CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: polyene
Accession: CHEBI:48121
browse the term
Definition: An olefin that contains more than one carbon-carbon double bond.
Synonyms: related_synonym: polyenes
G
Akt1
AKT serine/threonine kinase 1
multiple interactions
ISO
Nystatin inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein]
CTD
PMID:12614848
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
G
Casp8
caspase 8
multiple interactions
ISO
Nystatin inhibits the reaction [resveratrol affects the localization of CASP8 protein]
CTD
PMID:12902349
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
G
Cav1
caveolin 1
multiple interactions
ISO
Nystatin inhibits the reaction [Quercetin affects the localization of CAV1 protein]
CTD
PMID:17876056
NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
G
Cd40
CD40 molecule
increases expression
ISO
Nystatin results in increased expression of CD40 protein
CTD
PMID:16374455
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
G
Cd80
Cd80 molecule
increases expression
ISO
Nystatin results in increased expression of CD80 protein
CTD
PMID:16374455
NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
G
Cd86
CD86 molecule
increases expression
ISO
Nystatin results in increased expression of CD86 protein
CTD
PMID:16374455
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
G
Clu
clusterin
increases expression
ISO
Nystatin results in increased expression of CLU mRNA
CTD
PMID:22863853
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
G
Cp
ceruloplasmin
increases expression
ISO
Nystatin results in increased expression of CP mRNA
CTD
PMID:22863853
NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
G
Fadd
Fas associated via death domain
multiple interactions
ISO
Nystatin inhibits the reaction [resveratrol affects the localization of FADD protein]
CTD
PMID:12902349
NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
G
Fas
Fas cell surface death receptor
multiple interactions
ISO
Nystatin inhibits the reaction [resveratrol affects the localization of FAS protein]
CTD
PMID:12902349
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
G
Fga
fibrinogen alpha chain
increases expression
ISO
Nystatin results in increased expression of FGA mRNA
CTD
PMID:22863853
NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
G
Fgg
fibrinogen gamma chain
increases expression
ISO
Nystatin results in increased expression of FGG mRNA
CTD
PMID:22863853
NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
G
Havcr1
hepatitis A virus cellular receptor 1
increases expression
ISO
Nystatin results in increased expression of HAVCR1 mRNA
CTD
PMID:22863853
NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
G
Icam1
intercellular adhesion molecule 1
increases expression
ISO
Nystatin results in increased expression of ICAM1 protein
CTD
PMID:16374455
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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Il1b
interleukin 1 beta
increases expression
ISO
Nystatin results in increased expression of IL1B mRNA; Nystatin results in increased expression of IL1B protein
CTD
PMID:16374455
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il6
interleukin 6
increases expression
ISO
Nystatin results in increased expression of IL6 protein
CTD
PMID:16374455
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Krt18
keratin 18
increases expression
ISO
Nystatin results in increased expression of KRT18 mRNA
CTD
PMID:22863853
NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
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Krt19
keratin 19
increases expression
ISO
Nystatin results in increased expression of KRT19 mRNA
CTD
PMID:22863853
NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799
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Krt8
keratin 8
increases expression
ISO
Nystatin results in increased expression of KRT8 mRNA
CTD
PMID:22863853
NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
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Lcn2
lipocalin 2
increases expression
ISO
Nystatin results in increased expression of LCN2 mRNA
CTD
PMID:22863853
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
G
Mapk1
mitogen activated protein kinase 1
multiple interactions
EXP
Nystatin inhibits the reaction [4-ethylphenol results in increased phosphorylation of MAPK1 protein]; Nystatin inhibits the reaction [4-propylphenol results in increased phosphorylation of MAPK1 protein]; Nystatin inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK1 protein]; Nystatin inhibits the reaction [Diethylstilbestrol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Nystatin inhibits the reaction [Estradiol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Nystatin inhibits the reaction [Estradiol results in increased phosphorylation of MAPK1 protein]; Nystatin inhibits the reaction [Estriol results in increased phosphorylation of MAPK1 protein]; Nystatin inhibits the reaction [Estrone results in increased phosphorylation of MAPK1 protein]
CTD
PMID:15072920 PMID:22230296
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
G
Mapk3
mitogen activated protein kinase 3
multiple interactions
EXP
Nystatin inhibits the reaction [4-ethylphenol results in increased phosphorylation of MAPK3 protein]; Nystatin inhibits the reaction [4-propylphenol results in increased phosphorylation of MAPK3 protein]; Nystatin inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein]; Nystatin inhibits the reaction [Diethylstilbestrol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Nystatin inhibits the reaction [Estradiol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Nystatin inhibits the reaction [Estradiol results in increased phosphorylation of MAPK3 protein]; Nystatin inhibits the reaction [Estriol results in increased phosphorylation of MAPK3 protein]; Nystatin inhibits the reaction [Estrone results in increased phosphorylation of MAPK3 protein]
CTD
PMID:15072920 PMID:22230296
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Prnp
prion protein
multiple interactions
ISO
Nystatin inhibits the reaction [Copper Sulfate results in increased uptake of and affects the localization of PRNP protein]
CTD
PMID:11994310
NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
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Rel
REL proto-oncogene, NF-kB subunit
increases activity
ISO
Nystatin results in increased activity of REL protein
CTD
PMID:16374455
NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
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Rela
RELA proto-oncogene, NF-kB subunit
increases activity
ISO
Nystatin results in increased activity of RELA protein
CTD
PMID:16374455
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Spp1
secreted phosphoprotein 1
increases expression
ISO
Nystatin results in increased expression of SPP1 mRNA
CTD
PMID:22863853
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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Timp1
TIMP metallopeptidase inhibitor 1
increases expression
ISO
Nystatin results in increased expression of TIMP1 mRNA
CTD
PMID:22863853
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
G
Tnfrsf10b
TNF receptor superfamily member 10b
multiple interactions
ISO
Nystatin inhibits the reaction [Quercetin affects the localization of TNFRSF10A protein]
CTD
PMID:17876056
NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467
G
Vim
vimentin
increases expression
ISO
Nystatin results in increased expression of VIM mRNA
CTD
PMID:22863853
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
CHEBI ontology
19922
chemical entity
19920
atom
19892
nonmetal atom
19849
carbon atom
19802
organic molecular entity
19775
olefinic compound
16967
olefin
8941
polyene
29
(+)-somaliensene B
0
(-)-somaliensene B
0
4,4'-diapo-zeta-carotene +
0
4,4'-diaponeurosporene
0
4,4'-diapophytoene +
0
4,4'-diapophytofluene +
0
4-(1-methyleneallyl)-1,5,5-trimethylcyclopentene
0
aethusin
0
axerophthene
0
beta-elemene +
0
beta-geranylfarnesene
0
beta-heptaprene
0
beta-hexaprene
0
nystatin
29
nystatins +
29
reedsmycin A
0
reedsmycin B
0
reedsmycin C
0
reedsmycin D
0
reedsmycin E
0
reedsmycin F
0
somaliensene A
0
torulene +
0
Path 2
CHEBI ontology
19922
subatomic particle
19892
composite particle
19892
hadron
19920
baryon
19892
nucleon
19920
atomic nucleus
19892
atom
19892
main group element atom
19866
main group molecular entity
19838
s-block molecular entity
19698
hydrogen molecular entity
19679
hydrides
19181
organic hydride
18695
organic fundamental parent
18715
hydrocarbon
18458
olefin
8941
polyene
29
(+)-somaliensene B
0
(-)-somaliensene B
0
4,4'-diapo-zeta-carotene +
0
4,4'-diaponeurosporene
0
4,4'-diapophytoene +
0
4,4'-diapophytofluene +
0
4-(1-methyleneallyl)-1,5,5-trimethylcyclopentene
0
aethusin
0
axerophthene
0
beta-elemene +
0
beta-geranylfarnesene
0
beta-heptaprene
0
beta-hexaprene
0
nystatin
29
nystatins +
29
reedsmycin A
0
reedsmycin B
0
reedsmycin C
0
reedsmycin D
0
reedsmycin E
0
reedsmycin F
0
somaliensene A
0
torulene +
0