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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:organic bromide salt
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Accession:CHEBI:48369 term browser browse the term
Synonyms:related_synonym: organic bromide salts



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3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity ISO thiazolyl blue results in decreased activity of ABCB1 protein CTD PMID:15451006 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Aco2 aconitase 2 multiple interactions ISO [Calcium results in increased activity of ACO2 protein] which results in increased reduction of thiazolyl blue; [Potassium deficiency results in decreased activity of ACO2 protein] which results in decreased reduction of thiazolyl blue CTD PMID:12548706 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Casp3 caspase 3 increases activity ISO thiazolyl blue results in increased activity of CASP3 protein CTD PMID:22401948 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity ISO thiazolyl blue results in increased activity of CASP8 protein CTD PMID:22401948 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 increases reduction
multiple interactions
ISO NQO2 protein results in increased reduction of thiazolyl blue
resveratrol inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue]; Tacrine inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue]
CTD PMID:29281794 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320
JBrowse link
butylscopolamine bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Butylscopolammonium Bromide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
NAN 190 hydrobromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP
ISO
[1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to Serotonin
[1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to Methamphetamine
CTD PMID:15213358 PMID:15482641 PMID:16528294 NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
tiotropium bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm1 cholinergic receptor, muscarinic 1 affects binding ISO Tiotropium Bromide binds to CHRM1 protein CTD PMID:21870878 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 affects binding ISO Tiotropium Bromide binds to CHRM2 protein CTD PMID:21870878 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 affects binding ISO Tiotropium Bromide binds to CHRM3 protein CTD PMID:21870878 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 affects binding ISO Tiotropium Bromide binds to CHRM4 protein CTD PMID:21870878 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 affects binding ISO Tiotropium Bromide binds to CHRM5 protein CTD PMID:21870878 NCBI chr 3:99,284,846...99,337,252
Ensembl chr 3:99,284,846...99,337,252
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO Tiotropium Bromide inhibits the reaction [Oxotremorine results in increased expression of EDN1 mRNA] CTD PMID:22796455 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Pon1 paraoxonase 1 decreases activity ISO Tiotropium Bromide results in decreased activity of PON1 protein CTD PMID:31581362 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Tnf tumor necrosis factor decreases secretion ISO Tiotropium Bromide results in decreased secretion of TNF protein CTD PMID:21352583 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
tiquizium bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO thiaton results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP thiaton inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11855677 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP thiaton inhibits the reaction [Indomethacin results in increased activity of NOS2 protein] CTD PMID:11855677 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
vecuronium bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of ABCA1 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of ABCA1 protein] CTD PMID:30036686 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of ABCG1 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of ABCG1 protein] CTD PMID:30036686 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [N-Methylscopolamine binds to CHRM1 protein] CTD PMID:9846649 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions ISO Vecuronium Bromide inhibits the reaction [N-Methylscopolamine binds to CHRM2 protein] CTD PMID:9846649 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 multiple interactions ISO Vecuronium Bromide inhibits the reaction [N-Methylscopolamine binds to CHRM3 protein] CTD PMID:9846649 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 multiple interactions ISO Vecuronium Bromide inhibits the reaction [N-Methylscopolamine binds to CHRM4 protein] CTD PMID:9846649 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 multiple interactions ISO Vecuronium Bromide inhibits the reaction [N-Methylscopolamine binds to CHRM5 protein] CTD PMID:9846649 NCBI chr 3:99,284,846...99,337,252
Ensembl chr 3:99,284,846...99,337,252
JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions ISO Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]]; Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB4 protein]] CTD PMID:16931985 NCBI chr 8:55,401,981...55,415,012
Ensembl chr 8:55,401,702...55,415,165
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]; Vecuronium Bromide inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Vecuronium Bromide results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein] CTD PMID:14645658 PMID:16931985 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions ISO Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of CHRNA7 protein] CTD PMID:16931985 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]]; Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]; Vecuronium Bromide inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Vecuronium Bromide results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein] CTD PMID:14645658 PMID:16931985 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit multiple interactions ISO Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB4 protein]] CTD PMID:16931985 NCBI chr 8:55,418,379...55,436,967
Ensembl chr 8:55,418,313...55,437,027
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of CYP11A1 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of CYP11A1 protein] CTD PMID:31846720 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of CYP19A1 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of CYP19A1 protein] CTD PMID:30959089 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in increased expression of EGR1 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in increased expression of EGR1 protein] CTD PMID:29486207 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in increased phosphorylation of ELK1 protein] CTD PMID:29486207 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713
JBrowse link
G Hdac4 histone deacetylase 4 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in increased expression of HDAC4 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in increased expression of HDAC4 protein] CTD PMID:31846720 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164
JBrowse link
G Hexb hexosaminidase subunit beta increases secretion ISO Vecuronium Bromide results in increased secretion of HEXB protein CTD PMID:19758318 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 increases expression
multiple interactions
ISO Vecuronium Bromide results in increased expression of HSD11B2 mRNA; Vecuronium Bromide results in increased expression of HSD11B2 protein
Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of HSD11B2 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of HSD11B2 protein]
CTD PMID:29486207 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in increased phosphorylation of MAPK1 protein] CTD PMID:29486207 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in increased phosphorylation of MAPK3 protein] CTD PMID:29486207 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of NR1H2 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of NR1H2 protein] CTD PMID:30036686 NCBI chr 1:95,041,967...95,047,377
Ensembl chr 1:95,041,967...95,047,377
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of NR1H3 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of NR1H3 protein] CTD PMID:30036686 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of SCARB1 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of SCARB1 protein] CTD PMID:30036686 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of STAR mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of STAR protein] CTD PMID:31846720 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20057
    chemical entity 20068
      atom 20056
        nonmetal atom 19948
          halogen 18530
            bromine atom 6626
              bromine molecular entity 6635
                bromide salt 39
                  organic bromide salt 38
                    1,1'-diethyl-2,2'-cyanine bromide 0
                    1,1'-hexadecane-1,16-diylbis(1-methylpyrrolidinium) dibromide 0
                    1-(4-amino-2-methylpyrimidin-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium bromide 0
                    1-(4-hydroxy-2-methylpyrimidin-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium bromide 0
                    3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide 5
                    DH334 0
                    DH335 0
                    FM 1-43 dye 0
                    FM 4-64 dye 0
                    X-rhod-1 0
                    aclidinium bromide 0
                    alcuronium bromide 0
                    anisotropine methylbromide 0
                    benzododecinium bromide 0
                    butropium bromide 0
                    butylscopolamine bromide 1
                    carbocyanin DBTC 0
                    cetyltrimethylammonium bromide 0
                    clidinium bromide 0
                    distigmine bromide 0
                    dodeclonium bromide 0
                    dodecyl(triphenyl)phosphonium bromide 0
                    ethidium bromide 0
                    ethyl green 0
                    flutropium bromide 0
                    glycopyrronium bromide + 0
                    homatropine methylbromide 0
                    hydrobromide + 1
                    ipratropium bromide + 0
                    propyromazine bromide 0
                    rhod-2 dye 0
                    rocuronium bromide 0
                    sepantronium bromide 0
                    tetrabutylammonium bromide 0
                    tiotropium bromide 8
                    tiquizium bromide 3
                    tridihexethyl bromide 0
                    umeclidinium bromide + 0
                    vecuronium bromide 25
Path 2
Term Annotations click to browse term
  CHEBI ontology 20057
    subatomic particle 20056
      composite particle 20068
        hadron 20056
          baryon 20056
            nucleon 20056
              atomic nucleus 20056
                atom 20056
                  main group element atom 19971
                    p-block element atom 19971
                      halogen 18530
                        halogen molecular entity 18513
                          halide 18490
                            halide salt 9366
                              bromide salt 39
                                organic bromide salt 38
                                  1,1'-diethyl-2,2'-cyanine bromide 0
                                  1,1'-hexadecane-1,16-diylbis(1-methylpyrrolidinium) dibromide 0
                                  1-(4-amino-2-methylpyrimidin-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium bromide 0
                                  1-(4-hydroxy-2-methylpyrimidin-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium bromide 0
                                  3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide 5
                                  DH334 0
                                  DH335 0
                                  FM 1-43 dye 0
                                  FM 4-64 dye 0
                                  X-rhod-1 0
                                  aclidinium bromide 0
                                  alcuronium bromide 0
                                  anisotropine methylbromide 0
                                  benzododecinium bromide 0
                                  butropium bromide 0
                                  butylscopolamine bromide 1
                                  carbocyanin DBTC 0
                                  cetyltrimethylammonium bromide 0
                                  clidinium bromide 0
                                  distigmine bromide 0
                                  dodeclonium bromide 0
                                  dodecyl(triphenyl)phosphonium bromide 0
                                  ethidium bromide 0
                                  ethyl green 0
                                  flutropium bromide 0
                                  glycopyrronium bromide + 0
                                  homatropine methylbromide 0
                                  hydrobromide + 1
                                  ipratropium bromide + 0
                                  propyromazine bromide 0
                                  rhod-2 dye 0
                                  rocuronium bromide 0
                                  sepantronium bromide 0
                                  tetrabutylammonium bromide 0
                                  tiotropium bromide 8
                                  tiquizium bromide 3
                                  tridihexethyl bromide 0
                                  umeclidinium bromide + 0
                                  vecuronium bromide 25
paths to the root