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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dopaminergic antagonist
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Accession:CHEBI:48561 term browser browse the term
Definition:A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
Synonyms:related_synonym: dopamine antagonist;   dopamine blocker;   dopamine receptor antagonist;   dopaminergic antagonists



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(+)-butaclamol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 affects binding ISO Butaclamol binds to DRD2 protein CTD PMID:18457824 NCBI chr 9:49,251,633...49,319,477
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
G Drd3 dopamine receptor D3 multiple interactions ISO Butaclamol inhibits the reaction [Dopamine results in increased activity of DRD3 protein] CTD PMID:31323226 NCBI chr16:43,574,285...43,646,353
Ensembl chr16:43,574,389...43,643,295
JBrowse link
G Drd4 dopamine receptor D4 affects binding ISO Butaclamol binds to Drd4 protein RGD PMID:8078498 RGD:7248459 NCBI chr 7:140,871,887...140,876,377
Ensembl chr 7:140,871,919...140,876,377
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO Butaclamol results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
(1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 multiple interactions ISO 5-methoxy-1-methyl-2-(n-propylamino)tetralin binds to and results in decreased activity of DRD2 protein CTD PMID:10728880 NCBI chr 9:49,251,633...49,319,477
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
G Drd3 dopamine receptor D3 multiple interactions ISO 5-methoxy-1-methyl-2-(n-propylamino)tetralin binds to and results in decreased activity of DRD3 protein CTD PMID:10728880 NCBI chr16:43,574,285...43,646,353
Ensembl chr16:43,574,389...43,643,295
JBrowse link
(Z)-chlorprothixene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine (serotonin) receptor 1A multiple interactions ISO Chlorprothixene inhibits the reaction [(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane binds to HTR1A protein] CTD PMID:2891550 NCBI chr13:105,580,201...105,584,641
Ensembl chr13:105,580,147...105,584,630
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO Chlorprothixene results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
G Prl prolactin increases secretion ISO Chlorprothixene results in increased secretion of PRL protein CTD PMID:10525070 NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188
JBrowse link
amoxapine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd1 dopamine receptor D1 affects binding EXP Amoxapine binds to DRD1 protein CTD PMID:11180191 NCBI chr13:54,205,202...54,209,677
Ensembl chr13:54,205,202...54,209,724
JBrowse link
G Drd2 dopamine receptor D2 affects binding EXP Amoxapine binds to DRD2 protein CTD PMID:11180191 NCBI chr 9:49,251,633...49,319,477
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 multiple interactions EXP Amoxapine results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA]; Amoxapine results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA] CTD PMID:22164246 NCBI chr 2:55,301,814...55,488,157
Ensembl chr 2:55,325,982...55,488,157
JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 multiple interactions EXP Amoxapine results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA] CTD PMID:22164246 NCBI chr 9:32,226,002...32,255,687
Ensembl chr 9:32,226,003...32,255,646
JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 multiple interactions EXP Amoxapine results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA] CTD PMID:22164246 NCBI chr16:94,545,839...94,798,719
Ensembl chr16:94,549,495...94,798,560
JBrowse link
G Prl prolactin increases expression ISO Amoxapine results in increased expression of PRL protein CTD PMID:6363397 NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188
JBrowse link
G Tac1 tachykinin 1 decreases expression ISO Amoxapine results in decreased expression of TAC1 protein CTD PMID:8955926 NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834
JBrowse link
asenapine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
decreases expression
ISO Asenapine results in decreased activity of CYP1A2 protein
Asenapine results in decreased expression of CYP1A2 mRNA
CTD PMID:32941854 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
azaperone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO Azaperone results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
chlorpromazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 multiple interactions
decreases expression
ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of ABCB11 mRNA
Chlorpromazine results in decreased expression of ABCB11 mRNA
CTD PMID:27344345 PMID:27765674 PMID:28391356 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,960
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A increases expression
decreases activity
ISO Chlorpromazine analog results in increased expression of ABCB1 mRNA
Chlorpromazine results in decreased activity of ABCB1 protein
CTD PMID:15924885 PMID:16810505 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcb1b ATP-binding cassette, sub-family B (MDR/TAP), member 1B affects activity ISO Chlorpromazine affects the activity of ABCB1B protein CTD PMID:12626638 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315
JBrowse link
G Abcb4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of ABCB4 mRNA CTD PMID:27344345 NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231
JBrowse link
G Abcb6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 decreases expression ISO Chlorpromazine results in decreased expression of ABCB6 mRNA CTD PMID:25596134 NCBI chr 1:75,148,284...75,157,066
Ensembl chr 1:75,148,361...75,157,036
JBrowse link
G Abcb9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 increases expression ISO Chlorpromazine results in increased expression of ABCB9 mRNA CTD PMID:25596134 NCBI chr 5:124,199,920...124,234,009
Ensembl chr 5:124,199,593...124,233,861
JBrowse link
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 increases expression ISO Chlorpromazine results in increased expression of ABCC2 mRNA CTD PMID:27765674 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Abcc3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 increases expression
decreases expression
ISO Chlorpromazine analog results in increased expression of ABCC3 mRNA
Chlorpromazine results in decreased expression of ABCC3 mRNA
CTD PMID:15924885 PMID:25596134 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) multiple interactions ISO Chlorpromazine inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone] CTD PMID:18834354 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of ABCG8 mRNA CTD PMID:27344345 NCBI chr17:84,983,730...85,007,761
Ensembl chr17:84,983,730...85,007,761
JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha decreases phosphorylation ISO Chlorpromazine results in decreased phosphorylation of ACACA protein CTD PMID:17512020 NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477
JBrowse link
G Ace2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 decreases expression ISO Chlorpromazine results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416
JBrowse link
G Ache acetylcholinesterase decreases activity
increases activity
multiple interactions
ISO
EXP
Chlorpromazine results in decreased activity of ACHE protein
Chlorpromazine results in increased activity of ACHE protein
Dichlorvos promotes the reaction [Chlorpromazine results in decreased activity of ACHE protein]
CTD PMID:4859365 PMID:29614332 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions EXP Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA] CTD PMID:21869564 NCBI chr 9:22,038,023...22,047,042
Ensembl chr 9:22,038,023...22,047,007
JBrowse link
G Adra1a adrenergic receptor, alpha 1a decreases activity ISO Chlorpromazine results in decreased activity of ADRA1A protein CTD PMID:23611293 NCBI chr14:66,872,700...67,008,689
Ensembl chr14:66,872,700...67,008,617
JBrowse link
G Adra1b adrenergic receptor, alpha 1b decreases activity ISO Chlorpromazine results in decreased activity of ADRA1B protein CTD PMID:23611293 NCBI chr11:43,665,432...43,792,076
Ensembl chr11:43,665,433...43,792,037
JBrowse link
G Afp alpha fetoprotein decreases expression ISO Chlorpromazine analog results in decreased expression of AFP mRNA CTD PMID:15924885 NCBI chr 5:90,638,573...90,656,766
Ensembl chr 5:90,638,596...90,656,766
JBrowse link
G Agrn agrin decreases expression ISO Chlorpromazine results in decreased expression of AGRN mRNA CTD PMID:25596134 NCBI chr 4:156,249,747...156,281,997
Ensembl chr 4:156,249,747...156,281,945
JBrowse link
G Ahr aryl-hydrocarbon receptor affects activity ISO Chlorpromazine affects the activity of AHR protein CTD PMID:25596134 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Ak3 adenylate kinase 3 decreases expression ISO Chlorpromazine results in decreased expression of AK3 mRNA CTD PMID:25596134 NCBI chr19:28,968,715...29,026,122
Ensembl chr19:28,998,233...29,025,361
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 decreases phosphorylation ISO Chlorpromazine results in decreased phosphorylation of AKT1 protein CTD PMID:17512020 NCBI chr12:112,620,255...112,641,318
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of ALDH1A1 mRNA CTD PMID:27344345 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829
JBrowse link
G Aldoa aldolase A, fructose-bisphosphate increases expression ISO Chlorpromazine results in increased expression of ALDOA mRNA CTD PMID:25596134 NCBI chr 7:126,394,406...126,400,166
Ensembl chr 7:126,394,406...126,399,923
Ensembl chr 7:126,394,406...126,399,923
JBrowse link
G Ap1s1 adaptor protein complex AP-1, sigma 1 decreases expression ISO Chlorpromazine results in decreased expression of AP1S1 mRNA CTD PMID:17175557 NCBI chr 5:137,063,847...137,074,962
Ensembl chr 5:137,063,847...137,074,989
JBrowse link
G Apoc4 apolipoprotein C-IV multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of APOC4 mRNA CTD PMID:27344345 NCBI chr 7:19,412,009...19,415,385
Ensembl chr 7:19,412,008...19,415,404
JBrowse link
G Apof apolipoprotein F multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of APOF mRNA CTD PMID:27344345 NCBI chr10:128,104,568...128,107,119
Ensembl chr10:128,103,866...128,106,022
JBrowse link
G Areg amphiregulin decreases expression ISO Chlorpromazine results in decreased expression of AREG mRNA CTD PMID:15924885 PMID:30703373 NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291
JBrowse link
G Arfgef2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) increases expression ISO Chlorpromazine results in increased expression of ARFGEF2 mRNA CTD PMID:25596134 NCBI chr 2:166,647,371...166,739,972
Ensembl chr 2:166,647,508...166,739,972
JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor (GEF) 10 decreases expression ISO Chlorpromazine results in decreased expression of ARHGEF10 mRNA CTD PMID:25596134 NCBI chr 8:14,956,405...15,051,085
Ensembl chr 8:14,961,663...15,051,085
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 increases expression ISO Chlorpromazine results in increased expression of ASAH1 mRNA CTD PMID:17175557 NCBI chr 8:41,793,683...41,850,681
Ensembl chr 8:41,793,234...41,827,810
JBrowse link
G Asns asparagine synthetase increases expression ISO Chlorpromazine results in increased expression of ASNS mRNA CTD PMID:17175557 NCBI chr 6:7,675,165...7,693,209
Ensembl chr 6:7,675,169...7,693,254
JBrowse link
G Atf4 activating transcription factor 4 affects activity
multiple interactions
ISO Chlorpromazine affects the activity of ATF4 protein
[Chlorpromazine co-treated with Cholic Acids] affects the expression of ATF4 mRNA
CTD PMID:25596134 PMID:27344345 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742
JBrowse link
G Atp6v1b2 ATPase, H+ transporting, lysosomal V1 subunit B2 decreases expression ISO Chlorpromazine results in decreased expression of ATP6V1B2 protein CTD PMID:19441803 NCBI chr 8:69,541,388...69,566,370
Ensembl chr 8:69,541,298...69,566,363
JBrowse link
G Avp arginine vasopressin increases expression
multiple interactions
ISO Chlorpromazine results in increased expression of AVP protein
Chlorpromazine inhibits the reaction [Lithium results in increased expression of AVP protein]
CTD PMID:3567260 PMID:3976404 NCBI chr 2:130,422,540...130,424,508
Ensembl chr 2:130,422,540...130,424,474
JBrowse link
G Bag4 BCL2-associated athanogene 4 decreases expression ISO Chlorpromazine analog results in decreased expression of BAG4 mRNA CTD PMID:15924885 NCBI chr 8:26,254,566...26,275,237
Ensembl chr 8:26,254,566...26,275,315
JBrowse link
G Bcl2l1 BCL2-like 1 increases expression EXP Chlorpromazine results in increased expression of BCL2L1 mRNA CTD PMID:21683644 NCBI chr 2:152,600,652...152,675,723
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Bdnf brain derived neurotrophic factor affects response to substance
affects expression
ISO BDNF affects the susceptibility to Chlorpromazine
Chlorpromazine affects the expression of BDNF mRNA
CTD PMID:18408624 PMID:31324950 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO Chlorpromazine analog results in increased expression of BHLHE40 mRNA CTD PMID:15924885 NCBI chr 6:108,637,590...108,643,886
Ensembl chr 6:108,637,590...108,643,886
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO Chlorpromazine results in decreased expression of BIRC2 mRNA CTD PMID:30703373 NCBI chr 9:7,818,227...7,837,123
Ensembl chr 9:7,818,228...7,837,065
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO Chlorpromazine analog results in decreased expression of BIRC5 mRNA; Chlorpromazine results in decreased expression of BIRC5 mRNA CTD PMID:15924885 PMID:30703373 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569
JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 increases expression ISO Chlorpromazine results in increased expression of BNIP3 mRNA CTD PMID:25596134 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Chlorpromazine analog results in increased expression of BTG2 mRNA CTD PMID:15924885 NCBI chr 1:134,002,603...134,006,893
Ensembl chr 1:134,002,908...134,006,858
JBrowse link
G Btg3 BTG anti-proliferation factor 3 increases expression ISO Chlorpromazine analog results in increased expression of BTG3 mRNA CTD PMID:15924885 NCBI chr16:78,156,748...78,174,069
Ensembl chr16:78,129,525...78,174,080
JBrowse link
G C3 complement component 3 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of C3 mRNA CTD PMID:27344345 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136
JBrowse link
G C6 complement component 6 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of C6 mRNA CTD PMID:27344345 NCBI chr15:4,756,550...4,833,527
Ensembl chr15:4,756,657...4,844,449
JBrowse link
G Calcr calcitonin receptor multiple interactions EXP Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of CALCR mRNA] CTD PMID:21869564 NCBI chr 6:3,685,678...3,764,713
Ensembl chr 6:3,685,680...3,764,714
JBrowse link
G Calr calreticulin decreases expression ISO Chlorpromazine results in decreased expression of CALR mRNA CTD PMID:18246545 NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563
JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions EXP Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of CAR2 mRNA] CTD PMID:21869564 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830
JBrowse link
G Cat catalase multiple interactions
decreases expression
decreases activity
ISO carvedilol inhibits the reaction [Chlorpromazine results in decreased expression of CAT protein]; zolpidem inhibits the reaction [Chlorpromazine results in decreased activity of CAT] CTD PMID:12010767 PMID:17513028 PMID:25449126 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO Chlorpromazine results in decreased expression of CCN2 mRNA; Chlorpromazine results in decreased expression of CCN2 protein CTD PMID:30703373 NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581
JBrowse link
G Ccn3 cellular communication network factor 3 affects expression ISO Chlorpromazine affects the expression of CCN3 mRNA CTD PMID:31324950 NCBI chr15:54,609,306...54,617,158
Ensembl chr15:54,609,098...54,617,435
JBrowse link
G Ccnb2 cyclin B2 decreases expression ISO Chlorpromazine analog results in decreased expression of CCNB2 mRNA; Chlorpromazine results in decreased expression of CCNB2 mRNA CTD PMID:15924885 NCBI chr 9:70,314,971...70,328,836
Ensembl chr 9:70,314,974...70,328,829
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Chlorpromazine results in decreased expression of CCND1 mRNA CTD PMID:17202759 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO Chlorpromazine analog results in decreased expression of CCND3 mRNA CTD PMID:15924885 NCBI chr17:47,815,976...47,910,614
Ensembl chr17:47,815,976...47,910,616
JBrowse link
G Ccnf cyclin F decreases expression ISO Chlorpromazine analog results in decreased expression of CCNF mRNA CTD PMID:15924885 NCBI chr17:24,442,204...24,470,383
Ensembl chr17:24,441,172...24,470,458
JBrowse link
G Cd274 CD274 antigen multiple interactions ISO Chlorpromazine inhibits the reaction [platycodin D results in decreased expression of and results in increased secretion of CD274 protein] CTD PMID:31150782 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495
JBrowse link
G Cd44 CD44 antigen multiple interactions
decreases expression
EXP
ISO
Chlorpromazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein]
Chlorpromazine results in decreased expression of CD44 protein
CTD PMID:9929743 PMID:30703373 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
JBrowse link
G Cd86 CD86 antigen increases expression ISO Chlorpromazine results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443
JBrowse link
G Cdk5 cyclin-dependent kinase 5 decreases expression ISO Chlorpromazine analog results in decreased expression of CDK5 mRNA CTD PMID:15924885 NCBI chr 5:24,612,595...24,628,737
Ensembl chr 5:24,623,239...24,628,528
JBrowse link
G Cdk7 cyclin-dependent kinase 7 increases expression ISO Chlorpromazine analog results in increased expression of CDK7 mRNA CTD PMID:15924885 NCBI chr13:100,833,532...100,867,450
Ensembl chr13:100,839,139...100,867,447
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) multiple interactions
increases expression
ISO [EGR1 binds to CDKN1A promoter] promotes the reaction [Chlorpromazine results in increased expression of CDKN1A mRNA]; EGR1 promotes the reaction [Chlorpromazine results in increased expression of CDKN1A mRNA] CTD PMID:20368687 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cdkn2c cyclin dependent kinase inhibitor 2C decreases expression ISO Chlorpromazine analog results in decreased expression of CDKN2C mRNA CTD PMID:15924885 NCBI chr 4:109,518,073...109,523,953
Ensembl chr 4:109,518,073...109,524,386
JBrowse link
G Ces2h carboxylesterase 2H multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of CES2 mRNA CTD PMID:27344345 NCBI chr 8:105,727,462...105,747,042
Ensembl chr 8:105,727,485...105,747,810
JBrowse link
G Cfh complement component factor h multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of CFH mRNA CTD PMID:27344345 NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 decreases expression ISO Chlorpromazine results in decreased expression of CGREF1 mRNA CTD PMID:17202759 NCBI chr 5:31,090,487...31,102,824
Ensembl chr 5:31,090,487...31,102,935
JBrowse link
G Chtf18 CTF18, chromosome transmission fidelity factor 18 decreases expression ISO Chlorpromazine analog results in decreased expression of CHTF18 mRNA CTD PMID:15924885 NCBI chr17:25,938,004...25,946,409
Ensembl chr17:25,937,900...25,946,393
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 decreases expression ISO Chlorpromazine results in decreased expression of CITED2 mRNA CTD PMID:18246545 NCBI chr10:17,598,452...17,601,422
Ensembl chr10:17,598,966...17,601,422
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression ISO Chlorpromazine analog results in decreased expression of CKS2 mRNA CTD PMID:15924885 NCBI chr13:51,799,268...51,804,698
Ensembl chr13:51,799,268...51,804,696
JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 increases expression EXP Chlorpromazine results in increased expression of CLCF1 mRNA CTD PMID:21683644 NCBI chr19:4,264,292...4,273,559
Ensembl chr19:4,264,292...4,273,544
JBrowse link
G Col18a1 collagen, type XVIII, alpha 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of COL18A1 mRNA CTD PMID:27344345 NCBI chr10:76,888,013...77,002,391
Ensembl chr10:76,888,012...77,002,382
JBrowse link
G Col4a1 collagen, type IV, alpha 1 decreases expression ISO Chlorpromazine results in decreased expression of COL4A1 mRNA CTD PMID:25596134 NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826
JBrowse link
G Cort cortistatin affects expression ISO Chlorpromazine affects the expression of CORT mRNA CTD PMID:31324950 NCBI chr 4:149,209,491...149,211,220
Ensembl chr 4:149,209,491...149,211,220
JBrowse link
G Cox8a cytochrome c oxidase subunit 8A affects expression
increases expression
ISO Chlorpromazine affects the expression of COX8A mRNA
Chlorpromazine results in increased expression of COX8A mRNA
CTD PMID:18246545 NCBI chr19:7,192,523...7,194,981
Ensembl chr19:7,192,518...7,194,981
JBrowse link
G Crh corticotropin releasing hormone decreases expression ISO Chlorpromazine results in decreased expression of CRH mRNA CTD PMID:16205782 NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560
JBrowse link
G Cth cystathionase (cystathionine gamma-lyase) decreases expression ISO Chlorpromazine results in decreased expression of CTH mRNA CTD PMID:25596134 NCBI chr 3:157,599,885...157,630,718
Ensembl chr 3:157,599,885...157,630,714
JBrowse link
G Ctsk cathepsin K multiple interactions EXP Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA] CTD PMID:21869564 NCBI chr 3:95,406,521...95,416,698
Ensembl chr 3:95,406,567...95,416,673
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 increases expression
multiple interactions
ISO Chlorpromazine results in increased expression of CXCL8 mRNA
[Chlorpromazine co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA
CTD PMID:29594315 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases activity
decreases response to substance
increases expression
ISO [Filipin co-treated with Chlorpromazine co-treated with Wortmannin] inhibits the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA]; Chlorpromazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
Chlorpromazine results in decreased activity of CYP1A1 protein
CYP1A1 protein results in decreased susceptibility to Chlorpromazine
Chlorpromazine results in increased expression of CYP1A1 mRNA
CTD PMID:17202759 PMID:18246545 PMID:18493746 PMID:25596134 PMID:26477383 More... NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
decreases response to substance
increases expression
increases oxidation
affects expression
decreases methylation
ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of CYP1A2 mRNA; [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Chlorpromazine; Chlorpromazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; CYP1A2 protein results in increased metabolism of and results in increased activity of Chlorpromazine
CYP1A2 protein results in decreased susceptibility to Chlorpromazine
Chlorpromazine results in increased expression of CYP1A2 mRNA
CYP1A2 protein results in increased oxidation of Chlorpromazine
Chlorpromazine affects the expression of CYP1A2 mRNA
CYP1A2 protein results in decreased methylation of Chlorpromazine
CTD PMID:18246545 PMID:18493746 PMID:19482014 PMID:20615392 PMID:23397584 More... NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases response to substance
decreases activity
multiple interactions
ISO CYP1B1 protein results in decreased susceptibility to Chlorpromazine
Chlorpromazine results in decreased activity of CYP1B1 protein
[Filipin co-treated with Chlorpromazine co-treated with Wortmannin] inhibits the reaction [Particulate Matter results in increased expression of CYP1B1 mRNA]
CTD PMID:26477383 PMID:29724254 PMID:33814510 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 decreases activity
decreases response to substance
ISO Chlorpromazine results in decreased activity of CYP2A6 protein
CYP2A6 protein results in decreased susceptibility to Chlorpromazine
CTD PMID:15135088 PMID:26477383 NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 multiple interactions
decreases response to substance
EXP
ISO
NR1I3 protein affects the reaction [Chlorpromazine results in increased expression of CYP2B10 mRNA]
CYP2B6 protein results in decreased susceptibility to Chlorpromazine
[Chlorpromazine results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; Chlorpromazine inhibits the reaction [Androstenols inhibits the reaction [NR1I3 protein results in increased expression of CYP2B6 mRNA]]
CTD PMID:10037683 PMID:12049174 PMID:17041008 PMID:26477383 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 decreases response to substance ISO CYP2C8 protein results in decreased susceptibility to Chlorpromazine CTD PMID:26477383 NCBI chr19:39,275,488...39,319,157
Ensembl chr19:39,257,849...39,319,157
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 decreases activity
decreases response to substance
affects methylation
multiple interactions
ISO Chlorpromazine results in decreased activity of CYP2C19 protein
CYP2C19 protein results in decreased susceptibility to Chlorpromazine
CYP2C19 protein affects the methylation of Chlorpromazine
[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Chlorpromazine
CTD PMID:15135088 PMID:20615392 PMID:23397584 PMID:26477383 NCBI chr19:39,378,000...39,451,547
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene decreases expression ISO Chlorpromazine results in decreased expression of CYP2C mRNA; Chlorpromazine results in decreased expression of CYP2C11 mRNA CTD PMID:18246545 NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733
JBrowse link
G Cyp2c55 cytochrome P450, family 2, subfamily c, polypeptide 55 decreases response to substance ISO CYP2C18 protein results in decreased susceptibility to Chlorpromazine CTD PMID:26477383 NCBI chr19:38,995,384...39,031,134
Ensembl chr19:38,995,463...39,031,137
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 decreases activity
multiple interactions
decreases response to substance
ISO Chlorpromazine results in decreased activity of CYP2C9 protein
[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Chlorpromazine
CYP2C9 protein results in decreased susceptibility to Chlorpromazine
CTD PMID:15135088 PMID:23397584 PMID:26477383 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 decreases activity
multiple interactions
decreases response to substance
ISO Chlorpromazine results in decreased activity of CYP2C9 protein
[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Chlorpromazine
CYP2C9 protein results in decreased susceptibility to Chlorpromazine
CTD PMID:15135088 PMID:23397584 PMID:26477383 NCBI chr19:39,102,342...39,175,200
Ensembl chr19:39,102,342...39,175,516
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 multiple interactions
decreases response to substance
ISO [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Chlorpromazine; CYP2D6 protein results in increased metabolism of and results in increased activity of Chlorpromazine
CYP2D6 protein results in decreased susceptibility to Chlorpromazine
CTD PMID:19482014 PMID:23397584 PMID:26477383 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity
decreases response to substance
ISO Chlorpromazine results in decreased activity of CYP2E1 protein
CYP2E1 protein results in decreased susceptibility to Chlorpromazine
CTD PMID:15135088 PMID:26477383 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 multiple interactions
decreases response to substance
EXP
ISO
NR1I3 protein affects the reaction [Chlorpromazine results in increased expression of CYP3A11 mRNA]
CYP3A5 protein results in decreased susceptibility to Chlorpromazine
CTD PMID:12049174 PMID:26477383 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774
JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 decreases response to substance ISO CYP3A7 protein results in decreased susceptibility to Chlorpromazine CTD PMID:26477383 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
JBrowse link
G Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of CYP8B1 mRNA CTD PMID:27344345 NCBI chr 9:121,743,422...121,745,371
Ensembl chr 9:121,743,422...121,745,371
JBrowse link
G Dao D-amino acid oxidase decreases activity ISO Chlorpromazine results in decreased activity of DAO protein CTD PMID:18615285 NCBI chr 5:114,137,696...114,163,736
Ensembl chr 5:114,141,764...114,163,743
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein multiple interactions EXP Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of DCSTAMP mRNA] CTD PMID:21869564 NCBI chr15:39,609,326...39,624,334
Ensembl chr15:39,609,326...39,624,334
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Chlorpromazine results in increased expression of DDIT3 mRNA CTD PMID:25596134 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Depp1 DEPP1 autophagy regulator increases expression ISO Chlorpromazine results in increased expression of DEPP1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 6:116,627,645...116,629,808
Ensembl chr 6:116,627,570...116,629,755
JBrowse link
G Drd1 dopamine receptor D1 decreases activity ISO Chlorpromazine results in decreased activity of DRD1 protein CTD PMID:23611293 NCBI chr13:54,205,202...54,209,677
Ensembl chr13:54,205,202...54,209,724
JBrowse link
G Drd2 dopamine receptor D2 decreases response to substance
decreases activity
ISO DRD2 polymorphism results in decreased susceptibility to Chlorpromazine
Chlorpromazine results in decreased activity of DRD2 protein
CTD PMID:15694263 PMID:23611293 NCBI chr 9:49,251,633...49,319,477
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression
affects expression
ISO
EXP
Chlorpromazine analog results in increased expression of DUSP1 mRNA
Chlorpromazine affects the expression of DUSP1 mRNA
CTD PMID:15924885 PMID:20843724 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
JBrowse link
G Dusp9 dual specificity phosphatase 9 decreases expression ISO Chlorpromazine analog results in decreased expression of DUSP9 mRNA CTD PMID:15924885 NCBI chr  X:72,682,995...72,687,120
Ensembl chr  X:72,683,025...72,687,120
JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO Chlorpromazine analog results in decreased expression of E2F1 mRNA CTD PMID:15924885 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812
JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions
ISO Chlorpromazine results in increased expression of EGR1
[EGR1 binds to CDKN1A promoter] promotes the reaction [Chlorpromazine results in increased expression of CDKN1A mRNA]; EGR1 promotes the reaction [Chlorpromazine results in increased expression of CDKN1A mRNA]; MAPK1 affects the reaction [Chlorpromazine results in increased expression of EGR1]; MAPK3 affects the reaction [Chlorpromazine results in increased expression of EGR1]
CTD PMID:20368687 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Eif1 eukaryotic translation initiation factor 1 increases expression ISO Chlorpromazine results in increased expression of EIF1 mRNA CTD PMID:25596134 NCBI chr11:100,210,775...100,212,925
Ensembl chr11:100,210,711...100,212,922
JBrowse link
G Eno2 enolase 2, gamma neuronal increases expression ISO Chlorpromazine results in increased expression of ENO2 mRNA CTD PMID:25596134 NCBI chr 6:124,737,016...124,746,636
Ensembl chr 6:124,737,016...124,746,636
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO Chlorpromazine results in increased expression of ERO1A mRNA CTD PMID:25596134 NCBI chr14:45,520,544...45,556,029
Ensembl chr14:45,520,544...45,556,228
JBrowse link
G F2 coagulation factor II decreases expression ISO Chlorpromazine analog results in decreased expression of F2 mRNA CTD PMID:15924885 NCBI chr 2:91,442,742...91,466,802
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G Fabp1 fatty acid binding protein 1, liver increases expression ISO Chlorpromazine results in increased expression of FABP1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 6:71,176,863...71,182,018
Ensembl chr 6:71,176,811...71,182,007
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) increases expression ISO Chlorpromazine analog results in increased expression of FAS mRNA CTD PMID:15924885 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fbp1 fructose bisphosphatase 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of FBP1 mRNA CTD PMID:27344345 NCBI chr13:63,012,567...63,036,112
Ensembl chr13:63,012,567...63,036,096
JBrowse link
G Fbxo22 F-box protein 22 decreases expression ISO Chlorpromazine results in decreased expression of FBXO22 mRNA CTD PMID:25596134 NCBI chr 9:55,116,219...55,131,717
Ensembl chr 9:55,116,209...55,131,717
JBrowse link
G Fech ferrochelatase decreases expression ISO Chlorpromazine results in decreased expression of FECH mRNA CTD PMID:25596134 NCBI chr18:64,589,613...64,622,169
Ensembl chr18:64,585,985...64,623,322
JBrowse link
G Fetub fetuin beta multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of FETUB mRNA CTD PMID:27344345 NCBI chr16:22,737,132...22,758,518
Ensembl chr16:22,737,084...22,758,528
JBrowse link
G Fga fibrinogen alpha chain multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of FGA mRNA CTD PMID:27344345 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of FGF2 mRNA CTD PMID:27344345 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257
JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 decreases expression ISO Chlorpromazine analog results in decreased expression of FGFR1 mRNA CTD PMID:15924885 NCBI chr 8:26,008,775...26,065,734
Ensembl chr 8:26,003,670...26,065,734
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase decreases expression ISO Chlorpromazine results in decreased expression of FGR mRNA CTD PMID:25596134 NCBI chr 4:132,701,406...132,729,204
Ensembl chr 4:132,701,406...132,729,221
JBrowse link
G Fkbp5 FK506 binding protein 5 multiple interactions ISO Chlorpromazine inhibits the reaction [Lipopolysaccharides results in decreased expression of FKBP5 protein] CTD PMID:21034739 NCBI chr17:28,617,727...28,705,123
Ensembl chr17:28,618,068...28,736,501
JBrowse link
G Fndc4 fibronectin type III domain containing 4 increases expression ISO Chlorpromazine results in increased expression of FNDC4 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 5:31,449,586...31,453,279
Ensembl chr 5:31,449,586...31,453,424
JBrowse link
G Fos FBJ osteosarcoma oncogene affects expression EXP Chlorpromazine affects the expression of FOS mRNA CTD PMID:20843724 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Fosb FBJ osteosarcoma oncogene B affects expression EXP Chlorpromazine affects the expression of FOSB mRNA CTD PMID:20843724 NCBI chr 7:19,036,621...19,043,970
Ensembl chr 7:19,036,621...19,043,976
JBrowse link
G Fosl1 fos-like antigen 1 increases expression
affects expression
ISO
EXP
Chlorpromazine analog results in increased expression of FOSL1 mRNA
Chlorpromazine affects the expression of FOSL1 mRNA
CTD PMID:15924885 PMID:20843724 NCBI chr19:5,497,726...5,505,966
Ensembl chr19:5,497,575...5,505,974
JBrowse link
G Fosl2 fos-like antigen 2 affects expression EXP Chlorpromazine affects the expression of FOSL2 mRNA CTD PMID:20843724 NCBI chr 5:32,292,599...32,315,184
Ensembl chr 5:32,293,145...32,315,186
JBrowse link
G Fth1 ferritin heavy polypeptide 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of FTH1 mRNA CTD PMID:27344345 NCBI chr19:9,957,964...9,962,475
Ensembl chr19:9,957,962...9,962,462
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked decreases expression
multiple interactions
decreases activity
ISO Chlorpromazine analog results in decreased expression of G6PD mRNA
[Taurine co-treated with coenzyme Q10] inhibits the reaction [Chlorpromazine results in decreased activity of G6PD protein]; coenzyme Q10 inhibits the reaction [Chlorpromazine results in decreased activity of G6PD protein]; Taurine inhibits the reaction [Chlorpromazine results in decreased activity of G6PD protein]
CTD PMID:15924885 PMID:33548410 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800
JBrowse link
G Gad1 glutamate decarboxylase 1 decreases methylation
multiple interactions
EXP Chlorpromazine results in decreased methylation of GAD1 promoter
Valproic Acid promotes the reaction [Chlorpromazine results in decreased methylation of GAD1 promoter]
CTD PMID:19110320 NCBI chr 2:70,391,644...70,432,358
Ensembl chr 2:70,383,416...70,432,358
JBrowse link
G Gcgr glucagon receptor multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of GCGR mRNA CTD PMID:27344345 NCBI chr11:120,420,011...120,429,815
Ensembl chr11:120,421,525...120,429,812
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO Chlorpromazine results in decreased expression of GCLC mRNA CTD PMID:25596134 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Chlorpromazine results in increased expression of GDF15 mRNA CTD PMID:25596134 NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106
JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO Chlorpromazine results in increased expression of GDPD3 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 7:126,365,586...126,374,817
Ensembl chr 7:126,365,506...126,374,821
JBrowse link
G Gfap glial fibrillary acidic protein affects expression ISO Chlorpromazine affects the expression of GFAP mRNA CTD PMID:31324950 NCBI chr11:102,778,162...102,791,368
Ensembl chr11:102,778,162...102,791,738
JBrowse link
G Gpnmb glycoprotein (transmembrane) nmb increases expression ISO Chlorpromazine results in increased expression of GPNMB mRNA CTD PMID:25596134 NCBI chr 6:49,013,449...49,044,413
Ensembl chr 6:49,013,480...49,047,863
JBrowse link
G Gsr glutathione reductase decreases activity ISO Chlorpromazine results in decreased activity of GSR protein CTD PMID:6693892 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit affects activity ISO Chlorpromazine affects the activity of HIF1A protein CTD PMID:25596134 NCBI chr12:73,948,098...73,994,328
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase increases expression ISO Chlorpromazine results in increased expression of HMGCR mRNA CTD PMID:17052361 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 increases expression ISO Chlorpromazine results in increased expression of HMGCS1 mRNA CTD PMID:17052361 NCBI chr13:120,151,887...120,169,796
Ensembl chr13:120,151,915...120,169,796
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
affects expression
ISO Chlorpromazine results in increased expression of HMOX1 mRNA
Chlorpromazine affects the expression of HMOX1 mRNA
CTD PMID:15924885 PMID:25596134 PMID:31324950 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hpn hepsin increases expression ISO Chlorpromazine results in increased expression of HPN mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 7:30,798,150...30,814,751
Ensembl chr 7:30,798,150...30,814,715
JBrowse link
G Ibsp integrin binding sialoprotein decreases expression
multiple interactions
ISO Chlorpromazine results in decreased expression of IBSP mRNA
herbimycin inhibits the reaction [Chlorpromazine results in decreased expression of IBSP mRNA]; U 0126 inhibits the reaction [Chlorpromazine results in decreased expression of IBSP mRNA]
CTD PMID:16294319 NCBI chr 5:104,447,153...104,459,338
Ensembl chr 5:104,447,037...104,459,335
JBrowse link
G Ifnb1 interferon beta 1, fibroblast multiple interactions ISO Chlorpromazine promotes the reaction [PAM2-CSK4 results in increased expression of IFNB1 mRNA] CTD PMID:32796029 NCBI chr 4:88,440,262...88,441,031
Ensembl chr 4:88,440,262...88,441,011
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Chlorpromazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA CTD PMID:29594315 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Ifnlr1 interferon lambda receptor 1 increases expression EXP Chlorpromazine results in increased expression of IFNLR1 mRNA CTD PMID:21683644 NCBI chr 4:135,413,768...135,435,492
Ensembl chr 4:135,413,598...135,435,492
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO Chlorpromazine results in increased expression of IGFBP1 mRNA CTD PMID:15924885 NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546
JBrowse link
G Ikbkg inhibitor of kappaB kinase gamma increases expression ISO Chlorpromazine analog results in increased expression of IKBKG mRNA CTD PMID:15924885 NCBI chr  X:73,436,883...73,498,013
Ensembl chr  X:73,436,896...73,497,460
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Chlorpromazine CTD PMID:19362101 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Chlorpromazine results in decreased expression of IL1B mRNA CTD PMID:29594315 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Chlorpromazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; Chlorpromazine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]; Chlorpromazine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein] CTD PMID:11014349 PMID:29594315 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Chlorpromazine CTD PMID:19362101 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Inhbe inhibin beta-E increases expression ISO Chlorpromazine results in increased expression of INHBE mRNA CTD PMID:15342952 PMID:17175557 NCBI chr10:127,185,271...127,187,717
Ensembl chr10:127,184,726...127,190,280
JBrowse link
G Insig2 insulin induced gene 2 decreases expression ISO Chlorpromazine results in decreased expression of INSIG2 mRNA CTD PMID:25596134 NCBI chr 1:121,232,082...121,260,391
Ensembl chr 1:121,232,082...121,260,318
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions ISO Chlorpromazine results in decreased expression of and results in decreased phosphorylation of IRS2 protein; Chlorpromazine results in decreased expression of and results in increased degradation of IRS2 protein CTD PMID:17512020 PMID:18308779 NCBI chr 8:11,034,681...11,058,929
Ensembl chr 8:11,034,681...11,058,458
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 multiple interactions
decreases activity
ISO Chlorpromazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Chlorpromazine results in decreased activity of KCNH2 protein
CTD PMID:15071359 PMID:21158687 PMID:24052561 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
G Kcnn2 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 decreases activity ISO Chlorpromazine results in decreased activity of KCNN2 protein CTD PMID:10915830 NCBI chr18:45,401,754...45,818,954
Ensembl chr18:45,401,927...45,819,091
JBrowse link
G Klf4 Kruppel-like factor 4 (gut) multiple interactions
decreases expression
ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of KLF4 mRNA
Chlorpromazine results in decreased expression of KLF4 mRNA
CTD PMID:27344345 PMID:30703373 NCBI chr 4:55,527,137...55,536,984
Ensembl chr 4:55,527,143...55,532,466
JBrowse link
G Klkb1 kallikrein B, plasma 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of KLKB1 mRNA CTD PMID:27344345 NCBI chr 8:45,719,725...45,747,872
Ensembl chr 8:45,719,726...45,747,896
JBrowse link
G Kng2 kininogen 2 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of KNG1 mRNA CTD PMID:27344345 NCBI chr16:22,804,602...22,847,851
Ensembl chr16:22,804,604...22,848,232
JBrowse link
G Lats1 large tumor suppressor increases phosphorylation ISO Chlorpromazine results in increased phosphorylation of LATS1 protein CTD PMID:30703373 NCBI chr10:7,556,964...7,592,225
Ensembl chr10:7,556,978...7,592,224
JBrowse link
G Ldhc lactate dehydrogenase C multiple interactions
decreases activity
ISO [Taurine co-treated with coenzyme Q10] inhibits the reaction [Chlorpromazine results in decreased activity of LDHC protein]; coenzyme Q10 inhibits the reaction [Chlorpromazine results in decreased activity of LDHC protein]; Taurine inhibits the reaction [Chlorpromazine results in decreased activity of LDHC protein] CTD PMID:33548410 NCBI chr 7:46,510,687...46,527,571
Ensembl chr 7:46,510,627...46,527,566
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Chlorpromazine results in increased expression of LDLR mRNA CTD PMID:17052361 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
G Lep leptin increases expression ISO Chlorpromazine results in increased expression of LEP protein CTD PMID:17512020 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Lss lanosterol synthase increases expression ISO Chlorpromazine results in increased expression of LSS mRNA CTD PMID:15342952 PMID:17175557 NCBI chr10:76,367,303...76,392,973
Ensembl chr10:76,367,422...76,392,972
JBrowse link
G Map2 microtubule-associated protein 2 increases expression ISO Chlorpromazine results in increased expression of MAP2 mRNA CTD PMID:15079866 NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO Chlorpromazine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]
MAPK1 affects the reaction [Chlorpromazine results in increased expression of EGR1]
CTD PMID:11014349 PMID:20368687 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 decreases expression ISO Chlorpromazine analog results in decreased expression of MAPK14 mRNA CTD PMID:15924885 NCBI chr17:28,910,243...28,967,379
Ensembl chr17:28,910,303...28,967,380
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 decreases expression
multiple interactions
ISO Chlorpromazine analog results in decreased expression of MAPK3 mRNA
MAPK3 affects the reaction [Chlorpromazine results in increased expression of EGR1]
Chlorpromazine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein]
CTD PMID:11014349 PMID:15924885 PMID:20368687 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP [Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein; Chlorpromazine promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]; TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein]; TIRAP gene mutant form inhibits the reaction [Chlorpromazine promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]] CTD PMID:23238562 NCBI chr14:33,099,855...33,169,215
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mapkapk2 MAP kinase-activated protein kinase 2 increases expression ISO Chlorpromazine results in increased expression of MAPKAPK2 mRNA CTD PMID:19441803 NCBI chr 1:130,981,437...131,025,580
Ensembl chr 1:130,981,437...131,025,563
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 decreases expression ISO Chlorpromazine analog results in decreased expression of MCM3 mRNA CTD PMID:15924885 NCBI chr 1:20,873,188...20,890,536
Ensembl chr 1:20,873,192...20,890,536
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO Chlorpromazine analog results in decreased expression of MCM5 mRNA CTD PMID:15924885 NCBI chr 8:75,836,096...75,855,067
Ensembl chr 8:75,836,197...75,855,067
JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 increases expression ISO Chlorpromazine results in increased expression of MDM2 mRNA CTD PMID:25596134 NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663
JBrowse link
G Mitf melanogenesis associated transcription factor increases expression ISO Chlorpromazine results in increased expression of MITF protein CTD PMID:25449126 NCBI chr 6:97,783,966...97,998,321
Ensembl chr 6:97,784,013...97,998,310
JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 decreases expression ISO Chlorpromazine analog results in decreased expression of MKI67 mRNA CTD PMID:15924885 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO Chlorpromazine inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased expression of MMP9 mRNA]; Chlorpromazine inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased secretion of MMP9 protein] CTD PMID:25200491 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Msc musculin decreases expression ISO Chlorpromazine results in decreased expression of MSC mRNA CTD PMID:25596134 NCBI chr 1:14,823,570...14,826,190
Ensembl chr 1:14,823,570...14,826,216
JBrowse link
G Msh2 mutS homolog 2 decreases expression ISO Chlorpromazine results in decreased expression of MSH2 mRNA CTD PMID:15924885 NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141
JBrowse link
G Mst1 macrophage stimulating 1 (hepatocyte growth factor-like) increases phosphorylation ISO Chlorpromazine results in increased phosphorylation of MST1 protein CTD PMID:30703373 NCBI chr 9:107,957,607...107,962,226
Ensembl chr 9:107,957,635...107,962,202
JBrowse link
G Mt1 metallothionein 1 increases expression ISO Chlorpromazine results in increased expression of MT1A mRNA CTD PMID:8128501 NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955
JBrowse link
G Mybl2 myeloblastosis oncogene-like 2 decreases expression ISO Chlorpromazine analog results in decreased expression of MYBL2 mRNA CTD PMID:15924885 NCBI chr 2:162,896,246...162,926,608
Ensembl chr 2:162,896,607...162,926,608
JBrowse link
G Myc myelocytomatosis oncogene decreases expression ISO Chlorpromazine results in decreased expression of MYC mRNA CTD PMID:30703373 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression ISO Chlorpromazine results in increased expression of NAMPT mRNA CTD PMID:25596134 NCBI chr12:32,870,334...32,903,368
Ensembl chr12:32,869,544...32,903,348
JBrowse link
G Nanog Nanog homeobox decreases expression ISO Chlorpromazine results in decreased expression of NANOG mRNA CTD PMID:30703373 NCBI chr 6:122,684,448...122,691,592
Ensembl chr 6:122,684,448...122,691,592
JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 decreases expression ISO Chlorpromazine results in decreased expression of NDUFS3 protein CTD PMID:19441803 NCBI chr 2:90,724,971...90,735,065
Ensembl chr 2:90,724,978...90,735,171
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 multiple interactions EXP Chlorpromazine inhibits the reaction [Cadmium Chloride results in decreased expression of and affects the localization of NECTIN2 protein] CTD PMID:25046863 NCBI chr 7:19,450,569...19,483,498
Ensembl chr 7:19,450,569...19,484,408
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated gene 9 decreases expression ISO Chlorpromazine results in decreased expression of NEDD9 mRNA CTD PMID:25596134 NCBI chr13:41,463,392...41,640,836
Ensembl chr13:41,463,057...41,640,838
JBrowse link
G Nefh neurofilament, heavy polypeptide affects expression ISO Chlorpromazine affects the expression of NEFH mRNA CTD PMID:31324950 NCBI chr11:4,888,754...4,898,064
Ensembl chr11:4,888,754...4,898,064
JBrowse link
G Nfatc1 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 multiple interactions EXP Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA] CTD PMID:21869564 NCBI chr18:80,649,418...80,756,286
Ensembl chr18:80,649,420...80,756,286
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 decreases expression
affects activity
ISO Chlorpromazine results in decreased expression of NFE2L2 mRNA
Chlorpromazine affects the activity of NFE2L2 protein
CTD PMID:25596134 NCBI chr 2:75,505,857...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Ninj1 ninjurin 1 increases expression ISO Chlorpromazine results in increased expression of NINJ1 mRNA CTD PMID:25596134 NCBI chr13:49,341,005...49,349,727
Ensembl chr13:49,340,961...49,349,720
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO Chlorpromazine results in increased expression of NR0B2 mRNA CTD PMID:17175557 NCBI chr 4:133,280,687...133,283,997
Ensembl chr 4:133,280,687...133,283,847
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression ISO Chlorpromazine results in decreased expression of NR1H4 mRNA CTD PMID:27765674 PMID:28391356 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression
multiple interactions
ISO Chlorpromazine analog results in increased expression of NR1I2 mRNA
[Chlorpromazine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA
CTD PMID:15924885 PMID:17041008 NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity
increases expression
multiple interactions
EXP
ISO
Chlorpromazine results in increased activity of NR1I3 protein
Chlorpromazine results in increased expression of NR1I3 mRNA
[Chlorpromazine co-treated with Cholic Acids] affects the expression of NR1I3 mRNA; [Chlorpromazine results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; Chlorpromazine inhibits the reaction [Androstenols inhibits the reaction [NR1I3 protein results in increased expression of CYP2B6 mRNA]]
NR1I3 protein affects the reaction [Chlorpromazine results in increased expression of CYP2B10 mRNA]; NR1I3 protein affects the reaction [Chlorpromazine results in increased expression of CYP3A11 mRNA]
CTD PMID:10037683 PMID:12049174 PMID:12948398 PMID:17041008 PMID:22310298 More... NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions EXP Chlorpromazine inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein] CTD PMID:16581232 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474
JBrowse link
G Nupr1 nuclear protein transcription regulator 1 increases expression ISO Chlorpromazine results in increased expression of NUPR1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 7:126,222,418...126,224,642
Ensembl chr 7:126,222,421...126,230,033
JBrowse link
G Orc1 origin recognition complex, subunit 1 decreases expression ISO Chlorpromazine analog results in decreased expression of ORC1 mRNA CTD PMID:15924885 NCBI chr 4:108,436,651...108,472,030
Ensembl chr 4:108,436,620...108,472,030
JBrowse link
G Orm1 orosomucoid 1 affects binding
multiple interactions
ISO Chlorpromazine binds to ORM1 protein alternative form
Chlorpromazine inhibits the reaction [Warfarin binds to ORM1 protein alternative form]
CTD PMID:8946472 NCBI chr 4:63,262,793...63,266,400
Ensembl chr 4:63,262,797...63,266,400
JBrowse link
G Orm2 orosomucoid 2 affects binding
multiple interactions
ISO Chlorpromazine binds to ORM2 protein alternative form
Chlorpromazine inhibits the reaction [Imipramine binds to ORM2 protein alternative form]
CTD PMID:8946472 NCBI chr 4:63,280,543...63,284,114
Ensembl chr 4:63,280,686...63,284,115
JBrowse link
G Pdia2 protein disulfide isomerase associated 2 increases expression ISO Chlorpromazine analog results in increased expression of PDIA2 mRNA CTD PMID:15924885 NCBI chr17:26,414,973...26,418,108
Ensembl chr17:26,414,973...26,418,061
JBrowse link
G Pdia5 protein disulfide isomerase associated 5 decreases expression ISO Chlorpromazine results in decreased expression of PDIA5 mRNA CTD PMID:25596134 NCBI chr16:35,217,678...35,311,289
Ensembl chr16:35,217,682...35,311,243
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1 increases expression ISO Chlorpromazine results in increased expression of PDK1 mRNA CTD PMID:25596134 NCBI chr 2:71,703,398...71,734,202
Ensembl chr 2:71,703,568...71,734,202
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase, isoenzyme 4 increases expression ISO Chlorpromazine results in increased expression of PDK4 mRNA CTD PMID:25596134 NCBI chr 6:5,483,351...5,496,278
Ensembl chr 6:5,483,351...5,496,309
JBrowse link
G Phyh phytanoyl-CoA hydroxylase increases expression ISO Chlorpromazine results in increased expression of PHYH mRNA CTD PMID:15342952 NCBI chr 2:4,923,807...4,943,554
Ensembl chr 2:4,923,830...4,943,541
JBrowse link
G Pias1 protein inhibitor of activated STAT 1 increases expression EXP Chlorpromazine results in increased expression of PIAS1 mRNA CTD PMID:21683644 NCBI chr 9:62,785,648...62,888,161
Ensembl chr 9:62,785,650...62,895,206
JBrowse link
G Pim1 proviral integration site 1 increases expression ISO Chlorpromazine analog results in increased expression of PIM1 mRNA CTD PMID:15924885 NCBI chr17:29,709,759...29,715,085
Ensembl chr17:29,709,727...29,715,086
JBrowse link
G Pir pirin decreases expression ISO Chlorpromazine results in decreased expression of PIR mRNA CTD PMID:25596134 NCBI chr  X:163,052,427...163,156,009
Ensembl chr  X:163,052,367...163,156,007
JBrowse link
G Plin2 perilipin 2 increases expression ISO Chlorpromazine results in increased expression of PLIN2 mRNA CTD PMID:25596134 NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 decreases expression ISO Chlorpromazine results in decreased expression of PMEPA1 mRNA CTD PMID:25596134 NCBI chr 2:173,066,251...173,118,524
Ensembl chr 2:173,066,251...173,118,326
JBrowse link
G Pola1 polymerase (DNA directed), alpha 1 decreases expression ISO Chlorpromazine analog results in decreased expression of POLA1 mRNA CTD PMID:15924885 NCBI chr  X:92,348,372...92,675,993
Ensembl chr  X:92,348,373...92,675,761
JBrowse link
G Pold4 polymerase (DNA-directed), delta 4 increases expression ISO Chlorpromazine analog results in increased expression of POLD4 mRNA CTD PMID:15924885 NCBI chr19:4,281,947...4,283,688
Ensembl chr19:4,281,953...4,283,688
JBrowse link
G Pou5f1 POU domain, class 5, transcription factor 1 decreases expression ISO Chlorpromazine results in decreased expression of POU5F1 mRNA CTD PMID:30703373 NCBI chr17:35,816,929...35,821,674
Ensembl chr17:35,816,915...35,821,669
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma affects activity ISO Chlorpromazine affects the activity of PPARG protein CTD PMID:25596134 NCBI chr 6:115,337,840...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO Chlorpromazine results in increased expression of PPP1R15A mRNA CTD PMID:25596134 NCBI chr 7:45,172,341...45,175,692
Ensembl chr 7:45,172,340...45,175,692
JBrowse link
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit decreases phosphorylation ISO Chlorpromazine results in decreased phosphorylation of PRKAA1 protein CTD PMID:17512020 NCBI chr15:5,172,641...5,211,380
Ensembl chr15:5,173,343...5,211,380
JBrowse link
G Prl prolactin increases expression ISO Chlorpromazine results in increased expression of PRL protein CTD PMID:718334 PMID:996201 NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188
JBrowse link
G Rara retinoic acid receptor, alpha decreases expression ISO Chlorpromazine results in decreased expression of RARA mRNA CTD PMID:18246545 NCBI chr11:98,818,626...98,865,768
Ensembl chr11:98,818,644...98,865,768
JBrowse link
G Rnd1 Rho family GTPase 1 decreases expression ISO Chlorpromazine results in decreased expression of RND1 mRNA CTD PMID:25596134 NCBI chr15:98,567,086...98,575,342
Ensembl chr15:98,561,302...98,575,342
JBrowse link
G Rnd3 Rho family GTPase 3 decreases expression ISO Chlorpromazine results in decreased expression of RND3 mRNA CTD PMID:25596134 NCBI chr 2:51,020,451...51,039,123
Ensembl chr 2:51,020,450...51,039,123
JBrowse link
G Rnf121 ring finger protein 121 decreases expression ISO Chlorpromazine results in decreased expression of RNF121 mRNA CTD PMID:25596134 NCBI chr 7:101,668,344...101,721,712
Ensembl chr 7:101,668,344...101,714,676
JBrowse link
G Runx1 runt related transcription factor 1 increases expression ISO Chlorpromazine results in increased expression of RUNX1 mRNA CTD PMID:25596134 NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037
JBrowse link
G Rxrg retinoid X receptor gamma affects response to substance EXP RXRG protein affects the susceptibility to Chlorpromazine CTD PMID:10336693 NCBI chr 1:167,425,931...167,467,192
Ensembl chr 1:167,425,953...167,467,192
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression ISO Chlorpromazine results in increased expression of SAT1 mRNA CTD PMID:25596134 NCBI chr  X:153,996,122...153,999,445
Ensembl chr  X:153,996,128...153,999,445
JBrowse link
G Sc5d sterol-C5-desaturase increases expression ISO Chlorpromazine results in increased expression of SC5D mRNA CTD PMID:17052361 NCBI chr 9:42,162,888...42,175,607
Ensembl chr 9:42,162,891...42,175,552
JBrowse link
G Serpina3b serine (or cysteine) peptidase inhibitor, clade A, member 3B increases expression ISO Chlorpromazine results in increased expression of SERPINA3 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr12:104,094,245...104,105,805
Ensembl chr12:104,094,255...104,105,804
JBrowse link
G Sesn1 sestrin 1 decreases expression ISO Chlorpromazine results in decreased expression of SESN1 mRNA CTD PMID:25596134 NCBI chr10:41,686,570...41,784,432
Ensembl chr10:41,685,931...41,784,420
JBrowse link
G Sik1 salt inducible kinase 1 decreases expression ISO Chlorpromazine results in decreased expression of SIK1 mRNA CTD PMID:25596134 NCBI chr17:32,063,222...32,074,808
Ensembl chr17:32,063,224...32,074,778
JBrowse link
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 decreases expression ISO Chlorpromazine results in decreased expression of SLC10A1 mRNA CTD PMID:27765674 PMID:28391356 NCBI chr12:80,999,959...81,015,479
Ensembl chr12:80,999,957...81,015,479
JBrowse link
G Slc12a8 solute carrier family 12 (potassium/chloride transporters), member 8 increases expression ISO Chlorpromazine results in increased expression of SLC12A8 mRNA CTD PMID:25596134 NCBI chr16:33,337,440...33,484,508
Ensembl chr16:33,337,698...33,484,505
JBrowse link
G Slc19a1 solute carrier family 19 (folate transporter), member 1 multiple interactions
decreases activity
ISO Chlorpromazine inhibits the reaction [SLC19A1 protein results in increased uptake of Methotrexate]
Chlorpromazine results in decreased activity of SLC19A1 protein
CTD PMID:17482559 NCBI chr10:76,868,103...76,886,266
Ensembl chr10:76,868,075...76,896,836
JBrowse link
G Slc1a5 solute carrier family 1 (neutral amino acid transporter), member 5 increases expression ISO Chlorpromazine results in increased expression of SLC1A5 mRNA CTD PMID:25596134 NCBI chr 7:16,515,259...16,532,199
Ensembl chr 7:16,515,265...16,532,199
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Chlorpromazine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
G Slc22a7 solute carrier family 22 (organic anion transporter), member 7 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of SLC22A7 mRNA CTD PMID:27344345 NCBI chr17:46,743,111...46,749,403
Ensembl chr17:46,743,109...46,749,383
JBrowse link
G Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 decreases expression ISO Chlorpromazine results in decreased expression of SLC2A3 mRNA CTD PMID:15342952 NCBI chr 6:122,704,768...122,779,322
Ensembl chr 6:122,704,768...122,778,599
JBrowse link
G Slc31a1 solute carrier family 31, member 1 multiple interactions ISO Chlorpromazine inhibits the reaction [Copper affects the localization of SLC31A1 protein] CTD PMID:12501239 NCBI chr 4:62,278,821...62,310,006
Ensembl chr 4:62,278,964...62,310,006
JBrowse link
G Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 increases expression ISO Chlorpromazine results in increased expression of SLC3A2 mRNA CTD PMID:25596134 NCBI chr19:8,684,246...8,700,733
Ensembl chr19:8,684,246...8,700,733
JBrowse link
G Slc51b solute carrier family 51, beta subunit multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of SLC51B mRNA CTD PMID:27344345 NCBI chr 9:65,320,035...65,330,055
Ensembl chr 9:65,319,996...65,330,237
JBrowse link
G Slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 increases expression ISO Chlorpromazine results in increased expression of SLC6A6 mRNA CTD PMID:25596134 NCBI chr 6:91,661,031...91,736,044
Ensembl chr 6:91,661,034...91,736,047
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 decreases expression ISO Chlorpromazine results in decreased expression of SLCO2B1 mRNA CTD PMID:25596134 NCBI chr 7:99,307,011...99,360,547
Ensembl chr 7:99,307,011...99,360,547
JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions ISO Chlorpromazine inhibits the reaction [Copper inhibits the reaction [Trientine results in decreased activity of SOD1 protein]] CTD PMID:22362149 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Sox2 SRY (sex determining region Y)-box 2 decreases expression ISO Chlorpromazine results in decreased expression of SOX2 mRNA CTD PMID:30703373 NCBI chr 3:34,704,144...34,706,610
Ensembl chr 3:34,704,554...34,706,610
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of SPP1 mRNA CTD PMID:27344345 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
JBrowse link
G Spsb1 splA/ryanodine receptor domain and SOCS box containing 1 increases expression ISO Chlorpromazine results in increased expression of SPSB1 mRNA CTD PMID:25596134 NCBI chr 4:149,980,740...150,039,463
Ensembl chr 4:149,980,740...150,039,500
JBrowse link
G Src Rous sarcoma oncogene multiple interactions ISO Chlorpromazine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased phosphorylation of SRC protein] CTD PMID:29702141 NCBI chr 2:157,265,790...157,313,758
Ensembl chr 2:157,260,364...157,313,782
JBrowse link
G Srebf2 sterol regulatory element binding factor 2 multiple interactions ISO Chlorpromazine results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:17052361 NCBI chr15:82,031,470...82,089,580
Ensembl chr15:82,031,382...82,089,580
JBrowse link
G Strbp spermatid perinuclear RNA binding protein increases expression ISO Chlorpromazine results in increased expression of STRBP mRNA CTD PMID:25596134 NCBI chr 2:37,459,880...37,593,890
Ensembl chr 2:37,373,240...37,593,871
JBrowse link
G Sts steroid sulfatase multiple interactions ISO Chlorpromazine inhibits the reaction [Tretinoin results in increased activity of STS protein] CTD PMID:16178010 NCBI chr  X:168,856,332...169,015,037 JBrowse link
G Tagln transgelin decreases expression ISO Chlorpromazine results in decreased expression of TAGLN mRNA CTD PMID:17175557 NCBI chr 9:45,840,926...45,847,356
Ensembl chr 9:45,840,917...45,847,356
JBrowse link
G Tfdp1 transcription factor Dp 1 decreases expression ISO Chlorpromazine analog results in decreased expression of TFDP1 mRNA CTD PMID:15924885 NCBI chr 8:13,388,273...13,428,448
Ensembl chr 8:13,388,751...13,428,448
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase increases expression ISO Chlorpromazine results in increased expression of TIPARP mRNA CTD PMID:25596134 NCBI chr 3:65,435,868...65,462,939
Ensembl chr 3:65,435,831...65,462,939
JBrowse link
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein multiple interactions EXP TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TNF protein]; TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipoteichoic acid] results in increased expression of TNF protein]; TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein]; TIRAP gene mutant form inhibits the reaction [Chlorpromazine promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]]; TIRAP protein results in increased susceptibility to [Chlorpromazine co-treated with lipopolysaccharide, Escherichia coli O111 B4]; TIRAP protein results in increased susceptibility to [Chlorpromazine co-treated with lipoteichoic acid] CTD PMID:23238562 NCBI chr 9:35,095,687...35,111,587
Ensembl chr 9:35,095,847...35,111,587
JBrowse link
G Tnf tumor necrosis factor decreases expression
increases response to substance
multiple interactions
ISO
EXP
Chlorpromazine analog results in decreased expression of TNF protein; Chlorpromazine results in decreased expression of TNF mRNA
TNF protein results in increased susceptibility to Chlorpromazine
[Chlorpromazine co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TNF protein; [Chlorpromazine co-treated with lipoteichoic acid] results in increased expression of TNF protein; Chlorpromazine inhibits the reaction [[hydroquinone results in increased expression of TNF protein] which results in increased susceptibility to Methacholine Chloride]; Chlorpromazine inhibits the reaction [hydroquinone results in increased expression of TNF protein]; pyrazolanthrone inhibits the reaction [TNF protein results in increased susceptibility to Chlorpromazine]; TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TNF protein]; TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipoteichoic acid] results in increased expression of TNF protein]
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Chlorpromazine; Chlorpromazine results in decreased expression of and results in decreased activity of TNF protein
CTD PMID:8550079 PMID:15052360 PMID:19362101 PMID:20371967 PMID:22414385 More... NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfaip8 tumor necrosis factor, alpha-induced protein 8 increases expression ISO Chlorpromazine results in increased expression of TNFAIP8 mRNA CTD PMID:25596134 NCBI chr18:50,112,494...50,226,296
Ensembl chr18:50,112,494...50,240,240
JBrowse link
G Tnfrsf14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) increases expression ISO Chlorpromazine analog results in increased expression of TNFRSF14 mRNA CTD PMID:15924885 NCBI chr 4:155,002,944...155,013,077
Ensembl chr 4:155,006,390...155,013,020
JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 decreases activity
multiple interactions
EXP Chlorpromazine results in decreased activity of TNFSF11; Chlorpromazine results in decreased activity of TNFSF11 protein
Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]; Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of CALCR mRNA]; Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of CAR2 mRNA]; Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of DCSTAMP mRNA]; Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]
CTD PMID:21869564 NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483
JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 decreases expression ISO Chlorpromazine results in decreased expression of TRAFD1 mRNA CTD PMID:25596134 NCBI chr 5:121,509,788...121,524,543
Ensembl chr 5:121,509,788...121,523,695
JBrowse link
G Trf transferrin affects localization ISO Chlorpromazine affects the localization of TF protein CTD PMID:12501239 NCBI chr 9:103,086,075...103,107,485
Ensembl chr 9:103,081,200...103,107,643
JBrowse link
G Trp53 transformation related protein 53 affects activity ISO Chlorpromazine affects the activity of TP53 protein CTD PMID:25596134 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Tuba1a tubulin, alpha 1A decreases expression EXP Chlorpromazine results in decreased expression of TUBA1A mRNA CTD PMID:27015953 NCBI chr15:98,847,728...98,851,382
Ensembl chr15:98,847,718...98,851,584
JBrowse link
G Txn1 thioredoxin 1 decreases expression ISO Chlorpromazine results in decreased expression of TXN1 mRNA CTD PMID:25596134 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of TXNRD1 mRNA CTD PMID:27344345 NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546
JBrowse link
G Tyr tyrosinase increases expression ISO Chlorpromazine results in increased expression of TYR protein CTD PMID:25449126 NCBI chr 7:87,073,979...87,142,720
Ensembl chr 7:87,073,979...87,142,720
JBrowse link
G Ung uracil DNA glycosylase decreases expression ISO Chlorpromazine analog results in decreased expression of UNG mRNA CTD PMID:15924885 NCBI chr 5:114,268,427...114,277,382
Ensembl chr 5:114,268,447...114,277,384
JBrowse link
G Unkl unkempt family like zinc finger decreases expression ISO Chlorpromazine results in decreased expression of UNKL mRNA CTD PMID:25596134 NCBI chr17:25,407,336...25,453,417
Ensembl chr17:25,407,371...25,453,417
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Chlorpromazine analog results in increased expression of VEGFA mRNA CTD PMID:15924885 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Vegfb vascular endothelial growth factor B increases expression ISO Chlorpromazine results in increased expression of VEGFB mRNA CTD PMID:25596134 NCBI chr19:6,959,840...6,965,019
Ensembl chr19:6,959,841...6,965,019
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase1 increases expression ISO Chlorpromazine results in increased expression of WARS1 mRNA CTD PMID:25596134 NCBI chr12:108,825,956...108,860,100
Ensembl chr12:108,825,956...108,860,100
JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 increases expression ISO Chlorpromazine results in increased expression of WIPI1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr11:109,464,347...109,502,215
Ensembl chr11:109,464,157...109,502,793
JBrowse link
G Xbp1 X-box binding protein 1 affects activity
decreases expression
ISO Chlorpromazine affects the activity of XBP1 protein
Chlorpromazine results in decreased expression of XBP1 mRNA
CTD PMID:25596134 NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893
JBrowse link
G Xpc xeroderma pigmentosum, complementation group C decreases expression ISO Chlorpromazine results in decreased expression of XPC mRNA CTD PMID:25596134 NCBI chr 6:91,466,287...91,492,870
Ensembl chr 6:91,466,287...91,492,870
JBrowse link
G Xrcc4 X-ray repair complementing defective repair in Chinese hamster cells 4 decreases expression ISO Chlorpromazine results in decreased expression of XRCC4 mRNA CTD PMID:15924885 NCBI chr13:89,997,033...90,237,727
Ensembl chr13:89,922,146...90,237,727
JBrowse link
G Yap1 yes-associated protein 1 multiple interactions ISO Chlorpromazine results in decreased expression of and results in increased phosphorylation of and affects the localization of YAP1 protein CTD PMID:30703373 NCBI chr 9:7,932,000...8,004,890
Ensembl chr 9:7,932,000...8,004,597
JBrowse link
clopenthixol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO Clopenthixol results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
clozapine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A930009A15Rik RIKEN cDNA A930009A15 gene decreases expression ISO Clozapine results in decreased expression of DCD protein CTD PMID:34122009 NCBI chr10:115,399,555...115,418,359
Ensembl chr10:115,405,891...115,418,353
JBrowse link
G Aars alanyl-tRNA synthetase increases expression ISO Clozapine results in increased expression of AARS protein CTD PMID:34122009 NCBI chr 8:111,759,781...111,784,237
Ensembl chr 8:111,759,776...111,784,296
JBrowse link
G Abcb11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 decreases activity ISO Clozapine results in decreased activity of ABCB11 protein CTD PMID:22646477 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,960
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A decreases activity
multiple interactions
ISO Clozapine results in decreased activity of ABCB1 protein
Clozapine inhibits the reaction [Bromocriptine results in increased expression of ABCB1 protein]; Clozapine inhibits the reaction [N-n-propylnorapomorphine results in increased expression of ABCB1 protein]; Clozapine inhibits the reaction [Quinpirole results in increased expression of ABCB1 protein]
CTD PMID:9111066 PMID:16810505 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcb1b ATP-binding cassette, sub-family B (MDR/TAP), member 1B multiple interactions ISO Clozapine inhibits the reaction [Bromocriptine results in increased activity of ABCB1B promoter]; Clozapine inhibits the reaction [N-n-propylnorapomorphine results in increased activity of ABCB1B promoter]; Clozapine inhibits the reaction [Quinpirole results in increased activity of ABCB1B promoter] CTD PMID:9111066 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315
JBrowse link
G Abce1 ATP-binding cassette, sub-family E (OABP), member 1 increases expression ISO Clozapine results in increased expression of ABCE1 protein CTD PMID:34122009 NCBI chr 8:80,410,071...80,438,369
Ensembl chr 8:80,410,091...80,438,369
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 increases expression ISO Clozapine results in increased expression of ABCG1 mRNA CTD PMID:17346280 NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) multiple interactions ISO Clozapine inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone] CTD PMID:18834354 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661
JBrowse link
G Ablim2 actin-binding LIM protein 2 increases expression ISO Clozapine results in increased expression of ABLIM2 mRNA CTD PMID:17346280 NCBI chr 5:35,915,200...36,042,323
Ensembl chr 5:35,915,224...36,042,317
JBrowse link
G Acat2 acetyl-Coenzyme A acetyltransferase 2 increases expression ISO Clozapine results in increased expression of ACAT2 mRNA CTD PMID:17052361 NCBI chr17:13,161,929...13,179,612
Ensembl chr17:13,161,777...13,179,634
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO Clozapine results in increased expression of ACOT2 protein CTD PMID:34122009 NCBI chr12:84,034,635...84,040,651
Ensembl chr12:84,034,635...84,040,647
JBrowse link
G Acot7 acyl-CoA thioesterase 7 decreases expression ISO Clozapine results in decreased expression of ACOT7 protein CTD PMID:34122009 NCBI chr 4:152,258,872...152,356,312
Ensembl chr 4:152,262,591...152,356,312
JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl multiple interactions ISO [Clozapine co-treated with 1-(carboxymethylthio)tetradecane] results in increased activity of ACOX1 protein; [Clozapine co-treated with 1-(carboxymethylthio)tetradecane] results in increased expression of ACOX1 mRNA CTD PMID:23226405 NCBI chr11:116,062,709...116,089,871
Ensembl chr11:116,062,714...116,089,871
JBrowse link
G Actb actin, beta decreases expression ISO Clozapine results in decreased expression of ACTB protein CTD PMID:34122009 NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509
JBrowse link
G Actbl2 actin, beta-like 2 increases expression ISO Clozapine results in increased expression of ACTBL2 protein CTD PMID:34122009 NCBI chr13:111,391,547...111,394,283
Ensembl chr13:111,391,547...111,394,283
JBrowse link
G Actr3 ARP3 actin-related protein 3 decreases expression ISO Clozapine results in decreased expression of ACTR3 protein CTD PMID:34122009 NCBI chr 1:125,320,642...125,363,464
Ensembl chr 1:125,320,642...125,363,464
JBrowse link
G Actr5 ARP5 actin-related protein 5 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of ACTR5 protein CTD PMID:34122009 NCBI chr 2:158,466,800...158,481,131
Ensembl chr 2:158,466,808...158,481,131
JBrowse link
G Adam1a a disintegrin and metallopeptidase domain 1a decreases expression ISO Clozapine results in decreased expression of ADAM1A mRNA CTD PMID:16715494 NCBI chr 5:121,656,667...121,659,758
Ensembl chr 5:121,656,639...121,660,134
JBrowse link
G Adamts12 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of ADAMTS12 protein CTD PMID:34122009 NCBI chr15:11,064,781...11,349,321
Ensembl chr15:11,064,876...11,349,317
JBrowse link
G Adcy5 adenylate cyclase 5 affects response to substance
multiple interactions
EXP ADCY5 protein affects the susceptibility to Clozapine
SCH 23390 inhibits the reaction [ADCY5 protein affects the susceptibility to Clozapine]
CTD PMID:12223546 NCBI chr16:34,974,863...35,126,113
Ensembl chr16:34,975,247...35,126,108
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of ADH5 protein CTD PMID:34122009 NCBI chr 3:138,142,961...138,161,260
Ensembl chr 3:138,148,854...138,161,260
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression
increases expression
multiple interactions
ISO
EXP
Clozapine results in decreased expression of ADIPOQ protein
Clozapine results in increased expression of ADIPOQ protein
Clozapine results in increased expression of ADIPOQ mRNA
Berberine inhibits the reaction [Clozapine results in increased expression of ADIPOQ mRNA]
CTD PMID:17933447 PMID:18162013 PMID:20564506 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Adora2a adenosine A2a receptor decreases expression EXP Clozapine results in decreased expression of ADORA2A mRNA CTD PMID:17266109 NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618
JBrowse link
G Adra1a adrenergic receptor, alpha 1a multiple interactions ISO Clozapine binds to and results in decreased activity of ADRA1A protein CTD PMID:16545797 NCBI chr14:66,872,700...67,008,689
Ensembl chr14:66,872,700...67,008,617
JBrowse link
G Agpat1 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) decreases expression EXP Clozapine results in decreased expression of AGPAT1 mRNA CTD PMID:14647396 NCBI chr17:34,823,169...34,832,423
Ensembl chr17:34,823,236...34,832,423
JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) multiple interactions ISO Clozapine inhibits the reaction [Dopamine promotes the reaction [AGT protein results in increased secretion of Aldosterone]]; Clozapine promotes the reaction [Raclopride promotes the reaction [Dopamine promotes the reaction [AGT protein results in increased secretion of Aldosterone]]] CTD PMID:11549694 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 increases expression ISO Clozapine results in increased expression of AIMP1 protein CTD PMID:34122009 NCBI chr 3:132,366,259...132,390,151
Ensembl chr 3:132,366,242...132,390,131
JBrowse link
G Ak1 adenylate kinase 1 decreases expression ISO Clozapine results in decreased expression of AK1 protein CTD PMID:34122009 NCBI chr 2:32,511,770...32,525,070
Ensembl chr 2:32,511,770...32,525,070
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 increases expression
decreases expression
increases phosphorylation
ISO Clozapine results in increased expression of AKT1 mRNA; Clozapine results in increased expression of AKT1 protein
Clozapine results in decreased expression of AKT1 mRNA
Clozapine results in increased phosphorylation of AKT1 protein
CTD PMID:15860345 PMID:19440698 NCBI chr12:112,620,255...112,641,318
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Akt2 thymoma viral proto-oncogene 2 increases expression ISO Clozapine results in increased expression of AKT2 mRNA CTD PMID:15860345 NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251
JBrowse link
G Alb albumin multiple interactions
affects binding
ISO Clozapine results in decreased expression of and results in decreased reduction of ALB protein
[[[stearic acid binds to ALB protein] which affects the susceptibility to Clozapine] which affects the reduction of Cysteine] which affects the activity of ALB protein; [[stearic acid binds to ALB protein] which affects the susceptibility to Clozapine] which affects the reduction of Cysteine; [stearic acid binds to ALB protein] which affects the susceptibility to Clozapine; stearic acid inhibits the reaction [Clozapine binds to ALB protein]
CTD PMID:31400341 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 increases expression EXP Clozapine results in increased expression of ALDH1A1 mRNA CTD PMID:17266109 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829
JBrowse link
G Aldoa aldolase A, fructose-bisphosphate increases expression ISO Clozapine results in increased expression of ALDOA mRNA CTD PMID:15860345 NCBI chr 7:126,394,406...126,400,166
Ensembl chr 7:126,394,406...126,399,923
Ensembl chr 7:126,394,406...126,399,923
JBrowse link
G Aldob aldolase B, fructose-bisphosphate increases expression ISO Clozapine results in increased expression of ALDOB protein CTD PMID:34122009 NCBI chr 4:49,535,993...49,549,546
Ensembl chr 4:49,535,995...49,549,546
JBrowse link
G Aldoc aldolase C, fructose-bisphosphate decreases expression
increases expression
EXP
ISO
Clozapine results in decreased expression of ALDOC mRNA
Clozapine results in increased expression of ALDOC mRNA
CTD PMID:15860345 PMID:16465460 NCBI chr11:78,213,899...78,218,607
Ensembl chr11:78,213,794...78,218,607
JBrowse link
G Alyref Aly/REF export factor decreases expression ISO Clozapine results in decreased expression of ALYREF protein CTD PMID:34122009 NCBI chr11:120,485,330...120,489,342
Ensembl chr11:120,482,947...120,489,191
JBrowse link
G Anxa1 annexin A1 decreases expression ISO Clozapine results in decreased expression of ANXA1 protein CTD PMID:34122009 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308
JBrowse link
G Anxa5 annexin A5 decreases expression ISO Clozapine results in decreased expression of ANXA5 protein CTD PMID:34122009 NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043
JBrowse link
G Anxa6 annexin A6 decreases expression ISO Clozapine results in decreased expression of ANXA6 protein CTD PMID:34122009 NCBI chr11:54,869,779...54,924,297
Ensembl chr11:54,869,934...54,924,271
JBrowse link
G Ap1s1 adaptor protein complex AP-1, sigma 1 decreases expression ISO Clozapine results in decreased expression of AP1S1 mRNA CTD PMID:17175557 NCBI chr 5:137,063,847...137,074,962
Ensembl chr 5:137,063,847...137,074,989
JBrowse link
G Ap2b1 adaptor-related protein complex 2, beta 1 subunit increases expression ISO Clozapine results in increased expression of AP2B1 mRNA CTD PMID:15860345 NCBI chr11:83,189,545...83,295,861
Ensembl chr11:83,189,850...83,295,861
JBrowse link
G Ap3b1 adaptor-related protein complex 3, beta 1 subunit increases expression ISO Clozapine results in increased expression of AP3B1 protein CTD PMID:34122009 NCBI chr13:94,492,332...94,702,838
Ensembl chr13:94,495,468...94,702,825
JBrowse link
G Apoa5 apolipoprotein A-V affects response to substance ISO APOA5 gene polymorphism affects the susceptibility to Clozapine CTD PMID:17726453 NCBI chr 9:46,179,906...46,183,219
Ensembl chr 9:46,179,931...46,183,217
JBrowse link
G Apod apolipoprotein D increases expression EXP Clozapine results in increased expression of APOD mRNA; Clozapine results in increased expression of APOD protein CTD PMID:11158250 PMID:14647396 PMID:17266109 NCBI chr16:31,115,010...31,133,626
Ensembl chr16:31,115,010...31,133,626
JBrowse link
G Arc activity regulated cytoskeletal-associated protein decreases expression ISO Clozapine results in decreased expression of ARC mRNA CTD PMID:18208916 NCBI chr15:74,540,930...74,544,419
Ensembl chr15:74,540,932...74,544,419
JBrowse link
G Arhgef9 CDC42 guanine nucleotide exchange factor (GEF) 9 decreases expression EXP Clozapine results in decreased expression of ARHGEF9 mRNA CTD PMID:17266109 NCBI chr  X:94,092,536...94,240,801
Ensembl chr  X:94,092,541...94,240,462
JBrowse link
G Arl8a ADP-ribosylation factor-like 8A decreases expression ISO Clozapine results in decreased expression of ARL8A protein CTD PMID:34122009 NCBI chr 1:135,074,572...135,084,007
Ensembl chr 1:135,074,562...135,084,007
JBrowse link
G Armt1 acidic residue methyltransferase 1 increases expression ISO Clozapine results in increased expression of ARMT1 protein CTD PMID:34122009 NCBI chr10:4,382,572...4,405,140
Ensembl chr10:4,382,467...4,405,141
JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 affects expression EXP Clozapine affects the expression of ARPC4 mRNA CTD PMID:14647396 NCBI chr 6:113,355,074...113,367,408
Ensembl chr 6:113,355,076...113,367,409
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 increases expression ISO Clozapine results in increased expression of ASAH1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 8:41,793,683...41,850,681
Ensembl chr 8:41,793,234...41,827,810
JBrowse link
G Asns asparagine synthetase increases expression ISO Clozapine results in increased expression of ASNS mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 6:7,675,165...7,693,209
Ensembl chr 6:7,675,169...7,693,254
JBrowse link
G Asph aspartate-beta-hydroxylase increases expression ISO Clozapine results in increased expression of ASPH protein CTD PMID:34122009 NCBI chr 4:9,449,085...9,669,344
Ensembl chr 4:9,448,069...9,669,344
JBrowse link
G Ass1 argininosuccinate synthetase 1 increases expression ISO Clozapine results in increased expression of ASS1 protein CTD PMID:34122009 NCBI chr 2:31,360,282...31,410,682
Ensembl chr 2:31,360,219...31,410,684
JBrowse link
G Atad3a ATPase family, AAA domain containing 3A decreases expression ISO Clozapine results in decreased expression of ATAD3A protein CTD PMID:34122009 NCBI chr 4:155,825,097...155,845,579
Ensembl chr 4:155,825,098...155,845,550
JBrowse link
G Atp2a3 ATPase, Ca++ transporting, ubiquitous increases expression ISO Clozapine results in increased expression of ATP2A3 protein CTD PMID:34122009 NCBI chr11:72,851,995...72,883,869
Ensembl chr11:72,851,995...72,883,870
JBrowse link
G Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit decreases expression ISO Clozapine results in decreased expression of ATP5F1B protein CTD PMID:19441803 NCBI chr10:127,919,176...127,926,257
Ensembl chr10:127,919,142...127,926,260
JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b increases expression ISO Clozapine results in increased expression of ATP5F1 protein CTD PMID:34122009 NCBI chr 3:105,850,014...105,866,579
Ensembl chr 3:105,850,014...105,867,415
JBrowse link
G Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A decreases expression ISO Clozapine results in decreased expression of ATP6V1A protein CTD PMID:34122009 NCBI chr16:43,905,765...43,960,064
Ensembl chr16:43,905,765...43,960,068
JBrowse link
G Atp6v1b1 ATPase, H+ transporting, lysosomal V1 subunit B1 decreases expression ISO Clozapine results in decreased expression of ATP6V1B1 protein CTD PMID:34122009 NCBI chr 6:83,719,999...83,735,837
Ensembl chr 6:83,719,972...83,735,837
JBrowse link
G Atp6v1b2 ATPase, H+ transporting, lysosomal V1 subunit B2 decreases expression ISO Clozapine results in decreased expression of ATP6V1B2 protein CTD PMID:19441803 PMID:34122009 NCBI chr 8:69,541,388...69,566,370
Ensembl chr 8:69,541,298...69,566,363
JBrowse link
G Atxn10 ataxin 10 increases expression ISO Clozapine results in increased expression of ATXN10 protein CTD PMID:34122009 NCBI chr15:85,220,456...85,348,038
Ensembl chr15:85,220,446...85,347,413
JBrowse link
G Axin2 axin 2 decreases expression ISO Clozapine results in decreased expression of AXIN2 mRNA CTD PMID:16715494 NCBI chr11:108,808,654...108,841,609
Ensembl chr11:108,811,175...108,841,609
JBrowse link
G Bax BCL2-associated X protein increases expression
multiple interactions
decreases expression
ISO Clozapine results in increased expression of BAX mRNA; Clozapine results in increased expression of BAX protein
CSF3 protein inhibits the reaction [Clozapine results in increased expression of BAX mRNA]
Clozapine results in decreased expression of BAX protein
CTD PMID:16160616 PMID:17069804 NCBI chr 7:45,111,119...45,116,344
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of BAZ1B protein CTD PMID:34122009 NCBI chr 5:135,214,094...135,274,985
Ensembl chr 5:135,216,118...135,274,983
JBrowse link
G Bcar1 breast cancer anti-estrogen resistance 1 decreases expression ISO Clozapine results in decreased expression of BCAR1 protein CTD PMID:34122009 NCBI chr 8:112,437,106...112,470,481
Ensembl chr 8:112,437,106...112,470,441
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 increases expression ISO Clozapine results in increased expression of BCL2 mRNA; Clozapine results in increased expression of BCL2 protein CTD PMID:15126120 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l14 BCL2-like 14 (apoptosis facilitator) decreases expression ISO Clozapine results in decreased expression of BCL2L14 protein CTD PMID:34122009 NCBI chr 6:134,373,292...134,415,687
Ensembl chr 6:134,373,281...134,415,699
JBrowse link
G Bdnf brain derived neurotrophic factor decreases expression
increases expression
ISO Clozapine results in decreased expression of BDNF mRNA
Clozapine results in increased expression of BDNF mRNA; Clozapine results in increased expression of BDNF protein
CTD PMID:11488957 PMID:12478621 PMID:17442489 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Bet1l Bet1 golgi vesicular membrane trafficking protein like decreases expression ISO Clozapine results in decreased expression of BET1L mRNA CTD PMID:15860345 NCBI chr 7:140,433,297...140,437,306
Ensembl chr 7:140,433,307...140,437,490
JBrowse link
G Bik BCL2-interacting killer multiple interactions
increases expression
ISO CSF3 protein inhibits the reaction [Clozapine results in increased expression of BIK mRNA] CTD PMID:16160616 NCBI chr15:83,410,992...83,428,836
Ensembl chr15:83,411,063...83,428,835
JBrowse link
G Bptf bromodomain PHD finger transcription factor decreases expression EXP Clozapine results in decreased expression of BPTF mRNA CTD PMID:14647396 NCBI chr11:106,923,907...107,022,982
Ensembl chr11:106,923,907...107,022,953
JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 increases expression ISO Clozapine results in increased expression of BZW1 protein CTD PMID:34122009 NCBI chr 1:58,432,057...58,446,513
Ensembl chr 1:58,432,057...58,446,512
JBrowse link
G Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit decreases expression EXP
ISO
Clozapine results in decreased expression of CACNA1A mRNA CTD PMID:14647396 PMID:16715494 NCBI chr 8:85,065,257...85,366,880
Ensembl chr 8:85,065,268...85,366,875
JBrowse link
G Calm2 calmodulin 2 increases expression ISO Clozapine results in increased expression of CALM2 mRNA CTD PMID:19289156 NCBI chr17:87,740,829...87,754,363
Ensembl chr17:87,740,840...87,754,363
JBrowse link
G Calr calreticulin decreases expression ISO Clozapine results in decreased expression of CALR protein CTD PMID:34122009 NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563
JBrowse link
G Calu calumenin decreases expression ISO Clozapine results in decreased expression of CALU protein CTD PMID:34122009 NCBI chr 6:29,348,105...29,376,674
Ensembl chr 6:29,348,068...29,377,109
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha decreases expression
increases expression
EXP
ISO
Clozapine results in decreased expression of CAMK2A mRNA
Clozapine results in increased expression of CAMK2A mRNA
Clozapine results in decreased expression of CAMK2A protein
CTD PMID:15860345 PMID:17266109 PMID:19289156 NCBI chr18:61,058,379...61,121,224
Ensembl chr18:61,058,690...61,121,224
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II, beta decreases expression ISO Clozapine results in decreased expression of CAMK2B mRNA CTD PMID:15860345 NCBI chr11:5,919,642...6,016,401
Ensembl chr11:5,919,644...6,016,362
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II, delta decreases expression ISO Clozapine results in decreased expression of CAMK2D mRNA CTD PMID:15860345 NCBI chr 3:126,389,136...126,639,975
Ensembl chr 3:126,389,951...126,639,975
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV increases expression
decreases expression
ISO Clozapine results in increased expression of CAMK4 mRNA
Clozapine results in decreased expression of CAMK4 protein
CTD PMID:15860345 PMID:19289156 NCBI chr18:33,067,995...33,328,820
Ensembl chr18:33,067,984...33,324,281
JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1, alpha decreases expression ISO Clozapine results in decreased expression of CAMKK1 protein CTD PMID:19289156 NCBI chr11:72,906,869...72,932,899
Ensembl chr11:72,909,834...72,932,899
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2, beta decreases expression ISO Clozapine results in decreased expression of CAMKK2 protein CTD PMID:19289156 NCBI chr 5:122,856,064...122,918,295
Ensembl chr 5:122,869,233...122,917,472
JBrowse link
G Canx calnexin decreases expression ISO Clozapine results in decreased expression of CANX protein CTD PMID:34122009 NCBI chr11:50,184,784...50,216,500
Ensembl chr11:50,184,788...50,216,500
JBrowse link
G Cars cysteinyl-tRNA synthetase increases expression ISO Clozapine results in increased expression of CARS protein CTD PMID:34122009 NCBI chr 7:143,110,967...143,153,827
Ensembl chr 7:143,110,967...143,153,827
JBrowse link
G Cartpt CART prepropeptide decreases expression ISO Clozapine results in decreased expression of CARTPT mRNA CTD PMID:14696011 NCBI chr13:100,034,991...100,037,191
Ensembl chr13:100,034,997...100,037,599
JBrowse link
G Casp1 caspase 1 increases activity ISO Clozapine results in increased activity of CASP1 protein CTD PMID:34935985 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO Clozapine results in increased activity of CASP3 protein
Palmitic Acid promotes the reaction [Clozapine results in increased activity of CASP3 protein]
CTD PMID:22700542 PMID:24709159 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp7 caspase 7 increases activity
multiple interactions
ISO Clozapine results in increased activity of CASP7 protein
Palmitic Acid promotes the reaction [Clozapine results in increased activity of CASP7 protein]
CTD PMID:22700542 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776
JBrowse link
G Cat catalase multiple interactions EXP Clozapine inhibits the reaction [Corticosterone results in increased activity of CAT protein]; Clozapine inhibits the reaction [Lipopolysaccharides inhibits the reaction [Corticosterone results in increased activity of CAT protein]] CTD PMID:14730115 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 increases expression ISO Clozapine results in increased expression of CCAR1 protein CTD PMID:34122009 NCBI chr10:62,579,707...62,628,147
Ensembl chr10:62,579,707...62,628,065
JBrowse link
G Ccdc173 coiled-coil domain containing 173 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of CCDC173 protein CTD PMID:34122009 NCBI chr 2:69,587,736...69,619,971
Ensembl chr 2:69,588,377...69,619,919
JBrowse link
G Ccdc47 coiled-coil domain containing 47 multiple interactions
increases expression
ISO [Cuprizone co-treated with Clozapine] results in increased expression of CCDC47 protein
Clozapine results in increased expression of CCDC47 protein
CTD PMID:34122009 NCBI chr11:106,090,086...106,107,349
Ensembl chr11:106,088,234...106,107,170
JBrowse link
G Cck cholecystokinin multiple interactions
increases expression
ISO Clozapine inhibits the reaction [Dizocilpine Maleate results in decreased expression of CCK mRNA]; Clozapine inhibits the reaction [Dizocilpine Maleate results in decreased expression of CCK protein]
Clozapine results in increased expression of CCK mRNA
CTD PMID:10974607 PMID:16567023 NCBI chr 9:121,318,890...121,324,760
Ensembl chr 9:121,318,890...121,324,760
JBrowse link
G Cckbr cholecystokinin B receptor increases expression EXP Clozapine results in increased expression of CCKBR mRNA CTD PMID:17266109 NCBI chr 7:105,074,882...105,085,546
Ensembl chr 7:105,074,938...105,120,105
JBrowse link
G Ccl1 chemokine (C-C motif) ligand 1 decreases expression ISO Clozapine results in decreased expression of CCL1 mRNA CTD PMID:17346280 NCBI chr11:82,067,492...82,070,638
Ensembl chr11:82,067,483...82,196,516
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Clozapine results in decreased expression of CCND1 mRNA CTD PMID:15860345 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ccnd3 cyclin D3 increases expression ISO Clozapine results in increased expression of CCND3 mRNA CTD PMID:15860345 NCBI chr17:47,815,976...47,910,614
Ensembl chr17:47,815,976...47,910,616
JBrowse link
G Ccnl1 cyclin L1 increases expression ISO Clozapine results in increased expression of CCNL1 mRNA CTD PMID:15860345 NCBI chr 3:65,853,333...65,869,451
Ensembl chr 3:65,853,572...65,865,670
JBrowse link
G Cct7 chaperonin containing Tcp1, subunit 7 (eta) decreases expression ISO Clozapine results in decreased expression of CCT7 protein CTD PMID:34122009 NCBI chr 6:85,428,487...85,445,459
Ensembl chr 6:85,428,496...85,445,457
JBrowse link
G Cd276 CD276 antigen decreases expression ISO Clozapine results in decreased expression of CD276 protein CTD PMID:34122009 NCBI chr 9:58,431,583...58,462,316
Ensembl chr 9:58,431,581...58,462,720
JBrowse link
G Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) increases expression ISO Clozapine results in increased expression of CDIPT protein CTD PMID:34122009 NCBI chr 7:126,575,630...126,579,671
Ensembl chr 7:126,575,086...126,579,673
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression ISO Clozapine results in increased expression of CDK4 mRNA CTD PMID:15860345 NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789
JBrowse link
G Cdk5 cyclin-dependent kinase 5 increases expression ISO Clozapine results in increased expression of CDK5 mRNA CTD PMID:15860345 NCBI chr 5:24,612,595...24,628,737
Ensembl chr 5:24,623,239...24,628,528
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) increases expression EXP Clozapine results in increased expression of CDK5R1 mRNA CTD PMID:17266109 NCBI chr11:80,367,849...80,372,010
Ensembl chr11:80,367,849...80,372,010
JBrowse link
G Cebpa CCAAT/enhancer binding protein (C/EBP), alpha multiple interactions
increases expression
EXP Berberine inhibits the reaction [Clozapine results in increased expression of CEBPA mRNA]; Berberine inhibits the reaction [Clozapine results in increased expression of CEBPA protein]
Clozapine results in increased expression of CEBPA mRNA; Clozapine results in increased expression of CEBPA protein
CTD PMID:20564506 NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353
JBrowse link
G Cenpv centromere protein V increases expression ISO Clozapine results in increased expression of CENPV protein CTD PMID:34122009 NCBI chr11:62,415,770...62,430,695
Ensembl chr11:62,415,772...62,430,087
JBrowse link
G Chchd2 coiled-coil-helix-coiled-coil-helix domain containing 2 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of CHCHD2 protein CTD PMID:34122009 NCBI chr 5:129,910,002...129,916,311
Ensembl chr 5:129,909,997...129,916,311
JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 decreases expression ISO Clozapine results in decreased expression of CHD4 protein CTD PMID:34122009 NCBI chr 6:125,072,943...125,107,554
Ensembl chr 6:125,072,944...125,107,554
JBrowse link
G Chga chromogranin A decreases expression
increases expression
ISO Clozapine results in decreased expression of CHGA mRNA
Clozapine results in increased expression of CHGA mRNA
CTD PMID:12437575 NCBI chr12:102,521,200...102,531,286
Ensembl chr12:102,521,228...102,531,287
JBrowse link
G Chl1 cell adhesion molecule L1-like decreases expression EXP Clozapine results in decreased expression of CHL1 mRNA CTD PMID:14647396 NCBI chr 6:103,487,372...103,709,999
Ensembl chr 6:103,487,547...103,727,172
JBrowse link
G Chn1 chimerin 1 decreases expression EXP Clozapine results in decreased expression of CHN1 mRNA CTD PMID:14647396 NCBI chr 2:73,441,004...73,605,723
Ensembl chr 2:73,441,004...73,605,690
JBrowse link
G Chordc1 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 increases expression ISO Clozapine results in increased expression of CHORDC1 protein CTD PMID:34122009 NCBI chr 9:18,203,563...18,225,296
Ensembl chr 9:18,203,421...18,228,738
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1, CNS affects binding
increases expression
multiple interactions
ISO Clozapine analog binds to CHRM1 protein; Clozapine binds to CHRM1 protein
Clozapine results in increased expression of CHRM1 protein
Clozapine inhibits the reaction [Dextroamphetamine results in decreased expression of CHRM1 protein]
CTD PMID:11997696 PMID:16983399 PMID:18806925 NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951
JBrowse link
G Ckap4 cytoskeleton-associated protein 4 increases expression ISO Clozapine results in increased expression of CKAP4 protein CTD PMID:34122009 NCBI chr10:84,362,169...84,369,752
Ensembl chr10:84,362,169...84,369,926
JBrowse link
G Clic1 chloride intracellular channel 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of CLIC1 protein CTD PMID:34122009 NCBI chr17:35,269,219...35,277,695
Ensembl chr17:35,268,942...35,277,725
JBrowse link
G Clic4 chloride intracellular channel 4 (mitochondrial) increases expression ISO Clozapine results in increased expression of CLIC4 protein CTD PMID:34122009 NCBI chr 4:134,941,280...135,000,071
Ensembl chr 4:134,941,280...135,000,125
JBrowse link
G Clock circadian locomotor output cycles kaput affects response to substance ISO CLOCK gene SNP affects the susceptibility to Clozapine CTD PMID:15331141 NCBI chr 5:76,357,715...76,452,675
Ensembl chr 5:76,357,715...76,452,639
JBrowse link
G Clta clathrin, light polypeptide (Lca) decreases expression ISO Clozapine results in decreased expression of CLTA mRNA CTD PMID:15860345 NCBI chr 4:44,003,816...44,032,846
Ensembl chr 4:44,004,452...44,032,846
JBrowse link
G Cltb clathrin, light polypeptide (Lcb) decreases expression ISO Clozapine results in decreased expression of CLTB mRNA CTD PMID:15860345 NCBI chr13:54,740,199...54,759,186
Ensembl chr13:54,740,214...54,759,157
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases expression
increases expression
EXP
ISO
Clozapine results in decreased expression of CNP mRNA
Clozapine results in decreased expression of CNP protein
Clozapine results in increased expression of CNP mRNA
CTD PMID:17266109 PMID:34122009 NCBI chr11:100,465,765...100,472,565
Ensembl chr11:100,465,730...100,482,555
JBrowse link
G Coil coilin increases expression ISO Clozapine results in increased expression of COIL mRNA CTD PMID:16715494 NCBI chr11:88,864,761...88,882,439
Ensembl chr11:88,861,078...88,882,439
JBrowse link
G Col5a2 collagen, type V, alpha 2 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of COL5A2 protein CTD PMID:34122009 NCBI chr 1:45,413,491...45,542,442
Ensembl chr 1:45,413,481...45,542,442
JBrowse link
G Comt catechol-O-methyltransferase multiple interactions
affects response to substance
increases response to substance
ISO [tolcapone results in decreased activity of COMT protein] promotes the reaction [Clozapine results in increased abundance of Dopamine]
COMT protein affects the susceptibility to Clozapine
COMT gene polymorphism results in increased susceptibility to Clozapine
CTD PMID:15190105 PMID:17123785 NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602
JBrowse link
G Cops3 COP9 signalosome subunit 3 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of COPS3 protein CTD PMID:34122009 NCBI chr11:59,708,621...59,739,071
Ensembl chr11:59,708,621...59,730,664
JBrowse link
G Coro1b coronin, actin binding protein 1B decreases expression ISO Clozapine results in decreased expression of CORO1B protein CTD PMID:34122009 NCBI chr19:4,198,603...4,204,034
Ensembl chr19:4,198,618...4,204,034
JBrowse link
G Cplx2 complexin 2 decreases expression EXP Clozapine results in decreased expression of CPLX2 mRNA CTD PMID:17266109 NCBI chr13:54,455,447...54,531,736
Ensembl chr13:54,519,162...54,531,730
Ensembl chr13:54,519,162...54,531,730
JBrowse link
G Cpn1 carboxypeptidase N, polypeptide 1 increases expression ISO Clozapine results in increased expression of CPN1 mRNA CTD PMID:16715494 NCBI chr19:43,944,746...43,974,990
Ensembl chr19:43,944,746...43,974,995
JBrowse link
G Cpne1 copine I decreases expression ISO Clozapine results in decreased expression of CPNE1 protein CTD PMID:34122009 NCBI chr 2:155,913,761...155,953,885
Ensembl chr 2:155,913,762...155,953,885
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 multiple interactions ISO [Clozapine co-treated with 1-(carboxymethylthio)tetradecane] results in increased activity of CPT2 protein; [Clozapine co-treated with 1-(carboxymethylthio)tetradecane] results in increased expression of CPT2 mRNA CTD PMID:23226405 NCBI chr 4:107,761,179...107,780,786
Ensembl chr 4:107,761,178...107,780,807
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
decreases phosphorylation
EXP Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of CREB1 protein]
Clozapine results in decreased phosphorylation of CREB1 protein
CTD PMID:12871586 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Crh corticotropin releasing hormone decreases expression ISO Clozapine results in decreased expression of CRH mRNA CTD PMID:16205782 NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560
JBrowse link
G Crhbp corticotropin releasing hormone binding protein decreases expression ISO Clozapine results in decreased expression of CRHBP mRNA CTD PMID:16715494 NCBI chr13:95,567,884...95,581,339
Ensembl chr13:95,567,879...95,581,432
JBrowse link
G Crp C-reactive protein, pentraxin-related increases expression ISO Clozapine results in increased expression of CRP protein CTD PMID:17685758 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) multiple interactions ISO CSF3 protein inhibits the reaction [Clozapine results in increased expression of BAX mRNA]; CSF3 protein inhibits the reaction [Clozapine results in increased expression of BIK mRNA]; CSF3 protein inhibits the reaction [Clozapine results in increased expression of TP53 mRNA] CTD PMID:16160616 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455
JBrowse link
G Csnk2a1 casein kinase 2, alpha 1 polypeptide decreases expression ISO Clozapine results in decreased expression of CSNK2A1 mRNA CTD PMID:16715494 NCBI chr 2:152,067,851...152,123,772
Ensembl chr 2:152,068,759...152,123,772
JBrowse link
G Cst3 cystatin C increases expression EXP Clozapine results in increased expression of CST3 mRNA CTD PMID:14647396 NCBI chr 2:148,713,642...148,717,432
Ensembl chr 2:148,713,642...148,717,612
JBrowse link
G Cstf1 cleavage stimulation factor, 3' pre-RNA, subunit 1 decreases expression ISO Clozapine results in decreased expression of CSTF1 protein CTD PMID:34122009 NCBI chr 2:172,212,565...172,224,369
Ensembl chr 2:172,212,601...172,224,368
JBrowse link
G Cstf2 cleavage stimulation factor, 3' pre-RNA subunit 2 decreases expression ISO Clozapine results in decreased expression of CSTF2 protein CTD PMID:34122009 NCBI chr  X:132,959,925...132,987,571
Ensembl chr  X:132,959,936...132,987,568
JBrowse link
G Ctbp1 C-terminal binding protein 1 increases expression ISO Clozapine results in increased expression of CTBP1 protein CTD PMID:34122009 NCBI chr 5:33,405,067...33,432,467
Ensembl chr 5:33,405,067...33,432,338
JBrowse link
G Ctnnb1 catenin (cadherin associated protein), beta 1 increases expression
multiple interactions
ISO Clozapine results in increased expression of CTNNB1 protein
DRD2 protein affects the reaction [Clozapine results in increased expression of CTNNB1 protein]
CTD PMID:16144542 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Ctrl chymotrypsin-like increases expression ISO Clozapine results in increased expression of CTRL mRNA CTD PMID:16715494 NCBI chr 8:106,658,626...106,660,494
Ensembl chr 8:106,658,635...106,660,494
JBrowse link
G Ctsk cathepsin K increases expression ISO Clozapine results in increased expression of CTSK mRNA CTD PMID:16715494 NCBI chr 3:95,406,521...95,416,698
Ensembl chr 3:95,406,567...95,416,673
JBrowse link
G Cttn cortactin increases expression ISO Clozapine results in increased expression of CTTN protein CTD PMID:34122009 NCBI chr 7:143,989,461...144,024,743
Ensembl chr 7:143,989,470...144,024,746
JBrowse link
G Cul2 cullin 2 increases expression ISO Clozapine results in increased expression of CUL2 protein CTD PMID:34122009 NCBI chr18:3,382,970...3,436,700
Ensembl chr18:3,382,988...3,436,377
JBrowse link
G Cul3 cullin 3 increases expression ISO Clozapine results in increased expression of CUL3 protein CTD PMID:34122009 NCBI chr 1:80,242,640...80,318,407
Ensembl chr 1:80,242,640...80,318,197
JBrowse link
G Cxcl1 chemokine (C-X-C motif) ligand 1 decreases expression
increases secretion
multiple interactions
ISO Clozapine results in decreased expression of CXCL1 mRNA
Clozapine results in increased secretion of CXCL1 protein
belnacasan inhibits the reaction [Clozapine results in increased secretion of CXCL1 protein]
CTD PMID:17346280 PMID:34935985 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974
JBrowse link
G Cxcl3 chemokine (C-X-C motif) ligand 3 decreases expression ISO Clozapine results in decreased expression of CXCL1 mRNA CTD PMID:17346280 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459
JBrowse link
G Cyb5b cytochrome b5 type B increases expression ISO Clozapine results in increased expression of CYB5B mRNA CTD PMID:19441803 NCBI chr 8:107,877,293...107,914,102
Ensembl chr 8:107,877,272...107,914,103
JBrowse link
G Cyb5r1 cytochrome b5 reductase 1 increases expression ISO Clozapine results in increased expression of CYB5R1 protein CTD PMID:34122009 NCBI chr 1:134,333,519...134,339,476
Ensembl chr 1:134,333,297...134,339,478
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases activity
increases metabolic processing
ISO Clozapine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
Clozapine results in decreased activity of CYP1A1 protein
CYP1A1 protein results in increased metabolism of Clozapine
CTD PMID:18493746 PMID:18809730 PMID:33814510 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases response to substance
multiple interactions
increases metabolic processing
increases expression
affects metabolic processing
affects response to substance
decreases metabolic processing
ISO
EXP
CYP1A2 gene SNP results in decreased susceptibility to Clozapine
Clozapine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
CYP1A2 protein results in increased metabolism of Clozapine
Clozapine results in increased expression of CYP1A2 mRNA
CYP1A2 gene polymorphism affects the metabolism of Clozapine; CYP1A2 protein affects the metabolism of Clozapine; CYP1A2 protein polymorphism affects the metabolism of Clozapine
[Ciprofloxacin results in decreased activity of CYP1A2 protein] which results in increased abundance of Clozapine; [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Clozapine; Clozapine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Smoke affects the reaction [CYP1A2 gene polymorphism affects the metabolism of Clozapine]; Smoke promotes the reaction [CYP1A2 protein results in increased metabolism of Clozapine]
CYP1A2 gene SNP affects the susceptibility to Clozapine; CYP1A2 protein affects the susceptibility to Clozapine
CYP1A2 gene SNP results in increased metabolism of Clozapine; CYP1A2 protein results in increased metabolism of Clozapine
CYP1A2 gene SNP results in decreased metabolism of Clozapine
CTD PMID:11151749 PMID:11763009 PMID:12919186 PMID:12969762 PMID:15206669 More... NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases metabolic processing
decreases activity
ISO CYP1B1 protein results in increased metabolism of Clozapine
Clozapine results in decreased activity of CYP1B1 protein
CTD PMID:18809730 PMID:33814510 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 increases metabolic processing ISO CYP2C8 protein results in increased metabolism of Clozapine CTD PMID:18809730 PMID:27320963 NCBI chr19:39,275,488...39,319,157
Ensembl chr19:39,257,849...39,319,157
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 multiple interactions
increases metabolic processing
ISO [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Clozapine
CYP2C19 protein results in increased metabolism of Clozapine
CTD PMID:18809730 PMID:23397584 PMID:27320963 NCBI chr19:39,378,000...39,451,547
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 multiple interactions
increases metabolic processing
ISO [Clozapine results in decreased activity of CYP2C9 protein] which results in increased susceptibility to Phenytoin; [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Clozapine
CYP2C9 protein results in increased metabolism of Clozapine
CTD PMID:17961958 PMID:18809730 PMID:23397584 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 multiple interactions
increases metabolic processing
ISO [Clozapine results in decreased activity of CYP2C9 protein] which results in increased susceptibility to Phenytoin; [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Clozapine
CYP2C9 protein results in increased metabolism of Clozapine
CTD PMID:17961958 PMID:18809730 PMID:23397584 NCBI chr19:39,102,342...39,175,200
Ensembl chr19:39,102,342...39,175,516
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 affects metabolic processing
increases metabolic processing
multiple interactions
ISO CYP2D6 protein affects the metabolism of Clozapine
CYP2D6 protein results in increased metabolism of Clozapine
[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Clozapine
CTD PMID:15286053 PMID:18809730 PMID:23397584 PMID:27320963 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
G Cyp2j9 cytochrome P450, family 2, subfamily j, polypeptide 9 increases metabolic processing ISO CYP2J2 protein results in increased metabolism of Clozapine CTD PMID:18809730 NCBI chr 4:96,456,661...96,480,748
Ensembl chr 4:96,456,666...96,479,815
JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 increases metabolic processing ISO CYP3A5 protein results in increased metabolism of Clozapine CTD PMID:18809730 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774
JBrowse link
G Dab1 disabled 1 increases expression ISO Clozapine results in increased expression of DAB1 mRNA CTD PMID:19359144 NCBI chr 4:103,476,425...104,602,041
Ensembl chr 4:103,476,556...104,602,041
JBrowse link
G Dcaf6 DDB1 and CUL4 associated factor 6 decreases expression EXP Clozapine results in decreased expression of DCAF6 mRNA CTD PMID:14647396 NCBI chr 1:165,157,069...165,288,475
Ensembl chr 1:165,156,267...165,288,044
JBrowse link
G Dclk1 doublecortin-like kinase 1 increases expression EXP
ISO
Clozapine results in increased expression of DCLK1 mRNA CTD PMID:15860345 PMID:18797397 NCBI chr 3:55,149,724...55,446,489
Ensembl chr 3:55,149,785...55,446,489
JBrowse link
G Ddc dopa decarboxylase multiple interactions
increases expression
EXP Clozapine results in increased expression of and results in increased activity of DDC protein
Clozapine results in increased expression of DDC mRNA
CTD PMID:16415089 NCBI chr11:11,764,101...11,848,144
Ensembl chr11:11,764,101...11,848,144
JBrowse link
G Ddx46 DEAD box helicase 46 increases expression ISO Clozapine results in increased expression of DDX46 protein CTD PMID:34122009 NCBI chr13:55,782,790...55,829,080
Ensembl chr13:55,782,840...55,829,069
JBrowse link
G Dennd10 DENN domain containing 10 increases expression ISO Clozapine results in increased expression of DENND10 mRNA CTD PMID:16715494 NCBI chr19:60,799,993...60,824,673
Ensembl chr19:60,800,023...60,824,665
JBrowse link
G Depp1 DEPP1 autophagy regulator increases expression ISO Clozapine results in increased expression of DEPP1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 6:116,627,645...116,629,808
Ensembl chr 6:116,627,570...116,629,755
JBrowse link
G Dgcr6 DiGeorge syndrome critical region gene 6 decreases expression ISO Clozapine results in decreased expression of DGCR6 protein CTD PMID:34122009 NCBI chr16:17,870,724...17,889,497
Ensembl chr16:17,870,724...17,889,496
JBrowse link
G Dgka diacylglycerol kinase, alpha decreases expression ISO Clozapine results in decreased expression of DGKA mRNA CTD PMID:15860345 NCBI chr10:128,556,000...128,581,002
Ensembl chr10:128,556,003...128,580,724
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase increases expression ISO Clozapine results in increased expression of DHCR24 protein CTD PMID:34122009 NCBI chr 4:106,418,235...106,446,310
Ensembl chr 4:106,418,235...106,446,310
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase increases expression ISO Clozapine results in increased expression of DHCR7 mRNA CTD PMID:17052361 NCBI chr 7:143,376,825...143,402,147
Ensembl chr 7:143,376,882...143,402,147
JBrowse link
G Dhx30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 increases expression ISO Clozapine results in increased expression of DHX30 protein CTD PMID:34122009 NCBI chr 9:109,913,387...109,946,728
Ensembl chr 9:109,913,388...109,946,898
JBrowse link
G Dhx38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 decreases expression ISO Clozapine results in decreased expression of DHX38 protein CTD PMID:34122009 NCBI chr 8:110,274,631...110,292,493
Ensembl chr 8:110,274,643...110,292,493
JBrowse link
G Disc1 disrupted in schizophrenia 1 decreases response to substance
affects response to substance
ISO DISC1 gene mutant form results in decreased susceptibility to Clozapine
DISC1 protein affects the susceptibility to Clozapine
CTD PMID:20531374 NCBI chr 8:125,773,928...125,991,882
Ensembl chr 8:125,780,934...125,988,597
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) decreases expression
increases expression
ISO Clozapine results in decreased expression of DLAT mRNA
Clozapine results in increased expression of DLAT protein
CTD PMID:15860345 PMID:34122009 NCBI chr 9:50,545,933...50,571,080
Ensembl chr 9:50,545,933...50,571,080
JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 increases expression ISO Clozapine results in increased expression of DLG2 protein CTD PMID:34122009 NCBI chr 7:90,125,399...92,098,454
Ensembl chr 7:90,125,880...92,098,455
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) decreases expression ISO Clozapine results in decreased expression of DLST protein CTD PMID:34122009 NCBI chr12:85,157,597...85,180,865
Ensembl chr12:85,157,607...85,181,619
JBrowse link
G Dnah11 dynein, axonemal, heavy chain 11 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of DNAH11 protein CTD PMID:34122009 NCBI chr12:117,841,717...118,162,778
Ensembl chr12:117,841,717...118,162,778
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of DNAJA3 protein CTD PMID:34122009 NCBI chr16:4,501,934...4,525,559
Ensembl chr16:4,457,853...4,525,559
JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 increases expression ISO Clozapine results in increased expression of DNAJB11 protein CTD PMID:34122009 NCBI chr16:22,676,595...22,698,384
Ensembl chr16:22,676,595...22,698,384
JBrowse link
G Dpf1 double PHD fingers 1 affects expression EXP Clozapine affects the expression of DPF1 mRNA CTD PMID:14647396 NCBI chr 7:29,003,366...29,017,017
Ensembl chr 7:29,003,376...29,017,668
JBrowse link
G Dpp3 dipeptidylpeptidase 3 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of DPP3 protein CTD PMID:34122009 NCBI chr19:4,957,257...4,978,315
Ensembl chr19:4,957,257...4,978,315
JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 decreases expression ISO Clozapine results in decreased expression of DPYSL3 protein CTD PMID:34122009 NCBI chr18:43,454,044...43,571,351
Ensembl chr18:43,454,049...43,571,351
JBrowse link
G Dpysl4 dihydropyrimidinase-like 4 decreases expression ISO Clozapine results in decreased expression of DPYSL4 protein CTD PMID:34122009 NCBI chr 7:138,665,917...138,681,711
Ensembl chr 7:138,665,917...138,682,620
JBrowse link
G Dr1 down-regulator of transcription 1 decreases expression ISO Clozapine results in decreased expression of DR1 protein CTD PMID:34122009 NCBI chr 5:108,416,763...108,428,387
Ensembl chr 5:108,416,763...108,428,392
JBrowse link
G Drd1 dopamine receptor D1 affects binding
decreases expression
affects response to substance
ISO
EXP
Clozapine binds to DRD1 protein
Clozapine results in decreased expression of DRD1 mRNA
Clozapine analog binds to DRD1 protein
DRD1 gene polymorphism affects the susceptibility to Clozapine; DRD1 protein affects the susceptibility to Clozapine
CTD PMID:1352677 PMID:9723970 PMID:11997696 PMID:17092969 PMID:17266109 NCBI chr13:54,205,202...54,209,677
Ensembl chr13:54,205,202...54,209,724
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
affects binding
affects response to substance
decreases expression
increases response to substance
ISO
EXP
[Clozapine co-treated with DRD2 gene polymorphism] results in increased secretion of PRL protein
Clozapine binds to DRD2 protein
DRD2 protein affects the susceptibility to Clozapine
Clozapine results in decreased expression of DRD2 mRNA
Clozapine analog binds to DRD2 protein; Clozapine binds to DRD2 protein
[Clozapine binds to and results in decreased activity of DRD2 protein] which results in increased expression of PPP3CA protein; Bromocriptine promotes the reaction [Clozapine results in decreased expression of DRD2 mRNA]; Clozapine binds to and results in decreased activity of DRD2 protein; Clozapine promotes the reaction [Dopamine binds to DRD2 protein]; DRD2 protein affects the reaction [Clozapine results in increased expression of CTNNB1 protein]; DRD2 protein affects the reaction [Clozapine results in increased expression of DVL3 protein]; DRD2 protein affects the reaction [Clozapine results in increased expression of GSK3A protein]; DRD2 protein affects the reaction [Clozapine results in increased expression of GSK3B protein]
[Clozapine co-treated with Bromocriptine] results in decreased expression of DRD2 mRNA
Clozapine binds to DRD2 protein alternative form
DRD2 gene SNP results in increased susceptibility to Clozapine
DRD2 gene affects the susceptibility to Clozapine; DRD2 gene polymorphism affects the susceptibility to Clozapine
CTD PMID:1352677 PMID:9723970 PMID:11997696 PMID:12476322 PMID:15286066 More... NCBI chr 9:49,251,633...49,319,477
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
G Drd3 dopamine receptor D3 affects response to substance
multiple interactions
decreases response to substance
ISO
EXP
DRD3 protein affects the susceptibility to Clozapine
DRD3 protein affects the reaction [Clozapine results in increased expression of FOSB protein alternative form]
DRD3 gene polymorphism results in decreased susceptibility to Clozapine
CTD PMID:15579174 PMID:20029384 NCBI chr16:43,574,285...43,646,353
Ensembl chr16:43,574,389...43,643,295
JBrowse link
G Drd4 dopamine receptor D4 affects binding
multiple interactions
affects response to substance
ISO Clozapine binds to DRD4 protein
Clozapine binds to Drd4 protein
Clozapine inhibits the reaction [Dopamine results in increased activity of DRD4 protein]
Clozapine analog binds to DRD4 protein
DRD4 gene polymorphism affects the susceptibility to Clozapine
CTD
RGD
PMID:11997696 PMID:16223700 PMID:31323226 PMID:8078498 RGD:7248459 NCBI chr 7:140,871,887...140,876,377
Ensembl chr 7:140,871,919...140,876,377
JBrowse link
G Drp2 dystrophin related protein 2 increases expression ISO Clozapine results in increased expression of DRP2 mRNA alternative form CTD PMID:16715494 NCBI chr  X:133,304,873...133,357,323
Ensembl chr  X:133,305,300...133,357,322
JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 increases response to substance
affects response to substance
ISO DTNBP1 gene polymorphism results in increased susceptibility to Clozapine
DTNBP1 protein affects the susceptibility to Clozapine
CTD PMID:19369910 NCBI chr13:45,075,552...45,155,614
Ensembl chr13:45,075,551...45,155,623
JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression ISO Clozapine results in decreased expression of DUSP1 mRNA CTD PMID:15860345 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression ISO Clozapine results in decreased expression of DUSP6 mRNA CTD PMID:15860345 NCBI chr10:99,098,676...99,103,351
Ensembl chr10:99,099,093...99,103,351
JBrowse link
G Dvl3 dishevelled segment polarity protein 3 increases expression
multiple interactions
ISO Clozapine results in increased expression of DVL3 protein
DRD2 protein affects the reaction [Clozapine results in increased expression of DVL3 protein]
CTD PMID:16144542 NCBI chr16:20,335,694...20,352,763
Ensembl chr16:20,335,732...20,352,760
JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 decreases expression ISO Clozapine results in decreased expression of DYNC1LI1 protein CTD PMID:34122009 NCBI chr 9:114,517,899...114,552,856
Ensembl chr 9:114,517,858...114,553,370
JBrowse link
G Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 decreases expression ISO Clozapine results in decreased expression of DYNC1LI2 protein CTD PMID:34122009 NCBI chr 8:105,144,306...105,170,415
Ensembl chr 8:105,144,312...105,169,679
JBrowse link
G E130112N10Rik RIKEN cDNA E130112N10 gene increases expression ISO Clozapine results in increased expression of VAMP1 mRNA CTD PMID:15860345 NCBI chr 6:125,208,232...125,216,897
Ensembl chr 6:125,192,514...125,222,927
JBrowse link
G Edc4 enhancer of mRNA decapping 4 increases expression ISO Clozapine results in increased expression of EDC4 protein CTD PMID:34122009 NCBI chr 8:106,607,505...106,619,857
Ensembl chr 8:106,607,513...106,621,540
JBrowse link
G Eef1a2 eukaryotic translation elongation factor 1 alpha 2 increases expression ISO Clozapine results in increased expression of EEF1A2 protein CTD PMID:34122009 NCBI chr 2:180,783,551...180,798,808
Ensembl chr 2:180,789,446...180,798,807
JBrowse link
G Eef1d eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) decreases expression ISO Clozapine results in decreased expression of EEF1D protein CTD PMID:34122009 NCBI chr15:75,766,645...75,781,430
Ensembl chr15:75,766,054...75,781,405
JBrowse link
G Egr1 early growth response 1 decreases expression ISO Clozapine results in decreased expression of EGR1 mRNA; Clozapine results in decreased expression of EGR1 protein CTD PMID:17028028 PMID:18208916 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Egr2 early growth response 2 affects expression
decreases expression
EXP
ISO
Clozapine affects the expression of EGR2 mRNA
Clozapine results in decreased expression of EGR2 protein
CTD PMID:17028028 PMID:19401217 NCBI chr10:67,370,334...67,383,354
Ensembl chr10:67,371,305...67,378,018
JBrowse link
G Egr3 early growth response 3 affects response to substance EXP EGR3 protein affects the susceptibility to Clozapine CTD PMID:17637609 NCBI chr14:70,314,766...70,320,062
Ensembl chr14:70,314,652...70,320,063
JBrowse link
G Eif2s3x eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked increases expression ISO Clozapine results in increased expression of EIF2S3 protein CTD PMID:34122009 NCBI chr  X:93,232,315...93,256,257
Ensembl chr  X:93,232,313...93,256,468
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of EIF3C protein CTD PMID:34122009 NCBI chr 7:126,146,083...126,165,538
Ensembl chr 7:126,145,627...126,165,583
JBrowse link
G Eif3j1 eukaryotic translation initiation factor 3, subunit J1 increases expression ISO Clozapine results in increased expression of EIF3J protein CTD PMID:34122009 NCBI chr 2:121,859,061...121,884,113
Ensembl chr 2:121,859,027...121,887,079
JBrowse link
G Eif3m eukaryotic translation initiation factor 3, subunit M multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of EIF3M protein CTD PMID:34122009 NCBI chr 2:104,830,001...104,847,372
Ensembl chr 2:104,830,001...104,847,425
JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of EIF4A3 protein CTD PMID:34122009 NCBI chr11:119,179,189...119,190,869
Ensembl chr11:119,179,189...119,190,915
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of EIF4E protein CTD PMID:34122009 NCBI chr 3:138,231,952...138,265,457
Ensembl chr 3:138,231,940...138,265,457
JBrowse link
G Eif5b eukaryotic translation initiation factor 5B increases expression ISO Clozapine results in increased expression of EIF5B protein CTD PMID:34122009 NCBI chr 1:38,037,091...38,094,660
Ensembl chr 1:38,037,091...38,094,660
JBrowse link
G Eif6 eukaryotic translation initiation factor 6 decreases expression ISO Clozapine results in decreased expression of EIF6 protein CTD PMID:34122009 NCBI chr 2:155,661,757...155,668,845
Ensembl chr 2:155,661,752...155,668,845
JBrowse link
G Elk1 ELK1, member of ETS oncogene family decreases phosphorylation EXP Clozapine results in decreased phosphorylation of ELK1 protein CTD PMID:12871586 NCBI chr  X:20,799,634...20,816,847
Ensembl chr  X:20,799,634...20,816,847
JBrowse link
G Eno1 enolase 1, alpha non-neuron increases expression ISO Clozapine results in increased expression of ENO1 mRNA CTD PMID:15860345 NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336
JBrowse link
G Eno3 enolase 3, beta muscle increases expression ISO Clozapine results in increased expression of ENO3 protein CTD PMID:34122009 NCBI chr11:70,543,973...70,553,339
Ensembl chr11:70,548,028...70,553,339
JBrowse link
G Epha7 Eph receptor A7 increases expression EXP Clozapine results in increased expression of EPHA7 mRNA CTD PMID:17266109 NCBI chr 4:28,811,840...28,969,391
Ensembl chr 4:28,813,131...28,967,499
JBrowse link
G Ephb3 Eph receptor B3 increases expression ISO Clozapine results in increased expression of EPHB3 protein CTD PMID:34122009 NCBI chr16:21,023,370...21,042,059
Ensembl chr16:21,023,505...21,042,055
JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 decreases expression ISO Clozapine results in decreased expression of ERAP1 protein CTD PMID:34122009 NCBI chr13:74,787,692...74,841,324
Ensembl chr13:74,787,687...74,841,320
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 affects phosphorylation ISO Clozapine affects the phosphorylation of ERBB2 protein CTD PMID:26961615 NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 multiple interactions ISO Clozapine results in increased expression of and results in increased phosphorylation of ERBB4 protein CTD PMID:26961615 NCBI chr 1:68,071,063...69,147,756
Ensembl chr 1:68,071,345...69,147,218
JBrowse link
G Erh ERH mRNA splicing and mitosis factor increases expression ISO Clozapine results in increased expression of ERH protein CTD PMID:34122009 NCBI chr12:80,680,795...80,690,885
Ensembl chr12:80,680,796...80,691,115
JBrowse link
G Erp44 endoplasmic reticulum protein 44 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of ERP44 protein CTD PMID:34122009 NCBI chr 4:48,190,711...48,279,635
Ensembl chr 4:48,193,323...48,279,558
JBrowse link
G Ewsr1 Ewing sarcoma breakpoint region 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of EWSR1 protein CTD PMID:34122009 NCBI chr11:5,019,687...5,049,314
Ensembl chr11:5,019,689...5,049,266
JBrowse link
G Exosc4 exosome component 4 increases expression ISO Clozapine results in increased expression of EXOSC4 protein CTD PMID:34122009 NCBI chr15:76,211,597...76,214,870
Ensembl chr15:76,211,597...76,214,877
JBrowse link
G Ezr ezrin decreases expression ISO Clozapine results in decreased expression of EZR protein CTD PMID:34122009 NCBI chr17:7,005,530...7,050,179
Ensembl chr17:7,005,440...7,050,183
JBrowse link
G Fabp1 fatty acid binding protein 1, liver increases expression ISO Clozapine results in increased expression of FABP1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 6:71,176,863...71,182,018
Ensembl chr 6:71,176,811...71,182,007
JBrowse link
G Fan1 FANCD2/FANCI-associated nuclease 1 increases expression ISO Clozapine results in increased expression of FAN1 protein CTD PMID:34122009 NCBI chr 7:63,994,627...64,023,874
Ensembl chr 7:63,996,506...64,023,843
JBrowse link
G Farsa phenylalanyl-tRNA synthetase, alpha subunit increases expression ISO Clozapine results in increased expression of FARSA protein CTD PMID:34122009 NCBI chr 8:85,583,597...85,595,886
Ensembl chr 8:85,583,618...85,595,886
JBrowse link
G Farsb phenylalanyl-tRNA synthetase, beta subunit increases expression ISO Clozapine results in increased expression of FARSB protein CTD PMID:34122009 NCBI chr 1:78,394,595...78,465,534
Ensembl chr 1:78,394,612...78,465,534
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) multiple interactions EXP [Clozapine co-treated with Berberine] results in decreased expression of FAS mRNA CTD PMID:20564506 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) multiple interactions ISO [Clozapine analog co-treated with Hydrogen Peroxide] results in increased expression of FASLG mRNA; [Clozapine co-treated with Hydrogen Peroxide co-treated with Tretinoin] results in increased expression of FASLG mRNA CTD PMID:16510162 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Fasn fatty acid synthase increases expression ISO Clozapine results in increased expression of FASN mRNA CTD PMID:16027736 PMID:17052361 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Fdps farnesyl diphosphate synthetase increases expression ISO Clozapine results in increased expression of FDPS mRNA CTD PMID:17052361 NCBI chr 3:89,000,895...89,009,274
Ensembl chr 3:89,000,895...89,009,266
JBrowse link
G Fen1 flap structure specific endonuclease 1 increases expression ISO Clozapine results in increased expression of FEN1 protein CTD PMID:34122009 NCBI chr19:10,176,496...10,181,757
Ensembl chr19:10,176,496...10,181,533
JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression ISO Clozapine results in increased expression of FGF2 mRNA CTD PMID:11264663 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257
JBrowse link
G Fhod1 formin homology 2 domain containing 1 decreases expression ISO Clozapine results in decreased expression of FHOD1 protein CTD PMID:34122009 NCBI chr 8:106,055,792...106,074,650
Ensembl chr 8:106,055,795...106,074,585
JBrowse link
G Fkbp8 FK506 binding protein 8 decreases expression ISO Clozapine results in decreased expression of FKBP8 protein CTD PMID:34122009 NCBI chr 8:70,980,371...70,987,978
Ensembl chr 8:70,980,374...70,987,978
JBrowse link
G Flot2 flotillin 2 increases expression ISO Clozapine results in increased expression of FLOT2 protein CTD PMID:34122009 NCBI chr11:77,928,757...77,951,260
Ensembl chr11:77,928,757...77,951,260
JBrowse link
G Fmo1 flavin containing monooxygenase 1 increases metabolic processing ISO FMO1 protein results in increased metabolism of Clozapine CTD PMID:18809730 NCBI chr 1:162,657,130...162,694,179
Ensembl chr 1:162,657,130...162,694,179
JBrowse link
G Fmo3 flavin containing monooxygenase 3 increases metabolic processing ISO FMO3 protein results in increased metabolism of Clozapine CTD PMID:18809730 PMID:27320963 NCBI chr 1:162,781,368...162,812,097
Ensembl chr 1:162,781,369...162,812,097
JBrowse link
G Fndc4 fibronectin type III domain containing 4 increases expression ISO Clozapine results in increased expression of FNDC4 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 5:31,449,586...31,453,279
Ensembl chr 5:31,449,586...31,453,424
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions
increases expression
decreases expression
ISO
EXP
Clozapine affects the reaction [Haloperidol results in increased expression of FOS protein]; Cycloserine promotes the reaction [Clozapine results in increased expression of FOS mRNA]
Clozapine results in increased expression of FOS protein
Clozapine analog results in increased expression of FOS protein; Clozapine results in increased expression of FOS mRNA; Clozapine results in increased expression of FOS protein
Clozapine results in decreased expression of FOS protein
CTD PMID:10435392 PMID:11166331 PMID:11440804 PMID:11997696 PMID:12093589 More... NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Fosb FBJ osteosarcoma oncogene B increases expression
multiple interactions
decreases expression
EXP
ISO
Clozapine results in increased expression of FOSB protein alternative form
Clozapine results in increased expression of FOSB mRNA; Clozapine results in increased expression of FOSB protein
DRD3 protein affects the reaction [Clozapine results in increased expression of FOSB protein alternative form]
Clozapine results in decreased expression of FOSB mRNA
CTD PMID:11259127 PMID:12093589 PMID:12243769 PMID:15579174 PMID:19695244 NCBI chr 7:19,036,621...19,043,970
Ensembl chr 7:19,036,621...19,043,976
JBrowse link
G Fosl1 fos-like antigen 1 increases expression ISO Clozapine results in increased expression of FOSL1 mRNA CTD PMID:18208916 NCBI chr19:5,497,726...5,505,966
Ensembl chr19:5,497,575...5,505,974
JBrowse link
G Fosl2 fos-like antigen 2 increases expression ISO Clozapine results in increased expression of FOSL2 mRNA CTD PMID:12093589 PMID:12243769 NCBI chr 5:32,292,599...32,315,184
Ensembl chr 5:32,293,145...32,315,186
JBrowse link
G Foxp2 forkhead box P2 increases expression EXP Clozapine results in increased expression of FOXP2 mRNA CTD PMID:17266109 NCBI chr 6:14,901,348...15,441,976
Ensembl chr 6:14,901,348...15,441,976
JBrowse link
G Fstl1 follistatin-like 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of FSTL1 protein CTD PMID:34122009 NCBI chr16:37,597,417...37,656,878
Ensembl chr16:37,597,235...37,656,876
JBrowse link
G Fubp1 far upstream element (FUSE) binding protein 1 increases expression ISO Clozapine results in increased expression of FUBP1 protein CTD PMID:34122009 NCBI chr 3:151,916,059...151,942,467
Ensembl chr 3:151,916,059...151,942,463
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked decreases expression ISO Clozapine results in decreased expression of G6PD protein CTD PMID:34122009 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800
JBrowse link
G Gabbr1 gamma-aminobutyric acid (GABA) B receptor, 1 decreases expression EXP Clozapine results in decreased expression of GABBR1 mRNA CTD PMID:17266109 NCBI chr17:37,356,858...37,385,197
Ensembl chr17:37,356,858...37,385,959
JBrowse link
G Gabra1 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 increases expression EXP Clozapine results in increased expression of GABRA1 mRNA CTD PMID:17266109 NCBI chr11:42,021,766...42,073,893
Ensembl chr11:42,021,766...42,073,757
JBrowse link
G Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 increases expression ISO Clozapine results in increased expression of GABRB3 mRNA CTD PMID:18923069 NCBI chr 7:57,240,266...57,478,550
Ensembl chr 7:57,069,440...57,478,550
JBrowse link
G Gad1 glutamate decarboxylase 1 increases expression
decreases methylation
multiple interactions
ISO
EXP
Clozapine results in increased expression of GAD1 mRNA
Clozapine results in decreased methylation of GAD1 promoter
Clozapine promotes the reaction [KMT2A protein binds to GAD1 promoter]; Valproic Acid promotes the reaction [Clozapine results in decreased methylation of GAD1 promoter]
CTD PMID:12887421 PMID:15061247 PMID:17942719 PMID:18757738 PMID:18923069 NCBI chr 2:70,391,644...70,432,358
Ensembl chr 2:70,383,416...70,432,358
JBrowse link
G Gad2 glutamic acid decarboxylase 2 increases expression EXP
ISO
Clozapine results in increased expression of GAD2 mRNA CTD PMID:17266109 PMID:18923069 NCBI chr 2:22,512,262...22,583,889
Ensembl chr 2:22,512,217...22,583,886
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO Clozapine results in increased expression of GAPDH mRNA
Clozapine results in increased expression of GAPDH protein
CTD PMID:15860345 PMID:34122009 NCBI chr 6:125,138,815...125,143,430
Ensembl chr 6:125,138,678...125,143,430
JBrowse link
G Gart phosphoribosylglycinamide formyltransferase increases expression ISO Clozapine results in increased expression of GART protein CTD PMID:34122009 NCBI chr16:91,418,283...91,444,505
Ensembl chr16:91,418,074...91,443,840
JBrowse link
G Gatm glycine amidinotransferase (L-arginine:glycine amidinotransferase) increases expression ISO Clozapine results in increased expression of GATM protein CTD PMID:34122009 NCBI chr 2:122,424,954...122,441,758
Ensembl chr 2:122,424,948...122,441,784
JBrowse link
G Gcc2 GRIP and coiled-coil domain containing 2 decreases expression ISO Clozapine results in decreased expression of GCC2 protein CTD PMID:34122009 NCBI chr10:58,091,217...58,141,421
Ensembl chr10:58,091,319...58,141,421
JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO Clozapine results in increased expression of GDPD3 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 7:126,365,586...126,374,817
Ensembl chr 7:126,365,506...126,374,821
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression
increases expression
ISO Clozapine results in decreased expression of GFAP protein
Clozapine results in increased expression of GFAP mRNA
CTD PMID:18585900 PMID:19441803 NCBI chr11:102,778,162...102,791,368
Ensembl chr11:102,778,162...102,791,738
JBrowse link
G Ghitm growth hormone inducible transmembrane protein increases expression ISO Clozapine results in increased expression of GHITM protein CTD PMID:34122009 NCBI chr14:36,842,401...36,857,279
Ensembl chr14:36,842,049...36,857,229
JBrowse link
G Gimap5 GTPase, IMAP family member 5 decreases expression ISO Clozapine results in decreased expression of GIMAP5 mRNA CTD PMID:16715494 NCBI chr 6:48,723,131...48,731,134
Ensembl chr 6:48,723,131...48,731,144
JBrowse link
G Gip gastric inhibitory polypeptide increases expression ISO Clozapine results in increased expression of GIP mRNA; Clozapine results in increased expression of GIP protein CTD PMID:16402076 NCBI chr11:95,915,358...95,921,657
Ensembl chr11:95,915,371...95,921,657
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression ISO Clozapine results in increased expression of GJA1 protein CTD PMID:18585900 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609
JBrowse link
G Glrx3 glutaredoxin 3 increases expression ISO Clozapine results in increased expression of GLRX3 protein CTD PMID:34122009 NCBI chr 7:137,039,302...137,071,360
Ensembl chr 7:137,039,343...137,070,323
JBrowse link
G Gm4779 predicted gene 4779 increases expression ISO Clozapine results in increased expression of CXORF49 protein CTD PMID:34122009 NCBI chr  X:100,833,938...100,838,074
Ensembl chr  X:100,833,659...100,838,029
JBrowse link
G Gna12 guanine nucleotide binding protein, alpha 12 decreases expression
increases expression
ISO Clozapine results in decreased expression of GNA12 mRNA
Clozapine results in increased expression of GNA12 protein
CTD PMID:15860345 PMID:34122009 NCBI chr 5:140,745,699...140,816,186
Ensembl chr 5:140,744,163...140,816,186
JBrowse link
G Gnai1 guanine nucleotide binding protein (G protein), alpha inhibiting 1 decreases expression ISO Clozapine results in decreased expression of GNAI1 mRNA CTD PMID:15860345 NCBI chr 5:18,470,133...18,565,411
Ensembl chr 5:18,470,133...18,565,353
JBrowse link
G Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 decreases expression ISO Clozapine results in decreased expression of GNAI2 mRNA CTD PMID:15860345 NCBI chr 9:107,491,324...107,512,617
Ensembl chr 9:107,491,324...107,512,566
JBrowse link
G Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 decreases expression ISO Clozapine results in decreased expression of GNAI3 mRNA CTD PMID:15860345 NCBI chr 3:108,014,591...108,053,468
Ensembl chr 3:108,014,596...108,053,462
JBrowse link
G Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus decreases expression
increases expression
multiple interactions
ISO Clozapine results in decreased expression of GNAS mRNA
Clozapine results in increased expression of GNAS protein
[Cuprizone co-treated with Clozapine] results in decreased expression of GNAS protein
CTD PMID:15860345 PMID:34122009 NCBI chr 2:174,126,113...174,188,537
Ensembl chr 2:174,126,113...174,188,537
JBrowse link
G Gnb3 guanine nucleotide binding protein (G protein), beta 3 decreases response to substance
increases expression
affects response to substance
increases response to substance
ISO GNB3 gene polymorphism results in decreased susceptibility to Clozapine
Clozapine results in increased expression of GNB3 protein
GNB3 protein affects the susceptibility to Clozapine
GNB3 gene polymorphism results in increased susceptibility to Clozapine
CTD PMID:16139171 PMID:16141801 PMID:18855531 NCBI chr 6:124,811,203...124,817,238
Ensembl chr 6:124,811,203...124,817,238
JBrowse link
G Golga3 golgi autoantigen, golgin subfamily a, 3 increases expression ISO Clozapine results in increased expression of GOLGA3 protein CTD PMID:34122009 NCBI chr 5:110,324,723...110,374,336
Ensembl chr 5:110,324,567...110,374,336
JBrowse link
G Golgb1 golgi autoantigen, golgin subfamily b, macrogolgin 1 increases expression ISO Clozapine results in increased expression of GOLGB1 protein CTD PMID:34122009 NCBI chr16:36,695,455...36,753,447
Ensembl chr16:36,695,502...36,753,447
JBrowse link
G Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial increases expression
multiple interactions
ISO Clozapine results in increased expression of GOT2 mRNA
[Cuprizone co-treated with Clozapine] results in increased expression of GOT2 protein
CTD PMID:15860345 PMID:34122009 NCBI chr 8:96,590,761...96,615,029
Ensembl chr 8:96,590,762...96,615,175
JBrowse link
G Gpd2 glycerol phosphate dehydrogenase 2, mitochondrial decreases expression ISO Clozapine results in decreased expression of GPD2 protein CTD PMID:34122009 NCBI chr 2:57,127,690...57,260,731
Ensembl chr 2:57,127,647...57,260,731
JBrowse link
G Gpi1 glucose-6-phosphate isomerase 1 increases expression ISO Clozapine results in increased expression of GPI protein CTD PMID:34122009 NCBI chr 7:33,900,752...33,929,761
Ensembl chr 7:33,900,755...33,929,761
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression EXP Clozapine results in increased expression of GPX1 mRNA CTD PMID:14647396 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Grik2 glutamate receptor, ionotropic, kainate 2 (beta 2) increases expression ISO Clozapine results in increased expression of GRIK2 mRNA CTD PMID:18923069 NCBI chr10:48,969,776...49,666,523
Ensembl chr10:48,970,929...49,664,862
JBrowse link
G Grik5 glutamate receptor, ionotropic, kainate 5 (gamma 2) affects expression
decreases expression
EXP
ISO
Clozapine affects the expression of GRIK5 mRNA
Clozapine results in decreased expression of GRIK5 mRNA
CTD PMID:14647396 PMID:18923069 NCBI chr 7:24,709,274...24,775,421
Ensembl chr 7:24,709,274...24,771,771
JBrowse link
G Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) decreases expression
increases expression
EXP
ISO
Clozapine results in decreased expression of GRIN1 mRNA
Clozapine results in increased expression of GRIN1 mRNA
CTD PMID:12020038 PMID:12608697 PMID:17266109 PMID:18923069 NCBI chr 2:25,181,189...25,209,199
Ensembl chr 2:25,181,193...25,209,199
JBrowse link
G Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) decreases expression ISO Clozapine results in decreased expression of GRIN2A mRNA CTD PMID:12608697 PMID:18923069 NCBI chr16:9,385,765...9,813,744
Ensembl chr16:9,385,762...9,813,424
JBrowse link
G Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) decreases expression ISO Clozapine results in decreased expression of GRIN2B mRNA CTD PMID:18923069 NCBI chr 6:135,690,219...136,150,658
Ensembl chr 6:135,690,231...136,150,509
JBrowse link
G Grin2c glutamate receptor, ionotropic, NMDA2C (epsilon 3) decreases expression ISO Clozapine results in decreased expression of GRIN2C mRNA CTD PMID:18923069 NCBI chr11:115,139,995...115,158,123
Ensembl chr11:115,139,995...115,158,069
JBrowse link
G Grk6 G protein-coupled receptor kinase 6 decreases expression ISO Clozapine results in decreased expression of GRK6 mRNA CTD PMID:16715494 NCBI chr13:55,592,865...55,608,740
Ensembl chr13:55,592,885...55,608,740
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha increases expression
multiple interactions
ISO Clozapine results in increased expression of GSK3A protein
DRD2 protein affects the reaction [Clozapine results in increased expression of GSK3A protein]
CTD PMID:16144542 NCBI chr 7:24,927,683...24,937,276
Ensembl chr 7:24,927,683...24,937,276
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation
increases expression
multiple interactions
ISO Clozapine results in increased phosphorylation of GSK3B protein
Clozapine results in increased expression of GSK3B protein
DRD2 protein affects the reaction [Clozapine results in increased expression of GSK3B protein]
CTD PMID:16144542 PMID:19359144 PMID:19440698 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 decreases activity
increases expression
increases glutathionylation
ISO GSTM1 protein results in decreased activity of Clozapine
Clozapine results in increased expression of GSTM1 mRNA
GSTM1 protein results in increased glutathionylation of Clozapine
CTD PMID:15860345 PMID:20849150 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
JBrowse link
G Gstm2 glutathione S-transferase, mu 2 decreases expression ISO Clozapine results in decreased expression of GSTM2 mRNA CTD PMID:15860345 NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 increases glutathionylation
affects metabolic processing
affects binding
decreases activity
ISO GSTP1 protein results in increased glutathionylation of Clozapine
GSTP1 protein affects the metabolism of Clozapine metabolite
Clozapine metabolite binds to GSTP1 protein
Clozapine metabolite results in decreased activity of GSTP1 protein; GSTP1 protein results in decreased activity of Clozapine
CTD PMID:20849150 PMID:21639118 PMID:24185126 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO Clozapine results in increased expression of H1-2 protein CTD PMID:34122009 NCBI chr13:23,922,790...23,923,514
Ensembl chr13:23,922,791...23,924,350
JBrowse link
G H2ac18 H2A clustered histone 18 increases expression EXP Clozapine results in increased expression of H2AC18 mRNA CTD PMID:14647396 NCBI chr 3:96,152,813...96,153,368
Ensembl chr 3:96,152,813...96,153,398
JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 increases expression ISO Clozapine results in increased expression of HACD3 protein CTD PMID:34122009 NCBI chr 9:64,894,265...64,929,014
Ensembl chr 9:64,894,265...64,928,975
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression ISO Clozapine results in increased expression of HADHB protein CTD PMID:34122009 NCBI chr 5:30,360,251...30,389,591
Ensembl chr 5:30,360,246...30,389,591
JBrowse link
G Hars histidyl-tRNA synthetase increases expression ISO Clozapine results in increased expression of HARS protein CTD PMID:34122009 NCBI chr18:36,899,581...36,916,258
Ensembl chr18:36,899,581...36,916,258
JBrowse link
G Hat1 histone aminotransferase 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of HAT1 protein CTD PMID:34122009 NCBI chr 2:71,219,604...71,271,966
Ensembl chr 2:71,219,302...71,271,966
JBrowse link
G Hcls1 hematopoietic cell specific Lyn substrate 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of HCLS1 protein CTD PMID:34122009 NCBI chr16:36,755,345...36,783,576
Ensembl chr16:36,755,345...36,783,574
JBrowse link
G Hdgfl2 HDGF like 2 increases expression ISO Clozapine results in increased expression of HDGFRP2 protein CTD PMID:34122009 NCBI chr17:56,386,601...56,407,605
Ensembl chr17:56,386,634...56,407,607
JBrowse link
G Higd1a HIG1 domain family, member 1A increases expression EXP Clozapine results in increased expression of HIGD1A mRNA CTD PMID:14647396 NCBI chr 9:121,677,623...121,686,862
Ensembl chr 9:121,677,629...121,687,428
JBrowse link
G Hmgb2 high mobility group box 2 increases expression ISO Clozapine results in increased expression of HMGB2 protein CTD PMID:34122009 NCBI chr 8:57,964,877...57,969,033
Ensembl chr 8:57,964,941...57,969,033
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase multiple interactions
increases expression
increases activity
ISO [Clozapine results in increased activity of HMGCR protein] which results in increased abundance of Cholesterol; [Clozapine results in increased activity of HMGCR protein] which results in increased abundance of Triglycerides
Clozapine results in increased expression of HMGCR mRNA
CTD PMID:16027736 PMID:17052361 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 increases expression ISO Clozapine results in increased expression of HMGCS1 mRNA CTD PMID:16027736 PMID:17052361 NCBI chr13:120,151,887...120,169,796
Ensembl chr13:120,151,915...120,169,796
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Clozapine results in increased expression of HMOX1 mRNA CTD PMID:18227147 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D decreases expression ISO Clozapine results in decreased expression of HNRNPD protein CTD PMID:34122009 NCBI chr 5:100,103,794...100,126,926
Ensembl chr 5:100,103,794...100,126,797
JBrowse link
G Homer1 homer scaffolding protein 1 increases expression
multiple interactions
ISO Clozapine results in increased expression of HOMER1 mRNA
Cycloserine inhibits the reaction [Clozapine results in increased expression of HOMER1 mRNA]
CTD PMID:12464447 PMID:15860345 NCBI chr13:93,440,265...93,549,471
Ensembl chr13:93,436,143...93,541,637
JBrowse link
G Hpcal1 hippocalcin-like 1 decreases expression ISO Clozapine results in decreased expression of HPCAL1 mRNA CTD PMID:12437575 NCBI chr12:17,740,793...17,841,943
Ensembl chr12:17,740,857...17,841,934
JBrowse link
G Hpcal4 hippocalcin-like 4 affects expression ISO Clozapine affects the expression of HPCAL4 mRNA CTD PMID:12437575 NCBI chr 4:123,077,297...123,088,492
Ensembl chr 4:123,077,020...123,088,494
JBrowse link
G Hpn hepsin increases expression ISO Clozapine results in increased expression of HPN mRNA CTD PMID:15342952 NCBI chr 7:30,798,150...30,814,751
Ensembl chr 7:30,798,150...30,814,715
JBrowse link
G Hrh1 histamine receptor H1 affects binding ISO Clozapine binds to HRH1 protein CTD PMID:16983399 NCBI chr 6:114,374,897...114,460,259
Ensembl chr 6:114,374,897...114,460,257
JBrowse link
G Hrh3 histamine receptor H3 multiple interactions ISO Clozapine binds to Hrh3 protein; Clozapine inhibits the reaction [N-methylhistamine binds to Hrh3 protein] RGD PMID:10869375 RGD:632981 NCBI chr 2:179,741,258...179,746,293
Ensembl chr 2:179,741,258...179,746,281
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 decreases expression ISO Clozapine results in decreased expression of HSD17B10 protein CTD PMID:34122009 NCBI chr  X:150,784,892...150,787,438
Ensembl chr  X:150,784,841...150,787,438
JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 increases expression ISO Clozapine results in increased expression of HSD17B12 protein CTD PMID:34122009 NCBI chr 2:93,863,042...93,988,254
Ensembl chr 2:93,863,034...93,988,309
JBrowse link
G Hspa9 heat shock protein 9 decreases expression ISO Clozapine results in decreased expression of HSPA9 protein CTD PMID:34122009 NCBI chr18:35,070,467...35,087,404
Ensembl chr18:35,070,467...35,087,410
JBrowse link
G Htr1a 5-hydroxytryptamine (serotonin) receptor 1A multiple interactions
affects binding
ISO Clozapine binds to and affects the activity of HTR1A protein
Clozapine binds to HTR1A protein
CTD PMID:9723970 PMID:15482641 NCBI chr13:105,580,201...105,584,641
Ensembl chr13:105,580,147...105,584,630
JBrowse link
G Htr1d 5-hydroxytryptamine (serotonin) receptor 1D decreases expression ISO Clozapine results in decreased expression of HTR1D mRNA CTD PMID:16715494 NCBI chr 4:136,150,829...136,176,284
Ensembl chr 4:136,150,835...136,171,709
JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A increases response to substance
affects binding
multiple interactions
decreases expression
decreases activity
affects response to substance
increases expression
ISO
EXP
HTR2A gene SNP results in increased susceptibility to Clozapine
Clozapine analog binds to HTR2A protein; Clozapine binds to HTR2A protein
Clozapine binds to and results in decreased activity of HTR2A protein; Clozapine inhibits the reaction [Ketanserin binds to HTR2A protein]
Clozapine results in decreased expression of HTR2A mRNA; Clozapine results in decreased expression of HTR2A protein
Clozapine results in decreased activity of HTR2A protein
[[Clozapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein] which results in increased expression of RGS7 protein; [Clozapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [[[Clozapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein] which results in increased expression of RGS7 protein]; Clozapine binds to and results in decreased activity of HTR2A protein; Clozapine promotes the reaction [Phencyclidine results in decreased activity of HTR2A protein]
HTR2A protein affects the susceptibility to Clozapine
Clozapine results in increased expression of HTR2A mRNA
CTD PMID:7520908 PMID:9723970 PMID:11997696 PMID:14751426 PMID:15380371 More... NCBI chr14:74,878,314...74,944,299
Ensembl chr14:74,878,280...74,946,934
JBrowse link
G Htr2c 5-hydroxytryptamine (serotonin) receptor 2C affects binding
decreases expression
affects response to substance
ISO Clozapine binds to HTR2C protein
Clozapine results in decreased expression of HTR2C mRNA
HTR2C gene polymorphism affects the susceptibility to Clozapine; HTR2C gene SNP affects the susceptibility to Clozapine; HTR2C promoter SNP affects the susceptibility to Clozapine; HTR2C protein affects the susceptibility to Clozapine
CTD PMID:9723970 PMID:12668355 PMID:15635667 PMID:16983399 PMID:17868938 More... NCBI chr  X:145,745,509...145,980,273
Ensembl chr  X:145,745,509...145,980,273
JBrowse link
G Htr3a 5-hydroxytryptamine (serotonin) receptor 3A multiple interactions
affects response to substance
ISO
EXP
Clozapine binds to and results in decreased activity of HTR3A protein
HTR3A protein affects the susceptibility to Clozapine
CTD PMID:19696922 PMID:20168265 NCBI chr 9:48,810,513...48,822,451
Ensembl chr 9:48,810,513...48,822,399
JBrowse link
G Htr6 5-hydroxytryptamine (serotonin) receptor 6 multiple interactions
affects binding
EXP
ISO
Clozapine binds to and results in decreased activity of HTR6 protein
[Cuprizone co-treated with Clozapine] results in increased expression of HTR6 protein
Clozapine binds to HTR6 protein
CTD PMID:11406289 PMID:16983399 PMID:34122009 NCBI chr 4:138,787,017...138,802,881
Ensembl chr 4:138,788,419...138,802,881
JBrowse link
G Htr7 5-hydroxytryptamine (serotonin) receptor 7 affects binding
multiple interactions
ISO Clozapine binds to HTR7 protein
[Clozapine binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; Clozapine inhibits the reaction [Risperidone binds to and results in decreased activity of HTR7 protein]
CTD PMID:14578406 PMID:20827463 NCBI chr19:35,935,815...36,035,533
Ensembl chr19:35,936,134...36,034,907
JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression ISO Clozapine results in increased expression of ID2 mRNA CTD PMID:12437575 NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139
JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of IDH2 protein CTD PMID:34122009 NCBI chr 7:79,744,594...79,768,356
Ensembl chr 7:79,744,594...79,765,140
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase decreases expression ISO Clozapine results in decreased expression of IDI1 protein CTD PMID:34122009 NCBI chr13:8,935,642...8,942,432
Ensembl chr13:8,935,537...8,942,487
JBrowse link
G Ifng interferon gamma affects expression
decreases expression
ISO Clozapine affects the expression of IFNG protein
Clozapine results in decreased expression of IFNG mRNA
CTD PMID:17346280 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression ISO Clozapine results in decreased expression of IGF1 protein CTD PMID:11769361 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
JBrowse link
G Il10 interleukin 10 decreases expression ISO Clozapine results in decreased expression of IL10 protein CTD PMID:24709159 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il1b interleukin 1 beta increases secretion
multiple interactions
ISO Clozapine results in increased secretion of IL1B protein
belnacasan inhibits the reaction [Clozapine results in increased secretion of IL1B protein]
CTD PMID:34935985 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il2ra interleukin 2 receptor, alpha chain increases secretion ISO Clozapine results in increased secretion of IL2RA protein CTD PMID:8067274 NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004
JBrowse link
G Il5 interleukin 5 affects expression ISO Clozapine affects the expression of IL5 protein CTD PMID:17346280 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
JBrowse link
G Ilkap integrin-linked kinase-associated serine/threonine phosphatase 2C decreases expression ISO Clozapine results in decreased expression of ILKAP mRNA CTD PMID:15860345 NCBI chr 1:91,301,568...91,326,566
Ensembl chr 1:91,301,583...91,326,537
JBrowse link
G Inha inhibin alpha decreases expression ISO Clozapine results in decreased expression of INHA mRNA CTD PMID:16715494 NCBI chr 1:75,483,721...75,487,010
Ensembl chr 1:75,483,721...75,487,010
JBrowse link
G Inhbe inhibin beta-E increases expression ISO Clozapine results in increased expression of INHBE mRNA CTD PMID:15342952 PMID:17175557 NCBI chr10:127,185,271...127,187,717
Ensembl chr10:127,184,726...127,190,280
JBrowse link
G Ins2 insulin II affects secretion
increases expression
ISO Clozapine affects the secretion of INS protein
Clozapine results in increased expression of INS protein
CTD PMID:11769361 PMID:16601995 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
JBrowse link
G Itga6 integrin alpha 6 increases expression ISO Clozapine results in increased expression of ITGA6 protein CTD PMID:34122009 NCBI chr 2:71,617,236...71,688,771
Ensembl chr 2:71,575,960...71,688,760
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO [[Clozapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein] which results in increased expression of RGS7 protein; [Clozapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [[[Clozapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein] which results in increased expression of RGS7 protein] CTD PMID:18976543 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480
JBrowse link
G Jun jun proto-oncogene decreases expression
increases expression
ISO Clozapine results in decreased expression of JUN mRNA
Clozapine results in increased expression of JUN mRNA
CTD PMID:12093589 PMID:15860345 PMID:18208916 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Junb jun B proto-oncogene increases expression ISO Clozapine results in increased expression of JUNB mRNA CTD PMID:12093589 PMID:19695244 NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347
JBrowse link
G Jund jun D proto-oncogene decreases expression ISO Clozapine results in decreased expression of JUND mRNA CTD PMID:12093589 NCBI chr 8:71,150,389...71,153,265
Ensembl chr 8:71,151,599...71,153,265
JBrowse link
G Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 increases expression EXP Clozapine results in increased expression of KCNA1 mRNA CTD PMID:18797397 NCBI chr 6:126,613,426...126,622,764
Ensembl chr 6:126,617,360...126,623,347
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 multiple interactions ISO Clozapine inhibits the reaction [KCNH2 protein results in increased transport of Thallium] CTD PMID:21158687 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
G Kcnip3 Kv channel interacting protein 3, calsenilin decreases expression
increases expression
EXP Clozapine results in decreased expression of KCNIP3 mRNA
Clozapine results in increased expression of KCNIP3 mRNA
CTD PMID:17266109 PMID:18797397 NCBI chr 2:127,298,418...127,364,014
Ensembl chr 2:127,298,418...127,364,014
JBrowse link
G Kcnk2 potassium channel, subfamily K, member 2 decreases expression EXP Clozapine results in decreased expression of KCNK2 mRNA CTD PMID:15542763 NCBI chr 1:188,940,127...189,134,979
Ensembl chr 1:188,940,127...189,134,470
JBrowse link
G Kctd12 potassium channel tetramerisation domain containing 12 decreases expression ISO Clozapine results in decreased expression of KCTD12 protein CTD PMID:34122009 NCBI chr14:103,214,017...103,220,073
Ensembl chr14:103,214,017...103,220,073
JBrowse link
G Kdr kinase insert domain protein receptor increases expression ISO Clozapine results in increased expression of KDR protein CTD PMID:34122009 NCBI chr 5:76,093,487...76,139,885
Ensembl chr 5:76,093,487...76,139,118
JBrowse link
G Khdrbs1 KH domain containing, RNA binding, signal transduction associated 1 decreases expression ISO Clozapine results in decreased expression of KHDRBS1 protein CTD PMID:34122009 NCBI chr 4:129,596,143...129,637,402
Ensembl chr 4:129,596,957...129,636,096
JBrowse link
G Kif13b kinesin family member 13B increases expression ISO Clozapine results in increased expression of KIF13B protein CTD PMID:34122009 NCBI chr14:64,889,633...65,047,067
Ensembl chr14:64,884,714...65,047,066
JBrowse link
G Kif5c kinesin family member 5C decreases expression ISO Clozapine results in decreased expression of KIF5C protein CTD PMID:34122009 NCBI chr 2:49,509,298...49,664,790
Ensembl chr 2:49,509,310...49,664,790
JBrowse link
G Kiz kizuna centrosomal protein multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of KIZ protein CTD PMID:34122009 NCBI chr 2:146,697,743...146,812,018
Ensembl chr 2:146,697,784...146,812,017
JBrowse link
G Klhdc2 kelch domain containing 2 decreases expression ISO Clozapine results in decreased expression of KLHDC2 protein CTD PMID:34122009 NCBI chr12:69,343,455...69,357,461
Ensembl chr12:69,343,455...69,357,461
JBrowse link
G Kmt2a lysine (K)-specific methyltransferase 2A increases expression
decreases expression
multiple interactions
ISO
EXP
Clozapine results in increased expression of KMT2A mRNA
Clozapine results in decreased expression of KMT2A mRNA
Clozapine promotes the reaction [KMT2A protein binds to GAD1 promoter]
CTD PMID:14647396 PMID:17942719 NCBI chr 9:44,714,652...44,793,492
Ensembl chr 9:44,714,652...44,792,594
JBrowse link
G Kpna4 karyopherin (importin) alpha 4 multiple interactions
increases expression
ISO [Cuprizone co-treated with Clozapine] results in increased expression of KPNA4 protein
Clozapine results in increased expression of KPNA4 protein
CTD PMID:34122009 NCBI chr 3:68,979,554...69,034,425
Ensembl chr 3:68,974,482...69,034,446
JBrowse link
G Kremen1 kringle containing transmembrane protein 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of KREMEN1 protein CTD PMID:34122009 NCBI chr11:5,141,551...5,212,220
Ensembl chr11:5,141,552...5,211,558
JBrowse link
G Lactb2 lactamase, beta 2 increases expression ISO Clozapine results in increased expression of LACTB2 protein CTD PMID:34122009 NCBI chr 1:13,696,117...13,731,424
Ensembl chr 1:13,693,554...13,730,770
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 increases expression ISO Clozapine results in increased expression of LAMP1 protein CTD PMID:34122009 NCBI chr 8:13,209,161...13,225,338
Ensembl chr 8:13,209,161...13,225,338
JBrowse link
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 increases expression EXP Clozapine results in increased expression of LAMTOR3 mRNA CTD PMID:14647396 NCBI chr 3:137,624,316...137,634,523
Ensembl chr 3:137,624,267...137,634,661
JBrowse link
G Larp7 La ribonucleoprotein 7, transcriptional regulator increases expression ISO Clozapine results in increased expression of LARP7 protein CTD PMID:34122009 NCBI chr 3:127,330,363...127,346,998
Ensembl chr 3:127,330,363...127,346,998
JBrowse link
G Lcn3 lipocalin 3 decreases expression ISO Clozapine results in decreased expression of LCN1 protein CTD PMID:34122009 NCBI chr 2:25,655,545...25,658,110
Ensembl chr 2:25,655,581...25,658,111
JBrowse link
G Ldhb lactate dehydrogenase B increases expression ISO Clozapine results in increased expression of LDHB mRNA CTD PMID:15860345 NCBI chr 6:142,435,975...142,453,683
Ensembl chr 6:142,435,975...142,453,683
JBrowse link
G Ldlr low density lipoprotein receptor increases expression
multiple interactions
EXP
ISO
Clozapine results in increased expression of LDLR mRNA
Berberine inhibits the reaction [Clozapine results in increased expression of LDLR mRNA]
CTD PMID:17052361 PMID:20564506 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
G Leap2 liver-expressed antimicrobial peptide 2 increases expression ISO Clozapine results in increased expression of LEAP2 mRNA CTD PMID:17346280 NCBI chr11:53,313,008...53,313,963
Ensembl chr11:53,313,008...53,313,997
JBrowse link
G Lemd2 LEM domain containing 2 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of LEMD2 protein CTD PMID:34122009 NCBI chr17:27,408,574...27,426,228
Ensembl chr17:27,408,574...27,423,443
JBrowse link
G Lep leptin affects response to substance
increases expression
ISO LEP protein affects the susceptibility to Clozapine
Clozapine results in increased expression of LEP protein
CTD PMID:16402076 PMID:17502770 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Lipa lysosomal acid lipase A increases expression ISO Clozapine results in increased expression of LIPA protein CTD PMID:34122009 NCBI chr19:34,469,716...34,504,874
Ensembl chr19:34,469,718...34,504,874
JBrowse link
G Lmod2 leiomodin 2 (cardiac) increases expression ISO Clozapine results in increased expression of LMOD2 protein CTD PMID:34122009 NCBI chr 6:24,597,770...24,605,413
Ensembl chr 6:24,597,761...24,605,413
JBrowse link
G Lpl lipoprotein lipase decreases expression
increases expression
EXP Clozapine results in decreased expression of LPL mRNA; Clozapine results in decreased expression of LPL protein
Clozapine results in increased expression of LPL mRNA
CTD PMID:17266109 PMID:19682446 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
JBrowse link
G Lrpprc leucine-rich PPR-motif containing increases expression ISO Clozapine results in increased expression of LRPPRC protein CTD PMID:34122009 NCBI chr17:85,012,675...85,098,214
Ensembl chr17:85,012,675...85,098,217
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 increases expression ISO Clozapine results in increased expression of LRRK2 protein CTD PMID:34122009 NCBI chr15:91,556,994...91,700,327
Ensembl chr15:91,557,378...91,700,323
JBrowse link
G Lss lanosterol synthase increases expression
multiple interactions
ISO Clozapine results in increased expression of LSS mRNA
[Cuprizone co-treated with Clozapine] results in decreased expression of LSS protein
CTD PMID:15342952 PMID:17175557 PMID:34122009 NCBI chr10:76,367,303...76,392,973
Ensembl chr10:76,367,422...76,392,972
JBrowse link
G Lta4h leukotriene A4 hydrolase decreases expression ISO Clozapine results in decreased expression of LTA4H protein CTD PMID:34122009 NCBI chr10:93,289,258...93,320,758
Ensembl chr10:93,289,273...93,320,737
JBrowse link
G Magt1 magnesium transporter 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of MAGT1 protein CTD PMID:34122009 NCBI chr  X:105,011,690...105,055,408
Ensembl chr  X:105,011,690...105,055,512
JBrowse link
G Mal myelin and lymphocyte protein, T cell differentiation protein decreases expression EXP Clozapine results in decreased expression of MAL mRNA CTD PMID:17266109 PMID:18797397 NCBI chr 2:127,475,146...127,498,615
Ensembl chr 2:127,475,146...127,498,615
JBrowse link
G Maob monoamine oxidase B increases expression EXP Clozapine results in increased expression of MAOB mRNA CTD PMID:17266109 NCBI chr  X:16,575,520...16,683,605
Ensembl chr  X:16,575,521...16,683,605
JBrowse link
G Map1a microtubule-associated protein 1 A increases expression
decreases expression
ISO Clozapine results in increased expression of MAP1A mRNA
Clozapine results in decreased expression of MAP1A protein
CTD PMID:15860345 PMID:34122009 NCBI chr 2:121,119,608...121,141,313
Ensembl chr 2:121,120,081...121,141,313
JBrowse link
G Map1b microtubule-associated protein 1B decreases expression ISO Clozapine results in decreased expression of MAP1B protein CTD PMID:34122009 NCBI chr13:99,557,972...99,653,110
Ensembl chr13:99,557,954...99,653,048
JBrowse link
G Map1s microtubule-associated protein 1S increases expression ISO Clozapine results in increased expression of MAP1S protein CTD PMID:34122009 NCBI chr 8:71,358,618...71,370,173
Ensembl chr 8:71,358,576...71,370,173
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 decreases expression ISO Clozapine results in decreased expression of MAP2K1 mRNA CTD PMID:15860345 NCBI chr 9:64,093,051...64,160,887
Ensembl chr 9:64,093,052...64,160,913
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G Map2k2 mitogen-activated protein kinase kinase 2 increases expression
decreases expression
EXP
ISO
Clozapine results in increased expression of MAP2K2 mRNA
Clozapine results in decreased expression of MAP2K2 mRNA
CTD PMID:14647396 PMID:15860345 NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809
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G Map2k5 mitogen-activated protein kinase kinase 5 decreases expression ISO Clozapine results in decreased expression of MAP2K5 mRNA CTD PMID:15860345 NCBI chr 9:63,071,050...63,288,964
Ensembl chr 9:63,071,050...63,285,184
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression ISO Clozapine results in increased expression of MAP3K1 mRNA CTD PMID:15860345 NCBI chr13:111,882,962...111,954,803
Ensembl chr13:111,882,962...111,945,527
JBrowse link
G Map3k12 mitogen-activated protein kinase kinase kinase 12 increases expression ISO Clozapine results in increased expression of MAP3K12 mRNA CTD PMID:15860345 NCBI chr15:102,406,082...102,425,439
Ensembl chr15:102,406,081...102,425,499
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
decreases expression
decreases phosphorylation
EXP
ISO
Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]
Clozapine results in decreased expression of MAPK1 mRNA
Clozapine results in decreased phosphorylation of MAPK1 protein
CTD PMID:12871586 PMID:15860345 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 affects expression ISO Clozapine affects the expression of MAPK14 mRNA CTD PMID:15860345 NCBI chr17:28,910,243...28,967,379
Ensembl chr17:28,910,303...28,967,380
JBrowse link