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ONTOLOGY REPORT - ANNOTATIONS


Term:phenylbutazone
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Accession:CHEBI:48574 term browser browse the term
Definition:A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
Synonyms:related_synonym: 3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine;   4-BUTYL-1,2-DIPHENYL-PYRAZOLIDINE-3,5-DIONE;   4-butyl-1,2-diphenylpyrazolidine-3,5-dione;   4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedione;   Formula=C19H20N2O2;   InChI=1S/C19H20N2O2/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16/h4-13,17H,2-3,14H2,1H3;   InChIKey=VYMDGNCVAMGZFE-UHFFFAOYSA-N;   Phenbutazone;   Phenylbutazon;   SMILES=CCCCC1C(=O)N(N(C1=O)c1ccccc1)c1ccccc1;   fenilbutazona;   phenylbutazonum
 alt_id: CHEBI:44635;   CHEBI:8091
 xref: Beilstein:290080 "Beilstein";   CAS:50-33-9 "KEGG COMPOUND";   DrugBank:DB00812;   Drug_Central:2145 "DrugCentral";   HMDB:HMDB0014950;   KEGG:C07440;   KEGG:D00510;   LINCS:LSM-2219
 xref_mesh: MESH:D010653
 xref: PDBeChem:P1Z;   PMID:11264893 "Europe PMC";   PMID:12692637 "Europe PMC";   PMID:13010905 "Europe PMC";   PMID:13048452 "Europe PMC";   PMID:13747451 "Europe PMC";   PMID:19614844 "Europe PMC";   PMID:20176071 "Europe PMC";   PMID:21668837 "Europe PMC";   PMID:22082440 "Europe PMC";   PMID:22180948 "Europe PMC";   PMID:22245664 "Europe PMC";   PMID:23369749 "Europe PMC";   PMID:23525812 "Europe PMC";   PMID:25287371 "Europe PMC";   PMID:26090772 "Europe PMC";   PMID:26808199 "Europe PMC";   PMID:3425858 "Europe PMC";   PMID:7655439 "Europe PMC";   Reaxys:290080 "Reaxys";   VSDB:1775;   Wikipedia:Phenylbutazone


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phenylbutazone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcat1 branched chain amino acid transaminase 1 JBrowse link 4 179,259,305 179,340,021 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Chuk component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 1 263,848,829 263,884,354 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Havcr1 hepatitis A virus cellular receptor 1 JBrowse link 10 31,813,819 31,860,934 RGD:6480464
G Krt14 keratin 14 JBrowse link 10 88,118,029 88,122,233 RGD:6480464
G Lmcd1 LIM and cysteine-rich domains 1 JBrowse link 4 144,192,989 144,252,554 RGD:6480464
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6480464
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6480464
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Rnd1 Rho family GTPase 1 JBrowse link 7 140,349,138 140,356,209 RGD:6480464
G Sell selectin L JBrowse link 13 82,369,820 82,387,774 RGD:6480464
G Slc22a12 solute carrier family 22 member 12 JBrowse link 1 221,910,787 221,919,277 RGD:6480464
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 9 95,295,701 95,302,822 RGD:6480464
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 JBrowse link 9 95,285,592 95,302,822 RGD:6480464
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 JBrowse link 9 95,221,474 95,302,822 RGD:6480464
oxyphenbutazone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        biochemical role 19178
          metabolite 19150
            phenylbutazone 20
              kebuzone 0
              oxyphenbutazone + 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic molecule 19417
                              organic cyclic compound 19184
                                organic heterocyclic compound 18262
                                  organic heteromonocyclic compound 16347
                                    diazolidine 565
                                      pyrazolidines 28
                                        phenylbutazone 20
                                          kebuzone 0
                                          oxyphenbutazone + 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.