modified form
alvocidib results in decreased activity of CDK1 protein		 CTD PMID:9427698 PMID:9802881 PMID:12517783 PMID:16905211 PMID:20206141 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression
decreases activity
multiple interactions		 ISO alvocidib results in decreased expression of CDK2 protein modified form
alvocidib results in decreased activity of CDK2 protein
alvocidib inhibits the reaction [Paclitaxel results in increased activity of CDK2 protein]		 CTD PMID:9802881 PMID:10430095 PMID:12517783 PMID:16905211 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases activity
decreases expression		 ISO alvocidib results in decreased activity of CDK4 protein
alvocidib results in decreased expression of CDK4 protein		 CTD PMID:12517783 PMID:12734434 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 multiple interactions EXP alvocidib inhibits the reaction [Colchicine results in increased expression of CDK5 protein] CTD PMID:12941380 NCBI chr 4:7,282,945...7,287,427
Ensembl chr 4:7,282,948...7,288,383 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
decreases expression
increases cleavage
increases expression
affects expression		 ISO [alvocidib co-treated with gemcitabine] results in increased expression of CDKN1A protein; alvocidib inhibits the reaction [romidepsin results in increased expression of CDKN1A promoter]; alvocidib inhibits the reaction [romidepsin results in increased expression of CDKN1A protein]; Phorbol 12,13-Dibutyrate inhibits the reaction [alvocidib inhibits the reaction [romidepsin results in increased expression of CDKN1A protein]]
alvocidib results in decreased expression of CDKN1A protein
alvocidib results in increased cleavage of CDKN1A protein
alvocidib results in increased expression of CDKN1A protein
alvocidib affects the expression of CDKN1A protein		 CTD PMID:10537362 PMID:12734434 PMID:15014036 PMID:15180955 PMID:15770523 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases cleavage
increases expression		 ISO alvocidib results in increased cleavage of CDKN1B protein
[alvocidib results in increased expression of TP53 protein] which results in increased expression of CDKN1B protein; alvocidib results in increased expression of CDKN1B protein		 CTD PMID:10537362 PMID:12589031 PMID:15180955 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator affects expression
multiple interactions
decreases expression		 ISO alvocidib affects the expression of CFLAR mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [alvocidib results in decreased expression of CFLAR protein]
alvocidib results in decreased expression of CFLAR; alvocidib results in decreased expression of CFLAR protein		 CTD PMID:16820931 PMID:16951203 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein multiple interactions ISO [alvocidib co-treated with Bortezomib co-treated with ABL1] results in decreased phosphorylation of CRKL protein CTD PMID:15039284 NCBI chr11:87,338,606...87,356,644
Ensembl chr11:87,778,312...87,815,043 		JBrowse link
G Cycs cytochrome c, somatic affects localization
multiple interactions		 ISO alvocidib affects the localization of CYCS protein
[alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] affects the localization of CYCS protein; BCL2 protein mutant form inhibits the reaction [alvocidib affects the localization of CYCS protein]		 CTD PMID:12170773 PMID:12517783 PMID:15634644 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein affects localization
multiple interactions		 ISO alvocidib affects the localization of DIABLO protein
[alvocidib co-treated with Bortezomib] results in increased secretion of DIABLO protein; [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] affects the localization of DIABLO protein; [Imatinib Mesylate co-treated with alvocidib] results in increased secretion of DIABLO protein		 CTD PMID:12231544 PMID:12517783 PMID:15039284 PMID:15634644 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330 		JBrowse link
G E2f1 E2F transcription factor 1 increases expression
increases response to substance
decreases expression		 ISO alvocidib results in increased expression of E2F1 protein
E2F1 results in increased susceptibility to alvocidib
alvocidib results in decreased expression of E2F1 mRNA		 CTD PMID:12533675 PMID:21239698 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721 		JBrowse link
G H2ax H2A.X variant histone affects expression ISO alvocidib affects the expression of H2AX protein CTD PMID:15078984 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981 		JBrowse link
G Hmga1 high mobility group AT-hook 1 decreases expression ISO alvocidib results in decreased expression of HMGA1 mRNA CTD PMID:21239698 NCBI chr20:7,132,501...7,140,155
Ensembl chr20:7,136,007...7,138,980 		JBrowse link
G Htra2 HtrA serine peptidase 2 affects localization ISO alvocidib affects the localization of HTRA2 protein CTD PMID:12517783 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994 		JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to IFIT1 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to ISG15 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to MX1 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [POLR2A protein binds to ISG15 gene]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [POLR2A protein binds to ISG15 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [SUPT5H protein binds to IFIT1 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [SUPT5H protein binds to ISG15 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [SUPT5H protein binds to MX1 promoter]]; alvocidib inhibits the reaction [IFNB1 protein results in increased expression of ISG15 mRNA] CTD PMID:23589332 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier multiple interactions ISO alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to ISG15 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [POLR2A protein binds to ISG15 gene]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [POLR2A protein binds to ISG15 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [SUPT5H protein binds to ISG15 promoter]]; alvocidib inhibits the reaction [IFNB1 protein results in increased expression of ISG15 mRNA] CTD PMID:23589332 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Imatinib Mesylate co-treated with alvocidib] results in increased activity of JUN protein CTD PMID:12231544 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression
decreases phosphorylation		 ISO alvocidib results in decreased expression of KIT mRNA; alvocidib results in decreased expression of KIT promoter
alvocidib results in decreased phosphorylation of KIT protein		 CTD PMID:16740725 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase multiple interactions ISO [alvocidib co-treated with Bortezomib co-treated with ABL1 protein] results in decreased phosphorylation of LYN protein CTD PMID:15039284 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions ISO alvocidib promotes the reaction [Bortezomib results in increased phosphorylation of and results in increased activity of MAP2K4 protein] CTD PMID:15039284 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO alvocidib inhibits the reaction [Bortezomib results in increased expression of MAPK1 protein modified form]; alvocidib results in decreased activity of and results in decreased phosphorylation of MAPK1 protein CTD PMID:15014036 PMID:15039284 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased phosphorylation of and results in increased activity of MAPK14 protein CTD PMID:15634644 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO alvocidib inhibits the reaction [Bortezomib results in increased expression of MAPK3 protein modified form]; alvocidib results in decreased activity of and results in decreased phosphorylation of MAPK3 protein CTD PMID:15014036 PMID:15039284 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased phosphorylation of and results in increased activity of MAPK8 protein; alvocidib promotes the reaction [Bortezomib results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:15039284 PMID:15634644 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member affects expression
decreases response to substance
decreases expression
multiple interactions		 ISO alvocidib affects the expression of MCL1 mRNA; alvocidib affects the expression of MCL1 protein
MCL1 results in decreased susceptibility to alvocidib
alvocidib results in decreased expression of MCL1 mRNA; alvocidib results in decreased expression of MCL1 protein
[alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in decreased expression of MCL1 protein; [Imatinib Mesylate co-treated with alvocidib] results in decreased expression of MCL1 protein; Epothilones promotes the reaction [alvocidib results in decreased expression of MCL1 mRNA]; Epothilones promotes the reaction [alvocidib results in decreased expression of MCL1 protein]		 CTD PMID:10887097 PMID:12231544 PMID:12429644 PMID:12517783 PMID:12533675 PMID:15634644 PMID:15972445 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mdm2 MDM2 proto-oncogene decreases expression ISO alvocidib results in decreased expression of MDM2 mRNA; alvocidib results in decreased expression of MDM2 protein CTD PMID:12589031 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328 		JBrowse link
G Mx2 MX dynamin like GTPase 2 multiple interactions ISO alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to MX1 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [SUPT5H protein binds to MX1 promoter]] CTD PMID:23589332 NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950 		JBrowse link
G Nelfa negative elongation factor complex member A multiple interactions ISO alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to IFIT1 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to ISG15 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to MX1 promoter]] CTD PMID:23589332 NCBI chr14:82,093,837...82,117,913
Ensembl chr14:82,093,837...82,117,906 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression
multiple interactions		 ISO alvocidib results in increased expression of NFKBIA protein modified form
alvocidib promotes the reaction [Bortezomib results in increased expression of NFKBIA protein modified form]; Bortezomib promotes the reaction [alvocidib results in increased expression of NFKBIA protein modified form]		 CTD PMID:15039284 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO alvocidib inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage		 ISO [alvocidib co-treated with 7-hydroxystaurosporine] results in increased cleavage of PARP1 protein; [alvocidib co-treated with Bortezomib] results in increased cleavage of PARP1 protein; [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased cleavage of PARP1 protein; [alvocidib co-treated with gemcitabine] results in increased cleavage of PARP1 protein; alvocidib promotes the reaction [Paclitaxel results in increased cleavage of PARP1 protein]; BCL2 protein mutant form inhibits the reaction [alvocidib results in increased cleavage of PARP1 protein] CTD PMID:10430095 PMID:12170773 PMID:12517783 PMID:15039284 PMID:15634644 PMID:15770523 PMID:15972445 PMID:16012789 PMID:20663931 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Pawr pro-apoptotic WT1 regulator multiple interactions EXP alvocidib inhibits the reaction [Colchicine results in increased expression of PAWR protein] CTD PMID:12941380 NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases activity ISO alvocidib results in decreased activity of PCNA protein CTD PMID:10441105 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570 		JBrowse link
G Perp p53 apoptosis effector related to PMP22 increases expression ISO alvocidib results in increased expression of PERP mRNA CTD PMID:21382384 NCBI chr 1:14,224,392...14,236,838
Ensembl chr 1:14,224,393...14,236,846 		JBrowse link
G Polr2a RNA polymerase II subunit A decreases expression
multiple interactions
decreases phosphorylation		 ISO alvocidib results in decreased expression of POLR2A mRNA
alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [POLR2A protein binds to ISG15 gene]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [POLR2A protein binds to ISG15 promoter]]
Bortezomib promotes the reaction [alvocidib results in decreased phosphorylation of POLR2A protein]		 CTD PMID:15039284 PMID:21239698 PMID:23589332 NCBI chr10:56,339,277...56,364,888
Ensembl chr10:56,339,284...56,365,084 		JBrowse link
G Pygb glycogen phosphorylase B affects binding ISO PYGB protein binds to alvocidib CTD PMID:11368340 NCBI chr 3:146,581,063...146,629,504
Ensembl chr 3:146,582,752...146,634,535 		JBrowse link
G Pygl glycogen phosphorylase L affects binding ISO PYGL protein binds to alvocidib CTD PMID:11368340 NCBI chr 6:92,597,759...92,643,734
Ensembl chr 6:92,597,706...92,643,847 		JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases activity
decreases response to substance
multiple interactions
decreases phosphorylation
decreases expression		 ISO alvocidib results in decreased activity of RB1 protein modified form
RB1 results in decreased susceptibility to alvocidib
[docetaxel co-treated with alvocidib] results in decreased phosphorylation of and results in decreased expression of RB1 protein
alvocidib results in decreased phosphorylation of RB1 protein
alvocidib results in decreased expression of RB1 protein; alvocidib results in decreased expression of RB1 protein modified form		 CTD PMID:9829756 PMID:10441105 PMID:15180955 PMID:15297405 PMID:16905211 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342 		JBrowse link
G Rbl1 RB transcriptional corepressor like 1 decreases expression ISO alvocidib results in decreased expression of RBL1 protein CTD PMID:9829756 NCBI chr 3:153,263,692...153,321,351
Ensembl chr 3:153,263,692...153,321,352 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
decreases expression		 ISO [alvocidib co-treated with Bortezomib] results in decreased phosphorylation of and results in decreased activity of STAT3 protein
alvocidib results in decreased expression of STAT3 mRNA		 CTD PMID:15039284 PMID:21239698 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233 		JBrowse link
G Supt5h SPT5 homolog, DSIF elongation factor subunit multiple interactions ISO alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [SUPT5H protein binds to IFIT1 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [SUPT5H protein binds to ISG15 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [SUPT5H protein binds to MX1 promoter]] CTD PMID:23589332 NCBI chr 1:85,437,780...85,466,854
Ensembl chr 1:85,437,780...85,466,854 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases activity ISO alvocidib analog results in decreased activity of TGFB1 protein CTD PMID:31652400 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO alvocidib inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:21204955 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO alvocidib results in increased expression of TNFRSF10A CTD PMID:16820931 NCBI chr15:51,433,853...51,464,215 JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions
increases response to substance
increases expression		 ISO [alvocidib co-treated with TNFSF10 protein] results in decreased expression of BID protein; [alvocidib co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein; [alvocidib co-treated with TNFSF10 protein] results in increased localization of BAX protein
alvocidib results in increased susceptibility to TNFSF10
alvocidib results in increased expression of TNFSF10		 CTD PMID:16820931 PMID:16951203 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899 		JBrowse link
G Tp53 tumor protein p53 decreases expression
multiple interactions
increases expression		 ISO alvocidib results in decreased expression of TP53 protein
[docetaxel co-treated with alvocidib] results in increased expression of TP53 protein
[alvocidib results in increased expression of TP53 protein] which results in increased expression of CDKN1B protein; alvocidib results in increased expression of TP53 protein		 CTD PMID:9808574 PMID:10537362 PMID:12589031 PMID:15180955 PMID:15297405 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO alvocidib results in decreased expression of VEGFA mRNA CTD PMID:21239698 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression
multiple interactions		 ISO alvocidib results in decreased expression of XIAP mRNA; alvocidib results in decreased expression of XIAP protein
[irinotecan co-treated with alvocidib] results in increased cleavage of XIAP protein; Epothilones promotes the reaction [alvocidib results in decreased expression of XIAP mRNA]; Epothilones promotes the reaction [alvocidib results in decreased expression of XIAP protein]		 CTD PMID:10887097 PMID:11751522 PMID:12517783 PMID:15385934 PMID:15972445 PMID:16951203 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000 		JBrowse link
duvoglustat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO 1-Deoxynojirimycin inhibits the reaction [Dietary Fats results in increased expression of ACACA mRNA] CTD PMID:25445511 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910 		JBrowse link
G App amyloid beta precursor protein decreases response to substance ISO 1-Deoxynojirimycin results in decreased susceptibility to APP protein CTD PMID:19028522 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP 1-Deoxynojirimycin inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]; 1-Deoxynojirimycin inhibits the reaction [Tunicamycin results in increased activity of CASP3 protein] CTD PMID:19028522 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Cd36 CD36 molecule multiple interactions ISO 1-Deoxynojirimycin inhibits the reaction [Dietary Fats results in increased expression of CD36 mRNA] CTD PMID:25445511 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO 1-Deoxynojirimycin inhibits the reaction [Dietary Fats results in increased expression of CEBPA mRNA] CTD PMID:25445511 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions EXP 1-Deoxynojirimycin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; 1-Deoxynojirimycin inhibits the reaction [Tunicamycin results in increased expression of DDIT3 protein] CTD PMID:19028522 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084 		JBrowse link
G Fasn fatty acid synthase multiple interactions ISO 1-Deoxynojirimycin inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA] CTD PMID:25445511 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901 		JBrowse link
G Fbp2 fructose-bisphosphatase 2 multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FBP2 protein] CTD PMID:25446853 NCBI chr17:372,554...389,918
Ensembl chr17:372,551...389,967 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of G6PC protein] CTD PMID:25446853 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213 		JBrowse link
G Gck glucokinase multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK protein] CTD PMID:25446853 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO 1-Deoxynojirimycin inhibits the reaction [Dietary Fats results in increased expression of GPT protein] CTD PMID:25445511 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931 		JBrowse link
G Insr insulin receptor multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of INSR protein] CTD PMID:25446853 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414 		JBrowse link
G Lpl lipoprotein lipase multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of LPL mRNA] CTD PMID:25446853 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496 		JBrowse link
G Pc pyruvate carboxylase multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PCX protein] CTD PMID:25446853 NCBI chr 1:219,759,157...219,859,854
Ensembl chr 1:219,759,183...219,859,848 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PCK1 protein] CTD PMID:25446853 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871 		JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] results in increased expression of PDHA1 mRNA CTD PMID:25446853 NCBI chr  X:37,329,779...37,343,410
Ensembl chr  X:37,329,779...37,343,410 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA] CTD PMID:25446853 NCBI chr 3:58,530,870...58,561,494
Ensembl chr 3:58,530,870...58,558,027 		JBrowse link
G Pfkp phosphofructokinase, platelet multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PFKP protein] CTD PMID:25446853 NCBI chr17:68,510,765...68,574,387
Ensembl chr17:68,511,064...68,559,471 		JBrowse link
G Pklr pyruvate kinase L/R multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PKLR protein] CTD PMID:25446853 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592 		JBrowse link
G Ppargc1b PPARG coactivator 1 beta multiple interactions ISO [1-Deoxynojirimycin co-treated with Dietary Fats] results in increased expression of PPARGC1B mRNA CTD PMID:25445511 NCBI chr18:56,626,725...56,650,524
Ensembl chr18:56,626,712...56,728,968 		JBrowse link
haloperidol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases expression
decreases activity		 ISO Haloperidol inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]
Haloperidol results in decreased expression of ABCB1 mRNA
Haloperidol results in decreased activity of ABCB1 protein		 CTD PMID:15946544 PMID:16810505 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
decreases expression		 ISO Haloperidol inhibits the reaction [ABCC1 protein results in decreased susceptibility to Doxorubicin]
Haloperidol results in decreased expression of ABCC1 mRNA		 CTD PMID:15946544 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Haloperidol inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone] CTD PMID:18834354 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621 		JBrowse link
G Adam1a ADAM metallopeptidase domain 1a decreases expression EXP Haloperidol results in decreased expression of ADAM1A mRNA CTD PMID:16715494 NCBI chr12:40,533,731...40,536,632
Ensembl chr12:40,533,632...40,536,620 		JBrowse link
G Adcy5 adenylate cyclase 5 affects response to substance
multiple interactions		 ISO ADCY5 protein affects the susceptibility to Haloperidol
SCH 23390 inhibits the reaction [ADCY5 protein affects the susceptibility to Haloperidol]		 CTD PMID:12223546 NCBI chr11:68,695,839...68,842,452
Ensembl chr11:68,695,839...68,842,320 		JBrowse link
G Adcyap1r1 ADCYAP receptor type I affects expression ISO Haloperidol affects the expression of ADCYAP1R1 mRNA CTD PMID:27900577 NCBI chr 4:85,662,809...85,711,696
Ensembl chr 4:85,662,892...85,711,696 		JBrowse link
G Adora2a adenosine A2a receptor affects response to substance ISO ADORA2A protein affects the susceptibility to Haloperidol CTD PMID:11172060 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873 		JBrowse link
G Agpat1 1-acylglycerol-3-phosphate O-acyltransferase 1 decreases expression ISO Haloperidol results in decreased expression of AGPAT1 mRNA CTD PMID:14647396 NCBI chr20:4,369,399...4,378,272
Ensembl chr20:4,369,178...4,378,269 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression EXP Haloperidol results in decreased expression of AKT1 mRNA CTD PMID:15860345 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 increases expression EXP Haloperidol results in increased expression of AKT2 mRNA CTD PMID:15860345 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162 		JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP Haloperidol results in increased expression of ALDOA mRNA CTD PMID:15860345 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C increases expression EXP Haloperidol results in increased expression of ALDOC mRNA CTD PMID:15860345 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126 		JBrowse link
G Ap2a2 adaptor related protein complex 2 subunit alpha 2 decreases expression EXP Haloperidol results in decreased expression of AP2A2 mRNA CTD PMID:15860345 NCBI chr 1:214,534,217...214,607,497
Ensembl chr 1:214,534,284...214,606,169 		JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 affects expression EXP Haloperidol affects the expression of AP2B1 mRNA CTD PMID:15860345 NCBI chr10:70,516,462...70,621,973
Ensembl chr10:70,520,206...70,621,977 		JBrowse link
G Apod apolipoprotein D increases expression ISO Haloperidol results in increased expression of APOD mRNA CTD PMID:14647396 NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein increases expression
multiple interactions		 EXP Haloperidol results in increased expression of ARC mRNA
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of ARC mRNA]		 CTD PMID:18208916 PMID:19695244 NCBI chr 7:115,907,097...115,911,059
Ensembl chr 7:115,907,097...115,910,541 		JBrowse link
G Arf1 ADP-ribosylation factor 1 decreases expression EXP Haloperidol results in decreased expression of ARF1 mRNA CTD PMID:15860345 NCBI chr10:45,562,700...45,579,214
Ensembl chr10:45,563,547...45,579,029 		JBrowse link
G Arf3 ADP-ribosylation factor 3 decreases expression EXP Haloperidol results in decreased expression of ARF3 mRNA CTD PMID:15860345 NCBI chr 7:140,412,463...140,438,751
Ensembl chr 7:140,398,199...140,437,467 		JBrowse link
G Arl3 ADP ribosylation factor like GTPase 3 decreases expression EXP Haloperidol results in decreased expression of ARL3 mRNA CTD PMID:15860345 NCBI chr 1:266,287,015...266,333,099
Ensembl chr 1:266,287,017...266,333,105 		JBrowse link
G Arl5a ADP-ribosylation factor like GTPase 5A decreases expression EXP Haloperidol results in decreased expression of ARL5A mRNA CTD PMID:15860345 NCBI chr 3:37,922,544...37,947,434
Ensembl chr 3:37,924,793...37,947,283 		JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 increases expression ISO Haloperidol results in increased expression of ARPC4 mRNA CTD PMID:14647396 NCBI chr 4:145,330,457...145,340,985
Ensembl chr 4:145,330,457...145,340,984 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO Haloperidol results in decreased expression of ASNS mRNA CTD PMID:17175557 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 decreases expression EXP Haloperidol results in decreased expression of ATP1A1 mRNA CTD PMID:15860345 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023 		JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 decreases expression EXP Haloperidol results in decreased expression of ATP1A3 mRNA CTD PMID:15860345 NCBI chr 1:81,852,423...81,881,565
Ensembl chr 1:81,852,429...81,881,549 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 increases expression EXP Haloperidol results in increased expression of ATP1B1 mRNA CTD PMID:15860345 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004 		JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 decreases expression EXP Haloperidol results in decreased expression of ATP1B2 mRNA CTD PMID:15860345 NCBI chr10:56,205,622...56,211,879
Ensembl chr10:56,205,625...56,211,891 		JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 increases expression EXP Haloperidol results in increased expression of ATP1B3 mRNA CTD PMID:15860345 NCBI chr 8:104,190,032...104,221,342
Ensembl chr 8:104,190,032...104,221,342 		JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 decreases expression ISO Haloperidol results in decreased expression of ATP6V1B2 mRNA CTD PMID:16465460 NCBI chr16:22,326,537...22,350,143
Ensembl chr16:22,326,529...22,350,155 		JBrowse link
G Axin2 axin 2 decreases expression EXP Haloperidol results in decreased expression of AXIN2 mRNA CTD PMID:16715494 NCBI chr10:97,212,483...97,238,824
Ensembl chr10:97,212,432...97,239,642 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression		 EXP Haloperidol results in decreased expression of BAX protein
Haloperidol results in increased expression of BAX mRNA; Haloperidol results in increased expression of BAX protein		 CTD PMID:16462815 PMID:17069804 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP Haloperidol results in increased expression of BCL2 protein CTD PMID:17069804 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression
decreases expression		 EXP EPO protein inhibits the reaction [Haloperidol results in decreased expression of BCL2L1 protein]
Haloperidol results in increased expression of BCL2L1 protein		 CTD PMID:16462815 PMID:17805306 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression
decreases expression		 EXP
ISO		 BDNF protein inhibits the reaction [Haloperidol results in increased activity of CASP3 protein]; EPO protein inhibits the reaction [Haloperidol results in decreased expression of BDNF protein]; Haloperidol inhibits the reaction [Rotenone results in decreased expression of BDNF mRNA]
Haloperidol results in increased expression of BDNF mRNA
Haloperidol results in increased expression of BDNF protein
Haloperidol inhibits the reaction [Cocaine results in decreased expression of BDNF protein]
Haloperidol results in decreased expression of BDNF mRNA; Haloperidol results in decreased expression of BDNF protein		 CTD PMID:11488957 PMID:12393228 PMID:12478621 PMID:15168214 PMID:17442543 PMID:17805306 PMID:18208916 PMID:20554863 PMID:29182611 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210 		JBrowse link
G Bet1l Bet1 golgi vesicular membrane trafficking protein-like affects expression EXP Haloperidol affects the expression of BET1L mRNA CTD PMID:15860345 NCBI chr 1:213,602,836...213,606,507
Ensembl chr 1:213,602,850...213,605,643 		JBrowse link
G Bptf bromodomain PHD finger transcription factor decreases expression ISO Haloperidol results in decreased expression of BPTF mRNA CTD PMID:14647396 NCBI chr10:95,248,573...95,350,162
Ensembl chr10:95,250,294...95,349,789 		JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A decreases expression EXP
ISO		 Haloperidol results in decreased expression of CACNA1A mRNA CTD PMID:14647396 PMID:16715494 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550 		JBrowse link
G Calca calcitonin-related polypeptide alpha affects activity EXP Haloperidol affects the activity of CALCA protein CTD PMID:10075105 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911 		JBrowse link
G Calm2 calmodulin 2 increases expression EXP Haloperidol results in increased expression of CALM2 mRNA CTD PMID:19289156 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions
increases expression
decreases expression		 EXP Haloperidol results in decreased expression of and results in decreased phosphorylation of CAMK2A protein
Haloperidol results in increased expression of CAMK2A mRNA
Haloperidol results in decreased expression of CAMK2A protein		 CTD PMID:15860345 PMID:18061412 PMID:19289156 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression EXP Haloperidol results in decreased expression of CAMK2B mRNA CTD PMID:15860345 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta decreases expression EXP Haloperidol results in decreased expression of CAMK2D mRNA CTD PMID:15860345 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039 		JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV decreases expression
increases expression		 EXP Haloperidol results in decreased expression of CAMK4 protein
Haloperidol results in increased expression of CAMK4 mRNA		 CTD PMID:15860345 PMID:19289156 NCBI chr18:25,746,878...25,975,962
Ensembl chr18:25,749,098...25,965,957 		JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1 decreases expression EXP Haloperidol results in decreased expression of CAMKK1 protein CTD PMID:19289156 NCBI chr10:59,585,023...59,608,180
Ensembl chr10:59,585,072...59,608,165 		JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 decreases expression EXP Haloperidol results in decreased expression of CAMKK2 protein CTD PMID:19289156 NCBI chr12:39,253,409...39,302,601
Ensembl chr12:39,253,409...39,302,601 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity		 EXP BDNF protein inhibits the reaction [Haloperidol results in increased activity of CASP3 protein]; EPO protein inhibits the reaction [Haloperidol results in increased expression of CASP3 protein] CTD PMID:15168214 PMID:17805306 PMID:18590723 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Cat catalase multiple interactions
decreases expression
decreases activity		 EXP Carvedilol inhibits the reaction [Haloperidol results in decreased expression of CAT protein]; Haloperidol results in decreased activity of and results in decreased expression of CAT protein; Zolpidem inhibits the reaction [Haloperidol results in decreased activity of CAT] CTD PMID:12010767 PMID:12482469 PMID:16564057 PMID:17513028 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Cck cholecystokinin increases expression EXP Haloperidol results in increased expression of CCK mRNA CTD PMID:10974607 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392 		JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP Haloperidol results in decreased expression of CCND1 mRNA CTD PMID:15860345 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325 		JBrowse link
G Ccnd3 cyclin D3 increases expression EXP Haloperidol results in increased expression of CCND3 mRNA CTD PMID:15860345 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943 		JBrowse link
G Ccnl1 cyclin L1 increases expression EXP Haloperidol results in increased expression of CCNL1 mRNA CTD PMID:15860345 NCBI chr 2:157,747,295...157,759,838
Ensembl chr 2:157,747,542...157,759,838 		JBrowse link
G Cdc42 cell division cycle 42 increases expression EXP Haloperidol results in increased expression of CDC42 mRNA CTD PMID:15860345 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression EXP Haloperidol results in increased expression of CDK4 mRNA CTD PMID:15860345 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 increases expression EXP Haloperidol results in increased expression of CDK5 mRNA CTD PMID:15860345 NCBI chr 4:7,282,945...7,287,427
Ensembl chr 4:7,282,948...7,288,383 		JBrowse link
G Chl1 cell adhesion molecule L1-like decreases expression ISO Haloperidol results in decreased expression of CHL1 mRNA CTD PMID:14647396 NCBI chr 4:70,269,414...70,331,313
Ensembl chr 4:70,252,366...70,330,803 		JBrowse link
G Chn1 chimerin 1 decreases expression ISO Haloperidol results in decreased expression of CHN1 mRNA CTD PMID:14647396 NCBI chr 3:60,512,360...60,668,413
Ensembl chr 3:60,513,077...60,611,924 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 affects response to substance ISO CHRM4 affects the susceptibility to Haloperidol CTD PMID:21269601 NCBI chr 3:80,833,272...80,841,165
Ensembl chr 3:80,833,272...80,841,006 		JBrowse link
G Cldn11 claudin 11 decreases expression ISO Haloperidol results in decreased expression of CLDN11 mRNA CTD PMID:17177202 NCBI chr 2:115,823,541...115,836,846
Ensembl chr 2:115,823,538...115,836,846 		JBrowse link
G Clta clathrin, light chain A affects expression EXP Haloperidol affects the expression of CLTA mRNA CTD PMID:15860345 NCBI chr 5:59,490,689...59,509,139
Ensembl chr 5:59,491,096...59,509,138 		JBrowse link
G Cltb clathrin, light chain B decreases expression EXP Haloperidol results in decreased expression of CLTB mRNA CTD PMID:15860345 NCBI chr17:10,537,348...10,554,999
Ensembl chr17:10,537,365...10,554,989 		JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases expression ISO Haloperidol results in decreased expression of CNP mRNA CTD PMID:17177202 NCBI chr10:88,490,798...88,497,357
Ensembl chr10:88,490,798...88,497,356 		JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions ISO CNR1 protein affects the reaction [[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]]; CNR1 protein affects the reaction [[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]] CTD PMID:28017790 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056 		JBrowse link
G Coil coilin increases expression EXP Haloperidol results in increased expression of COIL mRNA CTD PMID:16715494 NCBI chr10:76,320,676...76,336,169
Ensembl chr10:76,320,041...76,341,418 		JBrowse link
G Cpn1 carboxypeptidase N subunit 1 increases expression EXP Haloperidol results in increased expression of CPN1 mRNA CTD PMID:16715494 NCBI chr 1:263,733,887...263,762,758
Ensembl chr 1:263,733,519...263,762,785 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases activity
increases phosphorylation		 ISO
EXP		 Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of CREB1 protein]
Amphetamine affects the reaction [Haloperidol results in increased activity of CREB1 protein modified form]		 CTD PMID:12125044 PMID:12871586 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435 		JBrowse link
G Crh corticotropin releasing hormone decreases expression ISO Haloperidol results in decreased expression of CRH mRNA CTD PMID:16205782 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863 		JBrowse link
G Crhbp corticotropin releasing hormone binding protein decreases expression EXP Haloperidol results in decreased expression of CRHBP mRNA CTD PMID:16715494 NCBI chr 2:25,141,471...25,153,334
Ensembl chr 2:25,141,471...25,153,334 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression ISO Haloperidol results in decreased expression of CRY1 mRNA CTD PMID:27746588 NCBI chr 7:24,534,593...24,634,098
Ensembl chr 7:24,534,615...24,634,097 		JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 decreases expression EXP Haloperidol results in decreased expression of CSNK2A1 mRNA CTD PMID:16715494 NCBI chr 3:147,713,808...147,760,375
Ensembl chr 3:147,713,821...147,757,862 		JBrowse link
G Cst3 cystatin C increases expression ISO Haloperidol results in increased expression of CST3 mRNA CTD PMID:14647396 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615 		JBrowse link
G Ctnnb1 catenin beta 1 decreases expression
increases expression
multiple interactions		 ISO
EXP		 Haloperidol results in decreased expression of CTNNB1 mRNA
Haloperidol results in increased expression of CTNNB1 protein
DRD2 protein affects the reaction [Haloperidol results in increased expression of CTNNB1 protein]		 CTD PMID:16144542 PMID:18797397 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372 		JBrowse link
G Ctrl chymotrypsin-like increases expression EXP Haloperidol results in increased expression of CTRL mRNA CTD PMID:16715494 NCBI chr19:37,905,864...37,907,714
Ensembl chr19:37,905,864...37,907,714 		JBrowse link
G Ctsk cathepsin K increases expression EXP Haloperidol results in increased expression of CTSK mRNA CTD PMID:16715494 NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects response to substance ISO CYP2D6 protein polymorphism affects the susceptibility to Haloperidol CTD PMID:15538130 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436 		JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 multiple interactions ISO CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol; Fluoxetine inhibits the reaction [CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol]; Fluvoxamine inhibits the reaction [CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol]; nefazodone inhibits the reaction [CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol]; norfluoxetine inhibits the reaction [CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol]; Trazodone inhibits the reaction [CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol] CTD PMID:12584149 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol; Fluoxetine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; Fluvoxamine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; nefazodone inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; norfluoxetine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; Trazodone inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol] CTD PMID:12584149 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399 		JBrowse link
G Dcaf6 DDB1 and CUL4 associated factor 6 decreases expression ISO Haloperidol results in decreased expression of DCAF6 mRNA CTD PMID:14647396 NCBI chr13:83,578,730...83,680,330
Ensembl chr13:83,579,036...83,680,207 		JBrowse link
G Dclk1 doublecortin-like kinase 1 increases expression ISO
EXP		 Haloperidol results in increased expression of DCLK1 mRNA CTD PMID:15860345 PMID:18797397 NCBI chr 2:144,646,255...144,939,389
Ensembl chr 2:144,646,308...144,936,927 		JBrowse link
G Dennd10 DENN domain containing 10 increases expression EXP Haloperidol results in increased expression of DENND10 mRNA CTD PMID:16715494 NCBI chr 1:282,188,080...282,211,588
Ensembl chr 1:282,188,110...282,210,580 		JBrowse link
G Depp1 DEPP1, autophagy regulator increases expression ISO Haloperidol results in increased expression of DEPP1 mRNA CTD PMID:17175557 NCBI chr 4:148,780,330...148,784,566
Ensembl chr 4:148,782,479...148,784,562 		JBrowse link
G Dgka diacylglycerol kinase, alpha decreases expression EXP Haloperidol results in decreased expression of DGKA mRNA CTD PMID:15860345 NCBI chr 7:3,143,826...3,170,764
Ensembl chr 7:3,143,827...3,170,146 		JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase decreases expression EXP Haloperidol results in decreased expression of DLAT mRNA CTD PMID:15860345 NCBI chr 8:55,062,549...55,087,832
Ensembl chr 8:55,062,551...55,087,832 		JBrowse link
G Dpf1 double PHD fingers 1 increases expression ISO Haloperidol results in increased expression of DPF1 mRNA CTD PMID:14647396 NCBI chr 1:87,248,448...87,258,070
Ensembl chr 1:87,248,489...87,258,070 		JBrowse link
G Drd1 dopamine receptor D1 affects binding
increases expression
decreases expression
affects activity		 ISO
EXP		 Haloperidol binds to DRD1 protein
Haloperidol results in increased expression of DRD1 protein
Haloperidol results in decreased expression of DRD1 mRNA
Haloperidol affects the activity of DRD1 protein		 CTD PMID:8750706 PMID:8794996 PMID:12887421 PMID:16983399 PMID:23611293 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541 		JBrowse link
G Drd2 dopamine receptor D2 affects binding
affects activity
multiple interactions
increases expression
affects response to substance		 ISO
EXP		 DRD2 protein binds to Haloperidol; DRD2 protein binds to Haloperidol analog; Haloperidol binds to DRD2 protein
Haloperidol affects the activity of DRD2 protein
[Haloperidol binds to and results in decreased activity of DRD2 protein] which results in increased expression of PPP3CA protein; cyclo(leucylglycine) inhibits the reaction [Haloperidol results in increased expression of DRD2 protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of CTNNB1 protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of DVL3 protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3A protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3B protein]; felbamate inhibits the reaction [Haloperidol affects the activity of DRD2 protein]; Haloperidol binds to and results in decreased activity of DRD2 protein; Haloperidol inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] which results in increased uptake of Dopamine]; Haloperidol inhibits the reaction [iodosulpride binds to DRD2 protein]; Haloperidol inhibits the reaction [Spiperone binds to DRD2 protein]; Haloperidol promotes the reaction [Dopamine binds to DRD2 protein]; zinc chloride inhibits the reaction [Haloperidol binds to DRD2 protein]
Haloperidol results in increased expression of DRD2; Haloperidol results in increased expression of DRD2 mRNA; Haloperidol results in increased expression of DRD2 protein
Haloperidol binds to DRD2; Haloperidol binds to DRD2 protein; Haloperidol binds to DRD2 protein alternative form
[Haloperidol binds to and results in decreased activity of DRD2 protein] which results in decreased susceptibility to Ethanol; [Haloperidol results in increased expression of DRD2 protein] which results in decreased susceptibility to Pentobarbital; Haloperidol binds to and results in decreased activity of DRD2 protein
DRD2 affects the susceptibility to Haloperidol; DRD2 protein affects the susceptibility to Haloperidol
Thioctic Acid inhibits the reaction [Haloperidol results in increased expression of DRD2 mRNA]; Thioctic Acid inhibits the reaction [Haloperidol results in increased expression of DRD2 protein]		 CTD PMID:1351265 PMID:1361536 PMID:1380082 PMID:2945998 PMID:7845605 PMID:7878047 PMID:8115415 PMID:8200438 PMID:8794996 PMID:9109525 PMID:9808703 PMID:10720636 PMID:10936494 PMID:11172060 PMID:11927170 PMID:11997696 PMID:12191584 PMID:12476322 PMID:14552778 PMID:15716360 PMID:16033416 PMID:16144542 PMID:18295747 PMID:19120057 PMID:20361897 PMID:20730801 PMID:23611293 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642 		JBrowse link
G Drd3 dopamine receptor D3 affects binding ISO DRD3 protein binds to Haloperidol analog CTD PMID:14552778 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327 		JBrowse link
G Drd4 dopamine receptor D4 affects activity ISO Haloperidol affects the activity of DRD4 protein CTD PMID:23611293 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483 		JBrowse link
G Drp2 dystrophin related protein 2 increases expression EXP Haloperidol results in increased expression of DRP2 mRNA alternative form CTD PMID:16715494 NCBI chr  X:105,239,623...105,290,233
Ensembl chr  X:105,239,620...105,289,808 		JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 increases response to substance
affects response to substance		 ISO DTNBP1 gene polymorphism results in increased susceptibility to Haloperidol
DTNBP1 protein affects the susceptibility to Haloperidol		 CTD PMID:19369910 NCBI chr17:20,090,136...20,182,332
Ensembl chr17:20,090,246...20,182,206 		JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression EXP Haloperidol results in decreased expression of DUSP1 mRNA CTD PMID:15860345 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418 		JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression EXP Haloperidol results in decreased expression of DUSP6 mRNA CTD PMID:15860345 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392 		JBrowse link
G Dvl3 dishevelled segment polarity protein 3 multiple interactions
increases expression		 EXP DRD2 protein affects the reaction [Haloperidol results in increased expression of DVL3 protein] CTD PMID:16144542 NCBI chr11:84,051,177...84,068,479
Ensembl chr11:84,051,078...84,068,302 		JBrowse link
G Egr1 early growth response 1 affects expression
multiple interactions
increases expression		 EXP
ISO		 Haloperidol affects the expression of EGR1 protein
Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]; OPRM1 protein inhibits the reaction [Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]]
Haloperidol results in increased expression of EGR1 mRNA; Haloperidol results in increased expression of EGR1 protein		 CTD PMID:12243769 PMID:16452686 PMID:17028028 PMID:17913375 PMID:18208916 PMID:19695244 PMID:20184921 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429 		JBrowse link
G Egr2 early growth response 2 affects expression
increases expression
decreases expression		 ISO
EXP		 Haloperidol affects the expression of EGR2 mRNA
Haloperidol results in increased expression of EGR2 mRNA
Haloperidol results in decreased expression of EGR2 protein		 CTD PMID:17028028 PMID:18208916 PMID:19401217 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025 		JBrowse link
G Elk1 ETS transcription factor ELK1 increases phosphorylation
multiple interactions		 ISO
EXP		 Haloperidol results in increased phosphorylation of ELK1 protein
SL 327 inhibits the reaction [Haloperidol results in increased phosphorylation of ELK1 protein]
Nifedipine affects the reaction [Haloperidol results in increased phosphorylation of ELK1 protein]		 CTD PMID:12871586 PMID:17913375 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822 		JBrowse link
G Eno1 enolase 1 increases expression EXP Haloperidol results in increased expression of ENO1 mRNA CTD PMID:15860345 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609 		JBrowse link
G Epo erythropoietin multiple interactions EXP EPO protein inhibits the reaction [Haloperidol results in decreased expression of BCL2L1 protein]; EPO protein inhibits the reaction [Haloperidol results in decreased expression of BDNF protein]; EPO protein inhibits the reaction [Haloperidol results in increased expression of CASP3 protein] CTD PMID:17805306 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions EXP Haloperidol results in increased expression of and results in increased phosphorylation of ERBB2 protein CTD PMID:26961615 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 increases expression
multiple interactions		 EXP Haloperidol results in increased expression of ERBB4 protein
Haloperidol results in increased expression of and results in increased phosphorylation of ERBB4 protein		 CTD PMID:18184445 PMID:26961615 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644 		JBrowse link
G Fabp3 fatty acid binding protein 3 affects response to substance ISO FABP3 affects the susceptibility to Haloperidol CTD PMID:20181611 NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565 		JBrowse link
G Fasn fatty acid synthase increases expression ISO Haloperidol results in increased expression of FASN mRNA CTD PMID:16027736 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901 		JBrowse link
G Fndc4 fibronectin type III domain containing 4 increases expression ISO Haloperidol results in increased expression of FNDC4 mRNA CTD PMID:17175557 NCBI chr 6:26,387,284...26,389,524 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
decreases expression		 ISO
EXP		 8-Hydroxy-2-(di-n-propylamino)tetralin affects the reaction [Haloperidol results in increased expression of FOS protein]; Dizocilpine Maleate inhibits the reaction [Haloperidol results in increased expression of FOS protein]; ifenprodil inhibits the reaction [Haloperidol results in increased expression of FOS protein]; tandospirone inhibits the reaction [Haloperidol results in increased expression of FOS protein]; traxoprodil mesylate inhibits the reaction [Haloperidol results in increased expression of FOS protein]; WAY 100135 inhibits the reaction [tandospirone inhibits the reaction [Haloperidol results in increased expression of FOS protein]]
Haloperidol results in increased expression of FOS mRNA; Haloperidol results in increased expression of FOS protein
Haloperidol results in decreased expression of FOS mRNA; Haloperidol results in decreased expression of FOS protein
8-(3-chlorostyryl)caffeine inhibits the reaction [Haloperidol results in increased expression of FOS mRNA]; 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of FOS mRNA]; Clozapine affects the reaction [Haloperidol results in increased expression of FOS protein]; Dronabinol promotes the reaction [Haloperidol results in increased expression of FOS protein]; Nifedipine affects the reaction [Haloperidol results in increased expression of FOS protein]; Nimodipine affects the reaction [Haloperidol results in increased expression of FOS protein]; Propranolol inhibits the reaction [Haloperidol results in increased expression of FOS protein]; Scopolamine inhibits the reaction [Haloperidol results in increased expression of FOS protein]; Theophylline inhibits the reaction [Haloperidol results in increased expression of FOS mRNA]		 CTD PMID:1393566 PMID:9571656 PMID:9748542 PMID:10199625 PMID:10435392 PMID:11166331 PMID:11409749 PMID:11440804 PMID:11516571 PMID:11602683 PMID:11997696 PMID:12093589 PMID:12125044 PMID:12243769 PMID:12464447 PMID:15120589 PMID:15140647 PMID:17028028 PMID:17913375 PMID:18208916 PMID:18295747 PMID:18521575 PMID:18585397 PMID:18789920 PMID:19352073 PMID:19695244 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 ISO
EXP		 Haloperidol results in increased expression of FOSB protein alternative form
Haloperidol results in increased expression of FOSB modified form; Haloperidol results in increased expression of FOSB mRNA; Haloperidol results in increased expression of FOSB protein
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of FOSB mRNA]		 CTD PMID:8714707 PMID:11180499 PMID:12243769 PMID:15579174 PMID:19695244 PMID:24067299 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions
increases expression		 EXP Amphetamine affects the reaction [Haloperidol results in increased expression of FOSL1 protein]
Haloperidol results in increased expression of FOSL1 mRNA; Haloperidol results in increased expression of FOSL1 protein		 CTD PMID:12125044 PMID:18208916 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression EXP Haloperidol results in increased expression of FOSL2 mRNA CTD PMID:12243769 NCBI chr 6:25,598,936...25,616,995
Ensembl chr 6:25,598,936...25,616,995 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions
increases phosphorylation
affects response to substance		 ISO FYN gene mutant form inhibits the reaction [Haloperidol results in increased phosphorylation of GRIN2B protein]
Haloperidol results in increased phosphorylation of FYN protein
FYN protein affects the susceptibility to Haloperidol		 CTD PMID:16407246 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317 		JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 decreases expression ISO Haloperidol results in decreased expression of GABRA1 mRNA CTD PMID:18797397 NCBI chr10:27,310,718...27,371,802
Ensembl chr10:27,310,725...27,366,665 		JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 increases expression EXP Haloperidol results in increased expression of GABRB3 mRNA CTD PMID:18923069 NCBI chr 1:113,034,251...113,265,364
Ensembl chr 1:112,976,770...113,265,364 		JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions
increases expression
decreases expression		 EXP [Haloperidol co-treated with Fluvoxamine] affects the expression of GAD1 protein
Haloperidol results in increased expression of GAD1 mRNA
Haloperidol results in decreased expression of GAD1 mRNA; Haloperidol results in decreased expression of GAD1 protein		 CTD PMID:12887421 PMID:14519413 PMID:15061247 PMID:15967061 PMID:18923069 PMID:19359144 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157 		JBrowse link
G Gad2 glutamate decarboxylase 2 decreases expression
increases expression		 EXP Haloperidol results in decreased expression of GAD2 mRNA; Haloperidol results in decreased expression of GAD2 protein
Haloperidol results in increased expression of GAD2 mRNA		 CTD PMID:18923069 PMID:19359144 NCBI chr17:89,171,576...89,234,770
Ensembl chr17:89,171,250...89,238,040 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression EXP Haloperidol results in increased expression of GAPDH mRNA CTD PMID:15860345 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962 		JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO Haloperidol results in increased expression of GDPD3 mRNA CTD PMID:17175557 NCBI chr 1:198,199,032...198,209,178
Ensembl chr 1:198,199,622...198,209,150 		JBrowse link
G Gimap5 GTPase, IMAP family member 5 decreases expression EXP Haloperidol results in decreased expression of GIMAP5 mRNA CTD PMID:16715494 NCBI chr 4:78,377,228...78,386,683
Ensembl chr 4:78,378,144...78,385,577 		JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP Haloperidol results in decreased expression of GJA1 protein CTD PMID:18585900 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089 		JBrowse link
G Glul glutamate-ammonia ligase decreases expression EXP Haloperidol results in decreased expression of GLUL mRNA CTD PMID:15860345 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229 		JBrowse link
G Gna12 G protein subunit alpha 12 decreases expression EXP Haloperidol results in decreased expression of GNA12 mRNA CTD PMID:15860345 NCBI chr12:15,890,202...15,971,212
Ensembl chr12:15,890,170...15,971,212 		JBrowse link
G Gnai1 G protein subunit alpha i1 decreases expression EXP Haloperidol results in decreased expression of GNAI1 mRNA CTD PMID:15860345 NCBI chr 4:13,405,136...13,486,866
Ensembl chr 4:13,405,136...13,485,883 		JBrowse link
G Gnai2 G protein subunit alpha i2 decreases expression EXP Haloperidol results in decreased expression of GNAI2 mRNA CTD PMID:15860345 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307 		JBrowse link
G Gnai3 G protein subunit alpha i3 decreases expression EXP Haloperidol results in decreased expression of GNAI3 mRNA CTD PMID:15860345 NCBI chr 2:210,896,779...210,934,733
Ensembl chr 2:210,896,656...210,934,749 		JBrowse link
G Gnas GNAS complex locus decreases expression EXP Haloperidol results in decreased expression of GNAS mRNA CTD PMID:15860345 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483 		JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions EXP Haloperidol inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein] CTD PMID:18603625 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 affects expression EXP Haloperidol affects the expression of GOT2 mRNA CTD PMID:15860345 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO Haloperidol results in increased expression of GPX1 mRNA CTD PMID:14647396 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 decreases expression EXP Haloperidol results in decreased expression of GRIA1 mRNA CTD PMID:15860345 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 increases expression EXP Haloperidol results in increased expression of GRIK2 mRNA CTD PMID:18923069 NCBI chr20:53,791,428...54,517,691
Ensembl chr20:53,789,760...54,517,709 		JBrowse link
G Grik4 glutamate ionotropic receptor kainate type subunit 4 increases expression EXP Haloperidol results in increased expression of GRIK4 mRNA CTD PMID:15860345 NCBI chr 8:46,804,134...47,237,546
Ensembl chr 8:46,806,147...47,094,352 		JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 increases expression ISO
EXP		 Haloperidol results in increased expression of GRIK5 mRNA CTD PMID:14647396 PMID:15860345 NCBI chr 1:81,885,516...81,946,731
Ensembl chr 1:81,885,521...81,946,714 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression
increases expression		 EXP Haloperidol results in decreased expression of GRIN1 mRNA
Haloperidol results in increased expression of GRIN1 mRNA		 CTD PMID:12020038 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A decreases expression EXP Haloperidol results in decreased expression of GRIN2A mRNA; Haloperidol results in decreased expression of GRIN2A protein CTD PMID:12608697 PMID:15860345 PMID:18061412 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions
increases phosphorylation		 ISO FYN gene mutant form inhibits the reaction [Haloperidol results in increased phosphorylation of GRIN2B protein] CTD PMID:16407246 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873 		JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C increases expression EXP Haloperidol results in increased expression of GRIN2C mRNA CTD PMID:15860345 NCBI chr10:103,798,290...103,816,923
Ensembl chr10:103,798,291...103,816,287 		JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D decreases expression EXP Haloperidol results in decreased expression of GRIN2D mRNA CTD PMID:18923069 NCBI chr 1:101,819,068...101,859,146
Ensembl chr 1:101,820,461...101,856,881 		JBrowse link
G Grin3b glutamate ionotropic receptor NMDA type subunit 3B increases expression EXP Haloperidol results in increased expression of GRIN3B mRNA CTD PMID:15860345 NCBI chr 7:12,764,993...12,771,310
Ensembl chr 7:12,764,993...12,771,310 		JBrowse link
G Grk6 G protein-coupled receptor kinase 6 decreases expression EXP Haloperidol results in decreased expression of GRK6 mRNA CTD PMID:16715494 NCBI chr17:9,705,917...9,721,921
Ensembl chr17:9,703,453...9,721,574 		JBrowse link
G Grm1 glutamate metabotropic receptor 1 increases expression EXP Haloperidol results in increased expression of GRM1 mRNA CTD PMID:15860345 NCBI chr 1:4,753,141...5,165,859
Ensembl chr 1:4,753,144...5,165,859 		JBrowse link
G Grm2 glutamate metabotropic receptor 2 increases expression EXP Haloperidol results in increased expression of GRM2 mRNA CTD PMID:18923069 NCBI chr 8:115,344,999...115,358,628
Ensembl chr 8:115,344,999...115,358,046 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha increases expression
multiple interactions		 EXP Haloperidol results in increased expression of GSK3A protein
DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3A protein]		 CTD PMID:16144542 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases expression		 EXP DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3B protein]
Haloperidol results in increased expression of GSK3B mRNA; Haloperidol results in increased expression of GSK3B protein		 CTD PMID:16144542 PMID:19359144 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP Haloperidol results in increased expression of GSTM1 mRNA CTD PMID:15860345 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression EXP Haloperidol results in decreased expression of GSTM2 mRNA CTD PMID:15860345 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
decreases expression		 ISO Haloperidol inhibits the reaction [GSTP1 protein results in decreased susceptibility to Doxorubicin]
Haloperidol results in decreased expression of GSTP1 mRNA		 CTD PMID:15946544 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147 		JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A increases expression ISO Haloperidol results in increased expression of HIGD1A mRNA CTD PMID:14647396 NCBI chr 8:130,482,492...130,491,888
Ensembl chr 8:130,482,493...130,491,998 		JBrowse link
G Hist2h2aa2 histone cluster 2 H2A family member A2 increases expression ISO Haloperidol results in increased expression of H2AC18 mRNA CTD PMID:14647396 NCBI chr 2:198,381,678...198,382,247
Ensembl chr 2:198,388,809...198,389,201
Ensembl chr 2:198,388,809...198,389,201 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases activity
increases expression
multiple interactions		 ISO Haloperidol results in increased activity of HMGCR protein
Haloperidol results in increased expression of HMGCR mRNA
[Haloperidol results in increased activity of HMGCR protein] which results in increased abundance of Cholesterol; [Haloperidol results in increased activity of HMGCR protein] which results in increased abundance of Triglycerides		 CTD PMID:16027736 PMID:17052361 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Haloperidol results in increased expression of HMGCS1 mRNA CTD PMID:16027736 PMID:17052361 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055 		JBrowse link
G Homer1 homer scaffold protein 1 multiple interactions
increases expression		 EXP Cycloserine inhibits the reaction [Haloperidol results in increased expression of HOMER1 mRNA] CTD PMID:12464447 PMID:15860345 PMID:20147574 NCBI chr 2:22,909,550...23,012,303
Ensembl chr 2:22,909,569...23,009,678 		JBrowse link
G Hpcal4 hippocalcin-like 4 decreases expression EXP Haloperidol results in decreased expression of HPCAL4 mRNA CTD PMID:12437575 NCBI chr 5:140,870,127...140,882,242
Ensembl chr 5:140,870,140...140,882,244 		JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 decreases expression
multiple interactions		 ISO Haloperidol results in decreased expression of HSPG2 mRNA
HSPG2 gene results in increased susceptibility to [Haloperidol co-treated with Reserpine]		 CTD PMID:20072119 NCBI chr 5:155,812,096...155,913,751 JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D decreases expression EXP Haloperidol results in decreased expression of HTR1D mRNA CTD PMID:16715494 NCBI chr 5:154,780,958...154,801,505
Ensembl chr 5:154,800,226...154,801,350 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A affects binding
multiple interactions		 EXP
ISO		 Haloperidol binds to HTR2A protein
[Phencyclidine co-treated with Haloperidol] affects the activity of HTR2A protein		 CTD PMID:7520908 PMID:12191584 PMID:15380371 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C decreases expression EXP Haloperidol results in decreased expression of HTR2C mRNA CTD PMID:17868938 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039 		JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression
increases expression		 EXP Haloperidol results in decreased expression of ID2 mRNA
Haloperidol results in increased expression of ID2 mRNA		 CTD PMID:12437575 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915 		JBrowse link
G Ilkap ILK associated serine/threonine phosphatase decreases expression EXP Haloperidol results in decreased expression of ILKAP mRNA CTD PMID:15860345 NCBI chr 9:98,514,599...98,536,586
Ensembl chr 9:98,514,584...98,536,581 		JBrowse link
G Inha inhibin subunit alpha decreases expression EXP Haloperidol results in decreased expression of INHA mRNA CTD PMID:16715494 NCBI chr 9:82,700,482...82,703,383
Ensembl chr 9:82,700,468...82,703,400 		JBrowse link
G Inhbe inhibin subunit beta E increases expression ISO Haloperidol results in increased expression of INHBE mRNA CTD PMID:17175557 NCBI chr 7:70,641,423...70,642,848
Ensembl chr 7:70,640,075...70,643,169 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
decreases expression		 EXP Haloperidol results in increased expression of JUN mRNA; Haloperidol results in increased expression of JUN protein
Haloperidol results in decreased expression of JUN mRNA		 CTD PMID:12093589 PMID:12125044 PMID:15860345 PMID:18208916 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
decreases expression		 EXP 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of JUNB mRNA]
Haloperidol results in decreased expression of JUNB mRNA		 CTD PMID:12093589 PMID:19695244 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756 		JBrowse link
G Kcna1 potassium voltage-gated channel subfamily A member 1 increases expression ISO Haloperidol results in increased expression of KCNA1 mRNA; Haloperidol results in increased expression of KCNA1 protein CTD PMID:18797397 NCBI chr 4:159,190,781...159,192,526
Ensembl chr 4:159,190,804...159,192,526 		JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A member regulatory beta subunit 1 decreases expression ISO Haloperidol results in decreased expression of KCNAB1 mRNA CTD PMID:18797397 NCBI chr 2:155,555,798...156,011,438
Ensembl chr 2:155,718,359...156,009,526 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity		 ISO Haloperidol inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Haloperidol results in decreased activity of KCNH2 protein		 CTD PMID:15671647 PMID:16278312 PMID:16494862 PMID:19583963 PMID:21158687 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253 		JBrowse link
G Kcnip3 potassium voltage-gated channel interacting protein 3 decreases expression ISO Haloperidol results in decreased expression of KCNIP3 mRNA; Haloperidol results in decreased expression of KCNIP3 protein CTD PMID:18797397 NCBI chr 3:120,023,062...120,087,650
Ensembl chr 3:120,023,917...120,087,136 		JBrowse link
G Klc1 kinesin light chain 1 decreases expression ISO Haloperidol results in decreased expression of KLC1 mRNA CTD PMID:18797397 NCBI chr 6:136,330,151...136,373,716
Ensembl chr 6:136,330,383...136,373,721 		JBrowse link
G Kmt2a lysine methyltransferase 2A decreases expression ISO Haloperidol results in decreased expression of KMT2A mRNA CTD PMID:14647396 NCBI chr 8:49,110,407...49,185,872
Ensembl chr 8:49,114,990...49,158,971 		JBrowse link
G Kras KRAS proto-oncogene, GTPase increases expression EXP Haloperidol results in increased expression of KRAS mRNA CTD PMID:15860345 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558 		JBrowse link
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 increases expression ISO Haloperidol results in increased expression of LAMTOR3 mRNA CTD PMID:14647396 NCBI chr 2:243,160,821...243,173,057
Ensembl chr 2:243,160,917...243,173,048 		JBrowse link
G Ldhb lactate dehydrogenase B decreases expression
increases expression		 ISO
EXP		 Haloperidol results in decreased expression of LDHB mRNA
Haloperidol results in increased expression of LDHB mRNA		 CTD PMID:15860345 PMID:16465460 NCBI chr 4:176,701,980...176,719,999
Ensembl chr 4:176,701,983...176,720,012 		JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Haloperidol results in increased expression of LDLR mRNA CTD PMID:17052361 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903 		JBrowse link
G LOC103690091 proSAAS increases expression ISO Haloperidol results in increased expression of PCSK1N mRNA CTD PMID:14647396 NCBI chr  X:15,324,261...15,328,617 JBrowse link
G LOC299277 similar to serine (or cysteine) peptidase inhibitor, clade A, member 3B increases expression ISO Haloperidol results in increased expression of SERPINA3 mRNA CTD PMID:17175557 NCBI chr 6:127,871,895...127,888,287
Ensembl chr 6:127,872,666...127,886,540 		JBrowse link
G Mag myelin-associated glycoprotein decreases expression ISO Haloperidol results in decreased expression of MAG mRNA CTD PMID:17177202 NCBI chr 1:89,345,325...89,360,905
Ensembl chr 1:89,345,429...89,360,733 		JBrowse link
G Map1a microtubule-associated protein 1A increases expression EXP Haloperidol results in increased expression of MAP1A mRNA CTD PMID:15860345 NCBI chr 3:113,251,918...113,272,193
Ensembl chr 3:113,251,778...113,272,186 		JBrowse link
G Map2 microtubule-associated protein 2 increases expression EXP Haloperidol results in increased expression of MAP2 mRNA CTD PMID:15079866 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 decreases expression EXP Haloperidol results in decreased expression of MAP2K1 mRNA CTD PMID:15860345 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 decreases expression
increases expression		 EXP
ISO		 Haloperidol results in decreased expression of MAP2K2 mRNA
Haloperidol results in increased expression of MAP2K2 mRNA		 CTD PMID:14647396 PMID:15860345 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489 		JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 decreases expression EXP Haloperidol results in decreased expression of MAP2K5 mRNA CTD PMID:15860345 NCBI chr 8:68,055,976...68,282,656
Ensembl chr 8:68,055,972...68,282,590 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression EXP Haloperidol results in increased expression of MAP3K1 mRNA CTD PMID:15860345 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207 		JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 increases expression EXP Haloperidol results in increased expression of MAP3K12 mRNA CTD PMID:15860345 NCBI chr 7:144,102,275...144,120,306
Ensembl chr 7:144,102,680...144,109,116 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
decreases expression
multiple interactions		 ISO
EXP		 Haloperidol results in increased phosphorylation of MAPK1 protein
Haloperidol results in decreased expression of MAPK1 mRNA
[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]; Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]; CNR1 protein affects the reaction [[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]]; SL 327 inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]		 CTD PMID:12871586 PMID:15860345 PMID:28017790 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 affects expression EXP Haloperidol affects the expression of MAPK14 mRNA CTD PMID:15860345 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions		 ISO Haloperidol results in increased phosphorylation of MAPK3 protein
[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]; Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]; CNR1 protein affects the reaction [[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]]; SL 327 inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]		 CTD PMID:12871586 PMID:28017790 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Mapk6 mitogen-activated protein kinase 6 affects expression EXP Haloperidol affects the expression of MAPK6 mRNA CTD PMID:15860345 NCBI chr 8:82,328,013...82,351,108
Ensembl chr 8:82,328,020...82,351,108 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation EXP Haloperidol results in increased phosphorylation of MAPK8 protein CTD PMID:17092607 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 affects expression EXP Haloperidol affects the expression of MAPK9 mRNA CTD PMID:15860345 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355 		JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor decreases expression EXP Haloperidol results in decreased expression of MAS1 mRNA CTD PMID:16715494 NCBI chr 1:48,076,761...48,108,218
Ensembl chr 1:48,077,033...48,108,216 		JBrowse link
G Mbp myelin basic protein decreases expression ISO Haloperidol results in decreased expression of MBP mRNA CTD PMID:17177202 NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310 		JBrowse link
G Mchr1 melanin-concentrating hormone receptor 1 affects binding ISO Haloperidol binds to MCHR1 protein CTD PMID:16983399 NCBI chr 7:122,456,846...122,459,324
Ensembl chr 7:122,456,799...122,459,960 		JBrowse link
G Mog myelin oligodendrocyte glycoprotein decreases expression ISO Haloperidol results in decreased expression of MOG mRNA CTD PMID:17177202 NCBI chr20:2,003,871...2,014,284
Ensembl chr20:2,004,052...2,014,286 		JBrowse link
G Ncan neurocan decreases expression ISO Haloperidol results in decreased expression of NCAN mRNA CTD PMID:18797397 NCBI chr16:21,050,243...21,076,707
Ensembl chr16:21,050,243...21,076,707 		JBrowse link
G Ncl nucleolin increases expression ISO Haloperidol results in increased expression of NCL mRNA CTD PMID:14647396 NCBI chr 9:93,369,119...93,377,643
Ensembl chr 9:93,368,932...93,377,643 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase decreases expression ISO Haloperidol results in decreased expression of NEDD4 mRNA CTD PMID:18797397 NCBI chr 8:79,323,408...79,408,842
Ensembl chr 8:79,323,408...79,408,833 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression EXP Haloperidol results in decreased expression of NFKB1 protein CTD PMID:16500086 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689 		JBrowse link
G Ngfr nerve growth factor receptor decreases expression EXP Haloperidol results in decreased expression of NGFR mRNA CTD PMID:16513140 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor increases expression ISO Haloperidol results in increased expression of NOP53 mRNA CTD PMID:14647396 NCBI chr 1:77,836,522...77,843,991
Ensembl chr 1:77,836,196...77,844,189 		JBrowse link
G Nppa natriuretic peptide A affects activity EXP Haloperidol affects the activity of NPPA protein modified form CTD PMID:1363893 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705 		JBrowse link
G Nptx2 neuronal pentraxin 2 decreases expression EXP Haloperidol results in decreased expression of NPTX2 mRNA CTD PMID:18208916 NCBI chr12:12,014,638...12,025,547
Ensembl chr12:12,013,911...12,025,549 		JBrowse link
G Npy neuropeptide Y multiple interactions
increases expression
decreases expression		 EXP Haloperidol promotes the reaction [Amphetamine results in decreased expression of NPY protein]
Haloperidol results in increased expression of NPY protein
Haloperidol results in decreased expression of NPY mRNA		 CTD PMID:7644023 PMID:15985714 PMID:16516965 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO Haloperidol results in increased expression of NR0B2 mRNA CTD PMID:17175557 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression EXP Haloperidol results in increased expression of NR1D1 mRNA CTD PMID:11564422 NCBI chr10:86,683,875...86,690,815
Ensembl chr10:86,683,875...86,690,815 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 affects response to substance
multiple interactions
increases expression
decreases expression		 ISO
EXP		 NR4A1 affects the susceptibility to Haloperidol
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of NR4A1 mRNA]
Haloperidol results in decreased expression of NR4A1 mRNA		 CTD PMID:10987852 PMID:11564422 PMID:14603264 PMID:19695244 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression EXP Haloperidol results in increased expression of NR4A3 mRNA CTD PMID:19695244 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637 		JBrowse link
G Nrg1 neuregulin 1 increases expression EXP Haloperidol results in increased expression of NRG1 protein CTD PMID:18184445 PMID:26961615 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434 		JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase decreases expression EXP Haloperidol results in decreased expression of NSF mRNA CTD PMID:15860345 NCBI chr10:91,879,608...91,986,242
Ensembl chr10:91,878,633...92,008,082 		JBrowse link
G Nts neurotensin multiple interactions
increases expression		 ISO
EXP		 SLC6A3 protein promotes the reaction [Haloperidol results in increased expression of NTS mRNA]
Haloperidol results in increased expression of NTS mRNA; Haloperidol results in increased expression of NTS protein
8-(3-chlorostyryl)caffeine inhibits the reaction [Haloperidol results in increased expression of NTS mRNA]; Theophylline inhibits the reaction [Haloperidol results in increased expression of NTS mRNA]		 CTD PMID:10199625 PMID:11120399 PMID:11602683 PMID:12887421 PMID:14603264 PMID:14698760 NCBI chr 7:44,111,594...44,120,998
Ensembl chr 7:44,111,151...44,121,130 		JBrowse link
G Numbl NUMB-like, endocytic adaptor protein decreases expression ISO Haloperidol results in decreased expression of NUMBL mRNA CTD PMID:18797397 NCBI chr 1:84,067,841...84,091,659
Ensembl chr 1:84,067,938...84,091,671 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Haloperidol results in increased expression of NUPR1 mRNA CTD PMID:17175557 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524 		JBrowse link
G Oprl1 opioid related nociceptin receptor 1 affects response to substance ISO OPRL1 affects the susceptibility to Haloperidol CTD PMID:16237164 NCBI chr 3:177,223,779...177,231,663
Ensembl chr 3:177,225,737...177,231,663 		JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions ISO OPRM1 protein inhibits the reaction [Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]] CTD PMID:20184921 NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948 		JBrowse link
G Osbpl8 oxysterol binding protein-like 8 increases expression ISO Haloperidol results in increased expression of OSBPL8 mRNA CTD PMID:14647396 NCBI chr 7:53,878,906...54,030,110
Ensembl chr 7:53,878,610...54,027,892 		JBrowse link
G Park7 Parkinsonism associated deglycase increases expression ISO Haloperidol results in increased expression of PARK7 mRNA CTD PMID:14647396 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724 		JBrowse link
G Pde10a phosphodiesterase 10A increases expression EXP Haloperidol results in increased expression of PDE10A mRNA; Haloperidol results in increased expression of PDE10A protein CTD PMID:18222493 NCBI chr 1:52,360,296...52,544,448
Ensembl chr 1:52,360,296...52,544,450 		JBrowse link
G Pde1b phosphodiesterase 1B increases expression EXP
ISO		 Haloperidol results in increased expression of PDE1B mRNA; Haloperidol results in increased expression of PDE1B protein CTD PMID:14647396 PMID:18222493 NCBI chr 7:145,117,951...145,147,711
Ensembl chr 7:145,117,951...145,145,376 		JBrowse link
G Pde4a phosphodiesterase 4A decreases expression EXP Haloperidol results in decreased expression of PDE4A protein CTD PMID:20222156 NCBI chr 8:22,189,533...22,234,036
Ensembl chr 8:22,189,600...22,233,748 		JBrowse link
G Penk proenkephalin multiple interactions
increases expression		 ISO
EXP		 3,4-dicarboxyphenylglycine promotes the reaction [Haloperidol results in increased expression of PENK mRNA]; Docosahexaenoic Acids inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; Tretinoin inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]
Haloperidol results in increased expression of PENK mRNA; Haloperidol results in increased expression of PENK protein
1-aminocyclopentane-1,2,4-tricarboxylic acid inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; 1-aminoindan-1,5-dicarboxylic acid inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; 2-(2,3-dicarboxycyclopropyl)glycine promotes the reaction [Haloperidol results in increased expression of PENK mRNA]; 5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; Memantine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; Scopolamine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]		 CTD PMID:3838946 PMID:7637876 PMID:12373537 PMID:12727308 PMID:12834887 PMID:12887421 PMID:14603264 PMID:14642644 PMID:15215559 PMID:17224239 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837 		JBrowse link
G Per1 period circadian regulator 1 increases expression ISO Haloperidol results in increased expression of PER1 mRNA CTD PMID:27746588 NCBI chr10:55,681,761...55,696,557
Ensembl chr10:55,687,050...55,695,994 		JBrowse link
G Pfdn5 prefoldin subunit 5 increases expression ISO Haloperidol results in increased expression of PFDN5 mRNA CTD PMID:14647396 NCBI chr 7:143,924,662...143,929,400
Ensembl chr 7:143,924,662...143,929,397 		JBrowse link
G Pfkp phosphofructokinase, platelet increases expression EXP Haloperidol results in increased expression of PFKP mRNA CTD PMID:15860345 NCBI chr17:68,510,765...68,574,387
Ensembl chr17:68,511,064...68,559,471 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 increases expression EXP Haloperidol results in increased expression of PGK1 mRNA CTD PMID:15860345 NCBI chr  X:77,263,399...77,279,373
Ensembl chr  X:77,263,359...77,279,367 		JBrowse link
G Phactr1 phosphatase and actin regulator 1 increases expression ISO Haloperidol results in increased expression of PHACTR1 mRNA CTD PMID:14647396 NCBI chr17:23,245,423...23,761,207 JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein decreases expression EXP Haloperidol results in decreased expression of PICALM mRNA CTD PMID:15860345 NCBI chr 1:154,377,229...154,458,966
Ensembl chr 1:154,377,247...154,458,425 		JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 decreases expression EXP Haloperidol results in decreased expression of PIK3R3 mRNA CTD PMID:16715494 NCBI chr 5:135,069,972...135,145,633
Ensembl chr 5:135,074,297...135,142,488 		JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta decreases expression EXP Haloperidol results in decreased expression of PKIB mRNA CTD PMID:15860345 NCBI chr20:40,616,868...40,712,598
Ensembl chr20:40,618,128...40,712,592 		JBrowse link
G Pkm pyruvate kinase M1/2 increases expression EXP Haloperidol results in increased expression of PKM mRNA CTD PMID:15860345 NCBI chr 8:64,480,963...64,502,957
Ensembl chr 8:64,481,172...64,502,722 		JBrowse link
G Plp1 proteolipid protein 1 decreases expression ISO Haloperidol results in decreased expression of PLP1 mRNA CTD PMID:17177202 PMID:18797397 NCBI chr  X:107,494,326...107,511,355
Ensembl chr  X:107,496,072...107,511,348 		JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A decreases expression EXP Haloperidol results in decreased expression of PPM1A mRNA CTD PMID:15860345 NCBI chr 6:94,433,658...94,484,979
Ensembl chr 6:94,429,068...94,484,351 		JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B decreases expression EXP Haloperidol results in decreased expression of PPM1B mRNA CTD PMID:15860345 NCBI chr 6:8,219,385...8,280,127
Ensembl chr 6:8,218,696...8,280,124 		JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta decreases expression EXP Haloperidol results in decreased expression of PPP1CB mRNA CTD PMID:15860345 NCBI chr 6:23,548,507...23,581,136
Ensembl chr 6:23,549,317...23,581,052 		JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma decreases expression EXP Haloperidol results in decreased expression of PPP1CC mRNA CTD PMID:15860345 NCBI chr12:39,864,302...39,882,030
Ensembl chr12:39,864,295...39,882,030 		JBrowse link
G Ppp1r1a protein phosphatase 1, regulatory (inhibitor) subunit 1A decreases expression EXP Haloperidol results in decreased expression of PPP1R1A mRNA CTD PMID:15860345 NCBI chr 7:145,146,480...145,154,131
Ensembl chr 7:145,146,481...145,154,131 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B increases phosphorylation ISO Haloperidol results in increased phosphorylation of PPP1R1B protein CTD PMID:12871586 NCBI chr10:86,303,727...86,312,770
Ensembl chr10:86,303,727...86,312,762 		JBrowse link
G Ppp1r2 protein phosphatase 1, regulatory (inhibitor) subunit 2 decreases expression EXP Haloperidol results in decreased expression of PPP1R2 mRNA CTD PMID:15860345 NCBI chr11:72,748,789...73,034,683
Ensembl chr11:73,022,063...73,034,682 		JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B decreases expression EXP Haloperidol results in decreased expression of PPP1R9B protein CTD PMID:16844384 NCBI chr10:82,800,704...82,816,735
Ensembl chr10:82,800,704...82,816,731 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha decreases expression EXP Haloperidol results in decreased expression of PPP2CA mRNA CTD PMID:15860345 NCBI chr10:37,534,449...37,554,861
Ensembl chr10:37,535,871...37,554,664 		JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta decreases expression EXP Haloperidol results in decreased expression of PPP2CB mRNA CTD PMID:15860345 NCBI chr16:62,273,276...62,294,767
Ensembl chr16:62,273,276...62,294,769 		JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha increases expression EXP Haloperidol results in increased expression of PPP2R1A mRNA CTD PMID:15860345 NCBI chr 1:60,717,386...60,736,629
Ensembl chr 1:60,717,386...60,736,609 		JBrowse link
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha decreases expression EXP Haloperidol results in decreased expression of PPP2R2A mRNA CTD PMID:15860345 NCBI chr15:43,673,958...43,733,182
Ensembl chr15:43,673,960...43,733,182 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha multiple interactions
decreases expression		 EXP [Haloperidol binds to and results in decreased activity of DRD2 protein] which results in increased expression of PPP3CA protein
Haloperidol results in decreased expression of PPP3CA mRNA; Haloperidol results in decreased expression of PPP3CA protein		 CTD PMID:16033416 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854 		JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit decreases expression ISO Haloperidol results in decreased expression of PPP5C mRNA CTD PMID:14647396 NCBI chr 1:78,944,054...78,968,361
Ensembl chr 1:78,944,040...78,968,329 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha increases expression EXP Haloperidol results in increased expression of PRKACA mRNA CTD PMID:15860345 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta increases expression EXP Haloperidol results in increased expression of PRKACB mRNA CTD PMID:15860345 NCBI chr 2:252,602,197...252,691,886
Ensembl chr 2:252,605,307...252,691,886 		JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha multiple interactions
increases expression		 EXP Haloperidol promotes the reaction [Cyclic AMP binds to PRKAR2A protein]
Haloperidol results in increased expression of PRKAR2A mRNA; Haloperidol results in increased expression of PRKAR2A protein		 CTD PMID:11907174 NCBI chr 8:117,486,085...117,548,768
Ensembl chr 8:117,486,083...117,546,370 		JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta multiple interactions
increases expression
decreases expression		 EXP Haloperidol promotes the reaction [Cyclic AMP binds to PRKAR2B protein]
Haloperidol results in increased expression of PRKAR2B mRNA; Haloperidol results in increased expression of PRKAR2B protein
Haloperidol results in decreased expression of PRKAR2B mRNA		 CTD PMID:11907174 PMID:15860345 NCBI chr 6:51,265,509...51,356,383
Ensembl chr 6:51,265,515...51,356,383 		JBrowse link
G Prkcb protein kinase C, beta multiple interactions
increases expression		 EXP [Haloperidol co-treated with Fluvoxamine] affects the expression of PRKCB protein
Haloperidol results in increased expression of PRKCB mRNA		 CTD PMID:15860345 PMID:15967061 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831 		JBrowse link
G Prkce protein kinase C, epsilon increases expression EXP Haloperidol results in increased expression of PRKCE mRNA CTD PMID:15860345 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396 		JBrowse link
G Prkcz protein kinase C, zeta increases expression EXP Haloperidol results in increased expression of PRKCZ mRNA CTD PMID:15860345 NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421 		JBrowse link
G Prl prolactin affects expression
increases secretion
multiple interactions
increases expression		 ISO
EXP		 Haloperidol affects the expression of PRL protein
Haloperidol results in increased secretion of PRL protein
Haloperidol inhibits the reaction [Aripiprazole results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [cabergoline results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [Dopamine results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [talipexole results in decreased secretion of PRL protein]; LHRH, N-acetyl-(4-chlorophenylalanyl)(1)-(4-chlorophenylalanyl)(2)-tryptophyl(3)-arginyl(6)-alanine(10)- inhibits the reaction [Haloperidol results in increased expression of PRL protein]; Triptorelin Pamoate inhibits the reaction [Haloperidol results in increased expression of PRL protein]		 CTD PMID:1304992 PMID:1380082 PMID:2136057 PMID:3019639 PMID:3158510 PMID:3883215 PMID:3906589 PMID:7018927 PMID:7214106 PMID:7348089 PMID:7670571 PMID:8613910 PMID:8915564 PMID:9090331 PMID:9128918 PMID:9265911 PMID:9265916 PMID:9376336 PMID:9572212 PMID:10661492 PMID:11048906 PMID:11071396 PMID:11997696 PMID:15289996 PMID:15638391 PMID:16282852 PMID:18521575 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299 		JBrowse link
G Prpf38b pre-mRNA processing factor 38B decreases expression ISO Haloperidol results in decreased expression of PRPF38B mRNA CTD PMID:14647396 NCBI chr 2:211,706,245...211,715,271
Ensembl chr 2:211,706,228...211,715,311 		JBrowse link
G Prrc2a proline-rich coiled-coil 2A decreases expression ISO Haloperidol results in decreased expression of PRRC2A mRNA CTD PMID:18797397 NCBI chr20:5,139,881...5,155,371
Ensembl chr20:5,139,882...5,155,293 		JBrowse link
G Psmb9 proteasome 20S subunit beta 9 decreases expression EXP Haloperidol results in decreased expression of PSMB9 mRNA CTD PMID:16452686 NCBI chr20:3,973,424...3,978,845
Ensembl chr20:3,973,420...3,978,845 		JBrowse link
G Ptms parathymosin increases expression ISO Haloperidol results in increased expression of PTMS mRNA CTD PMID:14647396 NCBI chr 4:157,435,371...157,439,507
Ensembl chr 4:157,435,373...157,439,507 		JBrowse link
G Pvalb parvalbumin multiple interactions EXP Haloperidol inhibits the reaction [Phencyclidine results in decreased expression of PVALB mRNA] CTD PMID:12589379 NCBI chr 7:119,428,657...119,443,674
Ensembl chr 7:119,429,019...119,441,487 		JBrowse link
G Qk quaking increases expression ISO Haloperidol results in increased expression of QKI mRNA alternative form CTD PMID:19335891 NCBI chr 1:50,983,647...51,050,692 JBrowse link
G Rab10 RAB10, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB10 mRNA CTD PMID:15860345 NCBI chr 6:27,668,387...27,721,120
Ensembl chr 6:27,668,403...27,721,120 		JBrowse link
G Rab11a RAB11a, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB11A mRNA CTD PMID:15860345 NCBI chr 8:70,192,975...70,215,719
Ensembl chr 8:70,192,975...70,215,719 		JBrowse link
G Rab12 RAB12, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB12 mRNA CTD PMID:12437575 NCBI chr 9:114,683,985...114,709,613
Ensembl chr 9:114,684,039...114,709,546 		JBrowse link
G Rab28 RAB28, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB28 mRNA CTD PMID:15860345 NCBI chr14:73,888,968...73,963,209
Ensembl chr14:73,889,213...73,963,202 		JBrowse link
G Rab4a RAB4A, member RAS oncogene family decreases expression EXP Haloperidol results in decreased expression of RAB4A mRNA CTD PMID:15860345 NCBI chr19:56,585,598...56,613,078
Ensembl chr19:56,585,767...56,613,075 		JBrowse link
G Rab6a RAB6A, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB6A mRNA CTD PMID:15860345 NCBI chr 1:165,624,973...165,664,201
Ensembl chr 1:165,625,058...165,664,192 		JBrowse link
G Rab7a RAB7A, member RAS oncogene family decreases expression EXP Haloperidol results in decreased expression of RAB7A mRNA CTD PMID:15860345 NCBI chr 4:119,910,461...119,963,065
Ensembl chr 4:119,910,478...119,959,173 		JBrowse link
G Rab8a RAB8A, member RAS oncogene family decreases expression EXP Haloperidol results in decreased expression of RAB8A mRNA CTD PMID:15860345 NCBI chr16:19,355,047...19,376,776
Ensembl chr16:19,355,048...19,376,776 		JBrowse link
G Rac1 Rac family small GTPase 1 increases expression EXP Haloperidol results in increased expression of RAC1 mRNA CTD PMID:15860345 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873 		JBrowse link
G Rala RAS like proto-oncogene A increases expression EXP Haloperidol results in increased expression of RALA mRNA CTD PMID:15860345 NCBI chr17:49,676,073...49,729,133
Ensembl chr17:49,714,294...49,727,664 		JBrowse link
G Ralb RAS like proto-oncogene B increases expression EXP Haloperidol results in increased expression of RALB mRNA CTD PMID:15860345 NCBI chr13:35,494,716...35,531,503
Ensembl chr13:35,494,721...35,511,020 		JBrowse link
G Rap1b RAP1B, member of RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAP1B mRNA CTD PMID:15860345 NCBI chr 7:60,850,406...60,878,226
Ensembl chr 7:60,853,930...60,860,990 		JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 decreases expression ISO Haloperidol results in decreased expression of RAPGEF4 mRNA CTD PMID:18797397 NCBI chr 3:58,632,338...58,925,127
Ensembl chr 3:58,632,476...58,924,038 		JBrowse link
G Rarb retinoic acid receptor, beta increases expression EXP Haloperidol results in increased expression of RARB mRNA alternative form CTD PMID:11564422 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599 		JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 affects localization EXP Haloperidol affects the localization of RASGRF1 protein CTD PMID:17092607 NCBI chr 8:97,277,250...97,405,095
Ensembl chr 8:97,277,456...97,405,102 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 decreases expression EXP Haloperidol results in decreased expression of RASGRP1 mRNA CTD PMID:15860345 NCBI chr 3:108,984,029...109,044,420
Ensembl chr 3:108,984,029...109,044,420 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression EXP Haloperidol results in increased expression of RELA protein CTD PMID:18554768 PMID:18590723 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249 		JBrowse link
G Reln reelin decreases expression EXP Haloperidol results in decreased expression of RELN mRNA; Haloperidol results in decreased expression of RELN protein CTD PMID:19359144 NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression EXP Haloperidol results in increased expression of RGS2 mRNA CTD PMID:11409749 PMID:11516571 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 increases expression EXP Haloperidol results in increased expression of RGS4 mRNA CTD PMID:15860345 NCBI chr13:88,054,817...88,061,108
Ensembl chr13:88,054,817...88,061,108 		JBrowse link
G Rgs8 regulator of G-protein signaling 8 increases expression EXP Haloperidol results in increased expression of RGS8 mRNA CTD PMID:15860345 NCBI chr13:71,086,654...71,141,820
Ensembl chr13:71,086,745...71,141,075 		JBrowse link
G Rgs9 regulator of G-protein signaling 9 affects response to substance ISO RGS9 affects the susceptibility to Haloperidol CTD PMID:15728856 NCBI chr10:97,509,971...97,582,188
Ensembl chr10:97,509,971...97,582,188 		JBrowse link
G Rhoa ras homolog family member A decreases expression EXP Haloperidol results in decreased expression of RHOA mRNA CTD PMID:15860345 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167 		JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 decreases expression EXP Haloperidol results in decreased expression of RIMS1 mRNA CTD PMID:15860345 NCBI chr 9:28,440,408...28,973,246
Ensembl chr 9:28,442,229...28,973,246 		JBrowse link
G Rorb RAR-related orphan receptor B decreases expression EXP Haloperidol results in decreased expression of RORB mRNA CTD PMID:11564422 NCBI chr 1:234,252,757...234,442,597
Ensembl chr 1:234,252,757...234,435,839 		JBrowse link
G Rplp2 ribosomal protein lateral stalk subunit P2 increases expression ISO Haloperidol results in increased expression of RPLP2 mRNA CTD PMID:14647396 NCBI chr 1:214,428,280...214,430,551
Ensembl chr 1:214,428,526...214,430,515 		JBrowse link
G Rps10 ribosomal protein S10 increases expression ISO Haloperidol results in increased expression of RPS10 mRNA CTD PMID:14647396 NCBI chr20:7,215,762...7,220,331
Ensembl chr20:7,215,774...7,219,548 		JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression EXP Haloperidol results in increased expression of RRAD mRNA CTD PMID:15860345 NCBI chr19:561,696...564,929
Ensembl chr19:561,727...564,930 		JBrowse link
G Rtn4 reticulon 4 decreases expression ISO Haloperidol results in decreased expression of RTN4 mRNA CTD PMID:18797397 NCBI chr14:114,126,931...114,174,459
Ensembl chr14:114,126,943...114,174,458 		JBrowse link
G Rxrg retinoid X receptor gamma affects response to substance
increases expression		 ISO
EXP		 RXRG protein affects the susceptibility to Haloperidol
Haloperidol results in increased expression of RXRG mRNA alternative form		 CTD PMID:10336693 PMID:11564422 NCBI chr13:85,818,473...85,868,555
Ensembl chr13:85,818,427...85,868,552 		JBrowse link
G S100a9 S100 calcium binding protein A9 decreases expression ISO Haloperidol results in decreased expression of S100A9 mRNA CTD PMID:18797397 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276 		JBrowse link
G Sc5d sterol-C5-desaturase increases expression ISO Haloperidol results in increased expression of SC5D mRNA CTD PMID:17052361 NCBI chr 8:46,525,406...46,537,014
Ensembl chr 8:46,525,400...46,537,050 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO Haloperidol results in increased expression of SCD mRNA CTD PMID:16027736 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729 		JBrowse link
G Serpini1 serpin family I member 1 decreases expression ISO Haloperidol results in decreased expression of SERPINI1 mRNA CTD PMID:18797397 NCBI chr 2:174,013,058...174,111,693
Ensembl chr 2:174,013,288...174,111,752 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression EXP Haloperidol results in increased expression of SGK1 mRNA CTD PMID:16452686 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298 		JBrowse link
G Slc17a6 solute carrier family 17 member 6 increases expression ISO Haloperidol results in increased expression of SLC17A6 mRNA; Haloperidol results in increased expression of SLC17A6 protein CTD PMID:18155072 NCBI chr 1:106,980,463...107,038,717
Ensembl chr 1:106,998,623...107,038,704 		JBrowse link
G Slc17a8 solute carrier family 17 member 8 affects response to substance ISO SLC17A8 protein affects the susceptibility to Haloperidol CTD PMID:18278042 NCBI chr 7:30,215,231...30,274,993
Ensembl chr 7:30,216,104...30,274,984 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 affects binding ISO Haloperidol binds to SLC18A2 protein CTD PMID:7912402 NCBI chr 1:280,397,831...280,457,968
Ensembl chr 1:280,423,079...280,457,148 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 decreases expression EXP Haloperidol results in decreased expression of SLC1A1 mRNA CTD PMID:12873733 NCBI chr 1:246,955,017...247,035,159
Ensembl chr 1:246,954,980...247,037,056 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 decreases expression EXP Haloperidol results in decreased expression of SLC1A2 mRNA CTD PMID:12873733 NCBI chr 3:92,518,679...92,665,731
Ensembl chr 3:92,640,752...92,665,644 		JBrowse link
G Slc1a3 solute carrier family 1 member 3 decreases expression EXP Haloperidol results in decreased expression of SLC1A3 mRNA CTD PMID:15860345 NCBI chr 2:57,860,881...57,935,363
Ensembl chr 2:57,860,834...57,935,363 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Haloperidol inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO Haloperidol results in increased expression of SLC2A4 mRNA CTD PMID:16002093 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487 		JBrowse link
G Slc39a7 solute carrier family 39 member 7 increases expression ISO Haloperidol results in increased expression of SLC39A7 mRNA CTD PMID:14647396 NCBI chr20:3,819,416...3,822,788
Ensembl chr20:3,819,414...3,822,778 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions
increases expression		 ISO
EXP		 SLC6A3 protein promotes the reaction [Haloperidol results in increased expression of NTS mRNA]
Haloperidol results in increased expression of SLC6A3 protein		 CTD PMID:14698760 PMID:17069804 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 increases expression EXP Haloperidol results in increased expression of SLC6A4 CTD PMID:12007678 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463 		JBrowse link
G Snap25 synaptosome associated protein 25 affects response to substance
affects expression		 ISO
EXP		 SNAP25 gene SNP affects the susceptibility to Haloperidol
Haloperidol affects the expression of SNAP25 mRNA		 CTD PMID:15823421 PMID:15860345 NCBI chr 3:129,697,408...129,788,417
Ensembl chr 3:129,599,353...129,788,400 		JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide increases expression ISO Haloperidol results in increased expression of SNRPD2 mRNA CTD PMID:14647396 NCBI chr 1:80,057,140...80,059,990
Ensembl chr 1:80,056,755...80,059,996 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression
decreases expression
multiple interactions		 EXP Haloperidol results in increased expression of SOD1 mRNA
Haloperidol results in decreased expression of SOD1 protein
Clozapine inhibits the reaction [Haloperidol results in decreased expression of SOD1 protein]; Haloperidol results in decreased activity of and results in decreased expression of SOD1 protein; olanzapine inhibits the reaction [Haloperidol results in decreased expression of SOD1 protein]; Risperidone inhibits the reaction [Haloperidol results in decreased expression of SOD1 protein]		 CTD PMID:12482469 PMID:12752374 PMID:16564057 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862 		JBrowse link
G Sod2 superoxide dismutase 2 decreases expression
multiple interactions		 EXP Haloperidol results in decreased expression of SOD2 mRNA; Haloperidol results in decreased expression of SOD2 protein
Haloperidol results in decreased activity of and results in decreased expression of SOD2 protein		 CTD PMID:12482469 PMID:15860345 PMID:16564057 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587 		JBrowse link
G Sod3 superoxide dismutase 3 increases expression EXP Haloperidol results in increased expression of SOD3 mRNA CTD PMID:15860345 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO Haloperidol results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:17052361 NCBI chr 7:123,381,082...123,438,605
Ensembl chr 7:123,381,077...123,438,603 		JBrowse link
G Strn4 striatin 4 increases expression ISO Haloperidol results in increased expression of STRN4 mRNA CTD PMID:14647396 NCBI chr 1:78,739,930...78,765,696
Ensembl chr 1:78,735,678...78,765,692 		JBrowse link
G Stx1a syntaxin 1A increases expression EXP Haloperidol results in increased expression of STX1A mRNA CTD PMID:15860345 NCBI chr12:24,682,050...24,710,002
Ensembl chr12:24,682,041...24,710,019 		JBrowse link
G Stx1b syntaxin 1B affects expression EXP Haloperidol affects the expression of STX1B mRNA CTD PMID:15860345 NCBI chr 1:199,251,842...199,270,465
Ensembl chr 1:199,251,844...199,270,627 		JBrowse link
G Stx4 syntaxin 4 increases expression EXP Haloperidol results in increased expression of STX4 mRNA CTD PMID:15860345 NCBI chr 1:199,287,384...199,295,606
Ensembl chr 1:199,287,710...199,294,979 		JBrowse link
G Stx5 syntaxin 5 decreases expression EXP Haloperidol results in decreased expression of STX5 mRNA CTD PMID:15860345 NCBI chr 1:224,939,497...224,955,658
Ensembl chr 1:224,939,497...224,955,657 		JBrowse link
G Stx7 syntaxin 7 decreases expression EXP Haloperidol results in decreased expression of STX7 mRNA CTD PMID:15860345 NCBI chr 1:22,241,655...22,281,850
Ensembl chr 1:22,241,661...22,281,788 		JBrowse link
G Stx8 syntaxin 8 affects expression EXP Haloperidol affects the expression of STX8 mRNA CTD PMID:15860345 NCBI chr10:54,512,922...54,753,302
Ensembl chr10:54,512,983...54,753,302 		JBrowse link
G Supt3h SPT3 homolog, SAGA and STAGA complex component increases expression EXP Haloperidol results in increased expression of SUPT3H mRNA CTD PMID:16715494 NCBI chr 9:18,249,565...18,604,814
Ensembl chr 9:18,319,246...18,371,856 		JBrowse link
G Syn2 synapsin II increases expression EXP Haloperidol results in increased expression of SYN2 mRNA CTD PMID:15860345 NCBI chr 4:147,037,179...147,195,096
Ensembl chr 4:147,037,179...147,195,096 		JBrowse link
G Sypl1 synaptophysin-like 1 decreases expression ISO Haloperidol results in decreased expression of SYPL mRNA CTD PMID:18797397 NCBI chr 6:52,265,920...52,286,037
Ensembl chr 6:52,265,930...52,285,029 		JBrowse link
G Syt11 synaptotagmin 11 increases expression EXP Haloperidol results in increased expression of SYT11 mRNA CTD PMID:15860345 NCBI chr 2:188,112,301...188,138,180
Ensembl chr 2:188,112,286...188,138,177 		JBrowse link
G Syt3 synaptotagmin 3 decreases expression EXP Haloperidol results in decreased expression of SYT3 mRNA CTD PMID:15860345 NCBI chr 1:100,379,236...100,407,862
Ensembl chr 1:100,379,186...100,408,083 		JBrowse link
G Syt4 synaptotagmin 4 affects expression EXP Haloperidol affects the expression of SYT4 mRNA CTD PMID:15860345 NCBI chr18:24,172,580...24,181,989
Ensembl chr18:24,172,587...24,182,012 		JBrowse link
G Tac1 tachykinin, precursor 1 increases expression EXP Haloperidol results in increased expression of TAC1 mRNA CTD PMID:10974607 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819 		JBrowse link
G Tagln transgelin decreases expression ISO Haloperidol results in decreased expression of TAGLN mRNA CTD PMID:17175557 NCBI chr 8:50,222,895...50,228,369
Ensembl chr 8:50,222,896...50,231,357 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member decreases expression EXP Haloperidol results in decreased expression of TAP1 mRNA CTD PMID:16452686 NCBI chr20:3,979,302...3,989,669
Ensembl chr20:3,979,035...3,989,669 		JBrowse link
G Tatdn1 TatD DNase domain containing 1 increases expression ISO Haloperidol results in increased expression of TATDN1 mRNA CTD PMID:14647396 NCBI chr 7:98,782,164...98,813,001
Ensembl chr 7:98,782,178...98,804,499 		JBrowse link
G Tf transferrin decreases expression ISO Haloperidol results in decreased expression of TRF mRNA CTD PMID:17177202 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333 		JBrowse link
G Th tyrosine hydroxylase increases expression EXP Haloperidol results in increased expression of TH protein CTD PMID:17028028 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287 		JBrowse link
G Thra thyroid hormone receptor alpha decreases expression
increases expression		 EXP Haloperidol results in decreased expression of THRA mRNA alternative form
Haloperidol results in increased expression of THRA mRNA alternative form		 CTD PMID:11564422 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 EXP Haloperidol affects the reaction [Phencyclidine affects the expression of TNF mRNA]
Haloperidol results in increased expression of TNF protein		 CTD PMID:16478754 PMID:18554768 PMID:18590723 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnik TRAF2 and NCK interacting kinase decreases expression ISO Haloperidol results in decreased expression of TNIK mRNA CTD PMID:14647396 NCBI chr 2:113,984,599...114,391,805
Ensembl chr 2:113,984,646...114,384,894 		JBrowse link
G Tor1a torsin family 1, member A affects response to substance ISO TOR1A gene mutant form affects the susceptibility to Haloperidol CTD PMID:20227500 NCBI chr 3:9,800,322...9,807,318
Ensembl chr 3:9,800,322...9,807,328 		JBrowse link
G Tp53 tumor protein p53 increases expression EXP Haloperidol results in increased expression of TP53 mRNA; Haloperidol results in increased expression of TP53 protein CTD PMID:16462815 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression EXP Haloperidol results in increased expression of TPI1 mRNA CTD PMID:15860345 NCBI chr 4:157,328,375...157,331,905
Ensembl chr 4:157,328,379...157,331,905 		JBrowse link
G Trim2 tripartite motif-containing 2 decreases expression ISO Haloperidol results in decreased expression of TRIM2 mRNA CTD PMID:14647396 NCBI chr 2:183,145,096...183,223,819
Ensembl chr 2:183,145,089...183,213,228 		JBrowse link
G Trim23 tripartite motif-containing 23 decreases expression EXP Haloperidol results in decreased expression of TRIM23 mRNA CTD PMID:15860345 NCBI chr 2:34,255,300...34,288,140
Ensembl chr 2:34,255,305...34,288,139 		JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 increases expression ISO Haloperidol results in increased expression of UBA52 mRNA CTD PMID:14647396 NCBI chr16:20,668,925...20,671,127
Ensembl chr16:20,668,971...20,671,127 		JBrowse link
G Ube2r2 ubiquitin-conjugating enzyme E2R 2 increases expression ISO Haloperidol results in increased expression of UBE2R2 mRNA CTD PMID:14647396 NCBI chr 5:57,472,315...57,530,973
Ensembl chr 5:57,472,315...57,530,987 		JBrowse link
G Ugt8 UDP glycosyltransferase 8 decreases expression ISO Haloperidol results in decreased expression of UGT8A mRNA CTD PMID:17177202 NCBI chr 2:229,644,373...229,718,678
Ensembl chr 2:229,644,382...229,718,659 		JBrowse link
G Unc13a unc-13 homolog A decreases expression EXP Haloperidol results in decreased expression of UNC13A mRNA CTD PMID:15860345 NCBI chr16:20,056,398...20,103,951
Ensembl chr16:20,056,765...20,097,287 		JBrowse link
G Uqcr11 ubiquinol-cytochrome c reductase, complex III subunit XI increases expression ISO Haloperidol results in increased expression of UQCR11 mRNA CTD PMID:14647396 NCBI chr 7:12,171,146...12,175,838
Ensembl chr 7:12,171,185...12,175,835 		JBrowse link
G Vamp1 vesicle-associated membrane protein 1 decreases expression
increases expression		 EXP Haloperidol results in decreased expression of VAMP1 mRNA
Haloperidol results in increased expression of VAMP1 mRNA		 CTD PMID:15860345 NCBI chr 4:157,726,941...157,733,644
Ensembl chr 4:157,726,941...157,733,643 		JBrowse link
G Vamp2 vesicle-associated membrane protein 2 decreases expression
increases expression		 EXP Haloperidol results in decreased expression of VAMP2 mRNA
Haloperidol results in increased expression of VAMP2 mRNA		 CTD PMID:15860345 NCBI chr10:55,675,171...55,679,405
Ensembl chr10:55,675,575...55,679,450 		JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 decreases expression ISO Haloperidol results in decreased expression of VIPR2 mRNA CTD PMID:27900577 NCBI chr 6:143,932,960...144,009,476
Ensembl chr 6:143,938,040...144,008,072 		JBrowse link
G Vldlr very low density lipoprotein receptor increases expression EXP Haloperidol results in increased expression of VLDLR protein CTD PMID:19359144 NCBI chr 1:245,236,819...245,273,688
Ensembl chr 1:245,237,736...245,269,205 		JBrowse link
G Vsnl1 visinin-like 1 decreases expression EXP Haloperidol results in decreased expression of VSNL1 mRNA CTD PMID:12437575 NCBI chr 6:37,001,360...37,121,969
Ensembl chr 6:37,001,356...37,122,023 		JBrowse link
G Wbp1l WW domain binding protein 1-like decreases expression ISO Haloperidol results in decreased expression of WBP1L mRNA CTD PMID:14647396 NCBI chr 1:266,358,728...266,415,296
Ensembl chr 1:266,358,728...266,415,296 		JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 increases expression ISO Haloperidol results in increased expression of WIPI1 mRNA CTD PMID:17175557 NCBI chr10:97,859,730...97,896,949
Ensembl chr10:97,859,727...97,896,525 		JBrowse link
miglustat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO miglustat inhibits the reaction [ST8SIA1 protein results in increased expression of BCL2 protein] CTD PMID:11574545 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Canx calnexin multiple interactions ISO miglustat inhibits the reaction [CANX protein binds to CFTR protein mutant form] CTD PMID:18230692 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861 		JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions
increases activity		 ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat results in increased activity of CFTR protein mutant form]; Brefeldin A inhibits the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Brefeldin A inhibits the reaction [miglustat results in increased activity of CFTR protein mutant form]; geldanamycin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; geldanamycin promotes the reaction [miglustat results in increased activity of CFTR protein mutant form]; miglustat inhibits the reaction [CANX protein binds to CFTR protein mutant form]; miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; Thapsigargin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Thapsigargin promotes the reaction [miglustat results in increased activity of CFTR protein mutant form] CTD PMID:18230692 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676 		JBrowse link
G Pawr pro-apoptotic WT1 regulator multiple interactions ISO miglustat inhibits the reaction [[ST8SIA1 protein affects the abundance of Gangliosides] which results in decreased expression of PAWR protein] CTD PMID:11574545 NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068 		JBrowse link
G St8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 multiple interactions ISO miglustat inhibits the reaction [[ST8SIA1 protein affects the abundance of Gangliosides] which results in decreased expression of PAWR protein]; miglustat inhibits the reaction [ST8SIA1 protein results in increased expression of BCL2 protein] CTD PMID:11574545 NCBI chr 4:177,065,266...177,195,942
Ensembl chr 4:177,065,168...177,196,180 		JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase multiple interactions ISO [miglustat results in decreased activity of UGCG protein] which results in decreased abundance of Gangliosides; [miglustat results in decreased activity of UGCG protein] which results in decreased abundance of Glucosylceramides CTD PMID:10037475 NCBI chr 5:76,376,722...76,419,564
Ensembl chr 5:76,386,836...76,419,560 		JBrowse link
periciazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO periciazine binds to and results in decreased activity of AR protein CTD PMID:17606915 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO periciazine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19875
    chemical entity 19875
      atom 19873
        nonmetal atom 19751
          nitrogen atom 18640
            nitrogen molecular entity 18640
              organonitrogen compound 18414
                organonitrogen heterocyclic compound 17579
                  piperidines 7567
                    hydroxypiperidine 417
                      (2E,3S)-3-hydroxy-5'-[(4-hydroxypiperidin-1-yl)sulfonyl]-3-methyl-1,3-dihydro-2,3'-biindol-2'(1'H)-one 0
                      (2R,3R,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)piperidin-3-yl hexopyranoside 0
                      (2R,3R,4R,5S,6Z)-4,5-dihydroxy-6-(hydroxyimino)-2-(hydroxymethyl)piperidin-3-yl 4-O-methyl-alpha-D-maltoside 0
                      (2R,3R,4R,5S,6Z)-4,5-dihydroxy-6-(hydroxyimino)-2-(hydroxymethyl)piperidin-3-yl alpha-D-maltoside 0
                      (2S)-[(2S,3S,4S,5S)-1,3,4,5-tetrahydroxy-4-(hydroxymethyl)piperidin-2-yl](L-tyrosylamino)acetic acid + 0
                      (2S,3R)-2-[(3S,6R)-3-amino-6-hydroxy-2-oxopiperidinyl]-3-hydroxybutanoic acid 0
                      (2S,3R,4S,5R)-2-methylpiperidine-3,4,5-triol 0
                      (2Z,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)piperidin-2-one oxime 0
                      (3R,4R)-piperidine-3,4-diol 0
                      (3R,4R,5R)-3-hydroxy-5-(hydroxymethyl)piperidin-4-yl beta-D-glucopyranoside 0
                      (3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)piperidin-3-yl beta-D-glucopyranoside 0
                      (3R,4R,5R)-5-(hydroxymethyl)-1-(3-phenylpropyl)piperidine-3,4-diol 0
                      (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol 0
                      (3R,4r,5S)-piperidine-3,4,5-triol 0
                      (3S)-3-hydroxypiperidin-2-one 0
                      (3S,4R)-3-hydroxy-2-oxopiperidin-4-yl beta-D-xylopyranoside 0
                      (3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)piperidin-2-one 0
                      1-\{4-[4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]benzyl\}piperidin-4-ol 0
                      2-(hydroxymethyl)piperidine-3,4,5-triol + 26
                      3,4,5-trihydroxypiperidin-2-one oxime 0
                      3-epi-fagomine 0
                      4-(4-chlorophenyl)-1-\{3-[2-(4-fluorophenyl)-1,3-dithiolan-2-yl]propyl\}piperidin-4-ol 0
                      5-(hydroxymethyl)piperidine-2,3,4-triol + 0
                      5-chloro-N-[(1S)-1-(4-fluorobenzyl)-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-1H-indole-2-carboxamide 0
                      N-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)piperidin-2-yl]acetamide 0
                      N-\{(3R,4R)-4-[(\{4-[(2-hydroxy-5-piperidin-1-ylphenyl)carbonyl]phenyl\}carbonyl)amino]azepan-3-yl\}isonicotinamide 0
                      N-\{5-[(7-\{[(2S)-2-hydroxy-3-piperidin-1-ylpropyl]oxy\}-6-methoxyquinazolin-4-yl)amino]pyrimidin-2-yl\}benzamide 0
                      N-nonyldeoxynojirimycin 0
                      alvocidib 68
                      deoxyfuconojirimycin 0
                      haloperidol 342
                      nadifloxacin + 0
                      nojirimycin 0
                      periciazine 2
                      prosopinine 0
                      rohitukine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19875
    subatomic particle 19873
      composite particle 19873
        hadron 19873
          baryon 19873
            nucleon 19873
              atomic nucleus 19873
                atom 19873
                  main group element atom 19763
                    p-block element atom 19763
                      carbon group element atom 19668
                        carbon atom 19657
                          organic molecular entity 19657
                            organic molecule 19586
                              organic cyclic compound 19395
                                organic heterocyclic compound 18511
                                  organic heteromonocyclic compound 16621
                                    piperidines 7567
                                      hydroxypiperidine 417
                                        (2E,3S)-3-hydroxy-5'-[(4-hydroxypiperidin-1-yl)sulfonyl]-3-methyl-1,3-dihydro-2,3'-biindol-2'(1'H)-one 0
                                        (2R,3R,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)piperidin-3-yl hexopyranoside 0
                                        (2R,3R,4R,5S,6Z)-4,5-dihydroxy-6-(hydroxyimino)-2-(hydroxymethyl)piperidin-3-yl 4-O-methyl-alpha-D-maltoside 0
                                        (2R,3R,4R,5S,6Z)-4,5-dihydroxy-6-(hydroxyimino)-2-(hydroxymethyl)piperidin-3-yl alpha-D-maltoside 0
                                        (2S)-[(2S,3S,4S,5S)-1,3,4,5-tetrahydroxy-4-(hydroxymethyl)piperidin-2-yl](L-tyrosylamino)acetic acid + 0
                                        (2S,3R)-2-[(3S,6R)-3-amino-6-hydroxy-2-oxopiperidinyl]-3-hydroxybutanoic acid 0
                                        (2S,3R,4S,5R)-2-methylpiperidine-3,4,5-triol 0
                                        (2Z,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)piperidin-2-one oxime 0
                                        (3R,4R)-piperidine-3,4-diol 0
                                        (3R,4R,5R)-3-hydroxy-5-(hydroxymethyl)piperidin-4-yl beta-D-glucopyranoside 0
                                        (3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)piperidin-3-yl beta-D-glucopyranoside 0
                                        (3R,4R,5R)-5-(hydroxymethyl)-1-(3-phenylpropyl)piperidine-3,4-diol 0
                                        (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol 0
                                        (3R,4r,5S)-piperidine-3,4,5-triol 0
                                        (3S)-3-hydroxypiperidin-2-one 0
                                        (3S,4R)-3-hydroxy-2-oxopiperidin-4-yl beta-D-xylopyranoside 0
                                        (3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)piperidin-2-one 0
                                        1-\{4-[4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]benzyl\}piperidin-4-ol 0
                                        2-(hydroxymethyl)piperidine-3,4,5-triol + 26
                                        3,4,5-trihydroxypiperidin-2-one oxime 0
                                        3-epi-fagomine 0
                                        4-(4-chlorophenyl)-1-\{3-[2-(4-fluorophenyl)-1,3-dithiolan-2-yl]propyl\}piperidin-4-ol 0
                                        5-(hydroxymethyl)piperidine-2,3,4-triol + 0
                                        5-chloro-N-[(1S)-1-(4-fluorobenzyl)-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-1H-indole-2-carboxamide 0
                                        N-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)piperidin-2-yl]acetamide 0
                                        N-\{(3R,4R)-4-[(\{4-[(2-hydroxy-5-piperidin-1-ylphenyl)carbonyl]phenyl\}carbonyl)amino]azepan-3-yl\}isonicotinamide 0
                                        N-\{5-[(7-\{[(2S)-2-hydroxy-3-piperidin-1-ylpropyl]oxy\}-6-methoxyquinazolin-4-yl)amino]pyrimidin-2-yl\}benzamide 0
                                        N-nonyldeoxynojirimycin 0
                                        alvocidib 68
                                        deoxyfuconojirimycin 0
                                        haloperidol 342
                                        nadifloxacin + 0
                                        nojirimycin 0
                                        periciazine 2
                                        prosopinine 0
                                        rohitukine 0
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