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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pyrrolopyrazine
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Accession:CHEBI:48337 term browser browse the term
Synonyms:related_synonym: pyrrolopyrazines


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zopiclone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases metabolic processing ISO CYP2C8 protein results in increased metabolism of zopiclone CTD PMID:12464242 NCBI chr 1:147,236,480...147,307,988 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    chemical entity 19785
      atom 19782
        nonmetal atom 19657
          nitrogen atom 18539
            nitrogen molecular entity 18539
              organonitrogen compound 18309
                organonitrogen heterocyclic compound 17460
                  pyrrolopyrazine 1
                    (6S,8aS)-2-(benzylsulfonyl)-N-\{[1-(N'-hydroxycarbamimidoyl)piperidin-4-yl]methyl\}-4-oxooctahydropyrrolo[1,2-a]pyrazine-6-carboxamide 0
                    (8aS)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione 0
                    (S)-3-(indol-3-ylmethyl)-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one 0
                    (S)-3-\{[2-(1,1-dimethylallyl)-indol-3-yl]methyl\}-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one 0
                    1-hydroxy-3-(indol-3-ylmethyl)-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazin-5-ylium 0
                    1-hydroxy-3-\{[2-(1,1-dimethylallyl)-indol-3-yl]methyl\}-4H,6H,7H,8H-pyrrolo[1,2-a]pyrazin-2-ium 0
                    1-hydroxy-3-\{[2-(1,1-dimethylallyl)-indol-3-yl]methyl\}-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazin-5-ylium 0
                    18-oxotryprostatin A 0
                    2-\{3-[(3S,8aS)-1,4-dioxooctahydropyrrolo[1,2-a]pyrazin-3-yl]propyl\}guanidine 0
                    4-(7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)phenol 0
                    6-hydroxydeoxybrevianamide E 0
                    6-hydroxytryprostatin B 0
                    brevianamide F + 0
                    butyl (2S,3S)-3-(trans-4-aminocyclohexyl)-3-(\{[2-(benzylsulfonyl)-4-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-6-yl]carbonyl\}amino)-2-hydroxypropanoate 0
                    cordysinin A 0
                    cyclo(L-His-L-Pro) 0
                    cyclo(L-Leu-L-Pro) 0
                    deoxybrevianamide E 0
                    maculosin 0
                    notoamide C 0
                    notoamide E 0
                    notoamide S + 0
                    tryprostatin A 0
                    tryprostatin B 0
                    zopiclone + 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      p-block molecular entity 19670
                        carbon group molecular entity 19572
                          organic molecular entity 19561
                            organic molecule 19486
                              organic cyclic compound 19282
                                organic heterocyclic compound 18407
                                  organic heteropolycyclic compound 17820
                                    organic heterobicyclic compound 16742
                                      pyrrolopyrazine 1
                                        (6S,8aS)-2-(benzylsulfonyl)-N-\{[1-(N'-hydroxycarbamimidoyl)piperidin-4-yl]methyl\}-4-oxooctahydropyrrolo[1,2-a]pyrazine-6-carboxamide 0
                                        (8aS)-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione 0
                                        (S)-3-(indol-3-ylmethyl)-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one 0
                                        (S)-3-\{[2-(1,1-dimethylallyl)-indol-3-yl]methyl\}-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one 0
                                        1-hydroxy-3-(indol-3-ylmethyl)-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazin-5-ylium 0
                                        1-hydroxy-3-\{[2-(1,1-dimethylallyl)-indol-3-yl]methyl\}-4H,6H,7H,8H-pyrrolo[1,2-a]pyrazin-2-ium 0
                                        1-hydroxy-3-\{[2-(1,1-dimethylallyl)-indol-3-yl]methyl\}-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazin-5-ylium 0
                                        18-oxotryprostatin A 0
                                        2-\{3-[(3S,8aS)-1,4-dioxooctahydropyrrolo[1,2-a]pyrazin-3-yl]propyl\}guanidine 0
                                        4-(7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)phenol 0
                                        6-hydroxydeoxybrevianamide E 0
                                        6-hydroxytryprostatin B 0
                                        brevianamide F + 0
                                        butyl (2S,3S)-3-(trans-4-aminocyclohexyl)-3-(\{[2-(benzylsulfonyl)-4-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-6-yl]carbonyl\}amino)-2-hydroxypropanoate 0
                                        cordysinin A 0
                                        cyclo(L-His-L-Pro) 0
                                        cyclo(L-Leu-L-Pro) 0
                                        deoxybrevianamide E 0
                                        maculosin 0
                                        notoamide C 0
                                        notoamide E 0
                                        notoamide S + 0
                                        tryprostatin A 0
                                        tryprostatin B 0
                                        zopiclone + 1
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