Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

go back to main search page
Accession:CHEBI:48520 term browser browse the term
Definition:A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine which is substituted on the nitrogen by a 2-(2-naphthyl)ethyl group and at position 4 by a m-trifluoromethylphenyl group.
Synonyms:exact_synonym: 1-[2-(2-naphthyl)ethyl]-4-[3-(trifluoromethyl)phenyl]-1,2,3,6-tetrahydropyridine
 related_synonym: 1,2,3,6-tetrahydro-1-(2-(2-naphthalenyl)ethyl)-4-(3-(trifluoromethyl)phenyl)-pyridine;   1,2,3,6-tetrahydro-1-(2-(2-naphthyl)ethyl)-4-(alpha,alpha,alpha-trifluoro-m-tolyl)pyridine;   Formula=C24H22F3N;   InChI=1S/C24H22F3N/c25-24(26,27)23-7-3-6-22(17-23)20-11-14-28(15-12-20)13-10-18-8-9-19-4-1-2-5-21(19)16-18/h1-9,11,16-17H,10,12-15H2;   InChIKey=WJJYZXPHLSLMGE-UHFFFAOYSA-N;   SMILES=FC(F)(F)c1cccc(c1)C1=CCN(CCc2ccc3ccccc3c2)CC1
 xref: Beilstein:8164054;   CAS:135354-02-8;   Drug_Central:4367;   KEGG:D06327;   LINCS:LSM-3966
 xref_mesh: MESH:C462299
 xref: Patent:EP101381;   Patent:US4521428

show annotations for term's descendants           Sort by:
xaliproden term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions EXP xaliproden inhibits the reaction [Vincristine results in decreased expression of ACHE protein] CTD PMID:8413926 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO xaliproden results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19715
    role 19690
      biological role 19688
        pharmacological role 18940
          neurotransmitter agent 16594
            serotonergic drug 4264
              serotonergic agonist 983
                xaliproden 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19715
    subatomic particle 19713
      composite particle 19713
        hadron 19713
          baryon 19713
            nucleon 19713
              atomic nucleus 19713
                atom 19713
                  main group element atom 19662
                    main group molecular entity 19662
                      s-block molecular entity 19511
                        hydrogen molecular entity 19504
                          hydrides 18967
                            organic hydride 18581
                              organic fundamental parent 18581
                                hydrocarbon 18346
                                  halohydrocarbon 15361
                                    haloalkane 12091
                                      fluoroalkane 7755
                                        fluoromethanes 6700
                                          tetrafluoromethane 6700
                                            trifluoromethyl group 6700
                                              (trifluoromethyl)benzenes 6700
                                                xaliproden 2
paths to the root