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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:hydroxypiperidine
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Accession:CHEBI:48590 term browser browse the term
Synonyms:related_synonym: hydroxypiperidines



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4-hydroxy-TEMPO term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP tempol inhibits the reaction [Aldosterone results in increased expression of ACTA2 protein] CTD PMID:25204689 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Agt angiotensinogen multiple interactions EXP
ISO
tempol inhibits the reaction [AGT protein modified form results in increased expression of S1PR1 mRNA]; tempol inhibits the reaction [AGT protein modified form results in increased expression of S1PR1 protein]; tempol inhibits the reaction [AGT protein results in decreased export of Sodium]; tempol inhibits the reaction [AGT protein results in increased abundance of Oxygen]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]
tempol inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA]; tempol inhibits the reaction [AGT protein modified form results in increased abundance of Superoxides]; tempol inhibits the reaction [AGT protein results in increased expression of EDN1 mRNA]; tempol inhibits the reaction [ATP7A mutant form inhibits the reaction [AGT protein results in increased susceptibility to Acetylcholine]]; tempol inhibits the reaction [ATP7A mutant form promotes the reaction [AGT protein results in increased abundance of Superoxides]]; tempol promotes the reaction [ATOX1 protein inhibits the reaction [AGT protein modified form results in decreased susceptibility to Acetylcholine]]
CTD PMID:14597645 PMID:17391658 PMID:17620961 PMID:18250367 PMID:18768397 More... NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions ISO tempol inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA] CTD PMID:17620961 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agtr1b angiotensin II receptor, type 1b multiple interactions ISO tempol inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA] CTD PMID:17620961 NCBI chr 2:102,844,969...102,920,232
Ensembl chr 2:102,844,969...102,920,232
JBrowse link
G Akt1 AKT serine/threonine kinase 1 affects phosphorylation ISO tempol affects the phosphorylation of AKT1 protein CTD PMID:24550650 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Apoe apolipoprotein E multiple interactions ISO tempol inhibits the reaction [APOE gene mutant form results in decreased susceptibility to Arachidonic Acid]
tempol inhibits the reaction [APOE gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]]
CTD PMID:20530721 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Atox1 antioxidant 1 copper chaperone multiple interactions ISO tempol promotes the reaction [ATOX1 protein inhibits the reaction [AGT protein modified form results in decreased susceptibility to Acetylcholine]] CTD PMID:22753205 NCBI chr10:39,564,855...39,579,892
Ensembl chr10:39,564,857...39,579,950
JBrowse link
G Atp7a ATPase copper transporting alpha multiple interactions ISO tempol inhibits the reaction [ATP7A mutant form inhibits the reaction [AGT protein results in increased susceptibility to Acetylcholine]]; tempol inhibits the reaction [ATP7A mutant form promotes the reaction [AGT protein results in increased abundance of Superoxides]] CTD PMID:18768397 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects expression
decreases expression
ISO
EXP
tempol affects the expression of BAX protein
tempol results in decreased expression of BAX protein
CTD PMID:18714161 PMID:24550650 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression ISO tempol affects the expression of BCL2 protein CTD PMID:24550650 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G C1qa complement C1q A chain decreases expression ISO tempol results in decreased expression of C1QA mRNA CTD PMID:19555370 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534
JBrowse link
G C4b complement C4B (Chido blood group) decreases expression ISO tempol results in decreased expression of C4B mRNA CTD PMID:19555370 NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681
JBrowse link
G Casp1 caspase 1 multiple interactions ISO tempol inhibits the reaction [7-ketocholesterol results in increased activity of CASP1 protein]; tempol inhibits the reaction [Cholesterol analog results in increased activity of CASP1 protein] CTD PMID:28633109 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression
ISO
EXP
[tempol co-treated with UCF 101 co-treated with acetovanillone] inhibits the reaction [S-Nitrosoglutathione results in increased activity of CASP3 protein]; tempol inhibits the reaction [[sulindac sulfide co-treated with TNF protein] results in increased activity of CASP3 protein]
tempol results in decreased expression of CASP3 protein
CTD PMID:18714161 PMID:20153346 PMID:20371263 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions ISO tempol inhibits the reaction [[sulindac sulfide co-treated with TNF protein] results in increased activity of CASP7 protein]; tempol results in increased cleavage of and results in increased activity of CASP7 protein CTD PMID:20371263 PMID:26177467 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp9 caspase 9 decreases expression EXP tempol results in decreased expression of CASP9 protein CTD PMID:18714161 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions EXP CAT protein results in increased susceptibility to [tert-Butylhydroperoxide co-treated with Desoxycorticosterone co-treated with tempol] CTD PMID:12646410 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression EXP tempol results in decreased expression of CCN2 mRNA CTD PMID:16685210 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO tempol results in decreased expression of CCND1 protein CTD PMID:26177467 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cd38 CD38 molecule multiple interactions ISO tempol inhibits the reaction [Superoxides affects the localization of CD38 protein] CTD PMID:23940720 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO tempol promotes the reaction [CDKN1A protein results in increased susceptibility to Doxorubicin]
tempol results in increased expression of CDKN1A protein
CTD PMID:15601469 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Ctss cathepsin S decreases expression ISO tempol results in decreased expression of CTSS mRNA CTD PMID:19555370 NCBI chr 2:183,089,192...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 decreases expression ISO tempol results in decreased expression of CXCL14 mRNA CTD PMID:19555370 NCBI chr17:8,317,933...8,325,956
Ensembl chr17:8,317,933...8,324,839
JBrowse link
G Cyba cytochrome b-245 alpha chain decreases expression EXP tempol results in decreased expression of CYBA mRNA CTD PMID:16685210 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cybb cytochrome b-245 beta chain decreases expression EXP tempol results in decreased expression of CYBB; tempol results in decreased expression of CYBB mRNA CTD PMID:16685210 PMID:20943769 NCBI chr  X:13,360,583...13,392,517
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP tempol inhibits the reaction [CYP2E1 protein results in increased reduction of Tirapazamine] CTD PMID:7710944 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Edn1 endothelin 1 decreases expression
multiple interactions
EXP
ISO
tempol results in decreased expression of EDN1 mRNA; tempol results in decreased expression of EDN1 protein
tempol inhibits the reaction [AGT protein results in increased expression of EDN1 mRNA]
CTD PMID:17391658 PMID:28039404 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Epas1 endothelial PAS domain protein 1 affects localization ISO tempol affects the localization of EPAS1 protein CTD PMID:24755467 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Fancd2 FA complementation group D2 decreases response to substance ISO tempol results in decreased susceptibility to FANCD2 gene mutant form CTD PMID:22628295 NCBI chr 4:146,679,014...146,743,422
Ensembl chr 4:146,679,179...146,743,412
JBrowse link
G Foxo3 forkhead box O3 affects phosphorylation ISO tempol affects the phosphorylation of FOXO3 protein CTD PMID:24550650 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP tempol inhibits the reaction [Aldosterone results in increased expression of GCLC protein] CTD PMID:24512358 PMID:25204689 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO [tempol co-treated with Tobacco Smoke Pollution] results in increased expression of GPX2 mRNA; tempol promotes the reaction [Tobacco Smoke Pollution results in increased expression of GPX2 protein] CTD PMID:32726580 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression ISO tempol results in increased expression of GPX4 mRNA CTD PMID:22221582 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP tempol inhibits the reaction [Nitric Oxide deficiency results in increased expression of GSR protein] CTD PMID:15925750 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
EXP tempol inhibits the reaction [Sodium Chloride results in increased expression of HIF1A protein]
tempol results in increased expression of HIF1A protein
CTD PMID:12595275 PMID:20232302 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO tempol inhibits the reaction [Asbestos, Crocidolite results in decreased activity of HMGCR protein]; tempol inhibits the reaction [Vitamin K 3 results in decreased activity of HMGCR protein] CTD PMID:21257924 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
EXP
ISO
tempol results in increased expression of HMOX1 mRNA
[tempol co-treated with Tobacco Smoke Pollution] results in increased expression of HMOX1 mRNA
CTD PMID:12595275 PMID:32726580 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO tempol inhibits the reaction [PRKAA2 protein affects the expression of HSPA5 protein] CTD PMID:21145922 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Htra2 HtrA serine peptidase 2 multiple interactions ISO [tempol co-treated with UCF 101 co-treated with acetovanillone] inhibits the reaction [S-Nitrosoglutathione affects the localization of HTRA2 protein] CTD PMID:20153346 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon decreases expression ISO tempol results in decreased expression of IKBKE protein CTD PMID:26177467 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143
JBrowse link
G Il10 interleukin 10 multiple interactions ISO tempol inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of IL10 mRNA] CTD PMID:32726580 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il17a interleukin 17A multiple interactions ISO tempol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of IL17A mRNA] CTD PMID:32726580 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
tempol inhibits the reaction [Phenol results in decreased expression of IL1B mRNA]
tempol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of IL1B mRNA]
CTD PMID:16785328 PMID:32726580 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO tempol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of IL6 mRNA]
tempol inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of and results in increased secretion of IL6 protein]
CTD PMID:24296301 PMID:32726580 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ireb2 iron responsive element binding protein 2 increases expression ISO tempol results in increased expression of IREB2 protein CTD PMID:18073202 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions ISO tempol inhibits the reaction [Benzene results in decreased phosphorylation of IRS2 protein] CTD PMID:30346588 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO tempol inhibits the reaction [Paraquat results in increased expression of JUN mRNA] CTD PMID:7662713 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO tempol inhibits the reaction [LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]] CTD PMID:20530721 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lep leptin multiple interactions EXP tempol inhibits the reaction [LEP protein results in decreased activity of PON1 protein] CTD PMID:15829432 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lepr leptin receptor multiple interactions ISO tempol inhibits the reaction [LEPR gene mutant form results in decreased susceptibility to Acetylcholine] CTD PMID:19478208 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tempol results in increased phosphorylation of MAPK1 protein] CTD PMID:20056918 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tempol results in increased phosphorylation of MAPK3 protein] CTD PMID:20056918 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mir322 microRNA 322 multiple interactions ISO tempol inhibits the reaction [Glucose results in decreased expression of MIR322] CTD PMID:25516495 NCBI chr  X:132,806,594...132,806,688
Ensembl chr  X:132,806,594...132,806,688
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases activity EXP tempol results in increased activity of MMP2 protein CTD PMID:17196988 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases activity EXP tempol results in increased activity of MMP9 protein CTD PMID:17196988 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO tempol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of and results in increased activity of MPO protein] CTD PMID:32726580 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP tempol inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein] CTD PMID:25204689 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP tempol inhibits the reaction [copper histidine results in increased activity of NFKB1 protein]; tempol inhibits the reaction [Copper results in increased activity of NFKB1 protein] CTD PMID:16987042 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO tempol inhibits the reaction [Particulate Matter results in decreased expression of NFKBIA protein] CTD PMID:27128347 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions
increases phosphorylation
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tempol results in increased phosphorylation of NOS1 protein]; tempol inhibits the reaction [lead acetate results in increased expression of NOS1 protein]; tempol inhibits the reaction [Phenol results in decreased expression of NOS1 mRNA] CTD PMID:11454931 PMID:16785328 PMID:20056918 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP tempol inhibits the reaction [copper histidine results in increased expression of NOS2 protein]; tempol inhibits the reaction [Copper results in increased expression of NOS2 protein]; tempol inhibits the reaction [lead acetate results in increased expression of NOS2 protein] CTD PMID:11454931 PMID:16987042 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions EXP
ISO
tempol inhibits the reaction [lead acetate results in increased expression of NOS3 protein]; tempol inhibits the reaction [Sodium Chloride results in decreased expression of NOS3 protein] CTD PMID:11230275 PMID:11454931 PMID:20232302 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions ISO tempol inhibits the reaction [Paraquat results in increased activity of ODC1 protein] CTD PMID:7662713 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Pah phenylalanine hydroxylase decreases expression ISO tempol results in decreased expression of PAH mRNA CTD PMID:19555370 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 multiple interactions ISO tempol inhibits the reaction [sodium arsenite results in increased expression of PECAM1 protein] CTD PMID:19033667 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Pon1 paraoxonase 1 multiple interactions EXP tempol inhibits the reaction [LEP protein results in decreased activity of PON1 protein] CTD PMID:15829432 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions ISO tempol inhibits the reaction [PRKAA2 protein affects the expression of HSPA5 protein] CTD PMID:21145922 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 multiple interactions EXP tempol inhibits the reaction [Glucose results in decreased expression of PRKG1 protein] CTD PMID:17320767 NCBI chr 1:228,409,883...229,638,794
Ensembl chr 1:228,408,947...229,639,080
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions EXP tempol inhibits the reaction [Ketoconazole results in increased expression of PRKN mRNA]; tempol inhibits the reaction [Ketoconazole results in increased expression of PRKN protein] CTD PMID:25787151 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP tempol inhibits the reaction [copper histidine results in increased expression of PTGS2 mRNA]; tempol inhibits the reaction [Copper results in increased expression of PTGS2 mRNA]; tempol inhibits the reaction [Lead results in increased expression of PTGS2 mRNA]; tempol inhibits the reaction [Mercuric Chloride results in increased expression of PTGS2 mRNA] CTD PMID:16987042 PMID:23415682 PMID:25596430 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
tempol inhibits the reaction [Benzene results in increased phosphorylation of RELA protein]
tempol inhibits the reaction [copper histidine results in increased activity of RELA protein]; tempol inhibits the reaction [Copper results in increased activity of RELA protein]
CTD PMID:16987042 PMID:30346588 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rhoa ras homolog family member A multiple interactions EXP
ISO
tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]
tempol inhibits the reaction [Asbestos, Crocidolite inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]]; tempol inhibits the reaction [Asbestos, Crocidolite results in decreased prenylation of RHOA protein]; tempol inhibits the reaction [Vitamin K 3 inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]]; tempol inhibits the reaction [Vitamin K 3 results in decreased prenylation of RHOA protein]
CTD PMID:18250367 PMID:21257924 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 multiple interactions EXP tempol inhibits the reaction [AGT protein modified form results in increased expression of S1PR1 mRNA]; tempol inhibits the reaction [AGT protein modified form results in increased expression of S1PR1 protein] CTD PMID:29609002 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO tempol inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA]; tempol inhibits the reaction [Hydrogen Peroxide results in increased expression of SERPINE1 mRNA] CTD PMID:17620961 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Skap2 src kinase associated phosphoprotein 2 decreases expression ISO tempol results in decreased expression of SKAP2 mRNA CTD PMID:19555370 NCBI chr 4:80,948,832...81,100,900
Ensembl chr 4:80,950,580...81,100,891
JBrowse link
G Slc12a2 solute carrier family 12 member 2 multiple interactions EXP tempol inhibits the reaction [Manganese results in increased expression of SLC12A2 protein]; tempol inhibits the reaction [Manganese results in increased oxidation of SLC12A2 protein] CTD PMID:25817889 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440
JBrowse link
G Socs1 suppressor of cytokine signaling 1 multiple interactions ISO tempol inhibits the reaction [Benzene results in increased expression of SOCS1 mRNA] CTD PMID:30346588 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP tempol inhibits the reaction [Desoxycorticosterone results in decreased expression of SOD1 protein] CTD PMID:12646410 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 affects expression
multiple interactions
ISO
EXP
tempol affects the expression of SOD2 protein
tempol affects the reaction [SOD2 protein affects the susceptibility to Acetylcholine]; tempol inhibits the reaction [Capsaicin results in decreased activity of SOD2 protein]; tempol inhibits the reaction [Capsaicin results in increased expression of SOD2 protein modified form]
tempol inhibits the reaction [Isoflurane results in decreased expression of and results in decreased activity of SOD2 protein]; tempol inhibits the reaction [Nitric Oxide deficiency results in increased expression of SOD2 protein]
CTD PMID:15925750 PMID:17693941 PMID:19129394 PMID:20304815 PMID:24550650 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tfrc transferrin receptor increases expression ISO tempol results in increased expression of TFRC protein CTD PMID:18073202 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tgfb1 transforming growth factor, beta 1 affects expression
multiple interactions
ISO
EXP
tempol affects the expression of TGFB1 protein
tempol inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of TGFB1 mRNA]
tempol inhibits the reaction [Aldosterone results in increased expression of TGFB1 mRNA]; tempol inhibits the reaction [Sodium Chloride results in increased expression of TGFB1 protein]
CTD PMID:20232302 PMID:24550650 PMID:25204689 PMID:32726580 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
tempol inhibits the reaction [[sulindac sulfide co-treated with TNF protein] results in increased activity of CASP3 protein]; tempol inhibits the reaction [[sulindac sulfide co-treated with TNF protein] results in increased activity of CASP7 protein]
tempol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; tempol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TNF mRNA]
tempol inhibits the reaction [copper histidine results in increased expression of TNF protein]; tempol inhibits the reaction [Copper results in increased expression of TNF protein]
CTD PMID:15795323 PMID:16987042 PMID:20371263 PMID:32726580 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 increases expression ISO tempol results in increased expression of TP53 protein CTD PMID:15601469 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Traf3 Tnf receptor-associated factor 3 multiple interactions ISO tempol inhibits the reaction [Glucose results in increased expression of TRAF3 protein] CTD PMID:25516495 NCBI chr 6:130,199,696...130,307,168
Ensembl chr 6:130,206,484...130,305,481
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 multiple interactions ISO tempol inhibits the reaction [Arsenic Trioxide results in increased expression of TRPM4 protein] CTD PMID:31054354 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532
JBrowse link
G Ucp2 uncoupling protein 2 decreases expression
increases expression
EXP tempol results in decreased expression of UCP2 mRNA
tempol results in increased expression of UCP2 protein
CTD PMID:16685210 PMID:24591154 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
alvocidib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase multiple interactions ISO [alvocidib co-treated with Bortezomib co-treated with ABL1 protein] results in decreased phosphorylation of LYN protein; [alvocidib co-treated with Bortezomib co-treated with ABL1] results in decreased phosphorylation of CRKL protein; [alvocidib co-treated with Bortezomib] results in decreased expression of ABL1 protein CTD PMID:15039284 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases localization ISO alvocidib results in increased localization of AIFM1 protein CTD PMID:12734434 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [alvocidib co-treated with Bortezomib] results in decreased expression of AKT1 protein modified form CTD PMID:15039284 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO [Imatinib Mesylate co-treated with alvocidib] results in decreased expression of BAD protein CTD PMID:12231544 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bag1 BAG cochaperone 1 decreases expression ISO alvocidib results in decreased expression of BAG1 mRNA; alvocidib results in decreased expression of BAG1 protein; alvocidib results in decreased expression of BAG1 protein alternative form CTD PMID:10887097 PMID:15972445 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects localization
increases cleavage
increases expression
multiple interactions
ISO alvocidib affects the localization of BAX protein
alvocidib results in increased cleavage of BAX protein
alvocidib results in increased expression of BAX protein
[alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] affects the localization of BAX protein; [alvocidib co-treated with gemcitabine] results in increased expression of BAX protein; [alvocidib co-treated with TNFSF10 protein] results in increased localization of BAX protein; Epothilones promotes the reaction [alvocidib affects the localization of BAX protein]
CTD PMID:12517783 PMID:12589031 PMID:12734434 PMID:15634644 PMID:15770523 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
decreases response to substance
multiple interactions
increases expression
ISO alvocidib results in decreased expression of BCL2 mRNA; alvocidib results in decreased expression of BCL2 protein
BCL2 protein mutant form results in decreased susceptibility to alvocidib; BCL2 protein results in decreased susceptibility to alvocidib
[alvocidib co-treated with gemcitabine] results in decreased expression of BCL2 protein; BCL2 protein mutant form inhibits the reaction [alvocidib affects the localization of CYCS protein]; BCL2 protein mutant form inhibits the reaction [alvocidib results in increased activity of CASP3 protein]; BCL2 protein mutant form inhibits the reaction [alvocidib results in increased activity of CASP9 protein]; BCL2 protein mutant form inhibits the reaction [alvocidib results in increased cleavage of BID protein]; BCL2 protein mutant form inhibits the reaction [alvocidib results in increased cleavage of PARP1 protein]; BCL2 protein results in decreased susceptibility to [alvocidib co-treated with Epothilones]
alvocidib results in increased expression of BCL2
CTD PMID:10887097 PMID:10995888 PMID:12170773 PMID:12517783 PMID:12589031 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression
ISO [alvocidib co-treated with Bortezomib] results in decreased expression of BCL2L1 protein; [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in decreased expression of BCL2L1 protein; Epothilones promotes the reaction [alvocidib results in decreased expression of BCL2L1 mRNA]; Epothilones promotes the reaction [alvocidib results in decreased expression of BCL2L1 protein]
alvocidib results in decreased expression of BCL2L1; alvocidib results in decreased expression of BCL2L1 mRNA; alvocidib results in decreased expression of BCL2L1 protein
CTD PMID:12517783 PMID:15039284 PMID:15634644 PMID:16820931 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
increases cleavage
ISO [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased cleavage of BID protein; [alvocidib co-treated with TNFSF10 protein] results in decreased expression of BID protein; [Imatinib Mesylate co-treated with alvocidib] results in increased activity of BID protein; BCL2 protein mutant form inhibits the reaction [alvocidib results in increased cleavage of BID protein]; Boc-D-FMK inhibits the reaction [alvocidib results in increased cleavage of BID protein] CTD PMID:11464216 PMID:12170773 PMID:12231544 PMID:15634644 PMID:16951203 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression
multiple interactions
ISO alvocidib results in decreased expression of BIRC3 mRNA; alvocidib results in decreased expression of BIRC3 protein
Epothilones promotes the reaction [alvocidib results in decreased expression of BIRC3 mRNA]; Epothilones promotes the reaction [alvocidib results in decreased expression of BIRC3 protein]
CTD PMID:12517783 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression
ISO [alvocidib co-treated with 7-hydroxystaurosporine] results in decreased expression of BIRC5 protein; [alvocidib co-treated with PBOX-6] results in decreased expression of BIRC5 protein; alvocidib inhibits the reaction [Doxorubicin results in increased expression of and results in increased phosphorylation of BIRC5 protein]; alvocidib results in decreased phosphorylation of and results in decreased expression of BIRC5 protein
alvocidib results in decreased expression of BIRC5; alvocidib results in decreased expression of BIRC5 mRNA; alvocidib results in decreased expression of BIRC5 protein
CTD PMID:12517783 PMID:12517802 PMID:16012789 PMID:16820931 PMID:20206141 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO alvocidib results in increased expression of BTG2 mRNA CTD PMID:21382384 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Casp3 caspase 3 affects cleavage
multiple interactions
increases cleavage
increases activity
ISO
EXP
alvocidib affects the cleavage of CASP3 protein
alvocidib inhibits the reaction [Colchicine results in increased activity of CASP3 protein]
alvocidib results in increased cleavage of CASP3 protein
alvocidib results in increased activity of CASP3 protein
[alvocidib co-treated with 7-hydroxystaurosporine] results in increased activity of CASP3 protein; [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased cleavage of CASP3 protein; [alvocidib co-treated with gemcitabine] results in increased cleavage of CASP3 protein; [Imatinib Mesylate co-treated with alvocidib] results in increased activity of CASP3 protein; [irinotecan co-treated with alvocidib] results in increased activity of CASP3 protein; alvocidib affects the cleavage of and results in increased activity of CASP3 protein; alvocidib promotes the reaction [Paclitaxel results in increased activity of CASP3 protein]; alvocidib promotes the reaction [romidepsin results in increased activity of CASP3 protein]; alvocidib results in increased cleavage of and results in increased activity of CASP3 protein; BCL2 protein mutant form inhibits the reaction [alvocidib results in increased activity of CASP3 protein]; Boc-D-FMK inhibits the reaction [alvocidib results in increased cleavage of and results in increased activity of CASP3 protein]
CTD PMID:9808574 PMID:10430095 PMID:10896673 PMID:11482875 PMID:11751522 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions
increases cleavage
ISO [alvocidib co-treated with 7-hydroxystaurosporine] results in increased cleavage of CASP8 protein; [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased cleavage of CASP8 protein; [alvocidib co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein; [Imatinib Mesylate co-treated with alvocidib] results in increased activity of CASP8 protein
alvocidib results in increased cleavage of CASP8 protein
CTD PMID:10896673 PMID:12231544 PMID:12589031 PMID:15634644 PMID:16012789 More... NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 affects cleavage
increases activity
multiple interactions
ISO alvocidib affects the cleavage of CASP9 protein
alvocidib results in increased activity of CASP9 protein
[alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased cleavage of CASP9 protein; BCL2 protein mutant form inhibits the reaction [alvocidib results in increased activity of CASP9 protein]
CTD PMID:10896673 PMID:12170773 PMID:15634644 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cbr3 carbonyl reductase 3 decreases expression ISO alvocidib results in decreased expression of CBR3 mRNA CTD PMID:21382384 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO alvocidib results in decreased expression of and results in decreased activity of CCNA2 protein CTD PMID:16731754 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 multiple interactions
decreases expression
ISO [alvocidib co-treated with PBOX-6] results in decreased expression of CCNB1 protein; alvocidib inhibits the reaction [Paclitaxel results in increased expression of CCNB1 protein]; alvocidib results in decreased expression of and results in decreased activity of CCNB1 protein
alvocidib results in decreased expression of CCNB1 protein
CTD PMID:10430095 PMID:12517783 PMID:15014036 PMID:16731754 PMID:20206141 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
decreases activity
ISO [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in decreased expression of CCND1 protein
alvocidib results in decreased expression of CCND1 protein
alvocidib results in decreased activity of CCND1 protein
CTD PMID:9802881 PMID:9829756 PMID:10441105 PMID:12517783 PMID:12589031 More... NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO alvocidib results in decreased expression of CCNE1 protein CTD PMID:15014036 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
decreases expression
decreases activity
ISO [alvocidib co-treated with PBOX-6] results in decreased activity of CDK1 protein
alvocidib results in decreased expression of CDK1 protein modified form
alvocidib results in decreased activity of CDK1 protein
CTD PMID:9427698 PMID:9802881 PMID:12517783 PMID:16905211 PMID:20206141 More... NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression
decreases activity
multiple interactions
ISO alvocidib results in decreased expression of CDK2 protein modified form
alvocidib results in decreased activity of CDK2 protein
alvocidib binds to and results in decreased activity of CDK2 protein; alvocidib inhibits the reaction [Paclitaxel results in increased activity of CDK2 protein]
CTD PMID:9802881 PMID:10430095 PMID:12517783 PMID:16905211 PMID:24102143 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases activity
multiple interactions
decreases expression
ISO alvocidib results in decreased activity of CDK4 protein
alvocidib binds to and results in decreased activity of CDK4 protein
alvocidib results in decreased expression of CDK4 protein
CTD PMID:12517783 PMID:12734434 PMID:24102143 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk5 cyclin-dependent kinase 5 multiple interactions EXP alvocidib inhibits the reaction [Colchicine results in increased expression of CDK5 protein] CTD PMID:12941380 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Cdk9 cyclin-dependent kinase 9 multiple interactions ISO alvocidib binds to and results in decreased activity of CDK9 protein CTD PMID:24102143 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
decreases expression
increases cleavage
increases expression
affects expression
ISO [alvocidib co-treated with gemcitabine] results in increased expression of CDKN1A protein; alvocidib inhibits the reaction [romidepsin results in increased expression of CDKN1A promoter]; alvocidib inhibits the reaction [romidepsin results in increased expression of CDKN1A protein]; Phorbol 12,13-Dibutyrate inhibits the reaction [alvocidib inhibits the reaction [romidepsin results in increased expression of CDKN1A protein]]
alvocidib results in decreased expression of CDKN1A protein
alvocidib results in increased cleavage of CDKN1A protein
alvocidib results in increased expression of CDKN1A protein
alvocidib affects the expression of CDKN1A protein
CTD PMID:10537362 PMID:12734434 PMID:15014036 PMID:15180955 PMID:15770523 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases cleavage
increases expression
ISO alvocidib results in increased cleavage of CDKN1B protein
[alvocidib results in increased expression of TP53 protein] which results in increased expression of CDKN1B protein; alvocidib results in increased expression of CDKN1B protein
CTD PMID:10537362 PMID:12589031 PMID:15180955 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator affects expression
multiple interactions
decreases expression
ISO alvocidib affects the expression of CFLAR mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [alvocidib results in decreased expression of CFLAR protein]
alvocidib results in decreased expression of CFLAR; alvocidib results in decreased expression of CFLAR protein
CTD PMID:16820931 PMID:16951203 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein multiple interactions ISO [alvocidib co-treated with Bortezomib co-treated with ABL1] results in decreased phosphorylation of CRKL protein CTD PMID:15039284 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238
JBrowse link
G Cycs cytochrome c, somatic affects localization
multiple interactions
ISO alvocidib affects the localization of CYCS protein
[alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] affects the localization of CYCS protein; BCL2 protein mutant form inhibits the reaction [alvocidib affects the localization of CYCS protein]
CTD PMID:12170773 PMID:12517783 PMID:15634644 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein affects localization
multiple interactions
ISO alvocidib affects the localization of DIABLO protein
[alvocidib co-treated with Bortezomib] results in increased secretion of DIABLO protein; [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] affects the localization of DIABLO protein; [Imatinib Mesylate co-treated with alvocidib] results in increased secretion of DIABLO protein
CTD PMID:12231544 PMID:12517783 PMID:15039284 PMID:15634644 NCBI chr12:33,055,784...33,070,400
Ensembl chr12:33,055,263...33,070,387
JBrowse link
G E2f1 E2F transcription factor 1 increases expression
increases response to substance
decreases expression
ISO alvocidib results in increased expression of E2F1 protein
E2F1 results in increased susceptibility to alvocidib
alvocidib results in decreased expression of E2F1 mRNA
CTD PMID:12533675 PMID:21239698 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G H2ax H2A.X variant histone affects expression ISO alvocidib affects the expression of H2AX protein CTD PMID:15078984 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hmga1 high mobility group AT-hook 1 decreases expression ISO alvocidib results in decreased expression of HMGA1 mRNA CTD PMID:21239698 NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752
JBrowse link
G Htra2 HtrA serine peptidase 2 affects localization ISO alvocidib affects the localization of HTRA2 protein CTD PMID:12517783 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to IFIT1 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to ISG15 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to MX1 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [POLR2A protein binds to ISG15 gene]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [POLR2A protein binds to ISG15 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [SUPT5H protein binds to IFIT1 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [SUPT5H protein binds to ISG15 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [SUPT5H protein binds to MX1 promoter]]; alvocidib inhibits the reaction [IFNB1 protein results in increased expression of ISG15 mRNA] CTD PMID:23589332 NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier multiple interactions ISO alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to ISG15 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [POLR2A protein binds to ISG15 gene]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [POLR2A protein binds to ISG15 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [SUPT5H protein binds to ISG15 promoter]]; alvocidib inhibits the reaction [IFNB1 protein results in increased expression of ISG15 mRNA] CTD PMID:23589332 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Imatinib Mesylate co-treated with alvocidib] results in increased activity of JUN protein CTD PMID:12231544 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression
decreases phosphorylation
ISO alvocidib results in decreased expression of KIT mRNA; alvocidib results in decreased expression of KIT promoter
alvocidib results in decreased phosphorylation of KIT protein
CTD PMID:16740725 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase multiple interactions ISO [alvocidib co-treated with Bortezomib co-treated with ABL1 protein] results in decreased phosphorylation of LYN protein CTD PMID:15039284 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions ISO alvocidib promotes the reaction [Bortezomib results in increased phosphorylation of and results in increased activity of MAP2K4 protein] CTD PMID:15039284 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO alvocidib inhibits the reaction [Bortezomib results in increased expression of MAPK1 protein modified form]; alvocidib results in decreased activity of and results in decreased phosphorylation of MAPK1 protein CTD PMID:15014036 PMID:15039284 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased phosphorylation of and results in increased activity of MAPK14 protein CTD PMID:15634644 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO alvocidib inhibits the reaction [Bortezomib results in increased expression of MAPK3 protein modified form]; alvocidib results in decreased activity of and results in decreased phosphorylation of MAPK3 protein CTD PMID:15014036 PMID:15039284 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased phosphorylation of and results in increased activity of MAPK8 protein; alvocidib promotes the reaction [Bortezomib results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:15039284 PMID:15634644 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member affects expression
decreases response to substance
decreases expression
multiple interactions
ISO alvocidib affects the expression of MCL1 mRNA; alvocidib affects the expression of MCL1 protein
MCL1 results in decreased susceptibility to alvocidib
alvocidib results in decreased expression of MCL1 mRNA; alvocidib results in decreased expression of MCL1 protein
[alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in decreased expression of MCL1 protein; [Imatinib Mesylate co-treated with alvocidib] results in decreased expression of MCL1 protein; Epothilones promotes the reaction [alvocidib results in decreased expression of MCL1 mRNA]; Epothilones promotes the reaction [alvocidib results in decreased expression of MCL1 protein]
CTD PMID:10887097 PMID:12231544 PMID:12429644 PMID:12517783 PMID:12533675 More... NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mdm2 MDM2 proto-oncogene decreases expression ISO alvocidib results in decreased expression of MDM2 mRNA; alvocidib results in decreased expression of MDM2 protein CTD PMID:12589031 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mx1 MX dynamin like GTPase 1 multiple interactions ISO alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to MX1 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [SUPT5H protein binds to MX1 promoter]] CTD PMID:23589332 NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507
JBrowse link
G Nelfa negative elongation factor complex member A multiple interactions ISO alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to IFIT1 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to ISG15 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [NELFA protein binds to MX1 promoter]] CTD PMID:23589332 NCBI chr14:76,808,920...76,832,998
Ensembl chr14:76,808,870...76,832,994
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression
multiple interactions
ISO alvocidib results in increased expression of NFKBIA protein modified form
alvocidib promotes the reaction [Bortezomib results in increased expression of NFKBIA protein modified form]; Bortezomib promotes the reaction [alvocidib results in increased expression of NFKBIA protein modified form]
CTD PMID:15039284 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO alvocidib inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO [alvocidib co-treated with 7-hydroxystaurosporine] results in increased cleavage of PARP1 protein; [alvocidib co-treated with Bortezomib] results in increased cleavage of PARP1 protein; [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased cleavage of PARP1 protein; [alvocidib co-treated with gemcitabine] results in increased cleavage of PARP1 protein; alvocidib promotes the reaction [Paclitaxel results in increased cleavage of PARP1 protein]; BCL2 protein mutant form inhibits the reaction [alvocidib results in increased cleavage of PARP1 protein] CTD PMID:10430095 PMID:12170773 PMID:12517783 PMID:15039284 PMID:15634644 More... NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pawr pro-apoptotic WT1 regulator multiple interactions EXP alvocidib inhibits the reaction [Colchicine results in increased expression of PAWR protein] CTD PMID:12941380 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
JBrowse link
G Pcna proliferating cell nuclear antigen decreases activity ISO alvocidib results in decreased activity of PCNA protein CTD PMID:10441105 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Perp p53 apoptosis effector related to PMP22 increases expression ISO alvocidib results in increased expression of PERP mRNA CTD PMID:21382384 NCBI chr 1:13,542,067...13,554,514
Ensembl chr 1:13,542,067...13,554,511
JBrowse link
G Polr2a RNA polymerase II subunit A decreases expression
decreases phosphorylation
multiple interactions
ISO alvocidib results in decreased expression of POLR2A mRNA
alvocidib results in decreased phosphorylation of POLR2A protein
alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [POLR2A protein binds to ISG15 gene]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [POLR2A protein binds to ISG15 promoter]]
Bortezomib promotes the reaction [alvocidib results in decreased phosphorylation of POLR2A protein]
CTD PMID:15039284 PMID:21239698 PMID:23589332 PMID:24102143 NCBI chr10:54,452,438...54,478,486
Ensembl chr10:54,452,441...54,478,455
JBrowse link
G Pygb glycogen phosphorylase B affects binding ISO PYGB protein binds to alvocidib CTD PMID:11368340 NCBI chr 3:139,611,724...139,658,521
Ensembl chr 3:139,611,749...139,663,553
JBrowse link
G Pygl glycogen phosphorylase L affects binding ISO PYGL protein binds to alvocidib CTD PMID:11368340 NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases activity
decreases response to substance
multiple interactions
decreases phosphorylation
decreases expression
ISO alvocidib results in decreased activity of RB1 protein modified form
RB1 results in decreased susceptibility to alvocidib
[docetaxel co-treated with alvocidib] results in decreased phosphorylation of and results in decreased expression of RB1 protein
alvocidib results in decreased phosphorylation of RB1 protein
alvocidib results in decreased expression of RB1 protein; alvocidib results in decreased expression of RB1 protein modified form
CTD PMID:9829756 PMID:10441105 PMID:15180955 PMID:15297405 PMID:16905211 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 decreases expression ISO alvocidib results in decreased expression of RBL1 protein CTD PMID:9829756 NCBI chr 3:145,806,160...145,869,434
Ensembl chr 3:145,807,095...145,869,330
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
decreases expression
ISO [alvocidib co-treated with Bortezomib] results in decreased phosphorylation of and results in decreased activity of STAT3 protein
alvocidib results in decreased expression of STAT3 mRNA
CTD PMID:15039284 PMID:21239698 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Supt5h SPT5 homolog, DSIF elongation factor subunit multiple interactions ISO alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [SUPT5H protein binds to IFIT1 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [SUPT5H protein binds to ISG15 promoter]]; alvocidib inhibits the reaction [IFNB1 protein promotes the reaction [SUPT5H protein binds to MX1 promoter]] CTD PMID:23589332 NCBI chr 1:83,586,713...83,616,971
Ensembl chr 1:83,586,718...83,616,892
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases activity ISO alvocidib analog results in decreased activity of TGFB1 protein CTD PMID:31652400 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO alvocidib inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:21204955 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO alvocidib results in increased expression of TNFRSF10A CTD PMID:16820931 NCBI chr15:44,839,818...44,867,582
Ensembl chr15:44,840,386...44,867,467
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions
increases response to substance
increases expression
ISO [alvocidib co-treated with TNFSF10 protein] results in decreased expression of BID protein; [alvocidib co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein; [alvocidib co-treated with TNFSF10 protein] results in increased localization of BAX protein
alvocidib results in increased susceptibility to TNFSF10
alvocidib results in increased expression of TNFSF10
CTD PMID:16820931 PMID:16951203 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tp53 tumor protein p53 decreases expression
multiple interactions
increases expression
ISO alvocidib results in decreased expression of TP53 protein
[docetaxel co-treated with alvocidib] results in increased expression of TP53 protein
[alvocidib results in increased expression of TP53 protein] which results in increased expression of CDKN1B protein; alvocidib results in increased expression of TP53 protein
CTD PMID:9808574 PMID:10537362 PMID:12589031 PMID:15180955 PMID:15297405 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO alvocidib results in decreased expression of VEGFA mRNA CTD PMID:21239698 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression
multiple interactions
ISO alvocidib results in decreased expression of XIAP mRNA; alvocidib results in decreased expression of XIAP protein
[irinotecan co-treated with alvocidib] results in increased cleavage of XIAP protein; Epothilones promotes the reaction [alvocidib results in decreased expression of XIAP mRNA]; Epothilones promotes the reaction [alvocidib results in decreased expression of XIAP protein]
CTD PMID:10887097 PMID:11751522 PMID:12517783 PMID:15385934 PMID:15972445 More... NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
duvoglustat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO 1-Deoxynojirimycin inhibits the reaction [Dietary Fats results in increased expression of ACACA mRNA] CTD PMID:25445511 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G App amyloid beta precursor protein decreases response to substance ISO 1-Deoxynojirimycin results in decreased susceptibility to APP protein CTD PMID:19028522 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Casp3 caspase 3 multiple interactions EXP 1-Deoxynojirimycin inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]; 1-Deoxynojirimycin inhibits the reaction [Tunicamycin results in increased activity of CASP3 protein] CTD PMID:19028522 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cd36 CD36 molecule multiple interactions ISO 1-Deoxynojirimycin inhibits the reaction [Dietary Fats results in increased expression of CD36 mRNA] CTD PMID:25445511 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO 1-Deoxynojirimycin inhibits the reaction [Dietary Fats results in increased expression of CEBPA mRNA] CTD PMID:25445511 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions EXP 1-Deoxynojirimycin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; 1-Deoxynojirimycin inhibits the reaction [Tunicamycin results in increased expression of DDIT3 protein] CTD PMID:19028522 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO 1-Deoxynojirimycin inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA] CTD PMID:25445511 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbp2 fructose-bisphosphatase 2 multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FBP2 protein] CTD PMID:25446853 NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of G6PC protein] CTD PMID:25446853 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Gck glucokinase multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK protein] CTD PMID:25446853 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO 1-Deoxynojirimycin inhibits the reaction [Dietary Fats results in increased expression of GPT protein] CTD PMID:25445511 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Insr insulin receptor multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of INSR protein] CTD PMID:25446853 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Lpl lipoprotein lipase multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of LPL mRNA] CTD PMID:25446853 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Pc pyruvate carboxylase multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PCX protein] CTD PMID:25446853 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PCK1 protein] CTD PMID:25446853 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] results in increased expression of PDHA1 mRNA CTD PMID:25446853 NCBI chr  X:34,700,481...34,714,309
Ensembl chr  X:34,700,409...34,714,311
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA] CTD PMID:25446853 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
JBrowse link
G Pfkp phosphofructokinase, platelet multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PFKP protein] CTD PMID:25446853 NCBI chr17:63,729,743...63,794,021
Ensembl chr17:63,729,780...63,794,018
JBrowse link
G Pklr pyruvate kinase L/R multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PKLR protein] CTD PMID:25446853 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
JBrowse link
G Ppargc1b PPARG coactivator 1 beta multiple interactions ISO [1-Deoxynojirimycin co-treated with Dietary Fats] results in increased expression of PPARGC1B mRNA CTD PMID:25445511 NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194
JBrowse link
haloperidol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases activity
decreases expression
ISO Haloperidol inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]
Haloperidol results in decreased activity of ABCB1 protein
Haloperidol results in decreased expression of ABCB1 mRNA
CTD PMID:15946544 PMID:16810505 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
decreases expression
ISO Haloperidol inhibits the reaction [ABCC1 protein results in decreased susceptibility to Doxorubicin]
Haloperidol results in decreased expression of ABCC1 mRNA
CTD PMID:15946544 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Haloperidol inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone] CTD PMID:18834354 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain decreases expression ISO Haloperidol results in decreased expression of ACADVL protein CTD PMID:34122009 NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 decreases expression ISO Haloperidol results in decreased expression of ACAT1 protein CTD PMID:34122009 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of ACSL3 protein CTD PMID:34122009 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Adam1a ADAM metallopeptidase domain 1a decreases expression EXP Haloperidol results in decreased expression of ADAM1A mRNA CTD PMID:16715494 NCBI chr12:35,017,433...35,020,300
Ensembl chr12:35,017,315...35,020,311
JBrowse link
G Adcy5 adenylate cyclase 5 affects response to substance
multiple interactions
ISO ADCY5 protein affects the susceptibility to Haloperidol
SCH 23390 inhibits the reaction [ADCY5 protein affects the susceptibility to Haloperidol]
CTD PMID:12223546 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974
JBrowse link
G Adcyap1r1 ADCYAP receptor type I affects expression ISO Haloperidol affects the expression of ADCYAP1R1 mRNA CTD PMID:27900577 NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700
JBrowse link
G Adora2a adenosine A2a receptor affects response to substance ISO ADORA2A protein affects the susceptibility to Haloperidol CTD PMID:11172060 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Adsl adenylosuccinate lyase multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of ADSL protein CTD PMID:34122009 NCBI chr 7:112,479,256...112,503,439
Ensembl chr 7:112,479,271...112,503,760
JBrowse link
G Agpat1 1-acylglycerol-3-phosphate O-acyltransferase 1 decreases expression ISO Haloperidol results in decreased expression of AGPAT1 mRNA CTD PMID:14647396 NCBI chr20:4,135,955...4,144,880
Ensembl chr20:4,135,957...4,145,278
JBrowse link
G Agps alkylglycerone phosphate synthase multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of AGPS protein CTD PMID:34122009 NCBI chr 3:60,747,323...60,845,831
Ensembl chr 3:60,747,323...60,845,830
JBrowse link
G Ak4 adenylate kinase 4 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of AK4 protein CTD PMID:34122009 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression EXP Haloperidol results in decreased expression of AKT1 mRNA CTD PMID:15860345 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt2 AKT serine/threonine kinase 2 increases expression EXP Haloperidol results in increased expression of AKT2 mRNA CTD PMID:15860345 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 decreases expression ISO Haloperidol results in decreased expression of ALDH18A1 protein CTD PMID:34122009 NCBI chr 1:239,375,657...239,407,967
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP Haloperidol results in increased expression of ALDOA mRNA CTD PMID:15860345 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C increases expression EXP Haloperidol results in increased expression of ALDOC mRNA CTD PMID:15860345 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
JBrowse link
G Ankhd1 ankyrin repeat and KH domain containing 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of ANKHD1 protein CTD PMID:34122009 NCBI chr18:28,161,882...28,260,917
Ensembl chr18:28,162,311...28,268,024
JBrowse link
G Ap2a2 adaptor related protein complex 2 subunit alpha 2 decreases expression EXP Haloperidol results in decreased expression of AP2A2 mRNA CTD PMID:15860345 NCBI chr 1:196,652,315...196,725,609
Ensembl chr 1:196,652,337...196,725,603
JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 affects expression EXP Haloperidol affects the expression of AP2B1 mRNA CTD PMID:15860345 NCBI chr10:68,099,397...68,205,023
Ensembl chr10:68,099,547...68,205,013
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 increases expression ISO Haloperidol results in increased expression of AP2M1 protein CTD PMID:34122009 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
JBrowse link
G Ap3b1 adaptor related protein complex 3 subunit beta 1 increases expression ISO Haloperidol results in increased expression of AP3B1 protein CTD PMID:34122009 NCBI chr 2:25,600,069...25,800,937
Ensembl chr 2:25,600,040...25,800,935
JBrowse link
G Apod apolipoprotein D increases expression ISO Haloperidol results in increased expression of APOD mRNA CTD PMID:14647396 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305
JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of APPL1 protein CTD PMID:34122009 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein increases expression
multiple interactions
EXP Haloperidol results in increased expression of ARC mRNA
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of ARC mRNA]
CTD PMID:18208916 PMID:19695244 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
JBrowse link
G Arf1 ADP-ribosylation factor 1 decreases expression EXP Haloperidol results in decreased expression of ARF1 mRNA CTD PMID:15860345 NCBI chr10:43,997,983...44,014,543
Ensembl chr10:43,997,986...44,014,434
JBrowse link
G Arf3 ADP-ribosylation factor 3 decreases expression EXP Haloperidol results in decreased expression of ARF3 mRNA CTD PMID:15860345 NCBI chr 7:129,886,082...129,912,022
Ensembl chr 7:129,886,082...129,912,002
JBrowse link
G Arl3 ADP ribosylation factor like GTPase 3 decreases expression EXP Haloperidol results in decreased expression of ARL3 mRNA CTD PMID:15860345 NCBI chr 1:245,400,659...245,446,673
Ensembl chr 1:245,400,550...245,446,820
JBrowse link
G Arl5a ADP-ribosylation factor like GTPase 5A decreases expression EXP Haloperidol results in decreased expression of ARL5A mRNA CTD PMID:15860345 NCBI chr 3:36,878,461...36,903,362
Ensembl chr 3:36,880,712...36,903,211
JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 increases expression ISO Haloperidol results in increased expression of ARPC4 mRNA CTD PMID:14647396 NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO Haloperidol results in decreased expression of ASNS mRNA CTD PMID:17175557 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Asph aspartate-beta-hydroxylase increases expression ISO Haloperidol results in increased expression of ASPH protein CTD PMID:34122009 NCBI chr 5:22,603,879...22,814,107
Ensembl chr 5:22,603,486...22,813,876
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 decreases expression EXP Haloperidol results in decreased expression of ATP1A1 mRNA CTD PMID:15860345 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 decreases expression EXP Haloperidol results in decreased expression of ATP1A3 mRNA CTD PMID:15860345 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 increases expression EXP Haloperidol results in increased expression of ATP1B1 mRNA CTD PMID:15860345 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 decreases expression EXP Haloperidol results in decreased expression of ATP1B2 mRNA CTD PMID:15860345 NCBI chr10:54,318,698...54,324,933
Ensembl chr10:54,318,701...54,324,933
JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 increases expression EXP Haloperidol results in increased expression of ATP1B3 mRNA CTD PMID:15860345 NCBI chr 8:96,910,265...96,941,592
Ensembl chr 8:96,910,309...96,941,598
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of ATP2A3 protein CTD PMID:34122009 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748
JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 decreases expression ISO Haloperidol results in decreased expression of ATP6V1B1 protein CTD PMID:34122009 NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475
JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 decreases expression ISO Haloperidol results in decreased expression of ATP6V1B2 mRNA CTD PMID:16465460 NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745
JBrowse link
G Axin2 axin 2 decreases expression EXP Haloperidol results in decreased expression of AXIN2 mRNA CTD PMID:16715494 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression
EXP Haloperidol results in decreased expression of BAX protein
Haloperidol results in increased expression of BAX mRNA; Haloperidol results in increased expression of BAX protein
CTD PMID:16462815 PMID:17069804 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 decreases expression ISO Haloperidol results in decreased expression of BCAT2 protein CTD PMID:34122009 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP Haloperidol results in increased expression of BCL2 protein CTD PMID:17069804 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression
increases expression
EXP EPO protein inhibits the reaction [Haloperidol results in decreased expression of BCL2L1 protein]
Haloperidol results in increased expression of BCL2L1 protein
CTD PMID:16462815 PMID:17805306 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
decreases expression
increases expression
EXP
ISO
BDNF protein inhibits the reaction [Haloperidol results in increased activity of CASP3 protein]; EPO protein inhibits the reaction [Haloperidol results in decreased expression of BDNF protein]; Haloperidol inhibits the reaction [Rotenone results in decreased expression of BDNF mRNA]
Haloperidol results in decreased expression of BDNF mRNA; Haloperidol results in decreased expression of BDNF protein
Haloperidol inhibits the reaction [Cocaine results in decreased expression of BDNF protein]
Haloperidol results in increased expression of BDNF protein
Haloperidol results in increased expression of BDNF mRNA
CTD PMID:11488957 PMID:12393228 PMID:12478621 PMID:15168214 PMID:17442543 More... NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bet1l Bet1 golgi vesicular membrane trafficking protein-like affects expression EXP Haloperidol affects the expression of BET1L mRNA CTD PMID:15860345 NCBI chr 1:195,930,165...195,935,072
Ensembl chr 1:195,931,411...195,935,040
JBrowse link
G Bop1 BOP1 ribosomal biogenesis factor multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of BOP1 protein CTD PMID:34122009 NCBI chr 7:108,172,062...108,195,875
Ensembl chr 7:108,172,066...108,195,931
JBrowse link
G Bptf bromodomain PHD finger transcription factor decreases expression ISO Haloperidol results in decreased expression of BPTF mRNA CTD PMID:14647396 NCBI chr10:91,980,279...92,082,731
Ensembl chr10:91,982,758...92,082,769
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A decreases expression EXP
ISO
Haloperidol results in decreased expression of CACNA1A mRNA CTD PMID:14647396 PMID:16715494 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225
JBrowse link
G Calca calcitonin-related polypeptide alpha affects activity EXP Haloperidol affects the activity of CALCA protein CTD PMID:10075105 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Calm2 calmodulin 2 increases expression EXP Haloperidol results in increased expression of CALM2 mRNA CTD PMID:19289156 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions
decreases expression
increases expression
EXP Haloperidol results in decreased expression of and results in decreased phosphorylation of CAMK2A protein
Haloperidol results in decreased expression of CAMK2A protein
Haloperidol results in increased expression of CAMK2A mRNA
CTD PMID:15860345 PMID:18061412 PMID:19289156 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression EXP Haloperidol results in decreased expression of CAMK2B mRNA CTD PMID:15860345 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta decreases expression EXP Haloperidol results in decreased expression of CAMK2D mRNA CTD PMID:15860345 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV decreases expression
increases expression
EXP Haloperidol results in decreased expression of CAMK4 protein
Haloperidol results in increased expression of CAMK4 mRNA
CTD PMID:15860345 PMID:19289156 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487
JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1 decreases expression EXP Haloperidol results in decreased expression of CAMKK1 protein CTD PMID:19289156 NCBI chr10:57,637,335...57,660,498
Ensembl chr10:57,637,391...57,660,498
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 decreases expression EXP Haloperidol results in decreased expression of CAMKK2 protein CTD PMID:19289156 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279
JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of CAP1 protein CTD PMID:34122009 NCBI chr 5:135,142,108...135,168,885
Ensembl chr 5:135,142,112...135,168,769
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression
EXP BDNF protein inhibits the reaction [Haloperidol results in increased activity of CASP3 protein]; EPO protein inhibits the reaction [Haloperidol results in increased expression of CASP3 protein] CTD PMID:15168214 PMID:17805306 PMID:18590723 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions
decreases activity
decreases expression
EXP
ISO
Carvedilol inhibits the reaction [Haloperidol results in decreased expression of CAT protein]; Haloperidol results in decreased activity of and results in decreased expression of CAT protein; Zolpidem inhibits the reaction [Haloperidol results in decreased activity of CAT]
Cannabidiol inhibits the reaction [Haloperidol results in decreased activity of CAT protein]
CTD PMID:12010767 PMID:12482469 PMID:16564057 PMID:17513028 PMID:30217539 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cbx5 chromobox 5 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of CBX5 protein CTD PMID:34122009 NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022
JBrowse link
G Ccdc121rt coiled-coil domain containing 121, retrotransposed increases expression ISO Haloperidol results in increased expression of CCDC121 protein CTD PMID:34122009 NCBI chr13:93,253,752...93,255,406
Ensembl chr13:93,254,387...93,255,358
JBrowse link
G Cck cholecystokinin increases expression EXP Haloperidol results in increased expression of CCK mRNA CTD PMID:10974607 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP Haloperidol results in decreased expression of CCND1 mRNA CTD PMID:15860345 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd3 cyclin D3 increases expression EXP Haloperidol results in increased expression of CCND3 mRNA CTD PMID:15860345 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccnl1 cyclin L1 increases expression EXP Haloperidol results in increased expression of CCNL1 mRNA CTD PMID:15860345 NCBI chr 2:150,184,865...150,199,524
Ensembl chr 2:150,184,798...150,197,368
JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of CCT8 protein CTD PMID:34122009 NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079
JBrowse link
G Cdc42 cell division cycle 42 increases expression EXP Haloperidol results in increased expression of CDC42 mRNA CTD PMID:15860345 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression EXP Haloperidol results in increased expression of CDK4 mRNA CTD PMID:15860345 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk5 cyclin-dependent kinase 5 increases expression EXP Haloperidol results in increased expression of CDK5 mRNA CTD PMID:15860345 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Cfap161 cilia and flagella associated protein 161 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of CFAP161 protein CTD PMID:34122009 NCBI chr 1:137,743,783...137,768,685
Ensembl chr 1:137,743,784...137,768,730
JBrowse link
G Cfdp1 craniofacial development protein 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of CFDP1 protein CTD PMID:34122009 NCBI chr19:39,718,313...39,823,819
Ensembl chr19:39,718,347...39,823,824
JBrowse link
G Cfl1 cofilin 1 increases expression ISO Haloperidol results in increased expression of CFL1 protein CTD PMID:34122009 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Chl1 cell adhesion molecule L1-like decreases expression ISO Haloperidol results in decreased expression of CHL1 mRNA CTD PMID:14647396 NCBI chr 4:136,291,504...136,505,830
Ensembl chr 4:136,291,463...136,503,265
JBrowse link
G Chn1 chimerin 1 decreases expression ISO Haloperidol results in decreased expression of CHN1 mRNA CTD PMID:14647396 NCBI chr 3:58,509,822...58,676,774
Ensembl chr 3:58,510,536...58,676,490
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 increases expression ISO Haloperidol results in increased expression of CHORDC1 protein CTD PMID:34122009 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 affects response to substance ISO CHRM4 affects the susceptibility to Haloperidol CTD PMID:21269601 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159
JBrowse link
G Cldn11 claudin 11 decreases expression ISO Haloperidol results in decreased expression of CLDN11 mRNA CTD PMID:17177202 NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050
JBrowse link
G Clta clathrin, light chain A affects expression EXP Haloperidol affects the expression of CLTA mRNA CTD PMID:15860345 NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472
JBrowse link
G Cltb clathrin, light chain B decreases expression EXP Haloperidol results in decreased expression of CLTB mRNA CTD PMID:15860345 NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169
JBrowse link
G Cmya5 cardiomyopathy associated 5 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of CMYA5 protein CTD PMID:34122009 NCBI chr 2:24,279,520...24,378,253
Ensembl chr 2:24,279,528...24,378,364
JBrowse link
G Cnot3 CCR4-NOT transcription complex, subunit 3 decreases expression ISO Haloperidol results in decreased expression of CNOT3 protein CTD PMID:34122009 NCBI chr 1:65,555,924...65,572,167
Ensembl chr 1:65,555,924...65,572,167
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases expression ISO Haloperidol results in decreased expression of CNP mRNA CTD PMID:17177202 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
increases methylation
ISO
EXP
CNR1 protein affects the reaction [[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]]; CNR1 protein affects the reaction [[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]]
Haloperidol inhibits the reaction [Methylazoxymethanol Acetate results in decreased methylation of CNR1 promoter]
Haloperidol results in increased methylation of CNR1 promoter
CTD PMID:28017790 PMID:30496751 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Coil coilin increases expression EXP Haloperidol results in increased expression of COIL mRNA CTD PMID:16715494 NCBI chr10:73,789,077...73,810,378
Ensembl chr10:73,789,488...73,810,393
JBrowse link
G Cops3 COP9 signalosome subunit 3 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of COPS3 protein CTD PMID:34122009 NCBI chr10:44,618,115...44,652,807
Ensembl chr10:44,618,115...44,641,597
JBrowse link
G Cops4 COP9 signalosome subunit 4 decreases expression ISO Haloperidol results in decreased expression of COPS4 protein CTD PMID:34122009 NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,078,576...9,108,887
JBrowse link
G Cpn1 carboxypeptidase N subunit 1 increases expression EXP Haloperidol results in increased expression of CPN1 mRNA CTD PMID:16715494 NCBI chr 1:242,844,575...242,873,465
Ensembl chr 1:242,844,212...242,873,465
JBrowse link
G Cpne3 copine 3 decreases expression ISO Haloperidol results in decreased expression of CPNE3 protein CTD PMID:34122009 NCBI chr 5:33,014,658...33,064,004
Ensembl chr 5:33,016,307...33,063,934
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases phosphorylation
increases activity
ISO
EXP
Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of CREB1 protein]
Haloperidol results in increased activity of CREB1 protein modified form
Amphetamine affects the reaction [Haloperidol results in increased activity of CREB1 protein modified form]
CTD PMID:12125044 PMID:12871586 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crh corticotropin releasing hormone decreases expression ISO Haloperidol results in decreased expression of CRH mRNA CTD PMID:16205782 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Crhbp corticotropin releasing hormone binding protein decreases expression EXP Haloperidol results in decreased expression of CRHBP mRNA CTD PMID:16715494 NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710
JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression ISO Haloperidol results in decreased expression of CRY1 mRNA CTD PMID:27746588 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 decreases expression EXP Haloperidol results in decreased expression of CSNK2A1 mRNA CTD PMID:16715494 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696
JBrowse link
G Cst3 cystatin C increases expression ISO Haloperidol results in increased expression of CST3 mRNA CTD PMID:14647396 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
JBrowse link
G Ctnna1 catenin alpha 1 decreases expression ISO Haloperidol results in decreased expression of CTNNA1 protein CTD PMID:34122009 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression
multiple interactions
increases expression
ISO
EXP
Haloperidol results in decreased expression of CTNNB1 mRNA
DRD2 protein affects the reaction [Haloperidol results in increased expression of CTNNB1 protein]
CTD PMID:16144542 PMID:18797397 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctrl chymotrypsin-like increases expression EXP Haloperidol results in increased expression of CTRL mRNA CTD PMID:16715494 NCBI chr19:33,827,279...33,829,129
Ensembl chr19:33,827,229...33,833,626
JBrowse link
G Ctsk cathepsin K increases expression EXP Haloperidol results in increased expression of CTSK mRNA CTD PMID:16715494 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
JBrowse link
G Cyb5r1 cytochrome b5 reductase 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of CYB5R1 protein CTD PMID:34122009 NCBI chr13:45,849,017...45,855,458
Ensembl chr13:45,849,091...45,855,458
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects response to substance ISO CYP2D6 protein polymorphism affects the susceptibility to Haloperidol CTD PMID:15538130 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol; Fluoxetine inhibits the reaction [CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol]; Fluvoxamine inhibits the reaction [CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol]; nefazodone inhibits the reaction [CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol]; norfluoxetine inhibits the reaction [CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol]; Trazodone inhibits the reaction [CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol] CTD PMID:12584149 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol; Fluoxetine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; Fluvoxamine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; nefazodone inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; norfluoxetine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; Trazodone inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol] CTD PMID:12584149 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Dcaf6 DDB1 and CUL4 associated factor 6 decreases expression ISO Haloperidol results in decreased expression of DCAF6 mRNA CTD PMID:14647396 NCBI chr13:77,626,257...77,727,645
Ensembl chr13:77,626,307...77,727,512
JBrowse link
G Dclk1 doublecortin-like kinase 1 increases expression ISO
EXP
Haloperidol results in increased expression of DCLK1 mRNA CTD PMID:15860345 PMID:18797397 NCBI chr 2:139,417,234...139,710,956
Ensembl chr 2:139,417,163...139,710,956
JBrowse link
G Ddx27 DEAD-box helicase 27 increases expression ISO Haloperidol results in increased expression of DDX27 protein CTD PMID:34122009 NCBI chr 3:155,744,182...155,763,380
Ensembl chr 3:155,744,150...155,763,372
JBrowse link
G Ddx46 DEAD-box helicase 46 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of DDX46 protein CTD PMID:34122009 NCBI chr17:8,944,197...8,988,476
Ensembl chr17:8,944,454...8,988,439
JBrowse link
G Ddx5 DEAD-box helicase 5 decreases expression ISO Haloperidol results in decreased expression of DDX5 protein CTD PMID:34122009 NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283
JBrowse link
G Dennd10 DENN domain containing 10 increases expression EXP Haloperidol results in increased expression of DENND10 mRNA CTD PMID:16715494 NCBI chr 1:259,950,928...259,974,456
Ensembl chr 1:259,950,866...259,974,455
JBrowse link
G Depp1 DEPP1, autophagy regulator increases expression ISO Haloperidol results in increased expression of DEPP1 mRNA CTD PMID:17175557 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
JBrowse link
G Dgka diacylglycerol kinase, alpha decreases expression EXP Haloperidol results in decreased expression of DGKA mRNA CTD PMID:15860345 NCBI chr 7:1,148,734...1,175,324
Ensembl chr 7:1,148,735...1,175,110
JBrowse link
G Dhx36 DEAH-box helicase 36 decreases expression ISO Haloperidol results in decreased expression of DHX36 protein CTD PMID:34122009 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572
JBrowse link
G Dhx38 DEAH-box helicase 38 decreases expression ISO Haloperidol results in decreased expression of DHX38 protein CTD PMID:34122009 NCBI chr19:37,512,891...37,530,140
Ensembl chr19:37,512,891...37,530,140
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase decreases expression EXP Haloperidol results in decreased expression of DLAT mRNA CTD PMID:15860345 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 increases expression ISO Haloperidol results in increased expression of DLG2 protein CTD PMID:34122009 NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475
JBrowse link
G Dnah1 dynein, axonemal, heavy chain 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of DNAH1 protein CTD PMID:34122009 NCBI chr16:6,455,514...6,517,103
Ensembl chr16:6,456,002...6,518,350
JBrowse link
G Dnah3 dynein, axonemal, heavy chain 3 increases expression ISO Haloperidol results in increased expression of DNAH3 protein CTD PMID:34122009 NCBI chr 1:174,305,929...174,479,490
Ensembl chr 1:174,306,644...174,479,474
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of DNAJB1 protein CTD PMID:34122009 NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458
JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 multiple interactions
increases expression
ISO [Cuprizone co-treated with Haloperidol] results in increased expression of DNAJB11 protein
Haloperidol results in increased expression of DNAJB11 protein
CTD PMID:34122009 NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407
JBrowse link
G Dpf1 double PHD fingers 1 increases expression ISO Haloperidol results in increased expression of DPF1 mRNA CTD PMID:14647396 NCBI chr 1:84,602,212...84,615,954
Ensembl chr 1:84,602,336...84,615,950
JBrowse link
G Dr1 down-regulator of transcription 1 decreases expression ISO Haloperidol results in decreased expression of DR1 protein CTD PMID:34122009 NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638
JBrowse link
G Drd1 dopamine receptor D1 affects binding
affects activity
decreases expression
increases expression
ISO
EXP
Haloperidol binds to DRD1 protein
Haloperidol affects the activity of DRD1 protein
Haloperidol results in decreased expression of DRD1 mRNA
Haloperidol results in increased expression of DRD1 protein
CTD PMID:8750706 PMID:8794996 PMID:12887421 PMID:16983399 PMID:23611293 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd2 dopamine receptor D2 affects binding
increases expression
multiple interactions
affects response to substance
affects activity
ISO
EXP
DRD2 protein binds to Haloperidol; DRD2 protein binds to Haloperidol analog; Haloperidol binds to DRD2 protein
Haloperidol results in increased expression of DRD2 mRNA; Haloperidol results in increased expression of DRD2 protein
Thioctic Acid inhibits the reaction [Haloperidol results in increased expression of DRD2 mRNA]; Thioctic Acid inhibits the reaction [Haloperidol results in increased expression of DRD2 protein]
DRD2 affects the susceptibility to Haloperidol; DRD2 protein affects the susceptibility to Haloperidol
[Haloperidol binds to and results in decreased activity of DRD2 protein] which results in decreased susceptibility to Ethanol; [Haloperidol results in increased expression of DRD2 protein] which results in decreased susceptibility to Pentobarbital; Haloperidol binds to and results in decreased activity of DRD2 protein
Haloperidol binds to DRD2; Haloperidol binds to DRD2 protein; Haloperidol binds to DRD2 protein alternative form
Haloperidol results in increased expression of DRD2; Haloperidol results in increased expression of DRD2 mRNA; Haloperidol results in increased expression of DRD2 protein
[Haloperidol binds to and results in decreased activity of DRD2 protein] which results in increased expression of PPP3CA protein; cyclo(leucylglycine) inhibits the reaction [Haloperidol results in increased expression of DRD2 protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of CTNNB1 protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of DVL3 protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3A protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3B protein]; felbamate inhibits the reaction [Haloperidol affects the activity of DRD2 protein]; Haloperidol binds to and results in decreased activity of DRD2 protein; Haloperidol inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] which results in increased uptake of Dopamine]; Haloperidol inhibits the reaction [iodosulpride binds to DRD2 protein]; Haloperidol inhibits the reaction [Spiperone binds to DRD2 protein]; Haloperidol promotes the reaction [Dopamine binds to DRD2 protein]; zinc chloride inhibits the reaction [Haloperidol binds to DRD2 protein]
CTD PMID:1351265 PMID:1361536 PMID:1380082 PMID:2945998 PMID:7845605 More... NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd3 dopamine receptor D3 affects binding
multiple interactions
ISO
EXP
DRD3 protein binds to Haloperidol analog
Haloperidol affects the reaction [Methylazoxymethanol Acetate results in increased expression of DRD3 mRNA]
CTD PMID:14552778 PMID:32360362 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Drd4 dopamine receptor D4 affects activity
affects binding
ISO
EXP
Haloperidol affects the activity of DRD4 protein
Haloperidol binds to Drd4 protein
CTD
RGD
PMID:23611293 PMID:8078498 RGD:7248459 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Drp2 dystrophin related protein 2 increases expression EXP Haloperidol results in increased expression of DRP2 mRNA alternative form CTD PMID:16715494 NCBI chr  X:97,607,577...97,658,115
Ensembl chr  X:97,607,719...97,655,684
JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 increases response to substance
affects response to substance
ISO DTNBP1 gene polymorphism results in increased susceptibility to Haloperidol
DTNBP1 protein affects the susceptibility to Haloperidol
CTD PMID:19369910 NCBI chr17:19,685,218...19,776,668
Ensembl chr17:19,685,215...19,776,661
JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression EXP Haloperidol results in decreased expression of DUSP1 mRNA CTD PMID:15860345 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression EXP Haloperidol results in decreased expression of DUSP6 mRNA CTD PMID:15860345 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Dvl3 dishevelled segment polarity protein 3 multiple interactions
increases expression
EXP DRD2 protein affects the reaction [Haloperidol results in increased expression of DVL3 protein] CTD PMID:16144542 NCBI chr11:80,365,446...80,382,641
Ensembl chr11:80,366,117...80,382,462
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of EEF1G protein CTD PMID:34122009 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382
JBrowse link
G Egr1 early growth response 1 affects expression
increases expression
multiple interactions
EXP
ISO
Haloperidol affects the expression of EGR1 protein
Haloperidol results in increased expression of EGR1 mRNA; Haloperidol results in increased expression of EGR1 protein
Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]; OPRM1 protein inhibits the reaction [Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]]
CTD PMID:12243769 PMID:16452686 PMID:17028028 PMID:17913375 PMID:18208916 More... NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr2 early growth response 2 affects expression
decreases expression
increases expression
ISO
EXP
Haloperidol affects the expression of EGR2 mRNA
Haloperidol results in decreased expression of EGR2 protein
Haloperidol results in increased expression of EGR2 mRNA
CTD PMID:17028028 PMID:18208916 PMID:19401217 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon increases expression ISO Haloperidol results in increased expression of EIF2B5 protein CTD PMID:34122009 NCBI chr11:80,394,433...80,404,468
Ensembl chr11:80,394,433...80,404,419
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of EIF5A protein CTD PMID:34122009 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
JBrowse link
G Elk1 ETS transcription factor ELK1 increases phosphorylation
multiple interactions
ISO
EXP
Haloperidol results in increased phosphorylation of ELK1 protein
SL 327 inhibits the reaction [Haloperidol results in increased phosphorylation of ELK1 protein]
Nifedipine affects the reaction [Haloperidol results in increased phosphorylation of ELK1 protein]
CTD PMID:12871586 PMID:17913375 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713
JBrowse link
G Eno1 enolase 1 increases expression EXP Haloperidol results in increased expression of ENO1 mRNA CTD PMID:15860345 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Epo erythropoietin multiple interactions EXP EPO protein inhibits the reaction [Haloperidol results in decreased expression of BCL2L1 protein]; EPO protein inhibits the reaction [Haloperidol results in decreased expression of BDNF protein]; EPO protein inhibits the reaction [Haloperidol results in increased expression of CASP3 protein] CTD PMID:17805306 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 decreases expression ISO Haloperidol results in decreased expression of ERAP1 protein CTD PMID:34122009 NCBI chr 2:3,931,817...3,970,735
Ensembl chr 2:3,931,904...3,972,447
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions EXP Haloperidol results in increased expression of and results in increased phosphorylation of ERBB2 protein CTD PMID:26961615 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 increases expression
multiple interactions
EXP Haloperidol results in increased expression of ERBB4 protein
Haloperidol results in increased expression of and results in increased phosphorylation of ERBB4 protein
CTD PMID:18184445 PMID:26961615 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
JBrowse link
G Ergic1 endoplasmic reticulum-golgi intermediate compartment 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of ERGIC1 protein CTD PMID:34122009 NCBI chr10:16,531,192...16,627,183
Ensembl chr10:16,531,194...16,626,957
JBrowse link
G Ezr ezrin decreases expression ISO Haloperidol results in decreased expression of EZR protein CTD PMID:34122009 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G Fabp3 fatty acid binding protein 3 affects response to substance
increases expression
ISO FABP3 affects the susceptibility to Haloperidol
Haloperidol results in increased expression of FABP3 protein
CTD PMID:20181611 PMID:34122009 NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718
JBrowse link
G Fasn fatty acid synthase increases expression ISO Haloperidol results in increased expression of FASN mRNA CTD PMID:16027736 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression ISO Haloperidol results in decreased expression of FLT1 protein CTD PMID:34122009 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Fndc4 fibronectin type III domain containing 4 increases expression ISO Haloperidol results in increased expression of FNDC4 mRNA CTD PMID:17175557 NCBI chr 6:25,077,155...25,080,812
Ensembl chr 6:25,077,349...25,080,675
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression
increases expression
ISO
EXP
8-Hydroxy-2-(di-n-propylamino)tetralin affects the reaction [Haloperidol results in increased expression of FOS protein]; Dizocilpine Maleate inhibits the reaction [Haloperidol results in increased expression of FOS protein]; ifenprodil inhibits the reaction [Haloperidol results in increased expression of FOS protein]; tandospirone inhibits the reaction [Haloperidol results in increased expression of FOS protein]; traxoprodil mesylate inhibits the reaction [Haloperidol results in increased expression of FOS protein]; WAY 100135 inhibits the reaction [tandospirone inhibits the reaction [Haloperidol results in increased expression of FOS protein]]
8-(3-chlorostyryl)caffeine inhibits the reaction [Haloperidol results in increased expression of FOS mRNA]; 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of FOS mRNA]; Clozapine affects the reaction [Haloperidol results in increased expression of FOS protein]; Dronabinol promotes the reaction [Haloperidol results in increased expression of FOS protein]; Nifedipine affects the reaction [Haloperidol results in increased expression of FOS protein]; Nimodipine affects the reaction [Haloperidol results in increased expression of FOS protein]; Propranolol inhibits the reaction [Haloperidol results in increased expression of FOS protein]; Scopolamine inhibits the reaction [Haloperidol results in increased expression of FOS protein]; Theophylline inhibits the reaction [Haloperidol results in increased expression of FOS mRNA]
Haloperidol results in decreased expression of FOS mRNA; Haloperidol results in decreased expression of FOS protein
Haloperidol results in increased expression of FOS mRNA; Haloperidol results in increased expression of FOS protein
CTD PMID:1393566 PMID:9571656 PMID:9748542 PMID:10199625 PMID:10435392 More... NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO
EXP
Haloperidol results in increased expression of FOSB protein alternative form
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of FOSB mRNA]
Haloperidol results in increased expression of FOSB modified form; Haloperidol results in increased expression of FOSB mRNA; Haloperidol results in increased expression of FOSB protein
CTD PMID:8714707 PMID:11180499 PMID:12243769 PMID:15579174 PMID:19695244 More... NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions
increases expression
EXP Amphetamine affects the reaction [Haloperidol results in increased expression of FOSL1 protein]
Haloperidol results in increased expression of FOSL1 mRNA; Haloperidol results in increased expression of FOSL1 protein
CTD PMID:12125044 PMID:18208916 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression EXP Haloperidol results in increased expression of FOSL2 mRNA CTD PMID:12243769 NCBI chr 6:24,297,898...24,319,157
Ensembl chr 6:24,300,956...24,320,034
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions
affects response to substance
increases phosphorylation
ISO FYN gene mutant form inhibits the reaction [Haloperidol results in increased phosphorylation of GRIN2B protein]
FYN protein affects the susceptibility to Haloperidol
Haloperidol results in increased phosphorylation of FYN protein
CTD PMID:16407246 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 decreases expression ISO Haloperidol results in decreased expression of GABRA1 mRNA CTD PMID:18797397 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 increases expression EXP Haloperidol results in increased expression of GABRB3 mRNA CTD PMID:18923069 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions
decreases expression
increases expression
EXP [Haloperidol co-treated with Fluvoxamine] affects the expression of GAD1 protein
Haloperidol results in decreased expression of GAD1 mRNA; Haloperidol results in decreased expression of GAD1 protein
Haloperidol results in increased expression of GAD1 mRNA
CTD PMID:12887421 PMID:14519413 PMID:15061247 PMID:15967061 PMID:18923069 More... NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
JBrowse link
G Gad2 glutamate decarboxylase 2 decreases expression
increases expression
EXP Haloperidol results in decreased expression of GAD2 mRNA; Haloperidol results in decreased expression of GAD2 protein
Haloperidol results in increased expression of GAD2 mRNA
CTD PMID:18923069 PMID:19359144 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155
JBrowse link
G Galnt2 polypeptide N-acetylgalactosaminyltransferase 2 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of GALNT2 protein CTD PMID:34122009 NCBI chr19:52,213,226...52,324,816
Ensembl chr19:52,213,351...52,324,813
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression EXP Haloperidol results in increased expression of GAPDH mRNA CTD PMID:15860345 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gda guanine deaminase multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of GDA protein CTD PMID:34122009 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO Haloperidol results in increased expression of GDPD3 mRNA CTD PMID:17175557 NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression ISO Haloperidol results in decreased expression of GFAP protein CTD PMID:34122009 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gimap5 GTPase, IMAP family member 5 decreases expression EXP Haloperidol results in decreased expression of GIMAP5 mRNA CTD PMID:16715494 NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP Haloperidol results in decreased expression of GJA1 protein CTD PMID:18585900 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Glo1 glyoxalase 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of GLO1 protein CTD PMID:34122009 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Glul glutamate-ammonia ligase decreases expression EXP Haloperidol results in decreased expression of GLUL mRNA CTD PMID:15860345 NCBI chr13:65,969,064...66,035,121
Ensembl chr13:66,025,630...66,035,108
JBrowse link
G Gna12 G protein subunit alpha 12 decreases expression EXP Haloperidol results in decreased expression of GNA12 mRNA CTD PMID:15860345 NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255
JBrowse link
G Gnai1 G protein subunit alpha i1 decreases expression EXP Haloperidol results in decreased expression of GNAI1 mRNA CTD PMID:15860345 NCBI chr 4:16,813,941...16,898,111
Ensembl chr 4:16,814,001...16,896,417
JBrowse link
G Gnai2 G protein subunit alpha i2 decreases expression EXP Haloperidol results in decreased expression of GNAI2 mRNA CTD PMID:15860345 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
G Gnai3 G protein subunit alpha i3 decreases expression EXP Haloperidol results in decreased expression of GNAI3 mRNA CTD PMID:15860345 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
JBrowse link
G Gnao1 G protein subunit alpha o1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of GNAO1 protein CTD PMID:34122009 NCBI chr19:11,034,874...11,192,502
Ensembl chr19:11,035,956...11,192,493
JBrowse link
G Gnas GNAS complex locus decreases expression EXP Haloperidol results in decreased expression of GNAS mRNA CTD PMID:15860345 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions EXP Haloperidol inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein] CTD PMID:18603625 NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 affects expression
multiple interactions
EXP
ISO
Haloperidol affects the expression of GOT2 mRNA
[Cuprizone co-treated with Haloperidol] results in increased expression of GOT2 protein
CTD PMID:15860345 PMID:34122009 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO Haloperidol results in increased expression of GPX1 mRNA CTD PMID:14647396 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 decreases expression EXP Haloperidol results in decreased expression of GRIA1 mRNA CTD PMID:15860345 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 increases expression EXP Haloperidol results in increased expression of GRIK2 mRNA CTD PMID:18923069 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375
JBrowse link
G Grik4 glutamate ionotropic receptor kainate type subunit 4 increases expression EXP Haloperidol results in increased expression of GRIK4 mRNA CTD PMID:15860345 NCBI chr 8:42,903,043...43,331,990
Ensembl chr 8:42,905,056...43,193,751
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 increases expression ISO
EXP
Haloperidol results in increased expression of GRIK5 mRNA CTD PMID:14647396 PMID:15860345 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression
increases expression
EXP Haloperidol results in decreased expression of GRIN1 mRNA
Haloperidol results in increased expression of GRIN1 mRNA
CTD PMID:12020038 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A decreases expression EXP Haloperidol results in decreased expression of GRIN2A mRNA; Haloperidol results in decreased expression of GRIN2A protein CTD PMID:12608697 PMID:15860345 PMID:18061412 NCBI chr10:5,630,684...6,043,341
Ensembl chr10:5,631,369...6,044,637
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions
increases phosphorylation
ISO FYN gene mutant form inhibits the reaction [Haloperidol results in increased phosphorylation of GRIN2B protein] CTD PMID:16407246 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C increases expression EXP Haloperidol results in increased expression of GRIN2C mRNA CTD PMID:15860345 NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427
JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D decreases expression EXP Haloperidol results in decreased expression of GRIN2D mRNA CTD PMID:18923069 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793
JBrowse link
G Grin3b glutamate ionotropic receptor NMDA type subunit 3B increases expression EXP Haloperidol results in increased expression of GRIN3B mRNA CTD PMID:15860345 NCBI chr 7:9,730,861...9,737,183
Ensembl chr 7:9,730,862...9,737,183
JBrowse link
G Grk6 G protein-coupled receptor kinase 6 decreases expression EXP Haloperidol results in decreased expression of GRK6 mRNA CTD PMID:16715494 NCBI chr17:9,177,018...9,192,644
Ensembl chr17:9,177,019...9,192,644
JBrowse link
G Grm1 glutamate metabotropic receptor 1 increases expression EXP Haloperidol results in increased expression of GRM1 mRNA CTD PMID:15860345 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170
JBrowse link
G Grm2 glutamate metabotropic receptor 2 increases expression EXP Haloperidol results in increased expression of GRM2 mRNA CTD PMID:18923069 NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha increases expression
multiple interactions
EXP Haloperidol results in increased expression of GSK3A protein
DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3A protein]
CTD PMID:16144542 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases expression
EXP DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3B protein]
Haloperidol results in increased expression of GSK3B mRNA; Haloperidol results in increased expression of GSK3B protein
CTD PMID:16144542 PMID:19359144 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP Haloperidol results in increased expression of GSTM1 mRNA CTD PMID:15860345 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression EXP Haloperidol results in decreased expression of GSTM2 mRNA CTD PMID:15860345 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
decreases expression
ISO Haloperidol inhibits the reaction [GSTP1 protein results in decreased susceptibility to Doxorubicin]
Haloperidol results in decreased expression of GSTP1 mRNA
CTD PMID:15946544 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gtf2e1 general transcription factor IIE subunit 1 decreases expression ISO Haloperidol results in decreased expression of GTF2E1 protein CTD PMID:34122009 NCBI chr11:63,182,073...63,215,349
Ensembl chr11:63,182,349...63,213,942
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of HADHB protein CTD PMID:34122009 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
JBrowse link
G Hars1 histidyl-tRNA synthetase 1 increases expression ISO Haloperidol results in increased expression of HARS protein CTD PMID:34122009 NCBI chr18:28,381,649...28,398,699
Ensembl chr18:28,381,655...28,398,740
JBrowse link
G Hcfc1 host cell factor C1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of HCFC1 protein CTD PMID:34122009 NCBI chr  X:151,687,779...151,712,688
Ensembl chr  X:151,687,779...151,712,638
JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A increases expression ISO Haloperidol results in increased expression of HIGD1A mRNA CTD PMID:14647396 NCBI chr 8:121,514,152...121,523,382
Ensembl chr 8:121,514,156...121,523,443
JBrowse link
G Hist2h2aa2 histone cluster 2 H2A family member A2 increases expression ISO Haloperidol results in increased expression of H2AC18 mRNA CTD PMID:14647396 NCBI chr 2:183,801,369...183,801,987 JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases activity
multiple interactions
increases expression
ISO Haloperidol results in increased activity of HMGCR protein
[Haloperidol results in increased activity of HMGCR protein] which results in increased abundance of Cholesterol; [Haloperidol results in increased activity of HMGCR protein] which results in increased abundance of Triglycerides
Haloperidol results in increased expression of HMGCR mRNA
CTD PMID:16027736 PMID:17052361 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Haloperidol results in increased expression of HMGCS1 mRNA CTD PMID:16027736 PMID:17052361 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of HNRNPC protein CTD PMID:34122009 NCBI chr15:24,779,593...24,809,213
Ensembl chr15:24,779,450...24,809,183
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K decreases expression ISO Haloperidol results in decreased expression of HNRNPK protein CTD PMID:34122009 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
JBrowse link
G Homer1 homer scaffold protein 1 multiple interactions
increases expression
EXP Cycloserine inhibits the reaction [Haloperidol results in increased expression of HOMER1 mRNA] CTD PMID:12464447 PMID:15860345 PMID:20147574 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
JBrowse link
G Hpcal4 hippocalcin-like 4 decreases expression EXP Haloperidol results in decreased expression of HPCAL4 mRNA CTD PMID:12437575 NCBI chr 5:135,454,477...135,466,417
Ensembl chr 5:135,454,540...135,466,416
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 decreases expression ISO Haloperidol results in decreased expression of HSD17B4 protein CTD PMID:34122009 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 decreases expression
multiple interactions
ISO Haloperidol results in decreased expression of HSPG2 mRNA
HSPG2 gene results in increased susceptibility to [Haloperidol co-treated with Reserpine]
CTD PMID:20072119 NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of HSPH1 protein CTD PMID:34122009 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D decreases expression EXP Haloperidol results in decreased expression of HTR1D mRNA CTD PMID:16715494 NCBI chr 5:148,655,979...148,676,534
Ensembl chr 5:148,674,495...148,675,619
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A affects binding
multiple interactions
EXP
ISO
Haloperidol binds to HTR2A protein
[Phencyclidine co-treated with Haloperidol] affects the activity of HTR2A protein
CTD PMID:7520908 PMID:12191584 PMID:15380371 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C decreases expression EXP Haloperidol results in decreased expression of HTR2C mRNA CTD PMID:17868938 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287
JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression
increases expression
EXP Haloperidol results in decreased expression of ID2 mRNA
Haloperidol results in increased expression of ID2 mRNA
CTD PMID:12437575 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Ikbip IKBKB interacting protein multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of IKBIP protein CTD PMID:34122009 NCBI chr 7:25,579,759...25,598,548
Ensembl chr 7:25,579,832...25,605,162
JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Cannabidiol co-treated with Haloperidol] results in increased expression of IL10 protein CTD PMID:30217539 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO Cannabidiol inhibits the reaction [Haloperidol results in increased expression of IL1B protein] CTD PMID:30217539 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO Haloperidol results in increased expression of IL6 mRNA
Cannabidiol inhibits the reaction [Haloperidol results in increased expression of IL6 mRNA]
CTD PMID:30217539 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ilkap ILK associated serine/threonine phosphatase decreases expression EXP Haloperidol results in decreased expression of ILKAP mRNA CTD PMID:15860345 NCBI chr 9:91,966,440...91,988,791
Ensembl chr 9:91,966,441...91,988,892
JBrowse link
G Impdh1 inosine monophosphate dehydrogenase 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of IMPDH1 protein CTD PMID:34122009 NCBI chr 4:57,801,842...57,817,434
Ensembl chr 4:57,801,831...57,819,076
JBrowse link
G Inha inhibin subunit alpha decreases expression EXP Haloperidol results in decreased expression of INHA mRNA CTD PMID:16715494 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248
JBrowse link
G Inhbe inhibin subunit beta E increases expression ISO Haloperidol results in increased expression of INHBE mRNA CTD PMID:17175557 NCBI chr 7:63,177,558...63,178,983
Ensembl chr 7:63,176,219...63,179,172
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
decreases expression
EXP Haloperidol results in increased expression of JUN mRNA; Haloperidol results in increased expression of JUN protein
Haloperidol results in decreased expression of JUN mRNA
CTD PMID:12093589 PMID:12125044 PMID:15860345 PMID:18208916 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression
increases expression
EXP 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of JUNB mRNA]
Haloperidol results in decreased expression of JUNB mRNA
CTD PMID:12093589 PMID:19695244 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Kcna1 potassium voltage-gated channel subfamily A member 1 increases expression ISO Haloperidol results in increased expression of KCNA1 mRNA; Haloperidol results in increased expression of KCNA1 protein CTD PMID:18797397 NCBI chr 4:159,464,223...159,472,905
Ensembl chr 4:159,464,188...159,472,682
JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 decreases expression ISO Haloperidol results in decreased expression of KCNAB1 mRNA CTD PMID:18797397 NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity
ISO Haloperidol inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Haloperidol results in decreased activity of KCNH2 protein
CTD PMID:15671647 PMID:16278312 PMID:16494862 PMID:19583963 PMID:21158687 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kcnip3 potassium voltage-gated channel interacting protein 3 decreases expression ISO Haloperidol results in decreased expression of KCNIP3 mRNA; Haloperidol results in decreased expression of KCNIP3 protein CTD PMID:18797397 NCBI chr 3:114,677,027...114,742,923
Ensembl chr 3:114,677,030...114,743,556
JBrowse link
G Kdm1a lysine demethylase 1A multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of KDM1A protein CTD PMID:34122009 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G Kdr kinase insert domain receptor increases expression ISO Haloperidol results in increased expression of KDR protein CTD PMID:34122009 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Kif5c kinesin family member 5C decreases expression ISO Haloperidol results in decreased expression of KIF5C protein CTD PMID:34122009 NCBI chr 3:34,032,082...34,185,597
Ensembl chr 3:34,032,105...34,182,413
JBrowse link
G Kiz kizuna centrosomal protein multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of KIZ protein CTD PMID:34122009 NCBI chr 3:134,277,631...134,385,260
Ensembl chr 3:134,277,687...134,385,190
JBrowse link
G Klc1 kinesin light chain 1 decreases expression ISO Haloperidol results in decreased expression of KLC1 mRNA CTD PMID:18797397 NCBI chr 6:130,823,416...130,866,729
Ensembl chr 6:130,823,419...130,867,031
JBrowse link
G Klc4 kinesin light chain 4 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of KLC4 protein CTD PMID:34122009 NCBI chr 9:14,337,164...14,351,075
Ensembl chr 9:14,337,534...14,351,066
JBrowse link
G Klhdc2 kelch domain containing 2 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of KLHDC2 protein CTD PMID:34122009 NCBI chr 6:87,777,183...87,791,609
Ensembl chr 6:87,777,183...87,804,187
JBrowse link
G Kmt2a lysine methyltransferase 2A decreases expression ISO Haloperidol results in decreased expression of KMT2A mRNA CTD PMID:14647396 NCBI chr 8:45,116,771...45,193,320
Ensembl chr 8:45,118,814...45,193,181
JBrowse link
G Kpna4 karyopherin subunit alpha 4 increases expression ISO Haloperidol results in increased expression of KPNA4 protein CTD PMID:34122009 NCBI chr 2:153,319,380...153,381,085
Ensembl chr 2:153,324,273...153,381,081
JBrowse link
G Kras KRAS proto-oncogene, GTPase increases expression EXP Haloperidol results in increased expression of KRAS mRNA CTD PMID:15860345 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Kremen1 kringle containing transmembrane protein 1 multiple interactions
increases expression
ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of KREMEN1 protein
Haloperidol results in increased expression of KREMEN1 protein
CTD PMID:34122009 NCBI chr14:80,081,870...80,147,489
Ensembl chr14:80,084,403...80,147,516
JBrowse link
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 increases expression ISO Haloperidol results in increased expression of LAMTOR3 mRNA CTD PMID:14647396 NCBI chr 2:226,411,389...226,423,612
Ensembl chr 2:226,411,400...226,423,607
JBrowse link
G Ldhb lactate dehydrogenase B decreases expression
increases expression
ISO
EXP
Haloperidol results in decreased expression of LDHB mRNA
Haloperidol results in increased expression of LDHB mRNA
CTD PMID:15860345 PMID:16465460 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Haloperidol results in increased expression of LDLR mRNA CTD PMID:17052361 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lgals1 galectin 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of LGALS1 protein CTD PMID:34122009 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
JBrowse link
G Lipa lipase A, lysosomal acid type increases expression ISO Haloperidol results in increased expression of LIPA protein CTD PMID:34122009 NCBI chr 1:232,024,351...232,167,329
Ensembl chr 1:232,024,356...232,057,633
JBrowse link
G Mag myelin-associated glycoprotein decreases expression ISO Haloperidol results in decreased expression of MAG mRNA CTD PMID:17177202 NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656
JBrowse link
G Map1a microtubule-associated protein 1A increases expression
decreases expression
EXP
ISO
Haloperidol results in increased expression of MAP1A mRNA
Haloperidol results in decreased expression of MAP1A protein
CTD PMID:15860345 PMID:34122009 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899
JBrowse link
G Map2 microtubule-associated protein 2 increases expression EXP Haloperidol results in increased expression of MAP2 mRNA CTD PMID:15079866 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 decreases expression EXP Haloperidol results in decreased expression of MAP2K1 mRNA CTD PMID:15860345 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 decreases expression
increases expression
EXP
ISO
Haloperidol results in decreased expression of MAP2K2 mRNA
Haloperidol results in increased expression of MAP2K2 mRNA
CTD PMID:14647396 PMID:15860345 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 decreases expression EXP Haloperidol results in decreased expression of MAP2K5 mRNA CTD PMID:15860345 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression EXP Haloperidol results in increased expression of MAP3K1 mRNA CTD PMID:15860345 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 increases expression EXP Haloperidol results in increased expression of MAP3K12 mRNA CTD PMID:15860345 NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
decreases expression
ISO
EXP
Haloperidol results in increased phosphorylation of MAPK1 protein
[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]; Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]; CNR1 protein affects the reaction [[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]]; SL 327 inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]
Haloperidol results in decreased expression of MAPK1 mRNA
CTD PMID:12871586 PMID:15860345 PMID:28017790 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 affects expression EXP Haloperidol affects the expression of MAPK14 mRNA CTD PMID:15860345 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO Haloperidol results in increased phosphorylation of MAPK3 protein
[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]; Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]; CNR1 protein affects the reaction [[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]]; SL 327 inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]
CTD PMID:12871586 PMID:28017790 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk6 mitogen-activated protein kinase 6 affects expression EXP Haloperidol affects the expression of MAPK6 mRNA CTD PMID:15860345 NCBI chr 8:76,146,650...76,169,767
Ensembl chr 8:76,146,690...76,169,720
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation EXP Haloperidol results in increased phosphorylation of MAPK8 protein CTD PMID:17092607 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 affects expression EXP Haloperidol affects the expression of MAPK9 mRNA CTD PMID:15860345 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mapre1 microtubule-associated protein, RP/EB family, member 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of MAPRE1 protein CTD PMID:34122009 NCBI chr 3:142,218,846...142,246,990
Ensembl chr 3:142,212,955...142,246,983
JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor decreases expression EXP Haloperidol results in decreased expression of MAS1 mRNA CTD PMID:16715494 NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709
JBrowse link
G Mbp myelin basic protein decreases expression ISO Haloperidol results in decreased expression of MBP mRNA CTD PMID:17177202 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Mcam melanoma cell adhesion molecule increases expression ISO Haloperidol results in increased expression of MCAM protein CTD PMID:34122009 NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571
JBrowse link
G Mchr1 melanin-concentrating hormone receptor 1 affects binding ISO Haloperidol binds to MCHR1 protein CTD PMID:16983399 NCBI chr 7:112,761,554...112,764,746
Ensembl chr 7:112,761,554...112,764,032
JBrowse link
G Mmp10 matrix metallopeptidase 10 decreases expression ISO Haloperidol results in decreased expression of MMP10 protein CTD PMID:34122009 NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
JBrowse link
G Mog myelin oligodendrocyte glycoprotein decreases expression ISO Haloperidol results in decreased expression of MOG mRNA CTD PMID:17177202 NCBI chr20:1,513,137...1,523,473
Ensembl chr20:1,513,239...1,523,474
JBrowse link
G Mrps31 mitochondrial ribosomal protein S31 increases expression ISO Haloperidol results in increased expression of MRPS31 protein CTD PMID:34122009 NCBI chr16:69,601,349...69,621,609
Ensembl chr16:69,601,349...69,630,654
JBrowse link
G Myadm myeloid-associated differentiation marker multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of MYADM protein CTD PMID:34122009 NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:65,864,173...65,874,035
JBrowse link
G Myo5b myosin Vb decreases expression ISO Haloperidol results in decreased expression of MYO5B protein CTD PMID:34122009 NCBI chr18:68,038,759...68,341,568
Ensembl chr18:68,038,759...68,338,745
JBrowse link
G Nap1l3 nucleosome assembly protein 1-like 3 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of NAP1L3 protein CTD PMID:34122009 NCBI chr  X:88,347,595...88,350,393
Ensembl chr  X:88,347,598...88,350,393
JBrowse link
G Ncan neurocan decreases expression ISO Haloperidol results in decreased expression of NCAN mRNA CTD PMID:18797397 NCBI chr16:19,301,969...19,328,436
Ensembl chr16:19,301,969...19,328,436
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H decreases expression ISO Haloperidol results in decreased expression of NCAPH protein CTD PMID:34122009 NCBI chr 3:114,371,937...114,399,223
Ensembl chr 3:114,371,941...114,399,180
JBrowse link
G Ncl nucleolin increases expression ISO Haloperidol results in increased expression of NCL mRNA CTD PMID:14647396 NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136
JBrowse link
G Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of NDUFV1 protein CTD PMID:34122009 NCBI chr 1:201,300,365...201,305,461
Ensembl chr 1:201,299,985...201,305,466
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase decreases expression ISO Haloperidol results in decreased expression of NEDD4 mRNA CTD PMID:18797397 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression EXP Haloperidol results in decreased expression of NFKB1 protein CTD PMID:16500086 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Ngfr nerve growth factor receptor decreases expression EXP Haloperidol results in decreased expression of NGFR mRNA CTD PMID:16513140 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Nifk nucleolar protein interacting with the FHA domain of MKI67 decreases expression ISO Haloperidol results in decreased expression of NIFK protein CTD PMID:34122009 NCBI chr13:29,393,303...29,403,387
Ensembl chr13:29,393,286...29,405,896
JBrowse link
G Nop14 NOP14 nucleolar protein multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of NOP14 protein CTD PMID:34122009 NCBI chr14:76,081,318...76,102,454
Ensembl chr14:76,080,793...76,102,453
JBrowse link
G Nop53 NOP53 ribosome biogenesis factor increases expression ISO Haloperidol results in increased expression of NOP53 mRNA CTD PMID:14647396 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
ISO Cannabidiol inhibits the reaction [Haloperidol results in increased expression of NOS2 mRNA] CTD PMID:30217539 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nppa natriuretic peptide A affects activity EXP Haloperidol affects the activity of NPPA protein modified form CTD PMID:1363893 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nptx2 neuronal pentraxin 2 decreases expression EXP Haloperidol results in decreased expression of NPTX2 mRNA CTD PMID:18208916 NCBI chr12:10,037,435...10,048,345
Ensembl chr12:10,037,435...10,048,345
JBrowse link
G Npy neuropeptide Y multiple interactions
decreases expression
increases expression
EXP Haloperidol promotes the reaction [Amphetamine results in decreased expression of NPY protein]
Haloperidol results in decreased expression of NPY mRNA
Haloperidol results in increased expression of NPY protein
CTD PMID:7644023 PMID:15985714 PMID:16516965 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of NQO1 protein CTD PMID:34122009 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO Haloperidol results in increased expression of NR0B2 mRNA CTD PMID:17175557 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression EXP Haloperidol results in increased expression of NR1D1 mRNA CTD PMID:11564422 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 affects response to substance
decreases expression
increases expression
multiple interactions
ISO
EXP
NR4A1 affects the susceptibility to Haloperidol
Haloperidol results in decreased expression of NR4A1 mRNA
Haloperidol results in increased expression of NR4A1 mRNA
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of NR4A1 mRNA]
CTD PMID:10987852 PMID:11564422 PMID:14603264 PMID:19695244 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression EXP Haloperidol results in increased expression of NR4A3 mRNA CTD PMID:19695244 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
JBrowse link
G Nrg1 neuregulin 1 increases expression EXP Haloperidol results in increased expression of NRG1 protein CTD PMID:18184445 PMID:26961615 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase decreases expression EXP
ISO
Haloperidol results in decreased expression of NSF mRNA
Haloperidol results in decreased expression of NSF protein
CTD PMID:15860345 PMID:34122009 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386
JBrowse link
G Nts neurotensin multiple interactions
increases expression
ISO
EXP
SLC6A3 protein promotes the reaction [Haloperidol results in increased expression of NTS mRNA]
8-(3-chlorostyryl)caffeine inhibits the reaction [Haloperidol results in increased expression of NTS mRNA]; Theophylline inhibits the reaction [Haloperidol results in increased expression of NTS mRNA]
Haloperidol results in increased expression of NTS mRNA; Haloperidol results in increased expression of NTS protein
CTD PMID:10199625 PMID:11120399 PMID:11602683 PMID:12887421 PMID:14603264 More... NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423
JBrowse link
G Numbl NUMB-like, endocytic adaptor protein decreases expression ISO Haloperidol results in decreased expression of NUMBL mRNA CTD PMID:18797397 NCBI chr 1:82,549,814...82,573,788
Ensembl chr 1:82,550,054...82,573,776
JBrowse link
G Nup54 nucleoporin 54 decreases expression ISO Haloperidol results in decreased expression of NUP54 protein CTD PMID:34122009 NCBI chr14:15,617,630...15,636,029
Ensembl chr14:15,617,679...15,636,028
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Haloperidol results in increased expression of NUPR1 mRNA CTD PMID:17175557 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Oat ornithine aminotransferase multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of OAT protein CTD PMID:34122009 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 affects response to substance ISO OPRL1 affects the susceptibility to Haloperidol CTD PMID:16237164 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions ISO OPRM1 protein inhibits the reaction [Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]] CTD PMID:20184921 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Osbpl8 oxysterol binding protein-like 8 increases expression ISO Haloperidol results in increased expression of OSBPL8 mRNA CTD PMID:14647396 NCBI chr 7:46,596,944...46,749,888
Ensembl chr 7:46,596,983...46,749,888
JBrowse link
G Park7 Parkinsonism associated deglycase increases expression ISO Haloperidol results in increased expression of PARK7 mRNA CTD PMID:14647396 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 decreases expression ISO Haloperidol results in decreased expression of PCMT1 protein CTD PMID:34122009 NCBI chr 1:2,111,756...2,160,354
Ensembl chr 1:2,111,763...2,159,201
JBrowse link
G Pcsk1n proprotein convertase subtilisin/kexin type 1 inhibitor increases expression ISO Haloperidol results in increased expression of PCSK1N mRNA CTD PMID:14647396 NCBI chr  X:14,580,036...14,583,478
Ensembl chr  X:14,580,038...14,583,566
JBrowse link
G Pde10a phosphodiesterase 10A increases expression EXP Haloperidol results in increased expression of PDE10A mRNA; Haloperidol results in increased expression of PDE10A protein CTD PMID:18222493 NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:51,770,132...52,216,563
JBrowse link
G Pde1b phosphodiesterase 1B increases expression EXP
ISO
Haloperidol results in increased expression of PDE1B mRNA; Haloperidol results in increased expression of PDE1B protein CTD PMID:14647396 PMID:18222493 NCBI chr 7:134,627,378...134,654,581
Ensembl chr 7:134,627,322...134,654,580
JBrowse link
G Pde4a phosphodiesterase 4A decreases expression EXP Haloperidol results in decreased expression of PDE4A protein CTD PMID:20222156 NCBI chr 8:19,706,649...19,751,937
Ensembl chr 8:19,703,290...19,751,961
JBrowse link
G Pdlim5 PDZ and LIM domain 5 decreases expression ISO Haloperidol results in decreased expression of PDLIM5 protein CTD PMID:34122009 NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275
JBrowse link
G Pdzrn3 PDZ domain containing RING finger 3 decreases expression ISO Haloperidol results in decreased expression of PDZRN3 protein CTD PMID:34122009 NCBI chr 4:133,770,736...133,996,959
Ensembl chr 4:133,770,736...133,996,959
JBrowse link
G Penk proenkephalin multiple interactions
increases expression
ISO
EXP
3,4-dicarboxyphenylglycine promotes the reaction [Haloperidol results in increased expression of PENK mRNA]; Docosahexaenoic Acids inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; Tretinoin inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]
1-aminocyclopentane-1,2,4-tricarboxylic acid inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; 1-aminoindan-1,5-dicarboxylic acid inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; 2-(2,3-dicarboxycyclopropyl)glycine promotes the reaction [Haloperidol results in increased expression of PENK mRNA]; 5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; Memantine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; Scopolamine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]
Haloperidol results in increased expression of PENK mRNA; Haloperidol results in increased expression of PENK protein
CTD PMID:3838946 PMID:7637876 PMID:12373537 PMID:12727308 PMID:12834887 More... NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
JBrowse link
G Per1 period circadian regulator 1 increases expression ISO Haloperidol results in increased expression of PER1 mRNA CTD PMID:27746588 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431
JBrowse link
G Pfdn5 prefoldin subunit 5 increases expression ISO Haloperidol results in increased expression of PFDN5 mRNA CTD PMID:14647396 NCBI chr 7:133,451,778...133,456,516
Ensembl chr 7:133,451,453...133,456,516
JBrowse link
G Pfkp phosphofructokinase, platelet increases expression
multiple interactions
EXP
ISO
Haloperidol results in increased expression of PFKP mRNA
[Cuprizone co-treated with Haloperidol] results in increased expression of PFKP protein
CTD PMID:15860345 PMID:34122009 NCBI chr17:63,729,743...63,794,021
Ensembl chr17:63,729,780...63,794,018
JBrowse link
G Pfn1 profilin 1 increases expression ISO Haloperidol results in increased expression of PFN1 protein CTD PMID:34122009 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631
JBrowse link
G Pgk1 phosphoglycerate kinase 1 increases expression EXP Haloperidol results in increased expression of PGK1 mRNA CTD PMID:15860345 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Phactr1 phosphatase and actin regulator 1 increases expression ISO Haloperidol results in increased expression of PHACTR1 mRNA CTD PMID:14647396 NCBI chr17:21,560,364...22,040,166
Ensembl chr17:21,562,721...22,039,831
JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein decreases expression EXP Haloperidol results in decreased expression of PICALM mRNA CTD PMID:15860345 NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 decreases expression EXP Haloperidol results in decreased expression of PIK3R3 mRNA CTD PMID:16715494 NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583
JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta decreases expression EXP Haloperidol results in decreased expression of PKIB mRNA CTD PMID:15860345 NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187
JBrowse link
G Pkm pyruvate kinase M1/2 increases expression EXP Haloperidol results in increased expression of PKM mRNA CTD PMID:15860345 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Plp1 proteolipid protein 1 decreases expression ISO Haloperidol results in decreased expression of PLP1 mRNA CTD PMID:17177202 PMID:18797397 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032
JBrowse link
G Plpbp pyridoxal phosphate binding protein increases expression ISO Haloperidol results in increased expression of PROSC protein CTD PMID:34122009 NCBI chr16:65,003,292...65,014,886
Ensembl chr16:65,002,223...65,014,886
JBrowse link
G Pls3 plastin 3 decreases expression ISO Haloperidol results in decreased expression of PLS3 protein CTD PMID:34122009 NCBI chr  X:111,589,193...111,683,908
Ensembl chr  X:111,589,254...111,683,891
JBrowse link
G Pmpca peptidase, mitochondrial processing subunit alpha increases expression ISO Haloperidol results in increased expression of PMPCA protein CTD PMID:34122009 NCBI chr 3:9,207,731...9,216,846
Ensembl chr 3:9,207,717...9,216,844
JBrowse link
G Ppa1 inorganic pyrophosphatase 1 increases expression ISO Haloperidol results in increased expression of PPA1 protein CTD PMID:34122009 NCBI chr20:29,590,733...29,617,711
Ensembl chr20:29,590,707...29,619,215
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO [Cannabidiol co-treated with Haloperidol] results in increased expression of PPARGC1A protein CTD PMID:30217539 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A decreases expression EXP Haloperidol results in decreased expression of PPM1A mRNA CTD PMID:15860345 NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697
JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B decreases expression EXP Haloperidol results in decreased expression of PPM1B mRNA CTD PMID:15860345 NCBI chr 6:9,646,695...9,707,471
Ensembl chr 6:9,655,765...9,707,974
JBrowse link
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent, 1F multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of PPM1F protein CTD PMID:34122009 NCBI chr11:84,064,422...84,094,410
Ensembl chr11:84,064,420...84,094,340
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta decreases expression EXP Haloperidol results in decreased expression of PPP1CB mRNA CTD PMID:15860345 NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824
JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma decreases expression EXP Haloperidol results in decreased expression of PPP1CC mRNA CTD PMID:15860345 NCBI chr12:34,383,072...34,400,553
Ensembl chr12:34,383,072...34,400,553
JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory (inhibitor) subunit 14B multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of PPP1R14B protein CTD PMID:34122009 NCBI chr 1:204,165,210...204,167,320
Ensembl chr 1:204,163,299...204,167,319
JBrowse link
G Ppp1r1a protein phosphatase 1, regulatory (inhibitor) subunit 1A decreases expression EXP Haloperidol results in decreased expression of PPP1R1A mRNA CTD PMID:15860345 NCBI chr 7:134,654,578...134,662,236
Ensembl chr 7:134,654,579...134,662,230
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B increases phosphorylation ISO Haloperidol results in increased phosphorylation of PPP1R1B protein CTD PMID:12871586 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775
JBrowse link
G Ppp1r2 protein phosphatase 1, regulatory (inhibitor) subunit 2 decreases expression EXP Haloperidol results in decreased expression of PPP1R2 mRNA CTD PMID:15860345 NCBI chr11:69,472,676...69,494,468
Ensembl chr11:69,472,555...69,494,463
JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B decreases expression EXP Haloperidol results in decreased expression of PPP1R9B protein CTD PMID:16844384 NCBI chr10:79,938,055...79,954,085
Ensembl chr10:79,938,066...79,954,083
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha decreases expression EXP Haloperidol results in decreased expression of PPP2CA mRNA CTD PMID:15860345 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta decreases expression EXP Haloperidol results in decreased expression of PPP2CB mRNA CTD PMID:15860345 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha increases expression EXP Haloperidol results in increased expression of PPP2R1A mRNA CTD PMID:15860345 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129
JBrowse link
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha decreases expression EXP Haloperidol results in decreased expression of PPP2R2A mRNA CTD PMID:15860345 NCBI chr15:41,204,659...41,263,924
Ensembl chr15:41,204,200...41,263,924
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha multiple interactions
decreases expression
EXP [Haloperidol binds to and results in decreased activity of DRD2 protein] which results in increased expression of PPP3CA protein
Haloperidol results in decreased expression of PPP3CA mRNA; Haloperidol results in decreased expression of PPP3CA protein
CTD PMID:16033416 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit decreases expression
multiple interactions
ISO Haloperidol results in decreased expression of PPP5C mRNA
[Cuprizone co-treated with Haloperidol] results in decreased expression of PPP5C protein
CTD PMID:14647396 PMID:34122009 NCBI chr 1:77,690,203...77,714,507
Ensembl chr 1:77,690,208...77,714,456
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha increases expression EXP Haloperidol results in increased expression of PRKACA mRNA CTD PMID:15860345 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta increases expression EXP Haloperidol results in increased expression of PRKACB mRNA CTD PMID:15860345 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198
JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha multiple interactions
increases expression
EXP
ISO
Haloperidol promotes the reaction [Cyclic AMP binds to PRKAR2A protein]
Haloperidol results in increased expression of PRKAR2A mRNA; Haloperidol results in increased expression of PRKAR2A protein
[Cuprizone co-treated with Haloperidol] results in decreased expression of PRKAR2A protein
CTD PMID:11907174 PMID:34122009 NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:109,395,833...109,455,628
JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta multiple interactions
decreases expression
increases expression
EXP Haloperidol promotes the reaction [Cyclic AMP binds to PRKAR2B protein]
Haloperidol results in decreased expression of PRKAR2B mRNA
Haloperidol results in increased expression of PRKAR2B mRNA; Haloperidol results in increased expression of PRKAR2B protein
CTD PMID:11907174 PMID:15860345 NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933
JBrowse link
G Prkcb protein kinase C, beta multiple interactions
increases expression
EXP [Haloperidol co-treated with Fluvoxamine] affects the expression of PRKCB protein
Haloperidol results in increased expression of PRKCB mRNA
CTD PMID:15860345 PMID:15967061 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Prkce protein kinase C, epsilon increases expression EXP Haloperidol results in increased expression of PRKCE mRNA CTD PMID:15860345 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prkcsh protein kinase C substrate 80K-H multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of PRKCSH protein CTD PMID:34122009 NCBI chr 8:20,534,787...20,546,493
Ensembl chr 8:20,534,880...20,546,492
JBrowse link
G Prkcz protein kinase C, zeta increases expression EXP Haloperidol results in increased expression of PRKCZ mRNA CTD PMID:15860345 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
JBrowse link
G Prl prolactin affects expression
increases secretion
increases expression
multiple interactions
ISO
EXP
Haloperidol affects the expression of PRL protein
Haloperidol results in increased secretion of PRL protein
Haloperidol results in increased expression of PRL protein
Haloperidol inhibits the reaction [Aripiprazole results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [cabergoline results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [Dopamine results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [talipexole results in decreased secretion of PRL protein]; LHRH, N-acetyl-(4-chlorophenylalanyl)(1)-(4-chlorophenylalanyl)(2)-tryptophyl(3)-arginyl(6)-alanine(10)- inhibits the reaction [Haloperidol results in increased expression of PRL protein]; Triptorelin Pamoate inhibits the reaction [Haloperidol results in increased expression of PRL protein]
CTD PMID:1304992 PMID:1380082 PMID:2136057 PMID:3019639 PMID:3158510 More... NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Prpf19 pre-mRNA processing factor 19 increases expression ISO Haloperidol results in increased expression of PRPF19 protein CTD PMID:34122009 NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662
JBrowse link
G Prpf38b pre-mRNA processing factor 38B decreases expression ISO Haloperidol results in decreased expression of PRPF38B mRNA CTD PMID:14647396 NCBI chr 2:196,553,224...196,562,271
Ensembl chr 2:196,553,225...196,562,250
JBrowse link
G Prrc2a proline-rich coiled-coil 2A decreases expression ISO Haloperidol results in decreased expression of PRRC2A mRNA CTD PMID:18797397 NCBI chr20:3,658,391...3,674,143
Ensembl chr20:3,658,695...3,674,130
JBrowse link
G Prxl2a peroxiredoxin like 2A multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of PRXL2A protein CTD PMID:34122009 NCBI chr16:16,866,601...16,886,378
Ensembl chr16:16,866,603...16,886,433
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 decreases expression EXP Haloperidol results in decreased expression of PSMB9 mRNA CTD PMID:16452686 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512
JBrowse link
G Psmd12 proteasome 26S subunit, non-ATPase 12 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of PSMD12 protein CTD PMID:34122009 NCBI chr10:92,438,223...92,457,323
Ensembl chr10:92,438,298...92,457,287
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Haloperidol results in increased expression of PTGS2 mRNA CTD PMID:30217539 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptma prothymosin alpha increases expression ISO Haloperidol results in increased expression of PTMA protein CTD PMID:34122009 NCBI chr 9:87,176,251...87,180,333
Ensembl chr 9:87,176,230...87,180,333
JBrowse link
G Ptms parathymosin increases expression ISO Haloperidol results in increased expression of PTMS mRNA CTD PMID:14647396 NCBI chr 4:157,722,384...157,726,575
Ensembl chr 4:157,722,386...157,727,009
JBrowse link
G Pura purine rich element binding protein A increases expression ISO Haloperidol results in increased expression of PURA protein CTD PMID:34122009 NCBI chr18:27,884,618...27,905,500
Ensembl chr18:27,884,556...27,905,513
JBrowse link
G Purb purine rich element binding protein B decreases expression ISO Haloperidol results in decreased expression of PURB protein CTD PMID:34122009 NCBI chr14:81,342,374...81,344,857
Ensembl chr14:81,336,448...81,351,432
JBrowse link
G Pvalb parvalbumin multiple interactions EXP Haloperidol inhibits the reaction [Phencyclidine results in decreased expression of PVALB mRNA] CTD PMID:12589379 NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of PYCR1 protein CTD PMID:34122009 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549
JBrowse link
G Pygm glycogen phosphorylase, muscle associated decreases expression ISO Haloperidol results in decreased expression of PYGM protein CTD PMID:34122009 NCBI chr 1:203,690,550...203,705,369
Ensembl chr 1:203,690,533...203,705,368
JBrowse link
G Qki QKI, KH domain containing RNA binding increases expression ISO Haloperidol results in increased expression of QKI mRNA alternative form CTD PMID:19335891 NCBI chr 1:50,387,698...50,501,568
Ensembl chr 1:50,387,698...50,498,831
JBrowse link
G Rab10 RAB10, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB10 mRNA CTD PMID:15860345 NCBI chr 6:26,267,081...26,319,739
Ensembl chr 6:26,266,859...26,320,193
JBrowse link
G Rab11a RAB11a, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB11A mRNA CTD PMID:15860345 NCBI chr 8:65,223,698...65,246,461
Ensembl chr 8:65,222,949...65,246,525
JBrowse link
G Rab12 RAB12, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB12 mRNA CTD PMID:12437575 NCBI chr 9:106,480,301...106,506,895
Ensembl chr 9:106,480,301...106,506,910
JBrowse link
G Rab28 RAB28, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB28 mRNA CTD PMID:15860345 NCBI chr14:69,245,846...69,322,968
Ensembl chr14:69,245,854...69,322,967
JBrowse link
G Rab4a RAB4A, member RAS oncogene family decreases expression EXP Haloperidol results in decreased expression of RAB4A mRNA CTD PMID:15860345 NCBI chr19:51,795,613...51,822,706
Ensembl chr19:51,795,613...51,822,703
JBrowse link
G Rab5a RAB5A, member RAS oncogene family multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RAB5A protein CTD PMID:34122009 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873
JBrowse link
G Rab6a RAB6A, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB6A mRNA CTD PMID:15860345 NCBI chr 1:154,957,870...155,008,922
Ensembl chr 1:154,958,189...154,996,715
JBrowse link
G Rab7a RAB7A, member RAS oncogene family decreases expression EXP Haloperidol results in decreased expression of RAB7A mRNA CTD PMID:15860345 NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889
JBrowse link
G Rab8a RAB8A, member RAS oncogene family decreases expression EXP Haloperidol results in decreased expression of RAB8A mRNA CTD PMID:15860345 NCBI chr16:17,654,027...17,675,385
Ensembl chr16:17,654,034...17,675,678
JBrowse link
G Rac1 Rac family small GTPase 1 increases expression EXP Haloperidol results in increased expression of RAC1 mRNA CTD PMID:15860345 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rala RAS like proto-oncogene A increases expression EXP Haloperidol results in increased expression of RALA mRNA CTD PMID:15860345 NCBI chr17:47,092,139...47,145,192
Ensembl chr17:47,092,207...47,144,063
JBrowse link
G Ralb RAS like proto-oncogene B increases expression EXP Haloperidol results in increased expression of RALB mRNA CTD PMID:15860345 NCBI chr13:30,588,036...30,624,199
Ensembl chr13:30,588,033...30,624,202
JBrowse link
G Ranbp3 RAN binding protein 3 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of RANBP3 protein CTD PMID:34122009 NCBI chr 9:1,507,233...1,544,460
Ensembl chr 9:1,507,361...1,544,460
JBrowse link
G Rap1b RAP1B, member of RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAP1B mRNA CTD PMID:15860345 NCBI chr 7:53,423,039...53,456,388
Ensembl chr 7:53,423,130...53,456,370
JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 decreases expression ISO Haloperidol results in decreased expression of RAPGEF4 mRNA CTD PMID:18797397 NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316
JBrowse link
G Rarb retinoic acid receptor, beta increases expression EXP Haloperidol results in increased expression of RARB mRNA alternative form CTD PMID:11564422 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 affects localization EXP Haloperidol affects the localization of RASGRF1 protein CTD PMID:17092607 NCBI chr 8:90,445,154...90,574,274
Ensembl chr 8:90,445,154...90,574,269
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 decreases expression EXP Haloperidol results in decreased expression of RASGRP1 mRNA CTD PMID:15860345 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
JBrowse link
G Rcn1 reticulocalbin 1 multiple interactions
decreases expression
ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RCN1 protein
Haloperidol results in decreased expression of RCN1 protein
CTD PMID:34122009 NCBI chr 3:91,841,052...91,855,295
Ensembl chr 3:91,841,052...91,855,295
JBrowse link
G Rdh11 retinol dehydrogenase 11 decreases expression ISO Haloperidol results in decreased expression of RDH11 protein CTD PMID:34122009 NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252
JBrowse link
G Rdx radixin decreases expression ISO Haloperidol results in decreased expression of RDX protein CTD PMID:34122009 NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression EXP Haloperidol results in increased expression of RELA protein CTD PMID:18554768 PMID:18590723 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Reln reelin decreases expression EXP Haloperidol results in decreased expression of RELN mRNA; Haloperidol results in decreased expression of RELN protein CTD PMID:19359144 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211
JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression EXP Haloperidol results in increased expression of RGS2 mRNA CTD PMID:11409749 PMID:11516571 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Rgs4 regulator of G-protein signaling 4 increases expression EXP Haloperidol results in increased expression of RGS4 mRNA CTD PMID:15860345 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
JBrowse link
G Rgs8 regulator of G-protein signaling 8 increases expression EXP Haloperidol results in increased expression of RGS8 mRNA CTD PMID:15860345 NCBI chr13:65,804,703...65,848,953
Ensembl chr13:65,804,797...65,846,807
JBrowse link
G Rgs9 regulator of G-protein signaling 9 affects response to substance ISO RGS9 affects the susceptibility to Haloperidol CTD PMID:15728856 NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892
JBrowse link
G Rhoa ras homolog family member A decreases expression EXP Haloperidol results in decreased expression of RHOA mRNA CTD PMID:15860345 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 decreases expression EXP Haloperidol results in decreased expression of RIMS1 mRNA CTD PMID:15860345 NCBI chr 9:24,696,959...25,196,368
Ensembl chr 9:24,698,854...25,196,631
JBrowse link
G Rorb RAR-related orphan receptor B decreases expression EXP Haloperidol results in decreased expression of RORB mRNA CTD PMID:11564422 NCBI chr 1:216,363,629...216,544,390
Ensembl chr 1:216,363,629...216,544,390
JBrowse link
G Rpl13 ribosomal protein L13 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RPL13 protein CTD PMID:34122009 NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014
JBrowse link
G Rpl18a ribosomal protein L18A multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RPL18A protein CTD PMID:34122009 NCBI chr16:18,542,572...18,544,578
Ensembl chr16:18,542,566...18,545,546
JBrowse link
G Rpl19 ribosomal protein L19 decreases expression
multiple interactions
ISO Haloperidol results in decreased expression of RPL19 protein
[Cuprizone co-treated with Haloperidol] results in increased expression of RPL19 protein
CTD PMID:34122009 NCBI chr10:83,022,503...83,026,030
Ensembl chr10:83,019,257...83,052,112
JBrowse link
G Rpl30 ribosomal protein L30 increases expression ISO Haloperidol results in increased expression of RPL30 protein CTD PMID:34122009 NCBI chr 7:65,648,470...65,651,363
Ensembl chr 7:65,645,991...65,651,363
Ensembl chr10:65,645,991...65,651,363
Ensembl chr10:65,645,991...65,651,363
JBrowse link
G Rpl6 ribosomal protein L6 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RPL6 protein CTD PMID:34122009 NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921
JBrowse link
G Rpl8 ribosomal protein L8 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RPL8 protein CTD PMID:34122009 NCBI chr 7:108,626,194...108,628,485
Ensembl chr 7:108,622,324...108,628,482
JBrowse link
G Rplp0l1 ribosomal protein lateral stalk subunit P0 like 1 decreases expression ISO Haloperidol results in decreased expression of RPLP0P6 protein CTD PMID:34122009 NCBI chr 2:191,921,503...191,922,661
Ensembl chr 2:191,921,574...191,922,646
JBrowse link
G Rplp2 ribosomal protein lateral stalk subunit P2 increases expression ISO Haloperidol results in increased expression of RPLP2 mRNA CTD PMID:14647396 NCBI chr 1:196,546,086...196,548,636
Ensembl chr 1:196,546,352...196,548,645
JBrowse link
G Rps10 ribosomal protein S10 increases expression ISO Haloperidol results in increased expression of RPS10 mRNA CTD PMID:14647396 NCBI chr20:5,694,313...5,698,922
Ensembl chr20:5,694,313...5,699,044
JBrowse link
G Rps16 ribosomal protein S16 decreases expression ISO Haloperidol results in decreased expression of RPS16 protein CTD PMID:34122009 NCBI chr 1:83,643,066...83,646,056
Ensembl chr 1:83,643,130...83,646,206
JBrowse link
G Rps27 ribosomal protein S27 increases expression ISO Haloperidol results in increased expression of RPS27 protein CTD PMID:34122009 NCBI chr 2:175,665,858...175,666,963
Ensembl chr 2:175,665,853...175,666,964
JBrowse link
G Rps27a ribosomal protein S27a multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RPS27A protein CTD PMID:34122009 NCBI chr14:103,285,734...103,288,011
Ensembl chr14:103,285,734...103,288,011
JBrowse link
G Rps9 ribosomal protein S9 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RPS9 protein CTD PMID:34122009 NCBI chr 1:65,511,723...65,515,121
Ensembl chr 1:65,511,723...65,515,123
JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression EXP Haloperidol results in increased expression of RRAD mRNA CTD PMID:15860345 NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417
JBrowse link
G Rrbp1 ribosome binding protein 1 decreases expression ISO Haloperidol results in decreased expression of RRBP1 protein CTD PMID:34122009 NCBI chr 3:131,314,996...131,376,930
Ensembl chr 3:131,314,998...131,376,981
JBrowse link
G Rsf1 remodeling and spacing factor 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of RSF1 protein CTD PMID:34122009 NCBI chr 1:151,892,055...152,015,089
Ensembl chr 1:151,892,434...152,009,051
JBrowse link
G Rtn4 reticulon 4 decreases expression ISO Haloperidol results in decreased expression of RTN4 mRNA CTD PMID:18797397 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686
JBrowse link
G Rxrg retinoid X receptor gamma affects response to substance
increases expression
ISO
EXP
RXRG protein affects the susceptibility to Haloperidol
Haloperidol results in increased expression of RXRG mRNA alternative form
CTD PMID:10336693 PMID:11564422 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
JBrowse link
G S100a9 S100 calcium binding protein A9 decreases expression ISO Haloperidol results in decreased expression of S100A9 mRNA CTD PMID:18797397 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G Sae1 SUMO1 activating enzyme subunit 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SAE1 protein CTD PMID:34122009 NCBI chr 1:77,030,961...77,086,937
Ensembl chr 1:77,030,965...77,086,986
JBrowse link
G Sars1 seryl-tRNA synthetase 1 decreases expression ISO Haloperidol results in decreased expression of SARS protein CTD PMID:34122009 NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277
JBrowse link
G Satb2 SATB homeobox 2 decreases expression ISO Haloperidol results in decreased expression of SATB2 protein CTD PMID:34122009 NCBI chr 9:58,348,027...58,534,256
Ensembl chr 9:58,350,246...58,530,707
JBrowse link
G Sbds Sbds, ribosome maturation factor multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of SBDS protein CTD PMID:34122009 NCBI chr12:26,420,410...26,429,650
Ensembl chr12:26,420,414...26,429,649
JBrowse link
G Sc5d sterol-C5-desaturase increases expression ISO Haloperidol results in increased expression of SC5D mRNA CTD PMID:17052361 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273
JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO Haloperidol results in increased expression of SCD mRNA CTD PMID:16027736 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Sec61a1 SEC61 translocon subunit alpha 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SEC61A1 protein CTD PMID:34122009 NCBI chr 4:120,973,519...120,987,871
Ensembl chr 4:120,960,626...120,987,925
JBrowse link
G Sec63 SEC63 homolog, protein translocation regulator increases expression ISO Haloperidol results in increased expression of SEC63 protein CTD PMID:34122009 NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055
JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N increases expression ISO Haloperidol results in increased expression of SERPINA3 mRNA; Haloperidol results in increased expression of SERPINA3 protein CTD PMID:17175557 PMID:34122009 NCBI chr 6:123,323,632...123,331,166
Ensembl chr 6:123,323,629...123,332,433
JBrowse link
G Serpini1 serpin family I member 1 decreases expression ISO Haloperidol results in decreased expression of SERPINI1 mRNA CTD PMID:18797397 NCBI chr 2:160,346,403...160,433,135
Ensembl chr 2:160,346,758...160,433,135
JBrowse link
G Sf3b4 splicing factor 3B subunit 4 decreases expression ISO Haloperidol results in decreased expression of SF3B4 protein CTD PMID:34122009 NCBI chr 2:183,732,791...183,737,545
Ensembl chr 2:183,732,754...183,737,959
JBrowse link
G Sgcd sarcoglycan, delta multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SGCD protein CTD PMID:34122009 NCBI chr10:31,346,480...32,328,364
Ensembl chr10:31,280,511...31,724,840
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression EXP Haloperidol results in increased expression of SGK1 mRNA CTD PMID:16452686 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
JBrowse link
G Sh3kbp1 SH3 domain-containing kinase-binding protein 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SH3KBP1 protein CTD PMID:34122009 NCBI chr  X:34,877,862...35,223,013
Ensembl chr  X:34,877,866...35,222,747
JBrowse link
G Sh3pxd2b SH3 and PX domains 2B multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of SH3PXD2B protein CTD PMID:34122009 NCBI chr10:16,918,611...17,027,499
Ensembl chr10:16,918,679...17,005,170
JBrowse link
G Slc17a6 solute carrier family 17 member 6 increases expression ISO Haloperidol results in increased expression of SLC17A6 mRNA; Haloperidol results in increased expression of SLC17A6 protein CTD PMID:18155072 NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542
JBrowse link
G Slc17a8 solute carrier family 17 member 8 affects response to substance ISO SLC17A8 protein affects the susceptibility to Haloperidol CTD PMID:18278042 NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079
JBrowse link
G Slc18a2 solute carrier family 18 member A2 affects binding ISO Haloperidol binds to SLC18A2 protein CTD PMID:7912402 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
JBrowse link
G Slc1a1 solute carrier family 1 member 1 decreases expression EXP Haloperidol results in decreased expression of SLC1A1 mRNA CTD PMID:12873733 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402
JBrowse link
G Slc1a2 solute carrier family 1 member 2 decreases expression EXP Haloperidol results in decreased expression of SLC1A2 mRNA CTD PMID:12873733 NCBI chr 3:89,005,129...89,126,498
Ensembl chr 3:89,005,129...89,126,498
JBrowse link
G Slc1a3 solute carrier family 1 member 3 decreases expression EXP Haloperidol results in decreased expression of SLC1A3 mRNA CTD PMID:15860345 NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Haloperidol inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc25a3 solute carrier family 25 member 3 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SLC25A3 protein CTD PMID:34122009 NCBI chr 7:25,611,937...25,619,401
Ensembl chr 7:25,586,725...25,667,727
JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO Haloperidol results in increased expression of SLC2A4 mRNA CTD PMID:16002093 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc39a7 solute carrier family 39 member 7 increases expression ISO Haloperidol results in increased expression of SLC39A7 mRNA CTD PMID:14647396 NCBI chr20:4,823,166...4,826,538
Ensembl chr20:4,822,012...4,826,537
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions
increases expression
ISO
EXP
SLC6A3 protein promotes the reaction [Haloperidol results in increased expression of NTS mRNA]
Haloperidol results in increased expression of SLC6A3 protein
CTD PMID:14698760 PMID:17069804 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Slc6a4 solute carrier family 6 member 4 increases expression EXP Haloperidol results in increased expression of SLC6A4 CTD PMID:12007678 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
G Snap25 synaptosome associated protein 25 affects response to substance
affects expression
ISO
EXP
SNAP25 gene SNP affects the susceptibility to Haloperidol
Haloperidol affects the expression of SNAP25 mRNA
CTD PMID:15823421 PMID:15860345 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760
JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide increases expression ISO Haloperidol results in increased expression of SNRPD2 mRNA CTD PMID:14647396 NCBI chr 1:78,798,377...78,801,227
Ensembl chr 1:78,798,377...78,803,351
JBrowse link
G Sod1 superoxide dismutase 1 increases expression
multiple interactions
decreases expression
EXP Haloperidol results in increased expression of SOD1 mRNA
Clozapine inhibits the reaction [Haloperidol results in decreased expression of SOD1 protein]; Haloperidol results in decreased activity of and results in decreased expression of SOD1 protein; olanzapine inhibits the reaction [Haloperidol results in decreased expression of SOD1 protein]; Risperidone inhibits the reaction [Haloperidol results in decreased expression of SOD1 protein]
CTD PMID:12482469 PMID:12752374 PMID:16564057 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression
multiple interactions
EXP Haloperidol results in decreased expression of SOD2 mRNA; Haloperidol results in decreased expression of SOD2 protein
Haloperidol results in decreased activity of and results in decreased expression of SOD2 protein
CTD PMID:12482469 PMID:15860345 PMID:16564057 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sod3 superoxide dismutase 3 increases expression EXP Haloperidol results in increased expression of SOD3 mRNA CTD PMID:15860345 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Speg striated muscle enriched protein kinase increases expression ISO Haloperidol results in increased expression of SPEG protein CTD PMID:34122009 NCBI chr 9:76,865,714...76,923,170
Ensembl chr 9:76,865,754...76,923,144
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO Haloperidol results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:17052361 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Srpra SRP receptor subunit alpha decreases expression ISO Haloperidol results in decreased expression of SRPRA protein CTD PMID:34122009 NCBI chr 8:33,560,365...33,566,458
Ensembl chr 8:33,560,348...33,566,470
JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SRSF2 protein CTD PMID:34122009 NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338
JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SRSF5 protein CTD PMID:34122009 NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177
JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression ISO Haloperidol results in decreased expression of STIP1 protein CTD PMID:34122009 NCBI chr 1:204,209,434...204,228,452
Ensembl chr 1:204,178,932...204,228,476
JBrowse link
G Strn4 striatin 4 increases expression ISO Haloperidol results in increased expression of STRN4 mRNA CTD PMID:14647396 NCBI chr 1:77,482,267...77,511,862
Ensembl chr 1:77,482,094...77,511,858
JBrowse link
G Stt3a STT3 oligosaccharyltransferase complex catalytic subunit A multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of STT3A protein CTD PMID:34122009 NCBI chr 8:36,443,623...36,483,111
Ensembl chr 8:36,446,788...36,483,293
JBrowse link
G Stx1a syntaxin 1A increases expression EXP Haloperidol results in increased expression of STX1A mRNA CTD PMID:15860345 NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930
JBrowse link
G Stx1b syntaxin 1B affects expression EXP Haloperidol affects the expression of STX1B mRNA CTD PMID:15860345 NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280
JBrowse link
G Stx4 syntaxin 4 increases expression EXP Haloperidol results in increased expression of STX4 mRNA CTD PMID:15860345 NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979
JBrowse link
G Stx5 syntaxin 5 decreases expression EXP Haloperidol results in decreased expression of STX5 mRNA CTD PMID:15860345 NCBI chr 1:205,637,401...205,653,563
Ensembl chr 1:205,637,413...205,653,563
JBrowse link
G Stx7 syntaxin 7 decreases expression EXP Haloperidol results in decreased expression of STX7 mRNA CTD PMID:15860345 NCBI chr 1:21,197,075...21,237,320
Ensembl chr 1:21,197,075...21,237,279
JBrowse link
G Stx8 syntaxin 8 affects expression EXP Haloperidol affects the expression of STX8 mRNA CTD PMID:15860345 NCBI chr10:52,655,643...52,900,048
Ensembl chr10:52,654,990...52,894,993
JBrowse link
G Supt3h SPT3 homolog, SAGA and STAGA complex component increases expression EXP Haloperidol results in increased expression of SUPT3H mRNA CTD PMID:16715494 NCBI chr 9:15,878,296...16,206,768
Ensembl chr 9:15,868,287...16,206,706
JBrowse link
G Syn2 synapsin II increases expression EXP Haloperidol results in increased expression of SYN2 mRNA CTD PMID:15860345 NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192
JBrowse link
G Sypl1 synaptophysin-like 1 decreases expression ISO Haloperidol results in decreased expression of SYPL mRNA CTD PMID:18797397 NCBI chr 6:49,565,111...49,585,205
Ensembl chr 6:49,565,154...49,585,330
JBrowse link
G Syt11 synaptotagmin 11 increases expression EXP Haloperidol results in increased expression of SYT11 mRNA CTD PMID:15860345 NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964
JBrowse link
G Syt3 synaptotagmin 3 decreases expression EXP Haloperidol results in decreased expression of SYT3 mRNA CTD PMID:15860345 NCBI chr 1:94,880,835...94,895,518
Ensembl chr 1:94,881,247...94,895,246
JBrowse link
G Syt4 synaptotagmin 4 affects expression EXP Haloperidol affects the expression of SYT4 mRNA CTD PMID:15860345 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332
JBrowse link
G Tac1 tachykinin, precursor 1 increases expression EXP Haloperidol results in increased expression of TAC1 mRNA CTD PMID:10974607 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Tagln transgelin decreases expression ISO Haloperidol results in decreased expression of TAGLN mRNA CTD PMID:17175557 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
JBrowse link
G Tagln2 transgelin 2 decreases expression ISO Haloperidol results in decreased expression of TAGLN2 protein CTD PMID:34122009 NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member decreases expression EXP Haloperidol results in decreased expression of TAP1 mRNA CTD PMID:16452686 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901
JBrowse link
G Tatdn1 TatD DNase domain containing 1 increases expression ISO Haloperidol results in increased expression of TATDN1 mRNA CTD PMID:14647396 NCBI chr 7:90,451,025...90,481,000
Ensembl chr 7:90,441,079...90,481,133
JBrowse link
G Tcaf1 TRPM8 channel-associated factor 1 decreases expression ISO Haloperidol results in decreased expression of TCAF1 protein CTD PMID:34122009 NCBI chr 4:71,589,674...71,639,309
Ensembl chr 4:71,591,200...71,613,309
JBrowse link
G Tcerg1 transcription elongation regulator 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of TCERG1 protein CTD PMID:34122009 NCBI chr18:34,505,708...34,566,470
Ensembl chr18:34,505,751...34,566,470
JBrowse link
G Tf transferrin decreases expression ISO Haloperidol results in decreased expression of TRF mRNA CTD PMID:17177202 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tgoln2 trans-golgi network protein 2 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of TGOLN2 protein CTD PMID:34122009 NCBI chr 4:104,663,356...104,671,208
Ensembl chr 4:104,663,353...104,671,164
JBrowse link
G Th tyrosine hydroxylase increases expression EXP Haloperidol results in increased expression of TH protein CTD PMID:17028028 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Thra thyroid hormone receptor alpha decreases expression
increases expression
EXP Haloperidol results in decreased expression of THRA mRNA alternative form
Haloperidol results in increased expression of THRA mRNA alternative form
CTD PMID:11564422 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Tln2 talin 2 decreases expression ISO Haloperidol results in decreased expression of TLN2 protein CTD PMID:34122009 NCBI chr 8:67,830,920...68,252,223
Ensembl chr 8:67,834,326...68,252,219
JBrowse link
G Tm9sf2 transmembrane 9 superfamily member 2 decreases expression ISO Haloperidol results in decreased expression of TM9SF2 protein CTD PMID:34122009 NCBI chr15:99,201,556...99,254,054
Ensembl chr15:99,201,489...99,254,049
JBrowse link
G Tmem109 transmembrane protein 109 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of TMEM109 protein CTD PMID:34122009 NCBI chr 1:207,519,628...207,530,245
Ensembl chr 1:207,519,624...207,530,215
JBrowse link
G Tmod3 tropomodulin 3 decreases expression ISO Haloperidol results in decreased expression of TMOD3 protein CTD PMID:34122009 NCBI chr 8:76,248,978...76,310,855
Ensembl chr 8:76,248,979...76,310,977
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP
ISO
Haloperidol affects the reaction [Phencyclidine affects the expression of TNF mRNA]
Haloperidol results in increased expression of TNF protein
Haloperidol results in increased expression of TNF mRNA
Cannabidiol inhibits the reaction [Haloperidol results in increased expression of TNF mRNA]
CTD PMID:16478754 PMID:18554768 PMID:18590723 PMID:30217539 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnik TRAF2 and NCK interacting kinase decreases expression ISO Haloperidol results in decreased expression of TNIK mRNA CTD PMID:14647396 NCBI chr 2:111,184,352...111,587,993
Ensembl chr 2:111,184,387...111,580,750
JBrowse link
G Tor1a torsin family 1, member A affects response to substance ISO TOR1A gene mutant form affects the susceptibility to Haloperidol CTD PMID:20227500 NCBI chr 3:14,250,667...14,257,704
Ensembl chr 3:14,250,676...14,257,691
JBrowse link
G Tp53 tumor protein p53 increases expression EXP Haloperidol results in increased expression of TP53 mRNA; Haloperidol results in increased expression of TP53 protein CTD PMID:16462815 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression EXP Haloperidol results in increased expression of TPI1 mRNA CTD PMID:15860345 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
G Trim2 tripartite motif-containing 2 decreases expression ISO Haloperidol results in decreased expression of TRIM2 mRNA CTD PMID:14647396 NCBI chr 2:169,500,628...169,652,855
Ensembl chr 2:169,500,634...169,652,927
JBrowse link
G Trim23 tripartite motif-containing 23 decreases expression EXP Haloperidol results in decreased expression of TRIM23 mRNA CTD PMID:15860345 NCBI chr 2:35,302,405...35,335,746
En