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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:48525 term browser browse the term
Definition:A drug that it mimics the action of calcium on tissues.
Synonyms:related_synonym: calcimimetics

show annotations for term's descendants           Sort by:
cinacalcet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO Cinacalcet results in decreased activity of CYP2D6 protein CTD PMID:16680561 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Cinacalcet results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Pth parathyroid hormone decreases expression
decreases secretion
multiple interactions
ISO Cinacalcet results in decreased expression of PTH protein
Cinacalcet results in decreased secretion of PTH protein
[Cinacalcet co-treated with Vitamin D] results in decreased expression of PTH protein
CTD PMID:17060004, PMID:18256372, PMID:21541686, PMID:22118402 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19718
      application 19363
        pharmaceutical 19235
          drug 19235
            calcimimetic 3
              cinacalcet + 3
              cinacalcet hydrochloride 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.