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ONTOLOGY REPORT - ANNOTATIONS


Term:anthracycline
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Accession:CHEBI:48120 term browser browse the term
Definition:Anthracyclines are polyketides that have a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine.
Synonyms:related_synonym: anthracyclines
 cyclic_relationship: is_conjugate_base_of CHEBI:64678


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Path 1
Term Annotations click to browse term
  CHEBI ontology 19790
    role 19738
      biological role 19737
        biochemical role 19232
          metabolite 19208
            anthracycline 7347
              (7R,9R)-9-acetyl-7-[[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-2-oxanyl]oxy]-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione 0
              (7R,9S)-9-acetyl-7-[[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-2-oxanyl]oxy]-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 0
              (7S,9S)-7-[(4-amino-5-hydroxy-6-methyl-2-oxanyl)oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 0
              (7S,9S)-7-[[(2R,4S,5S,6S)-4-amino-6-methyl-5-[[(2R)-2-oxanyl]oxy]-2-oxanyl]oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 0
              (7S,9S)-7-[[(4S,5S,6S)-4-amino-5-hydroxy-6-methyl-2-oxanyl]oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 0
              (7S,9S)-9-acetyl-7-[(4-amino-5-hydroxy-6-methyl-2-oxanyl)oxy]-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 0
              (7S,9S)-9-acetyl-7-[(4-amino-5-hydroxy-6-methyl-2-oxanyl)oxy]-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione 0
              1-O-demethyl-6-deoxydoxorubicin 0
              11-deoxy-beta-rhodomycin 0
              13-deoxydaunorubicin 0
              13-dihydrodaunorubicin + 4
              15-Demethoxy-epsilon-rhodomycin 0
              15-demethylaclacinomycin T 0
              2-deoxy-alpha-L-fucosylaclacinomycin S 0
              4'-epidoxorubicin 52
              7-[(4-amino-5-hydroxy-6-methyl-2-oxanyl)oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 0
              9-acetyl-7-[(4-amino-5-hydroxy-6-methyl-2-oxanyl)oxy]-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 0
              Aclarubicin hydrochloride 0
              Daunorubicin hydrochloride 0
              Doxorubicin hydrochloride 0
              Idarubicin hydrochloride 0
              Pirarubicin 9
              aclacinomycin A 12
              aclacinomycin N 0
              aclacinomycin S 0
              aclacinomycin T 0
              aclacinomycin Y 0
              aklavinone + 12
              anthracycline antibiotic + 7312
              beta-Rhodomycin 0
              daunorubicin + 204
              doxorubicin + 7304
              epsilon-Rhodomycin T 0
              nogalamycin 0
              valrubicin 1
              zorubicin 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19790
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19674
                    p-block element atom 19674
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            heteroorganic entity 19158
                              organochalcogen compound 18859
                                organooxygen compound 18776
                                  polyketide 8561
                                    anthracycline 7347
                                      (7R,9R)-9-acetyl-7-[[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-2-oxanyl]oxy]-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione 0
                                      (7R,9S)-9-acetyl-7-[[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-2-oxanyl]oxy]-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 0
                                      (7S,9S)-7-[(4-amino-5-hydroxy-6-methyl-2-oxanyl)oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 0
                                      (7S,9S)-7-[[(2R,4S,5S,6S)-4-amino-6-methyl-5-[[(2R)-2-oxanyl]oxy]-2-oxanyl]oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 0
                                      (7S,9S)-7-[[(4S,5S,6S)-4-amino-5-hydroxy-6-methyl-2-oxanyl]oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 0
                                      (7S,9S)-9-acetyl-7-[(4-amino-5-hydroxy-6-methyl-2-oxanyl)oxy]-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 0
                                      (7S,9S)-9-acetyl-7-[(4-amino-5-hydroxy-6-methyl-2-oxanyl)oxy]-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione 0
                                      1-O-demethyl-6-deoxydoxorubicin 0
                                      11-deoxy-beta-rhodomycin 0
                                      13-deoxydaunorubicin 0
                                      13-dihydrodaunorubicin + 4
                                      15-Demethoxy-epsilon-rhodomycin 0
                                      15-demethylaclacinomycin T 0
                                      2-deoxy-alpha-L-fucosylaclacinomycin S 0
                                      4'-epidoxorubicin 52
                                      7-[(4-amino-5-hydroxy-6-methyl-2-oxanyl)oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 0
                                      9-acetyl-7-[(4-amino-5-hydroxy-6-methyl-2-oxanyl)oxy]-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 0
                                      Aclarubicin hydrochloride 0
                                      Daunorubicin hydrochloride 0
                                      Doxorubicin hydrochloride 0
                                      Idarubicin hydrochloride 0
                                      Pirarubicin 9
                                      aclacinomycin A 12
                                      aclacinomycin N 0
                                      aclacinomycin S 0
                                      aclacinomycin T 0
                                      aclacinomycin Y 0
                                      aklavinone + 12
                                      anthracycline antibiotic + 7312
                                      beta-Rhodomycin 0
                                      daunorubicin + 204
                                      doxorubicin + 7304
                                      epsilon-Rhodomycin T 0
                                      nogalamycin 0
                                      valrubicin 1
                                      zorubicin 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.