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ONTOLOGY REPORT - ANNOTATIONS


Term:estazolam
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Accession:CHEBI:4858 term browser browse the term
Definition:A triazolo[4,3-a][1,4]benzodiazepine having a phenyl group at position 6 and a chloro substituent at position 8. A short-acting benzodiazepine with general properties similar to diazepam, it is given by mouth as a hypnotic in the short-term management of insomnia.
Synonyms:exact_synonym: 8-chloro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
 related_synonym: 8-chloro-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine;   Formula=C16H11ClN4;   InChI=1S/C16H11ClN4/c17-12-6-7-14-13(8-12)16(11-4-2-1-3-5-11)18-9-15-20-19-10-21(14)15/h1-8,10H,9H2;   InChIKey=CDCHDCWJMGXXRH-UHFFFAOYSA-N;   SMILES=Clc1ccc-2c(c1)C(=NCc1nncn-21)c1ccccc1;   estazolamum
 alt_id: CHEBI:149847
 xref: Beilstein:1220868;   CAS:29975-16-4;   DrugBank:DB01215;   Drug_Central:1056;   KEGG:D00311
 xref_mesh: MESH:D004949
 xref: PMID:7154007;   Patent:DE1955349;   Patent:DE2012190;   Patent:DE2114441;   Patent:US3701782;   Wikipedia:Estazolam


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estazolam term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:6480464
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:6480464
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 JBrowse link 12 18,679,809 18,709,397 RGD:6480464
G Trh thyrotropin releasing hormone JBrowse link 4 124,110,716 124,113,242 RGD:6480464
G Trhr thyrotropin releasing hormone receptor JBrowse link 7 83,113,641 83,153,520 RGD:6480464

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  CHEBI ontology 19770
    role 19717
      biological role 19716
        biophysical role 12284
          membrane transport modulator 12065
            GABA modulator 4658
              estazolam 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19655
                    p-block element atom 19655
                      carbon group element atom 19548
                        carbon atom 19537
                          organic molecular entity 19537
                            organic molecule 19461
                              organic cyclic compound 19222
                                organic heterocyclic compound 18339
                                  heteroarene 15845
                                    monocyclic heteroarene 13200
                                      azole 12347
                                        triazoles 3612
                                          estazolam 4
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