Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N,N-diisopropyltryptamine
go back to main search page
Accession:CHEBI:48286 term browser browse the term
Definition:A tryptamine that has formula C16H24N2.
Synonyms:exact_synonym: N-[2-(1H-indol-3-yl)ethyl]-N-(propan-2-yl)propan-2-amine
 related_synonym: DIPT;   Formula=C16H24N2;   InChI=1S/C16H24N2/c1-12(2)18(13(3)4)10-9-14-11-17-16-8-6-5-7-15(14)16/h5-8,11-13,17H,9-10H2,1-4H3;   InChIKey=ZRVAAGAZUWXRIP-UHFFFAOYSA-N;   N,N-bis(1-methylethyl)-1H-indole-3-ethanamine;   N-[2-(1H-indol-3-yl)ethyl]-N-(1-methylethyl)propan-2-amine;   N-[2-(1H-indol-3-yl)ethyl]-N-isopropylpropan-2-amine;   SMILES=CC(C)N(CCc1c[nH]c2ccccc12)C(C)C
 xref: Beilstein:185763;   CAS:14780-24-6
 xref_mesh: MESH:C033695


show annotations for term's descendants           Sort by:
N,N-diisopropyltryptamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
decreases activity		 ISO [N,N-diisopropyltryptamine analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin CTD PMID:26599973 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases activity
multiple interactions		 ISO N,N-diisopropyltryptamine analog results in decreased activity of CYP2B6 protein
[N,N-diisopropyltryptamine analog results in decreased activity of CYP2B6 protein] which results in decreased metabolism of Bupropion		 CTD PMID:26599973 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases activity
multiple interactions		 ISO N,N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein
[N,N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole		 CTD PMID:26599973 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity
multiple interactions		 ISO N,N-diisopropyltryptamine analog results in decreased activity of CYP2D6 protein
[N,N-diisopropyltryptamine analog results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan		 CTD PMID:26599973 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity
multiple interactions		 ISO N,N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein
[N,N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone		 CTD PMID:26599973 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
5-methoxy-N,N-diisopropyltryptamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases activity
multiple interactions		 ISO 5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2B6 protein
[5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2B6 protein] which results in decreased metabolism of Bupropion		 CTD PMID:26599973 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions
decreases activity		 ISO [5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole CTD PMID:26599973 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 increases metabolic processing EXP CYP2D1 protein results in increased metabolism of 5-methoxy-N,N-diisopropyltryptamine CTD PMID:18191824 NCBI chr 7:113,908,950...113,913,420
Ensembl chr 7:113,908,947...113,922,084 		JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 increases metabolic processing EXP CYP2D2 protein results in increased metabolism of 5-methoxy-N,N-diisopropyltryptamine CTD PMID:18191824 NCBI chr 7:113,935,138...113,939,209
Ensembl chr 7:113,935,138...113,939,209 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions
decreases activity		 ISO [5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan CTD PMID:26599973 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases activity		 ISO [5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone CTD PMID:26599973 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19831
    chemical entity 19829
      atom 19829
        nonmetal atom 19767
          nitrogen atom 18955
            nitrogen molecular entity 18955
              organonitrogen compound 18804
                organonitrogen heterocyclic compound 18148
                  benzopyrrole 9724
                    indoles 9414
                      tryptamines 510
                        N,N-diisopropyltryptamine 7
                          5-methoxy-N,N-diisopropyltryptamine 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19831
    subatomic particle 19829
      composite particle 19829
        hadron 19829
          baryon 19829
            nucleon 19829
              atomic nucleus 19829
                atom 19829
                  main group element atom 19779
                    p-block element atom 19779
                      carbon group element atom 19728
                        carbon atom 19724
                          organic molecular entity 19724
                            organic molecule 19677
                              organic cyclic compound 19490
                                organic heterocyclic compound 18852
                                  organic heteropolycyclic compound 18295
                                    organic heterobicyclic compound 17240
                                      benzopyrrole 9724
                                        indoles 9414
                                          tryptamines 510
                                            N,N-diisopropyltryptamine 7
                                              5-methoxy-N,N-diisopropyltryptamine 6
paths to the root