fragrance - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	fragrance	go back to main search page
Accession:	CHEBI:48318	browse the term
Definition:	A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell.
Synonyms:	related_synonym:	Parfuem; aroma; arome; essence; parfum; perfume; scent
	alt_id:	MESH:D010476
	xref_mesh:	MESH:D010476

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Rat (1449) Mouse (1472) Human (1490) Chinchilla (0) Bonobo (0) Dog (2) Squirrel (0) Pig (2) Green Monkey (0) Naked Mole-rat (0) All
Genes (1449)

fragrance

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

butyrophilin, subfamily 2, member A2

increases expression

Perfume results in increased expression of BTN2A2 mRNA

NCBI chr17:42,048,842...42,060,650
Ensembl chr17:41,620,839...41,632,618

G

cell adhesion molecule 1

decreases expression

Perfume results in decreased expression of CADM1 mRNA

NCBI chr 8:56,744,374...57,075,264
Ensembl chr 8:47,847,325...48,182,833

G

calumenin

increases expression

Perfume results in increased expression of CALU mRNA

NCBI chr 4:58,914,456...58,941,957
Ensembl chr 4:57,948,997...57,976,593

G

C-C motif chemokine ligand 12

increases expression

Perfume results in increased expression of CCL13 mRNA

NCBI chr10:67,567,876...67,569,426
Ensembl chr10:67,070,230...67,071,780

G

C-C motif chemokine ligand 17

increases expression

Perfume results in increased expression of CCL17 mRNA

NCBI chr19:10,208,120...10,218,340
Ensembl chr19:10,202,128...10,203,819

G

C-C motif chemokine ligand 19

increases expression

Perfume results in increased expression of CCL19 mRNA

NCBI chr 5:61,759,220...61,761,164
Ensembl chr 5:56,963,364...56,965,308

G

C-C motif chemokine ligand 20

increases expression

Perfume results in increased expression of CCL20 mRNA

NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:84,388,904...84,391,629

G

C-C motif chemokine ligand 21

increases expression

Perfume results in increased expression of CCL21 mRNA

NCBI chr 5:61,776,411...61,777,515
Ensembl chr 5:56,980,558...56,981,686

G

C-C motif chemokine ligand 22

increases expression

Perfume results in increased expression of CCL22 mRNA

NCBI chr19:10,263,589...10,270,359
Ensembl chr19:10,257,601...10,264,400

G

C-C motif chemokine ligand 26

increases expression

Perfume results in increased expression of CCL26 mRNA

NCBI chr12:26,745,972...26,750,924
Ensembl chr12:21,109,421...21,114,335

G

C-C motif chemokine ligand 5

increases expression

Perfume results in increased expression of CCL5 mRNA

NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377

G

C-C motif chemokine receptor 7

increases expression

Perfume results in increased expression of CCR7 mRNA

NCBI chr10:84,594,399...84,604,514
Ensembl chr10:84,097,381...84,108,309

G

Cd68 molecule

increases expression

Perfume results in increased expression of CD68 mRNA

NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,381,815...54,383,697

G

cilia and flagella associated protein 300

increases expression

Perfume results in increased expression of CFAP300 mRNA

NCBI chr 8:13,465,016...13,483,679
Ensembl chr 8:5,180,675...5,198,807

G

claudin 1

affects response to substance

CLDN1 gene SNP affects the susceptibility to Perfume

NCBI chr11:87,926,376...87,941,533
Ensembl chr11:74,421,569...74,436,724

G

C-type lectin domain family 4, member G

increases expression

Perfume results in increased expression of CLEC4G mRNA

NCBI chr12:6,578,266...6,582,913
Ensembl chr12:1,780,371...1,784,985

G

cytokine receptor-like factor 2

increases expression

Perfume results in increased expression of CRLF2 mRNA

NCBI chr14:118,932...123,632
Ensembl chr14:103,939...108,642

G

C-X-C motif chemokine ligand 10

increases expression

Perfume results in increased expression of CXCL10 mRNA

NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,704,758...15,706,975

G

C-X-C motif chemokine ligand 11

increases expression

Perfume results in increased expression of CXCL11 mRNA

NCBI chr14:15,973,728...15,976,503
Ensembl chr14:15,689,424...15,692,271

G

C-X-C motif chemokine ligand 9

increases expression

Perfume results in increased expression of CXCL9 mRNA

NCBI chr14:16,007,166...16,012,077
Ensembl chr14:15,722,908...15,728,435

G

DAB adaptor protein 2

increases expression

Perfume results in increased expression of DAB2 mRNA

NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:55,514,700...55,567,476

G

deoxyribonuclease 1L3

increases expression

Perfume results in increased expression of DNASE1L3 mRNA

NCBI chr15:19,351,683...19,378,536
Ensembl chr15:16,922,335...16,948,317

G

engulfment and cell motility 1

increases expression

Perfume results in increased expression of ELMO1 mRNA

NCBI chr17:48,982,188...49,518,525
Ensembl chr17:44,286,485...44,822,788

G

FA complementation group I

increases expression

Perfume results in increased expression of FANCI mRNA

NCBI chr 1:142,736,636...142,792,999
Ensembl chr 1:133,327,297...133,383,640

G

Fc receptor-like A

increases expression

Perfume results in increased expression of FCRLA mRNA

NCBI chr13:83,160,453...83,170,170
Ensembl chr13:83,160,398...83,170,762

G

FYVE, RhoGEF and PH domain containing 2

increases expression

Perfume results in increased expression of FGD2 mRNA

NCBI chr20:7,426,407...7,443,207
Ensembl chr20:7,424,790...7,441,603

G

forkhead box P3

increases expression

Perfume results in increased expression of FOXP3 mRNA

NCBI chr X:17,580,380...17,601,181
Ensembl chr X:14,908,494...14,923,838

G

alpha-L-fucosidase 2

increases expression

Perfume results in increased expression of FUCA2 mRNA

NCBI chr 1:7,885,986...7,900,777
Ensembl chr 1:7,885,918...7,900,776

G

GATA binding protein 3

increases expression

Perfume results in increased expression of GATA3 mRNA

NCBI chr17:73,544,234...73,575,670
Ensembl chr17:68,643,873...68,665,391

G

GLI pathogenesis-related 1

increases expression

Perfume results in increased expression of GLIPR1 mRNA

NCBI chr 7:49,373,579...49,399,190
Ensembl chr 7:47,487,345...47,498,429

G

interferon, alpha 1

decreases expression

Perfume results in decreased expression of IFNA1 mRNA

NCBI chr 5:108,143,240...108,143,809
Ensembl chr 5:103,097,356...103,097,925

G

interferon gamma

increases expression

Perfume results in increased expression of IFNG mRNA

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375

G

IKBKB interacting protein

increases expression

Perfume results in increased expression of IKBIP mRNA

NCBI chr 7:25,579,865...25,598,548
Ensembl chr 7:25,579,832...25,605,162

G

interleukin 10

increases expression

Perfume results in increased expression of IL10 mRNA

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313

G

interleukin 12B

increases expression

Perfume results in increased expression of IL12B mRNA

NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903

G

interleukin 13

increases expression

Perfume results in increased expression of IL13 mRNA

NCBI chr10:38,290,926...38,293,483
Ensembl chr10:37,790,130...37,792,737

G

interleukin 17A

increases expression

Perfume results in increased expression of IL17A mRNA

NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:23,144,402...23,147,889

G

interleukin 17F

decreases expression

Perfume results in decreased expression of IL17F mRNA

NCBI chr 9:30,686,532...30,697,918
Ensembl chr 9:23,190,100...23,201,482

G

interleukin 1 beta

increases expression

Perfume results in increased expression of IL1B mRNA

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 2

increases expression

Perfume results in increased expression of IL2 mRNA

NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 22

increases expression

Perfume results in increased expression of IL22 mRNA

NCBI chr 7:55,687,061...55,691,526
Ensembl chr 7:53,801,206...53,806,186

G

interleukin 23 subunit alpha

increases expression

Perfume results in increased expression of IL23A mRNA

NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:721,809...723,923

G

interleukin 2 receptor subunit alpha

increases expression

Perfume results in increased expression of IL2RA mRNA

NCBI chr17:71,759,802...71,808,475
Ensembl chr17:66,849,974...66,898,697

G

interleukin 31

increases expression

Perfume results in increased expression of IL31 mRNA

NCBI chr12:38,756,231...38,765,917
Ensembl chr12:33,092,097...33,105,037

G

interleukin 33

decreases expression

Perfume results in decreased expression of IL33 mRNA

NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:227,721,435...227,736,373

G

interleukin 4

increases expression

Perfume results in increased expression of IL4 mRNA

NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750

G

interleukin 5

increases expression

Perfume results in increased expression of IL5 mRNA

NCBI chr10:38,375,132...38,378,003
Ensembl chr10:37,874,342...37,877,213

G

interleukin 6

increases expression

Perfume results in increased expression of IL6 mRNA

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178

G

interleukin 7

decreases expression

Perfume results in decreased expression of IL7 mRNA

NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:94,234,766...94,280,075

G

interleukin 7 receptor

increases expression

Perfume results in increased expression of IL7R mRNA

NCBI chr 2:60,179,561...60,204,937
Ensembl chr 2:58,454,217...58,477,757

G

interleukin 9

increases expression

Perfume results in increased expression of IL9 mRNA

NCBI chr17:8,117,028...8,120,151
Ensembl chr17:8,111,772...8,114,895

G

KDEL endoplasmic reticulum protein retention receptor 3

increases expression

Perfume results in increased expression of KDELR3 mRNA

NCBI chr 7:112,959,632...112,969,858
Ensembl chr 7:111,079,218...111,101,600

G

lipocalin 2

decreases expression

Perfume results in decreased expression of LCN2 mRNA

NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:15,680,687...15,684,095

G

MAP7 domain containing 3

increases expression

Perfume results in increased expression of MAP7D3 mRNA

NCBI chr X:134,619,227...134,647,525
Ensembl chr X:134,619,227...134,685,841

G

MBL associated serine protease 1

increases expression

Perfume results in increased expression of MASP1 mRNA

NCBI chr11:90,839,081...90,909,922
Ensembl chr11:77,334,859...77,402,974

G

MX dynamin like GTPase 1

increases expression

Perfume results in increased expression of MX1 mRNA

NCBI chr11:50,269,056...50,294,699
Ensembl chr11:36,799,660...36,823,507

G

myosin VA

increases expression

Perfume results in increased expression of MYO5A mRNA

NCBI chr 8:84,692,524...84,860,564
Ensembl chr 8:75,812,412...75,975,918

G

neurotensin

increases expression

Perfume results in increased expression of NTS mRNA

NCBI chr 7:39,451,484...39,460,888
Ensembl chr 7:37,564,533...37,574,423

G

PDGFA associated protein 1

increases expression

Perfume results in increased expression of PDAP1 mRNA

NCBI chr12:14,584,414...14,594,641
Ensembl chr12:9,470,574...9,535,374

G

POC1 centriolar protein A

increases expression

Perfume results in increased expression of POC1A mRNA

NCBI chr 8:115,801,335...115,869,812
Ensembl chr 8:106,922,978...106,991,089

G

DNA polymerase epsilon 2, accessory subunit

increases expression

Perfume results in increased expression of POLE2 mRNA

NCBI chr 6:93,410,713...93,448,782
Ensembl chr 6:87,674,702...87,699,305

G

RAB32, member RAS oncogene family

increases expression

Perfume results in increased expression of RAB32 mRNA

NCBI chr 1:6,766,448...6,781,258
Ensembl chr 1:4,945,036...4,960,934

G

ribonuclease A family member 6

increases expression

Perfume results in increased expression of RNASE6 mRNA

NCBI chr15:26,827,896...26,830,807
Ensembl chr15:24,354,303...24,357,328

G

RAR-related orphan receptor C

decreases expression

Perfume results in decreased expression of RORC mRNA

NCBI chr 2:184,698,779...184,723,942
Ensembl chr 2:182,009,286...182,034,907

G

S100 calcium binding protein A8

increases expression

Perfume results in increased expression of S100A8 mRNA

NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:176,167,124...176,167,643

G

S100 calcium binding protein A9

increases expression

Perfume results in increased expression of S100A9 mRNA

NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:176,190,361...176,193,230

G

Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase

increases expression

Perfume results in increased expression of SEPSECS mRNA

NCBI chr14:58,311,484...58,341,745
Ensembl chr14:58,311,499...58,341,740

G

shugoshin 2

increases expression

Perfume results in increased expression of SGO2 mRNA

NCBI chr 9:67,032,083...67,067,439
Ensembl chr 9:59,548,683...59,573,229

G

schlafen family member 4

increases expression

Perfume results in increased expression of SLFN1 mRNA

NCBI chr10:67,994,601...68,018,141
Ensembl chr10:68,000,028...68,018,138
Ensembl chr10:68,000,028...68,018,138

G

Spi-1 proto-oncogene

increases expression

Perfume results in increased expression of SPI1 mRNA

NCBI chr 3:97,529,509...97,548,204
Ensembl chr 3:77,073,012...77,092,393

G

ssu-2 homolog

increases expression

Perfume results in increased expression of SSUH2 mRNA

NCBI chr 4:145,502,942...145,521,881
Ensembl chr 4:145,503,185...145,521,735

G

TBC1 domain family, member 31

increases expression

Perfume results in increased expression of TBC1D31 mRNA

NCBI chr 7:91,316,905...91,396,434
Ensembl chr 7:89,426,780...89,506,894

G

T-box transcription factor 21

increases expression

Perfume results in increased expression of TBX21 mRNA

NCBI chr10:82,578,751...82,595,253
Ensembl chr10:82,082,322...82,098,831

G

t-complex 11 like 1

increases expression

Perfume results in increased expression of TCP11L1 mRNA

NCBI chr 3:91,047,006...91,092,687
Ensembl chr 3:90,998,270...91,092,006

G

tudor and KH domain containing

increases expression

Perfume results in increased expression of TDRKH mRNA

NCBI chr 2:184,736,255...184,760,534
Ensembl chr 2:182,049,215...182,070,755

G

transforming growth factor, beta 1

increases expression

Perfume results in increased expression of TGFB1 mRNA

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847

G

transmembrane protein with EGF-like and two follistatin-like domains 2

increases expression

Perfume results in increased expression of TMEFF2 mRNA

NCBI chr 9:50,445,947...50,733,473
Ensembl chr 9:50,436,079...50,733,475

G

tumor necrosis factor

increases expression

Perfume results in increased expression of TNF mRNA

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629

G

TNF receptor superfamily member 4

increases expression

Perfume results in increased expression of TNFRSF4 mRNA

NCBI chr 5:171,889,134...171,891,824
Ensembl chr 5:166,606,909...166,609,599

G

TNF superfamily member 4

increases expression

Perfume results in increased expression of TNFSF4 mRNA

NCBI chr13:76,256,654...76,280,133
Ensembl chr13:73,723,329...73,746,788

G

V-set immunoregulatory receptor

increases expression

Perfume results in increased expression of VSIR mRNA

NCBI chr20:28,824,493...28,850,175
Ensembl chr20:28,281,596...28,303,878

(R)-linalyl acetate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetyl-CoA carboxylase alpha

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACACA mRNA

NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,014,170...69,276,457

G

acetyl-CoA carboxylase beta

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ACACB mRNA

NCBI chr12:48,026,394...48,138,214
Ensembl chr12:42,366,548...42,457,655

G

ATP citrate lyase

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACLY mRNA

NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,412,049...85,463,320

G

actin alpha 2, smooth muscle

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACTA2 mRNA

NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554

G

aryl hydrocarbon receptor

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of AHR mRNA

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568

G

AKT serine/threonine kinase 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of AKT1 mRNA

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921

G

androgen receptor

multiple interactions

linalyl acetate inhibits the reaction [Testosterone results in increased activity of AR protein]

NCBI chr X:67,135,317...67,304,476
Ensembl chr X:63,104,771...63,273,925

G

catalase

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of CAT mRNA

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478

G

cellular communication network factor 2

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CTGF mRNA

NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:20,802,199...20,805,734

G

collagen type I alpha 1 chain

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of COL1A1 mRNA

NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624

G

carnitine palmitoyltransferase 1A

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CPT1A mRNA

NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055

G

carnitine palmitoyltransferase 2

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CPT2 mRNA

NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:122,664,677...122,682,095

G

cathepsin D

increases expression
multiple interactions

linalyl acetate results in increased expression of CTSD mRNA
Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of CTSD mRNA]

NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:197,527,467...197,539,488

G

cytochrome P450, family 1, subfamily a, polypeptide 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CYP1A1 mRNA

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 4, subfamily f, polypeptide 6

multiple interactions

linalyl acetate inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA]

NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782

G

diacylglycerol O-acyltransferase 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of DGAT1 mRNA

NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:108,218,524...108,234,299

G

estrogen receptor 1

increases activity
multiple interactions

linalyl acetate results in increased activity of ESR1 protein
NCOA2 protein promotes the reaction [linalyl acetate results in increased activity of ESR1 protein]

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002

G

fatty acid synthase

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of FASN mRNA

NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261

G

forkhead box O1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of FOXO1 mRNA

NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:136,312,168...136,387,790

G

glutathione peroxidase 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of GPX1 mRNA

NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024

G

growth regulating estrogen receptor binding 1

increases expression
multiple interactions

linalyl acetate results in increased expression of GREB1 mRNA
Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of GREB1 mRNA]

NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633

G

glutathione-disulfide reductase

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of GSR mRNA

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661

G

intercellular adhesion molecule 1

multiple interactions

linalyl acetate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438

G

malonyl-CoA decarboxylase

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of MLYCD mRNA

NCBI chr19:64,356,582...64,372,447
Ensembl chr19:47,447,970...47,463,793

G

nuclear receptor coactivator 2

multiple interactions

NCOA2 protein promotes the reaction [linalyl acetate results in increased activity of ESR1 protein]

NCBI chr 5:10,618,712...10,852,776
Ensembl chr 5:5,835,706...6,067,451

G

NFE2 like bZIP transcription factor 2

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of NFE2L2 mRNA

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737

G

nuclear factor kappa B subunit 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of NFKB1 mRNA

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404

G

progesterone receptor

increases expression
multiple interactions

linalyl acetate results in increased expression of PGR mRNA
Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of PGR mRNA]

NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:6,072,673...6,131,344

G

peroxisome proliferator activated receptor alpha

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of PPARA mRNA

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346

G

prostaglandin-endoperoxide synthase 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of PTGS1 mRNA

NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:19,584,015...19,605,586

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

linalyl acetate inhibits the reaction [TNF protein results in increased expression of and affects the localization of RELA protein modified form]

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484

G

SEC14-like lipid binding 2

multiple interactions

linalyl acetate inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA]

NCBI chr14:83,197,384...83,222,059
Ensembl chr14:78,973,808...78,993,788

G

selectin E

multiple interactions

linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELE mRNA]

NCBI chr13:78,935,997...78,945,905
Ensembl chr13:76,403,304...76,412,741

G

selectin P

multiple interactions

linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELP mRNA]

NCBI chr13:79,009,379...79,044,994
Ensembl chr13:76,476,295...76,511,845

G

snail family transcriptional repressor 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of SNAI1 mRNA

NCBI chr 3:176,667,476...176,671,965
Ensembl chr 3:156,248,485...156,252,969

G

superoxide dismutase 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of SOD1 mRNA

NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249

G

transforming growth factor, beta 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of TGFB1 mRNA

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847

G

tumor necrosis factor

multiple interactions

linalyl acetate inhibits the reaction [TNF protein results in increased expression of and affects the localization of RELA protein modified form]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELP mRNA]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629

G

UDP glucuronosyltransferase 2 family, polypeptide B34 like 1

multiple interactions

linalyl acetate inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA]

NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704

G

vascular cell adhesion molecule 1

multiple interactions

linalyl acetate inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]

NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:204,038,114...204,057,958

G

zinc finger E-box binding homeobox 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ZEB1 mRNA

NCBI chr17:56,644,397...56,811,155
Ensembl chr17:51,948,948...52,115,214

G

zinc finger E-box binding homeobox 2

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ZEB2 mRNA

NCBI chr 3:49,624,028...49,754,323
Ensembl chr 3:29,218,301...29,345,157

(Z)-hex-3-en-1-ol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

proopiomelanocortin

multiple interactions

[2,5-dihydro-2,4,5-trimethylthiazoline co-treated with 3-hexen-1-ol co-treated with 2-hexenal] results in decreased expression of POMC protein; [3-hexen-1-ol co-treated with 2-hexenal] inhibits the reaction [2,5-dihydro-2,4,5-trimethylthiazoline results in decreased expression of POMC protein]; [3-hexen-1-ol co-treated with 2-hexenal] results in decreased expression of POMC

PMID:19103229 PMID:21515296

NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664

2-(4-hydroxyphenyl)ethanol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

glucose-6-phosphatase catalytic subunit 1

multiple interactions

4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]

NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,257,668...86,333,804

G

glucose-6-phosphate dehydrogenase

multiple interactions

4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]

NCBI chr X:157,352,364...157,372,144
Ensembl chr X:152,201,098...152,220,801

G

insulin 1

multiple interactions

4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]

NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:251,244,973...251,245,536

G

prostaglandin-endoperoxide synthase 2

multiple interactions

4-hydroxyphenylethanol inhibits the reaction [[Lipids results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188

2-aminopropiophenone

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

solute carrier family 6 member 3

decreases expression

cathinone analog results in decreased expression of SLC6A3 mRNA

NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413

acteoside

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

actin alpha 2, smooth muscle

decreases expression

acteoside results in decreased expression of ACTA2 protein

NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554

G

advanced glycosylation end product-specific receptor

decreases expression
multiple interactions

acteoside results in decreased expression of AGER mRNA; acteoside results in decreased expression of AGER protein
acteoside inhibits the reaction [HMGB1 protein results in increased expression of AGER mRNA]; acteoside inhibits the reaction [HMGB1 protein results in increased expression of AGER protein]

PMID:33522686 PMID:36112883

NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,147,890...4,151,078

G

aryl hydrocarbon receptor

multiple interactions
decreases localization

acteoside promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased localization of AHR protein]
acteoside results in decreased localization of AHR protein

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568

G

aryl hydrocarbon receptor nuclear translocator

increases localization

acteoside results in increased localization of ARNT protein

NCBI chr 2:185,686,703...185,745,546
Ensembl chr 2:182,997,736...183,056,580

G

C-C motif chemokine ligand 2

decreases expression
multiple interactions
decreases secretion

acteoside results in decreased expression of CCL2 mRNA
acteoside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 mRNA]
acteoside results in decreased secretion of CCL2 protein

PMID:21756928 PMID:21967610

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226

G

cyclin D1

decreases expression

acteoside results in decreased expression of CCND1 protein

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602

G

cyclin D2

decreases expression

acteoside results in decreased expression of CCND2 protein

NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:159,962,363...159,989,495

G

cyclin D3

decreases expression

acteoside results in decreased expression of CCND3 protein

NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:13,394,169...13,489,371

G

cyclin E1

decreases expression

acteoside results in decreased expression of CCNE1 protein

NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:90,781,949...90,791,101

G

cell division cycle 42

multiple interactions
decreases expression

acteoside inhibits the reaction [HMGB1 protein results in increased expression of and results in increased activity of CDC42 protein]; acteoside inhibits the reaction [HMGB1 protein results in increased expression of CDC42 mRNA]; acteoside results in decreased expression of and results in decreased activity of CDC42 protein
acteoside results in decreased expression of CDC42 mRNA

NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:149,553,724...149,593,111

G

cadherin 1

increases expression

acteoside results in increased expression of CDH1 protein

NCBI chr19:51,402,178...51,471,572
Ensembl chr19:34,492,371...34,561,775

G

cyclin dependent kinase 2

multiple interactions

acteoside results in decreased expression of and results in decreased activity of CDK2 protein

NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,129,811...1,137,403

G

cyclin-dependent kinase 4

decreases activity
multiple interactions

acteoside results in decreased activity of CDK4 protein
acteoside promotes the reaction [CDKN1A protein binds to CDK4 protein]; acteoside promotes the reaction [CDKN1B protein binds to CDK4 protein]

NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase 6

multiple interactions

acteoside promotes the reaction [CDKN1A protein binds to CDK6 protein]; acteoside promotes the reaction [CDKN1B protein binds to CDK6 protein]; acteoside results in decreased expression of and results in decreased activity of CDK6 protein

NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:30,646,460...30,829,634

G

cyclin-dependent kinase inhibitor 1A

increases expression
multiple interactions

acteoside results in increased expression of CDKN1A mRNA; acteoside results in increased expression of CDKN1A protein
acteoside promotes the reaction [CDKN1A protein binds to CDK4 protein]; acteoside promotes the reaction [CDKN1A protein binds to CDK6 protein]

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1B

increases expression
multiple interactions

acteoside results in increased expression of CDKN1B mRNA; acteoside results in increased expression of CDKN1B protein
acteoside promotes the reaction [CDKN1B protein binds to CDK4 protein]; acteoside promotes the reaction [CDKN1B protein binds to CDK6 protein]

NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982

G

C-X-C motif chemokine ligand 10

decreases secretion
decreases expression
multiple interactions

acteoside results in decreased secretion of CXCL10 protein
acteoside results in decreased expression of CXCL10 mRNA
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; acteoside inhibits the reaction [PD168393 results in increased secretion of CXCL10 protein]; acteoside promotes the reaction [leptomycin B results in decreased secretion of CXCL10 protein]

PMID:21756928 PMID:21967610

NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,704,758...15,706,975

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression

acteoside results in increased expression of CYP1A1 mRNA

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions

acteoside inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein]

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023

G

E2F transcription factor 1

multiple interactions

[acteoside results in decreased phosphorylation of RB1 protein] promotes the reaction [RB1 protein binds to E2F1 protein]

NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:143,049,478...143,075,361

G

epidermal growth factor receptor

decreases phosphorylation
multiple interactions

acteoside results in decreased phosphorylation of EGFR protein
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of EGFR protein]; acteoside promotes the reaction [TGFA protein affects the localization of EGFR protein modified form]; acteoside promotes the reaction [TGFA protein affects the localization of EGFR protein]

PMID:21756928 PMID:21967610

NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382

G

high mobility group box 1

decreases expression
multiple interactions

acteoside results in decreased expression of HMGB1 mRNA; acteoside results in decreased expression of HMGB1 protein
acteoside inhibits the reaction [HMGB1 protein results in increased expression of AGER mRNA]; acteoside inhibits the reaction [HMGB1 protein results in increased expression of AGER protein]; acteoside inhibits the reaction [HMGB1 protein results in increased expression of and results in increased activity of CDC42 protein]; acteoside inhibits the reaction [HMGB1 protein results in increased expression of CDC42 mRNA]

PMID:33522686 PMID:36112883

NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

G

intercellular adhesion molecule 1

decreases expression

acteoside results in decreased expression of ICAM1 mRNA

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438

G

interferon gamma

decreases expression
multiple interactions

acteoside results in decreased expression of IFNG mRNA
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of EGFR protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein]

PMID:21371465 PMID:21756928

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375

G

interleukin 6

multiple interactions
decreases expression

acteoside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]
acteoside results in decreased expression of IL6 mRNA

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178

G

integrin subunit beta 2

multiple interactions

acteoside inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of ITGB2 protein]; acteoside inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein]

NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,061,430...11,097,600

G

mitogen activated protein kinase 1

increases phosphorylation
multiple interactions
decreases phosphorylation

acteoside results in increased phosphorylation of MAPK1 protein
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]
acteoside results in decreased phosphorylation of MAPK1 protein

PMID:21756928 PMID:23527233

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

decreases phosphorylation
multiple interactions
increases phosphorylation

acteoside results in decreased phosphorylation of MAPK3 protein
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]
acteoside results in increased phosphorylation of MAPK3 protein

PMID:21756928 PMID:23527233

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863

G

NADPH oxidase 1

decreases activity

acteoside results in decreased activity of NOX1 protein

NCBI chr X:101,572,338...101,625,571
Ensembl chr X:97,279,056...97,302,236

G

prostaglandin D2 synthase

affects binding

acteoside binds to PTGDS protein

NCBI chr 3:28,680,044...28,682,978
Ensembl chr 3:8,281,899...8,284,833

G

prostaglandin-endoperoxide synthase 2

multiple interactions

[acteoside co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of PTGS2 mRNA

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188

G

Rac family small GTPase 1

decreases expression

Verbascoside decreases expression of RAC1 mRNA in colon cancer cells

RGD

NCBI chr12:16,150,411...16,170,864
Ensembl chr12:11,036,698...11,057,251

G

RB transcriptional corepressor 1

decreases phosphorylation
multiple interactions

acteoside results in decreased phosphorylation of RB1 protein
[acteoside results in decreased phosphorylation of RB1 protein] promotes the reaction [RB1 protein binds to E2F1 protein]

NCBI chr15:54,780,858...54,911,989
Ensembl chr15:48,371,296...48,502,302

G

RELA proto-oncogene, NF-kB subunit

increases phosphorylation
multiple interactions
decreases phosphorylation

acteoside results in increased phosphorylation of RELA protein
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; acteoside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of RELA protein]
acteoside results in decreased phosphorylation of RELA protein

PMID:21756928 PMID:23527233

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484

G

SMAD family member 2

increases phosphorylation

acteoside results in increased phosphorylation of SMAD2 protein

NCBI chr18:72,124,792...72,193,345
Ensembl chr18:69,850,377...69,912,323

G

SMAD family member 3

increases phosphorylation

acteoside results in increased phosphorylation of SMAD3 protein

NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:64,110,039...64,236,960

G

SMAD family member 7

increases expression

acteoside results in increased expression of SMAD7 protein

NCBI chr18:71,263,508...71,291,849
Ensembl chr18:68,988,429...69,016,765

G

snail family transcriptional repressor 1

decreases expression

acteoside results in decreased expression of SNAI1 protein

NCBI chr 3:176,667,476...176,671,965
Ensembl chr 3:156,248,485...156,252,969

G

snail family transcriptional repressor 2

decreases expression

acteoside results in decreased expression of SNAI2 protein

NCBI chr11:99,686,934...99,690,349
Ensembl chr11:86,181,909...86,186,200

G

superoxide dismutase 2

decreases expression

acteoside results in decreased expression of SOD2 mRNA

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189

G

transforming growth factor alpha

multiple interactions

[acteoside co-treated with TGFA protein] results in increased expression of CXCL8 mRNA; acteoside promotes the reaction [TGFA protein affects the localization of EGFR protein modified form]; acteoside promotes the reaction [TGFA protein affects the localization of EGFR protein]

PMID:21756928 PMID:21967610

NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:118,618,269...118,700,894

G

transforming growth factor, beta 1

increases expression

acteoside results in increased expression of TGFB1 mRNA

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847

G

transforming growth factor, beta receptor 1

decreases expression

acteoside results in decreased expression of TGFBR1 protein

NCBI chr 5:66,449,348...66,506,371
Ensembl chr 5:61,653,233...61,710,777

G

transforming growth factor, beta receptor 2

decreases expression

acteoside results in decreased expression of TGFBR2 protein

NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:115,794,537...115,883,228

G

tumor necrosis factor

multiple interactions

acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of EGFR protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein]

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629

G

vascular cell adhesion molecule 1

decreases expression

acteoside results in decreased expression of VCAM1 mRNA

NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:204,038,114...204,057,958

benzaldehyde

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aldehyde dehydrogenase 1 family, member A1

increases oxidation
increases metabolic processing

ALDH1A1 protein results in increased oxidation of benzaldehyde
ALDH1A1 protein results in increased metabolism of benzaldehyde

PMID:10998257 PMID:21256123

NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 2 family member

increases metabolic processing
multiple interactions

ALDH2 protein results in increased metabolism of benzaldehyde
benzaldehyde inhibits the reaction [4-dimethylaminocinnamaldehyde binds to ALDH2 protein]

PMID:10609638 PMID:11744614

NCBI chr12:40,610,244...40,643,220
Ensembl chr12:34,901,219...34,982,521

G

aldehyde dehydrogenase 3 family, member A1

multiple interactions
increases oxidation
increases metabolic processing

[ALDH3A1 protein co-treated with NAD] results in increased oxidation of benzaldehyde; [ALDH3A1 protein co-treated with NADP] results in increased oxidation of benzaldehyde; Cimetidine inhibits the reaction [ALDH3A1 protein results in increased oxidation of benzaldehyde]
ALDH3A1 protein results in increased metabolism of benzaldehyde

PMID:10856427 PMID:21256123 PMID:21349255 PMID:23220590 PMID:25512087

NCBI chr10:46,392,464...46,402,151
Ensembl chr10:45,892,924...45,902,681

G

aldehyde dehydrogenase 3 family, member B1

affects binding

benzaldehyde binds to ALDH3B1 protein

NCBI chr 1:210,574,545...210,605,188
Ensembl chr 1:201,145,309...201,163,921

G

androgen receptor

multiple interactions

benzaldehyde inhibits the reaction [Metribolone binds to AR protein]

NCBI chr X:67,135,317...67,304,476
Ensembl chr X:63,104,771...63,273,925

G

olfactory receptor family 8 subfamily A member 1B

multiple interactions

benzaldehyde binds to and results in increased activity of OR8A1 protein

NCBI chr 8:45,623,650...45,624,579
Ensembl chr 8:37,434,551...37,439,746

G

solute carrier family 2 member 1

increases activity
multiple interactions

benzaldehyde results in increased activity of SLC2A1 protein
[benzaldehyde co-treated with Glucose deficiency] results in decreased activity of SLC2A1 protein

NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:132,717,196...132,745,416

benzyl acetate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ectonucleotide pyrophosphatase/phosphodiesterase 2

increases expression

benzyl acetate results in increased expression of ENPP2 mRNA; benzyl acetate results in increased expression of ENPP2 protein

NCBI chr 7:88,092,140...88,214,758
Ensembl chr 7:86,202,350...86,324,827

G

matrix metallopeptidase 9

increases expression

benzyl acetate results in increased expression of MMP9 mRNA; benzyl acetate results in increased expression of MMP9 protein

NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120

G

protein phosphatase 3 catalytic subunit alpha

multiple interactions

benzyl acetate results in increased cleavage of and results in increased activity of PPP3CA protein

NCBI chr 2:227,839,058...228,113,560
Ensembl chr 2:225,165,766...225,438,974

benzyl alcohol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aldo-keto reductase family 1 member B1

increases oxidation

AKR1B1 protein results in increased oxidation of Benzyl Alcohol

NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:62,932,031...62,946,157

G

interleukin 1 alpha

increases expression

Benzyl Alcohol results in increased expression of IL1A protein

NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822

G

LIF, interleukin 6 family cytokine

increases expression

Benzyl Alcohol results in increased expression of LIF protein

NCBI chr14:83,354,602...83,364,053
Ensembl chr14:79,134,574...79,140,482

G

sulfotransferase family 1A member 1

increases sulfation

SULT1A1 protein results in increased sulfation of Benzyl Alcohol

NCBI chr 1:190,702,592...190,706,112
Ensembl chr 1:181,272,023...181,275,562

G

sulfotransferase family 1B member 1

increases sulfation

SULT1B1 protein results in increased sulfation of Benzyl Alcohol

NCBI chr14:20,771,917...20,784,665
Ensembl chr14:20,492,708...20,505,483

G

UDP glucuronosyltransferase 2 family, polypeptide B1

increases glucuronidation

UGT2B1 protein results in increased glucuronidation of Benzyl Alcohol

NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,024,006...21,035,986

benzyl benzoate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

activating transcription factor 3

increases expression

benzyl benzoate results in increased expression of ATF3 mRNA

NCBI chr13:105,274,103...105,331,653
Ensembl chr13:102,751,321...102,764,631

G

CD86 molecule

increases expression

benzyl benzoate results in increased expression of CD86 protein

NCBI chr11:77,647,565...77,706,178
Ensembl chr11:64,163,828...64,200,818

G

estrogen receptor 1

multiple interactions

benzyl benzoate inhibits the reaction [Estradiol binds to ESR1 protein]

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

multiple interactions

benzyl benzoate inhibits the reaction [Estradiol binds to ESR2 protein]

NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919

G

monoamine oxidase A

decreases activity

benzyl benzoate results in decreased activity of MAOA protein

NCBI chr X:8,615,239...8,681,372
Ensembl chr X:6,030,795...6,099,593

G

monoamine oxidase B

decreases activity

benzyl benzoate results in decreased activity of MAOB protein

NCBI chr X:8,490,405...8,594,065
Ensembl chr X:5,907,266...6,011,003

G

neurofilament heavy chain

affects expression

benzyl benzoate affects the expression of NEFH mRNA

NCBI chr14:84,044,428...84,054,413
Ensembl chr14:79,830,362...79,840,351

G

trefoil factor 1

increases expression

benzyl benzoate results in increased expression of TFF1 mRNA

NCBI chr20:9,237,095...9,240,956
Ensembl chr20:9,235,736...9,239,597

benzyl cinnamate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aldo-keto reductase family 1, member C2

increases expression

benzyl cinnamate results in increased expression of AKR1C2 mRNA

NCBI chr17:70,669,684...70,717,935
Ensembl chr17:65,759,788...65,775,764

G

CD86 molecule

increases expression

benzyl cinnamate results in increased expression of CD86 protein

NCBI chr11:77,647,565...77,706,178
Ensembl chr11:64,163,828...64,200,818

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression

benzyl cinnamate results in increased expression of CYP1A1 mRNA

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125

G

MAF bZIP transcription factor F

increases expression

benzyl cinnamate results in increased expression of MAFF mRNA

NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:110,912,499...110,923,851

G

monoamine oxidase A

decreases activity

benzyl cinnamate results in decreased activity of MAOA protein

NCBI chr X:8,615,239...8,681,372
Ensembl chr X:6,030,795...6,099,593

G

monoamine oxidase B

decreases activity

benzyl cinnamate results in decreased activity of MAOB protein

NCBI chr X:8,490,405...8,594,065
Ensembl chr X:5,907,266...6,011,003

G

metallothionein 1

increases expression

benzyl cinnamate results in increased expression of MT1A mRNA

NCBI chr19:10,831,959...10,832,975
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr X:10,826,032...10,827,049

G

metallothionein 2

increases expression

benzyl cinnamate results in increased expression of MT2A mRNA

NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,832,002...10,832,784

G

NAD(P)H quinone dehydrogenase 1

increases expression

benzyl cinnamate results in increased expression of NQO1 mRNA

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557

G

thioredoxin 1

increases expression

benzyl cinnamate results in increased expression of TXN mRNA

NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:72,711,933...72,724,629

Benzyl parahydroxybenzoate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adiponectin, C1Q and collagen domain containing

increases expression

benzylparaben results in increased expression of ADIPOQ mRNA

NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564

G

alpha-fetoprotein

affects binding

benzylparaben binds to AFP protein

PMID:23013281 PMID:25349334

NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,573,412...17,591,480

G

CCAAT/enhancer binding protein alpha

increases expression

benzylparaben results in increased expression of CEBPA mRNA

PMID:22956630 PMID:27659731

NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:87,759,433...87,762,412

G

estrogen receptor 1

multiple interactions

benzylparaben binds to and results in increased activity of ESR1 protein

PMID:23220609 PMID:23567241

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

multiple interactions

benzylparaben binds to and results in increased activity of ESR2 protein

NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919

G

estrogen-related receptor gamma

multiple interactions

benzylparaben inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]]

NCBI chr13:101,699,043...102,316,877
Ensembl chr13:99,564,669...99,783,397

G

fatty acid amide hydrolase

decreases activity

benzylparaben results in decreased activity of FAAH protein

NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:129,479,824...129,498,677

G

fatty acid binding protein 4

increases expression

benzylparaben results in increased expression of FABP4 mRNA

PMID:22956630 PMID:27659731

NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:91,580,885...91,585,578

G

fatty acid synthase

increases expression

benzylparaben results in increased expression of FASN mRNA

NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261

G

leptin

decreases expression
increases expression

benzylparaben results in decreased expression of LEP mRNA
benzylparaben results in increased expression of LEP mRNA

NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262

G

nuclear receptor coactivator 2

multiple interactions

benzylparaben inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]]

NCBI chr 5:10,618,712...10,852,776
Ensembl chr 5:5,835,706...6,067,451

G

nuclear receptor subfamily 1, group I, member 2

increases expression

benzylparaben results in increased expression of NR1I2 mRNA

NCBI chr11:75,965,717...76,006,733
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor subfamily 1, group I, member 3

increases activity

benzylparaben results in increased activity of NR1I3 protein

NCBI chr13:86,165,327...86,170,362
Ensembl chr13:83,632,899...83,637,906

G

peroxisome proliferator activated receptor alpha

increases expression

benzylparaben results in increased expression of PPARA mRNA

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346

G

peroxisome proliferator-activated receptor gamma

increases expression
increases activity

benzylparaben results in increased expression of PPARG mRNA
benzylparaben results in increased activity of PPARG protein

PMID:22956630 PMID:27659731 PMID:28527915

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468

G

sex hormone binding globulin

affects binding

benzylparaben binds to SHBG protein

NCBI chr10:54,831,716...54,849,162
Ensembl chr10:54,332,941...54,351,057

beta-damascenone

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

calmodulin-like 5

increases expression

beta-damascenone results in increased expression of CALM4 mRNA

NCBI chr17:71,304,326...71,305,245

G

caspase 14

increases expression
affects localization

beta-damascenone results in increased expression of CASP14 mRNA
beta-damascenone affects the localization of CASP14 protein

NCBI chr 7:11,577,315...11,583,987
Ensembl chr 7:10,926,725...10,933,405

G

carboxylesterase 3a

increases expression

beta-damascenone results in increased expression of CES3 mRNA

NCBI chr19:49,902,312...49,910,484

G

chloride channel accessory 1

increases expression

beta-damascenone results in increased expression of CLCA1 mRNA

NCBI chr 2:236,599,022...236,624,714
Ensembl chr 2:233,938,677...233,964,369

G

chloride channel accessory 2

increases expression

beta-damascenone results in increased expression of CLCA2 mRNA

NCBI chr 2:236,655,419...236,682,669
Ensembl chr 2:233,995,078...234,022,199

G

cytochrome P450, family 17, subfamily a, polypeptide 1

increases expression

beta-damascenone results in increased expression of CYP17A1 mRNA

NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:245,535,462...245,541,573

G

Fc gamma binding protein

increases expression

beta-damascenone results in increased expression of FCGBP mRNA

NCBI chr 1:83,374,979...83,413,082
Ensembl chr 1:83,372,127...83,413,083

G

filaggrin

increases expression

beta-damascenone results in increased expression of FLG mRNA; beta-damascenone results in increased expression of FLG protein

NCBI chr 2:178,884,793...178,912,986

G

hornerin

increases expression

beta-damascenone results in increased expression of HRNR mRNA

NCBI chr 2:181,650,772...181,663,633

G

interleukin 20 receptor subunit alpha

increases expression

beta-damascenone results in increased expression of IL20RA mRNA

NCBI chr 1:16,243,683...16,313,229
Ensembl chr 1:14,451,228...14,493,602

G

interleukin 36 receptor antagonist

increases expression

beta-damascenone results in increased expression of IL36RN mRNA

NCBI chr 3:27,442,679...27,449,306
Ensembl chr 3:7,044,406...7,051,016

G

keratin 1

increases expression

beta-damascenone results in increased expression of KRT1 mRNA

NCBI chr 7:134,855,311...134,860,537
Ensembl chr 7:132,976,620...132,981,844

G

keratin 10

increases expression

beta-damascenone results in increased expression of KRT10 mRNA

NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701

G

late cornified envelope 1B

increases expression

beta-damascenone results in increased expression of LCE1B mRNA

NCBI chr 2:178,255,351...178,257,533
Ensembl chr 2:178,256,213...178,257,985

G

late cornified envelope 1F

increases expression

beta-damascenone results in increased expression of LCE1F mRNA

NCBI chr 2:178,305,786...178,307,372
Ensembl chr 2:178,305,786...178,307,372

G

lipase, family member M

increases expression

beta-damascenone results in increased expression of LIPM mRNA

NCBI chr 1:241,031,382...241,050,796
Ensembl chr 1:231,618,284...231,637,410

G

loricrin cornified envelope precursor protein

increases expression

beta-damascenone results in increased expression of LORICRIN mRNA

NCBI chr 2:180,253,674...180,256,572
Ensembl chr 2:177,558,252...177,559,807

G

otopetrin 3

increases expression

beta-damascenone results in increased expression of OTOP3 mRNA

NCBI chr10:100,577,346...100,588,729
Ensembl chr10:100,577,392...100,588,726

G

phospholipase A2, group IVF

increases expression

beta-damascenone results in increased expression of PLA2G4F mRNA

NCBI chr 3:127,702,603...127,720,429
Ensembl chr 3:107,250,075...107,264,689

G

phosphatidylinositol-specific phospholipase C, X domain containing 1

increases expression

beta-damascenone results in increased expression of PLCXD1 mRNA

NCBI chr12:46,578,917...46,582,181
Ensembl chr12:46,579,225...46,582,392

G

short chain dehydrogenase/reductase family 16C, member 5

increases expression

beta-damascenone results in increased expression of SDR16C5 mRNA

NCBI chr 5:21,816,394...21,841,596
Ensembl chr 5:17,018,813...17,040,970

G

sushi domain containing 2

increases expression

beta-damascenone results in increased expression of SUSD2 mRNA

NCBI chr20:13,016,960...13,024,264
Ensembl chr20:13,017,477...13,024,903

G

transmembrane serine protease 4

increases expression

beta-damascenone results in increased expression of TMPRSS4 mRNA

NCBI chr 8:54,372,805...54,405,157
Ensembl chr 8:45,476,053...45,508,409

beta-ionone

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BCL2 associated X, apoptosis regulator

increases expression

beta-ionone results in increased expression of BAX protein

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368

G

BCL2, apoptosis regulator

decreases expression
multiple interactions

beta-ionone results in decreased expression of BCL2 protein
3-methyladenine inhibits the reaction [beta-ionone results in decreased expression of BCL2 protein]; dorsomorphin inhibits the reaction [beta-ionone results in decreased expression of BCL2 protein]; Hydroxychloroquine inhibits the reaction [beta-ionone results in decreased expression of BCL2 protein]; STK11 protein affects the reaction [beta-ionone results in decreased expression of BCL2 protein]

PMID:23100158 PMID:31506784 PMID:36843289

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

caspase 3

multiple interactions
increases cleavage
increases expression

[alpha-Tocopherol co-treated with beta-ionone] results in increased activity of CASP3 protein
beta-ionone results in increased cleavage of CASP3 protein
beta-ionone results in increased expression of CASP3 protein modified form

PMID:17618090 PMID:23100158 PMID:31506784

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648

G

caspase 9

increases cleavage

beta-ionone results in increased cleavage of CASP9 protein

Ensembl chr 5:154,109,046...154,126,626

G

cyclin D1

decreases expression

beta-ionone results in decreased expression of CCND1 protein

PMID:15450939 PMID:31506784

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602

G

cyclin dependent kinase 2

decreases expression

beta-ionone results in decreased expression of CDK2 protein

NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,129,811...1,137,403

G

cyclin-dependent kinase 4

decreases expression

beta-ionone results in decreased expression of CDK4 protein

PMID:15450939 PMID:31506784

NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:62,883,105...62,942,403

G

crystallin zeta

increases activity

beta-ionone results in increased activity of CRYZ protein

NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758

G

3-hydroxy-3-methylglutaryl-CoA reductase

multiple interactions

beta-ionone promotes the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of HMGCR mRNA]

NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703

G

lamin B1

decreases farnesylation

beta-ionone results in decreased farnesylation of LMNB1 protein

NCBI chr18:52,373,939...52,413,284
Ensembl chr18:50,175,874...50,214,502

G

microtubule-associated protein 1 light chain 3 beta

multiple interactions

3-methyladenine inhibits the reaction [beta-ionone results in increased expression of and results in increased lipidation of MAP1LC3B protein]; beta-ionone results in increased expression of and results in increased lipidation of MAP1LC3B protein; STK11 protein affects the reaction [beta-ionone results in increased lipidation of MAP1LC3B protein]

NCBI chr19:66,571,631...66,582,270
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690

G

mitogen activated protein kinase 1

increases phosphorylation
multiple interactions

beta-ionone results in increased phosphorylation of MAPK1 protein
beta-ionone inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK1 protein modified form]

PMID:23268108 PMID:27226631

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

multiple interactions
increases phosphorylation

beta-ionone inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK3 protein modified form]
beta-ionone results in increased phosphorylation of MAPK3 protein

PMID:23268108 PMID:27226631

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863

G

nuclear factor kappa B subunit 1

multiple interactions

beta-ionone inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein]

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404

G

nitric oxide synthase 2

multiple interactions

beta-ionone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; beta-ionone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210

G

olfactory receptor 59

multiple interactions

beta-ionone binds to and results in increased activity of OR51E2 protein

NCBI chr 1:166,604,972...166,639,634
Ensembl chr 1:157,193,080...157,211,179

G

poly (ADP-ribose) polymerase 1

multiple interactions
increases cleavage

3-methyladenine inhibits the reaction [beta-ionone results in increased cleavage of PARP1 protein]; dorsomorphin inhibits the reaction [beta-ionone results in increased cleavage of PARP1 protein]; Hydroxychloroquine inhibits the reaction [beta-ionone results in increased cleavage of PARP1 protein]; STK11 protein affects the reaction [beta-ionone results in increased cleavage of PARP1 protein]

NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404

G

prostaglandin-endoperoxide synthase 2

multiple interactions

beta-ionone inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; beta-ionone inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
beta-ionone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]

PMID:23268108 PMID:31506784

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

beta-ionone inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484

G

serine/threonine kinase 11

increases phosphorylation
multiple interactions

beta-ionone results in increased phosphorylation of STK11 protein
STK11 protein affects the reaction [beta-ionone results in decreased expression of BCL2 protein]; STK11 protein affects the reaction [beta-ionone results in increased cleavage of PARP1 protein]; STK11 protein affects the reaction [beta-ionone results in increased lipidation of MAP1LC3B protein]

NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:9,575,269...9,591,315

G

tumor necrosis factor

multiple interactions

beta-ionone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; beta-ionone inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629

G

tyrosinase

increases expression

beta-ionone results in increased expression of TYR mRNA; beta-ionone results in increased expression of TYR protein

NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:141,115,036...141,210,207

beta-myrcene

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cytochrome P450, family 1, subfamily a, polypeptide 1

decreases activity

beta-myrcene results in decreased activity of CYP1A1 protein

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 2, subfamily b, polypeptide 1

decreases activity

beta-myrcene results in decreased activity of CYP2B1 protein

NCBI chr 1:90,646,098...90,669,762
Ensembl chr 1:81,518,408...81,542,052

Butylbenzyl phthalate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha 1,4-galactosyltransferase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of A4GALT mRNA

NCBI chr 7:114,368,525...114,392,872
Ensembl chr 7:114,368,276...114,396,071

G

ATP binding cassette subfamily A member 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ABCA1 mRNA

NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:67,681,297...67,801,170

G

ATP binding cassette subfamily B member 1A

increases expression

butylbenzyl phthalate results in increased expression of ABCB1 protein

NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily C member 2

increases expression
multiple interactions

butylbenzyl phthalate results in increased expression of ABCC2 mRNA
[dimethyl phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate] results in increased expression of ABCC2 mRNA

NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily C member 3

increases expression
multiple interactions

butylbenzyl phthalate results in increased expression of ABCC3 mRNA
[dimethyl phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate] results in increased expression of ABCC3 mRNA

PMID:26519955 PMID:35739735

NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily C member 4

multiple interactions
increases expression

[dimethyl phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate] results in increased expression of ABCC4 mRNA
butylbenzyl phthalate results in increased expression of ABCC4 mRNA

NCBI chr15:101,948,387...102,182,912
Ensembl chr15:95,542,315...95,774,283

G

ATP binding cassette subfamily G member 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ABCG1 mRNA

NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,126,687...9,182,948

G

ATP binding cassette subfamily G member 2

multiple interactions
increases expression

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ABCG2 mRNA
[dimethyl phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate] results in increased expression of ABCG2 mRNA
butylbenzyl phthalate results in increased expression of ABCG2 mRNA

PMID:31199487 PMID:35739735

NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:87,745,319...87,802,409

G

ATP binding cassette subfamily G member 5

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ABCG5 mRNA

NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:9,965,118...9,990,563

G

acetyl-CoA acyltransferase 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ACAA2 mRNA

NCBI chr18:70,620,310...70,648,417
Ensembl chr18:68,345,012...68,373,249

G

acetyl-CoA carboxylase alpha

multiple interactions

[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of ACACA protein; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ACACA mRNA; [butylbenzyl phthalate co-treated with Dietary Fats] results in increased expression of ACACA mRNA

PMID:26820058 PMID:32905190 PMID:35739755

NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,014,170...69,276,457

G

ATP citrate lyase

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ACLY mRNA

NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,412,049...85,463,320

G

acyl-CoA thioesterase 1

increases expression

butylbenzyl phthalate results in increased expression of ACOT1 mRNA

NCBI chr 6:109,367,274...109,375,268
Ensembl chr 6:103,636,041...103,644,163

G

acyl-CoA thioesterase 2

multiple interactions

[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ACOT2 protein

NCBI chr 6:109,341,426...109,352,818
Ensembl chr 6:103,611,544...103,619,245

G

acyl-CoA oxidase 1

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in decreased expression of ACOX1 mRNA

NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,406,197...101,431,232

G

acyl-CoA synthetase bubblegum family member 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ACSBG1 mRNA

NCBI chr 8:63,887,433...63,943,486
Ensembl chr 8:54,991,296...55,047,391

G

acyl-CoA synthetase family member 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ACSF2 mRNA

NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673

G

acyl-CoA synthetase short-chain family member 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ACSS1 mRNA

NCBI chr 3:159,910,809...159,960,748
Ensembl chr 3:139,450,383...139,500,325

G

actin alpha 2, smooth muscle

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ACTA2 mRNA; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ACTA2 protein

NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554

G

ADAM metallopeptidase with thrombospondin type 1 motif, 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of ADAMTS1 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of ADAMTS1 mRNA]
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein affects the expression of ADAMTS1 mRNA]

PMID:33316053 PMID:37552060

NCBI chr11:38,418,565...38,427,384
Ensembl chr11:24,931,761...24,941,103

G

ADAM metallopeptidase with thrombospondin type 1 motif, 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ADAMTS2 mRNA

NCBI chr10:35,422,030...35,627,483
Ensembl chr10:34,921,049...35,123,821

G

adhesion G protein-coupled receptor L1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ADGRL1 mRNA

NCBI chr19:41,107,162...41,148,752
Ensembl chr19:24,204,360...24,244,139

G

adiponectin, C1Q and collagen domain containing

multiple interactions

[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of ADIPOQ mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of ADIPOQ protein; [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of ADIPOQ mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased secretion of ADIPOQ protein; butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA]]
butylbenzyl phthalate promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]; butylbenzyl phthalate promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]; butylbenzyl phthalate promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]

PMID:26820058 PMID:28595985 PMID:31016361 PMID:32407875 PMID:34864131 More...

NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564

G

adrenoceptor beta 3

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased expression of ADRB3 mRNA

NCBI chr16:71,544,603...71,547,410
Ensembl chr16:64,841,788...64,844,552

G

aryl hydrocarbon receptor

affects localization
affects activity
increases expression
multiple interactions

butylbenzyl phthalate affects the localization of AHR protein
butylbenzyl phthalate affects the activity of AHR protein
butylbenzyl phthalate results in increased expression of AHR mRNA; butylbenzyl phthalate results in increased expression of AHR protein
3',4'-dimethoxyflavone inhibits the reaction [butylbenzyl phthalate results in increased expression of AHR mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [butylbenzyl phthalate results in increased expression of AHR protein]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of ARNT mRNA]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of ARNT protein]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 mRNA]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 protein]; butylbenzyl phthalate binds to and results in increased activity of AHR protein; butylbenzyl phthalate promotes the reaction [AHR protein binds to ARNT protein]; butylbenzyl phthalate promotes the reaction [AHR protein binds to CYP1B1 promoter]

PMID:18294747 PMID:22138065 PMID:23220035

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568

G

alpha-2-HS-glycoprotein

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in decreased expression of AHSG mRNA

NCBI chr11:91,625,975...91,632,583
Ensembl chr11:78,117,918...78,145,999

G

adenylate kinase 5

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of AK5 mRNA

NCBI chr 2:244,057,240...244,241,372
Ensembl chr 2:241,397,297...241,581,458

G

A-kinase anchoring protein 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of AKAP1 mRNA

NCBI chr10:74,118,232...74,151,366
Ensembl chr10:73,621,883...73,653,896

G

AKT serine/threonine kinase 1

increases phosphorylation
multiple interactions
decreases phosphorylation
affects phosphorylation

butylbenzyl phthalate results in increased phosphorylation of AKT1 protein
[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased phosphorylation of AKT1 protein
butylbenzyl phthalate results in decreased phosphorylation of AKT1 protein
butylbenzyl phthalate affects the phosphorylation of AKT1 protein
HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of AKT1 protein]

PMID:22552774 PMID:29864457 PMID:31319113 PMID:33395283 PMID:35739755

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921

G

AKT serine/threonine kinase 2

increases phosphorylation
multiple interactions

butylbenzyl phthalate results in increased phosphorylation of AKT2 protein
[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased phosphorylation of AKT2 protein

PMID:31319113 PMID:35739755

NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:82,883,547...82,933,817

G

AKT serine/threonine kinase 3

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased phosphorylation of AKT3 protein

NCBI chr13:91,475,839...91,758,060
Ensembl chr13:88,946,091...89,225,708

G

aldehyde dehydrogenase 1 family, member A1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of ALDH1A1 mRNA

NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 1 family, member A2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ALDH1A2 mRNA

NCBI chr 8:80,758,641...80,837,891
Ensembl chr 8:71,877,850...71,957,107

G

aldolase, fructose-bisphosphate C

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ALDOC mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of ALDOC protein

PMID:31199487 PMID:37690569

NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,217,451...63,221,066

G

arachidonate 15-lipoxygenase

decreases expression

butylbenzyl phthalate results in decreased expression of ALOX15 mRNA

NCBI chr10:55,559,060...55,567,535
Ensembl chr10:55,060,412...55,068,874

G

alkaline phosphatase, biomineralization associated

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ALPL protein

NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:149,951,409...150,006,446

G

anti-Mullerian hormone

multiple interactions
increases expression

[butylbenzyl phthalate co-treated with 4-vinyl-1-cyclohexene dioxide] results in decreased expression of AMH mRNA; [butylbenzyl phthalate co-treated with Dibutyl Phthalate] results in decreased expression of AMH mRNA; butylbenzyl phthalate promotes the reaction [4-vinyl-1-cyclohexene dioxide results in decreased expression of AMH protein]
butylbenzyl phthalate results in increased expression of AMH mRNA; butylbenzyl phthalate results in increased expression of AMH protein

PMID:29969652 PMID:31319113

NCBI chr 7:9,557,451...9,559,867
Ensembl chr 7:8,906,836...8,909,282

G

adenosine monophosphate deaminase 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of AMPD3 mRNA

NCBI chr 1:174,319,526...174,364,605
Ensembl chr 1:164,885,320...164,929,887

G

angiopoietin 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased secretion of ANGPT2 protein

NCBI chr16:77,790,760...77,841,241
Ensembl chr16:71,088,364...71,138,804

G

angiopoietin-like 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased secretion of ANGPTL3 protein

NCBI chr 5:118,818,494...118,825,531
Ensembl chr 5:113,703,012...113,709,957

G

angiopoietin-like 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of ANGPTL4 mRNA

NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:14,550,311...14,556,519

G

ankyrin repeat domain containing 50

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ANKRD50 mRNA

NCBI chr 2:121,466,275...121,500,758
Ensembl chr 2:121,468,573...121,500,752

G

alanyl aminopeptidase, membrane

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ANPEP mRNA

NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789

G

ANTXR cell adhesion molecule 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ANTXR1 mRNA

NCBI chr 4:121,148,102...121,335,549
Ensembl chr 4:119,590,771...119,778,232

G

apoptotic peptidase activating factor 1

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of APAF1 mRNA

NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:25,494,609...25,579,540

G

APC regulator of WNT signaling pathway 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of APC2 mRNA

NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310

G

amyloid beta precursor like protein 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of APLP1 mRNA

NCBI chr 1:94,824,330...94,834,705
Ensembl chr 1:85,696,882...85,707,155

G

amyloid beta precursor like protein 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of APLP2 mRNA

NCBI chr 8:37,857,407...37,920,487
Ensembl chr 8:29,599,230...29,661,855

G

apolipoprotein E

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of APOE mRNA

NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932

G

aquaporin 1

decreases expression

butylbenzyl phthalate results in decreased expression of AQP1 mRNA

NCBI chr 4:85,812,784...85,824,964
Ensembl chr 4:84,482,512...84,494,690

G

aquaporin 7

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of AQP7 mRNA

NCBI chr 5:60,968,495...60,982,618
Ensembl chr 5:56,172,519...56,186,642

G

androgen receptor

multiple interactions
affects binding
affects activity
decreases activity

butylbenzyl phthalate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; butylbenzyl phthalate inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; butylbenzyl phthalate inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; butylbenzyl phthalate inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]
butylbenzyl phthalate binds to AR protein
butylbenzyl phthalate affects the activity of AR protein
butylbenzyl phthalate results in decreased activity of AR protein

PMID:9846162 PMID:14565775 PMID:15840436 PMID:18294747 PMID:20943248 More...

NCBI chr X:67,135,317...67,304,476
Ensembl chr X:63,104,771...63,273,925

G

Rho GTPase activating protein 18

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ARHGAP18 mRNA

NCBI chr 1:18,403,531...18,637,306
Ensembl chr 1:18,403,537...18,637,256

G

Rho GTPase activating protein 6

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ARHGAP6 mRNA

NCBI chr X:24,953,464...25,490,003
Ensembl chr X:24,953,464...25,488,663

G

Rho/Rac guanine nucleotide exchange factor 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ARHGEF2 mRNA

NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:174,062,976...174,118,355

G

aryl hydrocarbon receptor nuclear translocator

multiple interactions
increases expression

3',4'-dimethoxyflavone inhibits the reaction [butylbenzyl phthalate results in increased expression of ARNT mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [butylbenzyl phthalate results in increased expression of ARNT protein]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of ARNT mRNA]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of ARNT protein]; butylbenzyl phthalate promotes the reaction [AHR protein binds to ARNT protein]
butylbenzyl phthalate results in increased expression of ARNT mRNA; butylbenzyl phthalate results in increased expression of ARNT protein

NCBI chr 2:185,686,703...185,745,546
Ensembl chr 2:182,997,736...183,056,580

G

aryl hydrocarbon receptor nuclear translocator 2

multiple interactions
decreases expression

1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [butylbenzyl phthalate results in decreased expression of ARNT2 mRNA]
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ARNT2 mRNA

PMID:21771643 PMID:31199487

NCBI chr 1:147,645,354...147,801,986
Ensembl chr 1:138,189,940...138,393,153

G

arrestin domain containing 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ARRDC3 mRNA

NCBI chr 2:12,873,202...12,885,716
Ensembl chr 2:11,137,460...11,149,978

G

arrestin domain containing 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ARRDC4 mRNA

NCBI chr 1:131,779,436...131,793,438
Ensembl chr 1:122,369,360...122,383,290

G

agouti signaling protein

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of A mRNA

NCBI chr 3:163,933,768...164,021,377
Ensembl chr 3:143,555,696...143,561,171

G

asparagine synthetase (glutamine-hydrolyzing)

decreases expression

butylbenzyl phthalate results in decreased expression of ASNS mRNA

NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:35,785,237...35,803,423

G

astrotactin 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ASTN1 mRNA

NCBI chr13:73,070,754...73,388,902
Ensembl chr13:70,537,703...70,855,440

G

astrotactin 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ASTN2 mRNA

NCBI chr 5:78,758,142...79,744,021
Ensembl chr 5:78,758,142...79,748,273

G

activating transcription factor 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ATF3 mRNA

NCBI chr13:105,274,103...105,331,653
Ensembl chr13:102,751,321...102,764,631

G

activating transcription factor 4

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ATF4 mRNA

NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:111,804,183...111,806,446

G

ATM serine/threonine kinase

increases expression
multiple interactions

butylbenzyl phthalate results in increased expression of ATM protein
ATM protein affects the reaction [butylbenzyl phthalate results in increased expression of ZEB1 protein]

NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:53,831,093...53,932,437

G

ATPase phospholipid transporting 10D (putative)

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ATP10D mRNA

NCBI chr14:35,911,728...36,012,549
Ensembl chr14:35,912,141...36,012,564

G

ATPase Na+/K+ transporting subunit alpha 1

increases expression

butylbenzyl phthalate results in increased expression of ATP1A1 mRNA

NCBI chr 2:191,709,311...191,737,414
Ensembl chr 2:189,020,722...189,048,837

G

ATPase Na+/K+ transporting subunit alpha 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ATP1A3 mRNA

NCBI chr 1:89,700,645...89,729,782
Ensembl chr 1:80,572,796...80,601,918

G

ATPase H+ transporting V1 subunit C2

decreases expression

butylbenzyl phthalate results in decreased expression of ATP6V1C2 mRNA

NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028

G

beta 3-glucosyltransferase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of B3GLCT mRNA

NCBI chr12:10,291,910...10,383,190
Ensembl chr12:5,255,740...5,346,810

G

BCL2-antagonist/killer 1

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of BAK1 mRNA

NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,100,480...5,109,264

G

BCL2 associated X, apoptosis regulator

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of BAX protein; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of BAX protein; [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of BAX mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of BAX mRNA

PMID:28013214 PMID:35739755 PMID:37021957 PMID:37364641

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368

G

basal cell adhesion molecule (Lutheran blood group)

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of BCAM mRNA

NCBI chr 1:79,415,016...79,429,403
Ensembl chr 1:79,415,017...79,429,403

G

branched chain amino acid transaminase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of BCAT1 mRNA

NCBI chr 4:179,695,662...179,777,973
Ensembl chr 4:177,964,834...178,046,597

G

BCL2, apoptosis regulator

multiple interactions
decreases methylation
increases expression

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in decreased expression of BCL2 protein; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of BCL2 protein; [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of BCL2 mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of BCL2 mRNA
butylbenzyl phthalate results in decreased methylation of BCL2 promoter
butylbenzyl phthalate results in increased expression of BCL2 mRNA

PMID:28013214 PMID:31016752 PMID:35487445 PMID:35739755 PMID:35762964 More...

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 10

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of BCL2L10 mRNA

NCBI chr 8:84,987,833...84,993,878
Ensembl chr 8:76,107,326...76,113,367

G

BCL6, transcription repressor

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of BCL6 mRNA

NCBI chr11:90,358,753...90,382,049
Ensembl chr11:76,854,090...76,877,389

G

brain-derived neurotrophic factor

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of BDNF mRNA

NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615

G

BEN domain containing 6

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of BEND6 mRNA

NCBI chr 9:43,576,982...43,631,437
Ensembl chr 9:36,081,484...36,135,228

G

brain expressed X-linked 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of BEX2 mRNA

NCBI chr X:104,010,639...104,012,143
Ensembl chr X:99,219,014...99,220,958

G

basic helix-loop-helix family, member e40

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of BHLHE40 mRNA

NCBI chr 4:143,174,450...143,180,150
Ensembl chr 4:141,618,476...141,624,774

G

basic helix-loop-helix family, member e41

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of BHLHE41 mRNA

NCBI chr 4:178,834,264...178,838,618
Ensembl chr 4:178,834,271...178,838,468

G

betaine-homocysteine S-methyltransferase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of BHMT mRNA

NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:24,859,873...24,879,742

G

BH3 interacting domain death agonist

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of BID mRNA

NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:154,113,198...154,134,720

G

bone morphogenetic protein 6

decreases expression

butylbenzyl phthalate results in decreased expression of BMP6 mRNA

NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,318,569...26,470,365

G

BCL2 interacting protein 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of BNIP3 mRNA

NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:193,708,167...193,725,359

G

bisphosphoglycerate mutase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of BPGM mRNA

NCBI chr 4:64,106,809...64,135,749
Ensembl chr 4:63,140,018...63,168,581

G

BR serine/threonine kinase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of BRSK1 mRNA

NCBI chr 1:78,162,944...78,193,598
Ensembl chr 1:69,134,565...69,160,365

G

BTG anti-proliferation factor 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of BTG2 mRNA

NCBI chr13:48,083,931...48,087,690
Ensembl chr13:45,531,925...45,535,628

G

basic leucine zipper and W2 domains 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of BZW1 mRNA

NCBI chr 9:67,424,860...67,438,656
Ensembl chr 9:59,930,744...59,944,430

G

similar to human chromosome 21 open reading frame 91

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of D16ERTD472E mRNA

NCBI chr11:17,229,129...17,262,307
Ensembl chr11:17,229,138...17,262,483

G

complement component 4 binding protein, alpha

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in decreased expression of C4BPA mRNA

NCBI chr13:44,627,959...44,663,552
Ensembl chr13:42,075,717...42,111,205

G

complement C5

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] affects the expression of and affects the secretion of C5 protein

NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:18,270,696...18,361,994

G

calcium voltage-gated channel auxiliary subunit gamma 7

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CACNG7 mRNA

NCBI chr 1:65,800,059...65,831,246
Ensembl chr 1:65,800,355...65,831,006

G

cell adhesion molecule 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CADM3 mRNA
[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in decreased expression of CADM3 mRNA

PMID:31199487 PMID:32949613

NCBI chr13:85,784,785...85,817,412
Ensembl chr13:85,786,483...85,817,749

G

calcium dependent secretion activator

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CADPS mRNA

NCBI chr15:12,289,803...12,742,786
Ensembl chr15:12,290,262...12,742,779

G

calcium/calmodulin-dependent protein kinase IV

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CAMK4 mRNA

NCBI chr18:24,857,152...25,076,054
Ensembl chr18:24,585,269...24,802,487

G

calcium/calmodulin-dependent protein kinase kinase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CAMKK1 mRNA

NCBI chr10:58,135,872...58,159,023
Ensembl chr10:57,637,391...57,660,498

G

cullin-associated and neddylation-dissociated 2 (putative)

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CAND2 mRNA

NCBI chr 4:148,835,050...148,864,039
Ensembl chr 4:148,835,053...148,863,153

G

carbonic anhydrase 1

decreases expression

butylbenzyl phthalate results in decreased expression of CAR1 mRNA

NCBI chr 2:88,550,681...88,593,454
Ensembl chr 2:86,861,897...86,872,208

G

carbonic anhydrase 2

decreases expression

butylbenzyl phthalate results in decreased expression of CAR2 mRNA

NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:86,741,626...86,756,818

G

carbonic anhydrase 9

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in decreased expression of CA9 mRNA

NCBI chr 5:62,559,024...62,565,626
Ensembl chr 5:57,763,206...57,769,838

G

caspase 14

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in decreased expression of CASP14 mRNA

NCBI chr 7:11,577,315...11,583,987
Ensembl chr 7:10,926,725...10,933,405

G

caspase 2

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of CASP2 mRNA

NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:71,149,669...71,167,379

G

caspase 3

increases expression
multiple interactions

butylbenzyl phthalate results in increased expression of CASP3 protein alternative form
[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of CASP3 protein; [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate] results in decreased expression of CASP3 mRNA; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in increased expression of and results in increased activity of CASP3 protein; butylbenzyl phthalate results in increased expression of and results in increased activity of CASP3 protein

PMID:23220035 PMID:29029336 PMID:35739755 PMID:37839492

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648

G

caspase 8

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of CASP8 protein; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of CASP8 protein; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CASP8 mRNA

PMID:28013214 PMID:35739755 PMID:37364641

NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542

G

caspase 9

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of CASP9 protein

Ensembl chr 5:154,109,046...154,126,626

G

catalase

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of CAT mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CAT mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CAT mRNA

PMID:28013214 PMID:37364641 PMID:39150890

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478

G

cystathionine beta synthase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CBS mRNA

NCBI chr20:9,709,394...9,733,925
Ensembl chr20:9,708,090...9,732,764

G

coiled-coil domain containing 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CCDC3 mRNA

NCBI chr17:77,941,148...78,044,820
Ensembl chr17:73,035,045...73,135,337

G

C-C motif chemokine ligand 2

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of CCL2 mRNA

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 20

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in decreased expression of CCL20 mRNA

NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:84,388,904...84,391,629

G

C-C motif chemokine ligand 5

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of CCL5 mRNA

NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377

G

C-C motif chemokine ligand 9

decreases expression

butylbenzyl phthalate results in decreased expression of CCL6 mRNA

NCBI chr10:68,863,994...68,868,928
Ensembl chr10:68,366,487...68,371,369

G

cellular communication network factor 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CCN4 mRNA

NCBI chr 7:100,534,578...100,566,287
Ensembl chr 7:98,645,182...98,677,248

G

cyclin D1

multiple interactions
decreases methylation
increases expression

MIR19A mRNA affects the reaction [butylbenzyl phthalate results in increased expression of CCND1 protein]; MIR19B1 mRNA affects the reaction [butylbenzyl phthalate results in increased expression of CCND1 protein]; MIR34A mRNA inhibits the reaction [butylbenzyl phthalate results in increased expression of CCND1 protein]
butylbenzyl phthalate results in decreased methylation of CCND1 promoter
butylbenzyl phthalate results in increased expression of CCND1 mRNA; butylbenzyl phthalate results in increased expression of CCND1 protein

PMID:29864457 PMID:30243731 PMID:31016752 PMID:35487445

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602

G

cyclin D2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CCND2 mRNA

NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:159,962,363...159,989,495

G

C-C motif chemokine receptor 3

decreases expression

butylbenzyl phthalate results in decreased expression of CCR3 mRNA

NCBI chr 8:132,463,533...132,511,601
Ensembl chr 8:123,616,236...123,634,990

G

CD36 molecule

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of CD36 mRNA

NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903

G

CD93 molecule

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased secretion of CD93 protein; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CD93 mRNA

PMID:38954831 PMID:39150890

NCBI chr 3:135,891,859...135,898,378
Ensembl chr 3:135,891,859...135,898,378

G

cell division cycle 6

decreases expression

butylbenzyl phthalate results in decreased expression of CDC6 mRNA

NCBI chr10:84,360,361...84,374,239
Ensembl chr10:83,864,638...83,878,011

G

cadherin 1

decreases expression
multiple interactions

butylbenzyl phthalate results in decreased expression of CDH1 protein
[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of CDH1 protein

PMID:22552774 PMID:37364641

NCBI chr19:51,402,178...51,471,572
Ensembl chr19:34,492,371...34,561,775

G

cadherin-related family member 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CDHR1 mRNA

NCBI chr16:12,863,696...12,883,579
Ensembl chr16:12,843,437...12,863,396

G

cyclin-dependent kinase 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CDK4 mRNA

NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase 5 regulatory subunit 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CDK5R1 mRNA

NCBI chr10:65,981,692...65,985,831
Ensembl chr10:65,483,941...65,488,456

G

cyclin-dependent kinase inhibitor 1A

decreases expression
multiple interactions

butylbenzyl phthalate results in decreased expression of CDKN1A mRNA; butylbenzyl phthalate results in decreased expression of CDKN1A protein
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CDKN1A mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of CDKN1A mRNA]
MIR19A mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of CDKN1A protein]; MIR19B1 mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of CDKN1A protein]; MIR34A mRNA inhibits the reaction [butylbenzyl phthalate results in decreased expression of CDKN1A protein]

PMID:29864457 PMID:30243731 PMID:33316053 PMID:35762964

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1B

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate] results in decreased expression of CDKN1B mRNA

NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982

G

cyclin-dependent kinase inhibitor 1C

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CDKN1C mRNA

NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:198,655,407...198,658,048

G

cyclin-dependent kinase inhibitor 2A

multiple interactions
increases methylation
decreases expression

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of CDKN2A mRNA
butylbenzyl phthalate results in increased methylation of CDKN2A promoter
butylbenzyl phthalate results in decreased expression of CDKN2A mRNA

PMID:28013214 PMID:35487445

NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149

G

cysteine dioxygenase type 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CDO1 mRNA

NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296

G

CCAAT/enhancer binding protein alpha

multiple interactions

[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of CEBPA mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of CEBPA protein; [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of CEBPA mRNA; butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA]]

PMID:26820058 PMID:28595985 PMID:37021957

NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:87,759,433...87,762,412

G

cadherin, EGF LAG seven-pass G-type receptor 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CELSR3 mRNA

NCBI chr 8:118,409,136...118,438,593
Ensembl chr 8:109,530,641...109,558,354

G

centromere protein M

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CENPM mRNA

NCBI chr 7:115,628,117...115,639,401
Ensembl chr 7:113,747,516...113,764,258

G

ceramide kinase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CERK mRNA

NCBI chr 7:117,225,855...117,269,436
Ensembl chr 7:117,225,855...117,268,759

G

cilia and flagella associated protein 299

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CFAP299 mRNA

NCBI chr14:10,787,191...11,272,894
Ensembl chr14:10,787,203...11,272,943

G

complement factor D

multiple interactions

[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of CFD mRNA

NCBI chr 7:10,463,773...10,465,496
Ensembl chr 7:9,813,150...9,815,053

G

glycoprotein hormones, alpha polypeptide

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein affects the expression of ADAMTS1 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of CXCR4 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of CYP11A1 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of HSD3B2 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of PTX3 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of PGR mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of RGS2 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of STAR mRNA]; butylbenzyl phthalate inhibits the reaction [CGA protein results in increased secretion of Dinoprostone]; butylbenzyl phthalate inhibits the reaction [CGA protein results in increased secretion of Progesterone]; Cyclic AMP inhibits the reaction [[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of PGR mRNA]]
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of ADAMTS1 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of EDN2 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of MMP9 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of PGR mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of PLAT mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of ADAMTS1 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of CDKN1A mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of IL6 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of PTGS2 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of SERPINB2 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of SERPINE1 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of TIMP1 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of WNT4 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] promotes the reaction [CGA protein results in increased expression of MMP14 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] promotes the reaction [CGA protein results in increased expression of MMP16 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] promotes the reaction [CGA protein results in increased expression of SLCO2A1 mRNA]

PMID:25016925 PMID:33316053 PMID:37552060

NCBI chr 5:54,283,109...54,295,464
Ensembl chr 5:49,487,068...49,499,191

G

coiled-coil-helix-coiled-coil-helix domain containing 1

decreases expression

butylbenzyl phthalate results in decreased expression of CHCHD1 mRNA

NCBI chr15:3,592,719...3,593,901
Ensembl chr15:3,592,727...3,593,901

G

chromogranin A

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CHGA mRNA

NCBI chr 6:127,460,895...127,472,238
Ensembl chr 6:121,696,051...121,707,398

G

chromogranin B

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CHGB mRNA

NCBI chr 3:120,043,824...120,057,169
Ensembl chr 3:120,043,738...120,057,166

G

cholinergic receptor nicotinic alpha 3 subunit

decreases expression

butylbenzyl phthalate results in decreased expression of CHRNA3 mRNA

NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:55,401,702...55,415,165

G

Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CITED1 mRNA

NCBI chr X:71,390,328...71,395,023
Ensembl chr X:67,350,373...67,355,162

G

CAP-GLY domain containing linker protein 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CLIP3 mRNA

NCBI chr 1:94,674,492...94,690,643
Ensembl chr 1:85,547,206...85,563,184

G

calsyntenin 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CLSTN3 mRNA

NCBI chr 4:159,017,795...159,051,069
Ensembl chr 4:157,331,494...157,364,769

G

cytidine monophospho-N-acetylneuraminic acid hydroxylase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CMAH mRNA

NCBI chr17:40,557,161...40,642,350
Ensembl chr17:40,583,667...40,642,275

G

carboxymethylenebutenolidase homolog

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CMBL mRNA

NCBI chr 2:84,280,128...84,301,878
Ensembl chr 2:82,571,888...82,591,009

G

contactin 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CNTN2 mRNA

NCBI chr13:46,497,269...46,528,112
Ensembl chr13:43,947,265...43,975,887

G

contactin associated protein 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CNTNAP1 mRNA

NCBI chr10:86,109,850...86,125,612
Ensembl chr10:86,111,643...86,125,611

G

contactin associated protein 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CNTNAP2 mRNA

NCBI chr 4:75,109,358...77,366,258
Ensembl chr 4:74,109,472...76,362,027

G

collagen type X alpha 1 chain

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of COL10A1 mRNA

NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494

G

collagen type XVIII alpha 1 chain

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased secretion of COL18A1 protein

NCBI chr20:11,473,645...11,582,111
Ensembl chr20:11,474,104...11,582,593

G

collagen type I alpha 1 chain

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of COL1A1 mRNA

NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624

G

collagen type II alpha 1 chain

multiple interactions

[butylbenzyl phthalate co-treated with COL2A1 protein] results in increased expression of IL1B protein; [butylbenzyl phthalate co-treated with COL2A1 protein] results in increased expression of IL6 protein

NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:129,098,786...129,127,546

G

collagen type III alpha 1 chain

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of COL3A1 mRNA

NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:47,374,593...47,410,547

G

collagen type VI alpha 1 chain

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of COL6A1 mRNA

NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,957...11,924,597

G

collagen type VI alpha 2 chain

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of COL6A2 mRNA

NCBI chr20:12,021,182...12,048,932
Ensembl chr20:12,021,767...12,057,564

G

collagen type VIII alpha 1 chain

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of COL8A1 mRNA

NCBI chr11:56,245,998...56,378,586
Ensembl chr11:42,777,628...42,906,424

G

catechol-O-methyltransferase

decreases expression
multiple interactions

butylbenzyl phthalate results in decreased expression of COMT mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of COMT mRNA
fulvestrant inhibits the reaction [butylbenzyl phthalate results in decreased expression of COMT mRNA]

PMID:24040167 PMID:39150890

NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642

G

cytochrome c oxidase subunit 5B

decreases expression

butylbenzyl phthalate results in decreased expression of COX5B mRNA

NCBI chr 9:46,417,735...46,419,664
Ensembl chr 9:38,921,967...38,925,052

G

copine 8

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CPNE8 mRNA

NCBI chr 7:121,615,293...121,789,507
Ensembl chr 7:121,615,294...121,790,377

G

coproporphyrinogen oxidase

decreases expression

butylbenzyl phthalate results in decreased expression of CPOX mRNA

NCBI chr11:55,405,778...55,415,761
Ensembl chr11:41,936,591...41,946,746

G

carbamoyl-phosphate synthase 1

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in decreased expression of CPS1 mRNA

NCBI chr 9:76,063,863...76,186,739
Ensembl chr 9:68,614,153...68,737,033

G

carnitine palmitoyltransferase 1A

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in decreased expression of CPT1A mRNA

NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055

G

carnitine palmitoyltransferase 1B

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in decreased expression of CPT1B mRNA

NCBI chr 7:122,370,974...122,380,473
Ensembl chr 7:120,491,354...120,500,404

G

carnitine palmitoyltransferase 2

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in decreased expression of CPT2 mRNA

NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:122,664,677...122,682,095

G

carboxypeptidase Z

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CPZ mRNA

NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945

G

cellular repressor of E1A-stimulated genes 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CREG1 mRNA

NCBI chr13:80,552,779...80,565,272
Ensembl chr13:78,019,843...78,032,308

G

corticotropin releasing hormone

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CRH mRNA

NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:102,143,055...102,144,919

G

corticotropin releasing hormone receptor 1

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CRHR1 mRNA

NCBI chr10:89,540,192...89,583,466
Ensembl chr10:89,040,203...89,083,481

G

cysteine-rich secretory protein 1

decreases expression

butylbenzyl phthalate results in decreased expression of CRISP1 mRNA

NCBI chr 9:28,238,326...28,265,344
Ensembl chr 9:20,741,777...20,768,796

G

collapsin response mediator protein 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CRMP1 mRNA

NCBI chr14:73,509,933...73,556,192
Ensembl chr14:73,509,933...73,556,177

G

C-reactive protein

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of CRP protein
[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in decreased expression of CRP mRNA

PMID:32949613 PMID:38954831

NCBI chr13:87,694,062...87,695,978
Ensembl chr13:85,124,977...85,175,178

G

colony stimulating factor 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] affects the expression of and affects the secretion of CSF1 protein

NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:195,377,215...195,411,704

G

cysteine and serine rich nuclear protein 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CSRNP1 mRNA

NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183

G

catenin beta 1

affects localization
increases acetylation
multiple interactions

butylbenzyl phthalate affects the localization of CTNNB1 protein
butylbenzyl phthalate results in increased acetylation of CTNNB1 protein
HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate affects the localization of CTNNB1 protein]; trichostatin A inhibits the reaction [butylbenzyl phthalate affects the localization of CTNNB1 protein]

PMID:22552774 PMID:27923775

NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111

G

C-X-C motif chemokine ligand 12

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] affects the expression of and affects the secretion of CXCL12 protein

NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:150,388,325...150,401,168

G

C-X-C motif chemokine ligand 13

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] affects the expression of and affects the secretion of CXCL13 protein
[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in decreased expression of CXCL13 mRNA

PMID:32949613 PMID:38954831

NCBI chr14:13,912,858...13,917,920
Ensembl chr14:13,608,902...13,613,933

G

C-X-C motif chemokine ligand 3

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of CXCL1 mRNA

NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,270,146...17,289,511

G

C-X-C motif chemokine ligand 9

decreases expression

butylbenzyl phthalate results in decreased expression of CXCL9 mRNA

NCBI chr14:16,007,166...16,012,077
Ensembl chr14:15,722,908...15,728,435

G

C-X-C motif chemokine receptor 4

multiple interactions
increases expression

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of CXCR4 mRNA]
butylbenzyl phthalate results in increased expression of CXCR4 mRNA

PMID:32308655 PMID:37552060

NCBI chr13:42,630,383...42,634,288
Ensembl chr13:40,077,976...40,081,883

G

cytochrome b5 type A

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CYB5A mRNA

NCBI chr18:80,487,923...80,520,544
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535

G

cytochrome b-245 alpha chain

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of CYBA mRNA

NCBI chr19:67,396,143...67,404,214
Ensembl chr19:50,487,597...50,495,721

G

cytochrome b-245 beta chain

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of CYBB mRNA

NCBI chr X:16,030,596...16,065,065
Ensembl chr X:13,359,430...13,392,586

G

cytochrome c, somatic

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of CYCS protein

NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054

G

cytochrome P450, family 11, subfamily a, polypeptide 1

increases expression
multiple interactions

butylbenzyl phthalate results in increased expression of CYP11A1 mRNA; butylbenzyl phthalate results in increased expression of CYP11A1 protein
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of CYP11A1 mRNA]
[diisobutyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate] results in decreased expression of CYP11A1 mRNA
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CYP11A1 mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CYP11A1 mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CYP11A1 mRNA; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP11A1 mRNA; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diethyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased expression of CYP11A1 mRNA; [Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate] results in decreased expression of CYP11A1 mRNA; [dimethyl phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate] results in decreased expression of CYP11A1 mRNA

PMID:26472102 PMID:28013214 PMID:29029336 PMID:30802670 PMID:31319113 More...

NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:58,404,669...58,434,338

G

cytochrome P450, family 11, subfamily b, polypeptide 2

decreases expression

butylbenzyl phthalate results in decreased expression of CYP11B1 mRNA

NCBI chr 7:108,719,349...108,726,024
Ensembl chr 7:106,838,590...106,845,004

G

cytochrome P450, family 11, subfamily b, polypeptide 3

decreases expression

butylbenzyl phthalate results in decreased expression of CYP11B2 mRNA

NCBI chr 7:108,689,319...108,694,808
Ensembl chr 7:106,808,559...106,814,048

G

cytochrome P450, family 17, subfamily a, polypeptide 1

decreases expression
multiple interactions

butylbenzyl phthalate results in decreased expression of CYP17A1 mRNA
[diisobutyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate] results in decreased expression of CYP17A1 mRNA
[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in increased expression of CYP17A1 mRNA; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diethyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased expression of CYP17A1 mRNA

PMID:26472102 PMID:29029336 PMID:30802670 PMID:33983380 PMID:37788136

NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:245,535,462...245,541,573

G

cytochrome P450, family 19, subfamily a, polypeptide 1

multiple interactions
increases expression
decreases expression
decreases activity

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CYP19A1 mRNA; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP19A1 mRNA; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP19A1 protein; [Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate] results in decreased expression of CYP19A1 mRNA; schizandrin B inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP19A1 mRNA]; schizandrin B inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP19A1 protein]
butylbenzyl phthalate results in increased expression of CYP19A1 mRNA; butylbenzyl phthalate results in increased expression of CYP19A1 protein
butylbenzyl phthalate results in increased expression of and results in increased activity of CYP19A1 protein; Fulvestrant inhibits the reaction [butylbenzyl phthalate results in increased activity of CYP19A1 protein]
butylbenzyl phthalate results in decreased expression of CYP19A1 mRNA; butylbenzyl phthalate results in decreased expression of CYP19A1 protein
butylbenzyl phthalate results in decreased activity of CYP19A1 protein

PMID:27825933 PMID:28013214 PMID:29029336 PMID:31016752 PMID:34597818 More...

NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:54,553,165...54,580,758

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression
decreases activity

butylbenzyl phthalate results in increased expression of CYP1A1 protein
butylbenzyl phthalate results in decreased activity of CYP1A1 protein

PMID:22138065 PMID:27432241

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily a, polypeptide 2

decreases activity

butylbenzyl phthalate results in decreased activity of CYP1A2 protein

NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 1, subfamily b, polypeptide 1

multiple interactions
increases expression

3',4'-dimethoxyflavone inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 protein]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 mRNA]; AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 protein]; butylbenzyl phthalate promotes the reaction [AHR protein binds to CYP1B1 promoter]
schizandrin B inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 mRNA]
butylbenzyl phthalate results in increased expression of CYP1B1 mRNA; butylbenzyl phthalate results in increased expression of CYP1B1 protein

PMID:22138065 PMID:38227285

NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 26, subfamily b, polypeptide 1

multiple interactions

[diisobutyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate] results in increased expression of CYP26B1 mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CYP26B1 mRNA

PMID:37788136 PMID:39150890

NCBI chr 4:118,599,356...118,616,176
Ensembl chr 4:117,041,808...117,058,628

G

cytochrome P450, family 27, subfamily a, polypeptide 1

increases expression

butylbenzyl phthalate results in increased expression of CYP27A1 mRNA

NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:76,264,860...76,294,551

G

cytochrome P450, family 2, subfamily b, polypeptide 1

decreases activity

butylbenzyl phthalate results in decreased activity of CYP2B1 protein

NCBI chr 1:90,646,098...90,669,762
Ensembl chr 1:81,518,408...81,542,052

G

cytochrome P450, family 2, subfamily b, polypeptide 3

increases expression

butylbenzyl phthalate results in increased expression of CYP2B10 mRNA

NCBI chr 1:90,780,468...90,859,852
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, subfamily 2, polypeptide 11

decreases activity

butylbenzyl phthalate results in decreased activity of CYP2C11 protein

NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:236,762,842...236,799,066

G

cytochrome P450, family 2, subfamily e, polypeptide 1

decreases activity

butylbenzyl phthalate results in decreased activity of CYP2E1 protein

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 2, subfamily f, polypeptide 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of CYP2F2 mRNA

NCBI chr 1:91,543,768...91,557,553
Ensembl chr 1:82,416,130...82,429,896

G

cytochrome P450, family 3, subfamily a, polypeptide 2

increases expression

butylbenzyl phthalate results in increased expression of CYP3A4 protein

NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 3, subfamily a, polypeptide 62

decreases activity

butylbenzyl phthalate results in decreased activity of CYP3A62 protein

NCBI chr12:21,511,763...21,547,598
Ensembl chr12:16,397,998...16,433,833

G

cytochrome P450, family 4, subfamily f, polypeptide 18

multiple interactions

[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate] affects the expression of CYP4F18 protein

NCBI chr16:17,797,558...17,838,958
Ensembl chr16:17,707,317...17,804,940

G

cytochrome P450, family 51

decreases expression

butylbenzyl phthalate results in decreased expression of CYP51 mRNA

NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,036,865...30,055,410
Ensembl chr 6:30,036,865...30,055,410

G

differentiation antagonizing non-protein coding RNA

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of DANCR mRNA

NCBI chr14:34,126,956...34,127,936

G

DDB1 and CUL4 associated factor 12-like 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of DCAF12L1 mRNA

NCBI chr X:128,572,969...128,576,588
Ensembl chr X:123,695,286...123,698,905

G

doublecortin-like kinase 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of DCLK3 mRNA

NCBI chr 8:111,401,544...111,453,999
Ensembl chr 8:111,401,358...111,453,999

G

dopa decarboxylase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of DDC mRNA

NCBI chr14:90,592,304...90,682,830
Ensembl chr14:86,378,685...86,469,208

G

DNA-damage inducible transcript 3

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of DDIT3 mRNA

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201

G

DNA-damage-inducible transcript 4

increases expression

butylbenzyl phthalate results in increased expression of DDIT4 mRNA

NCBI chr20:28,434,938...28,437,037
Ensembl chr20:27,891,998...27,894,105

G

DNA-damage-inducible transcript 4-like

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of DDIT4L mRNA

NCBI chr 2:228,800,831...228,804,478
Ensembl chr 2:226,128,276...226,131,375

G

diacylglycerol kinase, beta

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of DGKB mRNA

NCBI chr 6:60,368,101...61,124,420
Ensembl chr 6:54,641,614...55,397,043

G

D-glutamate cyclase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of DGLUCY mRNA

NCBI chr 6:125,785,075...125,860,496
Ensembl chr 6:120,055,460...120,130,910

G

7-dehydrocholesterol reductase

decreases expression

butylbenzyl phthalate results in decreased expression of DHCR7 mRNA

NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:199,015,081...199,031,055

G

dehydrogenase/reductase 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of DHRS3 mRNA

NCBI chr 5:162,031,853...162,065,655
Ensembl chr 5:156,747,962...156,782,417

G

DEAH-box helicase 8

multiple interactions

[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate] affects the expression of DHX8 protein

NCBI chr10:87,167,861...87,204,426
Ensembl chr10:86,667,834...86,705,137

G

dicer 1 ribonuclease III

multiple interactions

[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with nonylphenol co-treated with octylphenol] results in increased expression of DICER1 mRNA

NCBI chr 6:129,392,298...129,457,252
Ensembl chr 6:123,631,250...123,693,965

G

dickkopf WNT signaling pathway inhibitor 1

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in decreased expression of DKK1 mRNA

NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:228,381,521...228,385,202

G

dickkopf WNT signaling pathway inhibitor 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of DKK2 mRNA

NCBI chr 2:223,242,375...223,334,249
Ensembl chr 2:220,568,338...220,660,225

G

dynein axonemal assembly factor 10

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of WDR92 mRNA

NCBI chr14:91,618,649...91,639,828
Ensembl chr14:91,636,157...91,639,831

G

delta/notch-like EGF repeat containing

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of DNER mRNA

NCBI chr 9:93,035,108...93,350,568
Ensembl chr 9:85,586,987...85,902,637

G

dedicator of cyto-kinesis 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of DOCK3 mRNA

NCBI chr 8:107,552,462...107,903,527
Ensembl chr 8:107,552,463...107,903,514

G

double PHD fingers 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of DPF1 mRNA

NCBI chr 1:84,602,212...84,615,954
Ensembl chr 1:84,602,336...84,615,950

G

dermatopontin

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in decreased expression of DPT mRNA

NCBI chr13:79,656,341...79,684,759
Ensembl chr13:77,123,115...77,151,639

G

dihydropyrimidinase-like 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of DPYSL3 mRNA

NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157

G

dopamine receptor D4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of DRD4 mRNA

NCBI chr 1:205,825,937...205,829,124
Ensembl chr 1:196,396,366...196,399,553

G

drosha ribonuclease III

multiple interactions

[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with nonylphenol co-treated with octylphenol] results in increased expression of DROSHA mRNA; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with nonylphenol co-treated with octylphenol] results in increased expression of DROSHA protein

NCBI chr 2:63,591,885...63,703,688
Ensembl chr 2:61,864,970...61,976,688

G

dual specificity phosphatase 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of DUSP4 mRNA

NCBI chr16:64,079,893...64,101,396
Ensembl chr16:57,377,229...57,398,138

G

dynein cytoplasmic 1 intermediate chain 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of DYNC1I1 mRNA

NCBI chr 4:34,819,313...35,132,647
Ensembl chr 4:33,852,927...34,166,149

G

EBP, cholestenol delta-isomerase

decreases expression

butylbenzyl phthalate results in decreased expression of EBP mRNA

NCBI chr X:16,971,372...16,977,782
Ensembl chr X:14,299,448...14,305,826

G

endothelin-converting enzyme 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ECE2 mRNA

NCBI chr11:80,259,130...80,278,446
Ensembl chr11:80,263,162...80,278,428

G

endothelin 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of EDN1 mRNA

NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,454,420...22,460,885

G

endothelin 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of EDN2 mRNA]

NCBI chr 5:139,036,576...139,042,074
Ensembl chr 5:133,751,217...133,756,814

G

epidermal growth factor receptor

multiple interactions
increases phosphorylation

fulvestrant inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of EGFR protein]

NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382

G

early growth response 1

multiple interactions
increases expression

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of EGR1 mRNA
butylbenzyl phthalate results in increased expression of EGR1 mRNA

PMID:32308655 PMID:39150890

NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766

G

ELAV like RNA binding protein 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ELAVL2 mRNA

NCBI chr 5:105,960,872...106,086,463
Ensembl chr 5:105,960,875...106,109,097

G

ELMO domain containing 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ELMOD1 mRNA

NCBI chr 8:54,298,363...54,355,348
Ensembl chr 8:54,298,363...54,355,140

G

embigin

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of EMB mRNA

NCBI chr 2:50,803,468...50,858,001
Ensembl chr 2:49,069,087...49,125,050

G

epithelial membrane protein 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of EMP2 mRNA

NCBI chr10:5,866,869...5,901,533
Ensembl chr10:5,360,073...5,394,733

G

empty spiracles homeobox 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of EMX2 mRNA

NCBI chr 1:258,626,584...258,633,594
Ensembl chr 1:258,626,584...258,633,594

G

ectodermal-neural cortex 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ENC1 mRNA

NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713

G

ependymin related 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of EPDR1 mRNA

NCBI chr17:50,029,591...50,054,254
Ensembl chr17:45,333,956...45,358,594

G

Eph receptor A4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of EPHA4 mRNA

NCBI chr 9:86,263,982...86,406,744
Ensembl chr 9:78,815,460...78,958,139

G

endoplasmic reticulum metallopeptidase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ERMP1 mRNA

NCBI chr 1:236,801,459...236,835,656
Ensembl chr 1:227,387,920...227,436,909

G

endoplasmic reticulum to nucleus signaling 1

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ERN1 mRNA; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ERN1 protein

NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029

G

ERBB receptor feedback inhibitor 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ERRFI1 mRNA

NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:161,323,998...161,337,282

G

espin

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ESPN mRNA

NCBI chr 5:162,626,560...162,660,439
Ensembl chr 5:162,626,560...162,660,256

G

estrogen receptor 1

multiple interactions
decreases expression
increases activity
affects binding
decreases methylation

butylbenzyl phthalate binds to and results in increased activity of ESR1 protein; butylbenzyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR1 protein]; Oxygen deficiency promotes the reaction [butylbenzyl phthalate results in decreased expression of ESR1 mRNA]; Oxygen deficiency promotes the reaction [butylbenzyl phthalate results in decreased expression of ESR1 protein]; Tamoxifen inhibits the reaction [butylbenzyl phthalate binds to and results in increased activity of ESR1 protein]
[Zeranol co-treated with butylbenzyl phthalate] affects the expression of ESR1 protein
butylbenzyl phthalate results in decreased expression of ESR1 mRNA; butylbenzyl phthalate results in decreased expression of ESR1 protein
butylbenzyl phthalate results in increased activity of ESR1 protein
[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ESR1 protein; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ESR1 protein; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ESR1 mRNA
butylbenzyl phthalate binds to ESR1 protein
butylbenzyl phthalate results in decreased methylation of ESR1 gene; butylbenzyl phthalate results in decreased methylation of ESR1 promoter

PMID:15840436 PMID:16326419 PMID:19913605 PMID:20822795 PMID:22467034 More...

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

multiple interactions
increases expression
increases activity
affects binding

butylbenzyl phthalate binds to and results in decreased activity of ESR2 protein; butylbenzyl phthalate binds to and results in increased activity of ESR2 protein; butylbenzyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]
butylbenzyl phthalate results in increased expression of ESR2 mRNA
[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ESR2 protein; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ESR2 protein; [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ESR2 mRNA
butylbenzyl phthalate results in increased activity of ESR2 protein
butylbenzyl phthalate binds to ESR2 protein

PMID:15840436 PMID:19913605 PMID:28571686 PMID:31016752 PMID:32518293 More...

NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919

G

extended synaptotagmin 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ESYT1 mRNA

NCBI chr 7:928,848...946,199
Ensembl chr 7:928,848...946,199

G

electron transfer flavoprotein dehydrogenase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ETFDH mRNA

NCBI chr 2:167,038,707...167,060,758
Ensembl chr 2:164,729,749...164,762,745

G

ETS proto-oncogene 1, transcription factor

multiple interactions

butylbenzyl phthalate promotes the reaction [ETS1 protein binds to MMP3 promoter]; butylbenzyl phthalate promotes the reaction [NR1I2 protein binds to ETS1 protein]; butylbenzyl phthalate results in increased localization of and results in increased activity of ETS1 protein

NCBI chr 8:39,303,936...39,426,022
Ensembl chr 8:31,045,945...31,168,010

G

ETS variant transcription factor 5

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ETV5 mRNA

NCBI chr11:92,113,171...92,170,758
Ensembl chr11:78,608,710...78,666,215

G

eva-1 homolog A, regulator of programmed cell death

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of EVA1A mRNA

NCBI chr 4:114,593,773...114,643,011
Ensembl chr 4:114,593,341...114,643,011

G

EYA transcriptional coactivator and phosphatase 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of EYA2 mRNA

NCBI chr 3:174,754,772...174,938,035
Ensembl chr 3:154,335,400...154,518,793

G

fatty acid binding protein 4

increases expression
multiple interactions

butylbenzyl phthalate results in increased expression of FABP4 mRNA
[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of FABP4 mRNA

PMID:24155963 PMID:26820058 PMID:27923775 PMID:34520170

NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:91,580,885...91,585,578

G

fatty acid binding protein 5

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of FABP5 mRNA

NCBI chr 2:93,672,451...93,676,186
Ensembl chr 2:91,765,056...91,853,773

G

fatty acid desaturase 3

decreases expression

butylbenzyl phthalate results in decreased expression of FADS3 mRNA

NCBI chr 1:206,685,667...206,702,538
Ensembl chr 1:206,685,894...206,704,769

G

fumarylacetoacetate hydrolase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of FAH mRNA

NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505

G

family with sequence similarity 163, member A

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of FAM163A mRNA

NCBI chr13:68,262,867...68,341,323
Ensembl chr13:68,262,872...68,341,049

G

family with sequence similarity 219, member A

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of FAM219A mRNA

NCBI chr 5:56,679,272...56,729,959
Ensembl chr 5:56,680,613...56,729,924

G

family with sequence similarity 222, member A

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of FAM222A mRNA

NCBI chr12:41,982,064...42,033,085
Ensembl chr12:41,986,780...42,033,682

G

fatty acyl CoA reductase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of FAR1 mRNA

NCBI chr 1:167,644,622...167,705,868
Ensembl chr 1:167,644,677...167,705,730

G

Fas cell surface death receptor

multiple interactions

[butylbenzyl phthalate co-treated with Dietary Fats] results in increased expression of FAS mRNA

NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591

G

fatty acid synthase

multiple interactions

[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of FASN mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of FASN protein; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of FASN mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of FASN mRNA

PMID:26820058 PMID:31240115 PMID:35739755

NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261

G

F-box and leucine-rich repeat protein 7

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of FBXL7 mRNA

NCBI chr 2:78,870,236...79,239,697
Ensembl chr 2:77,140,826...77,509,223

G

Fc gamma receptor 2A

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of FCGR3 mRNA

NCBI chr13:85,813,516...85,830,269
Ensembl chr13:83,280,784...83,295,967

G

fasciculation and elongation protein zeta 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of FEZ1 mRNA

NCBI chr 8:44,733,288...44,778,519
Ensembl chr 8:36,544,535...36,589,683

G

fibroblast growth factor 11

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of FGF11 mRNA

NCBI chr10:55,015,232...55,020,773
Ensembl chr10:54,517,077...54,522,062

G

fibroblast growth factor 2

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of FGF2 mRNA

NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:120,236,328...120,291,221

G

fibroblast growth factor 5

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of FGF5 mRNA

NCBI chr14:11,627,906...11,650,243
Ensembl chr14:11,325,334...11,345,997

G

fibroblast growth factor receptor 2

decreases expression
multiple interactions

butylbenzyl phthalate results in decreased expression of FGFR2 mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of FGFR2 mRNA

PMID:26472102 PMID:39150890

NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:184,745,420...184,850,626

G

four and a half LIM domains 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of FHL2 mRNA

NCBI chr 9:52,881,091...52,954,540
Ensembl chr 9:45,388,981...45,431,192

G

FKBP prolyl isomerase 1B

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of FKBP1B mRNA

NCBI chr 6:33,551,583...33,570,055
Ensembl chr 6:27,838,802...27,848,653

G

FKBP prolyl isomerase 5

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of FKBP5 mRNA

NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,457,216...6,541,674

G

folliculin

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of FLCN mRNA

NCBI chr10:45,088,164...45,107,581
Ensembl chr10:44,588,624...44,607,769

G

filaggrin

multiple interactions

[FLG gene polymorphism affects the susceptibility to butylbenzyl phthalate] which affects the abundance of mono-benzyl phthalate

NCBI chr 2:178,884,793...178,912,986

G

FosB proto-oncogene, AP-1 transcription factor subunit

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of FOSB mRNA

NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:78,954,115...78,961,465

G

forkhead box O1

multiple interactions

butylbenzyl phthalate results in increased expression of and results in increased acetylation of FOXO1 protein

NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:136,312,168...136,387,790

G

fibronectin type III and SPRY domain containing 2

increases expression
decreases expression

butylbenzyl phthalate results in increased expression of FSD2 mRNA
butylbenzyl phthalate results in decreased expression of FSD2 mRNA

NCBI chr 1:135,484,002...135,522,517
Ensembl chr 1:135,489,266...135,522,472

G

follicle stimulating hormone subunit beta

multiple interactions
increases expression

butylbenzyl phthalate promotes the reaction [Dibutyl Phthalate results in increased expression of FSHB protein]
[Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate] results in decreased expression of FSHB protein
butylbenzyl phthalate results in increased expression of FSHB protein

PMID:29969652 PMID:34597818

NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:93,548,560...93,552,370

G

follicle stimulating hormone receptor

multiple interactions
increases expression

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of FSHR mRNA
butylbenzyl phthalate results in increased expression of FSHR mRNA; butylbenzyl phthalate results in increased expression of FSHR protein

PMID:28013214 PMID:31319113

NCBI chr 6:10,952,329...11,160,288
Ensembl chr 6:5,198,825...5,406,785

G

FXYD domain-containing ion transport regulator 7

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of FXYD7 mRNA

NCBI chr 1:95,405,071...95,414,407
Ensembl chr 1:86,277,678...86,286,954

G

frizzled class receptor 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of FZD2 mRNA

NCBI chr10:88,061,988...88,063,898
Ensembl chr10:87,561,326...87,565,334

G

frizzled class receptor 8

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of FZD8 mRNA

NCBI chr17:62,007,849...62,015,485
Ensembl chr17:57,314,450...57,320,650

G

GA binding protein transcription factor subunit beta 1

decreases expression

butylbenzyl phthalate results in decreased expression of GABPB1 mRNA

NCBI chr 3:134,333,339...134,380,239
Ensembl chr 3:113,879,973...113,923,696

G

growth arrest and DNA-damage-inducible, alpha

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GADD45A mRNA

NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:96,154,789...96,157,115

G

polypeptide N-acetylgalactosaminyltransferase 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GALNT4 mRNA

NCBI chr 7:35,811,904...35,814,445

G

glucosidase II alpha subunit

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GANAB mRNA

NCBI chr 1:205,793,910...205,813,704
Ensembl chr 1:205,793,895...205,813,695

G

GATA binding protein 4

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of GATA4 mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GATA4 mRNA

PMID:37364641 PMID:39150890

NCBI chr15:41,635,572...41,707,252
Ensembl chr15:37,459,601...37,505,636

G

glutamate-cysteine ligase, catalytic subunit

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of GCLC mRNA

NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544

G

growth differentiation factor 15

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GDF15 mRNA

NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,805,239...18,808,055

G

growth factor independent 1B transcriptional repressor

decreases expression

butylbenzyl phthalate results in decreased expression of GFI1B mRNA

NCBI chr 3:32,338,213...32,350,963
Ensembl chr 3:11,940,233...11,952,942

G

GDNF family receptor alpha 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of GFRA3 mRNA

NCBI chr18:26,297,828...26,326,105
Ensembl chr18:26,297,829...26,326,105

G

GDNF family receptor alpha 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of GFRA4 mRNA

NCBI chr 3:118,254,937...118,262,252
Ensembl chr 3:118,255,402...118,258,329

G

gamma-glutamyltransferase 1

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of GGT1 protein

NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,700...13,108,442

G

glycoprotein alpha-galactosyltransferase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of GGTA1 mRNA

NCBI chr 3:18,732,985...18,824,916
Ensembl chr 3:18,732,991...18,809,908

G

glycerol kinase

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of GK mRNA

NCBI chr X:54,106,708...54,189,940
Ensembl chr X:50,163,123...50,238,631

G

GLI pathogenesis-related 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GLIPR2 mRNA

NCBI chr 5:62,966,163...62,998,016
Ensembl chr 5:58,170,425...58,202,272

G

glutaminase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GLS mRNA

NCBI chr 9:56,836,584...56,908,861
Ensembl chr 9:49,344,781...49,416,900

G

glutaminase 2

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of GLS2 mRNA

NCBI chr 7:1,201,757...1,218,014
Ensembl chr 7:617,288...633,426

G

glucocorticoid modulatory element binding protein 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GMEB1 mRNA

NCBI chr 5:144,421,151...144,462,448
Ensembl chr 5:144,420,555...144,462,602

G

G protein subunit gamma 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of GNG2 mRNA

NCBI chr15:4,365,222...4,466,060
Ensembl chr15:4,316,059...4,417,183

G

glutamic-oxaloacetic transaminase 1

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of GOT1 protein

NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:242,357,306...242,380,633

G

glycerol-3-phosphate acyltransferase, mitochondrial

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of GPAM mRNA

NCBI chr 1:264,111,599...264,176,112
Ensembl chr 1:254,106,331...254,142,639

G

glycerophosphocholine phosphodiesterase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GPCPD1 mRNA

NCBI chr 3:140,240,574...140,285,469
Ensembl chr 3:119,787,682...119,832,517

G

glycerol-3-phosphate dehydrogenase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GPD1 mRNA

NCBI chr 7:132,722,982...132,730,373
Ensembl chr 7:130,844,138...130,851,529

G

G protein-coupled estrogen receptor 1

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of GPER1 protein; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of GPER1 mRNA

PMID:35739755 PMID:37364641

NCBI chr12:20,331,073...20,336,527
Ensembl chr12:15,217,442...15,221,889

G

glucose-6-phosphate isomerase

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of GPI1 mRNA

NCBI chr 1:95,965,389...95,996,932
Ensembl chr 1:86,828,216...86,856,086

G

G protein-coupled receptor 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GPR3 mRNA

NCBI chr 5:150,695,406...150,698,526
Ensembl chr 5:145,411,510...145,414,590

G

G protein regulated inducer of neurite outgrowth 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GPRIN2 mRNA

NCBI chr16:9,496,452...9,512,672
Ensembl chr16:9,505,643...9,507,010

G

glutamic--pyruvic transaminase

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of GPT protein

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494

G

glutathione peroxidase 1

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of GPX1 mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of GPX1 mRNA

PMID:28013214 PMID:37021957

NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024

G

GRAM domain containing 1B

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GRAMD1B mRNA

NCBI chr 8:40,654,492...40,893,869
Ensembl chr 8:40,659,182...40,893,925

G

growth factor receptor bound protein 14

increases expression

butylbenzyl phthalate results in increased expression of GRB14 mRNA

NCBI chr 3:69,976,331...70,091,921
Ensembl chr 3:49,568,210...49,683,889

G

growth regulating estrogen receptor binding 1

increases expression

butylbenzyl phthalate results in increased expression of GREB1 mRNA

NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633

G

gremlin 2, DAN family BMP antagonist

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GREM2 mRNA

NCBI chr13:89,310,897...89,403,856
Ensembl chr13:86,778,500...86,871,615

G

glutamate ionotropic receptor NMDA type subunit 2B

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GRIN2B mRNA

NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:168,599,546...169,042,279

G

glycogen synthase kinase 3 beta

multiple interactions
increases phosphorylation

HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of GSK3B protein]

NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646

G

glutathione-disulfide reductase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of GSR mRNA

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661

G

glutathione S-transferase alpha 2

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in increased expression of GSTA2 mRNA

NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase alpha 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of GSTA3 mRNA

NCBI chr 9:31,154,989...31,180,653
Ensembl chr 9:23,658,574...23,684,240

G

granzyme A

decreases expression

butylbenzyl phthalate results in decreased expression of GZMA mRNA

NCBI chr 2:46,473,763...46,485,696
Ensembl chr 2:44,740,569...44,752,493

G

H19 imprinted maternally expressed transcript

decreases expression

butylbenzyl phthalate results in decreased expression of H19 mRNA

NCBI chr 1:207,160,175...207,162,851
Ensembl chr 1:197,730,698...197,733,134

G

H2A.X variant histone

multiple interactions
increases phosphorylation

Nicotinamide Mononucleotide inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of H2AX protein]

NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239

G

H3.3 histone B

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of H3F3B mRNA

NCBI chr10:101,755,404...101,764,616
Ensembl chr10:101,256,480...101,258,709
Ensembl chr13:101,256,480...101,258,709

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of HADHA mRNA

NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:26,187,956...26,227,869

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of HADHB mRNA

NCBI chr 6:31,873,404...31,907,557
Ensembl chr 6:26,153,578...26,184,869

G

hyaluronan synthase 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of HAS2 mRNA

NCBI chr 7:90,002,929...90,028,933
Ensembl chr 7:88,113,326...88,128,933

G

HCK proto-oncogene, Src family tyrosine kinase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of HCK mRNA

NCBI chr 3:162,031,833...162,074,933
Ensembl chr 3:141,571,587...141,614,693

G

histone deacetylase 6

multiple interactions
increases response to substance
increases expression

[butylbenzyl phthalate promotes the reaction [TFAP2A protein binds to HDAC6 promoter]] which results in increased expression of HDAC6 mRNA; butylbenzyl phthalate promotes the reaction [TFAP2A protein binds to HDAC6 promoter]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate affects the localization of CTNNB1 protein]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate results in decreased expression of KRT7 protein]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of VIM protein]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of AKT1 protein]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of GSK3B protein]; TFAP2A mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of HDAC6 protein]
HDAC6 results in increased susceptibility to butylbenzyl phthalate
butylbenzyl phthalate results in increased expression of HDAC6 mRNA; butylbenzyl phthalate results in increased expression of HDAC6 protein

NCBI chr X:17,222,538...17,244,373
Ensembl chr X:14,551,044...14,572,441

G

heme binding protein 1

decreases expression

butylbenzyl phthalate results in decreased expression of HEBP1 mRNA

NCBI chr 4:167,974,316...168,003,854
Ensembl chr 4:167,974,319...168,003,854

G

hes-related family bHLH transcription factor with YRPW motif 1

decreases expression

butylbenzyl phthalate results in decreased expression of HEY1 mRNA

NCBI chr 2:95,003,935...95,006,457
Ensembl chr 2:93,095,498...93,100,312

G

hexokinase 1

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of HK1 mRNA

NCBI chr20:30,773,222...30,874,814
Ensembl chr20:30,230,486...30,332,131

G

high mobility group box 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of HMGB2 mRNA

NCBI chr16:37,721,374...37,723,950
Ensembl chr16:32,710,658...32,713,140
Ensembl chr 1:32,710,658...32,713,140

G

3-hydroxy-3-methylglutaryl-CoA reductase

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of HMGCR mRNA; [butylbenzyl phthalate co-treated with Dietary Fats] results in increased expression of HMGCR mRNA

PMID:32905190 PMID:35739755

NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of HMGCS1 mRNA

NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:51,649,497...51,667,100

G

heme oxygenase 1

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of HMOX1 mRNA

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079

G

HNF1 homeobox A

decreases expression

butylbenzyl phthalate results in decreased expression of HNF1A mRNA

NCBI chr12:47,299,171...47,333,457
Ensembl chr12:41,645,587...41,672,104

G

homeo box B8

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of HOXB8 mRNA

NCBI chr10:81,248,313...81,251,261
Ensembl chr10:81,248,887...81,250,638

G

homeo box D3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of HOXD3 mRNA

NCBI chr 3:80,041,598...80,057,700
Ensembl chr 3:59,638,708...59,650,282

G

haptoglobin

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of HP mRNA

NCBI chr19:54,449,151...54,453,701
Ensembl chr19:37,539,627...37,544,523

G

15-hydroxyprostaglandin dehydrogenase

multiple interactions

[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate] results in increased expression of HPGD mRNA; [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate] results in increased expression of HPGD protein

NCBI chr16:38,996,876...39,034,831
Ensembl chr16:33,986,266...34,024,228

G

hydroxysteroid 11-beta dehydrogenase 1

increases expression

butylbenzyl phthalate results in increased expression of HSD11B1 protein

NCBI chr13:107,277,526...107,327,462
Ensembl chr13:104,728,539...104,788,687

G

hydroxysteroid (17-beta) dehydrogenase 11

increases expression
multiple interactions

butylbenzyl phthalate results in increased expression of HSD17B11 mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of HSD17B11 mRNA

PMID:26472102 PMID:39150890

NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161

G

hydroxysteroid (17-beta) dehydrogenase 8

increases expression

butylbenzyl phthalate results in increased expression of HSD17B8 mRNA

PMID:19560483 PMID:26472102

NCBI chr20:4,826,725...4,828,742
Ensembl chr20:4,822,026...4,828,742

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

multiple interactions
increases expression

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of HSD3B1 mRNA; [dimethyl phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate] results in increased expression of HSD3B1 mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of HSD3B1 mRNA
butylbenzyl phthalate results in increased expression of HSD3B1 mRNA; butylbenzyl phthalate results in increased expression of HSD3B1 protein

PMID:28013214 PMID:31319113 PMID:35739735 PMID:35762964

NCBI chr 2:188,858,574...188,864,694
Ensembl chr 2:186,169,863...186,175,999

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of HSD3B2 mRNA]

NCBI chr 2:188,784,614...188,812,535
Ensembl chr 2:186,095,897...186,101,852

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3

decreases expression

butylbenzyl phthalate results in decreased expression of HSD3B3 mRNA

NCBI chr 2:186,138,044...186,144,024
Ensembl chr 2:186,138,044...186,144,033

G

hydroxysteroid dehydrogenase like 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of HSDL2 mRNA

NCBI chr 5:79,238,881...79,274,051
Ensembl chr 5:74,443,872...74,479,839

G

heat shock protein 90 beta family member 1

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of HSP90B1 mRNA

NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:21,110,457...21,124,788

G

heat shock protein family A (Hsp70) member 12A

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of HSPA12A mRNA

NCBI chr 1:257,935,642...258,096,602
Ensembl chr 1:257,935,644...258,096,846

G

heat shock protein family A (Hsp70) member 5

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of HSPA5 mRNA; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of HSPA5 protein

NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891

G

heat shock protein family B (small) member 8

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of HSPB8 mRNA

NCBI chr12:45,835,899...45,866,449
Ensembl chr12:40,176,532...40,191,185

G

heat shock protein family D (Hsp60) member 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of HSPD1 mRNA

NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:56,579,201...56,589,662

G

5-hydroxytryptamine receptor 1A

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of HTR1A mRNA

NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:36,694,174...36,695,442

G

5-hydroxytryptamine receptor 2A

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of HTR2A mRNA

NCBI chr15:56,360,647...56,428,703
Ensembl chr15:49,950,804...50,020,928

G

5-hydroxytryptamine receptor 2C

decreases expression

butylbenzyl phthalate results in decreased expression of HTR2C mRNA

NCBI chr X:115,453,190...115,682,325
Ensembl chr X:110,641,153...110,870,287

G

HtrA serine peptidase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of HTRA1 mRNA

NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:185,497,735...185,547,379

G

inhibitor of DNA binding 1

decreases expression

butylbenzyl phthalate results in decreased expression of ID1 mRNA

NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:141,211,267...141,212,419

G

isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of IDH3A mRNA

NCBI chr 8:63,867,882...63,887,223
Ensembl chr 8:54,971,740...54,991,084

G

indoleamine 2,3-dioxygenase 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of IDO2 mRNA

NCBI chr16:74,161,761...74,200,651
Ensembl chr16:67,459,190...67,496,324

G

immediate early response 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of IER2 mRNA

NCBI chr19:40,399,373...40,400,897
Ensembl chr19:23,494,184...23,499,211

G

interferon, alpha-inducible protein 27 like 2A

decreases expression

butylbenzyl phthalate results in decreased expression of IFI27L2A mRNA

NCBI chr 6:122,598,872...122,600,358
Ensembl chr 6:122,598,872...122,600,360

G

interferon gamma

multiple interactions
increases expression

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] affects the expression of and affects the secretion of IFNG protein
butylbenzyl phthalate results in increased expression of IFNG protein

PMID:32308655 PMID:38954831

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375

G

insulin-like growth factor 1

decreases expression

butylbenzyl phthalate results in decreased expression of IGF1 mRNA

NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor binding protein 1

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in decreased expression of IGFBP1 mRNA

NCBI chr14:86,261,277...86,266,344
Ensembl chr14:82,047,415...82,052,482

G

insulin-like growth factor binding protein 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased secretion of IGFBP2 protein

NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:74,415,546...74,442,937

G

insulin-like growth factor binding protein 5

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of IGFBP5 mRNA

NCBI chr 9:81,901,605...81,914,187
Ensembl chr 9:74,448,382...74,465,156

G

insulin-like growth factor binding protein 6

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased secretion of IGFBP6 protein

NCBI chr 7:135,154,919...135,159,550
Ensembl chr 7:133,276,234...133,280,966

G

insulin-like growth factor binding protein 7

decreases expression

butylbenzyl phthalate results in decreased expression of IGFBP7 mRNA

NCBI chr14:31,091,681...31,151,623
Ensembl chr14:30,737,164...30,797,314

G

interleukin 10

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in decreased expression of IL10 mRNA

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313

G

interleukin 11

increases expression

butylbenzyl phthalate results in increased expression of IL11 mRNA

NCBI chr 1:78,098,622...78,104,915
Ensembl chr 1:69,068,137...69,076,129

G

interleukin 12A

increases expression

butylbenzyl phthalate results in increased expression of IL12A mRNA

NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:152,965,769...152,972,734

G

interleukin 13

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in decreased expression of IL13 mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] affects the expression of and affects the secretion of IL13 protein

PMID:35739755 PMID:38954831

NCBI chr10:38,290,926...38,293,483
Ensembl chr10:37,790,130...37,792,737

G

interleukin 17A

increases expression

butylbenzyl phthalate results in increased expression of IL17A protein

NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:23,144,402...23,147,889

G

interleukin 17 receptor A

increases expression

butylbenzyl phthalate results in increased expression of IL17R mRNA

NCBI chr 4:155,339,742...155,362,382
Ensembl chr 4:153,667,534...153,690,174

G

interleukin 1 beta

multiple interactions

[butylbenzyl phthalate co-treated with COL2A1 protein] results in increased expression of IL1B protein; [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of IL1B mRNA

PMID:32308655 PMID:37021957

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 4

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in decreased expression of IL4 mRNA

NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750

G

interleukin 6

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of IL6 mRNA; [butylbenzyl phthalate co-treated with COL2A1 protein] results in increased expression of IL6 protein; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of IL6 mRNA]

PMID:32308655 PMID:33316053 PMID:35739755

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178

G

inhibin subunit alpha

decreases expression

butylbenzyl phthalate results in decreased expression of INHA mRNA

PMID:26472102 PMID:33983380

NCBI chr 9:84,443,109...84,446,010
Ensembl chr 9:76,993,589...76,997,248

G

inositol polyphosphate-5-phosphatase J

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of INPP5J mRNA

NCBI chr14:82,597,789...82,608,930
Ensembl chr14:78,374,161...78,385,326

G

insulin 1

multiple interactions

butylbenzyl phthalate promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]

NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:251,244,973...251,245,536

G

insulin 2

multiple interactions

[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] affects the abundance of diphosphoric acid analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of carbamic acid analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Cholesterol analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Cystathionine analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Desmosterol analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of ethylamine analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Glycine analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Inositol analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of methylphosphate analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of monoethyl phosphate analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of n-butylamine analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Palmitic Acid analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of phosphoric acid analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Pyrrolidonecarboxylic Acid analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of sebacic acid analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of stearic acid analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of undecane analog; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of ACACA protein; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of ADIPOQ mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of ADIPOQ protein; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of CEBPA mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of CEBPA protein; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of CFD mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of FABP4 mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of FASN mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of FASN protein; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of LPL mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of PLIN1 protein; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of PPARG mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of PPARG protein; butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased abundance of Triglycerides]; butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA]; butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA]; butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA]; butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased abundance of Triglycerides]]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA]]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA]]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA]]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of TNF mRNA]]
butylbenzyl phthalate promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]; butylbenzyl phthalate promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]; butylbenzyl phthalate promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]

PMID:26820058 PMID:28595985 PMID:31016361 PMID:34864131

NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:197,843,281...197,864,775

G

insulin induced gene 1

decreases expression
multiple interactions

butylbenzyl phthalate results in decreased expression of INSIG1 mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of INSIG1 mRNA

PMID:15728792 PMID:31240115

NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:7,315,495...7,323,952

G

insulin-like 3

decreases expression
multiple interactions

butylbenzyl phthalate results in decreased expression of INSL3 mRNA
[diisobutyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate] results in decreased expression of INSL3 mRNA

PMID:14687758 PMID:16102138 PMID:18411233 PMID:33983380 PMID:37788136

NCBI chr16:18,432,668...18,434,539
Ensembl chr16:18,384,829...18,400,560

G

integrator complex subunit 13

multiple interactions

[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate] affects the expression of INTS13 protein

NCBI chr 4:179,459,740...179,491,541
Ensembl chr 4:179,459,740...179,491,541

G

interferon regulatory factor 2 binding protein 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of IRF2BP2 mRNA

NCBI chr19:71,456,689...71,462,368
Ensembl chr19:54,560,128...54,566,642

G

immunity-related GTPase M

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of IRGM1 mRNA

NCBI chr10:33,734,640...33,742,720
Ensembl chr10:33,233,455...33,241,578

G

immunity-related GTPase Q

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of IRGQ mRNA

NCBI chr 1:80,123,925...80,131,881
Ensembl chr 1:80,123,925...80,131,881

G

insulin receptor substrate 1

decreases expression

butylbenzyl phthalate results in decreased expression of IRS1 mRNA

NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:83,548,944...83,606,122

G

ISG15 ubiquitin-like modifier

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ISG15 mRNA

NCBI chr 5:172,066,369...172,067,656
Ensembl chr 5:166,784,148...166,785,435

G

integrin subunit alpha 11

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ITGA11 mRNA

NCBI chr 8:72,041,432...72,150,137
Ensembl chr 8:63,146,001...63,254,407

G

integrin subunit alpha 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ITGA2 mRNA

NCBI chr 2:48,253,412...48,354,509
Ensembl chr 2:46,523,948...46,621,481

G

integrin subunit alpha 7

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ITGA7 mRNA

NCBI chr 7:1,944,447...1,973,347
Ensembl chr 7:1,359,940...1,388,450

G

integrin subunit beta 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ITGB3 mRNA

NCBI chr10:90,009,927...90,067,787
Ensembl chr10:89,509,989...89,564,679

G

inter-alpha-trypsin inhibitor heavy chain 5

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ITIH5 mRNA

NCBI chr17:73,161,886...73,261,930
Ensembl chr17:68,252,128...68,352,207

G

inositol 1,4,5-trisphosphate receptor interacting protein

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ITPRIP mRNA

NCBI chr 1:246,762,804...246,786,379
Ensembl chr 1:246,762,472...246,786,408

G

jagged canonical Notch ligand 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of JAG1 mRNA

NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:124,406,794...124,442,209

G

JunB proto-oncogene, AP-1 transcription factor subunit

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of JUNB mRNA

NCBI chr19:40,081,126...40,082,910
Ensembl chr19:23,176,294...23,178,035

G

KN motif and ankyrin repeat domains 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of KANK4 mRNA

NCBI chr 5:113,401,491...113,465,526
Ensembl chr 5:113,402,468...113,465,555

G

kelch repeat and BTB domain containing 11

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of KBTBD11 mRNA

NCBI chr16:74,618,291...74,638,010
Ensembl chr16:74,615,792...74,637,736

G

potassium channel tetramerization domain containing 10

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of KCTD10 mRNA

NCBI chr12:47,890,777...47,909,391
Ensembl chr12:42,230,269...42,248,783

G

potassium channel tetramerization domain containing 11

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of KCTD11 mRNA

NCBI chr10:54,602,575...54,604,738
Ensembl chr10:54,599,754...54,604,760

G

KDEL endoplasmic reticulum protein retention receptor 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of KDELR3 mRNA

NCBI chr 7:112,959,632...112,969,858
Ensembl chr 7:111,079,218...111,101,600

G

kinesin family member 18B

decreases expression

butylbenzyl phthalate results in decreased expression of KIF18B mRNA

NCBI chr10:88,370,520...88,392,388
Ensembl chr10:87,870,428...87,889,850

G

kinesin family member 5A

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of KIF5A protein; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of KIF5A mRNA

NCBI chr 7:64,937,210...64,974,339
Ensembl chr 7:63,049,424...63,092,858

G

kinesin family member 5C

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of KIF5C mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of KIF5C mRNA

PMID:31199487 PMID:39150890

NCBI chr 3:54,441,266...54,591,630
Ensembl chr 3:34,032,105...34,182,413

G

KLF transcription factor 1

decreases expression

butylbenzyl phthalate results in decreased expression of KLF1 mRNA

NCBI chr19:40,155,476...40,158,651
Ensembl chr19:23,250,631...23,253,758

G

KLF transcription factor 11

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of KLF11 mRNA

NCBI chr 6:41,285,699...41,297,548
Ensembl chr 6:41,285,842...41,297,550

G

lysine methyltransferase 5A

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of KMT5A mRNA

NCBI chr12:37,800,339...37,823,706
Ensembl chr12:32,139,178...32,162,711

G

keratin 18

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of KRT18 mRNA

NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:133,157,475...133,161,166
Ensembl chr10:133,157,475...133,161,166

G

keratin 7

decreases expression
multiple interactions

butylbenzyl phthalate results in decreased expression of KRT7 protein
HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate results in decreased expression of KRT7 protein]

NCBI chr 7:134,407,626...134,423,787
Ensembl chr 7:132,528,895...132,545,052

G

L1 cell adhesion molecule

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of L1CAM mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of L1CAM protein

PMID:31199487 PMID:37690569

NCBI chr X:156,748,597...156,775,116
Ensembl chr X:151,597,277...151,623,857

G

lysosomal-associated membrane protein 3

decreases expression

butylbenzyl phthalate results in decreased expression of LAMP3 mRNA

NCBI chr11:94,657,817...94,726,451
Ensembl chr11:81,193,649...81,221,784

G

lysosomal protein transmembrane 5

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of LAPTM5 mRNA

NCBI chr 5:148,371,880...148,393,927
Ensembl chr 5:143,087,759...143,109,807

G

large tumor suppressor kinase 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of LATS2 mRNA

NCBI chr15:35,940,632...35,992,225
Ensembl chr15:31,825,092...31,877,220

G

lipocalin 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of LCN2 mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased secretion of LCN2 protein

PMID:31199487 PMID:38954831

NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:15,680,687...15,684,095

G

low density lipoprotein receptor

decreases expression
multiple interactions

butylbenzyl phthalate results in decreased expression of LDLR mRNA
[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of LDLR mRNA

PMID:15728792 PMID:35739755

NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:20,270,041...20,294,580

G

lymphoid enhancer binding factor 1

multiple interactions

butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]]; trichostatin A inhibits the reaction [butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]]

NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:219,666,592...219,779,794

G

leptin

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased secretion of LEP protein

NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262

G

leucine-rich repeat-containing G protein-coupled receptor 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of LGR4 mRNA

NCBI chr 3:116,901,968...117,004,584
Ensembl chr 3:96,447,858...96,548,899

G

leucine-rich repeat-containing G protein-coupled receptor 6

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of LGR6 mRNA

NCBI chr13:48,976,193...49,095,870
Ensembl chr13:46,424,383...46,543,945

G

luteinizing hormone subunit beta

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased secretion of LHB protein; [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate] results in decreased secretion of LHB protein

PMID:37364641 PMID:37839492

NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972

G

luteinizing hormone/choriogonadotropin receptor

decreases expression
increases expression

butylbenzyl phthalate results in decreased expression of LHCGR mRNA
butylbenzyl phthalate results in increased expression of LHCGR mRNA; butylbenzyl phthalate results in increased expression of LHCGR protein

PMID:15728792 PMID:31319113

NCBI chr 6:11,415,361...11,480,834
Ensembl chr 6:5,661,871...5,724,521

G

lipase E, hormone sensitive type

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of LIPE mRNA

NCBI chr 1:90,093,433...90,112,117
Ensembl chr 1:80,965,627...80,984,310

G

small nucleolar RNA SNORA13

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in increased expression of SNORA13 mRNA

NCBI chr18:25,404,452...25,404,585
Ensembl chr18:25,404,452...25,404,585

G

small nucleolar RNA SNORA72

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in increased expression of SNORA72 mRNA

NCBI chr X:66,278,209...66,278,328
Ensembl chr X:66,278,209...66,278,328

G

LON peptidase N-terminal domain and ring finger 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of LONRF2 mRNA

NCBI chr 9:41,033,125...41,070,551
Ensembl chr 9:41,034,628...41,070,649

G

lysophosphatidylcholine acyltransferase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of LPCAT1 mRNA

NCBI chr 1:31,594,621...31,644,946
Ensembl chr 1:29,766,071...29,816,401

G

lipin 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of LPIN1 mRNA

NCBI chr 6:45,039,110...45,145,845
Ensembl chr 6:39,312,748...39,417,097

G

lipoprotein lipase

multiple interactions

[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of LPL mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of LPL mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of LPL mRNA

PMID:26820058 PMID:30768133 PMID:39150890

NCBI chr16:25,596,205...25,621,928
Ensembl chr16:20,829,465...20,855,249

G

LRAT domain containing 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of LRATD1 mRNA

NCBI chr 6:36,916,969...36,922,143
Ensembl chr 6:36,913,469...36,922,319

G

leucine-rich alpha-2-glycoprotein 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of LRG1 mRNA

NCBI chr 9:1,034,691...1,036,937
Ensembl chr 9:947,516...949,813

G

leucine rich repeat containing 4B

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of LRRC4B mRNA

NCBI chr 1:104,058,558...104,092,831
Ensembl chr 1:94,935,603...94,956,263

G

leucine-rich repeats and transmembrane domains 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of LRTM2 mRNA

NCBI chr 4:154,158,165...154,180,389
Ensembl chr 4:152,485,866...152,500,377

G

lanosterol synthase

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of LSS mRNA

NCBI chr20:12,090,641...12,118,230
Ensembl chr20:12,092,774...12,118,762

G

lumican

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in decreased expression of LUM mRNA

NCBI chr 7:34,245,323...34,252,510
Ensembl chr 7:32,358,614...32,365,793

G

Ly6/neurotoxin 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of LYNX1 mRNA

NCBI chr 7:108,521,783...108,527,012
Ensembl chr 7:106,632,797...106,638,023

G

MAF bZIP transcription factor K

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of MAFK mRNA

NCBI chr12:19,948,473...19,970,351
Ensembl chr12:14,833,984...14,837,048
Ensembl chr12:14,833,984...14,837,048

G

MAGE family member E1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of MAGEE1 mRNA

NCBI chr X:70,189,242...70,192,789
Ensembl chr X:70,189,187...70,192,810

G

microtubule-associated protein 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of MAP2 mRNA

NCBI chr 9:75,173,038...75,431,606
Ensembl chr 9:67,723,371...67,979,809

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microtubule-associated protein 6

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of MAP6 mRNA

NCBI chr 1:162,980,339...163,046,548
Ensembl chr 1:153,568,368...153,634,414

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mitogen activated protein kinase 1

increases phosphorylation
multiple interactions

butylbenzyl phthalate results in increased phosphorylation of MAPK1 protein
[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of MAPK1 protein; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased phosphorylation of MAPK1 protein

PMID:31319113 PMID:35739755 PMID:37364641

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 14

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of MAPK14 protein

NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,749,670...6,810,589

G

mitogen activated protein kinase 3

increases phosphorylation
multiple interactions

butylbenzyl phthalate results in increased phosphorylation of MAPK3 protein
[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of MAPK3 protein; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased phosphorylation of MAPK3 protein

PMID:31319113 PMID:35739755 PMID:37364641

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863

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microtubule-associated protein, RP/EB family, member 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of MAPRE3 mRNA

NCBI chr 6:31,233,736...31,278,626
Ensembl chr 6:25,513,800...25,558,881

G

microtubule-associated protein tau

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of MAPT mRNA

NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,138,627...89,236,129

G

microtubule affinity regulating kinase 4

multiple interactions

[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate] affects the expression of MARK4 protein

NCBI chr 1:88,203,352...88,239,858
Ensembl chr 1:79,068,904...79,108,556

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membrane bound O-acyltransferase domain containing 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of MBOAT1 mRNA

NCBI chr17:34,331,413...34,445,088
Ensembl chr17:34,331,422...34,445,088

G

membrane bound O-acyltransferase domain containing 7

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of MBOAT7 mRNA

NCBI chr 1:65,525,206...65,539,538
Ensembl chr 1:65,525,213...65,539,538

G

melanocortin 2 receptor

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of MC2R mRNA

NCBI chr18:64,279,878...64,291,775
Ensembl chr18:62,004,948...62,015,488

G

methylcrotonyl-CoA carboxylase subunit 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of MCCC1 mRNA

NCBI chr 2:118,799,147...118,851,181
Ensembl chr 2:118,799,150...118,851,222

G

minichromosome maintenance complex component 2

decreases expression

butylbenzyl phthalate results in decreased expression of MCM2 mRNA

NCBI chr 4:122,903,679...122,918,205
Ensembl chr 4:121,346,434...121,360,847

G

minichromosome maintenance complex component 5

decreases expression

butylbenzyl phthalate results in decreased expression of MCM5 mRNA

NCBI chr19:13,488,813...13,510,131
Ensembl chr19:13,483,066...13,504,389

G

minichromosome maintenance complex component 6

decreases expression

butylbenzyl phthalate results in decreased expression of MCM6 mRNA

NCBI chr13:42,379,161...42,404,352
Ensembl chr13:39,826,763...39,851,960

G

malic enzyme 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ME3 mRNA

NCBI chr 1:152,946,595...153,148,026
Ensembl chr 1:143,534,139...143,733,132

G

mex-3 RNA binding family member B

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of MEX3B mRNA

NCBI chr 1:136,855,130...136,859,365
Ensembl chr 1:136,855,130...136,859,354

G

major facilitator superfamily domain containing 4A

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of MFSD4A mRNA

NCBI chr13:43,469,488...43,510,467
Ensembl chr13:43,469,488...43,510,467

G

monoglyceride lipase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of MGLL mRNA

NCBI chr 4:122,749,436...122,851,440
Ensembl chr 4:121,192,195...121,294,179

G

microsomal glutathione S-transferase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of MGST1 mRNA

NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:171,029,630...171,044,892

G

microRNA 107

increases expression

butylbenzyl phthalate results in increased expression of MIR107 mRNA

NCBI chr 1:241,750,418...241,750,504
Ensembl chr 1:232,337,767...232,337,853

G

microRNA 126a

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR126

NCBI chr 3:29,813,150...29,813,267
Ensembl chr 3:9,415,063...9,415,180

G

microRNA 127

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR127

NCBI chr 6:134,328,454...134,328,550
Ensembl chr 6:128,546,215...128,546,311

G

microRNA 141

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of MIR141

NCBI chr 4:159,209,525...159,209,618
Ensembl chr 4:157,523,239...157,523,332

G

microRNA 143

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR143

NCBI chr18:57,371,349...57,371,453
Ensembl chr18:55,101,006...55,101,110

G

microRNA 150

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR150

NCBI chr 1:104,741,487...104,741,571
Ensembl chr 1:95,605,024...95,605,108

G

microRNA 15b

decreases expression

butylbenzyl phthalate results in decreased expression of MIR15B mRNA

NCBI chr 2:155,555,178...155,555,275
Ensembl chr 2:153,245,200...153,245,297

G

microRNA 184

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of MIR184; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of MIR184 mRNA

PMID:31199487 PMID:35762964

NCBI chr 8:90,343,134...90,343,210
Ensembl chr 8:90,343,134...90,343,210

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microRNA 193a

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR193A

NCBI chr10:65,170,306...65,170,417
Ensembl chr10:64,672,343...64,672,454

G

microRNA 19a

multiple interactions
increases expression

MIR19A mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of CDKN1A protein]; MIR19A mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of PTEN protein]; MIR19A mRNA affects the reaction [butylbenzyl phthalate results in increased expression of CCND1 protein]; MIR19A mRNA affects the reaction [butylbenzyl phthalate results in increased expression of PCNA protein]
butylbenzyl phthalate results in increased expression of MIR19A mRNA

NCBI chr15:98,588,131...98,588,212
Ensembl chr15:92,180,912...92,180,993

G

microRNA 19b-1

multiple interactions
increases expression

MIR19B1 mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of CDKN1A protein]; MIR19B1 mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of PTEN protein]; MIR19B1 mRNA affects the reaction [butylbenzyl phthalate results in increased expression of CCND1 protein]; MIR19B1 mRNA affects the reaction [butylbenzyl phthalate results in increased expression of PCNA protein]
butylbenzyl phthalate results in increased expression of MIR19B1 mRNA

NCBI chr15:98,588,433...98,588,519
Ensembl chr15:92,181,214...92,181,300

G

microRNA 200b

multiple interactions

[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with nonylphenol co-treated with octylphenol] results in increased expression of and results in increased cleavage of MIR200B

NCBI chr 5:171,931,495...171,931,589
Ensembl chr 5:166,649,272...166,649,366

G

microRNA 203-2

multiple interactions

[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with nonylphenol co-treated with octylphenol] results in decreased expression of MIR203

NCBI chr 6:131,199,542...131,199,656
Ensembl chr 6:131,199,542...131,199,656

G

microRNA 221

multiple interactions

[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with nonylphenol co-treated with octylphenol] results in decreased expression of MIR221
[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR221

PMID:33086190 PMID:33885134

NCBI chr X:6,023,182...6,023,290
Ensembl chr X:3,429,465...3,429,573

G

microRNA 25

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR25

NCBI chr12:22,156,641...22,156,724
Ensembl chr12:17,042,932...17,043,015

G

microRNA 320a

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR320A

NCBI chr15:51,926,088...51,926,169
Ensembl chr15:45,516,392...45,516,473

G

microRNA 324

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR324

NCBI chr10:55,233,363...55,233,445
Ensembl chr10:54,734,678...54,734,766

G

microRNA 328

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR328

NCBI chr19:33,184,766...33,184,849
Ensembl chr19:33,184,766...33,184,849

G

microRNA 345

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR345

NCBI chr 6:127,754,027...127,754,122
Ensembl chr 6:127,754,027...127,754,122

G

microRNA 34a

multiple interactions
increases expression
decreases expression

MIR34A mRNA inhibits the reaction [butylbenzyl phthalate results in decreased expression of CDKN1A protein]; MIR34A mRNA inhibits the reaction [butylbenzyl phthalate results in increased expression of CCND1 protein]; MIR34A mRNA inhibits the reaction [butylbenzyl phthalate results in increased expression of MYC protein]; MIR34A mRNA inhibits the reaction [butylbenzyl phthalate results in increased expression of PCNA protein]
MIR34A mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of NAMPT protein]
butylbenzyl phthalate results in increased expression of MIR34A mRNA
butylbenzyl phthalate results in decreased expression of MIR34A mRNA

PMID:30243731 PMID:34520170

NCBI chr 5:165,815,952...165,816,053
Ensembl chr 5:160,533,002...160,533,103

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microRNA 451a

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR451A

NCBI chr10:63,459,569...63,459,640
Ensembl chr10:62,961,520...62,961,591

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microRNA 503

multiple interactions

[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with nonylphenol co-treated with octylphenol] results in increased expression of and results in increased cleavage of MIR503

NCBI chr X:137,725,856...137,725,926
Ensembl chr X:132,806,303...132,806,373

G

microRNA 532

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR532

NCBI chr X:17,919,185...17,919,263
Ensembl chr X:15,247,315...15,247,393

G

microRNA 675

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in decreased expression of MIR675 mRNA

NCBI chr 1:207,161,752...207,161,835
Ensembl chr 1:197,732,275...197,732,358

G

microRNA 96

multiple interactions

[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with nonylphenol co-treated with octylphenol] results in increased expression of and results in increased cleavage of MIR96

NCBI chr 4:59,755,841...59,755,946
Ensembl chr 4:58,788,411...58,788,516

G

microRNA 99b

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR99B

NCBI chr 1:67,350,064...67,350,133
Ensembl chr 1:58,677,011...58,677,090

G

microRNA let-7a-1

increases expression

butylbenzyl phthalate results in increased expression of MIRLET7A-1 mRNA

NCBI chr17:16,320,133...16,320,226
Ensembl chr17:16,113,768...16,113,867

G

microRNA let-7b

increases expression

butylbenzyl phthalate results in increased expression of MIRLET7B mRNA

NCBI chr 7:118,684,038...118,684,122
Ensembl chr 7:116,804,186...116,804,270

G

microRNA let-7c-1

increases expression

butylbenzyl phthalate results in increased expression of MIRLET7C-1 mRNA

NCBI chr11:29,688,112...29,688,205
Ensembl chr11:16,201,158...16,201,265

G

microRNA let-7d

increases expression

butylbenzyl phthalate results in increased expression of MIRLET7D mRNA

NCBI chr17:16,322,260...16,322,357
Ensembl chr17:16,115,893...16,115,990

G

microRNA let7f-1

increases expression

butylbenzyl phthalate results in increased expression of MIRLET7F-1 mRNA

NCBI chr17:16,320,497...16,320,593
Ensembl chr17:16,114,130...16,114,226

G

MLLT11, transcription factor 7 cofactor

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of MLLT11 mRNA

NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199

G

MLX interacting protein-like

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of MLXIPL mRNA

NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112

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membrane metallo-endopeptidase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of MME mRNA

NCBI chr 2:149,806,826...149,957,381
Ensembl chr 2:147,722,086...147,803,792

G

matrix metallopeptidase 14

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] promotes the reaction [CGA protein results in increased expression of MMP14 mRNA]

NCBI chr15:31,857,824...31,867,049
Ensembl chr15:27,887,727...27,899,864

G

matrix metallopeptidase 16

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] promotes the reaction [CGA protein results in increased expression of MMP16 mRNA]

NCBI chr 5:36,109,265...36,353,252
Ensembl chr 5:31,312,280...31,548,388

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matrix metallopeptidase 2

multiple interactions
increases expression

ZEB1 protein affects the reaction [butylbenzyl phthalate results in increased expression of MMP2 protein]

NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870

G

matrix metallopeptidase 3

increases expression
multiple interactions

butylbenzyl phthalate results in increased expression of MMP3 protein
butylbenzyl phthalate promotes the reaction [ETS1 protein binds to MMP3 promoter]; butylbenzyl phthalate promotes the reaction [NR1I2 protein binds to MMP3 promoter]

NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:4,640,416...4,653,961

G

matrix metallopeptidase 9

increases expression
multiple interactions

butylbenzyl phthalate results in increased expression of MMP9 protein
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of MMP9 mRNA]

PMID:31212022 PMID:33316053 PMID:33965509

NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120

G

MAGUK p55 scaffold protein 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of MPP2 mRNA

NCBI chr10:87,011,434...87,043,883
Ensembl chr10:87,011,434...87,043,896

G

myelin protein zero-like 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of MPZL2 mRNA

NCBI chr 8:54,244,920...54,256,064
Ensembl chr 8:45,348,285...45,359,298

G

MRG domain binding protein

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of MRGBP mRNA

NCBI chr 3:188,074,695...188,078,162
Ensembl chr 3:167,697,185...167,700,592

G

mitochondrial ribosomal protein L1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of MRPL1 mRNA

NCBI chr14:13,604,498...13,663,633
Ensembl chr14:13,300,522...13,359,721

G

mitochondrial ribosomal protein L42

decreases expression

butylbenzyl phthalate results in decreased expression of MRPL42 mRNA

NCBI chr 7:32,004,863...32,028,640
Ensembl chr 7:30,117,977...30,141,639

G

mutS homolog 2

decreases expression

butylbenzyl phthalate results in decreased expression of MSH2 mRNA

NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:6,813,795...6,872,938

G

metallothionein 2

decreases expression

butylbenzyl phthalate results in decreased expression of MT2 mRNA

NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,832,002...10,832,784

G

MTSS I-BAR domain containing 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of MTSS2 mRNA

NCBI chr19:38,692,793...38,714,575
Ensembl chr19:38,693,194...38,713,507

G

microtubule associated scaffold protein 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of MTUS1 mRNA

NCBI chr16:57,905,991...58,051,466
Ensembl chr16:51,253,562...51,347,793

G

mevalonate diphosphate decarboxylase

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of MVD mRNA

NCBI chr19:67,404,911...67,414,974
Ensembl chr19:50,496,367...50,507,971

G

MYC proto-oncogene, bHLH transcription factor

multiple interactions
increases expression

MIR34A mRNA inhibits the reaction [butylbenzyl phthalate results in increased expression of MYC protein]
butylbenzyl phthalate results in increased expression of MYC mRNA; butylbenzyl phthalate results in increased expression of MYC protein

NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630

G

myosin X

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of MYO10 mRNA

NCBI chr 2:76,100,989...76,305,619
Ensembl chr 2:76,100,987...76,303,030

G

myocardin

decreases expression

butylbenzyl phthalate results in decreased expression of MYOCD mRNA

NCBI chr10:50,332,356...50,426,819
Ensembl chr10:49,836,641...49,927,627

G

Ngfi-A binding protein 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NAB2 mRNA

NCBI chr 7:65,382,863...65,389,527
Ensembl chr 7:63,497,589...63,503,989

G

NAC alpha domain containing

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NACAD mRNA

NCBI chr14:81,465,299...81,473,866
Ensembl chr14:81,465,299...81,473,781

G

nicotinamide phosphoribosyltransferase

decreases expression
multiple interactions

butylbenzyl phthalate results in decreased expression of NAMPT mRNA; butylbenzyl phthalate results in decreased expression of NAMPT protein
MIR34A mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of NAMPT protein]

NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:49,424,332...49,462,100

G

neurocalcin delta

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NCALD mRNA

NCBI chr 7:68,532,671...68,964,740
Ensembl chr 7:68,534,421...68,964,496

G

neutral cholesterol ester hydrolase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NCEH1 mRNA

NCBI chr 2:112,003,677...112,064,274
Ensembl chr 2:110,074,957...110,135,588

G

neutrophil cytosolic factor 1

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of NCF1 mRNA

NCBI chr12:28,121,816...28,131,080
Ensembl chr12:22,485,451...22,494,646

G

neuronal calcium sensor 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NCS1 mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NCS1 mRNA

PMID:31199487 PMID:39150890

NCBI chr 3:34,920,949...34,966,554
Ensembl chr 3:14,523,220...14,568,829

G

necdin, MAGE family member

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NDN mRNA

NCBI chr 1:115,849,168...115,850,767
Ensembl chr 1:115,849,105...115,850,767

G

NDRG family member 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NDRG4 mRNA

NCBI chr19:9,351,408...9,387,398
Ensembl chr19:9,351,404...9,386,914

G

Ndufa4, mitochondrial complex associated

decreases expression

butylbenzyl phthalate results in decreased expression of NDUFA4 mRNA

NCBI chr 4:40,968,391...40,975,559
Ensembl chr 4:40,002,216...40,023,920

G

NADH:ubiquinone oxidoreductase core subunit S1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NDUFS1 mRNA

NCBI chr 9:72,040,286...72,073,605
Ensembl chr 9:64,546,225...64,579,893

G

neurofilament heavy chain

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NEFH mRNA

NCBI chr14:84,044,428...84,054,413
Ensembl chr14:79,830,362...79,840,351

G

neurofilament light chain

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NEFL mRNA

NCBI chr15:46,477,330...46,481,203
Ensembl chr15:42,301,916...42,305,793

G

neural EGFL like 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NELL1 mRNA

NCBI chr 1:99,709,305...100,573,872
Ensembl chr 1:99,709,793...100,573,860

G

NFE2 like bZIP transcription factor 2

decreases expression
multiple interactions

butylbenzyl phthalate results in decreased expression of NFE2L2 mRNA
[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of NFE2L2 mRNA; [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of NFE2L2 mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NFE2L2 mRNA

PMID:27923775 PMID:37021957 PMID:37364641 PMID:39150890

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737

G

NFE2 like bZIP transcription factor 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NFE2L3 mRNA

NCBI chr 4:80,506,756...80,534,629
Ensembl chr 4:80,506,756...80,534,629

G

nuclear factor, interleukin 3 regulated

increases expression

butylbenzyl phthalate results in increased expression of NFIL3 mRNA

NCBI chr17:12,432,376...12,447,605
Ensembl chr17:12,280,484...12,295,858

G

nerve growth factor receptor

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NGFR mRNA

NCBI chr10:81,012,077...81,030,305
Ensembl chr10:80,515,299...80,533,518

G

NHERF family PDZ scaffold protein 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC9A3R1 mRNA

NCBI chr10:100,902,165...100,919,265
Ensembl chr10:100,403,069...100,420,598

G

NME/NM23 nucleoside diphosphate kinase 1

decreases expression

butylbenzyl phthalate results in decreased expression of NME1 mRNA

NCBI chr10:79,403,939...79,426,620
Ensembl chr10:78,906,083...78,916,408

G

nicotinamide riboside kinase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NMRK1 mRNA

NCBI chr 1:225,475,975...225,503,414
Ensembl chr 1:216,049,437...216,076,791

G

neuronatin

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NNAT mRNA

NCBI chr 3:166,646,373...166,648,845
Ensembl chr 3:146,226,407...146,228,834

G

nucleolar protein 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NOL4 mRNA

NCBI chr18:13,932,499...14,294,873
Ensembl chr18:13,932,510...14,296,286

G

nitric oxide synthase 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NOS2 mRNA

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210

G

notch receptor 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NOTCH4 mRNA

NCBI chr20:4,164,969...4,189,072
Ensembl chr20:4,160,445...4,184,465

G

NPC intracellular cholesterol transporter 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NPC1 mRNA

NCBI chr18:3,654,237...3,699,853
Ensembl chr18:3,379,482...3,425,049

G

N-acetylneuraminate pyruvate lyase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NPL mRNA

NCBI chr13:68,205,602...68,247,940
Ensembl chr13:65,655,118...65,697,372

G

nuclear receptor subfamily 0, group B, member 1

decreases expression

butylbenzyl phthalate results in decreased expression of NR0B1 mRNA

PMID:15728792 PMID:33983380

NCBI chr X:54,707,658...54,711,786
Ensembl chr X:50,756,886...50,761,011

G

nuclear receptor subfamily 1, group H, member 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NR1H4 mRNA

NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:23,846,122...23,942,047

G

nuclear receptor subfamily 1, group I, member 2

increases activity
multiple interactions

butylbenzyl phthalate results in increased activity of NR1I2 protein
butylbenzyl phthalate binds to and results in increased activity of NR1I2 protein
butylbenzyl phthalate binds to and results in increased activity of NR1I2 protein; butylbenzyl phthalate promotes the reaction [NR1I2 protein binds to ETS1 protein]; butylbenzyl phthalate promotes the reaction [NR1I2 protein binds to MMP3 promoter]; butylbenzyl phthalate results in increased localization of and results in increased activity of NR1I2 protein

PMID:27551952 PMID:33049310 PMID:33965509

NCBI chr11:75,965,717...76,006,733
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor subfamily 1, group I, member 3

affects binding
increases activity

butylbenzyl phthalate binds to NR1I3 protein
butylbenzyl phthalate results in increased activity of NR1I3 protein; butylbenzyl phthalate results in increased activity of NR1I3 protein alternative form

PMID:25938866 PMID:27551952 PMID:28927721

NCBI chr13:86,165,327...86,170,362
Ensembl chr13:83,632,899...83,637,906

G

nuclear receptor subfamily 3, group C, member 1

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of NR3C1 mRNA

NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375

G

nuclear receptor subfamily 3, group C, member 2

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of NR3C2 mRNA

NCBI chr19:47,619,853...47,964,089
Ensembl chr19:30,715,648...31,059,885

G

nuclear receptor subfamily 4, group A, member 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NR4A1 mRNA

NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:132,374,840...132,389,297

G

nuclear receptor subfamily 4, group A, member 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NR4A2 mRNA

NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:41,689,851...41,697,877

G

nuclear receptor subfamily 4, group A, member 3

decreases expression
multiple interactions

butylbenzyl phthalate results in decreased expression of NR4A3 mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NR4A3 mRNA

PMID:19560483 PMID:39150890

NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:62,361,822...62,402,733

G

nuclear receptor binding protein 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NRBP2 mRNA

NCBI chr 7:107,798,642...107,805,225
Ensembl chr 7:107,799,497...107,805,230

G

nuclear respiratory factor 1

decreases expression

butylbenzyl phthalate results in decreased expression of NRF1 mRNA

PMID:26520405 PMID:27923775

NCBI chr 4:59,632,366...59,738,166
Ensembl chr 4:58,664,957...58,825,328

G

neurexin 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NRXN2 mRNA

NCBI chr 1:213,155,673...213,271,526
Ensembl chr 1:203,735,753...203,842,297

G

NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL

decreases expression

butylbenzyl phthalate results in decreased expression of NSDHL mRNA

NCBI chr X:155,817,301...155,848,224
Ensembl chr X:150,775,080...150,807,142

G

neuronal vesicle trafficking associated 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NSG1 mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NSG1 mRNA

PMID:31199487 PMID:39150890

NCBI chr14:76,861,079...76,882,822
Ensembl chr14:72,648,741...72,670,514

G

neuronal vesicle trafficking associated 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of NSG2 mRNA

NCBI chr10:15,601,594...15,661,441
Ensembl chr10:15,601,596...15,661,441

G

5'-nucleotidase domain containing 2

decreases expression

butylbenzyl phthalate results in decreased expression of NT5DC2 mRNA

NCBI chr16:6,328,925...6,336,978
Ensembl chr16:6,322,236...6,330,537

G

netrin 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NTN4 mRNA

NCBI chr 7:30,073,637...30,187,407
Ensembl chr 7:28,186,611...28,300,390

G

nucleoporin 210

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NUP210 mRNA

NCBI chr 4:123,511,558...123,609,874
Ensembl chr 4:123,511,559...123,609,874

G

nuclear RNA export factor 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of NXF3 mRNA

NCBI chr X:99,025,901...99,050,409
Ensembl chr X:99,025,901...99,039,261

G

occludin

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of OCLN protein

NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:31,657,220...31,764,150

G

olfactomedin 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of OLFM1 mRNA

NCBI chr 3:11,520,522...11,558,240
Ensembl chr 3:11,520,729...11,558,239

G

olfactomedin-like 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of OLFML3 mRNA

NCBI chr 2:191,244,221...191,247,050
Ensembl chr 2:191,244,221...191,247,050

G

osteomodulin

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in decreased expression of OMD mRNA

NCBI chr17:15,266,646...15,274,870
Ensembl chr17:15,060,217...15,068,441

G

opioid related nociceptin receptor 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of OPRL1 mRNA

NCBI chr 3:189,209,495...189,225,406
Ensembl chr 3:168,834,003...168,839,920

G

oxidative stress induced growth inhibitor family member 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of OSGIN2 mRNA

NCBI chr 5:34,297,417...34,316,353
Ensembl chr 5:29,500,408...29,520,831

G

oxytocin/neurophysin I prepropeptide

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of OXT mRNA

NCBI chr 3:138,235,754...138,236,594
Ensembl chr 3:117,782,650...117,783,490

G

oxytocin receptor

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of OXTR mRNA

NCBI chr 4:147,154,374...147,171,723
Ensembl chr 4:145,599,561...145,614,674

G

prolyl 4-hydroxylase subunit alpha 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of P4HA2 mRNA

NCBI chr10:38,243,136...38,271,983
Ensembl chr10:38,243,139...38,287,314

G

palmdelphin

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PALMD mRNA

NCBI chr 2:207,574,413...207,626,239
Ensembl chr 2:204,889,533...204,941,519

G

3'-phosphoadenosine 5'-phosphosulfate synthase 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PAPSS2 mRNA

NCBI chr 1:239,867,597...239,952,614
Ensembl chr 1:230,454,426...230,539,331

G

propionyl-CoA carboxylase subunit alpha

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PCCA mRNA

NCBI chr15:106,034,586...106,374,908
Ensembl chr15:99,627,982...99,968,266

G

protocadherin gamma subfamily A, 11

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PCDHGA11 mRNA

NCBI chr18:29,583,373...29,667,865
Ensembl chr18:29,493,954...29,667,868

G

phosphoenolpyruvate carboxykinase 1

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of PCK1 mRNA

NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:161,930,256...161,936,191

G

proliferating cell nuclear antigen

multiple interactions
increases expression

MIR19A mRNA affects the reaction [butylbenzyl phthalate results in increased expression of PCNA protein]; MIR19B1 mRNA affects the reaction [butylbenzyl phthalate results in increased expression of PCNA protein]; MIR34A mRNA inhibits the reaction [butylbenzyl phthalate results in increased expression of PCNA protein]
butylbenzyl phthalate results in increased expression of PCNA mRNA; butylbenzyl phthalate results in increased expression of PCNA protein

PMID:29864457 PMID:30243731 PMID:31016752

NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:119,498,810...119,502,995

G

Purkinje cell protein 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PCP4 mRNA

NCBI chr11:49,229,185...49,331,186
Ensembl chr11:35,800,713...35,861,725

G

proprotein convertase subtilisin/kexin type 1 inhibitor

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PCSK1N mRNA

NCBI chr X:17,251,963...17,255,405
Ensembl chr X:14,580,038...14,583,566

G

proprotein convertase subtilisin/kexin type 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PCSK2 mRNA

NCBI chr 3:151,333,938...151,636,628
Ensembl chr 3:130,880,422...131,183,127

G

proprotein convertase subtilisin/kexin type 5

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PCSK5 mRNA

NCBI chr 1:224,263,823...224,694,350
Ensembl chr 1:214,837,927...215,267,600

G

proprotein convertase subtilisin/kexin type 9

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased secretion of PCSK9 protein

NCBI chr 5:126,440,102...126,462,507
Ensembl chr 5:121,211,278...121,233,688

G

phosphate cytidylyltransferase 1A, choline

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PCYT1A mRNA

NCBI chr11:68,313,860...68,357,828
Ensembl chr11:68,313,882...68,357,357

G

phosphodiesterase 1B

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PDE1B mRNA

NCBI chr 7:136,505,834...136,533,034
Ensembl chr 7:134,627,322...134,654,580

G

phosphodiesterase 3A

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PDE3A mRNA

NCBI chr 4:175,904,276...176,170,531
Ensembl chr 4:174,172,868...174,438,274

G

phosphodiesterase 3B

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PDE3B mRNA

NCBI chr 1:178,041,207...178,204,503
Ensembl chr 1:168,607,022...168,769,334

G

phosphodiesterase 4B

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PDE4B mRNA

NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:116,799,971...117,367,696

G

phosphodiesterase 4D

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PDE4D mRNA

NCBI chr 2:41,748,337...43,262,567
Ensembl chr 2:40,019,933...41,525,884

G

platelet derived growth factor subunit B

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in increased secretion of PDGFB protein

NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:111,540,345...111,557,984

G

platelet derived growth factor C

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PDGFC mRNA

NCBI chr 2:168,613,409...168,791,575
Ensembl chr 2:166,316,803...166,493,433

G

pyruvate dehydrogenase kinase 3

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of PDK3 mRNA

NCBI chr X:62,480,535...62,547,371
Ensembl chr X:58,486,554...58,553,557

G

pyruvate dehydrogenase kinase 4

increases expression
multiple interactions

butylbenzyl phthalate results in increased expression of PDK4 protein
[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of PDK4 mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of PDK4 mRNA
butylbenzyl phthalate results in increased expression of and results in increased stability of PDK4 mRNA

PMID:31629899 PMID:37364641 PMID:39150890

NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:33,589,799...33,601,850

G

pyruvate dehydrogenase phosphatase catalytic subunit 2

increases expression

butylbenzyl phthalate results in increased expression of PDP2 mRNA

NCBI chr19:392,858...400,529
Ensembl chr19:386,406...394,074

G

PDZ domain containing RING finger 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PDZRN3 mRNA

NCBI chr 4:135,327,082...135,553,294
Ensembl chr 4:133,770,736...133,996,959

G

period circadian regulator 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PER1 mRNA

NCBI chr10:54,299,002...54,313,804
Ensembl chr10:53,805,535...53,814,431

G

peroxisomal biogenesis factor 5-like

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PEX5L mRNA

NCBI chr 2:117,623,199...117,836,772
Ensembl chr 2:115,700,972...115,913,628

G

phosphofructokinase, platelet

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of PFKP mRNA

NCBI chr17:68,639,749...68,704,055
Ensembl chr17:63,729,780...63,794,018

G

profilin 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PFN2 mRNA

NCBI chr 2:144,217,100...144,222,936
Ensembl chr 2:142,067,104...142,072,938

G

phosphoglycerate mutase 1

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of PGAM1 mRNA

NCBI chr 1:250,673,152...250,680,762
Ensembl chr 1:240,723,920...240,738,452

G

progesterone receptor

increases expression
multiple interactions

butylbenzyl phthalate results in increased expression of PGR mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of PGR mRNA]; Cyclic AMP inhibits the reaction [[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of PGR mRNA]]
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of PGR mRNA]

PMID:11474214 PMID:33316053 PMID:35307500 PMID:37552060

NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:6,072,673...6,131,344

G

phosphoethanolamine/phosphocholine phosphatase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PHOSPHO1 mRNA

NCBI chr10:80,762,062...80,769,596
Ensembl chr10:80,760,792...80,770,342

G

putative homeodomain transcription factor 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PHTF1 mRNA

NCBI chr 2:194,161,343...194,249,925
Ensembl chr 2:191,473,130...191,512,078

G

phosphoinositide-3-kinase regulatory subunit 1

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of PIK3R1 protein; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of PIK3R1 protein

PMID:35739755 PMID:37364641

NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:32,882,032...32,963,631

G

PKHD1 like 1

decreases expression

butylbenzyl phthalate results in decreased expression of PKHD1L1 mRNA

NCBI chr 7:75,620,384...75,795,335
Ensembl chr 7:75,620,484...75,795,335

G

pyruvate kinase L/R

decreases expression

butylbenzyl phthalate results in decreased expression of PKLR mRNA

NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:174,543,039...174,551,870

G

placenta associated 8

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in decreased expression of PLAC8 mRNA

NCBI chr14:9,356,950...9,378,586
Ensembl chr14:9,063,048...9,074,264

G

plasminogen activator, tissue type

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of PLAT mRNA]

NCBI chr16:75,943,061...76,022,037
Ensembl chr16:69,240,585...69,268,223

G

plasminogen activator, urokinase

increases expression
multiple interactions

butylbenzyl phthalate results in increased expression of PLAU protein
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PLAU mRNA

PMID:33965509 PMID:39150890

NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,456,232...3,462,775

G

phospholipase C-like 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PLCL2 mRNA

NCBI chr 9:3,529,117...3,713,712
Ensembl chr 9:3,292,695...3,477,009

G

perilipin 1

multiple interactions
increases expression

[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of PLIN1 protein; [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of PLIN1 mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of PLIN1 mRNA
butylbenzyl phthalate results in increased expression of PLIN1 protein

PMID:26820058 PMID:34520170 PMID:37021957 PMID:39150890

NCBI chr 1:143,073,612...143,086,199
Ensembl chr 1:133,664,892...133,676,828

G

perilipin 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PLIN2 mRNA

NCBI chr 5:106,202,634...106,258,748
Ensembl chr 5:101,154,411...101,242,319

G

perilipin 5

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PLIN5 mRNA

NCBI chr 9:939,745...946,188
Ensembl chr 9:939,747...946,120

G

phospholipid phosphatase 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PLPP3 mRNA

NCBI chr 5:125,156,000...125,231,119
Ensembl chr 5:119,927,085...120,002,205

G

phospholipid phosphatase 7 (inactive)

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PLPP7 mRNA

NCBI chr 3:15,384,461...15,398,820
Ensembl chr 3:15,384,492...15,398,883

G

phospholipid phosphatase related 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PLPPR3 mRNA

NCBI chr 7:9,831,162...9,842,434
Ensembl chr 7:9,831,162...9,845,296

G

plastin 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PLS1 mRNA

NCBI chr 8:105,196,312...105,306,252
Ensembl chr 8:96,317,849...96,385,195

G

phospholipid transfer protein

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of PLTP mRNA

NCBI chr 3:173,994,162...174,011,982
Ensembl chr 3:153,574,825...153,592,647

G

plexin C1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PLXNC1 mRNA

NCBI chr 7:31,276,978...31,430,823
Ensembl chr 7:29,390,048...29,543,779

G

peroxisome proliferator activated receptor alpha

affects binding
multiple interactions

butylbenzyl phthalate binds to PPARA protein
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PPARA mRNA

PMID:23843199 PMID:28013214

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346

G

peroxisome proliferator-activated receptor delta

affects binding

butylbenzyl phthalate binds to PPARB protein

NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,298,785...6,363,968

G

peroxisome proliferator-activated receptor gamma

affects binding
increases activity
increases expression
multiple interactions

butylbenzyl phthalate binds to PPARG protein
butylbenzyl phthalate results in increased activity of PPARG protein
butylbenzyl phthalate results in increased expression of PPARG mRNA
[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of PPARG mRNA; [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of PPARG protein; butylbenzyl phthalate binds to and results in increased activity of PPARG protein; butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA]]; PPARG protein promotes the reaction [butylbenzyl phthalate binds to and results in increased activity of PPARG protein]
butylbenzyl phthalate binds to and results in increased activity of PPARG protein; butylbenzyl phthalate inhibits the reaction [GW 1929 binds to PPARG protein]

PMID:23843199 PMID:24155963 PMID:26172262 PMID:26820058 PMID:27923775 More...

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468

G

PPARG coactivator 1 alpha

decreases expression
multiple interactions
affects expression

butylbenzyl phthalate results in decreased expression of PPARGC1A mRNA
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased expression of PPARGC1A mRNA
butylbenzyl phthalate affects the expression of PPARGC1A mRNA

PMID:26520405 PMID:27923775 PMID:37021957

NCBI chr14:63,073,505...63,729,215
Ensembl chr14:58,861,144...59,512,656

G

protein phosphatase 2, regulatory subunit B, beta

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PPP2R2B mRNA

NCBI chr18:34,904,686...35,357,299
Ensembl chr18:34,653,721...35,081,025

G

PR/SET domain 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PRDM1 mRNA

NCBI chr20:49,542,465...49,564,088
Ensembl chr20:47,959,858...47,981,488

G

proteoglycan 4

increases expression

butylbenzyl phthalate results in increased expression of PRG4 mRNA

NCBI chr13:65,037,363...65,054,764
Ensembl chr13:62,487,257...62,504,119

G

proline rich membrane anchor 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PRIMA1 mRNA

NCBI chr 6:128,094,686...128,155,592
Ensembl chr 6:122,338,370...122,389,921

G

protein kinase cAMP-dependent type II regulatory subunit beta

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PRKAR2B mRNA

NCBI chr 6:54,291,143...54,381,639
Ensembl chr 6:48,563,662...48,653,933

G

protein kinase D1

multiple interactions

[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate] affects the expression of PRKD1 protein

NCBI chr 6:73,460,640...73,774,433
Ensembl chr 6:67,725,905...68,039,042

G

protein C receptor

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PROCR mRNA

NCBI chr 3:144,254,596...144,258,863
Ensembl chr 3:144,254,380...144,258,903

G

pre-mRNA processing factor 8

multiple interactions

[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate] affects the expression of PRPF8 protein

NCBI chr10:60,829,778...60,852,887
Ensembl chr10:60,331,494...60,354,606

G

peripherin

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PRPH mRNA

NCBI chr 7:132,096,888...132,101,070
Ensembl chr 7:130,218,357...130,222,136

G

serine protease 23

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PRSS23 mRNA

NCBI chr 1:152,815,301...152,835,005
Ensembl chr 1:143,401,396...143,422,091

G

peroxiredoxin like 2A

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PRXL2A mRNA

NCBI chr16:16,900,697...16,920,521
Ensembl chr16:16,866,603...16,886,433

G

phosphatase and tensin homolog

decreases expression
multiple interactions

butylbenzyl phthalate results in decreased expression of PTEN mRNA; butylbenzyl phthalate results in decreased expression of PTEN protein
MIR19A mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of PTEN protein]; MIR19B1 mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of PTEN protein]

NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838

G

prostaglandin E receptor 1

decreases expression

butylbenzyl phthalate results in decreased expression of PTGER1 mRNA

NCBI chr19:41,374,983...41,379,593
Ensembl chr19:24,467,532...24,473,559

G

prostaglandin E receptor 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PTGER2 mRNA

NCBI chr15:20,694,765...20,708,475
Ensembl chr15:18,217,285...18,228,714

G

prostaglandin E synthase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PTGES mRNA

NCBI chr 3:34,575,643...34,586,987

G

prostaglandin reductase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PTGR1 mRNA

NCBI chr 5:78,579,060...78,597,671
Ensembl chr 5:73,784,009...73,802,666

G

prostaglandin-endoperoxide synthase 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of PTGS2 mRNA]; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PTGS2 mRNA

PMID:33316053 PMID:39150890

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188

G

protein tyrosine kinase 2

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of PTK2 protein

NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:105,126,728...105,331,783

G

protein tyrosine phosphatase, non-receptor type 5

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PTPN5 mRNA

NCBI chr 1:106,756,896...106,817,369
Ensembl chr 1:97,620,642...97,679,882

G

protein tyrosine phosphatase, receptor type, N

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PTPRN mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of PTPRN mRNA

PMID:31199487 PMID:39150890

NCBI chr 9:76,741,010...76,756,704
Ensembl chr 9:76,741,016...76,756,190

G

pentraxin 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the reaction [CGA protein results in increased expression of PTX3 mRNA]
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased secretion of PTX3 protein

PMID:37552060 PMID:38954831

NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323

G

quiescin sulfhydryl oxidase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of QSOX1 mRNA

NCBI chr13:67,949,780...67,987,434
Ensembl chr13:67,949,780...67,987,459

G

RAB3B, member RAS oncogene family

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB3B mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB3B protein

PMID:31199487 PMID:37690569

NCBI chr 5:128,859,034...128,926,087
Ensembl chr 5:123,644,423...123,697,401

G

RAB6B, member RAS oncogene family

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB6B mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RAB6B protein

PMID:31199487 PMID:37690569

NCBI chr 8:112,574,223...112,642,911
Ensembl chr 8:103,695,631...103,805,732

G

ral guanine nucleotide dissociation stimulator

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of RALGDS mRNA

NCBI chr 3:11,839,686...11,880,059
Ensembl chr 3:11,839,416...11,880,059

G

receptor activity modifying protein 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of RAMP1 mRNA

NCBI chr 9:99,213,031...99,263,696
Ensembl chr 9:91,781,285...91,816,151

G

retinoic acid receptor, gamma

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of RARG mRNA

NCBI chr 7:135,246,427...135,268,889
Ensembl chr 7:133,367,833...133,390,177

G

retinoic acid receptor responder 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased secretion of RARRES2 protein

NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:77,522,535...77,525,556

G

RasGEF domain family, member 1B

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of RASGEF1B mRNA

NCBI chr14:10,164,366...10,684,184
Ensembl chr14:9,860,247...10,379,741

G

RAS-like family 11 member B

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of RASL11B mRNA

NCBI chr14:34,369,029...34,373,250
Ensembl chr14:34,014,509...34,019,152

G

Ras association domain family member 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RASSF4 mRNA

NCBI chr 4:149,897,525...149,932,658
Ensembl chr 4:149,897,543...149,932,411

G

retinol binding protein 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased secretion of RBP4 protein

NCBI chr 1:245,306,349...245,313,551
Ensembl chr 1:235,893,917...235,901,399

G

RNA binding protein, mRNA processing factor

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of RBPMS mRNA

NCBI chr16:64,942,159...65,098,504
Ensembl chr16:58,239,474...58,395,426

G

regulator of calcineurin 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of RCAN2 mRNA

NCBI chr 9:24,456,861...24,674,234
Ensembl chr 9:16,959,480...17,174,856

G

regulated endocrine-specific protein 18

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RESP18 mRNA

NCBI chr 9:76,765,179...76,771,824
Ensembl chr 9:76,764,590...76,778,722

G

retinol saturase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of RETSAT mRNA

NCBI chr 4:106,211,459...106,220,222
Ensembl chr 4:104,653,155...104,668,310

G

regulator of G-protein signaling 1

increases expression

butylbenzyl phthalate results in increased expression of RGS1 mRNA

NCBI chr13:58,568,844...58,573,187
Ensembl chr13:56,018,554...56,022,984

G

regulator of G-protein signaling 16

increases expression

butylbenzyl phthalate results in increased expression of RGS16 mRNA

NCBI chr13:68,421,480...68,443,312
Ensembl chr13:65,887,530...65,892,857

G

regulator of G-protein signaling 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of RGS2 mRNA]
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of RGS2 mRNA

PMID:37552060 PMID:39150890

NCBI chr13:58,350,063...58,352,666
Ensembl chr13:55,798,829...55,802,385

G

regulator of G-protein signaling 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of RGS4 mRNA

NCBI chr13:84,469,593...84,475,884
Ensembl chr13:81,936,775...81,943,068

G

ring finger protein 125

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of RNF125 mRNA

NCBI chr18:12,528,995...12,550,646
Ensembl chr18:12,253,852...12,275,983

G

ring finger protein 145

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of RNF145 mRNA

NCBI chr10:29,006,391...29,050,788
Ensembl chr10:29,011,548...29,050,781

G

ring finger protein 183

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of RNF183 mRNA

NCBI chr 5:80,892,683...80,914,037
Ensembl chr 5:75,876,003...75,886,191

G

RNA binding protein with serine rich domain 1

multiple interactions

[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate] affects the expression of RNPS1 protein

NCBI chr10:13,950,151...13,960,396
Ensembl chr10:13,445,653...13,455,858

G

ribosomal protein S2

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in increased expression of RPS2 mRNA

NCBI chr10:14,251,841...14,253,697
Ensembl chr10:13,747,301...13,749,163

G

RAS related 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of RRAS2 mRNA

NCBI chr 1:177,668,143...177,737,551
Ensembl chr 1:168,233,693...168,303,111

G

ribonucleotide reductase regulatory subunit M2

decreases expression

butylbenzyl phthalate results in decreased expression of RRM2 mRNA

NCBI chr 6:47,044,755...47,075,370
Ensembl chr 6:41,340,557...41,346,773

G

reticulon 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RTN1 mRNA

NCBI chr 6:90,763,212...90,983,436
Ensembl chr 6:90,763,216...90,983,436

G

reticulon 4 receptor

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of RTN4R mRNA

NCBI chr11:96,348,613...96,373,554
Ensembl chr11:82,844,309...82,869,466

G

retinoid X receptor alpha

affects binding

butylbenzyl phthalate binds to RXRA protein

NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:10,989,832...11,073,712

G

retinoid X receptor beta

affects binding

butylbenzyl phthalate binds to RXRB protein

NCBI chr20:4,818,707...4,824,968
Ensembl chr20:4,816,815...4,828,773

G

retinoid X receptor gamma

affects binding

butylbenzyl phthalate binds to RXRG protein

NCBI chr13:82,276,330...82,318,097
Ensembl chr13:79,743,563...79,785,167

G

S100 calcium binding protein A6

decreases expression

butylbenzyl phthalate results in decreased expression of S100A6 mRNA

NCBI chr 2:178,398,189...178,399,763
Ensembl chr 2:176,100,899...176,102,180

G

sterile alpha motif domain containing 4B

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SAMD4B mRNA

NCBI chr 1:83,689,413...83,728,652
Ensembl chr 1:83,689,413...83,713,853

G

scavenger receptor class A, member 5

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SCARA5 mRNA

NCBI chr15:44,055,576...44,160,593
Ensembl chr15:39,880,035...39,983,373

G

scavenger receptor class B, member 1

decreases expression
multiple interactions

butylbenzyl phthalate results in decreased expression of SCARB1 mRNA; butylbenzyl phthalate results in decreased expression of SCARB1 protein
[dimethyl phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate] results in increased expression of SCARB1 mRNA

PMID:26472102 PMID:31319113 PMID:33983380 PMID:35739735

NCBI chr12:36,957,302...37,023,982
Ensembl chr12:31,296,156...31,362,647

G

stearoyl-CoA desaturase

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of SCD1 mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of SCD mRNA

PMID:31240115 PMID:35739755

NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:243,269,747...243,282,562

G

stearoyl-coenzyme A desaturase 3

decreases expression

butylbenzyl phthalate results in decreased expression of SCD3 mRNA

NCBI chr 1:253,028,053...253,063,662
Ensembl chr 1:243,078,774...243,114,229

G

stearoyl-coenzyme A desaturase 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SCD4 mRNA

NCBI chr 1:253,152,519...253,165,216
Ensembl chr 1:243,203,881...243,215,148

G

secretogranin III

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SCG3 mRNA

NCBI chr 8:85,280,253...85,322,484
Ensembl chr 8:76,399,777...76,442,015

G

secretogranin V

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SCG5 mRNA

NCBI chr 3:120,998,420...121,042,881
Ensembl chr 3:100,544,099...100,588,463

G

secretagogin, EF-hand calcium binding protein

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in increased expression of SCGN mRNA

NCBI chr17:41,106,681...41,148,656
Ensembl chr17:41,106,467...41,148,667

G

sodium voltage-gated channel beta subunit 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SCN3B mRNA

NCBI chr 8:49,527,529...49,550,019
Ensembl chr 8:40,630,455...40,652,868

G

secernin 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SCRN1 mRNA

NCBI chr 4:84,962,450...85,024,577
Ensembl chr 4:83,632,131...83,693,852

G

selenoprotein P

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SELENOP mRNA

NCBI chr 2:54,225,736...54,236,022
Ensembl chr 2:52,498,339...52,508,852

G

semaphorin 7A (John Milton Hagen blood group)

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SEMA7A mRNA

NCBI chr 8:67,244,318...67,267,060
Ensembl chr 8:58,348,448...58,370,536

G

serpin family B member 1A

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SERPINB1A mRNA

NCBI chr17:31,799,446...31,807,853
Ensembl chr17:31,590,677...31,599,102

G

serpin family B member 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of SERPINB2 mRNA]

NCBI chr13:24,051,933...24,065,032
Ensembl chr13:23,541,400...23,550,408

G

serpin family E member 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of SERPINE1 mRNA]

NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657

G

serpin family F member 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased secretion of SERPINF1 protein; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SERPINF1 mRNA

PMID:38954831 PMID:39150890

NCBI chr10:60,748,504...60,760,898
Ensembl chr10:60,249,708...60,262,646

G

splicing factor 3b, subunit 1

multiple interactions

[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate] affects the expression of SF3B1 protein

NCBI chr 9:63,986,829...64,026,723
Ensembl chr 9:56,492,403...56,532,300

G

secreted frizzled-related protein 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SFRP1 mRNA

NCBI chr16:75,278,325...75,316,736
Ensembl chr16:68,575,763...68,614,286

G

secreted frizzled-related protein 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SFRP2 mRNA

NCBI chr 2:171,387,536...171,395,081
Ensembl chr 2:169,089,517...169,097,063

G

SH3-domain binding protein 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SH3BP4 mRNA

NCBI chr 9:89,660,156...89,739,163
Ensembl chr 9:89,660,156...89,739,163

G

SH3-domain binding protein 5

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SH3BP5 mRNA

NCBI chr16:6,589,877...6,676,524
Ensembl chr16:6,583,465...6,698,975

G

SH3 binding domain protein 5 like

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SH3BP5L mRNA

NCBI chr10:42,512,437...42,529,564
Ensembl chr10:42,512,552...42,530,221

G

SH3 domain containing GRB2 like 3, endophilin A3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SH3GL3 mRNA

NCBI chr 1:145,533,728...145,664,881
Ensembl chr 1:136,124,499...136,255,584

G

SH3 domain and tetratricopeptide repeats 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SH3TC2 mRNA

NCBI chr18:57,686,701...57,747,735
Ensembl chr18:55,416,413...55,483,083

G

sex hormone binding globulin

affects binding

butylbenzyl phthalate binds to SHBG protein

NCBI chr10:54,831,716...54,849,162
Ensembl chr10:54,332,941...54,351,057

G

SHC adaptor protein 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SHC2 mRNA

NCBI chr 7:10,717,320...10,739,539
Ensembl chr 7:10,066,705...10,088,926

G

salt-inducible kinase 1

multiple interactions
increases expression

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SIK1 mRNA
butylbenzyl phthalate results in increased expression of SIK1 mRNA

PMID:32308655 PMID:39150890

NCBI chr20:9,947,104...9,958,729
Ensembl chr20:9,947,396...9,958,991

G

sirtuin 1

decreases expression

butylbenzyl phthalate results in decreased expression of SIRT1 mRNA; butylbenzyl phthalate results in decreased expression of SIRT1 protein

PMID:26520405 PMID:27923775 PMID:34520170

NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260

G

sirtuin 3

decreases expression

butylbenzyl phthalate results in decreased expression of SIRT3 mRNA; butylbenzyl phthalate results in decreased expression of SIRT3 protein

PMID:26520405 PMID:27923775 PMID:34520170

NCBI chr 1:205,371,703...205,394,145
Ensembl chr 1:195,942,073...195,964,808

G

sirtuin 7

decreases expression
affects expression

butylbenzyl phthalate results in decreased expression of SIRT7 mRNA
butylbenzyl phthalate affects the expression of SIRT7 mRNA

PMID:27923775 PMID:31016965

NCBI chr10:106,394,802...106,401,627
Ensembl chr10:105,896,476...105,903,172

G

SIX homeobox 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SIX4 mRNA

NCBI chr 6:97,538,202...97,551,872
Ensembl chr 6:91,802,329...91,815,992

G

SLAIN motif family, member 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLAIN1 mRNA

NCBI chr15:86,897,476...86,957,113
Ensembl chr15:80,482,367...80,542,350

G

solute carrier family 12 member 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC12A2 mRNA

NCBI chr18:53,546,263...53,614,478
Ensembl chr18:51,348,302...51,416,440

G

solute carrier family 12 member 7

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC12A7 mRNA

NCBI chr 1:31,301,243...31,382,825
Ensembl chr 1:29,472,692...29,554,302

G

solute carrier family 13 member 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SLC13A2 mRNA

NCBI chr10:63,789,874...63,817,441
Ensembl chr10:63,291,815...63,319,127

G

solute carrier family 13 member 5

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC13A5 mRNA

NCBI chr10:57,364,806...57,389,500
Ensembl chr10:56,866,249...56,890,945

G

solute carrier family 16 member 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC16A3 mRNA

NCBI chr10:106,712,328...106,756,168
Ensembl chr10:106,212,778...106,222,562

G

solute carrier family 16, member 6

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC16A6 mRNA

NCBI chr10:94,923,888...94,946,990
Ensembl chr10:94,426,244...94,448,779

G

solute carrier family 1 member 5

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of SLC1A5 mRNA

NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:77,456,694...77,470,952

G

solute carrier family 1 member 6

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC1A6 mRNA

NCBI chr 7:11,492,422...11,521,007
Ensembl chr 7:10,841,837...10,870,449

G

solute carrier family 20 member 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC20A1 mRNA

NCBI chr 3:136,880,360...136,894,255
Ensembl chr 3:116,427,098...116,441,051

G

solute carrier family 24 member 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC24A3 mRNA

NCBI chr 3:153,005,418...153,504,497
Ensembl chr 3:132,551,595...133,051,192

G

solute carrier family 25 member 15

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC25A15 mRNA

NCBI chr16:76,334,037...76,357,325
Ensembl chr16:69,634,414...69,653,010

G

solute carrier family 25, member 51

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC25A51 mRNA

NCBI chr 5:59,649,980...59,663,454
Ensembl chr 5:59,649,744...59,663,581

G

solute carrier family 27 member 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC27A1 mRNA

NCBI chr16:18,311,859...18,337,024
Ensembl chr16:18,278,984...18,296,063

G

solute carrier family 27 member 6

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC27A6 mRNA

NCBI chr18:54,238,697...54,297,595
Ensembl chr18:52,041,074...52,099,414

G

solute carrier family 29 member 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SLC29A4 mRNA

NCBI chr12:16,967,047...16,998,276
Ensembl chr12:11,853,540...11,874,834

G

solute carrier family 2 member 1

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of SLC2A1 mRNA

NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:132,717,196...132,745,416

G

solute carrier family 2 member 2

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of SLC2A2 mRNA

NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:111,611,774...111,639,933

G

solute carrier family 2 member 3

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of SLC2A3 protein

NCBI chr 4:157,632,887...157,698,034
Ensembl chr 4:155,960,946...156,025,472

G

solute carrier family 36 member 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC36A2 mRNA

NCBI chr10:39,778,667...39,806,781
Ensembl chr10:39,278,046...39,306,082

G

solute carrier family 38, member 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC38A3 mRNA

NCBI chr 8:117,202,534...117,220,310
Ensembl chr 8:108,323,894...108,339,988

G

solute carrier family 38, member 5

multiple interactions
decreases expression

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC38A5 mRNA
butylbenzyl phthalate results in decreased expression of SLC38A5 mRNA

PMID:32308655 PMID:39150890

NCBI chr X:14,213,727...14,222,498
Ensembl chr X:14,213,729...14,222,498

G

solute carrier family 5 member 5

increases expression

butylbenzyl phthalate results in increased expression of SLC5A5 mRNA

NCBI chr16:18,580,705...18,590,692
Ensembl chr16:18,546,709...18,556,697

G

solute carrier family 5 member 7

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SLC5A7 mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC5A7 mRNA

PMID:31199487 PMID:39150890

NCBI chr 9:7,922,693...7,953,509
Ensembl chr 9:7,595,444...7,626,258

G

solute carrier family 6 member 7

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC6A7 mRNA

NCBI chr18:54,448,464...54,467,319
Ensembl chr18:54,448,464...54,467,319

G

solute carrier family 7 member 7

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC7A7 mRNA

NCBI chr15:31,792,122...31,852,732
Ensembl chr15:27,822,091...27,865,648

G

solute carrier family 7 member 8

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC7A8 mRNA

NCBI chr15:32,153,016...32,212,715
Ensembl chr15:28,183,015...28,242,717

G

solute carrier family 8 member A1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLC8A1 mRNA

NCBI chr 6:18,975,498...19,299,704
Ensembl chr 6:13,194,662...13,535,628

G

solute carrier organic anion transporter family, member 2a1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] promotes the reaction [CGA protein results in increased expression of SLCO2A1 mRNA]

NCBI chr 8:103,588,916...103,672,546
Ensembl chr 8:103,588,916...103,672,546

G

schlafen family member 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLFN2 mRNA

NCBI chr10:67,953,322...67,959,659
Ensembl chr10:67,953,171...67,959,458

G

SRA stem-loop interacting RNA binding protein

decreases expression

butylbenzyl phthalate results in decreased expression of SLIRP mRNA

NCBI chr 6:107,088,760...107,097,791
Ensembl chr 6:107,088,403...107,097,791

G

slit guidance ligand 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SLIT3 mRNA

NCBI chr10:20,075,929...20,660,704
Ensembl chr10:19,571,684...20,156,634

G

SMAD family member 7

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SMAD7 mRNA

NCBI chr18:71,263,508...71,291,849
Ensembl chr18:68,988,429...69,016,765

G

small integral membrane protein 24

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SMIM24 mRNA

NCBI chr 7:8,313,369...8,316,498

G

sphingomyelin phosphodiesterase 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SMPD3 mRNA

NCBI chr19:51,072,209...51,155,639
Ensembl chr19:34,162,341...34,245,749

G

small nucleolar RNA host gene 11

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SNHG11 mRNA

NCBI chr 3:147,031,367...147,037,043

G

stannin

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SNN mRNA

NCBI chr10:4,572,933...4,581,606
Ensembl chr10:4,572,376...4,584,021
Ensembl chr 1:4,572,376...4,584,021

G

small nucleolar RNA, H/ACA box 50C

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in increased expression of SNORA50C mRNA

NCBI chr10:91,435,570...91,435,702
Ensembl chr10:91,435,570...91,435,702

G

small nucleolar RNA, H/ACA box 64

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in increased expression of SNORA64 mRNA

NCBI chr10:13,748,139...13,748,272
Ensembl chr10:13,748,139...13,748,272

G

small nucleolar RNA, H/ACA box 65

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in increased expression of SNORA65 mRNA

NCBI chr 3:16,265,801...16,265,930
Ensembl chr 3:16,265,801...16,265,930

G

syntrophin, beta 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SNTB1 mRNA

NCBI chr 7:88,950,642...89,219,017
Ensembl chr 7:87,060,926...87,329,315

G

sterol O-acyltransferase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SOAT1 mRNA

NCBI chr13:71,105,178...71,147,776
Ensembl chr13:68,552,317...68,597,494

G

suppressor of cytokine signaling 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SOCS3 mRNA

NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,193,537...103,197,787

G

superoxide dismutase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SOD1 mRNA

NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249

G

spermatogenesis and oogenesis specific basic helix-loop-helix 2

increases expression
decreases expression
multiple interactions

butylbenzyl phthalate results in increased expression of SOHLH2 mRNA
butylbenzyl phthalate results in decreased expression of SOHLH2 protein
4-vinyl-1-cyclohexene dioxide inhibits the reaction [butylbenzyl phthalate results in increased expression of SOHLH2 mRNA]; [4-vinyl-1-cyclohexene dioxide co-treated with butylbenzyl phthalate] results in decreased expression of SOHLH2 protein

NCBI chr 2:139,362,246...139,384,700
Ensembl chr 2:139,362,246...139,384,699

G

sorbitol dehydrogenase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SORD mRNA

NCBI chr 3:129,638,282...129,669,727
Ensembl chr 3:109,184,676...109,216,133

G

SRY-box transcription factor 9

decreases expression
multiple interactions
increases expression

butylbenzyl phthalate results in decreased expression of SOX9 mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SOX9 mRNA
butylbenzyl phthalate results in increased expression of SOX9 mRNA; butylbenzyl phthalate results in increased expression of SOX9 protein

PMID:26472102 PMID:31319113 PMID:39150890

NCBI chr10:98,305,744...98,311,250
Ensembl chr10:97,806,485...97,811,994

G

Sp1 transcription factor

decreases expression
multiple interactions

butylbenzyl phthalate results in decreased expression of SP1 mRNA
[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of SP1 mRNA

NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:133,541,491...133,571,961

G

spermatogenesis associated 13

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SPATA13 mRNA

NCBI chr15:34,778,479...34,907,645
Ensembl chr15:34,778,473...34,905,114

G

sperm antigen with calponin homology and coiled-coil domains 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SPECC1 mRNA

NCBI chr10:47,138,351...47,412,311
Ensembl chr10:46,638,809...46,912,802

G

secreted phosphoprotein 2

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in decreased expression of SPP2 mRNA

NCBI chr 9:89,006,858...89,026,676
Ensembl chr 9:89,007,175...89,026,688

G

squalene epoxidase

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of SQLE mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SQLE mRNA

PMID:35739755 PMID:39150890

NCBI chr 7:92,758,175...92,773,049
Ensembl chr 7:90,868,011...90,883,618

G

SRC proto-oncogene, non-receptor tyrosine kinase

multiple interactions
increases phosphorylation

fulvestrant inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of SRC protein]

NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476

G

steroid 5 alpha-reductase 1

decreases expression

butylbenzyl phthalate results in decreased expression of SRD5A1 mRNA

NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:33,686,391...33,720,461

G

sterol regulatory element binding transcription factor 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of and affects the methylation of SREBF1 mRNA
[butylbenzyl phthalate co-treated with Dietary Fats] results in increased activity of and results in increased localization of SREBF1 protein

PMID:31240115 PMID:32905190

NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650

G

sterol regulatory element binding transcription factor 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of and results in increased methylation of SREBF2 mRNA

NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:113,663,202...113,720,848

G

sushi-repeat-containing protein, X-linked 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SRPX2 mRNA

NCBI chr X:101,399,748...101,425,486
Ensembl chr X:97,106,561...97,132,195

G

steroidogenic acute regulatory protein

decreases expression
multiple interactions
increases expression

butylbenzyl phthalate results in decreased expression of STAR mRNA; butylbenzyl phthalate results in decreased expression of STAR protein
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of STAR mRNA]
butylbenzyl phthalate results in increased expression of STAR mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of STAR mRNA; [diisobutyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate] results in decreased expression of STAR mRNA
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate] results in increased expression of STAR mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of STAR mRNA; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in increased expression of STAR mRNA; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diethyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased expression of STAR mRNA; [Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate] results in decreased expression of STAR mRNA; [dimethyl phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate] results in decreased expression of STAR mRNA

PMID:19560483 PMID:26472102 PMID:28013214 PMID:29029336 PMID:30802670 More...

NCBI chr16:72,969,824...72,974,447
Ensembl chr16:66,264,807...66,271,672

G

serine/threonine kinase 32C

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of STK32C mRNA

NCBI chr 1:193,900,718...193,981,723
Ensembl chr 1:193,900,718...193,981,723

G

stathmin 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of STMN4 mRNA

NCBI chr15:40,541,305...40,559,253
Ensembl chr15:40,541,357...40,559,253

G

stonin 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of STON2 mRNA

NCBI chr 6:116,291,898...116,441,391
Ensembl chr 6:110,567,485...110,676,376

G

succinate-CoA ligase GDP-forming subunit beta

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SUCLG2 mRNA

NCBI chr 4:129,623,833...129,893,937
Ensembl chr 4:128,067,033...128,337,170

G

sulfatase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SULF1 mRNA

NCBI chr 5:11,145,950...11,308,622
Ensembl chr 5:6,362,911...6,525,584

G

sushi domain containing 2

multiple interactions

[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate co-treated with lead nitrate co-treated with Mercury] results in decreased expression of SUSD2 mRNA

NCBI chr20:13,016,960...13,024,264
Ensembl chr20:13,017,477...13,024,903

G

synaptotagmin 11

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SYT11 mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of SYT11 mRNA

PMID:31199487 PMID:39150890

NCBI chr 2:176,503,845...176,530,354
Ensembl chr 2:174,206,191...174,231,964

G

synaptotagmin 5

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of SYT5 mRNA

NCBI chr 1:78,320,034...78,327,750
Ensembl chr 1:69,277,351...69,285,067

G

TBL1X/Y related 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TBL1XR1 mRNA

NCBI chr 2:106,718,811...106,857,989
Ensembl chr 2:104,801,721...104,929,055

G

T-box transcription factor 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TBX2 mRNA

NCBI chr10:71,177,082...71,186,275
Ensembl chr10:70,679,518...70,688,529

G

transcription factor 21

increases expression
decreases expression

butylbenzyl phthalate results in increased expression of TCF21 mRNA
butylbenzyl phthalate results in decreased expression of TCF21 mRNA

NCBI chr 1:24,520,499...24,523,358
Ensembl chr 1:22,701,353...22,704,202

G

transcription factor 23

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TCF23 mRNA

NCBI chr 6:25,397,889...25,406,639
Ensembl chr 6:25,397,937...25,405,880

G

transcription factor 4

multiple interactions

butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]]; trichostatin A inhibits the reaction [butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]]

NCBI chr18:65,216,840...65,563,186
Ensembl chr18:62,943,782...63,284,425

G

trichohyalin-like 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TCHHL1 mRNA

NCBI chr 2:179,134,941...179,138,467
Ensembl chr 2:179,135,796...179,138,202

G

t-complex 11 family, X-linked 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TCP11X2 mRNA

NCBI chr X:98,591,191...98,640,800
Ensembl chr X:98,591,189...98,640,763

G

t-complex-associated testis expressed 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TCTE1 mRNA

NCBI chr 9:15,463,573...15,482,258
Ensembl chr 9:15,463,739...15,472,954

G

testis development related protein

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TDRP mRNA

NCBI chr16:75,624,047...75,652,635
Ensembl chr16:75,624,907...75,652,420

G

transcription factor A, mitochondrial

decreases expression

butylbenzyl phthalate results in decreased expression of TFAM mRNA

NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,356,197...17,368,292

G

transcription factor AP-2 alpha

affects localization
multiple interactions

butylbenzyl phthalate affects the localization of TFAP2A protein
[butylbenzyl phthalate promotes the reaction [TFAP2A protein binds to HDAC6 promoter]] which results in increased expression of HDAC6 mRNA; butylbenzyl phthalate promotes the reaction [TFAP2A protein binds to HDAC6 promoter]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [butylbenzyl phthalate affects the localization of TFAP2A protein]; RTKI cpd inhibits the reaction [butylbenzyl phthalate affects the localization of TFAP2A protein]; TFAP2A mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of HDAC6 protein]

NCBI chr17:24,230,064...24,253,219
Ensembl chr17:24,024,432...24,047,507

G

trefoil factor 1

increases expression

butylbenzyl phthalate results in increased expression of TFF1 mRNA

NCBI chr20:9,237,095...9,240,956
Ensembl chr20:9,235,736...9,239,597

G

transferrin receptor

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TFRC mRNA

NCBI chr11:81,668,478...81,690,318
Ensembl chr11:68,163,413...68,185,257

G

transforming growth factor alpha

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TGFA mRNA

NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:118,618,269...118,700,894

G

transforming growth factor, beta 1

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in decreased expression of TGFB1 mRNA

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847

G

transglutaminase 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TGM2 mRNA

NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:146,772,687...146,801,981

G

thrombospondin 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of THBS3 mRNA

NCBI chr 2:174,621,788...174,633,594
Ensembl chr 2:174,621,812...174,633,594

G

thrombospondin 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of THBS4 mRNA

NCBI chr 2:25,718,219...25,760,345
Ensembl chr 2:23,983,158...24,026,313

G

thrombospondin type 1 domain containing 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of THSD4 mRNA

NCBI chr 8:60,384,636...60,984,419
Ensembl chr 8:60,386,875...61,024,995

G

thrombospondin type 1 domain containing 7B

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of THSD7B mRNA

NCBI chr13:40,768,567...41,667,262
Ensembl chr13:40,768,570...41,666,501

G

Thy-1 cell surface antigen

increases expression

butylbenzyl phthalate results in increased expression of THY1 protein

NCBI chr 8:53,286,396...53,291,541
Ensembl chr 8:44,389,513...44,394,659

G

TIMP metallopeptidase inhibitor 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of TIMP1 mRNA]

NCBI chr X:3,766,509...3,772,578
Ensembl chr X:1,212,972...1,217,664

G

tight junction protein 1

multiple interactions

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of TJP1 protein

NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:118,849,838...119,094,432

G

talin rod domain containing 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TLNRD1 mRNA

NCBI chr 1:137,864,340...137,866,359
Ensembl chr 1:137,864,343...137,866,359

G

transmembrane protein with EGF-like and two follistatin-like domains 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TMEFF2 mRNA

NCBI chr 9:50,445,947...50,733,473
Ensembl chr 9:50,436,079...50,733,475

G

transmembrane protein 130

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TMEM130 mRNA

NCBI chr12:9,837,055...9,862,843
Ensembl chr12:9,837,055...9,862,840

G

transmembrane protein 35A

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TMEM35A mRNA

NCBI chr X:97,503,350...97,514,198
Ensembl chr X:97,503,350...97,514,197

G

transmembrane protein 50B

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TMEM50B mRNA

NCBI chr11:44,290,805...44,323,650
Ensembl chr11:30,804,837...30,837,661

G

transmembrane protein 63c

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TMEM63C mRNA

NCBI chr 6:106,667,389...106,738,778
Ensembl chr 6:106,672,934...106,736,990

G

thymosin beta 15B2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TMSB15B2 mRNA

NCBI chr X:105,090,980...105,093,094
Ensembl chr X:100,298,514...100,300,886

G

thioredoxin-related transmembrane protein 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TMX1 mRNA

NCBI chr 6:94,696,699...94,707,751
Ensembl chr 6:88,960,695...88,971,301

G

tumor necrosis factor

multiple interactions
increases expression

[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of TNF mRNA; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of TNF protein; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of TNF protein; butylbenzyl phthalate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of TNF mRNA]]
butylbenzyl phthalate results in increased expression of TNF mRNA

PMID:15256756 PMID:28595985 PMID:35739755 PMID:36746855 PMID:37364641

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629

G

TNF alpha induced protein 3

increases expression

butylbenzyl phthalate results in increased expression of TNFAIP3 mRNA

NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282

G

TNF alpha induced protein 6

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TNFAIP6 mRNA

NCBI chr 3:56,911,398...56,930,797
Ensembl chr 3:36,502,188...36,521,649

G

TNF receptor superfamily member 11B

multiple interactions

butylbenzyl phthalate promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased secretion of TNFRSF11B protein

PMID:31016361 PMID:38954831

NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:85,566,520...85,594,538

G

transducer of ERBB2, 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TOB2 mRNA

NCBI chr 7:115,242,843...115,251,563
Ensembl chr 7:113,361,148...113,372,688

G

torsin family 4, member A

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TOR4A mRNA

NCBI chr 3:8,004,292...8,007,979
Ensembl chr 3:8,002,023...8,008,042

G

tumor protein p53

increases methylation
multiple interactions
decreases expression

butylbenzyl phthalate results in increased methylation of TP53 promoter
[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of and results in increased phosphorylation of TP53 protein; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of TP53 mRNA
butylbenzyl phthalate results in decreased expression of TP53 mRNA

PMID:31016752 PMID:35487445 PMID:35739755

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524

G

triosephosphate isomerase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TPI1 mRNA

NCBI chr 4:159,301,558...159,305,088
Ensembl chr 4:157,615,386...157,619,541

G

TNF receptor-associated protein 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TRAP1 mRNA

NCBI chr10:11,971,259...12,005,306
Ensembl chr10:11,464,821...11,498,981

G

trafficking regulator of GLUT4 (SLC2A4) 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TRARG1 mRNA

NCBI chr10:62,019,281...62,039,666
Ensembl chr10:61,521,107...61,541,494

G

tribbles pseudokinase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TRIB1 mRNA

NCBI chr 7:93,096,001...93,102,547
Ensembl chr 7:91,206,579...91,214,731

G

tripartite motif containing 6

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TRIM6 mRNA

NCBI chr 1:168,095,619...168,108,809
Ensembl chr 1:158,683,746...158,696,914

G

transient receptor potential cation channel, subfamily C, member 6

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TRPC6 mRNA

NCBI chr 8:14,044,216...14,148,808
Ensembl chr 8:5,758,935...5,828,092

G

thymic stromal lymphopoietin

multiple interactions

[Dust results in increased abundance of butylbenzyl phthalate] which results in decreased methylation of TSLP promoter

NCBI chr18:24,723,990...24,728,419
Ensembl chr18:24,449,844...24,453,548

G

tweety family member 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TTYH1 mRNA

NCBI chr 1:79,125,564...79,144,137
Ensembl chr 1:70,053,324...70,071,845

G

tweety family member 3

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TTYH3 mRNA

NCBI chr12:19,110,973...19,139,379
Ensembl chr12:13,997,045...14,025,459

G

tubulin, beta 2B class IIb

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TUBB2B protein; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TUBB2B mRNA

PMID:31199487 PMID:37690569

NCBI chr17:30,747,734...30,750,781
Ensembl chr17:30,747,734...30,750,638

G

tubulin, beta 3 class III

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TUBB3 protein; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TUBB3 mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TUBB3 mRNA

PMID:31199487 PMID:37690569 PMID:39150890

NCBI chr19:68,365,687...68,374,741
Ensembl chr19:51,457,184...51,466,243

G

tubulin, beta 4A class IVa

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TUBB4A protein; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of TUBB4A mRNA
[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TUBB4A mRNA

PMID:31199487 PMID:37690569 PMID:39150890

NCBI chr 9:2,004,836...2,012,281
Ensembl chr 9:1,917,845...1,925,291

G

tubulin, beta 4B class IVb

decreases expression

butylbenzyl phthalate results in decreased expression of TUBB4B mRNA

NCBI chr 3:28,435,999...28,438,455
Ensembl chr 3:8,037,799...8,040,296

G

thioredoxin interacting protein

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TXNIP mRNA

NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:184,092,991...184,096,886

G

thioredoxin reductase 1

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of TXNRD1 mRNA

NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:20,830,045...20,907,863

G

ubiquitin associated and SH3 domain containing, B

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of UBASH3B mRNA

NCBI chr 8:50,282,510...50,430,034
Ensembl chr 8:41,388,341...41,532,201

G

UBX domain protein 11

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of UBXN11 mRNA

PMID:31199487 PMID:37690569

NCBI chr 5:146,329,666...146,353,529
Ensembl chr 5:146,329,842...146,353,526

G

uncoupling protein 1

multiple interactions

[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased expression of UCP1 mRNA

NCBI chr19:41,713,350...41,721,421
Ensembl chr19:24,808,783...24,816,852

G

unc-5 netrin receptor D

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of UNC5D mRNA

NCBI chr16:62,860,119...63,406,932
Ensembl chr16:62,860,174...63,401,143

G

ubiquitin specific peptidase 18

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of USP18 mRNA

NCBI chr 4:156,143,770...156,171,292
Ensembl chr 4:154,471,592...154,499,144

G

vesicle-associated membrane protein 5

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of VAMP5 mRNA

NCBI chr 4:104,423,813...104,435,059
Ensembl chr 4:104,423,820...104,426,212

G

vascular endothelial growth factor A

multiple interactions
decreases secretion
increases secretion

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [butylbenzyl phthalate results in increased secretion of VEGFA protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [butylbenzyl phthalate results in increased secretion of VEGFA protein]; butylbenzyl phthalate promotes the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]; SB 203580 inhibits the reaction [butylbenzyl phthalate results in increased secretion of VEGFA protein]; Wortmannin inhibits the reaction [butylbenzyl phthalate results in increased secretion of VEGFA protein]
butylbenzyl phthalate results in decreased secretion of VEGFA protein

PMID:18252963 PMID:25016925 PMID:30851587

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641

G

vascular endothelial growth factor D

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of VEGFD mRNA

NCBI chr X:33,704,582...33,740,305
Ensembl chr X:30,074,163...30,108,295

G

vestigial-like family member 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of VGLL4 mRNA

NCBI chr 4:149,598,151...149,711,186
Ensembl chr 4:147,927,034...148,038,471

G

vimentin

multiple interactions
increases expression

butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]]; HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of VIM protein]; trichostatin A inhibits the reaction [butylbenzyl phthalate promotes the reaction [[TCF4 protein binds to LEF1 protein] which binds to VIM protein]]

PMID:22552774 PMID:31212022

NCBI chr17:81,577,261...81,585,746
Ensembl chr17:76,668,647...76,677,187

G

VOPP1 WW domain binding protein

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of VOPP1 mRNA

NCBI chr 4:88,692,784...88,762,903
Ensembl chr 4:87,363,477...87,450,375

G

WD repeat domain 6

multiple interactions

[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate] affects the expression of WDR6 protein

NCBI chr 8:118,146,608...118,153,024
Ensembl chr 8:109,268,079...109,274,499

G

wolframin ER transmembrane glycoprotein

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of WFS1 mRNA

NCBI chr14:78,035,205...78,059,718
Ensembl chr14:73,810,404...73,835,602

G

Wnt family member 4

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of WNT4 mRNA]

NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:149,514,018...149,532,859

G

Wnt family member 6

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of WNT6 mRNA

NCBI chr 9:83,778,552...83,792,186
Ensembl chr 9:76,329,882...76,343,523

G

Wnt family member 9B

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of WNT9B mRNA

NCBI chr10:89,135,362...89,157,065
Ensembl chr10:88,635,331...88,657,035

G

WT1 transcription factor

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of WT1 mRNA

NCBI chr 3:112,019,721...112,068,454
Ensembl chr 3:91,567,001...91,613,643

G

xanthine dehydrogenase

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of XDH mRNA

NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:21,530,113...21,592,268

G

zinc finger and BTB domain containing 8b

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ZBTB8B mRNA

NCBI chr 5:141,765,925...141,781,619
Ensembl chr 5:141,766,309...141,781,600

G

zinc finger CCHC-type containing 12

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ZCCHC12 mRNA

NCBI chr X:120,299,138...120,302,465
Ensembl chr X:115,433,259...115,436,692

G

zinc finger DHHC-type palmitoyltransferase 23

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ZDHHC23 mRNA

NCBI chr11:70,224,581...70,240,971
Ensembl chr11:56,718,826...56,734,194

G

zinc finger E-box binding homeobox 1

multiple interactions
increases expression
increases stability

butylbenzyl phthalate results in increased expression of and results in increased stability of ZEB1 mRNA; MIR655 mRNA inhibits the reaction [butylbenzyl phthalate results in increased expression of ZEB1 mRNA]; ZEB1 protein affects the reaction [butylbenzyl phthalate results in increased expression of MMP2 protein]
butylbenzyl phthalate results in increased expression of ZEB1 protein
ATM protein affects the reaction [butylbenzyl phthalate results in increased expression of ZEB1 protein]; butylbenzyl phthalate results in increased expression of and affects the localization of ZEB1 protein; butylbenzyl phthalate results in increased expression of and results in increased stability of ZEB1 mRNA; MIR655 mRNA inhibits the reaction [butylbenzyl phthalate results in increased expression of ZEB1 protein]; ZEB1 protein affects the reaction [butylbenzyl phthalate results in increased expression of MMP2 protein]
butylbenzyl phthalate results in increased stability of ZEB1 protein

NCBI chr17:56,644,397...56,811,155
Ensembl chr17:51,948,948...52,115,214

G

zinc finger and AT hook domain containing

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in increased expression of ZFAT mRNA

NCBI chr 7:101,775,916...101,951,135
Ensembl chr 7:99,886,954...100,054,274

G

zinc finger protein 280B

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ZFP280B mRNA

NCBI chr20:12,627,106...12,641,943
Ensembl chr20:12,627,106...12,646,683

G

zinc finger protein 330

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ZFP330 mRNA

NCBI chr19:25,313,655...25,324,958
Ensembl chr19:25,313,655...25,324,958

G

zinc finger protein 467

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ZFP467 mRNA

NCBI chr 4:77,385,752...77,394,709
Ensembl chr 4:77,385,758...77,392,229

G

zinc finger protein 503

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ZFP503 mRNA

NCBI chr15:2,362,450...2,366,238
Ensembl chr15:2,313,060...2,316,848

G

zinc finger protein 791

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ZFP791 mRNA

NCBI chr19:39,921,848...39,942,507
Ensembl chr19:23,018,918...23,033,504

G

zona pellucida glycoprotein 2

multiple interactions

[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ZP2 mRNA

NCBI chr 1:183,944,840...183,956,619
Ensembl chr 1:174,513,511...174,525,288

camphene

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

caspase 3

multiple interactions

[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased cleavage of CASP3 protein]

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648

G

caspase 9

multiple interactions

[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased cleavage of CASP9 protein]

Ensembl chr 5:154,109,046...154,126,626

G

glutathione peroxidase 1

multiple interactions

[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of GPX1 mRNA]

NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024

G

glutathione-disulfide reductase

multiple interactions

[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased activity of GSR protein]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of GSR mRNA]

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661

G

nitric oxide synthase 2

multiple interactions

[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of NOS2 mRNA]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of NOS2 protein]

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210

G

8-oxoguanine DNA glycosylase

multiple interactions

[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of OGG1 protein]

NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:146,474,750...146,484,766

G

superoxide dismutase 1

multiple interactions

[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of SOD1 mRNA]

NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249

G

superoxide dismutase 2

multiple interactions

[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of SOD2 mRNA]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of SOD2 protein]

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189

CGP-42112A

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

angiotensinogen

multiple interactions

CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB mRNA]; CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB protein]; CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 mRNA]; CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 protein]; CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX4 mRNA]; CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX4 protein]; CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP mRNA]]; CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP protein]]; CGP 42112A promotes the reaction [[AGT protein co-treated with Rotenone] results in increased expression of AGTR2 protein]; CGP 42112A promotes the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTR2 mRNA]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB mRNA]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB protein]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 mRNA]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 protein]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX4 mRNA]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP mRNA]]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP protein]]]; PD 123319 inhibits the reaction [CGP 42112A promotes the reaction [[AGT protein co-treated with Rotenone] results in increased expression of AGTR2 protein]]; PD 123319 inhibits the reaction [CGP 42112A promotes the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTR2 mRNA]]]

NCBI chr19:69,426,540...69,447,017
Ensembl chr19:52,529,185...52,540,977

G

angiotensin II receptor, type 2

multiple interactions

CGP 42112A promotes the reaction [[AGT protein co-treated with Rotenone] results in increased expression of AGTR2 protein]; CGP 42112A promotes the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTR2 mRNA]]; PD 123319 inhibits the reaction [CGP 42112A promotes the reaction [[AGT protein co-treated with Rotenone] results in increased expression of AGTR2 protein]]; PD 123319 inhibits the reaction [CGP 42112A promotes the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTR2 mRNA]]]
[CGP 42112A binds to and results in increased activity of AGTR2 protein] which affects the susceptibility to Phenylephrine; [CGP 42112A binds to and results in increased activity of AGTR2 protein] which results in increased abundance of and results in increased secretion of Triglycerides; [CGP 42112A binds to and results in increased activity of AGTR2 protein] which results in increased abundance of Fatty Acids, Nonesterified; CGP 42112A binds to and results in increased activity of AGTR2 protein

PMID:16003179 PMID:19151255 PMID:25446015

NCBI chr X:116,914,320...116,918,504
Ensembl chr X:112,120,228...112,124,057

G

angiotensin II receptor-associated protein

multiple interactions

CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP mRNA]]; CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP protein]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP mRNA]]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [AGT protein promotes the reaction [Rotenone results in increased expression of AGTRAP protein]]]

NCBI chr 5:163,790,565...163,802,174
Ensembl chr 5:158,508,749...158,519,036

G

cytochrome b-245 beta chain

multiple interactions

CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB mRNA]; CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB protein]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB mRNA]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of CYBB protein]]

NCBI chr X:16,030,596...16,065,065
Ensembl chr X:13,359,430...13,392,586

G

NADPH oxidase 1

multiple interactions

CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 mRNA]; CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 protein]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 mRNA]]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX1 protein]]

NCBI chr X:101,572,338...101,625,571
Ensembl chr X:97,279,056...97,302,236

G

NADPH oxidase 4

multiple interactions

CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX4 mRNA]; CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX4 protein]; PD 123319 inhibits the reaction [CGP 42112A inhibits the reaction [[AGT protein co-treated with Rotenone] results in increased expression of NOX4 mRNA]]

NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:140,901,097...141,077,406

G

ubiquitin conjugating enzyme E2 V2

increases expression

CGP 42112A results in increased expression of UBE2V2 mRNA; CGP 42112A results in increased expression of UBE2V2 protein

NCBI chr11:98,808,681...98,842,583
Ensembl chr11:85,304,526...85,336,369

citral

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-fetoprotein

multiple interactions

citral inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein]

NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,573,412...17,591,480

G

aldo-keto reductase family 1, member C2

increases expression
increases activity

citral results in increased expression of AKR1C2 mRNA
citral results in increased activity of AKR1C2 promoter

PMID:20491607 PMID:21195160

NCBI chr17:70,669,684...70,717,935
Ensembl chr17:65,759,788...65,775,764

G

aldehyde dehydrogenase 1 family, member A2

increases oxidation

ALDH1A2 protein results in increased oxidation of citral

NCBI chr 8:80,758,641...80,837,891
Ensembl chr 8:71,877,850...71,957,107

G

catalase

multiple interactions

citral inhibits the reaction [Diethylnitrosamine results in decreased expression of CAT protein]

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478

G

CD86 molecule

increases expression

citral results in increased expression of CD86 protein

NCBI chr11:77,647,565...77,706,178
Ensembl chr11:64,163,828...64,200,818

G

CEA cell adhesion molecule 20

multiple interactions

citral inhibits the reaction [Diethylnitrosamine results in increased expression of CEACAM20 protein]

NCBI chr 1:79,622,077...79,643,782
Ensembl chr 1:79,622,077...79,643,782

G

C-X-C motif chemokine ligand 2

increases expression

citral results in increased expression of CXCL2 protein

NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,181,062...17,183,075

G

cytochrome b5 type A

multiple interactions

citral inhibits the reaction [Diethylnitrosamine results in increased expression of CYB5A protein]

NCBI chr18:80,487,923...80,520,544
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535

G

cytochrome P450, family 1, subfamily a, polypeptide 1

multiple interactions

[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [CYP1A1 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of citral

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily b, polypeptide 1

multiple interactions

[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite

NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 2, subfamily b, polypeptide 1

decreases activity

citral results in decreased activity of CYP2B1 protein

NCBI chr 1:90,646,098...90,669,762
Ensembl chr 1:81,518,408...81,542,052

G

cytochrome P450, family 2, subfamily b, polypeptide 3

multiple interactions

[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [CYP2B6 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; citral inhibits the reaction [CYP2B6 protein results in increased hydrolysis of Bupropion]

PMID:18611395 PMID:18824010

NCBI chr 1:90,780,468...90,859,852
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions

[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions

citral inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]

NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 3, subfamily a, polypeptide 9

multiple interactions

[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [CYP3A5 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of citral

NCBI chr12:21,919,955...21,960,160
Ensembl chr12:16,806,207...16,846,422

G

DnaJ heat shock protein family (Hsp40) member B4

increases expression

citral results in increased expression of DNAJB4 mRNA

NCBI chr 2:243,790,296...243,819,042
Ensembl chr 2:241,130,340...241,159,089

G

estrogen receptor 1

affects binding
multiple interactions

citral binds to ESR1 protein
citral inhibits the reaction [Estradiol binds to ESR1 protein]

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

affects binding
multiple interactions

citral binds to ESR2 protein
citral inhibits the reaction [Estradiol binds to ESR2 protein]

NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919

G

glutamate cysteine ligase, modifier subunit

increases expression

citral results in increased expression of GCLM mRNA

NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535

G

glutamic--pyruvic transaminase

multiple interactions

citral inhibits the reaction [Diethylnitrosamine results in increased expression of GPT protein]

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494

G

glutathione-disulfide reductase

multiple interactions

citral inhibits the reaction [Diethylnitrosamine results in decreased expression of GSR protein]

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661

G

heme oxygenase 1

increases expression

citral results in increased expression of HMOX1 mRNA

PMID:20491607 PMID:26244607

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079

G

homeobox A1

multiple interactions

citral inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]

NCBI chr 4:82,586,505...82,589,209
Ensembl chr 4:81,255,883...81,258,504

G

intercellular adhesion molecule 1

increases expression

citral results in increased expression of ICAM1 protein

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438

G

interferon gamma

multiple interactions

[citral co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375

G

interleukin 18

increases expression

citral results in increased expression of IL18 protein

NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 1 alpha

increases expression

citral results in increased expression of IL1A protein

NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 2

increases secretion
multiple interactions

citral results in increased secretion of IL2 protein
[citral co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA

PMID:22245253 PMID:29594315

NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 6

increases secretion

citral results in increased secretion of IL6 protein

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178

G

MAF bZIP transcription factor F

increases expression

citral results in increased expression of MAFF mRNA

NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:110,912,499...110,923,851

G

NAD(P)H quinone dehydrogenase 1

increases activity

citral results in increased activity of NQO1 protein

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557

G

proliferating cell nuclear antigen

multiple interactions

citral inhibits the reaction [Diethylnitrosamine results in increased expression of PCNA protein]

NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:119,498,810...119,502,995

G

cytochrome p450 oxidoreductase

multiple interactions

citral inhibits the reaction [Diethylnitrosamine results in increased expression of POR protein]

NCBI chr12:26,587,674...26,655,612
Ensembl chr12:20,951,058...20,999,245

G

vascular endothelial growth factor A

increases expression

citral results in increased expression of VEGFA protein

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641

citral dimethyl acetal

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

G protein subunit alpha 15

increases response to substance
multiple interactions

GNA15 protein results in increased susceptibility to citral dimethyl acetal
[GNA15 protein results in increased susceptibility to citral dimethyl acetal] which results in increased activity of OR1A1B protein

NCBI chr 7:8,835,396...8,856,269
Ensembl chr 7:8,184,861...8,205,508

G

olfactory receptor family 1 subfamily A member 1

multiple interactions

[GNA15 protein results in increased susceptibility to citral dimethyl acetal] which results in increased activity of OR1A1B protein

NCBI chr10:59,557,386...59,558,324
Ensembl chr10:59,052,828...59,060,676

Crotoxyphos

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetylcholinesterase

multiple interactions
decreases activity

[crotoxyphos co-treated with Dichlorvos] results in decreased activity of ACHE protein
crotoxyphos results in decreased activity of ACHE protein

NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651

decanal

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aldo-keto reductase family 1 member B1

affects reduction
increases reduction

AKR1B1 protein affects the reduction of decanaldehyde
AKR1B1 protein results in increased reduction of decanaldehyde

PMID:9890881 PMID:11306073

NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:62,932,031...62,946,157

G

aldehyde dehydrogenase 1 family, member A2

increases oxidation

ALDH1A2 protein results in increased oxidation of decanaldehyde

NCBI chr 8:80,758,641...80,837,891
Ensembl chr 8:71,877,850...71,957,107

G

aldehyde dehydrogenase 2 family member

increases metabolic processing

ALDH2 protein results in increased metabolism of decanaldehyde

NCBI chr12:40,610,244...40,643,220
Ensembl chr12:34,901,219...34,982,521

G

G protein subunit alpha L

multiple interactions
increases response to substance

[GNAL protein results in increased susceptibility to decanaldehyde] which results in increased activity of OR1A1B protein

NCBI chr18:62,892,257...63,032,510
Ensembl chr18:60,622,311...60,762,599

G

olfactory receptor family 1 subfamily A member 1

multiple interactions

[GNAL protein results in increased susceptibility to decanaldehyde] which results in increased activity of OR1A1B protein

NCBI chr10:59,557,386...59,558,324
Ensembl chr10:59,052,828...59,060,676

galaxolide

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

androgen receptor

multiple interactions

galaxolide binds to and results in decreased activity of AR protein; galaxolide inhibits the reaction [Metribolone results in increased activity of AR protein]

PMID:15537743 PMID:17762842 PMID:29427707

NCBI chr X:67,135,317...67,304,476
Ensembl chr X:63,104,771...63,273,925

G

carboxylesterase 1D

decreases activity

galaxolide results in decreased activity of CES1 protein

NCBI chr19:30,046,494...30,085,039
Ensembl chr19:13,796,623...13,912,035

G

cytochrome P450, family 17, subfamily a, polypeptide 1

multiple interactions
decreases expression
increases activity
decreases activity

[galaxolide co-treated with Cyclic AMP] results in decreased activity of CYP17A1 protein; [galaxolide co-treated with Cyclic AMP] results in increased activity of CYP17A1 protein
galaxolide results in decreased expression of CYP17A1 mRNA
galaxolide results in increased activity of CYP17A1 protein
galaxolide results in decreased activity of CYP17A1 protein

PMID:23084589 PMID:37797914

NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:245,535,462...245,541,573

G

7-dehydrocholesterol reductase

decreases expression

galaxolide results in decreased expression of DHCR7 mRNA

NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:199,015,081...199,031,055

G

DMRT-like family C1c1

increases expression

galaxolide results in increased expression of DMRTC1C1 mRNA

NCBI chr X:67,896,973...67,904,182
Ensembl chr X:67,896,974...67,904,182

G

DnaJ heat shock protein family (Hsp40) member C19

decreases expression

galaxolide results in decreased expression of DNAJC19 mRNA

NCBI chr 2:118,851,497...118,875,813
Ensembl chr 2:116,923,272...116,945,264

G

epidermal growth factor receptor

increases expression
multiple interactions

galaxolide results in increased expression of EGFR mRNA
[galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of EGFR mRNA

NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382

G

estrogen receptor 1

multiple interactions

galaxolide binds to and results in increased activity of ESR1 protein

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

multiple interactions

galaxolide binds to and results in decreased activity of ESR2 protein

NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919

G

follicle stimulating hormone subunit beta

increases expression

galaxolide results in increased expression of FSHB protein

NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:93,548,560...93,552,370

G

follicle stimulating hormone receptor

increases expression

galaxolide results in increased expression of FSHR mRNA

NCBI chr 6:10,952,329...11,160,288
Ensembl chr 6:5,198,825...5,406,785

G

gonadotropin releasing hormone receptor

increases expression

galaxolide results in increased expression of GNRHR mRNA

NCBI chr14:22,211,666...22,229,654
Ensembl chr14:21,856,871...21,874,861

G

hypoxia inducible factor 1 subunit alpha

increases expression
multiple interactions

galaxolide results in increased expression of HIF1A mRNA
[galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of HIF1A mRNA; galaxolide inhibits the reaction [acetyl methyl tetramethyl tetralin results in increased expression of HIF1A mRNA]; galaxolide inhibits the reaction [acetyl methyl tetramethyl tetralin results in increased expression of HIF1A protein]

NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2

multiple interactions
decreases expression

[galaxolide results in decreased expression of [HSD3B2 co-treated with CYP21A2]] which results in decreased chemical synthesis of Hydrocortisone; [galaxolide results in decreased expression of [HSD3B2 co-treated with CYP21A2]] which results in decreased chemical synthesis of Progesterone
galaxolide results in decreased expression of HSD3B2

NCBI chr 2:188,784,614...188,812,535
Ensembl chr 2:186,095,897...186,101,852

G

interleukin 6

increases expression
multiple interactions

galaxolide results in increased expression of IL6 mRNA
[galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of IL6 mRNA

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178

G

Janus kinase 2

increases expression
multiple interactions

galaxolide results in increased expression of JAK2 mRNA
[galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of JAK2 mRNA

NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189

G

kinase insert domain receptor

multiple interactions

[galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of KDR mRNA

NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,217,871...32,261,018

G

luteinizing hormone subunit beta

increases expression

galaxolide results in increased expression of LHB protein

NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972

G

mitogen activated protein kinase kinase kinase 2

increases expression

galaxolide results in increased expression of MAP3K2 mRNA

NCBI chr18:24,081,444...24,153,940
Ensembl chr18:23,807,218...23,871,433

G

microRNA 155

multiple interactions

[galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of MIR155 mRNA; galaxolide inhibits the reaction [acetyl methyl tetramethyl tetralin results in increased expression of MIR155 mRNA]

NCBI chr11:37,261,114...37,261,178
Ensembl chr11:23,774,654...23,774,718

G

microRNA 17

decreases expression
multiple interactions

galaxolide results in decreased expression of MIR17 mRNA
[galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in decreased expression of MIR17 mRNA

NCBI chr15:98,587,848...98,587,931
Ensembl chr15:92,180,629...92,180,712

G

microRNA 19b-1

decreases expression
multiple interactions

galaxolide results in decreased expression of MIR19B1 mRNA
[galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in decreased expression of MIR19B1 mRNA

NCBI chr15:98,588,433...98,588,519
Ensembl chr15:92,181,214...92,181,300

G

microRNA 20a

multiple interactions
decreases expression

[galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in decreased expression of MIR20A mRNA
galaxolide results in decreased expression of MIR20A mRNA

NCBI chr15:98,588,303...98,588,387
Ensembl chr15:92,181,084...92,181,168

G

microRNA 92a-1

decreases expression
multiple interactions

galaxolide results in decreased expression of MIR92A1 mRNA
[galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in decreased expression of MIR92A1 mRNA

NCBI chr15:98,588,555...98,588,632
Ensembl chr15:92,181,336...92,181,413

G

microRNA 93

multiple interactions

[galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of MIR93 mRNA; galaxolide promotes the reaction [acetyl methyl tetramethyl tetralin results in increased expression of MIR93 mRNA]

NCBI chr12:22,156,844...22,156,930
Ensembl chr12:17,043,135...17,043,221

G

matrix metallopeptidase 3

increases expression
multiple interactions

galaxolide results in increased expression of MMP3 mRNA
[galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of MMP3 mRNA

NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:4,640,416...4,653,961

G

matrix metallopeptidase 9

multiple interactions
increases expression

[galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of MMP9 mRNA; [galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of MMP9 protein
galaxolide results in increased expression of MMP9 mRNA; galaxolide results in increased expression of MMP9 protein

NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120

G

progesterone receptor

multiple interactions

galaxolide binds to and results in decreased activity of PGR protein

NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:6,072,673...6,131,344

G

snail family transcriptional repressor 1

increases expression
multiple interactions

galaxolide results in increased expression of SNAI1 mRNA
[galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of SNAI1 mRNA

NCBI chr 3:176,667,476...176,671,965
Ensembl chr 3:156,248,485...156,252,969

G

snail family transcriptional repressor 2

multiple interactions
increases expression

[galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of SNAI2 mRNA; galaxolide promotes the reaction [acetyl methyl tetramethyl tetralin results in increased expression of SNAI2 mRNA]
galaxolide results in increased expression of SNAI2 mRNA

NCBI chr11:99,686,934...99,690,349
Ensembl chr11:86,181,909...86,186,200

G

superoxide dismutase 1

decreases expression

galaxolide results in decreased expression of SOD1 protein

NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249

G

steroid 5 alpha-reductase 2

decreases expression

galaxolide results in decreased expression of SRD5A2 mRNA

NCBI chr 6:27,178,089...27,217,588
Ensembl chr 6:21,426,215...21,462,112

G

signal transducer and activator of transcription 3

increases expression
multiple interactions

galaxolide results in increased expression of STAT3 mRNA
[galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of STAT3 mRNA

NCBI chr10:86,311,528...86,363,513
Ensembl chr10:85,811,218...85,863,057

G

testis expressed 14, intercellular bridge forming factor

decreases expression

galaxolide results in decreased expression of TEX14 mRNA

NCBI chr10:72,729,017...72,859,697
Ensembl chr10:72,231,801...72,355,805

G

vascular endothelial growth factor A

multiple interactions
increases expression

[galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of VEGFA mRNA; galaxolide inhibits the reaction [acetyl methyl tetramethyl tetralin results in increased expression of VEGFA protein]
galaxolide results in increased expression of VEGFA mRNA

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641

G

vimentin

multiple interactions
increases expression

[galaxolide co-treated with acetyl methyl tetramethyl tetralin] results in increased expression of VIM mRNA; galaxolide inhibits the reaction [acetyl methyl tetramethyl tetralin results in increased expression of VIM mRNA]
galaxolide results in increased expression of VIM mRNA

NCBI chr17:81,577,261...81,585,746
Ensembl chr17:76,668,647...76,677,187

G

zinc finger E-box binding homeobox 1

multiple interactions
increases expression

acetyl methyl tetramethyl tetralin promotes the reaction [galaxolide results in increased expression of ZEB1 mRNA]; galaxolide promotes the reaction [acetyl methyl tetramethyl tetralin results in increased expression of ZEB1 mRNA]

NCBI chr17:56,644,397...56,811,155
Ensembl chr17:51,948,948...52,115,214

geraniol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily C member 2

multiple interactions

geraniol inhibits the reaction [Fructose results in decreased expression of ABCC2 mRNA]; geraniol inhibits the reaction [Fructose results in decreased expression of ABCC2 protein]

NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238

G

acetyl-CoA carboxylase alpha

decreases expression

geraniol results in decreased expression of ACACA mRNA

NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,014,170...69,276,457

G

acetylcholinesterase

multiple interactions

geraniol inhibits the reaction [Acrylamide results in increased activity of ACHE protein]; geraniol inhibits the reaction [Streptozocin results in increased activity of ACHE protein]

PMID:24752916 PMID:25199698

NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651

G

actin alpha 2, smooth muscle

multiple interactions

geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ACTA2 mRNA]

NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554

G

actin-like 6A

decreases expression

geraniol results in decreased expression of ACTL6A mRNA

NCBI chr 2:117,413,206...117,436,758
Ensembl chr 2:115,492,285...115,508,401

G

activin A receptor type 1

increases expression

geraniol results in increased expression of ACVR1 mRNA

NCBI chr 3:63,387,378...63,506,980
Ensembl chr 3:42,978,561...43,098,241

G

adiponectin, C1Q and collagen domain containing

multiple interactions

geraniol inhibits the reaction [Fructose results in decreased secretion of ADIPOQ protein]; geraniol promotes the reaction [Streptozocin results in decreased expression of ADIPOQ protein]

PMID:25679220 PMID:28178614

NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564

G

ALF transcription elongation factor 4

increases expression

geraniol results in increased expression of AFF4 mRNA

NCBI chr10:37,498,825...37,579,751
Ensembl chr10:37,498,825...37,579,751

G

advanced glycosylation end product-specific receptor

multiple interactions

geraniol inhibits the reaction [Fructose results in increased expression of AGER protein]

NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,147,890...4,151,078

G

AT hook containing transcription factor 1

decreases expression

geraniol results in decreased expression of AHCTF1 mRNA

NCBI chr13:94,013,894...94,068,348
Ensembl chr13:91,481,936...91,536,391

G

aldo-keto reductase family 1, member C1

increases expression

geraniol results in increased expression of AKR1C1 mRNA

NCBI chr17:70,720,397...70,747,285
Ensembl chr17:65,810,475...65,837,326

G

adaptor related protein complex 5 subunit zeta 1

increases expression

geraniol results in increased expression of AP5Z1 mRNA

NCBI chr12:17,207,315...17,222,975
Ensembl chr12:12,093,834...12,108,511

G

amyloid beta precursor protein binding family B member 2

increases expression

geraniol results in increased expression of APBB2 mRNA

NCBI chr14:41,557,918...41,878,622
Ensembl chr14:41,557,972...41,877,495

G

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

decreases expression

geraniol results in decreased expression of APPL1 mRNA

NCBI chr16:2,125,234...2,173,457
Ensembl chr16:2,121,255...2,166,692

G

activating transcription factor 3

increases expression

geraniol results in increased expression of ATF3 mRNA

NCBI chr13:105,274,103...105,331,653
Ensembl chr13:102,751,321...102,764,631

G

activating transcription factor 4

multiple interactions

geraniol inhibits the reaction [Rotenone results in increased expression of ATF4 protein]

NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:111,804,183...111,806,446

G

activating transcription factor 6

increases expression
multiple interactions

geraniol results in increased expression of ATF6 mRNA
geraniol inhibits the reaction [Rotenone results in increased expression of ATF6 protein]

PMID:27683099 PMID:30141137

NCBI chr13:85,460,312...85,639,959
Ensembl chr13:82,930,034...83,107,177

G

autophagy related 12

multiple interactions

geraniol inhibits the reaction [Rotenone results in decreased expression of ATG12 protein]

NCBI chr18:41,638,841...41,649,311
Ensembl chr18:39,452,191...39,462,418

G

autophagy related 5

multiple interactions

geraniol inhibits the reaction [Rotenone results in decreased expression of ATG5 protein]

NCBI chr20:49,380,835...49,471,826
Ensembl chr20:47,798,290...47,889,209

G

autophagy related 7

multiple interactions

geraniol inhibits the reaction [Rotenone results in decreased expression of ATG7 protein]

NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:147,718,752...147,925,593

G

BCL2-antagonist/killer 1

increases expression

geraniol results in increased expression of BAK1 protein

NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,100,480...5,109,264

G

BCL2 associated X, apoptosis regulator

multiple interactions
increases expression

geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of BAX mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of BAX protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in decreased expression of BAX protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of BAX protein]
geraniol inhibits the reaction [Doxorubicin results in increased expression of BAX mRNA]
geraniol results in increased expression of BAX mRNA; geraniol results in increased expression of BAX protein

PMID:21371438 PMID:22760862 PMID:24768735 PMID:29050341 PMID:29745075 More...

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368

G

bromodomain adjacent to zinc finger domain, 1B

decreases expression

geraniol results in decreased expression of BAZ1B mRNA

NCBI chr12:27,068,541...27,126,511
Ensembl chr12:21,431,985...21,490,426

G

bromodomain adjacent to zinc finger domain, 2B

increases expression

geraniol results in increased expression of BAZ2B mRNA

NCBI chr 3:44,384,282...44,681,619
Ensembl chr 3:44,385,474...44,592,908

G

BBX high mobility group box domain containing

increases expression

geraniol results in increased expression of BBX mRNA

NCBI chr11:50,381,249...50,628,934
Ensembl chr11:50,381,247...50,623,251

G

BCL11 transcription factor A

decreases expression

geraniol results in decreased expression of BCL11A mRNA

NCBI chr14:102,230,147...102,325,289
Ensembl chr14:98,030,461...98,124,180

G

BCL2, apoptosis regulator

multiple interactions
decreases expression
increases expression

geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BCL2 mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BCL2 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of BCL2 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of BCL2 protein]
geraniol inhibits the reaction [Doxorubicin results in decreased expression of BCL2 mRNA]
geraniol results in decreased expression of BCL2 mRNA; geraniol results in decreased expression of BCL2 protein
geraniol results in increased expression of BCL2 protein

PMID:21371438 PMID:21445532 PMID:22760862 PMID:24768735 PMID:29050341 More...

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 1

multiple interactions

geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of BCL2L1 protein]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of BCL2L1 mRNA]

PMID:26695085 PMID:35608392

NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479

G

Bcl2-like 2

decreases expression

geraniol results in decreased expression of BCL2L2 protein

NCBI chr15:32,326,686...32,337,834
Ensembl chr15:28,356,807...28,361,624

G

BCL6, transcription repressor

increases expression

geraniol results in increased expression of BCL6 mRNA

NCBI chr11:90,358,753...90,382,049
Ensembl chr11:76,854,090...76,877,389

G

BCL2-associated transcription factor 1

decreases expression

geraniol results in decreased expression of BCLAF1 mRNA

NCBI chr 1:16,904,572...16,937,106
Ensembl chr 1:15,070,894...15,148,832

G

brain-derived neurotrophic factor

multiple interactions

geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF mRNA]; geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF protein]

NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615

G

baculoviral IAP repeat-containing 5

decreases expression

geraniol results in decreased expression of BIRC5 mRNA

NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380

G

basic helix-loop-helix ARNT like 1

increases expression

geraniol results in increased expression of BMAL1 mRNA

NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:167,331,633...167,430,231

G

bone morphogenetic protein 6

increases expression

geraniol results in increased expression of BMP6 mRNA

NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,318,569...26,470,365

G

BCL2 interacting protein 3

increases expression

geraniol results in increased expression of BNIP3 protein

NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:193,708,167...193,725,359

G

BRCA1, DNA repair associated

decreases expression

geraniol results in decreased expression of BRCA1 mRNA

NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,418,000...86,477,304

G

BRCA2, DNA repair associated

decreases expression

geraniol results in decreased expression of BRCA2 mRNA

NCBI chr12:4,895,092...4,939,340
Ensembl chr12:59,819...100,567

G

basic transcription factor 3

decreases expression

geraniol results in decreased expression of BTF3 mRNA

NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
Ensembl chr13:29,659,231...29,666,879

G

BUB1 mitotic checkpoint serine/threonine kinase

decreases expression

geraniol results in decreased expression of BUB1 mRNA

NCBI chr 3:135,473,525...135,504,921
Ensembl chr 3:115,020,254...115,051,650

G

BUB1 mitotic checkpoint serine/threonine kinase B

decreases expression

geraniol results in decreased expression of BUB1B mRNA

NCBI chr 3:126,017,019...126,069,470
Ensembl chr 3:105,563,138...105,615,547

G

caspase 3

multiple interactions
increases activity
increases expression

[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased cleavage of CASP3 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of CASP3 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP3 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP3 mRNA]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased activity of CASP3 protein]; geraniol inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein]
geraniol results in increased activity of CASP3 protein
geraniol results in increased expression of CASP3 mRNA; geraniol results in increased expression of CASP3 protein
geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CASP3 protein]
geraniol results in increased expression of CASP3 protein modified form

PMID:21371438 PMID:21907755 PMID:22509279 PMID:24875281 PMID:26154255 More...

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648

G

caspase 8

multiple interactions
increases expression

geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP8 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP8 mRNA]
geraniol results in increased expression of CASP8 mRNA; geraniol results in increased expression of CASP8 protein

PMID:21907755 PMID:30506710

NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542

G

caspase 9

multiple interactions
increases expression

[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased cleavage of CASP9 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of CASP9 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP9 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP9 mRNA]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased activity of CASP9 protein]; geraniol inhibits the reaction [Doxorubicin results in increased cleavage of CASP9 protein]
geraniol results in increased expression of CASP9 mRNA; geraniol results in increased expression of CASP9 protein
geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CASP9 mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CASP9 protein]

PMID:21907755 PMID:22509279 PMID:24768735 PMID:26364502 PMID:26695085 More...

Ensembl chr 5:154,109,046...154,126,626

G

catalase

multiple interactions
decreases activity
increases activity

geraniol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CAT protein]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased activity of CAT protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CAT protein]
geraniol results in decreased activity of CAT protein
geraniol results in increased activity of CAT protein
geraniol inhibits the reaction [2-Acetylaminofluorene results in decreased activity of CAT protein]; geraniol inhibits the reaction [ferric nitrilotriacetate results in decreased activity of CAT protein]; geraniol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of CAT mRNA]; geraniol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]

PMID:21907755 PMID:22760862 PMID:23033690 PMID:23399806 PMID:24752916 More...

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478

G

CBFA2/RUNX1 partner transcriptional co-repressor 2

increases expression

geraniol results in increased expression of CBFA2T2 mRNA

NCBI chr 3:163,397,160...163,503,409
Ensembl chr 3:142,936,985...143,043,197

G

core-binding factor subunit beta

decreases expression

geraniol results in decreased expression of CBFB mRNA

NCBI chr19:49,955,133...50,002,661
Ensembl chr19:33,049,172...33,092,751

G

C-C motif chemokine ligand 4

increases secretion

geraniol results in increased secretion of CCL4 protein

NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,452,052...68,468,231

G

cyclin A2

decreases expression

geraniol results in decreased expression of CCNA2 mRNA; geraniol results in decreased expression of CCNA2 protein

PMID:17138864 PMID:27683099

NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:119,426,089...119,433,577

G

cyclin B1

decreases expression

geraniol results in decreased expression of CCNB1 protein

PMID:17138864 PMID:21371438

NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:31,912,193...31,921,172

G

cyclin D1

decreases expression

geraniol results in decreased expression of CCND1 protein

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602

G

CD86 molecule

increases expression

geraniol results in increased expression of CD86 protein

NCBI chr11:77,647,565...77,706,178
Ensembl chr11:64,163,828...64,200,818

G

cell division cycle 20

decreases expression

geraniol results in decreased expression of CDC20 mRNA

NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:131,966,215...131,970,512

G

cell division cycle 25A

decreases expression

geraniol results in decreased expression of CDC25A mRNA

NCBI chr 8:118,742,824...118,761,190
Ensembl chr 8:109,864,478...109,882,701

G

cell division cycle 25C

decreases expression

geraniol results in decreased expression of CDC25C mRNA

NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,335,834...26,356,185

G

cell division cycle 45

decreases expression

geraniol results in decreased expression of CDC45 mRNA

NCBI chr11:95,689,702...95,714,980
Ensembl chr11:82,185,473...82,210,619

G

cell division cycle 7

decreases expression

geraniol results in decreased expression of CDC7 mRNA

NCBI chr14:2,949,538...2,969,656
Ensembl chr14:2,804,661...2,824,778

G

cadherin 1

multiple interactions

geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 protein]

NCBI chr19:51,402,178...51,471,572
Ensembl chr19:34,492,371...34,561,775

G

cyclin-dependent kinase 1

decreases expression

geraniol results in decreased expression of CDK1 protein

NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,266,248...19,281,408

G

cyclin dependent kinase 2

decreases expression
multiple interactions

geraniol results in decreased expression of CDK2 mRNA; geraniol results in decreased expression of CDK2 protein
geraniol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein]; geraniol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein]

PMID:15450939 PMID:17138864 PMID:27683099

NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,129,811...1,137,403

G

cyclin-dependent kinase 4

decreases expression

geraniol results in decreased expression of CDK4 protein

PMID:15450939 PMID:21371438

NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase inhibitor 1A

increases expression
multiple interactions
increases response to substance

geraniol results in increased expression of CDKN1A protein
geraniol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein]
CDKN1A protein results in increased susceptibility to geraniol

PMID:17138864 PMID:21371438

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1B

increases expression
multiple interactions
increases response to substance

geraniol results in increased expression of CDKN1B protein
geraniol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein]
CDKN1B protein results in increased susceptibility to geraniol

PMID:17138864 PMID:21371438

NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982

G

cyclin-dependent kinase inhibitor 2C

decreases expression

geraniol results in decreased expression of CDKN2C mRNA

NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:124,411,124...124,416,278

G

cyclin-dependent kinase inhibitor 3

decreases expression

geraniol results in decreased expression of CDKN3 mRNA

NCBI chr15:22,502,299...22,513,725
Ensembl chr15:20,022,664...20,033,945

G

chromatin licensing and DNA replication factor 1

decreases expression

geraniol results in decreased expression of CDT1 mRNA

NCBI chr19:67,529,249...67,534,195
Ensembl chr19:50,620,713...50,625,659

G

CCAAT/enhancer binding protein beta

increases expression

geraniol results in increased expression of CEBPB mRNA

NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:156,397,052...156,399,473

G

CCAAT/enhancer binding protein gamma

increases expression

geraniol results in increased expression of CEBPG mRNA

NCBI chr 1:96,820,981...96,829,736
Ensembl chr 1:87,684,019...87,694,569

G

centromere protein E

decreases expression

geraniol results in decreased expression of CENPE mRNA

NCBI chr 2:226,310,970...226,369,636
Ensembl chr 2:223,636,998...223,695,669

G

centromere protein F

decreases expression

geraniol results in decreased expression of CENPF mRNA

NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669

G

checkpoint kinase 1

decreases expression

geraniol results in decreased expression of CHEK1 mRNA

NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:36,420,569...36,441,009

G

citron rho-interacting serine/threonine kinase

decreases expression

geraniol results in decreased expression of CIT mRNA

NCBI chr12:46,263,881...46,425,642
Ensembl chr12:40,605,563...40,763,860

G

creatine kinase, M-type

multiple interactions

geraniol inhibits the reaction [Doxorubicin results in increased activity of CKM protein]

NCBI chr 1:88,189,382...88,199,717
Ensembl chr 1:79,061,456...79,071,720

G

CCHC-type zinc finger, nucleic acid binding protein

decreases expression

geraniol results in decreased expression of CNBP mRNA

NCBI chr 4:121,860,102...121,868,976
Ensembl chr 4:120,302,771...120,311,637

G

cyclic nucleotide gated channel subunit alpha 2

multiple interactions

CNGA2 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]

NCBI chr X:154,741,742...154,759,814
Ensembl chr X:149,696,997...149,715,051

G

collagen type I alpha 1 chain

multiple interactions

geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]

NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624

G

cytochrome c oxidase subunit 7C

multiple interactions

geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of COX7C mRNA]

NCBI chr 2:18,577,145...18,579,170
Ensembl chr 2:16,840,837...16,843,760

G

cAMP responsive element binding protein 3

increases expression

geraniol results in increased expression of CREB3 mRNA

NCBI chr 5:62,613,652...62,619,019
Ensembl chr 5:57,817,832...57,824,390

G

cAMP responsive element binding protein 3-like 2

increases expression

geraniol results in increased expression of CREB3L2 mRNA

NCBI chr 4:66,874,623...66,990,962
Ensembl chr 4:65,907,655...66,023,763

G

C-reactive protein

multiple interactions

geraniol inhibits the reaction [Isoproterenol results in increased expression of CRP protein]

NCBI chr13:87,694,062...87,695,978
Ensembl chr13:85,124,977...85,175,178

G

catenin beta 1

multiple interactions

geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CTNNB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein]

PMID:26165751 PMID:28428697

NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111

G

cathepsin D

multiple interactions

geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased activity of CTSD protein]

NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:197,527,467...197,539,488

G

cytochrome b5 type A

multiple interactions

geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased activity of CYB5A protein]

NCBI chr18:80,487,923...80,520,544
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535

G

cytochrome b-245 beta chain

multiple interactions

geraniol inhibits the reaction [Dietary Fats results in increased expression of CYBB protein]
geraniol inhibits the reaction [Palmitic Acid results in increased expression of CYBB protein]

NCBI chr X:16,030,596...16,065,065
Ensembl chr X:13,359,430...13,392,586

G

cytochrome c-1

multiple interactions

geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CYC1 protein]

NCBI chr 7:109,947,750...109,950,142
Ensembl chr 7:108,067,115...108,069,479

G

cytochrome P450, family 1, subfamily a, polypeptide 1

multiple interactions
increases metabolic processing

[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol; [CYP1A1 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [CYP1A1 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily b, polypeptide 1

multiple interactions

[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol

NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 2, subfamily b, polypeptide 3

multiple interactions
increases metabolic processing

[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol; [CYP2B6 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; geraniol inhibits the reaction [CYP2B6 protein results in increased hydrolysis of Bupropion]

PMID:18611395 PMID:18824010

NCBI chr 1:90,780,468...90,859,852
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions

geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CYP2E1 protein]
[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol

PMID:18824010 PMID:26695085

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 3, subfamily a, polypeptide 9

increases metabolic processing
multiple interactions

CYP3A5 protein results in increased metabolism of geraniol
[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol; [CYP3A5 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [CYP3A5 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite

NCBI chr12:21,919,955...21,960,160
Ensembl chr12:16,806,207...16,846,422

G

DBF4-CDC7 kinase regulatory subunit

decreases expression

geraniol results in decreased expression of DBF4 mRNA

NCBI chr 4:26,631,491...26,656,080
Ensembl chr 4:25,676,634...25,701,066

G

DNA-damage inducible transcript 3

increases expression
multiple interactions

geraniol results in increased expression of DDIT3 mRNA
geraniol inhibits the reaction [Rotenone results in increased expression of DDIT3 protein]

PMID:27683099 PMID:30141137

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201

G

DEK proto-oncogene

decreases expression

geraniol results in decreased expression of DEK mRNA

NCBI chr17:17,786,989...17,809,096
Ensembl chr17:17,580,843...17,602,808

G

cyclin D binding myb-like transcription factor 1

increases expression

geraniol results in increased expression of DMTF1 mRNA

NCBI chr 4:24,909,937...24,950,786
Ensembl chr 4:24,910,534...24,950,967

G

DnaJ heat shock protein family (Hsp40) member C1

increases expression

geraniol results in increased expression of DNAJC1 mRNA

NCBI chr17:85,863,651...86,020,954
Ensembl chr17:80,955,237...81,111,988

G

down-regulator of transcription 1

decreases expression

geraniol results in decreased expression of DR1 mRNA

NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638

G

deoxythymidylate kinase

decreases expression

geraniol results in decreased expression of DTYMK mRNA

NCBI chr 9:101,762,899...101,771,733
Ensembl chr 9:94,315,552...94,324,870

G

E2F transcription factor 1

decreases expression

geraniol results in decreased expression of E2F1 mRNA

NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:143,049,478...143,075,361

G

E2F transcription factor 8

decreases expression

geraniol results in decreased expression of E2F8 mRNA; geraniol results in decreased expression of E2F8 protein

NCBI chr 1:107,701,985...107,720,538
Ensembl chr 1:98,565,717...98,584,098

G

ets homologous factor

decreases expression

geraniol results in decreased expression of EHF mRNA

NCBI chr 3:89,639,845...89,680,061
Ensembl chr 3:89,641,833...89,679,997

G

eukaryotic translation initiation factor 2 alpha kinase 3

multiple interactions

geraniol inhibits the reaction [Rotenone results in increased expression of EIF2AK3 protein]

NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911

G

eukaryotic translation initiation factor 2 subunit alpha

multiple interactions

geraniol inhibits the reaction [Rotenone results in increased expression of EIF2S1 protein]

NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:97,672,766...97,706,225

G

ELAV like RNA binding protein 2

decreases expression

geraniol results in decreased expression of ELAVL2 mRNA

NCBI chr 5:105,960,872...106,086,463
Ensembl chr 5:105,960,875...106,109,097

G

E74 like ETS transcription factor 1

increases expression

geraniol results in increased expression of ELF1 mRNA

NCBI chr15:61,354,026...61,395,762
Ensembl chr15:54,865,616...54,986,699

G

ETS transcription factor ELK4

increases expression

geraniol results in increased expression of ELK4 mRNA

NCBI chr13:46,004,145...46,027,206
Ensembl chr13:43,435,843...43,475,035

G

ELKS/RAB6-interacting/CAST family member 1

increases expression

geraniol results in increased expression of ERC1 mRNA

NCBI chr 4:154,435,936...154,727,987
Ensembl chr 4:152,767,419...153,055,639

G

endoplasmic reticulum to nucleus signaling 1

multiple interactions

geraniol inhibits the reaction [Rotenone results in increased expression of ERN1 protein]

NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029

G

extra spindle pole bodies like 1, separase

decreases expression

geraniol results in decreased expression of ESPL1 mRNA

NCBI chr 7:135,302,460...135,329,570
Ensembl chr 7:133,424,130...133,450,984

G

estrogen receptor 1

affects binding
multiple interactions

geraniol binds to ESR1 protein
geraniol inhibits the reaction [Estradiol binds to ESR1 protein]

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

affects binding
multiple interactions

geraniol binds to ESR2 protein
geraniol inhibits the reaction [Estradiol binds to ESR2 protein]

NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919

G

ETS proto-oncogene 2, transcription factor

increases expression

geraniol results in increased expression of ETS2 mRNA

NCBI chr11:48,491,057...48,507,843
Ensembl chr11:35,021,596...35,038,319

G

ETS variant transcription factor 1

decreases expression

geraniol results in decreased expression of ETV1 mRNA

NCBI chr 6:61,316,836...61,408,985
Ensembl chr 6:55,590,234...55,681,775

G

EWS RNA-binding protein 1

decreases expression

geraniol results in decreased expression of EWSR1 mRNA

NCBI chr14:84,179,413...84,208,149
Ensembl chr14:79,965,368...79,994,544

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

decreases expression

geraniol results in decreased expression of EZH2 mRNA

NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:76,624,399...76,687,362

G

fatty acid binding protein 4

increases expression

geraniol results in increased expression of FABP4 mRNA

NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:91,580,885...91,585,578

G

fatty acid desaturase 1

multiple interactions
decreases activity

[geraniol results in decreased activity of FADS1 protein] which results in decreased chemical synthesis of Arachidonic Acid; [geraniol results in decreased activity of FADS1 protein] which results in decreased metabolism of 8,11,14-Eicosatrienoic Acid

NCBI chr 1:216,252,605...216,267,618
Ensembl chr 1:206,827,765...206,842,734

G

FA complementation group G

decreases expression

geraniol results in decreased expression of FANCG mRNA

NCBI chr 5:62,027,494...62,037,202
Ensembl chr 5:57,231,685...57,240,029

G

fatty acid synthase

multiple interactions

geraniol promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of FASN mRNA]

NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261

G

F-box protein 5

decreases expression

geraniol results in decreased expression of FBXO5 mRNA

NCBI chr 1:44,601,412...44,607,781
Ensembl chr 1:42,196,068...42,202,437

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

geraniol results in increased expression of FOS mRNA

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036

G

FOS like 1, AP-1 transcription factor subunit

decreases expression

geraniol results in decreased expression of FOSL1 mRNA

NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:202,754,529...202,764,930

G

FOS like 2, AP-1 transcription factor subunit

increases expression

geraniol results in increased expression of FOSL2 mRNA

NCBI chr 6:30,017,952...30,039,269
Ensembl chr 6:24,300,956...24,320,034

G

forkhead box A2

decreases expression

geraniol results in decreased expression of FOXA2 mRNA

NCBI chr 3:155,923,305...155,927,508
Ensembl chr 3:135,470,131...135,474,326

G

forkhead box J3

increases expression

geraniol results in increased expression of FOXJ3 mRNA

NCBI chr 5:138,425,623...138,513,760
Ensembl chr 5:133,140,884...133,228,489

G

forkhead box M1

decreases expression

geraniol results in decreased expression of FOXM1 mRNA

NCBI chr 4:163,325,628...163,338,100
Ensembl chr 4:161,638,816...161,650,684

G

forkhead box O4

increases expression

geraniol results in increased expression of FOXO4 mRNA

NCBI chr X:70,425,218...70,432,120
Ensembl chr X:66,385,558...66,392,115

G

follistatin

increases expression

geraniol results in increased expression of FST mRNA

NCBI chr 2:47,856,345...47,863,670
Ensembl chr 2:46,123,439...46,130,571

G

far upstream element binding protein 1

decreases expression

geraniol results in decreased expression of FUBP1 mRNA

NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602

G

glucose-6-phosphate dehydrogenase

multiple interactions

geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of G6PD protein]
geraniol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]

PMID:23399806 PMID:28330423

NCBI chr X:157,352,364...157,372,144
Ensembl chr X:152,201,098...152,220,801

G

GATA zinc finger domain containing 1

increases expression

geraniol results in increased expression of GATAD1 mRNA

NCBI chr 4:31,462,251...31,473,827
Ensembl chr 4:30,507,538...30,519,107

G

gastrulation brain homeobox 2

decreases expression

geraniol results in decreased expression of GBX2 mRNA

NCBI chr 9:97,957,304...97,959,883
Ensembl chr 9:90,509,633...90,512,212

G

glucagon

multiple interactions
increases secretion

9-(tetrahydro-2-furyl)-adenine inhibits the reaction [geraniol results in increased secretion of GCG protein]; CNGA2 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]; GNAL mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]; OR1A1 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]; OR1G1 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]

NCBI chr 3:67,522,489...67,531,533
Ensembl chr 3:47,113,914...47,122,929

G

glial cell derived neurotrophic factor

multiple interactions

geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GDNF mRNA]; geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GDNF protein]

NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209

G

geminin, DNA replication inhibitor

decreases expression

geraniol results in decreased expression of GMNN mRNA

NCBI chr17:40,729,760...40,738,077
Ensembl chr17:40,301,808...40,310,054

G

G protein subunit alpha 15

increases response to substance
multiple interactions

GNA15 protein results in increased susceptibility to geraniol
[GNA15 protein results in increased susceptibility to geraniol] which results in increased activity of OR1A1B protein

NCBI chr 7:8,835,396...8,856,269
Ensembl chr 7:8,184,861...8,205,508

G

G protein subunit alpha L

increases response to substance
multiple interactions

GNAL protein results in increased susceptibility to geraniol
[GNAL protein results in increased susceptibility to geraniol] which results in increased activity of OR1A1B protein; GNAL mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]

PMID:15598656 PMID:29070885

NCBI chr18:62,892,257...63,032,510
Ensembl chr18:60,622,311...60,762,599

G

glutamic-oxaloacetic transaminase 1

multiple interactions

geraniol inhibits the reaction [Doxorubicin results in increased activity of GOT1 protein]

NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:242,357,306...242,380,633

G

glutamic--pyruvic transaminase

multiple interactions

geraniol inhibits the reaction [Doxorubicin results in increased activity of GPT protein]

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494

G

glutathione peroxidase 1

multiple interactions

[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of GPX1 mRNA]

NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024

G

glycogen synthase kinase 3 beta

multiple interactions

geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein]

NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646

G

glutathione-disulfide reductase

multiple interactions
decreases activity

geraniol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GSR protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GSR protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of GSR protein]
geraniol results in decreased activity of GSR protein
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased activity of GSR protein]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of GSR mRNA]; geraniol inhibits the reaction [2-Acetylaminofluorene results in decreased activity of GSR protein]; geraniol inhibits the reaction [Streptozocin affects the activity of GSR protein]

PMID:22509279 PMID:22760862 PMID:23033690 PMID:23399806 PMID:24752916 More...

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661

G

glutathione S-transferase pi 1

multiple interactions

geraniol inhibits the reaction [Diethylnitrosamine results in increased expression of GSTP1 protein]

NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226

G

general transcription factor IIB

increases expression

geraniol results in increased expression of GTF2B mRNA

NCBI chr 2:234,427,734...234,446,043
Ensembl chr 2:231,767,238...231,785,651

G

general transcription factor IIH subunit 1

increases expression

geraniol results in increased expression of GTF2H1 mRNA

NCBI chr 1:97,321,417...97,349,455
Ensembl chr 1:97,321,394...97,349,455

G

GTF2I repeat domain containing 1

increases expression

geraniol results in increased expression of GTF2IRD1 mRNA

NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040

G

general transcription factor III A

decreases expression

geraniol results in decreased expression of GTF3A mRNA

NCBI chr12:8,136,746...8,144,690
Ensembl chr12:8,136,747...8,144,690

G

general transcription factor IIIC subunit 1

increases expression

geraniol results in increased expression of GTF3C1 mRNA

NCBI chr 1:180,203,995...180,270,201
Ensembl chr 1:180,203,995...180,270,201

G

hepatitis A virus cellular receptor 1

multiple interactions

geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of HAVCR1 mRNA]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of HAVCR1 protein]

NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,119,088...31,151,698

G

hemoglobin subunit beta

multiple interactions

geraniol inhibits the reaction [Fructose promotes the reaction [Glucose binds to HBB protein]]

NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:158,120,200...158,252,012

G

HMG-box transcription factor 1

increases expression

geraniol results in increased expression of HBP1 mRNA

NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787

G

HIVEP zinc finger 1

increases expression

geraniol results in increased expression of HIVEP1 mRNA

NCBI chr17:22,585,016...22,714,517
Ensembl chr17:22,585,016...22,711,956

G

HLF transcription factor, PAR bZIP family member

decreases expression

geraniol results in decreased expression of HLF mRNA

NCBI chr10:75,651,320...75,708,979
Ensembl chr10:75,154,507...75,211,935

G

homeobox containing 1

increases expression

geraniol results in increased expression of HMBOX1 mRNA

NCBI chr15:39,067,805...39,200,633
Ensembl chr15:39,067,804...39,200,323

G

high mobility group 20 B

decreases expression

geraniol results in decreased expression of HMG20B mRNA

NCBI chr 7:8,368,934...8,373,650
Ensembl chr 7:8,368,990...8,373,640

G

high mobility group box 2

decreases expression

geraniol results in decreased expression of HMGB2 mRNA

NCBI chr16:37,721,374...37,723,950
Ensembl chr16:32,710,658...32,713,140
Ensembl chr 1:32,710,658...32,713,140

G

high mobility group box 3

decreases expression

geraniol results in decreased expression of HMGB3 mRNA

NCBI chr X:154,341,106...154,346,087
Ensembl chr X:149,296,375...149,301,292

G

3-hydroxy-3-methylglutaryl-CoA reductase

increases expression
decreases expression
affects expression
decreases activity

geraniol results in increased expression of HMGCR mRNA
geraniol results in decreased expression of HMGCR protein
geraniol affects the expression of HMGCR mRNA
geraniol results in decreased activity of HMGCR protein

PMID:12477733 PMID:15450939 PMID:16462894 PMID:23668785 PMID:24875281 More...

NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703

G

HMG-box containing 3

increases expression

geraniol results in increased expression of HMGXB3 mRNA

NCBI chr18:54,590,558...54,638,050
Ensembl chr18:54,590,560...54,638,155

G

HMG-box containing 4

decreases expression

geraniol results in decreased expression of HMGXB4 mRNA

NCBI chr19:13,364,741...13,403,563
Ensembl chr19:13,364,807...13,403,563

G

heme oxygenase 1

increases expression
multiple interactions

geraniol results in increased expression of HMOX1 mRNA
geraniol promotes the reaction [Doxorubicin results in increased expression of HMOX1 mRNA]; geraniol promotes the reaction [Doxorubicin results in increased expression of HMOX1 protein]
geraniol results in increased expression of HMOX1 protein

PMID:20713136 PMID:28334550 PMID:30806763 PMID:34343525

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079

G

heterogeneous nuclear ribonucleoprotein A/B

decreases expression

geraniol results in decreased expression of HNRNPAB mRNA

NCBI chr10:36,358,004...36,363,898
Ensembl chr10:35,857,041...35,863,344

G

homeo box A5

increases expression

geraniol results in increased expression of HOXA5 mRNA

NCBI chr 4:82,632,958...82,636,851
Ensembl chr 4:81,302,353...81,306,234

G

homeo box B13

decreases expression

geraniol results in decreased expression of HOXB13 mRNA

NCBI chr10:81,160,498...81,162,777
Ensembl chr10:81,160,498...81,162,777

G

homeo box C6

increases expression

geraniol results in increased expression of HOXC6 mRNA

NCBI chr 7:134,138,017...134,148,899
Ensembl chr 7:134,135,502...134,148,392

G

HRas proto-oncogene, GTPase

multiple interactions

[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with geraniol] affects the localization of HRAS protein

NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615

G

heat shock protein family A (Hsp70) member 2

decreases expression

geraniol results in decreased expression of HSPA2 mRNA

NCBI chr 6:100,864,172...100,866,946
Ensembl chr 6:95,128,350...95,131,287

G

5-hydroxytryptamine receptor 3A

decreases activity

geraniol results in decreased activity of HTR3A protein

NCBI chr 8:58,138,514...58,150,960
Ensembl chr 8:49,242,020...49,254,389

G

intercellular adhesion molecule 1

multiple interactions

geraniol inhibits the reaction [Dietary Fats results in increased expression of ICAM1 protein]
geraniol inhibits the reaction [Palmitic Acid results in increased expression of ICAM1 protein]
geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]

PMID:26165751 PMID:27107694

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438

G

inhibitor of DNA binding 1

increases expression

geraniol results in increased expression of ID1 mRNA

NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:141,211,267...141,212,419

G

inhibitor of DNA binding 3

increases expression

geraniol results in increased expression of ID3 mRNA

NCBI chr 5:153,656,253...153,657,860
Ensembl chr 5:148,372,762...148,374,349

G

interferon gamma

multiple interactions

geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IFNG protein]

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375

G

interleukin 10

increases expression
multiple interactions

geraniol results in increased expression of IL10 protein
geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL10 protein]

PMID:24934659 PMID:26973525

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313

G

interleukin 16

increases secretion

geraniol results in increased secretion of IL16 protein

NCBI chr 1:147,026,852...147,127,177
Ensembl chr 1:137,617,944...137,718,130

G

interleukin 17A

multiple interactions

geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein]

NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:23,144,402...23,147,889

G

interleukin 18

multiple interactions

geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]
geraniol inhibits the reaction [Doxorubicin results in increased expression of IL18 protein]

PMID:21430599 PMID:34343525

NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 1 alpha

increases expression

geraniol results in increased expression of IL1A protein

NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

multiple interactions

geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of IL1B protein]; geraniol inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]; geraniol inhibits the reaction [Fructose results in increased expression of IL1B protein]; geraniol inhibits the reaction [Fructose results in increased secretion of IL1B protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]
2-chloro-5-nitrobenzanilide inhibits the reaction [geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of IL1B protein]]; geraniol inhibits the reaction [[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of IL1B protein]; geraniol inhibits the reaction [[Pamidronate co-treated with Acetylmuramyl-Alanyl-Isoglutamine] results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[Pamidronate co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]; geraniol inhibits the reaction [ovalbumin-alum results in increased expression of and results in increased secretion of IL1B protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]
geraniol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]

PMID:20304105 PMID:21282739 PMID:21430599 PMID:23399806 PMID:25679220 More...

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 1 receptor type 2

increases expression

geraniol results in increased expression of IL1R2 mRNA

NCBI chr 9:49,879,928...49,920,374
Ensembl chr 9:42,384,433...42,424,725

G

interleukin 6

multiple interactions
increases expression

geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; geraniol inhibits the reaction [Dietary Fats results in increased expression of IL6 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]
geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL6 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]
geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 protein]; geraniol inhibits the reaction [Fructose results in increased expression of IL6 protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]
geraniol results in increased expression of IL6 mRNA

PMID:23399806 PMID:26190278 PMID:26695085 PMID:26973525 PMID:27107694 More...

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178

G

interleukin 7 receptor

increases expression

geraniol results in increased expression of IL7R mRNA

NCBI chr 2:60,179,561...60,204,937
Ensembl chr 2:58,454,217...58,477,757

G

interleukin enhancer binding factor 2

decreases expression

geraniol results in decreased expression of ILF2 mRNA

NCBI chr 2:175,952,174...175,971,191
Ensembl chr 2:175,952,186...175,971,337

G

insulin 1

increases secretion
multiple interactions

geraniol results in increased secretion of INS1 protein
geraniol inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]

PMID:28330423 PMID:29070885

NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:251,244,973...251,245,536

G

interferon regulatory factor 1

increases expression

geraniol results in increased expression of IRF1 mRNA

NCBI chr10:38,417,935...38,424,946
Ensembl chr10:37,916,670...37,924,166

G

interferon regulatory factor 6

increases expression

geraniol results in increased expression of IRF6 mRNA

NCBI chr13:107,200,876...107,220,083
Ensembl chr13:104,672,179...104,691,386

G

interferon regulatory factor 7

increases expression

geraniol results in increased expression of IRF7 mRNA

NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:196,367,361...196,370,832

G

interferon regulatory factor 9

increases expression

geraniol results in increased expression of IRF9 mRNA

NCBI chr15:33,065,422...33,071,881
Ensembl chr15:29,095,789...29,101,236

G

jumonji and AT-rich interaction domain containing 2

increases expression

geraniol results in increased expression of JARID2 mRNA

NCBI chr17:19,983,217...20,163,598
Ensembl chr17:19,777,266...19,955,690

G

jumonji domain containing 1C

increases expression

geraniol results in increased expression of JMJD1C mRNA

NCBI chr20:21,330,990...21,508,580
Ensembl chr20:21,332,147...21,463,122

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression

geraniol results in increased expression of JUN mRNA

NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656

G

JunB proto-oncogene, AP-1 transcription factor subunit

increases expression

geraniol results in increased expression of JUNB mRNA

NCBI chr19:40,081,126...40,082,910
Ensembl chr19:23,176,294...23,178,035

G

JunD proto-oncogene, AP-1 transcription factor subunit

increases expression

geraniol results in increased expression of JUND mRNA

NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,734,122...18,735,799

G

kinase insert domain receptor

decreases expression

geraniol results in decreased expression of KDR protein

NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,217,871...32,261,018

G

KH RNA binding domain containing, signal transduction associated 1

decreases expression

geraniol results in decreased expression of KHDRBS1 mRNA

NCBI chr 5:147,337,048...147,374,604
Ensembl chr 5:142,063,570...142,089,180

G

kinesin family member 11

decreases expression

geraniol results in decreased expression of KIF11 mRNA

NCBI chr 1:244,494,916...244,589,250
Ensembl chr 1:235,124,316...235,176,766

G

kinesin family member 15

decreases expression

geraniol results in decreased expression of KIF15 mRNA

NCBI chr 8:131,479,340...131,550,209
Ensembl chr 8:122,601,897...122,672,750

G

kinesin family member 22

decreases expression

geraniol results in decreased expression of KIF22 mRNA

NCBI chr 1:191,065,875...191,080,955
Ensembl chr 1:181,635,183...181,650,401

G

kinesin family member 23

decreases expression

geraniol results in decreased expression of KIF23 mRNA

NCBI chr 8:71,293,439...71,321,911
Ensembl chr 8:62,397,948...62,425,072

G

kinesin family member 2C

decreases expression

geraniol results in decreased expression of KIF2C mRNA

NCBI chr 5:135,873,925...135,899,267
Ensembl chr 5:130,637,347...130,662,637

G

KLF transcription factor 11

increases expression

geraniol results in increased expression of KLF11 mRNA

NCBI chr 6:41,285,699...41,297,548
Ensembl chr 6:41,285,842...41,297,550

G

KLF transcription factor 13

increases expression

geraniol results in increased expression of KLF13 mRNA

NCBI chr 1:126,917,671...126,948,436
Ensembl chr 1:117,503,602...117,551,227

G

KLF transcription factor 3

increases expression

geraniol results in increased expression of KLF3 mRNA

NCBI chr14:43,474,767...43,505,801
Ensembl chr14:43,474,767...43,497,209

G

KLF transcription factor 4

increases expression

geraniol results in increased expression of KLF4 mRNA

NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:70,278,972...70,283,602

G

KLF transcription factor 5

increases expression

geraniol results in increased expression of KLF5 mRNA

NCBI chr15:82,472,081...82,487,267
Ensembl chr15:76,064,258...76,079,445

G

KLF transcription factor 6

increases expression

geraniol results in increased expression of KLF6 mRNA

NCBI chr17:69,449,483...69,458,478
Ensembl chr17:64,531,463...64,588,570

G

KLF transcription factor 7

increases expression

geraniol results in increased expression of KLF7 mRNA

NCBI chr 9:72,927,485...73,020,167
Ensembl chr 9:65,437,167...65,526,261

G

kinetochore associated 1

decreases expression

geraniol results in decreased expression of KNTC1 mRNA

NCBI chr12:38,429,925...38,500,564
Ensembl chr12:32,769,020...32,839,561

G

KRAS proto-oncogene, GTPase

multiple interactions

geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of KRAS mRNA]

NCBI chr 4:179,916,255...179,949,613

G

low density lipoprotein receptor

increases expression

geraniol results in increased expression of LDLR mRNA

NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:20,270,041...20,294,580

G

LIF, interleukin 6 family cytokine

decreases expression

geraniol results in decreased expression of LIF protein

NCBI chr14:83,354,602...83,364,053
Ensembl chr14:79,134,574...79,140,482

G

leucine zipper transcription factor-like 1

increases expression

geraniol results in increased expression of LZTFL1 mRNA

NCBI chr 8:132,222,339...132,237,757
Ensembl chr 8:123,344,925...123,360,192

G

leucine zipper like post translational regulator 1

increases expression

geraniol results in increased expression of LZTR1 mRNA

NCBI chr11:83,487,717...83,503,896
Ensembl chr11:83,487,717...83,503,633

G

mitotic arrest deficient 2 like 1

decreases expression

geraniol results in decreased expression of MAD2L1 mRNA

NCBI chr 4:97,236,419...97,247,603
Ensembl chr 4:95,906,817...95,913,470

G

MAF bZIP transcription factor F

increases expression

geraniol results in increased expression of MAFF mRNA

NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:110,912,499...110,923,851

G

MAF bZIP transcription factor G

increases expression

geraniol results in increased expression of MAFG mRNA

NCBI chr10:106,401,633...106,410,159
Ensembl chr10:105,903,237...105,912,026

G

monoamine oxidase B

multiple interactions

geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of MAOB protein]

NCBI chr X:8,490,405...8,594,065
Ensembl chr X:5,907,266...6,011,003

G

mitogen activated protein kinase kinase 1

multiple interactions

geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MAP2K1 mRNA]

NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:64,683,449...64,755,147

G

mitogen activated protein kinase 1

multiple interactions
decreases phosphorylation

geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK1 protein]
geraniol results in decreased phosphorylation of MAPK1 protein

PMID:12388655 PMID:22760862 PMID:26154255

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

multiple interactions
decreases phosphorylation

geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK3 protein]
geraniol inhibits the reaction [Isoproterenol results in increased expression of MAPK3 mRNA]; geraniol inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]
geraniol results in decreased phosphorylation of MAPK3 protein

PMID:12388655 PMID:22760862 PMID:26154255 PMID:35608392

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863

G

mitogen-activated protein kinase 8

multiple interactions

geraniol inhibits the reaction [Isoproterenol results in increased expression of MAPK8 mRNA]; geraniol inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein]

NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981

G

minichromosome maintenance complex component 2

decreases expression

geraniol results in decreased expression of MCM2 mRNA

NCBI chr 4:122,903,679...122,918,205
Ensembl chr 4:121,346,434...121,360,847

G

myocyte enhancer factor 2a

increases expression

geraniol results in increased expression of MEF2A mRNA

NCBI chr 1:130,258,083...130,392,819
Ensembl chr 1:120,850,080...120,981,948

G

menin 1

increases expression

geraniol results in increased expression of MEN1 mRNA

NCBI chr 1:213,068,166...213,074,132
Ensembl chr 1:203,639,000...203,644,871

G

marker of proliferation Ki-67

decreases expression

geraniol results in decreased expression of MKI67 mRNA
geraniol results in decreased expression of MKI67 protein

PMID:26154255 PMID:27683099

NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:190,496,319...190,522,762

G

matrix metallopeptidase 2

multiple interactions

geraniol inhibits the reaction [Isoproterenol results in increased expression of MMP2 mRNA]

NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870

G

matrix metallopeptidase 3

increases expression

geraniol results in increased expression of MMP3 mRNA

NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:4,640,416...4,653,961

G

matrix metallopeptidase 9

multiple interactions

geraniol inhibits the reaction [Isoproterenol results in increased expression of MMP9 mRNA]

NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120

G

MAX network transcriptional repressor

increases expression

geraniol results in increased expression of MNT mRNA

NCBI chr10:59,699,208...59,714,848
Ensembl chr10:59,699,585...59,714,835

G

myeloperoxidase

multiple interactions

2-chloro-5-nitrobenzanilide inhibits the reaction [geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of MPO protein]]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of MPO protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of MPO protein]
geraniol inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of MPO protein]; geraniol inhibits the reaction [Cysteamine results in increased expression of MPO protein]; geraniol inhibits the reaction [Ethanol results in increased expression of MPO protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]

PMID:24337826 PMID:26165751 PMID:26190278 PMID:30550845

NCBI chr10:73,092,124...73,102,057
Ensembl chr10:72,594,661...72,604,819

G

mechanistic target of rapamycin kinase

decreases activity
multiple interactions

geraniol results in decreased activity of MTOR protein
geraniol inhibits the reaction [Rotenone results in increased phosphorylation of MTOR protein]

PMID:22200837 PMID:30141137

NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311

G

mevalonate kinase

multiple interactions

geraniol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]; geraniol inhibits the reaction [MVK gene mutant form results in increased susceptibility to Lipopolysaccharides]

NCBI chr12:47,802,002...47,819,503
Ensembl chr12:42,141,384...42,158,882

G

max dimerization protein 1

increases expression

geraniol results in increased expression of MXD1 mRNA

NCBI chr 4:120,654,731...120,678,972
Ensembl chr 4:119,097,353...119,117,751

G

Max dimerization protein 4

increases expression

geraniol results in increased expression of MXD4 mRNA

NCBI chr14:76,562,105...76,576,224
Ensembl chr14:76,561,774...76,576,221

G

MAX interactor 1, dimerization protein

increases expression

geraniol results in increased expression of MXI1 mRNA

NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681

G

MYB proto-oncogene, transcription factor

decreases expression

geraniol results in decreased expression of MYB mRNA

NCBI chr 1:17,759,309...17,793,306
Ensembl chr 1:15,939,761...15,973,057

G

MYB proto-oncogene like 1

decreases expression

geraniol results in decreased expression of MYBL1 mRNA

NCBI chr 5:14,365,768...14,401,012
Ensembl chr 5:9,582,934...9,618,183

G

MYB proto-oncogene like 2

decreases expression

geraniol results in decreased expression of MYBL2 mRNA

NCBI chr 3:172,124,765...172,153,221
Ensembl chr 3:151,705,288...151,733,708

G

myosin VI

increases expression

geraniol results in increased expression of MYO6 mRNA

NCBI chr 8:89,967,351...90,122,219
Ensembl chr 8:81,087,139...81,239,292

G

nuclear autoantigenic sperm protein

decreases expression

geraniol results in decreased expression of NASP mRNA

NCBI chr 5:135,294,599...135,319,992
Ensembl chr 5:130,057,363...130,082,928

G

non-SMC condensin I complex, subunit H

decreases expression

geraniol results in decreased expression of NCAPH mRNA

NCBI chr 3:134,825,271...134,852,502
Ensembl chr 3:114,371,941...114,399,180

G

nuclear receptor co-repressor 1

increases expression

geraniol results in increased expression of NCOR1 mRNA

NCBI chr10:47,498,852...47,641,612
Ensembl chr10:46,999,536...47,141,032

G

norrin cystine knot growth factor NDP

decreases expression

geraniol results in decreased expression of NDP mRNA

NCBI chr X:8,379,569...8,404,019
Ensembl chr X:5,796,487...5,820,934

G

NIMA-related kinase 2

decreases expression

geraniol results in decreased expression of NEK2 mRNA

NCBI chr13:105,936,809...105,950,054
Ensembl chr13:103,405,819...103,419,051

G

nuclear factor of activated T-cells 5

increases expression

geraniol results in increased expression of NFAT5 mRNA

NCBI chr19:52,108,982...52,196,418
Ensembl chr19:35,199,016...35,286,675

G

NFE2 like bZIP transcription factor 1

increases expression

geraniol results in increased expression of NFE2L1 mRNA

NCBI chr10:82,296,824...82,309,472
Ensembl chr10:81,800,366...81,832,318

G

NFE2 like bZIP transcription factor 2

increases expression
multiple interactions

geraniol results in increased expression of NFE2L2 mRNA
geraniol promotes the reaction [Doxorubicin results in increased expression of NFE2L2 mRNA]; geraniol promotes the reaction [Doxorubicin results in increased expression of NFE2L2 protein]
geraniol results in increased expression of NFE2L2 protein

PMID:27683099 PMID:28334550 PMID:34343525

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737

G

nuclear factor, interleukin 3 regulated

increases expression

geraniol results in increased expression of NFIL3 mRNA

NCBI chr17:12,432,376...12,447,605
Ensembl chr17:12,280,484...12,295,858

G

nuclear factor kappa B subunit 1

multiple interactions

geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of NFKB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein]

PMID:21907755 PMID:26165751

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404

G

NFKB inhibitor alpha

multiple interactions

geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of NFKBIA mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of NFKBIA protein modified form]; geraniol inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NFKBIA protein modified form]; geraniol inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]
geraniol inhibits the reaction [Doxorubicin results in increased expression of and results in increased phosphorylation of NFKBIA protein]

PMID:20506077 PMID:26190278 PMID:29050341 PMID:30550845 PMID:34343525

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941

G

nuclear transcription factor Y subunit beta

decreases expression

geraniol results in decreased expression of NFYB mRNA

NCBI chr 7:20,964,988...20,980,569
Ensembl chr 7:20,964,993...20,980,565

G

nitric oxide synthase 2

multiple interactions
decreases expression

[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of NOS2 mRNA]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of NOS2 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of NOS2 protein]; geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of NOS2 protein]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NOS2 protein]
geraniol results in decreased expression of NOS2 mRNA; geraniol results in decreased expression of NOS2 protein
geraniol inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein]

PMID:20506077 PMID:22509279 PMID:26190278 PMID:26364502 PMID:26695085 More...

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210

G

NADPH oxidase 1

multiple interactions

geraniol inhibits the reaction [Palmitic Acid results in increased expression of NOX1 protein]

NCBI chr X:101,572,338...101,625,571
Ensembl chr X:97,279,056...97,302,236

G

nucleophosmin 1

decreases expression

geraniol results in decreased expression of NPM1 mRNA

NCBI chr10:18,245,739...18,255,913
Ensembl chr10:17,739,941...17,751,645
Ensembl chr X:17,739,941...17,751,645

G

NAD(P)H quinone dehydrogenase 1

multiple interactions

geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in decreased activity of NQO1 protein]; geraniol inhibits the reaction [Doxorubicin results in decreased expression of NQO1 protein]

PMID:23499697 PMID:34343525

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557

G

nuclear receptor subfamily 1, group D, member 1

increases expression

geraniol results in increased expression of NR1D1 mRNA

NCBI chr10:84,224,599...84,231,812
Ensembl chr10:83,728,318...83,735,705

G

nuclear receptor subfamily 1, group D, member 2

increases expression

geraniol results in increased expression of NR1D2 mRNA

NCBI chr15:9,955,034...9,981,329
Ensembl chr15:7,524,257...7,550,553

G

nuclear receptor subfamily 2, group F, member 1

decreases expression

geraniol results in decreased expression of NR2F1 mRNA

NCBI chr 2:9,776,179...9,785,924
Ensembl chr 2:8,040,377...8,050,123

G

nuclear receptor subfamily 3, group C, member 1

increases expression

geraniol results in increased expression of NR3C1 mRNA

NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375

G

nuclear receptor subfamily 4, group A, member 2

increases expression

geraniol results in increased expression of NR4A2 mRNA

NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:41,689,851...41,697,877

G

nuclear receptor binding SET domain protein 2

decreases expression

geraniol results in decreased expression of NSD2 mRNA

NCBI chr14:81,057,727...81,135,866
Ensembl chr14:76,835,637...76,913,641

G

nucleolar and spindle associated protein 1

decreases expression

geraniol results in decreased expression of NUSAP1 mRNA

NCBI chr 3:127,057,220...127,092,779
Ensembl chr 3:106,603,289...106,633,624

G

ornithine decarboxylase 1

multiple interactions
decreases activity

geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 protein]
geraniol results in decreased activity of ODC1 protein

PMID:11408542 PMID:22760862

NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:40,329,964...40,336,440

G

8-oxoguanine DNA glycosylase

multiple interactions

[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of OGG1 protein]

NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:146,474,750...146,484,766

G

olfactory receptor family 1 subfamily A member 1

multiple interactions

[GNA15 protein results in increased susceptibility to geraniol] which results in increased activity of OR1A1B protein; [GNAL protein results in increased susceptibility to geraniol] which results in increased activity of OR1A1B protein; OR1A1 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]

PMID:15598656 PMID:29070885

NCBI chr10:59,557,386...59,558,324
Ensembl chr10:59,052,828...59,060,676

G

olfactory receptor family 1 subfamily AD member 5

multiple interactions

OR1G1 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]

NCBI chr10:35,808,668...35,809,579
Ensembl chr10:35,304,703...35,308,919

G

proliferation-associated 2G4

decreases expression

geraniol results in decreased expression of PA2G4 mRNA

NCBI chr 7:1,569,326...1,576,794
Ensembl chr 7:983,971...992,331

G

PBX homeobox 1

decreases expression

geraniol results in decreased expression of PBX1 mRNA

NCBI chr13:82,811,664...83,121,447
Ensembl chr13:80,278,770...80,588,594

G

proliferating cell nuclear antigen

multiple interactions
decreases expression

geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of PCNA protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of PCNA mRNA]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of PCNA protein]; geraniol inhibits the reaction [Diethylnitrosamine results in increased expression of PCNA protein]; geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein]
geraniol results in decreased expression of PCNA protein

PMID:21907755 PMID:26154255 PMID:26364502 PMID:27046949 PMID:28428697

NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:119,498,810...119,502,995

G

progesterone receptor

multiple interactions

geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PGR protein]

NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:6,072,673...6,131,344

G

prohibitin 1

decreases expression
multiple interactions

geraniol results in decreased expression of PHB1 mRNA
geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PHB1 protein]

PMID:26695085 PMID:27683099

NCBI chr10:81,102,043...81,114,815
Ensembl chr10:80,605,251...80,618,042

G

PHD finger protein 1

increases expression

geraniol results in increased expression of PHF1 mRNA

NCBI chr20:5,017,765...5,022,872
Ensembl chr20:5,017,893...5,022,871

G

PHD finger protein 21A

increases expression

geraniol results in increased expression of PHF21A mRNA

NCBI chr 3:78,158,760...78,331,903
Ensembl chr 3:78,194,549...78,331,865

G

putative homeodomain transcription factor 1

increases expression

geraniol results in increased expression of PHTF1 mRNA

NCBI chr 2:194,161,343...194,249,925
Ensembl chr 2:191,473,130...191,512,078

G

phosphoinositide-3-kinase regulatory subunit 1

multiple interactions

geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PIK3R1 mRNA]

NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:32,882,032...32,963,631

G

protein kinase, membrane associated tyrosine/threonine 1

decreases expression

geraniol results in decreased expression of PKMYT1 mRNA

NCBI chr10:13,252,805...13,263,584
Ensembl chr10:12,748,237...12,758,995

G

PLAG1 like zinc finger 1

increases expression

geraniol results in increased expression of PLAGL1 mRNA

NCBI chr 1:7,477,295...7,517,229
Ensembl chr 1:7,477,177...7,517,228

G

polo-like kinase 1

decreases expression

geraniol results in decreased expression of PLK1 mRNA

NCBI chr 1:186,147,658...186,157,637
Ensembl chr 1:176,716,420...176,726,400

G

DNA polymerase alpha 1, catalytic subunit

decreases expression

geraniol results in decreased expression of POLA1 mRNA

NCBI chr X:62,028,475...62,342,455
Ensembl chr X:58,034,619...58,348,536

G

DNA polymerase epsilon, catalytic subunit

decreases expression

geraniol results in decreased expression of POLE mRNA

NCBI chr12:52,005,155...52,053,761
Ensembl chr12:46,345,420...46,393,939

G

RNA polymerase I subunit G

decreases expression

geraniol results in decreased expression of POLR1G mRNA

NCBI chr 1:88,135,493...88,138,769
Ensembl chr 1:79,007,490...79,010,766

G

cytochrome p450 oxidoreductase

multiple interactions

geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased activity of POR protein]

NCBI chr12:26,587,674...26,655,612
Ensembl chr12:20,951,058...20,999,245

G

peroxisome proliferator activated receptor alpha

multiple interactions
increases activity

geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARA mRNA]
geraniol results in increased activity of PPARA protein

PMID:21597168 PMID:26695085

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346

G

peroxisome proliferator-activated receptor gamma

decreases expression
increases activity
multiple interactions

geraniol results in decreased expression of PPARG mRNA
geraniol results in increased activity of PPARG protein
geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in decreased expression of PPARG mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in decreased expression of PPARG protein]
geraniol inhibits the reaction [Fructose results in decreased activity of PPARG protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]

PMID:21597168 PMID:25679220 PMID:26165751 PMID:27683099 PMID:30550845

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468

G

protein regulator of cytokinesis 1

decreases expression

geraniol results in decreased expression of PRC1 mRNA

NCBI chr 1:143,659,312...143,681,019
Ensembl chr 1:134,250,081...134,271,765

G

PR/SET domain 4

increases expression

geraniol results in increased expression of PRDM4 mRNA

NCBI chr 7:19,841,560...19,868,224
Ensembl chr 7:17,954,019...17,980,489

G

peroxiredoxin 1

multiple interactions

geraniol inhibits the reaction [Isoproterenol results in decreased expression of PRDX1 mRNA]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of PRDX1 protein]

NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:130,147,204...130,162,856

G

peroxiredoxin 3

decreases expression

geraniol results in decreased expression of PRDX3 mRNA

NCBI chr 1:269,987,691...270,000,111
Ensembl chr 1:260,001,637...260,014,111

G

protein kinase AMP-activated catalytic subunit alpha 1

multiple interactions

geraniol inhibits the reaction [Rotenone results in increased expression of PRKAA1 protein]

NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:54,240,137...54,275,978

G

phosphatase and tensin homolog

multiple interactions

geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PTEN protein]

NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838

G

prostaglandin-endoperoxide synthase 2

multiple interactions

geraniol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; geraniol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of PTGS2 protein]

PMID:20506077 PMID:21597168 PMID:22760862 PMID:23399806 PMID:26190278 More...

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188

G

PTTG1 regulator of sister chromatid separation, securin

decreases expression

geraniol results in decreased expression of PTTG1 mRNA

NCBI chr10:28,394,940...28,406,410
Ensembl chr10:27,893,689...27,904,837

G

PWP1 homolog, endonuclein

decreases expression

geraniol results in decreased expression of PWP1 mRNA

NCBI chr 7:17,982,730...17,998,728
Ensembl chr 7:17,982,235...17,998,731

G

Rac GTPase-activating protein 1

decreases expression

geraniol results in decreased expression of RACGAP1 mRNA

NCBI chr 7:132,629,789...132,659,738
Ensembl chr 7:130,750,936...130,780,831

G

RAD51 recombinase

decreases expression

geraniol results in decreased expression of RAD51 mRNA

NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:106,100,381...106,125,035

G

RAD54 homolog B

decreases expression

geraniol results in decreased expression of RAD54B mRNA

NCBI chr 5:29,829,465...29,901,967
Ensembl chr 5:25,032,066...25,104,616

G

RAD54 like

decreases expression

geraniol results in decreased expression of RAD54L mRNA

NCBI chr 5:134,812,158...134,841,821
Ensembl chr 5:129,575,378...129,605,070

G

Raf-1 proto-oncogene, serine/threonine kinase

multiple interactions

geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RAF1 protein]

NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:148,679,530...148,740,317

G

regulator of calcineurin 1

increases expression

geraniol results in increased expression of RCAN1 mRNA

NCBI chr11:45,108,123...45,188,065
Ensembl chr11:31,622,210...31,702,045

G

REST corepressor 3

increases expression

geraniol results in increased expression of RCOR3 mRNA

NCBI chr13:106,156,166...106,196,542
Ensembl chr13:103,624,971...103,665,565

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of RELA mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of RELA protein modified form]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of and affects the localization of and results in increased activity of RELA protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of RELA protein modified form]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]
geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of RELA protein]; geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of and affects the localization of RELA protein]; geraniol inhibits the reaction [Doxorubicin results in increased expression of RELA protein]

PMID:23399806 PMID:26190278 PMID:26364502 PMID:28397014 PMID:29050341 More...

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484

G

regulatory factor X5

increases expression

geraniol results in increased expression of RFX5 mRNA

NCBI chr 2:182,521,191...182,528,720
Ensembl chr 2:182,521,202...182,528,717

G

ring finger protein 19A, RBR E3 ubiquitin protein ligase

increases expression

geraniol results in increased expression of RNF19A mRNA

NCBI chr 7:67,425,833...67,465,214
Ensembl chr 7:67,425,837...67,465,222

G

RuvB-like AAA ATPase 1

decreases expression

geraniol results in decreased expression of RUVBL1 mRNA

NCBI chr 4:122,489,754...122,524,666
Ensembl chr 4:120,932,417...121,029,384

G

RuvB-like AAA ATPase 2

decreases expression

geraniol results in decreased expression of RUVBL2 mRNA

NCBI chr 1:105,038,487...105,051,851
Ensembl chr 1:95,901,701...95,915,342

G

SATB homeobox 1

increases expression

geraniol results in increased expression of SATB1 mRNA

NCBI chr 9:4,916,958...5,010,359
Ensembl chr 9:4,680,920...4,753,251

G

serpin family B member 3

increases expression

geraniol results in increased expression of SERPINB3 mRNA

NCBI chr13:23,788,758...23,795,298
Ensembl chr13:23,274,484...23,313,682

G

SIM bHLH transcription factor 2

increases expression

geraniol results in increased expression of SIM2 mRNA

NCBI chr11:46,883,859...46,923,305
Ensembl chr11:33,414,218...33,453,663

G

sirtuin 1

increases expression

geraniol results in increased expression of SIRT1 mRNA

NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260

G

S-phase kinase associated protein 2

decreases expression

geraniol results in decreased expression of SKP2 mRNA

NCBI chr 2:59,888,406...59,916,471
Ensembl chr 2:58,161,229...58,189,338

G

solute carrier family 18 member A2

multiple interactions

geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC18A2 protein]

NCBI chr 1:268,399,815...268,435,229
Ensembl chr 1:258,413,959...258,448,325

G

SLC2A4 regulator

decreases expression

geraniol results in decreased expression of SLC2A4RG mRNA

NCBI chr 3:168,493,975...168,497,616

G

solute carrier family 6 member 3

multiple interactions

geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC6A3 protein]

NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413

G

SMAD family member 3

decreases expression

geraniol results in decreased expression of SMAD3 mRNA

NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:64,110,039...64,236,960

G

SMAD family member 6

decreases expression

geraniol results in decreased expression of SMAD6 mRNA

NCBI chr 8:73,345,457...73,414,985
Ensembl chr 8:64,450,114...64,519,763

G

SMAD family member 7

increases expression

geraniol results in increased expression of SMAD7 mRNA

NCBI chr18:71,263,508...71,291,849
Ensembl chr18:68,988,429...69,016,765

G

SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2

decreases expression

geraniol results in decreased expression of SMARCA2 mRNA

NCBI chr 1:233,617,277...233,784,908
Ensembl chr 1:224,191,125...224,358,684

G

SNF2 related chromatin remodeling annealing helicase 1

increases expression

geraniol results in increased expression of SMARCAL1 mRNA

NCBI chr 9:74,239,718...74,286,156
Ensembl chr 9:74,240,241...74,286,146

G

structural maintenance of chromosomes 4

decreases expression

geraniol results in decreased expression of SMC4 mRNA

NCBI chr 2:155,550,262...155,578,695
Ensembl chr 2:153,240,283...153,271,571

G

synuclein alpha

multiple interactions

geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SNCA mRNA]; geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SNCA protein]
geraniol inhibits the reaction [Rotenone results in increased expression of SNCA protein]; geraniol inhibits the reaction [SNCA protein results in decreased abundance of Dopamine]; geraniol inhibits the reaction [SNCA protein results in decreased abundance of Glutathione]; geraniol inhibits the reaction [SNCA protein results in increased abundance of Thiobarbituric Acid Reactive Substances]

PMID:24103762 PMID:27026137 PMID:30141137

NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:89,696,420...89,796,262

G

superoxide dismutase 1

multiple interactions

[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of SOD1 mRNA]
geraniol inhibits the reaction [Rotenone results in decreased activity of SOD1 protein]

PMID:22509279 PMID:30141137

NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249

G

superoxide dismutase 2

multiple interactions

[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of SOD2 mRNA]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of SOD2 protein]
geraniol inhibits the reaction [Rotenone results in decreased activity of SOD2 protein]

PMID:22509279 PMID:30141137

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189

G

SRY-box transcription factor 9

decreases expression

geraniol results in decreased expression of SOX9 mRNA

NCBI chr10:98,305,744...98,311,250
Ensembl chr10:97,806,485...97,811,994

G

SP100 nuclear antigen

increases expression

geraniol results in increased expression of SP100 mRNA

NCBI chr 9:93,758,975...93,825,068
Ensembl chr 9:86,311,032...86,377,034

G

sequestosome 1

increases expression
multiple interactions

geraniol results in increased expression of SQSTM1 mRNA
geraniol inhibits the reaction [Rotenone results in decreased expression of SQSTM1 protein]

PMID:27683099 PMID:30141137

NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673

G

sterol regulatory element binding transcription factor 1

multiple interactions

geraniol promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of SREBF1 mRNA]

NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650

G

sterol regulatory element binding transcription factor 2

increases expression

geraniol results in increased expression of SREBF2 mRNA

NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:113,663,202...113,720,848

G

signal transducer and activator of transcription 1

increases expression

geraniol results in increased expression of STAT1 mRNA

NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:49,419,340...49,588,540

G

signal transducer and activator of transcription 2

increases expression

geraniol results in increased expression of STAT2 mRNA

NCBI chr 7:1,287,025...1,302,858
Ensembl chr 7:702,495...718,967

G

signal transducer and activator of transcription 6

increases expression

geraniol results in increased expression of STAT6 mRNA

NCBI chr 7:65,365,505...65,382,825
Ensembl chr 7:63,479,642...63,498,495

G

stathmin 1

decreases expression

geraniol results in decreased expression of STMN1 mRNA

NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:146,681,436...146,687,154

G

SUB1 regulator of transcription

decreases expression

geraniol results in decreased expression of SUB1 mRNA

NCBI chr 2:62,735,379...62,747,545
Ensembl chr 2:61,005,666...61,020,436
Ensembl chr 2:61,005,666...61,020,436

G

SPT16 homolog, facilitates chromatin remodeling subunit

decreases expression

geraniol results in decreased expression of SUPT16H mRNA

NCBI chr15:27,341,196...27,378,314
Ensembl chr15:24,866,489...24,904,846

G

SPT5 homolog, DSIF elongation factor subunit

increases expression

geraniol results in increased expression of SUPT5H mRNA

NCBI chr 1:92,714,276...92,745,489
Ensembl chr 1:83,586,718...83,616,892

G

TAR DNA binding protein

decreases expression

geraniol results in decreased expression of TARDBP mRNA

NCBI chr 5:164,330,452...164,348,435
Ensembl chr 5:159,051,799...159,062,055

G

transcription elongation factor A like 1

increases expression

geraniol results in increased expression of TCEAL1 mRNA

NCBI chr X:104,850,775...104,852,724
Ensembl chr X:100,058,132...100,060,551

G

transcription factor 12

increases expression

geraniol results in increased expression of TCF12 mRNA

NCBI chr 8:72,490,447...72,799,265
Ensembl chr 8:72,492,567...72,799,201

G

TCF25 ribosome quality control complex subunit

increases expression

geraniol results in increased expression of TCF25 mRNA

NCBI chr19:51,415,341...51,449,725
Ensembl chr19:51,415,543...51,449,723

G

transcription factor 4

decreases expression

geraniol results in decreased expression of TCF4 mRNA

NCBI chr18:65,216,840...65,563,186
Ensembl chr18:62,943,782...63,284,425

G

transcription factor 7 like 2

decreases expression

geraniol results in decreased expression of TCF7L2 mRNA

NCBI chr 1:264,791,335...264,984,225
Ensembl chr 1:254,786,091...254,978,967

G

telomeric repeat binding factor 1

decreases expression

geraniol results in decreased expression of TERF1 mRNA

NCBI chr 5:8,226,345...8,255,614
Ensembl chr 5:3,443,106...3,472,340

G

transcription factor AP-2 alpha

increases expression

geraniol results in increased expression of TFAP2A mRNA

NCBI chr17:24,230,064...24,253,219
Ensembl chr17:24,024,432...24,047,507

G

transcription factor CP2

decreases expression

geraniol results in decreased expression of TFCP2 mRNA

NCBI chr 7:131,616,777...131,658,995
Ensembl chr 7:131,616,785...131,658,939

G

transcription factor Dp-1

decreases expression

geraniol results in decreased expression of TFDP1 mRNA

NCBI chr16:82,864,220...82,903,166
Ensembl chr16:76,162,043...76,200,817

G

transforming growth factor, beta 1

multiple interactions

geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TGFB1 mRNA]

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847

G

TGFB-induced factor homeobox 1

increases expression

geraniol results in increased expression of TGIF1 mRNA

NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802

G

tyrosine hydroxylase

multiple interactions

geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein]

NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:198,071,503...198,109,767

G

timeless circadian regulator

decreases expression

geraniol results in decreased expression of TIMELESS mRNA

NCBI chr 7:1,239,388...1,263,344
Ensembl chr 7:654,822...678,738

G

thymidine kinase 1

decreases expression
multiple interactions

geraniol results in decreased expression of TK1 mRNA
Fluorouracil promotes the reaction [geraniol results in decreased expression of TK1 mRNA]

NCBI chr10:103,533,449...103,544,818
Ensembl chr10:103,031,521...103,046,920

G

TLE family member 1, transcriptional corepressor

increases expression

geraniol results in increased expression of TLE1 mRNA

NCBI chr 5:90,898,182...90,982,118
Ensembl chr 5:85,851,827...85,934,774

G

toll-like receptor 4

multiple interactions

geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TLR4 mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TLR4 protein]

NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628

G

tumor necrosis factor

multiple interactions
increases expression

geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of TNF protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]
2-chloro-5-nitrobenzanilide inhibits the reaction [geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of TNF protein]]; geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of TNF protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]
geraniol results in increased expression of TNF mRNA
geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of TNF protein]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF protein]; geraniol inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; geraniol inhibits the reaction [Fructose results in increased secretion of TNF protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of TNF protein]

PMID:21430599 PMID:23399806 PMID:25679220 PMID:26190278 PMID:26695085 More...

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629

G

tumor protein p53

multiple interactions
increases expression

geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 mRNA]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 protein]
geraniol results in increased expression of TP53 mRNA

PMID:21907755 PMID:27683099

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524

G

TPX2, microtubule nucleation factor

decreases expression

geraniol results in decreased expression of TPX2 mRNA

NCBI chr 3:161,778,709...161,820,941
Ensembl chr 3:141,318,455...141,360,468

G

TRAF-interacting protein

decreases expression

geraniol results in decreased expression of TRAIP mRNA

NCBI chr 8:117,520,476...117,540,253
Ensembl chr 8:108,641,852...108,661,638

G

trafficking kinesin protein 1

increases expression

geraniol results in increased expression of TRAK1 mRNA

NCBI chr 8:129,861,967...130,016,870
Ensembl chr 8:120,984,431...121,139,367

G

tripartite motif-containing 29

increases expression

geraniol results in increased expression of TRIM29 mRNA

NCBI chr 8:43,682,221...43,706,992
Ensembl chr 8:43,682,221...43,706,992

G

transcriptional repressor GATA binding 1

increases expression

geraniol results in increased expression of TRPS1 mRNA

NCBI chr 7:83,806,121...84,032,609
Ensembl chr 7:81,921,601...82,141,905

G

transient receptor potential cation channel, subfamily V, member 1

multiple interactions

geraniol binds to and results in increased activity of TRPV1 protein

NCBI chr10:58,349,936...58,375,021
Ensembl chr10:57,851,428...57,876,513

G

TSC22 domain family, member 3

increases expression

geraniol results in increased expression of TSC22D3 mRNA

NCBI chr X:109,006,410...109,066,389
Ensembl chr X:104,217,925...104,276,861

G

Ttk protein kinase

decreases expression

geraniol results in decreased expression of TTK mRNA

NCBI chr 8:93,632,678...93,672,664
Ensembl chr 8:84,754,315...84,792,651

G

TUB like protein 3

increases expression

geraniol results in increased expression of TULP3 mRNA

NCBI chr 4:163,276,583...163,318,297
Ensembl chr 4:161,590,479...161,632,149

G

TUB like protein 4

increases expression

geraniol results in increased expression of TULP4 mRNA

NCBI chr 1:46,682,416...46,813,167
Ensembl chr 1:46,682,863...46,809,688

G

thymidylate synthetase

multiple interactions
decreases expression

Fluorouracil promotes the reaction [geraniol results in decreased expression of TYMS mRNA]

NCBI chr 9:120,760,057...120,776,149
Ensembl chr 9:113,313,452...113,329,536

G

ubiquitin-conjugating enzyme E2C

decreases expression

geraniol results in decreased expression of UBE2C mRNA

NCBI chr 3:173,925,975...173,928,375
Ensembl chr 3:153,506,636...153,513,339

G

ubiquitin-conjugating enzyme E2N

decreases expression

geraniol results in decreased expression of UBE2N mRNA

NCBI chr 7:32,041,190...32,071,252
Ensembl chr 7:30,154,616...30,184,355

G

upstream binding protein 1

decreases expression

geraniol results in decreased expression of UBP1 mRNA

NCBI chr 8:122,748,005...122,793,824
Ensembl chr 8:113,869,979...113,915,625

G

uncoupling protein 2

multiple interactions

geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of UCP2 protein]

NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:154,839,209...154,845,611

G

vascular cell adhesion molecule 1

multiple interactions

geraniol inhibits the reaction [Palmitic Acid results in increased expression of VCAM1 protein]
geraniol inhibits the reaction [Dietary Fats results in increased expression of VCAM1 protein]

NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:204,038,114...204,057,958

G

vascular endothelial growth factor A

multiple interactions

geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of VEGFA protein]

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641

G

very low density lipoprotein receptor

increases expression

geraniol results in increased expression of VLDLR mRNA

NCBI chr 1:234,239,769...234,272,150
Ensembl chr 1:224,814,377...224,845,920

G

X-box binding protein 1

increases expression

geraniol results in increased expression of XBP1 mRNA

NCBI chr14:84,604,623...84,609,707
Ensembl chr14:80,390,643...80,395,693

G

zinc finger and BTB domain containing 1

increases expression

geraniol results in increased expression of ZBTB1 mRNA

NCBI chr 6:100,832,506...100,864,019
Ensembl chr 6:95,096,387...95,118,996

G

zinc finger and BTB domain containing 10

increases expression

geraniol results in increased expression of ZBTB10 mRNA

NCBI chr 2:92,475,254...92,509,892
Ensembl chr 2:92,479,014...92,512,515

G

zinc finger and BTB domain containing 11

decreases expression

geraniol results in decreased expression of ZBTB11 mRNA

NCBI chr11:44,598,694...44,652,559
Ensembl chr11:44,616,289...44,651,050

G

zinc finger and BTB domain containing 20

increases expression

geraniol results in increased expression of ZBTB20 mRNA

NCBI chr11:70,558,010...71,297,039
Ensembl chr11:57,072,880...57,510,210

G

zinc finger protein 110

increases expression

geraniol results in increased expression of ZNF274 mRNA

NCBI chr 1:82,509,563...82,533,294
Ensembl chr 1:73,445,336...73,461,086

G

zinc finger protein 189

increases expression

geraniol results in increased expression of ZNF189 mRNA

NCBI chr 5:63,872,596...63,884,348
Ensembl chr 5:63,872,738...63,884,121

G

zinc finger protein 207

decreases expression

geraniol results in decreased expression of ZNF207 mRNA

NCBI chr10:65,883,630...65,895,895
Ensembl chr10:65,385,740...65,397,386

G

zinc finger protein 248

decreases expression

geraniol results in decreased expression of ZNF248 mRNA

NCBI chr 4:151,605,433...151,630,249
Ensembl chr 4:151,606,495...151,629,850

G

zinc finger protein 263

increases expression

geraniol results in increased expression of ZNF263 mRNA

NCBI chr10:11,764,424...11,774,324
Ensembl chr10:11,764,427...11,771,235

G

zinc finger protein 281

increases expression

geraniol results in increased expression of ZNF281 mRNA

NCBI chr13:48,096,103...48,104,265
Ensembl chr13:48,037,286...48,104,888

G

zinc finger protein 329

increases expression

geraniol results in increased expression of ZNF329 mRNA

NCBI chr 1:73,403,067...73,498,349
Ensembl chr 1:73,402,972...73,422,037

G

zinc finger protein 334

increases expression

geraniol results in increased expression of ZNF334 mRNA

NCBI chr 3:154,112,537...154,125,087
Ensembl chr 3:154,113,561...154,125,057

G

zinc finger protein 354A

increases expression

geraniol results in increased expression of ZNF354A mRNA

NCBI chr10:35,897,217...35,909,063
Ensembl chr10:35,396,231...35,408,068

G

zinc finger protein 394

increases expression

geraniol results in increased expression of ZNF394 mRNA

NCBI chr12:9,409,047...9,417,228
Ensembl chr12:9,409,078...9,417,246

G

zinc finger protein 410

increases expression

geraniol results in increased expression of ZNF410 mRNA

NCBI chr 6:103,963,265...103,990,252
Ensembl chr 6:103,964,060...103,990,225

G

zinc finger protein 455 like 1

increases expression

geraniol results in increased expression of KRBOX4 mRNA

NCBI chr 1:34,866,934...34,944,939
Ensembl chr 1:34,927,303...34,944,121

G

zinc finger protein 467

increases expression

geraniol results in increased expression of ZNF467 mRNA

NCBI chr 4:77,385,752...77,394,709
Ensembl chr 4:77,385,758...77,392,229

G

zinc finger protein 606

increases expression

geraniol results in increased expression of ZNF606 mRNA

NCBI chr 1:72,981,920...73,022,423
Ensembl chr 1:72,981,989...73,008,072

G

zinc finger protein 612

increases expression

geraniol results in increased expression of ZNF23 mRNA

NCBI chr19:54,963,400...54,976,888
Ensembl chr19:38,053,967...38,067,455

G

zinc finger protein 68

increases expression

geraniol results in increased expression of ZNF84 mRNA

NCBI chr12:16,026,058...16,040,995
Ensembl chr12:16,026,079...16,040,995

G

zinc finger protein 75D

increases expression

geraniol results in increased expression of ZNF75D mRNA

NCBI chr X:134,035,116...134,053,765
Ensembl chr X:134,036,143...134,051,519

G

zinc finger protein 768

increases expression

geraniol results in increased expression of ZNF768 mRNA

NCBI chr 1:181,966,314...181,968,950
Ensembl chr 1:181,966,316...181,969,147

G

zinc fingers and homeoboxes 2

increases expression

geraniol results in increased expression of ZHX2 mRNA

NCBI chr 7:89,226,358...89,374,266
Ensembl chr 7:89,226,463...89,374,378

G

zinc finger, MIZ-type containing 1

increases expression

geraniol results in increased expression of ZMIZ1 mRNA

NCBI chr16:1,033,983...1,239,425
Ensembl chr16:1,027,325...1,232,597

G

zinc finger MYM-type containing 4

increases expression

geraniol results in increased expression of ZMYM4 mRNA

NCBI chr 5:139,146,782...139,264,387
Ensembl chr 5:139,146,665...139,264,421

G

zinc finger, MYND-type containing 11

increases expression

geraniol results in increased expression of ZMYND11 mRNA

NCBI chr17:65,226,907...65,323,278
Ensembl chr17:60,543,077...60,631,902

G

zinc finger and SCAN domain containing 18

increases expression

geraniol results in increased expression of ZSCAN18 mRNA

NCBI chr 1:73,332,883...73,349,846
Ensembl chr 1:73,332,889...73,345,897

G

zinc finger, ZZ-type containing 3

increases expression

geraniol results in increased expression of ZZZ3 mRNA

NCBI chr 2:241,330,366...241,397,308
Ensembl chr 2:241,331,022...241,397,307

geranyl acetate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BCL2 associated X, apoptosis regulator

increases expression

geranyl acetate results in increased expression of BAX protein

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368

G

BCL2, apoptosis regulator

decreases expression

geranyl acetate results in decreased expression of BCL2 protein

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

geranyl diphosphate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

3-hydroxy-3-methylglutaryl-CoA reductase

multiple interactions
increases abundance

[geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of HMGCR protein; Lovastatin inhibits the reaction [HMGCR protein results in increased abundance of geranyl diphosphate]

PMID:19819230 PMID:19856009

NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703

G

mevalonate kinase

decreases activity
multiple interactions

geranyl diphosphate results in decreased activity of MVK protein
geranyl diphosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; geranyl diphosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]

NCBI chr12:47,802,002...47,819,503
Ensembl chr12:42,141,384...42,158,882

G

RAP1A, member of RAS oncogene family

multiple interactions

[geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of RAP1A protein modified form

NCBI chr 2:195,896,967...195,974,851
Ensembl chr 2:193,208,635...193,286,501

heptan-1-ol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

CF transmembrane conductance regulator

increases activity

Heptanol results in increased activity of CFTR protein

NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:46,560,885...46,728,756

G

gap junction protein, alpha 1

decreases phosphorylation

Heptanol results in decreased phosphorylation of GJA1 protein

NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582

hydroxycitronellal

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

C-C motif chemokine receptor 7

increases expression

hydroxycitronellal results in increased expression of CCR7 mRNA

NCBI chr10:84,594,399...84,604,514
Ensembl chr10:84,097,381...84,108,309

G

Cd80 molecule

increases expression

hydroxycitronellal results in increased expression of CD80 mRNA

NCBI chr11:75,760,073...75,798,978
Ensembl chr11:62,254,624...62,292,030

G

CD86 molecule

increases expression

hydroxycitronellal results in increased expression of CD86 protein

NCBI chr11:77,647,565...77,706,178
Ensembl chr11:64,163,828...64,200,818

G

heme oxygenase 1

increases expression

hydroxycitronellal results in increased expression of HMOX1 mRNA

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079

G

MAF bZIP transcription factor F

increases expression

hydroxycitronellal results in increased expression of MAFF mRNA

NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:110,912,499...110,923,851

G

metallothionein 1

increases expression

hydroxycitronellal results in increased expression of MT1A mRNA

NCBI chr19:10,831,959...10,832,975
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr X:10,826,032...10,827,049

G

metallothionein 2

increases expression

hydroxycitronellal results in increased expression of MT2A mRNA

NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,832,002...10,832,784

G

toll-like receptor 2

increases expression

hydroxycitronellal results in increased expression of TLR2 mRNA

NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630

G

tumor necrosis factor

increases secretion

hydroxycitronellal results in increased secretion of TNF protein

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629

G

thioredoxin 1

increases expression

hydroxycitronellal results in increased expression of TXN mRNA

NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:72,711,933...72,724,629

hydroxytyrosol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adiponectin, C1Q and collagen domain containing

decreases expression

3,4-dihydroxyphenylethanol results in decreased expression of ADIPOQ mRNA

NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564

G

AKT serine/threonine kinase 1

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein]

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921

G

BCL2 associated X, apoptosis regulator

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [Acrolein results in increased expression of BAX mRNA]; 3,4-dihydroxyphenylethanol inhibits the reaction [Acrolein results in increased expression of BAX protein]

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368

G

BCL2, apoptosis regulator

increases phosphorylation
multiple interactions

3,4-dihydroxyphenylethanol results in increased phosphorylation of BCL2 protein
3,4-dihydroxyphenylethanol inhibits the reaction [Acrolein results in decreased expression of BCL2 mRNA]; 3,4-dihydroxyphenylethanol inhibits the reaction [Acrolein results in decreased expression of BCL2 protein]

PMID:12482581 PMID:29414845

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

caspase 3

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [Acrylamide results in increased activity of CASP3 protein]
3,4-dihydroxyphenylethanol inhibits the reaction [[Xanthine co-treated with XDH protein] results in increased cleavage of CASP3 protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]; Chloroquine inhibits the reaction [3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]]

PMID:21777647 PMID:26374991 PMID:31332898

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648

G

catalase

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [Alloxan results in decreased expression of CAT protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
3,4-dihydroxyphenylethanol inhibits the reaction [Diquat results in decreased activity of CAT protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [Diquat results in decreased expression of CAT mRNA]

PMID:19393637 PMID:28225195 PMID:29497947 PMID:36572071

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478

G

C-C motif chemokine ligand 5

multiple interactions

[Vitamin E co-treated with Quercetin co-treated with kaempferol co-treated with 3,4-dihydroxyphenylethanol] results in decreased expression of CCL5 mRNA

NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377

G

cell division cycle 25A

decreases expression

3,4-dihydroxyphenylethanol results in decreased expression of CDC25A mRNA

NCBI chr 8:118,742,824...118,761,190
Ensembl chr 8:109,864,478...109,882,701

G

CCAAT/enhancer binding protein alpha

decreases expression

3,4-dihydroxyphenylethanol results in decreased expression of CEBPA mRNA

NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:87,759,433...87,762,412

G

cytochrome c oxidase subunit 4i1

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [sodium arsenite results in decreased expression of COX4 mRNA]

NCBI chr19:65,630,383...65,636,623
Ensembl chr19:48,721,199...48,727,921

G

carnitine palmitoyltransferase 1B

decreases expression

3,4-dihydroxyphenylethanol results in decreased expression of CPT1B mRNA

NCBI chr 7:122,370,974...122,380,473
Ensembl chr 7:120,491,354...120,500,404

G

colony stimulating factor 1 receptor

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased export of CSF1R protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased expression of CSF1R mRNA]

NCBI chr18:56,834,152...56,860,804
Ensembl chr18:54,546,659...54,590,415

G

DNA-damage inducible transcript 3

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [Acrolein results in increased expression of DDIT3 mRNA]; 3,4-dihydroxyphenylethanol inhibits the reaction [Acrolein results in increased expression of DDIT3 protein]

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201

G

early growth response 1

increases expression
multiple interactions

3,4-dihydroxyphenylethanol results in increased expression of EGR1 mRNA; 3,4-dihydroxyphenylethanol results in increased expression of EGR1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [3,4-dihydroxyphenylethanol results in increased expression of EGR1 mRNA]; SB 203580 promotes the reaction [3,4-dihydroxyphenylethanol results in increased expression of EGR1 mRNA]

NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766

G

fatty acid binding protein 4

decreases expression

3,4-dihydroxyphenylethanol results in decreased expression of FABP4 mRNA

NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:91,580,885...91,585,578

G

Fas-activated serine/threonine kinase

increases expression

3,4-dihydroxyphenylethanol results in increased expression of FASTK mRNA

NCBI chr 4:10,732,273...10,736,332
Ensembl chr 4:10,732,256...10,737,430

G

fibroblast growth factor 1

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in decreased expression of FGF1 mRNA]; [3,4-dihydroxyphenylethanol co-treated with Hydrogen Peroxide] results in increased expression of FGF1 mRNA; Chloroquine inhibits the reaction [3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in decreased expression of FGF1 mRNA]]

NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,686,581...30,772,357

G

growth arrest and DNA-damage-inducible, alpha

increases expression

3,4-dihydroxyphenylethanol results in increased expression of GADD45A mRNA

NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:96,154,789...96,157,115

G

glutathione peroxidase 2

multiple interactions
decreases expression

[3,4-dihydroxyphenylethanol co-treated with Diquat] results in decreased expression of GPX2 mRNA
3,4-dihydroxyphenylethanol results in decreased expression of GPX2 mRNA

NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:95,493,589...95,496,877

G

glutathione-disulfide reductase

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [Acrylamide results in increased activity of GSR protein]

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661

G

heat shock protein family A (Hsp70) member 5

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [Acrolein results in increased expression of HSPA5 mRNA]; 3,4-dihydroxyphenylethanol inhibits the reaction [Acrolein results in increased expression of HSPA5 protein]

NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891

G

heat shock protein family B (small) member 2

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [[Xanthine co-treated with XDH protein] results in decreased phosphorylation of HSPB2 protein]

NCBI chr 8:51,093,267...51,094,528
Ensembl chr 8:51,081,342...51,094,533

G

intercellular adhesion molecule 1

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438

G

interleukin 5

multiple interactions

[Vitamin E co-treated with Quercetin co-treated with kaempferol co-treated with 3,4-dihydroxyphenylethanol] results in decreased expression of IL5 mRNA

NCBI chr10:38,375,132...38,378,003
Ensembl chr10:37,874,342...37,877,213

G

interleukin 6

multiple interactions

[Vitamin E co-treated with Quercetin co-treated with kaempferol co-treated with 3,4-dihydroxyphenylethanol] results in decreased expression of IL6 mRNA
3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased export of IL6 protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]
3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in increased secretion of IL6 protein]; Chloroquine inhibits the reaction [3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in increased secretion of IL6 protein]]

PMID:16797527 PMID:31332898 PMID:34126350

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178

G

insulin 1

multiple interactions

[Glucose co-treated with 3,4-dihydroxyphenylethanol] results in increased secretion of INS1 protein

NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:251,244,973...251,245,536

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression
multiple interactions

3,4-dihydroxyphenylethanol results in increased expression of JUN mRNA; 3,4-dihydroxyphenylethanol results in increased expression of JUN protein; 3,4-dihydroxyphenylethanol results in increased expression of JUN protein modified form
3,4-dihydroxyphenylethanol promotes the reaction [[Xanthine co-treated with XDH protein] results in decreased phosphorylation of JUN protein]

PMID:12482581 PMID:26374991

NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656

G

mitogen activated protein kinase 1

increases expression
multiple interactions

3,4-dihydroxyphenylethanol results in increased expression of MAPK1 protein modified form
3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]

PMID:12482581 PMID:34126350

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

increases expression
multiple interactions

3,4-dihydroxyphenylethanol results in increased expression of MAPK3 protein modified form
3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]

PMID:12482581 PMID:34126350

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863

G

MAPK activated protein kinase 2

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [[Xanthine co-treated with XDH protein] results in increased phosphorylation of MAPKAPK2 protein]

NCBI chr13:45,066,027...45,112,326
Ensembl chr13:42,513,762...42,560,457

G

matrix metallopeptidase 9

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]

NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120

G

mitochondrially encoded cytochrome c oxidase I

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [sodium arsenite results in decreased expression of COX1 mRNA]

NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [sodium arsenite results in decreased expression of ND1 mRNA]

NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [sodium arsenite results in decreased expression of ND2 mRNA]

NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942

G

NFE2 like bZIP transcription factor 1

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [Acrolein results in decreased expression of NFE2L1 mRNA]; 3,4-dihydroxyphenylethanol inhibits the reaction [Acrolein results in decreased expression of NFE2L1 protein]

NCBI chr10:82,296,824...82,309,472
Ensembl chr10:81,800,366...81,832,318

G

peroxisome proliferator activated receptor alpha

decreases expression

3,4-dihydroxyphenylethanol results in decreased expression of PPARA mRNA

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346

G

peroxisome proliferator-activated receptor gamma

decreases expression

3,4-dihydroxyphenylethanol results in decreased expression of PPARG mRNA

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468

G

prostaglandin-endoperoxide synthase 2

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; 3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188

G

RAB2A, member RAS oncogene family

increases expression

3,4-dihydroxyphenylethanol results in increased expression of RAB2A mRNA

NCBI chr 5:26,473,424...26,537,441
Ensembl chr 5:21,676,129...21,739,899

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein]

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484

G

replication protein A3

multiple interactions

[Vitamin E co-treated with Quercetin co-treated with kaempferol co-treated with 3,4-dihydroxyphenylethanol] results in increased expression of RPA3 mRNA

NCBI chr 4:37,270,966...37,273,997
Ensembl chr 4:36,304,651...36,307,709

G

selectin E

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [Lipopolysaccharides results in increased expression of SELE protein]

NCBI chr13:78,935,997...78,945,905
Ensembl chr13:76,403,304...76,412,741

G

superoxide dismutase 2

increases activity
multiple interactions

3,4-dihydroxyphenylethanol results in increased activity of SOD2 protein
3,4-dihydroxyphenylethanol inhibits the reaction [sodium arsenite results in decreased expression of and results in decreased activity of SOD2 protein]

PMID:21384152 PMID:28225195

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189

G

signal transducer and activator of transcription 2

multiple interactions

[Vitamin E co-treated with Quercetin co-treated with kaempferol co-treated with 3,4-dihydroxyphenylethanol] results in decreased expression of STAT2 mRNA

NCBI chr 7:1,287,025...1,302,858
Ensembl chr 7:702,495...718,967

G

transcription factor A, mitochondrial

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [Acrolein results in decreased expression of TFAM mRNA]

NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,356,197...17,368,292

G

tumor necrosis factor

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; 3,4-dihydroxyphenylethanol promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; 3,4-dihydroxyphenylethanol promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Colforsin inhibits the reaction [3,4-dihydroxyphenylethanol promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; Dinoprostone inhibits the reaction [3,4-dihydroxyphenylethanol promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; Dinoprostone inhibits the reaction [3,4-dihydroxyphenylethanol promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]
3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased export of CSF1R protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased export of IL6 protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased expression of CSF1R mRNA]; 3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; 3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]
3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in increased secretion of TNF protein]; Chloroquine inhibits the reaction [3,4-dihydroxyphenylethanol inhibits the reaction [Hydrogen Peroxide results in increased secretion of TNF protein]]

PMID:12615669 PMID:17586618 PMID:25866079 PMID:31332898 PMID:34126350

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629

G

uncoupling protein 2

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [sodium arsenite results in decreased expression of UCP2 mRNA]

NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:154,839,209...154,845,611

G

vascular cell adhesion molecule 1

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [Homocysteine results in increased expression of VCAM1 protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 mRNA]; 3,4-dihydroxyphenylethanol inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]

PMID:12615669 PMID:17586618

NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:204,038,114...204,057,958

G

vascular endothelial growth factor A

multiple interactions

[3,4-dihydroxyphenylethanol co-treated with Hydrogen Peroxide] results in increased expression of VEGFA mRNA

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641

G

xanthine dehydrogenase

multiple interactions

3,4-dihydroxyphenylethanol inhibits the reaction [[Xanthine co-treated with XDH protein] results in decreased phosphorylation of HSPB2 protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [[Xanthine co-treated with XDH protein] results in increased cleavage of CASP3 protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [[Xanthine co-treated with XDH protein] results in increased phosphorylation of MAPKAPK2 protein]; 3,4-dihydroxyphenylethanol promotes the reaction [[Xanthine co-treated with XDH protein] results in decreased phosphorylation of JUN protein]

NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:21,530,113...21,592,268

linalool

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetyl-CoA carboxylase alpha

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACACA mRNA

NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,014,170...69,276,457

G

acetyl-CoA carboxylase beta

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ACACB mRNA

NCBI chr12:48,026,394...48,138,214
Ensembl chr12:42,366,548...42,457,655

G

ATP citrate lyase

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACLY mRNA

NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,412,049...85,463,320

G

aconitase 1

increases expression

linalool results in increased expression of ACO1 mRNA

NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:55,259,827...55,316,391

G

aconitase 2

increases expression

linalool results in increased expression of ACO2 mRNA

NCBI chr 7:115,265,816...115,308,931
Ensembl chr 7:113,385,646...113,428,261

G

acyl-CoA oxidase 1

multiple interactions
increases expression

PPARA protein promotes the reaction [linalool results in increased expression of ACOX1 protein]
linalool results in increased expression of ACOX1 mRNA; linalool results in increased expression of ACOX1 protein
PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACOX1 protein]

NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,406,197...101,431,232

G

acyl-CoA synthetase long-chain family member 1

multiple interactions
increases expression

PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACSL1 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACSL1 protein]
linalool results in increased expression of ACSL1 mRNA; linalool results in increased expression of ACSL1 protein
PPARA protein promotes the reaction [linalool results in increased expression of ACSL1 protein]

NCBI chr16:52,487,870...52,554,110
Ensembl chr16:45,755,254...45,821,541

G

actin alpha 2, smooth muscle

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACTA2 mRNA

NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554

G

aryl hydrocarbon receptor

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of AHR mRNA

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568

G

aldo-keto reductase family 1, member C2

increases expression

linalool results in increased expression of AKR1C2 mRNA

NCBI chr17:70,669,684...70,717,935
Ensembl chr17:65,759,788...65,775,764

G

AKT serine/threonine kinase 1

increases expression
multiple interactions

linalool results in increased expression of AKT1 mRNA
[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of AKT1 mRNA

PMID:19922762 PMID:38000518

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921

G

5'-aminolevulinate synthase 2

decreases expression

linalool results in decreased expression of ALAS2 mRNA

NCBI chr X:22,890,650...22,914,046
Ensembl chr X:19,463,171...19,486,519

G

aph-1 homolog B, gamma secretase subunit

decreases expression

linalool results in decreased expression of APH1B mRNA

NCBI chr 8:76,310,380...76,334,146
Ensembl chr 8:67,429,198...67,450,243

G

apolipoprotein A1

increases expression

linalool results in increased expression of APOA1 mRNA

NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:46,527,144...46,529,035

G

apolipoprotein C3

decreases expression

linalool results in decreased expression of APOC3 mRNA; linalool results in decreased expression of APOC3 protein

NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:46,531,478...46,533,583

G

androgen receptor

multiple interactions

linalool inhibits the reaction [Testosterone results in increased activity of AR protein]

NCBI chr X:67,135,317...67,304,476
Ensembl chr X:63,104,771...63,273,925

G

activating transcription factor 2

increases expression

linalool results in increased expression of ATF2 mRNA

NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:58,718,332...58,795,236

G

BCL2-antagonist/killer 1

increases expression

linalool results in increased expression of BAK1 mRNA

NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,100,480...5,109,264

G

BCL2 associated X, apoptosis regulator

increases expression

linalool results in increased expression of BAX mRNA

PMID:26703569 PMID:28567457

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368

G

BCL2, apoptosis regulator

decreases expression

linalool results in decreased expression of BCL2 mRNA

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 1

decreases expression

linalool results in decreased expression of BCL2L1 mRNA

NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479

G

baculoviral IAP repeat-containing 2

increases expression

linalool results in increased expression of BIRC2 mRNA

NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:4,968,842...4,988,732

G

baculoviral IAP repeat-containing 3

increases expression

linalool results in increased expression of BIRC3 mRNA

NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:5,000,845...5,015,802

G

caspase 3

increases expression
increases activity

linalool results in increased expression of CASP3 mRNA
linalool results in increased activity of CASP3 protein

PMID:26703569 PMID:28567457

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648

G

caspase 8

increases expression

linalool results in increased expression of CASP8 mRNA

NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542

G

caspase 9

increases expression
increases activity

linalool results in increased expression of CASP9 mRNA
linalool results in increased activity of CASP9 protein

PMID:26703569 PMID:28567457

Ensembl chr 5:154,109,046...154,126,626

G

catalase

multiple interactions

linalool inhibits the reaction [[Phosphates co-treated with Adenine] results in increased expression of CAT protein]; linalool inhibits the reaction [Methamphetamine results in decreased activity of CAT protein]
[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of CAT mRNA

PMID:30466616 PMID:37729970 PMID:38000518

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478

G

cellular communication network factor 2

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CTGF mRNA

NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:20,802,199...20,805,734

G

CD86 molecule

increases expression

linalool metabolite results in increased expression of CD86 protein

NCBI chr11:77,647,565...77,706,178
Ensembl chr11:64,163,828...64,200,818

G

cadherin 1

increases expression

linalool results in increased expression of CDH1 mRNA

NCBI chr19:51,402,178...51,471,572
Ensembl chr19:34,492,371...34,561,775

G

cyclin-dependent kinase inhibitor 1A

increases expression

linalool results in increased expression of CDKN1A mRNA

PMID:19922762 PMID:26703569

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1B

increases expression

linalool results in increased expression of CDKN1B mRNA

NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982

G

cyclin-dependent kinase inhibitor 1C

increases expression

linalool results in increased expression of CDKN1C mRNA

NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:198,655,407...198,658,048

G

cyclin-dependent kinase inhibitor 2A

increases expression

linalool results in increased expression of CDKN2A mRNA

NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149

G

cyclin-dependent kinase inhibitor 2B

increases expression

linalool results in increased expression of CDKN2B mRNA

NCBI chr 5:109,123,308...109,134,906
Ensembl chr 5:104,010,680...104,019,050

G

cyclin-dependent kinase inhibitor 2C

increases expression

linalool results in increased expression of CDKN2C mRNA

NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:124,411,124...124,416,278

G

CCAAT/enhancer binding protein beta

increases expression

linalool results in increased expression of CEBPB mRNA

NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:156,397,052...156,399,473

G

CCAAT/enhancer binding protein delta

increases expression

linalool results in increased expression of CEBPD mRNA

NCBI chr11:98,268,856...98,269,994
Ensembl chr11:84,764,565...84,765,829

G

collagen type X alpha 1 chain

increases expression

linalool results in increased expression of COL10A1 mRNA

NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494

G

collagen type I alpha 1 chain

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of COL1A1 mRNA

NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624

G

ceruloplasmin

multiple interactions

linalool inhibits the reaction [Methamphetamine results in decreased expression of CP protein]

NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:102,439,624...102,498,075

G

carnitine palmitoyltransferase 1A

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CPT1A mRNA

NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055

G

carnitine palmitoyltransferase 2

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CPT2 mRNA

NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:122,664,677...122,682,095

G

casein beta

increases expression

linalool results in increased expression of CSN2 mRNA

NCBI chr14:20,601,824...20,609,061
Ensembl chr14:20,322,581...20,329,817

G

cathepsin D

increases expression
multiple interactions

linalool results in increased expression of CTSD mRNA
Fulvestrant inhibits the reaction [linalool results in increased expression of CTSD mRNA]

PMID:19922762 PMID:31393563

NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:197,527,467...197,539,488

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression
multiple interactions

linalool results in increased expression of CYP1A1 mRNA
[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CYP1A1 mRNA

PMID:20491607 PMID:38000518

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 27, subfamily a, polypeptide 1

increases expression

linalool results in increased expression of CYP27A1 mRNA

NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:76,264,860...76,294,551

G

cytochrome P450, family 4, subfamily f, polypeptide 6

multiple interactions

linalool inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA]

NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782

G

diacylglycerol O-acyltransferase 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of DGAT1 mRNA

NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:108,218,524...108,234,299

G

7-dehydrocholesterol reductase

increases expression

linalool results in increased expression of DHCR7 mRNA

NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:199,015,081...199,031,055

G

DnaJ heat shock protein family (Hsp40) member B1

increases expression

linalool results in increased expression of DNAJB1 mRNA

NCBI chr19:41,427,453...41,431,141
Ensembl chr19:24,522,717...24,526,458

G

enoyl-CoA hydratase, short chain 1

increases expression

linalool results in increased expression of ECHS1 mRNA

NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:194,895,036...194,903,884

G

endothelin 1

increases expression

linalool results in increased expression of EDN1 mRNA

NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,454,420...22,460,885

G

epidermal growth factor receptor

increases expression

linalool results in increased expression of EGFR mRNA

NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382

G

ELOVL fatty acid elongase 3

decreases expression

linalool results in decreased expression of ELOVL3 mRNA

NCBI chr 1:254,938,731...254,942,559
Ensembl chr 1:244,997,287...245,001,115

G

estrogen receptor 1

increases activity

linalool results in increased activity of ESR1 protein

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002

G

coagulation factor II, thrombin

multiple interactions

linalool inhibits the reaction [Methamphetamine results in decreased expression of F2 protein]

NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:77,596,198...77,609,486

G

fatty acid binding protein 1

increases expression

linalool results in increased expression of FABP1 mRNA

NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:103,191,006...103,194,788

G

fatty acid synthase

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of FASN mRNA

NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261

G

fibronectin 1

increases expression

linalool results in increased expression of FN1 mRNA

NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:73,196,044...73,264,678

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

linalool results in increased expression of FOS mRNA

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036

G

forkhead box O1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of FOXO1 mRNA

NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:136,312,168...136,387,790

G

gamma-aminobutyric acid type B receptor subunit 1

increases expression

linalool results in increased expression of GABBR1 mRNA

NCBI chr20:1,469,779...1,499,352
Ensembl chr20:1,464,534...1,493,994

G

growth arrest and DNA-damage-inducible, alpha

increases expression

linalool results in increased expression of GADD45A mRNA; linalool results in increased expression of GADD45A protein

NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:96,154,789...96,157,115

G

glutamate-cysteine ligase, catalytic subunit

increases expression

linalool results in increased expression of GCLC mRNA

NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544

G

glutathione peroxidase 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of GPX1 mRNA

NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024

G

growth regulating estrogen receptor binding 1

multiple interactions
increases expression

Fulvestrant inhibits the reaction [linalool results in increased expression of GREB1 mRNA]

NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633

G

glutathione-disulfide reductase

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of GSR mRNA

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661

G

hemoglobin subunit beta

decreases expression

linalool results in decreased expression of HBB mRNA

NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:158,120,200...158,252,012

G

3-hydroxy-3-methylglutaryl-CoA reductase

multiple interactions
decreases expression

linalool inhibits the reaction [KAT2B protein binds to HMGCR promoter]; linalool inhibits the reaction [SREBF2 protein binds to HMGCR promoter]; linalool results in decreased expression of and results in increased ubiquitination of HMGCR protein
linalool results in decreased expression of HMGCR mRNA; linalool results in decreased expression of HMGCR protein

PMID:21944868 PMID:24613879

NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703

G

heme oxygenase 1

increases expression

linalool metabolite results in increased expression of HMOX1 mRNA

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079

G

homer scaffold protein 1

increases expression

linalool results in increased expression of HOMER1 mRNA

NCBI chr 2:26,279,012...26,388,279
Ensembl chr 2:24,543,093...24,644,785

G

heat shock transcription factor 1

increases expression

linalool results in increased expression of HSF1 mRNA

NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:108,196,056...108,223,011

G

heat shock protein 90 alpha family class A member 1

increases expression

linalool results in increased expression of HSP90AA1 mRNA

NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:129,702,383...129,707,268

G

heat shock protein family A (Hsp70) member 1 like

increases expression

linalool results in increased expression of HSPA1L mRNA

NCBI chr20:3,853,496...3,860,223
Ensembl chr20:3,848,843...3,855,571

G

heat shock protein family A (Hsp70) member 4

increases expression

linalool results in increased expression of HSPA4 mRNA

NCBI chr10:37,908,866...37,951,994
Ensembl chr10:37,408,025...37,449,001

G

heat shock protein family B (small) member 1

increases expression

linalool results in increased expression of HSPB1 mRNA

NCBI chr12:26,430,640...26,432,301
Ensembl chr12:20,794,028...20,795,743

G

heat shock protein family B (small) member 2

increases expression

linalool results in increased expression of HSPB2 mRNA

NCBI chr 8:51,093,267...51,094,528
Ensembl chr 8:51,081,342...51,094,533

G

heat shock protein family H (Hsp110) member 1

increases expression

linalool results in increased expression of HSPH1 mRNA

NCBI chr12:10,427,368...10,446,602
Ensembl chr12:5,390,922...5,410,224

G

intercellular adhesion molecule 1

increases expression
multiple interactions

linalool metabolite results in increased expression of ICAM1 protein
linalool inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]

PMID:29029310 PMID:29276222

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438

G

inhibitor of DNA binding 2

increases expression

linalool results in increased expression of ID2 mRNA

NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:41,728,946...41,744,400

G

interleukin 10

multiple interactions

linalool inhibits the reaction [Methamphetamine results in decreased expression of IL10 protein]

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313

G

interleukin 1 beta

multiple interactions

linalool inhibits the reaction [Methamphetamine results in increased expression of IL1B protein]

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

multiple interactions

linalool inhibits the reaction [Methamphetamine results in increased expression of IL6 protein]

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178

G

insulin induced gene 1

increases expression

linalool results in increased expression of INSIG1 protein

NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:7,315,495...7,323,952

G

insulin induced gene 2

increases expression

linalool results in increased expression of INSIG2 mRNA

NCBI chr13:35,025,160...35,052,937
Ensembl chr13:32,473,742...32,494,923

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression

linalool results in increased expression of JUN protein

NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656

G

lysine acetyltransferase 2B

multiple interactions

linalool inhibits the reaction [KAT2B protein binds to HMGCR promoter]

NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,562,288...6,667,064

G

lipase A, lysosomal acid type

increases expression

linalool results in increased expression of LIPA mRNA

NCBI chr 1:241,437,524...241,470,936
Ensembl chr 1:232,024,356...232,057,633

G

lipoprotein lipase

increases expression
multiple interactions

linalool results in increased expression of LPL mRNA; linalool results in increased expression of LPL protein
PPARA gene mutant form inhibits the reaction [linalool results in increased expression of LPL mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of LPL protein]
PPARA protein promotes the reaction [linalool results in increased expression of LPL protein]

NCBI chr16:25,596,205...25,621,928
Ensembl chr16:20,829,465...20,855,249

G

mitogen activated protein kinase 1

increases phosphorylation

linalool metabolite results in increased phosphorylation of MAPK1 protein

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

increases phosphorylation

linalool metabolite results in increased phosphorylation of MAPK3 protein

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863

G

myristoylated alanine rich protein kinase C substrate

increases expression

linalool results in increased expression of MARCKS mRNA

NCBI chr20:42,240,185...42,245,882
Ensembl chr20:40,685,315...40,691,012

G

methylmalonyl CoA epimerase

decreases expression

linalool results in decreased expression of MCEE mRNA

NCBI chr 1:117,964,576...117,987,779
Ensembl chr 1:117,964,576...117,988,484

G

malate dehydrogenase 2

increases expression

linalool results in increased expression of MDH mRNA

NCBI chr12:26,530,886...26,543,841
Ensembl chr12:20,894,262...20,907,271

G

MDM2 proto-oncogene

increases expression

linalool results in increased expression of MDM2 mRNA

NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:53,290,664...53,314,915

G

malonyl-CoA decarboxylase

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of MLYCD mRNA

NCBI chr19:64,356,582...64,372,447
Ensembl chr19:47,447,970...47,463,793

G

matrix metallopeptidase 9

increases expression

linalool results in increased expression of MMP9 mRNA

NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120

G

myelin protein zero

decreases expression

linalool results in decreased expression of MPZ mRNA

NCBI chr13:86,103,290...86,109,156
Ensembl chr13:83,570,811...83,576,679

G

MYC proto-oncogene, bHLH transcription factor

increases expression

linalool results in increased expression of MYC mRNA

NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630

G

NFE2 like bZIP transcription factor 2

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of NFE2L2 mRNA; linalool metabolite results in increased expression of and results in increased activity of NFE2L2 protein

PMID:29029310 PMID:38000518

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737

G

nuclear factor kappa B subunit 1

increases expression
multiple interactions

linalool results in increased expression of NFKB1 mRNA
[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of NFKB1 mRNA

PMID:19922762 PMID:38000518

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404

G

neuropeptide Y

increases expression

linalool results in increased expression of NPY mRNA
linalool results in increased expression of NPY protein

NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:78,881,264...78,888,495

G

NAD(P)H quinone dehydrogenase 1

increases expression

linalool metabolite results in increased expression of NQO1 mRNA

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557

G

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

increases expression

linalool results in increased expression of PCK2 mRNA

NCBI chr15:32,997,853...33,006,691
Ensembl chr15:29,027,894...29,037,283

G

phosphoglucomutase 1

increases expression

linalool results in increased expression of PGM1 mRNA

NCBI chr 5:119,710,734...119,770,159
Ensembl chr 5:114,595,293...114,654,728

G

progesterone receptor

multiple interactions
increases expression

Fulvestrant inhibits the reaction [linalool results in increased expression of PGR mRNA]

NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:6,072,673...6,131,344

G

PHD finger protein 1

decreases expression

linalool results in decreased expression of PHF1 mRNA

NCBI chr20:5,017,765...5,022,872
Ensembl chr20:5,017,893...5,022,871

G

peroxisome proliferator activated receptor alpha

increases expression
increases response to substance
decreases response to substance
multiple interactions

linalool results in increased expression of PPARA mRNA; linalool results in increased expression of PPARA protein
PPARA protein results in increased susceptibility to linalool
PPARA gene mutant form results in decreased susceptibility to linalool
[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of PPARA mRNA; linalool binds to and results in increased activity of PPARA protein; PPARA protein promotes the reaction [linalool results in increased expression of ACOX1 protein]; PPARA protein promotes the reaction [linalool results in increased expression of ACSL1 protein]; PPARA protein promotes the reaction [linalool results in increased expression of LPL protein]; PPARA protein promotes the reaction [linalool results in increased expression of SLC27A4 protein]; PPARA protein promotes the reaction [linalool results in increased expression of UCP2 protein]
PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACOX1 protein]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACSL1 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACSL1 protein]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of LPL mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of LPL protein]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of SLC27A4 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of SLC27A4 protein]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of UCP2 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of UCP2 protein]

PMID:24752549 PMID:38000518

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346

G

proteasome 26S subunit, non-ATPase 9

increases expression

linalool results in increased expression of PSMD9 mRNA

NCBI chr12:38,998,027...39,018,340

G

prostaglandin-endoperoxide synthase 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of PTGS1 mRNA

NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:19,584,015...19,605,586

G

peroxisomal membrane protein 4

decreases expression

linalool results in decreased expression of PXMP4 mRNA

NCBI chr 3:163,553,582...163,570,829
Ensembl chr 3:143,093,018...143,110,651

G

regulator of G-protein signaling 5

increases expression

linalool results in increased expression of RGS5 mRNA

NCBI chr13:84,381,077...84,417,875
Ensembl chr13:81,836,304...81,885,518

G

RUNX family transcription factor 2

multiple interactions

linalool inhibits the reaction [[Phosphates co-treated with Adenine] results in increased expression of RUNX2 mRNA]

NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:16,167,482...16,492,167

G

RUS family member 1

increases expression

linalool results in increased expression of RUSF1 mRNA

NCBI chr 1:182,852,257...182,881,652
Ensembl chr 1:182,852,262...182,880,732

G

RuvB-like AAA ATPase 2

decreases expression

linalool results in decreased expression of RUVBL2 mRNA

NCBI chr 1:105,038,487...105,051,851
Ensembl chr 1:95,901,701...95,915,342

G

S100 calcium binding protein A9

decreases expression

linalool results in decreased expression of S100A9 mRNA

NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:176,190,361...176,193,230

G

SEC14-like lipid binding 2

multiple interactions

linalool inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA]

NCBI chr14:83,197,384...83,222,059
Ensembl chr14:78,973,808...78,993,788

G

selectin E

multiple interactions

linalool inhibits the reaction [TNF protein results in increased expression of SELE mRNA]

NCBI chr13:78,935,997...78,945,905
Ensembl chr13:76,403,304...76,412,741

G

sirtuin 3

decreases expression
multiple interactions

linalool results in decreased expression of SIRT3 mRNA; linalool results in decreased expression of SIRT3 protein
linalool inhibits the reaction [SOD2 protein binds to SIRT3 protein]

NCBI chr 1:205,371,703...205,394,145
Ensembl chr 1:195,942,073...195,964,808

G

solute carrier family 20 member 1

multiple interactions

linalool inhibits the reaction [[Phosphates co-treated with Adenine] results in increased expression of SLC20A1 mRNA]

NCBI chr 3:136,880,360...136,894,255
Ensembl chr 3:116,427,098...116,441,051

G

solute carrier family 27 member 4

multiple interactions
increases expression

PPARA gene mutant form inhibits the reaction [linalool results in increased expression of SLC27A4 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of SLC27A4 protein]
linalool results in increased expression of SLC27A4 mRNA; linalool results in increased expression of SLC27A4 protein
PPARA protein promotes the reaction [linalool results in increased expression of SLC27A4 protein]

NCBI chr 3:33,472,903...33,485,824
Ensembl chr 3:13,075,022...13,087,943

G

solute carrier family 6 member 3

decreases expression

linalool results in decreased expression of SLC6A3 mRNA

NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413

G

snail family transcriptional repressor 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of SNAI1 mRNA

NCBI chr 3:176,667,476...176,671,965
Ensembl chr 3:156,248,485...156,252,969

G

superoxide dismutase 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of SOD1 mRNA

NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249

G

superoxide dismutase 2

multiple interactions

linalool inhibits the reaction [SOD2 protein binds to SIRT3 protein]; linalool results in decreased activity of and results in increased acetylation of SOD2 protein

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189

G

SRY-box transcription factor 11

increases expression

linalool results in increased expression of SOX11 mRNA

NCBI chr 6:49,736,773...49,738,794
Ensembl chr 6:44,008,340...44,010,354

G

secreted phosphoprotein 1

multiple interactions

linalool inhibits the reaction [[Phosphates co-treated with Adenine] results in increased expression of SPP1 mRNA]

NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,308,885...5,315,162

G

squalene epoxidase

increases expression

linalool results in increased expression of SQLE mRNA

NCBI chr 7:92,758,175...92,773,049
Ensembl chr 7:90,868,011...90,883,618

G

sterol regulatory element binding transcription factor 2

multiple interactions
decreases expression

linalool inhibits the reaction [SREBF2 protein binds to HMGCR promoter]
linalool results in decreased expression of SREBF2 mRNA; linalool results in decreased expression of SREBF2 protein

NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:113,663,202...113,720,848

G

transforming growth factor, beta 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of TGFB1 mRNA

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847

G

tyrosine hydroxylase

decreases expression

linalool results in decreased expression of TH mRNA

NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:198,071,503...198,109,767

G

tumor necrosis factor

multiple interactions

linalool inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; linalool inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; linalool inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]
linalool inhibits the reaction [Methamphetamine results in increased expression of TNF protein]

PMID:29276222 PMID:37729970

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629

G

tumor protein p53

increases expression
increases response to substance

linalool results in increased expression of TP53 mRNA; linalool results in increased expression of TP53 protein
TP53 results in increased susceptibility to linalool

PMID:19922762 PMID:26703569

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524

G

transient receptor potential cation channel, subfamily A, member 1

increases activity

linalool results in increased activity of TRPA1 protein

NCBI chr 5:9,163,060...9,217,325
Ensembl chr 5:4,379,999...4,433,570

G

thyroid stimulating hormone subunit beta

decreases expression

linalool results in decreased expression of TSHB mRNA

NCBI chr 2:192,913,171...192,918,054
Ensembl chr 2:190,224,676...190,229,559

G

thioredoxin 1

increases expression

linalool results in increased expression of TXN mRNA

NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:72,711,933...72,724,629

G

uncoupling protein 2

multiple interactions
increases expression

PPARA protein promotes the reaction [linalool results in increased expression of UCP2 protein]
PPARA gene mutant form inhibits the reaction [linalool results in increased expression of UCP2 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of UCP2 protein]
linalool results in increased expression of UCP2 mRNA; linalool results in increased expression of UCP2 protein

NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:154,839,209...154,845,611

G

UDP glucuronosyltransferase family 2 member B15

increases metabolic processing

UGT2B15 protein results in increased metabolism of linalool

NCBI chr14:21,122,866...21,138,450
Ensembl chr14:20,768,015...20,783,589

G

UDP glucuronosyltransferase 2 family, polypeptide B34 like 1

multiple interactions

linalool inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA]

NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704

G

vascular cell adhesion molecule 1

multiple interactions

linalool inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]

NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:204,038,114...204,057,958

G

ischemia related factor vof-16

increases expression

linalool results in increased expression of VOF16 mRNA

NCBI chr 8:41,953,062...41,955,169

G

Wnt family member 1

increases expression

linalool results in increased expression of WNT1 mRNA

NCBI chr 7:131,817,558...131,821,605
Ensembl chr 7:129,938,604...129,942,651

G

WD repeat and SOCS box-containing 1

increases expression

linalool results in increased expression of WSB1 mRNA

NCBI chr10:64,202,761...64,219,039
Ensembl chr10:64,202,763...64,219,019

G

zinc finger E-box binding homeobox 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ZEB1 mRNA

NCBI chr17:56,644,397...56,811,155
Ensembl chr17:51,948,948...52,115,214

G

zinc finger E-box binding homeobox 2

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ZEB2 mRNA

NCBI chr 3:49,624,028...49,754,323
Ensembl chr 3:29,218,301...29,345,157

linalyl acetate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetyl-CoA carboxylase alpha

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACACA mRNA

NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,014,170...69,276,457

G

acetyl-CoA carboxylase beta

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ACACB mRNA

NCBI chr12:48,026,394...48,138,214
Ensembl chr12:42,366,548...42,457,655

G

ATP citrate lyase

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACLY mRNA

NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,412,049...85,463,320

G

actin alpha 2, smooth muscle

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACTA2 mRNA

NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554

G

aryl hydrocarbon receptor

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of AHR mRNA

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568

G

AKT serine/threonine kinase 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of AKT1 mRNA

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921

G

androgen receptor

multiple interactions

linalyl acetate inhibits the reaction [Testosterone results in increased activity of AR protein]

NCBI chr X:67,135,317...67,304,476
Ensembl chr X:63,104,771...63,273,925

G

catalase

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of CAT mRNA

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478

G

cellular communication network factor 2

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CTGF mRNA

NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:20,802,199...20,805,734

G

collagen type I alpha 1 chain

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of COL1A1 mRNA

NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624

G

carnitine palmitoyltransferase 1A

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CPT1A mRNA

NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055

G

carnitine palmitoyltransferase 2

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CPT2 mRNA

NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:122,664,677...122,682,095

G

cathepsin D

increases expression
multiple interactions

linalyl acetate results in increased expression of CTSD mRNA
Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of CTSD mRNA]

NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:197,527,467...197,539,488

G

cytochrome P450, family 1, subfamily a, polypeptide 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CYP1A1 mRNA

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 4, subfamily f, polypeptide 6

multiple interactions

linalyl acetate inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA]

NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782

G

diacylglycerol O-acyltransferase 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of DGAT1 mRNA

NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:108,218,524...108,234,299

G

estrogen receptor 1

multiple interactions
increases activity

NCOA2 protein promotes the reaction [linalyl acetate results in increased activity of ESR1 protein]

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002

G

fatty acid synthase

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of FASN mRNA

NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261

G

forkhead box O1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of FOXO1 mRNA

NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:136,312,168...136,387,790

G

glutathione peroxidase 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of GPX1 mRNA

NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024

G

growth regulating estrogen receptor binding 1

multiple interactions
increases expression

Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of GREB1 mRNA]

NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633

G

glutathione-disulfide reductase

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of GSR mRNA

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661

G

intercellular adhesion molecule 1

multiple interactions

linalyl acetate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438

G

malonyl-CoA decarboxylase

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of MLYCD mRNA

NCBI chr19:64,356,582...64,372,447
Ensembl chr19:47,447,970...47,463,793

G

nuclear receptor coactivator 2

multiple interactions

NCOA2 protein promotes the reaction [linalyl acetate results in increased activity of ESR1 protein]

NCBI chr 5:10,618,712...10,852,776
Ensembl chr 5:5,835,706...6,067,451

G

NFE2 like bZIP transcription factor 2

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of NFE2L2 mRNA

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737

G

nuclear factor kappa B subunit 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of NFKB1 mRNA

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404

G

progesterone receptor

multiple interactions
increases expression

Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of PGR mRNA]

NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:6,072,673...6,131,344

G

peroxisome proliferator activated receptor alpha

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of PPARA mRNA

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346

G

prostaglandin-endoperoxide synthase 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of PTGS1 mRNA

NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:19,584,015...19,605,586

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

linalyl acetate inhibits the reaction [TNF protein results in increased expression of and affects the localization of RELA protein modified form]

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484

G

SEC14-like lipid binding 2

multiple interactions

linalyl acetate inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA]

NCBI chr14:83,197,384...83,222,059
Ensembl chr14:78,973,808...78,993,788

G

selectin E

multiple interactions

linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELE mRNA]

NCBI chr13:78,935,997...78,945,905
Ensembl chr13:76,403,304...76,412,741

G

selectin P

multiple interactions

linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELP mRNA]

NCBI chr13:79,009,379...79,044,994
Ensembl chr13:76,476,295...76,511,845

G

snail family transcriptional repressor 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of SNAI1 mRNA

NCBI chr 3:176,667,476...176,671,965
Ensembl chr 3:156,248,485...156,252,969

G

superoxide dismutase 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of SOD1 mRNA

NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249

G

transforming growth factor, beta 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of TGFB1 mRNA

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847

G

tumor necrosis factor

multiple interactions

linalyl acetate inhibits the reaction [TNF protein results in increased expression of and affects the localization of RELA protein modified form]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELP mRNA]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629

G

UDP glucuronosyltransferase 2 family, polypeptide B34 like 1

multiple interactions

linalyl acetate inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA]

NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704

G

vascular cell adhesion molecule 1

multiple interactions

linalyl acetate inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]

NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:204,038,114...204,057,958

G

zinc finger E-box binding homeobox 1

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ZEB1 mRNA

NCBI chr17:56,644,397...56,811,155
Ensembl chr17:51,948,948...52,115,214

G

zinc finger E-box binding homeobox 2

multiple interactions

[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ZEB2 mRNA

NCBI chr 3:49,624,028...49,754,323
Ensembl chr 3:29,218,301...29,345,157

mephedrone

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

caspase 3

increases activity

mephedrone results in increased activity of CASP3 protein

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648

G

catalase

decreases expression
increases expression

mephedrone results in decreased expression of CAT protein
mephedrone results in increased expression of CAT protein

PMID:25817894 PMID:26747301

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478

G

C-C motif chemokine ligand 2

affects expression

mephedrone affects the expression of CCL2 protein

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226

G

dopamine receptor D2

decreases expression

mephedrone results in decreased expression of DRD2 protein

NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875

G

glutathione peroxidase 1

decreases expression
increases expression

mephedrone results in decreased expression of GPX1 protein
mephedrone results in increased expression of GPX1 protein

PMID:25817894 PMID:26747301

NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024

G

interleukin 1 alpha

affects expression

mephedrone affects the expression of IL1A protein

NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

affects expression

mephedrone affects the expression of IL1B protein

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

affects expression

mephedrone affects the expression of IL6 protein

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178

G

nitric oxide synthase 1

affects expression

mephedrone affects the expression of NOS1 protein

NCBI chr12:44,276,011...44,456,371
Ensembl chr12:38,626,714...38,710,945

G

solute carrier family 6 member 3

decreases expression
multiple interactions

mephedrone results in decreased expression of SLC6A3 protein
Ethanol promotes the reaction [mephedrone results in decreased expression of SLC6A3 protein]

PMID:25817894 PMID:26747301

NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413

G

solute carrier family 6 member 4

multiple interactions
decreases expression

Ethanol promotes the reaction [mephedrone results in decreased expression of SLC6A4 protein]

PMID:25817894 PMID:26747301

NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384

G

superoxide dismutase 1

affects expression

mephedrone affects the expression of SOD1 protein

NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249

G

tyrosine hydroxylase

multiple interactions
decreases expression

Ethanol promotes the reaction [mephedrone results in decreased expression of TH protein]

PMID:25817894 PMID:26747301

NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:198,071,503...198,109,767

G

tumor necrosis factor

affects expression

mephedrone affects the expression of TNF protein

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629

G

tryptophan hydroxylase 2

multiple interactions
decreases expression

Ethanol promotes the reaction [mephedrone results in decreased expression of TPH2 protein]

PMID:25817894 PMID:26747301

NCBI chr 7:52,571,909...52,676,305
Ensembl chr 7:50,685,694...50,789,424

monobenzyl phthalate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

actin, beta

multiple interactions

[mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono(2-ethyl-5-oxohexyl)phthalate co-treated with 2-ethyl-5-carboxypentyl phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate metabolite co-treated with monoethyl phthalate co-treated with monobutyl phthalate] results in increased expression of ACTB mRNA; [mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with methylparaben] results in increased expression of ACTB mRNA

NCBI chr12:16,776,664...16,779,634
Ensembl chr12:11,663,109...11,672,877

G

aryl hydrocarbon receptor

affects expression
multiple interactions

mono-benzyl phthalate affects the expression of AHR mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of AHR mRNA

PMID:28381288 PMID:31884101

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568

G

aryl-hydrocarbon receptor repressor

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of AHRR mRNA

NCBI chr 1:30,822,219...30,917,251
Ensembl chr 1:28,993,634...29,088,673

G

apoptosis inducing factor, mitochondria associated 1

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of AIFM1 mRNA

NCBI chr X:132,528,107...132,567,237
Ensembl chr X:127,650,226...127,689,256

G

androgen receptor

multiple interactions

mono-benzyl phthalate promotes the reaction [Dihydrotestosterone results in increased activity of AR protein]
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of AR mRNA

PMID:28571686 PMID:31884101

NCBI chr X:67,135,317...67,304,476
Ensembl chr X:63,104,771...63,273,925

G

aryl hydrocarbon receptor nuclear translocator

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of ARNT mRNA

NCBI chr 2:185,686,703...185,745,546
Ensembl chr 2:182,997,736...183,056,580

G

BCL2 associated X, apoptosis regulator

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of BAX mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of BAX mRNA

PMID:31884101 PMID:35861251

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368

G

BCL2, apoptosis regulator

multiple interactions
decreases methylation
increases expression

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of BCL2 mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of BCL2 mRNA
mono-benzyl phthalate results in decreased methylation of BCL2 promoter
mono-benzyl phthalate results in increased expression of BCL2 mRNA

PMID:31884101 PMID:35487445 PMID:35861251

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 10

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of BCL2L10 mRNA; [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate] results in increased expression of BCL2L10 mRNA

PMID:31884101 PMID:33511402

NCBI chr 8:84,987,833...84,993,878
Ensembl chr 8:76,107,326...76,113,367

G

BH3 interacting domain death agonist

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of BID mRNA

NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:154,113,198...154,134,720

G

BCL2 family apoptosis regulator BOK

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of BOK mRNA

NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:94,223,389...94,234,476

G

caspase 3

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CASP3 mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of CASP3 mRNA

PMID:31884101 PMID:35861251

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648

G

caspase 8

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CASP8 mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CASP8 mRNA

PMID:31884101 PMID:35861251

NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542

G

catalase

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CAT mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CAT mRNA

PMID:31884101 PMID:35861251

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478

G

coiled-coil domain containing 163

multiple interactions

[mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono(2-ethyl-5-oxohexyl)phthalate co-treated with 2-ethyl-5-carboxypentyl phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with monoethyl phthalate co-treated with monobutyl phthalate] affects the expression of CCDC163 mRNA

NCBI chr 5:130,172,014...130,178,934
Ensembl chr 5:130,172,774...130,178,929

G

C-C motif chemokine ligand 2

increases expression

mono-benzyl phthalate results in increased expression of CCL2 mRNA

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226

G

cyclin A2

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCNA2 mRNA

NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:119,426,089...119,433,577

G

cyclin B1

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCNB1 mRNA

NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:31,912,193...31,921,172

G

cyclin B2

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCNB2 mRNA

NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:71,087,595...71,100,874

G

cyclin D1

increases expression
decreases methylation

mono-benzyl phthalate results in increased expression of CCND1 mRNA
mono-benzyl phthalate results in decreased methylation of CCND1 promoter

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602

G

cyclin D3

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCND3 mRNA

NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:13,394,169...13,489,371

G

cyclin E1

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCNE1 mRNA

NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:90,781,949...90,791,101

G

C-C motif chemokine receptor 7

multiple interactions

[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased expression of CCR7 mRNA

NCBI chr10:84,594,399...84,604,514
Ensembl chr10:84,097,381...84,108,309

G

CD163 molecule

multiple interactions

[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in decreased expression of CD163 mRNA

NCBI chr 4:158,770,751...158,804,146
Ensembl chr 4:157,085,093...157,117,878

G

CD36 molecule

increases expression
multiple interactions

mono-benzyl phthalate results in increased expression of CD36 mRNA
GW 6471 inhibits the reaction [mono-benzyl phthalate results in increased expression of CD36 mRNA]

NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903

G

Cd68 molecule

increases expression

mono-benzyl phthalate results in increased expression of CD68 mRNA

NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,381,815...54,383,697

G

cyclin dependent kinase 2

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDK2 mRNA

NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,129,811...1,137,403

G

cyclin-dependent kinase 4

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDK4 mRNA

NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase inhibitor 1A

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CDKN1A mRNA

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1B

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDKN1B mRNA

NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982

G

cyclin-dependent kinase inhibitor 1C

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDKN1C mRNA

NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:198,655,407...198,658,048

G

cyclin-dependent kinase inhibitor 2A

multiple interactions
increases methylation
decreases expression

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CDKN2A mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDKN2A mRNA
mono-benzyl phthalate results in increased methylation of CDKN2A promoter
mono-benzyl phthalate results in decreased expression of CDKN2A mRNA

PMID:31884101 PMID:35487445 PMID:35861251

NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149

G

cyclin-dependent kinase inhibitor 2B

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CDKN2B mRNA; [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate] results in increased expression of CDKN2B mRNA

PMID:31884101 PMID:33511402

NCBI chr 5:109,123,308...109,134,906
Ensembl chr 5:104,010,680...104,019,050

G

cyclin-dependent kinase inhibitor 2C

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDKN2C mRNA

NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:124,411,124...124,416,278

G

cyclin dependent kinase inhibitor 2D

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of CDKN2D mRNA

NCBI chr 8:28,108,036...28,110,809
Ensembl chr 8:19,831,866...19,834,674

G

glycoprotein hormones, alpha polypeptide

increases expression
affects expression
increases secretion

mono-benzyl phthalate results in increased expression of CGA mRNA
mono-benzyl phthalate affects the expression of CGA mRNA
mono-benzyl phthalate results in increased secretion of CGA protein

PMID:28381288 PMID:29089286

NCBI chr 5:54,283,109...54,295,464
Ensembl chr 5:49,487,068...49,499,191

G

C-reactive protein

increases expression

mono-benzyl phthalate results in increased expression of CRP protein

NCBI chr13:87,694,062...87,695,978
Ensembl chr13:85,124,977...85,175,178

G

C-X-C motif chemokine ligand 10

multiple interactions

[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased expression of CXCL10 mRNA

NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,704,758...15,706,975

G

cytochrome P450, family 11, subfamily a, polypeptide 1

increases expression
multiple interactions
affects expression

mono-benzyl phthalate results in increased expression of CYP11A1 mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CYP11A1 mRNA
mono-benzyl phthalate affects the expression of CYP11A1 mRNA

PMID:28381288 PMID:29089286 PMID:31884101

NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:58,404,669...58,434,338

G

cytochrome P450, family 17, subfamily a, polypeptide 1

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CYP17A1 mRNA

NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:245,535,462...245,541,573

G

cytochrome P450, family 19, subfamily a, polypeptide 1

affects expression
multiple interactions

mono-benzyl phthalate affects the expression of CYP19A1 mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CYP19A1 mRNA

PMID:28381288 PMID:31884101

NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:54,553,165...54,580,758

G

cytochrome P450, family 1, subfamily a, polypeptide 1

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CYP1A1 mRNA

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily b, polypeptide 1

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CYP1B1 mRNA

NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 2, subfamily b, polypeptide 1

decreases activity

mono-benzyl phthalate results in decreased activity of CYP2B1 protein

NCBI chr 1:90,646,098...90,669,762
Ensembl chr 1:81,518,408...81,542,052

G

cytochrome P450, family 3, subfamily a, polypeptide 62

decreases activity

mono-benzyl phthalate results in decreased activity of CYP3A62 protein

NCBI chr12:21,511,763...21,547,598
Ensembl chr12:16,397,998...16,433,833

G

dephospho-CoA kinase domain containing

multiple interactions

[mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono(2-ethyl-5-oxohexyl)phthalate co-treated with 2-ethyl-5-carboxypentyl phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with monoethyl phthalate co-treated with monobutyl phthalate] affects the expression of DCAKD mRNA

NCBI chr10:87,957,738...87,989,002
Ensembl chr10:87,957,740...87,980,054

G

dicer 1 ribonuclease III

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of DICER1 mRNA

NCBI chr 6:129,392,298...129,457,252
Ensembl chr 6:123,631,250...123,693,965

G

DNA methyltransferase 1

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of DNMT1 mRNA; [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of DNMT1 mRNA

NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:19,440,611...19,486,659

G

drosha ribonuclease III

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of DROSHA mRNA

NCBI chr 2:63,591,885...63,703,688
Ensembl chr 2:61,864,970...61,976,688

G

epiregulin

increases expression

mono-benzyl phthalate results in increased expression of EREG mRNA

NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,027,287...17,041,062

G

estrogen receptor 1

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of ESR1 mRNA; mono-benzyl phthalate promotes the reaction [Estradiol results in increased activity of ESR1 protein]
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of ESR1 mRNA

PMID:28571686 PMID:31884101 PMID:35861251

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

multiple interactions

mono-benzyl phthalate promotes the reaction [Estradiol results in increased activity of ESR2 protein]
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of ESR2 mRNA

PMID:28571686 PMID:31884101

NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919

G

exosome component 1

multiple interactions

[mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono(2-ethyl-5-oxohexyl)phthalate co-treated with 2-ethyl-5-carboxypentyl phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate metabolite co-treated with monoethyl phthalate co-treated with monobutyl phthalate] affects the expression of EXOSC1 mRNA; [mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with methylparaben] results in decreased expression of EXOSC1 mRNA

NCBI chr 1:240,734,777...240,745,431
Ensembl chr 1:240,734,773...240,745,438

G

fatty acid binding protein 4

multiple interactions
increases expression

T 0070907 inhibits the reaction [mono-benzyl phthalate results in increased expression of FABP4 mRNA]

NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:91,580,885...91,585,578

G

filaggrin

multiple interactions

[FLG gene polymorphism affects the susceptibility to butylbenzyl phthalate] which affects the abundance of mono-benzyl phthalate

NCBI chr 2:178,884,793...178,912,986

G

follicle stimulating hormone receptor

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of FSHR mRNA

NCBI chr 6:10,952,329...11,160,288
Ensembl chr 6:5,198,825...5,406,785

G

glucosamine-6-phosphate deaminase 1

multiple interactions

[mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with methylparaben] affects the expression of GNPDA1 mRNA

NCBI chr18:30,416,599...30,428,630
Ensembl chr18:30,165,427...30,177,486

G

golgi reassembly stacking protein 2

multiple interactions

[mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono(2-ethyl-5-oxohexyl)phthalate co-treated with 2-ethyl-5-carboxypentyl phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate metabolite co-treated with monoethyl phthalate co-treated with monobutyl phthalate] results in decreased expression of GORASP2 mRNA; [mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with methylparaben] affects the expression of GORASP2 mRNA

NCBI chr 3:55,474,448...55,503,570
Ensembl chr 3:55,474,757...55,503,576

G

glutathione peroxidase 1

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of GPX1 mRNA

NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024

G

glutathione-disulfide reductase

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of GSR mRNA

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661

G

haptoglobin

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate] results in increased expression of HP mRNA

NCBI chr19:54,449,151...54,453,701
Ensembl chr19:37,539,627...37,544,523

G

hydroxysteroid (17-beta) dehydrogenase 1

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of HSD17B1 mRNA

NCBI chr10:86,510,011...86,512,211
Ensembl chr10:86,009,728...86,011,927

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of HSD3B1 mRNA; [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate] results in decreased expression of HSD3B1 mRNA

PMID:31884101 PMID:39150890

NCBI chr 2:188,858,574...188,864,694
Ensembl chr 2:186,169,863...186,175,999

G

interleukin 6

multiple interactions

[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased expression of IL6 mRNA

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178

G

luteinizing hormone/choriogonadotropin receptor

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of LHCGR mRNA

NCBI chr 6:11,415,361...11,480,834
Ensembl chr 6:5,661,871...5,724,521

G

monoglyceride lipase

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate] results in increased expression of MGLL mRNA

NCBI chr 4:122,749,436...122,851,440
Ensembl chr 4:121,192,195...121,294,179

G

microRNA 126a

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR126

NCBI chr 3:29,813,150...29,813,267
Ensembl chr 3:9,415,063...9,415,180

G

microRNA 127

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR127

NCBI chr 6:134,328,454...134,328,550
Ensembl chr 6:128,546,215...128,546,311

G

microRNA 141

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of MIR141 mRNA

NCBI chr 4:159,209,525...159,209,618
Ensembl chr 4:157,523,239...157,523,332

G

microRNA 143

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR143

NCBI chr18:57,371,349...57,371,453
Ensembl chr18:55,101,006...55,101,110

G

microRNA 150

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR150

NCBI chr 1:104,741,487...104,741,571
Ensembl chr 1:95,605,024...95,605,108

G

microRNA 184

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of MIR184 mRNA

NCBI chr 8:90,343,134...90,343,210
Ensembl chr 8:90,343,134...90,343,210

G

microRNA 193a

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR193A

NCBI chr10:65,170,306...65,170,417
Ensembl chr10:64,672,343...64,672,454

G

microRNA 221

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR221

NCBI chr X:6,023,182...6,023,290
Ensembl chr X:3,429,465...3,429,573

G

microRNA 25

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR25

NCBI chr12:22,156,641...22,156,724
Ensembl chr12:17,042,932...17,043,015

G

microRNA 320a

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR320A

NCBI chr15:51,926,088...51,926,169
Ensembl chr15:45,516,392...45,516,473

G

microRNA 324

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR324

NCBI chr10:55,233,363...55,233,445
Ensembl chr10:54,734,678...54,734,766

G

microRNA 328

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR328

NCBI chr19:33,184,766...33,184,849
Ensembl chr19:33,184,766...33,184,849

G

microRNA 345

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR345

NCBI chr 6:127,754,027...127,754,122
Ensembl chr 6:127,754,027...127,754,122

G

microRNA 451a

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR451A

NCBI chr10:63,459,569...63,459,640
Ensembl chr10:62,961,520...62,961,591

G

microRNA 532

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR532

NCBI chr X:17,919,185...17,919,263
Ensembl chr X:15,247,315...15,247,393

G

microRNA 99b

multiple interactions

[butylbenzyl phthalate results in increased abundance of mono-benzyl phthalate] which affects the secretion of MIR99B

NCBI chr 1:67,350,064...67,350,133
Ensembl chr 1:58,677,011...58,677,090

G

marker of proliferation Ki-67

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of MKI67 mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of MKI67 mRNA

PMID:31884101 PMID:35861251

NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:190,496,319...190,522,762

G

matrix metallopeptidase 9

multiple interactions

[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased secretion of MMP9 protein

NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120

G

mannose receptor, C type 1

multiple interactions

[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in decreased expression of MRC1 mRNA

NCBI chr17:82,157,725...82,239,411
Ensembl chr17:77,249,187...77,330,857

G

nuclear receptor subfamily 1, group I, member 2

increases activity

mono-benzyl phthalate results in increased activity of NR1I2 protein

NCBI chr11:75,965,717...76,006,733
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor subfamily 1, group I, member 3

increases activity
multiple interactions

mono-benzyl phthalate results in increased activity of NR1I3 protein alternative form
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of NR1I3 mRNA

PMID:27551952 PMID:31884101

NCBI chr13:86,165,327...86,170,362
Ensembl chr13:83,632,899...83,637,906

G

phosphoribosylformylglycinamidine synthase

multiple interactions

[mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono(2-ethyl-5-oxohexyl)phthalate co-treated with 2-ethyl-5-carboxypentyl phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with monoethyl phthalate co-treated with monobutyl phthalate] affects the expression of PFAS mRNA

NCBI chr10:54,189,157...54,210,685
Ensembl chr10:53,691,626...53,708,420

G

perilipin 1

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate] results in increased expression of PLIN1 mRNA

NCBI chr 1:143,073,612...143,086,199
Ensembl chr 1:133,664,892...133,676,828

G

phospholipid transfer protein

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate] results in increased expression of PLTP mRNA

NCBI chr 3:173,994,162...174,011,982
Ensembl chr 3:153,574,825...153,592,647

G

peroxisome proliferator activated receptor alpha

affects binding
multiple interactions
increases activity

mono-benzyl phthalate binds to PPARA protein
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of PPARA mRNA
mono-benzyl phthalate results in increased activity of PPARA protein

PMID:23843199 PMID:27551952 PMID:31884101

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346

G

peroxisome proliferator-activated receptor delta

affects binding
multiple interactions
increases activity

mono-benzyl phthalate binds to PPARB protein
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of PPARD mRNA
mono-benzyl phthalate results in increased activity of PPARD protein

PMID:23843199 PMID:27551952 PMID:31884101

NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,298,785...6,363,968

G

peroxisome proliferator-activated receptor gamma

affects binding
multiple interactions
increases expression
increases activity

mono-benzyl phthalate binds to PPARG protein
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of PPARG mRNA
mono-benzyl phthalate results in increased expression of PPARG protein
mono-benzyl phthalate results in increased activity of PPARG protein

PMID:23843199 PMID:27551952 PMID:29089286 PMID:31884101

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468

G

prostaglandin-endoperoxide synthase 2

affects expression

mono-benzyl phthalate affects the expression of PTGS2 mRNA

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188

G

sex hormone binding globulin

multiple interactions
decreases secretion

[Phthalic Acids results in increased abundance of mono-benzyl phthalate] which results in increased expression of and results in increased secretion of SHBG protein
mono-benzyl phthalate results in decreased secretion of SHBG protein

PMID:24945889 PMID:28637469

NCBI chr10:54,831,716...54,849,162
Ensembl chr10:54,332,941...54,351,057

G

S-phase kinase associated protein 2

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of SKP2 mRNA

NCBI chr 2:59,888,406...59,916,471
Ensembl chr 2:58,161,229...58,189,338

G

superoxide dismutase 1

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of SOD1 mRNA

NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249

G

steroidogenic acute regulatory protein

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of STAR mRNA; [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate] results in increased expression of STAR mRNA

PMID:31884101 PMID:39150890

NCBI chr16:72,969,824...72,974,447
Ensembl chr16:66,264,807...66,271,672

G

tumor necrosis factor

increases expression

mono-benzyl phthalate results in increased expression of TNF mRNA

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629

G

tumor protein p53

decreases expression
increases methylation

mono-benzyl phthalate results in decreased expression of TP53 mRNA
mono-benzyl phthalate results in increased methylation of TP53 promoter

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524

G

tumor protein p53 inducible protein 13

multiple interactions

[mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono(2-ethyl-5-oxohexyl)phthalate co-treated with 2-ethyl-5-carboxypentyl phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate metabolite co-treated with monoethyl phthalate co-treated with monobutyl phthalate] results in decreased expression of TP53I13 mRNA; [mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with methylparaben] results in increased expression of TP53I13 mRNA

NCBI chr10:62,356,722...62,363,122
Ensembl chr10:62,356,722...62,361,343

monohexyl phthalate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

heat shock transcription factor 1

increases activity

mono-n-hexyl phthalate results in increased activity of HSF1 protein

NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:108,196,056...108,223,011

G

peroxisome proliferator activated receptor alpha

affects binding

mono-n-hexyl phthalate binds to PPARA protein

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346

G

peroxisome proliferator-activated receptor delta

affects binding

mono-n-hexyl phthalate binds to PPARB protein

NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,298,785...6,363,968

G

peroxisome proliferator-activated receptor gamma

affects binding

mono-n-hexyl phthalate binds to PPARG protein

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468

musk xylene

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression
increases activity

musk xylene results in increased expression of CYP1A1 protein
musk xylene results in increased activity of CYP1A1 protein

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily a, polypeptide 2

increases expression
increases activity

musk xylene results in increased expression of CYP1A2 protein
musk xylene metabolite results in increased expression of CYP1A2 mRNA; musk xylene results in increased expression of CYP1A2 mRNA
musk xylene results in increased activity of CYP1A2 protein

PMID:9397191 PMID:10630706

NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 2, subfamily b, polypeptide 1

affects activity
increases expression

musk xylene affects the activity of CYP2B1 protein
musk xylene results in increased expression of CYP2B1 mRNA; musk xylene results in increased expression of CYP2B1 protein

NCBI chr 1:90,646,098...90,669,762
Ensembl chr 1:81,518,408...81,542,052

G

cytochrome P450, family 2, subfamily b, polypeptide 2

affects activity
increases expression

musk xylene affects the activity of CYP2B2 protein
musk xylene results in increased expression of CYP2B2 protein

NCBI chr 1:90,722,243...90,736,272
Ensembl chr 1:81,594,555...81,608,566

G

cytochrome P450, family 3, subfamily a, polypeptide 2

increases activity
increases expression

musk xylene results in increased activity of CYP3A2 protein
musk xylene results in increased expression of CYP3A2 protein

NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1

increases activity
increases expression

musk xylene results in increased activity of CYP3A23-3A1 protein
musk xylene results in increased expression of CYP3A23-3A1 protein

NCBI chr12:14,369,950...14,398,803
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030

raspberry ketone

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetyl-CoA carboxylase alpha

decreases expression

raspberry ketone results in decreased expression of ACACA mRNA

NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,014,170...69,276,457

G

apelin

increases expression
multiple interactions

raspberry ketone results in increased expression of APLN mRNA
raspberry ketone inhibits the reaction [Dietary Fats results in increased expression of APLN mRNA]

NCBI chr X:132,058,739...132,091,518
Ensembl chr X:127,203,823...127,213,391

G

androgen receptor

multiple interactions

raspberry ketone binds to and results in decreased activity of AR protein

NCBI chr X:67,135,317...67,304,476
Ensembl chr X:63,104,771...63,273,925

G

carnitine palmitoyltransferase 1c

increases expression

raspberry ketone results in increased expression of CPT1C mRNA

NCBI chr 1:104,579,297...104,593,824
Ensembl chr 1:95,442,817...95,457,342

G

DNA-damage inducible transcript 3

increases expression
multiple interactions

raspberry ketone results in increased expression of DDIT3 mRNA
Acetylcysteine inhibits the reaction [raspberry ketone results in increased expression of DDIT3 mRNA]

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201

G

growth arrest and DNA-damage-inducible, alpha

increases expression
multiple interactions

raspberry ketone results in increased expression of GADD45A mRNA
Acetylcysteine inhibits the reaction [raspberry ketone results in increased expression of GADD45A mRNA]

NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:96,154,789...96,157,115

G

glutamic--pyruvic transaminase

multiple interactions

[raspberry ketone co-treated with Resveratrol] inhibits the reaction [Carbon Tetrachloride results in increased expression of GPT protein]; raspberry ketone inhibits the reaction [Carbon Tetrachloride results in increased expression of GPT protein]

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494

G

glutathione peroxidase 1

multiple interactions
decreases expression

Acetylcysteine inhibits the reaction [raspberry ketone results in decreased expression of GPX1 protein]

NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024

G

heme oxygenase 1

affects expression

raspberry ketone affects the expression of HMOX1 mRNA

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079

G

interleukin 10

multiple interactions

[Resveratrol co-treated with raspberry ketone] inhibits the reaction [Carbon Tetrachloride results in decreased expression of IL10 mRNA]; raspberry ketone inhibits the reaction [Carbon Tetrachloride results in decreased expression of IL10 mRNA]

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313

G

interleukin 1 beta

multiple interactions

[Resveratrol co-treated with raspberry ketone] inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B mRNA]; raspberry ketone inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B mRNA]

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

increases expression
multiple interactions

raspberry ketone results in increased expression of IL6 mRNA
[Resveratrol co-treated with raspberry ketone] inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 mRNA]; raspberry ketone inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 mRNA]

PMID:36460224 PMID:37009719

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178

G

potassium voltage-gated channel subfamily C member 3

multiple interactions
increases expression

raspberry ketone inhibits the reaction [Dietary Fats results in increased expression of KCNC3 mRNA]
raspberry ketone results in increased expression of KCNC3 mRNA

NCBI chr 1:95,080,960...95,095,165
Ensembl chr 1:95,080,960...95,095,160

G

matrix metallopeptidase 9

multiple interactions

[raspberry ketone co-treated with Resveratrol] inhibits the reaction [Carbon Tetrachloride results in decreased expression of MMP9 protein]; [Resveratrol co-treated with raspberry ketone] inhibits the reaction [Carbon Tetrachloride results in decreased expression of MMP9 mRNA]; raspberry ketone inhibits the reaction [Carbon Tetrachloride results in decreased expression of MMP9 mRNA]; raspberry ketone inhibits the reaction [Carbon Tetrachloride results in decreased expression of MMP9 protein]

NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120

G

NFE2 like bZIP transcription factor 2

affects expression

raspberry ketone affects the expression of NFE2L2 mRNA

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737

G

NAD(P)H quinone dehydrogenase 1

affects expression

raspberry ketone affects the expression of NQO1 mRNA

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557

G

olfactory receptor family 5 subfamily D member 18

multiple interactions

raspberry ketone binds to and results in increased activity of OR5D18 protein

NCBI chr 3:93,972,754...93,973,695
Ensembl chr 3:73,516,364...73,519,858
Ensembl chr 3:73,516,364...73,519,858

G

patatin-like phospholipase domain containing 2

increases expression

raspberry ketone results in increased expression of PNPLA2 mRNA

NCBI chr 1:205,982,279...205,987,361
Ensembl chr 1:196,552,723...196,557,805

G

peroxisome proliferator activated receptor alpha

increases expression

raspberry ketone results in increased expression of PPARA mRNA

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346

G

peroxisome proliferator-activated receptor gamma

increases expression

raspberry ketone results in increased expression of PPARG mRNA

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468

G

transforming growth factor, beta 1

multiple interactions

[Resveratrol co-treated with raspberry ketone] inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]; raspberry ketone inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847

G

TIMP metallopeptidase inhibitor 1

multiple interactions

[raspberry ketone co-treated with Resveratrol] inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]; raspberry ketone inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]

NCBI chr X:3,766,509...3,772,578
Ensembl chr X:1,212,972...1,217,664

G

tumor necrosis factor

increases expression
multiple interactions

raspberry ketone results in increased expression of TNF mRNA
[Resveratrol co-treated with raspberry ketone] inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]; raspberry ketone inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]

PMID:36460224 PMID:37009719

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629

salicin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

albumin

multiple interactions

ALB protein binds to and affects the transport of salicin

NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,607,381...17,622,836

G

taste receptor, type 2, member 118

multiple interactions
increases activity

4-((diethylamino)sulfonyl)benzoic acid inhibits the reaction [salicin results in increased activity of TAS2R16 protein]; Probenecid inhibits the reaction [salicin results in increased activity of TAS2R16 protein]

NCBI chr 4:53,414,815...53,415,714
Ensembl chr 4:52,449,208...52,450,107

salicyl alcohol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

albumin

multiple interactions

ALB protein binds to and affects the transport of salicyl alcohol

NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,607,381...17,622,836

G

butyrylcholinesterase

multiple interactions

[2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide binds to and results in decreased activity of BCHE protein] which results in increased abundance of salicyl alcohol

NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:158,307,584...158,401,148

G

superoxide dismutase 2

multiple interactions

salicyl alcohol inhibits the reaction [2,2'-azobis(2-amidinopropane) results in decreased activity of SOD2 protein]

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189

sclareol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acid phosphatase 5, tartrate resistant

multiple interactions
decreases expression

sclareol inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]; sclareol inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 protein]
sclareol results in decreased expression of ACP5 mRNA; sclareol results in decreased expression of ACP5 protein

NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:20,663,985...20,667,929

G

AKT serine/threonine kinase 1

multiple interactions
decreases phosphorylation

sclareol results in decreased expression of and results in decreased phosphorylation of AKT1 protein
sclareol results in decreased phosphorylation of AKT1 protein

PMID:33164868 PMID:33423118

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921

G

ATPase H+ transporting V0 subunit D2

decreases expression
multiple interactions

sclareol results in decreased expression of ATP6V0D2 mRNA
sclareol inhibits the reaction [TNFSF11 protein results in increased expression of ATP6V0D2 mRNA]

NCBI chr 5:38,133,151...38,182,245
Ensembl chr 5:33,336,264...33,385,354

G

BCL2, apoptosis regulator

decreases expression

sclareol results in decreased expression of BCL2 protein

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 1

decreases expression

sclareol results in decreased expression of BCL2L1 protein

NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479

G

bone gamma-carboxyglutamate protein

increases expression

sclareol results in increased expression of BGLAP mRNA

NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:173,838,518...173,839,495

G

baculoviral IAP repeat-containing 5

decreases expression

sclareol results in decreased expression of BIRC5 protein

NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380

G

caspase 3

increases cleavage
multiple interactions

sclareol results in increased cleavage of CASP3 protein
[ferrostatin-1 co-treated with sclareol] results in increased cleavage of CASP3 protein

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648

G

caspase 9

increases cleavage

sclareol results in increased cleavage of CASP9 protein

Ensembl chr 5:154,109,046...154,126,626

G

cellular communication network factor 1

increases expression
multiple interactions

sclareol results in increased expression of CCN1 mRNA; sclareol results in increased expression of CCN1 protein
[sclareol co-treated with SB 203580] results in increased expression of CCN1 protein; sclareol inhibits the reaction [TNFSF11 protein results in decreased expression of CCN1 protein]

NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:234,562,408...234,565,484

G

cyclin D1

decreases expression

sclareol results in decreased expression of CCND1 protein

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602

G

cyclin-dependent kinase inhibitor 1A

increases expression

sclareol results in increased expression of CDKN1A protein

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 2A

increases expression

sclareol results in increased expression of CDKN2A protein

NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149

G

cathepsin K

decreases expression
multiple interactions

sclareol results in decreased expression of CTSK mRNA; sclareol results in decreased expression of CTSK protein
sclareol inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; sclareol inhibits the reaction [TNFSF11 protein results in increased expression of CTSK protein]

NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:183,058,569...183,069,550

G

dendrocyte expressed seven transmembrane protein

decreases expression
multiple interactions

sclareol results in decreased expression of DCSTAMP mRNA
sclareol inhibits the reaction [TNFSF11 protein results in increased expression of DCSTAMP mRNA]

NCBI chr 7:72,692,364...72,706,983
Ensembl chr 7:70,807,581...70,822,078

G

ERCC excision repair 1, endonuclease non-catalytic subunit

multiple interactions
decreases expression

[sclareol co-treated with Cisplatin] results in decreased expression of ERCC1 protein
sclareol results in decreased expression of ERCC1 protein

NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:78,996,390...79,007,963

G

Fos proto-oncogene, AP-1 transcription factor subunit

decreases expression
multiple interactions

sclareol results in decreased expression of FOS protein
sclareol inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; sclareol inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein]
sclareol results in decreased expression of FOS mRNA; sclareol results in decreased expression of FOS protein

PMID:33164868 PMID:33423118

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036

G

ferritin heavy chain 1

decreases expression

sclareol results in decreased expression of FTH1 protein

NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:206,627,103...206,725,424

G

glutathione peroxidase 4

multiple interactions
decreases expression

[ferrostatin-1 co-treated with sclareol] results in decreased expression of GPX4 protein
sclareol results in decreased expression of GPX4 protein

NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:9,650,185...9,652,982

G

glycogen synthase kinase 3 beta

decreases phosphorylation

sclareol results in decreased phosphorylation of GSK3B protein

NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646

G

Jun proto-oncogene, AP-1 transcription factor subunit

decreases expression

sclareol results in decreased expression of JUN protein

NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656

G

mitogen activated protein kinase 1

multiple interactions
decreases phosphorylation

[sclareol co-treated with TNFSF11 protein] results in decreased phosphorylation of MAPK1 protein
sclareol results in decreased phosphorylation of MAPK1 protein

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

decreases phosphorylation
multiple interactions

sclareol results in decreased phosphorylation of MAPK3 protein
[sclareol co-treated with TNFSF11 protein] results in decreased phosphorylation of MAPK3 protein

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863

G

nuclear factor of activated T-cells 1

decreases expression
multiple interactions

sclareol results in decreased expression of NFATC1 mRNA; sclareol results in decreased expression of NFATC1 protein
sclareol inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; sclareol inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]

NCBI chr18:76,321,386...76,430,997
Ensembl chr18:74,046,904...74,156,028

G

poly (ADP-ribose) polymerase 1

increases cleavage

sclareol results in increased cleavage of PARP1 protein

NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404

G

RUNX family transcription factor 2

increases expression

sclareol results in increased expression of RUNX2 mRNA; sclareol results in increased expression of RUNX2 protein

NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:16,167,482...16,492,167

G

solute carrier family 40 member 1

decreases expression

sclareol results in decreased expression of SLC40A1 protein

NCBI chr 9:55,525,457...55,633,463
Ensembl chr 9:48,033,526...48,051,481

G

snail family transcriptional repressor 1

decreases expression

sclareol results in decreased expression of SNAI1 protein

NCBI chr 3:176,667,476...176,671,965
Ensembl chr 3:156,248,485...156,252,969

G

secreted phosphoprotein 1

increases expression

sclareol results in increased expression of SPP1 mRNA; sclareol results in increased expression of SPP1 protein

NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,308,885...5,315,162

G

transferrin receptor

decreases expression

sclareol results in decreased expression of TFRC protein

NCBI chr11:81,668,478...81,690,318
Ensembl chr11:68,163,413...68,185,257

G

TNF superfamily member 11

multiple interactions

[sclareol co-treated with TNFSF11 protein] results in decreased phosphorylation of MAPK1 protein; [sclareol co-treated with TNFSF11 protein] results in decreased phosphorylation of MAPK3 protein; sclareol inhibits the reaction [TNFSF11 protein results in decreased expression of CCN1 protein]; sclareol inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]; sclareol inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 protein]; sclareol inhibits the reaction [TNFSF11 protein results in increased expression of ATP6V0D2 mRNA]; sclareol inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; sclareol inhibits the reaction [TNFSF11 protein results in increased expression of CTSK protein]; sclareol inhibits the reaction [TNFSF11 protein results in increased expression of DCSTAMP mRNA]; sclareol inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; sclareol inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein]; sclareol inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; sclareol inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]

NCBI chr15:60,083,008...60,114,479
Ensembl chr15:53,673,877...53,705,445

zingerone

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetyl-CoA carboxylase alpha

multiple interactions

zingerone inhibits the reaction [[Cholesterol, Dietary co-treated with Cholic Acid] results in increased expression of ACACA mRNA]

NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,014,170...69,276,457

G

acetylcholinesterase

multiple interactions
affects activity

zingerone affects the reaction [Vancomycin affects the activity of ACHE protein]
zingerone affects the activity of ACHE protein

NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651

G

acyl-CoA oxidase 1

multiple interactions

zingerone inhibits the reaction [[Cholesterol, Dietary co-treated with Cholic Acid] results in decreased expression of ACOX1 mRNA]

NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,406,197...101,431,232

G

acyl-CoA synthetase long-chain family member 1

multiple interactions

zingerone inhibits the reaction [[Cholesterol, Dietary co-treated with Cholic Acid] results in increased expression of ACSL1 mRNA]

NCBI chr16:52,487,870...52,554,110
Ensembl chr16:45,755,254...45,821,541

G

AKT serine/threonine kinase 1

multiple interactions

zingerone results in decreased expression of and results in decreased phosphorylation of AKT1 protein

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921

G

AKT serine/threonine kinase 2

multiple interactions
increases expression

zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of AKT2 mRNA]
zingerone results in increased expression of AKT2 mRNA

NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:82,883,547...82,933,817

G

androgen receptor

multiple interactions

zingerone binds to and results in decreased activity of AR protein

NCBI chr X:67,135,317...67,304,476
Ensembl chr X:63,104,771...63,273,925

G

BCL2 associated X, apoptosis regulator

multiple interactions
increases expression

zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BAX mRNA]; zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BAX protein]; zingerone inhibits the reaction [Ethanol results in increased expression of BAX protein]
zingerone results in increased expression of BAX protein

PMID:28442378 PMID:31476248 PMID:36822304

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368

G

butyrylcholinesterase

affects activity
multiple interactions

zingerone affects the activity of BCHE protein
zingerone affects the reaction [Vancomycin affects the activity of BCHE protein]

NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:158,307,584...158,401,148

G

BCL2, apoptosis regulator

multiple interactions
increases expression
decreases expression

zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of BCL2 mRNA]; zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of BCL2 protein]; zingerone inhibits the reaction [Ethanol results in decreased expression of BCL2 protein]
zingerone results in increased expression of BCL2 mRNA
zingerone results in decreased expression of BCL2 protein

PMID:28442378 PMID:31476248 PMID:36822304

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

beclin 1

multiple interactions

zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BECN1 mRNA]

NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742

G

BH3 interacting domain death agonist

increases expression

zingerone results in increased expression of BID protein

NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:154,113,198...154,134,720

G

caspase 3

multiple interactions

zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CASP3 mRNA]; zingerone inhibits the reaction [Ethanol results in increased expression of CASP3 protein]

PMID:28442378 PMID:36822304

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648

G

caspase 9

multiple interactions

zingerone inhibits the reaction [Ethanol results in increased expression of CASP9 protein]

Ensembl chr 5:154,109,046...154,126,626

G

catalase

multiple interactions

zingerone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CAT protein]; zingerone inhibits the reaction [[Cholesterol, Dietary co-treated with Cholic Acid] results in decreased activity of CAT protein]; zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased activity of CAT protein]

PMID:31476248 PMID:33845646 PMID:36822304

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478

G

cyclin D1

multiple interactions

zingerone inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CCND1]

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602

G

carnitine palmitoyltransferase 1A

multiple interactions

zingerone inhibits the reaction [[Cholesterol, Dietary co-treated with Cholic Acid] results in decreased expression of CPT1A mRNA]

NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055

G

cytochrome b5 type A

multiple interactions

zingerone inhibits the reaction [Ethanol results in increased activity of CYB5A protein]

NCBI chr18:80,487,923...80,520,544
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535

G

cytochrome b5 reductase 3

multiple interactions

zingerone inhibits the reaction [Ethanol results in increased activity of CYB5R3 protein]

NCBI chr 7:116,186,729...116,204,290
Ensembl chr 7:114,306,685...114,324,298

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions

zingerone inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CYP2E1 protein]; zingerone inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]

PMID:28442378 PMID:30720227

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023

G

fatty acid synthase

multiple interactions

zingerone inhibits the reaction [[Cholesterol, Dietary co-treated with Cholic Acid] results in increased expression of FASN mRNA]

NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261

G

forkhead box O1

multiple interactions
increases expression

zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of FOXO1 mRNA]
zingerone results in increased expression of FOXO1 mRNA

NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:136,312,168...136,387,790

G

glutathione-disulfide reductase

multiple interactions

zingerone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of GSR protein]

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661

G

3-hydroxy-3-methylglutaryl-CoA reductase

multiple interactions

zingerone inhibits the reaction [Ethanol results in increased activity of HMGCR protein]

NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703

G

interferon gamma

multiple interactions

zingerone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IFNG protein]

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375

G

interleukin 1 beta

multiple interactions
decreases expression

zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of IL1B mRNA]
zingerone results in decreased expression of IL1B mRNA; zingerone results in decreased expression of IL1B protein

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

multiple interactions

zingerone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein]
zingerone inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of IL6 protein]; zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of IL6 mRNA]

PMID:29289488 PMID:30720227 PMID:36822304

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178

G

interferon regulatory factor 3

multiple interactions

zingerone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of IRF3 protein]

NCBI chr 1:104,616,608...104,621,402
Ensembl chr 1:95,479,821...95,484,935

G

lecithin cholesterol acyltransferase

multiple interactions

zingerone inhibits the reaction [Ethanol results in decreased activity of LCAT protein]

NCBI chr19:50,744,598...50,748,064
Ensembl chr19:33,834,403...33,838,231

G

lipoprotein lipase

multiple interactions

zingerone inhibits the reaction [Ethanol results in decreased activity of LPL protein]

NCBI chr16:25,596,205...25,621,928
Ensembl chr16:20,829,465...20,855,249

G

mitogen activated protein kinase 1

decreases phosphorylation

zingerone results in decreased phosphorylation of MAPK1 protein

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 14

multiple interactions

zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of MAPK14 mRNA]

NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,749,670...6,810,589

G

mitogen-activated protein kinase 15

multiple interactions

zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of MAPK15 mRNA]

NCBI chr 7:109,575,619...109,595,339
Ensembl chr 7:107,694,964...107,714,645

G

mitogen activated protein kinase 3

decreases phosphorylation

zingerone results in decreased phosphorylation of MAPK3 protein

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863

G

mitogen-activated protein kinase 8

multiple interactions
increases expression

zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of MAPK8 mRNA]
zingerone results in increased expression of MAPK8 mRNA

NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981

G

marker of proliferation Ki-67

multiple interactions

zingerone inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of MKI67 protein]

NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:190,496,319...190,522,762

G

mechanistic target of rapamycin kinase

multiple interactions

zingerone results in decreased expression of and results in decreased phosphorylation of MTOR protein

NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311

G

NFE2 like bZIP transcription factor 2

multiple interactions

zingerone inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of NFE2L2 protein]

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737

G

nuclear factor kappa B subunit 1

affects localization
multiple interactions
decreases expression

zingerone affects the localization of NFKB1 protein
zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of NFKB1 mRNA]
zingerone results in decreased expression of NFKB1 mRNA

PMID:20211236 PMID:36822304

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404

G

NFKB inhibitor alpha

multiple interactions

zingerone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of NFKBIA protein]

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941

G

nitric oxide synthase 2

decreases expression
multiple interactions

zingerone results in decreased expression of NOS2 protein
zingerone inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of NOS2 protein]; zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of NOS2 mRNA]

PMID:20211236 PMID:30720227 PMID:36822304

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210

G

NPHS1 adhesion molecule, nephrin

multiple interactions

zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NPHS1 protein]

NCBI chr 1:94,848,261...94,876,522
Ensembl chr 1:85,720,812...85,749,078

G

NAD(P)H quinone dehydrogenase 1

multiple interactions

zingerone inhibits the reaction [Ethanol results in decreased activity of NQO1 protein]

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557

G

nuclear receptor subfamily 1, group H, member 3

multiple interactions

zingerone inhibits the reaction [[Cholesterol, Dietary co-treated with Cholic Acid] results in increased expression of NR1H3 mRNA]

NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:77,158,808...77,168,722

G

olfactory receptor family 5 subfamily D member 18

multiple interactions

zingerone binds to and results in increased activity of OR5D18 protein

NCBI chr 3:93,972,754...93,973,695
Ensembl chr 3:73,516,364...73,519,858
Ensembl chr 3:73,516,364...73,519,858

G

proliferating cell nuclear antigen

multiple interactions

zingerone inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PCNA protein]

NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:119,498,810...119,502,995

G

paraoxonase 1

multiple interactions
affects activity

zingerone affects the reaction [Vancomycin results in decreased activity of PON1 protein]
zingerone affects the activity of PON1 protein

NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:33,294,722...33,321,360

G

cytochrome p450 oxidoreductase

multiple interactions

zingerone inhibits the reaction [Ethanol results in increased activity of POR protein]

NCBI chr12:26,587,674...26,655,612
Ensembl chr12:20,951,058...20,999,245

G

peroxisome proliferator activated receptor alpha

multiple interactions

zingerone inhibits the reaction [[Cholesterol, Dietary co-treated with Cholic Acid] results in decreased expression of PPARA mRNA]

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346

G

pregnancy-specific beta 1-glycoprotein

multiple interactions

zingerone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CEACAM5 protein]

NCBI chr 1:77,923,170...77,932,605
Ensembl chr 1:77,923,170...77,932,053

G

prostaglandin-endoperoxide synthase 2

decreases expression
multiple interactions

zingerone results in decreased expression of PTGS2 protein
zingerone inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PTGS2 protein]; zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of PTGS2 mRNA]

PMID:20211236 PMID:30720227 PMID:36822304

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

zingerone affects the localization of and results in increased phosphorylation of RELA protein; zingerone inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of RELA protein]

PMID:20211236 PMID:30720227

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484

G

sterol regulatory element binding transcription factor 1

multiple interactions

zingerone inhibits the reaction [[Cholesterol, Dietary co-treated with Cholic Acid] results in increased expression of SREBF1 mRNA]

NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650

G

transforming growth factor, beta 1

multiple interactions

zingerone inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847

G

toll-like receptor 4

multiple interactions

zingerone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein]

NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628

G

tumor necrosis factor

multiple interactions
decreases expression

zingerone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]
zingerone results in decreased expression of TNF mRNA
zingerone inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of TNF protein]; zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TNF mRNA]

PMID:29289488 PMID:30720227 PMID:36822304

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629

G

troponin I3, cardiac type

multiple interactions

zingerone inhibits the reaction [[Cholesterol, Dietary co-treated with Cholic Acid] results in increased expression of TNNI3 protein]

NCBI chr 1:78,342,571...78,346,255
Ensembl chr 1:69,299,900...69,303,580

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19909
role	19880
application	19720
fragrance	1449
(+)-nootkatone	0
(-)-beta-caryophyllene	0
(-)-dihydrocarveol	0
(2,2,3-trimethylcyclopent-3-en-1-yl)acetonitrile	0
(2E,4E)-2,4-hexadien-1-ol +	0
(2E,6Z)-nona-2,6-dien-1-ol	0
(2S,4R)-rose oxide	0
(5Z)-oct-5-enal	0
(E)-oct-2-en-1-ol	0
(S,S)-trans-1-isopropyl-2,3,3,5-tetramethyl-6-succinylindane	0
(Z)-2-penten-1-ol	0
(Z)-hex-3-en-1-ol +	1
1-(2,6,6-trimethylcyclohex-2-en-1-yl)but-2-enone	0
1-[3-(2,2,3-trimethylcyclopent-3-enyl)cyclohex-3-enyl]ethanol	0
1-[4-(2,2,3-trimethylcyclopent-3-enyl)cyclohex-3-enyl]ethanol	0
2-[3-(2,2,3-trimethylcyclopent-3-enyl)cyclohex-3-enyl]propan-2-ol	0
2-ethylfuran	0
2-methyl-4-phenyl-2-butanol	0
2-methylvaleric acid	0
2-phenylethanol +	89
3,5-dimethoxytoluene	0
3-hydroxy-3-methylbut-1-ene	0
3-methylbutyl hexanoate	0
3-phenylpropyl acetate	0
4,5-(methanoxy-2-methylethano)isolongifol-4-ene	0
4,5-(methanoxyethano)isolongifol-4-ene	0
4-hydroxy-2,5-dimethylfuran-3-one +	0
4-isopropylbenzyl alcohol	0
4-methylbenzyl alcohol	0
5-(1-hydroxybutan-2-yl)isolongifol-5-ene	0
5-(1-hydroxypropan-2-yl)isolongifol-5-ene	0
5-(1-hydroxypropan-2-yl)isolongifolane	0
5-(1-methoxybutan-2-yl)isolongifol-5-ene	0
5-(1-oxopropan-2-yl)isolongifol-5-ene	0
5-(2-hydroxyethyl)isolongifol-5-ene	0
5-(2-methoxyethyl)isolongifol-5-ene	0
5-(3-hydroxybutan-2-yl)isolongifol-5-ene	0
6-methoxy-2,6-dimethyloctanal	0
6-methylcoumarin	0
7-methyloctan-1-ol	0
[3-(2,2,3-trimethylcyclopent-3-enyl)cyclohex-3-enyl]methanol	0
[4-(2,2,3-trimethylcyclopent-3-enyl)cyclohex-3-enyl]methanol	0
alpha-campholenaldehyde +	0
alpha-pinene oxide	0
benzaldehyde	7
benzyl alcohol +	908
benzyl cinnamate	10
beta-damascenone	23
beta-ionone +	22
beta-myrcene	2
beta-terpineol	0
bornyl acetate	0
butyl anthranilate	0
butyl benzoate	0
butyl formate	0
camphene +	8
cinnamyl acetate	0
citral +	36
civetone	0
decanal	5
dihydromyrcenol	0
elemol	0
ethyl (2E,4Z)-deca-2,4-dienoate	0
ethyl 2-methylbutyrate	0
ethyl benzoate	0
ethylpyrazine	0
galaxolide	38
geraniol +	399
geranyl acetone	0
geranyl benzoate	0
geranyllinalool +	0
heptan-1-ol	2
hexan-1-ol +	4
hexyl hexanoate	0
hydroxycitronellal	10
jasmolactone +	0
lavandulol +	0
linalool +	149
methyl acetate	0
methyl cinnamate +	0
methyl nonanoate	0
methyl tetradecanoate	0
musk xylene	6
myrcenol	0
nerol +	0
neryl acetate	0
octyl benzoate	0
pentan-2-ol +	0
perillene	0
piperonal	0
propiophenone +	15
propyl acetate	0
pseudoionone	0
raspberry ketone	23
sclareol	31
theaspirane	0
trans-benzylideneacetone	0
traseolide +	0
zingerone	57

paths to the root