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ONTOLOGY REPORT - ANNOTATIONS


Term:cinacalcet
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Accession:CHEBI:48390 term browser browse the term
Definition:A secondary amino compound that is (1R)-1-(naphthalen-1-yl)ethanamine in which one of the hydrogens attached to the nitrogen is substituted by a 3-[3-(trifluoromethyl)phenyl]propyl group.
Synonyms:exact_synonym: N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine
 related_synonym: (R)-alpha-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine;   CNC;   Formula=C22H22F3N;   InChI=1S/C22H22F3N/c1-16(20-13-5-10-18-9-2-3-12-21(18)20)26-14-6-8-17-7-4-11-19(15-17)22(23,24)25/h2-5,7,9-13,15-16,26H,6,8,14H2,1H3/t16-/m1/s1;   InChIKey=VDHAWDNDOKGFTD-MRXNPFEDSA-N;   Mimpara;   N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine;   SMILES=C[C@@H](NCCCc1cccc(c1)C(F)(F)F)c1cccc2ccccc12
 xref: CAS:226256-56-0 "ChemIDplus";   DrugBank:DB01012;   Drug_Central:647 "DrugCentral";   KEGG:D03504;   LINCS:LSM-5815
 xref_mesh: MESH:D000069449
 xref: PMID:16680561 "Europe PMC";   PMID:17652181 "Europe PMC";   Patent:US2007060645;   Patent:US6011068;   Patent:US6211244;   Reaxys:10191346 "Reaxys";   Wikipedia:Cinacalcet


show annotations for term's descendants       view all columns           Sort by:
 
cinacalcet term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Pth parathyroid hormone JBrowse link 1 178,215,829 178,218,761 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        pharmaceutical 19097
          drug 19097
            calcimimetic 3
              cinacalcet 3
                cinacalcet carbamate 0
                cinacalcet hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    main group molecular entity 19545
                      s-block molecular entity 19329
                        hydrogen molecular entity 19319
                          hydrides 18242
                            organic hydride 17528
                              organic fundamental parent 17528
                                hydrocarbon 16935
                                  alkane 12481
                                    methane 9407
                                      halomethane 9407
                                        fluoromethanes 6272
                                          fluoroform 6272
                                            trifluoromethyl group 6272
                                              (trifluoromethyl)benzenes 6272
                                                cinacalcet 3
                                                  cinacalcet carbamate 0
                                                  cinacalcet hydrochloride 0
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