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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:azepine
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Accession:CHEBI:48105 term browser browse the term
Synonyms:related_synonym: azepines



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Talipexole dihydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A multiple interactions ISO talipexole inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein] CTD PMID:10742289 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Prl prolactin decreases secretion
multiple interactions
EXP talipexole results in decreased secretion of PRL protein
Aripiprazole inhibits the reaction [talipexole results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [talipexole results in decreased secretion of PRL protein]; talipexole inhibits the reaction [Fenfluramine results in increased secretion of PRL protein]
CTD PMID:1678730 PMID:8613910 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO talipexole inhibits the reaction [Methamphetamine results in decreased activity of TH protein] CTD PMID:9655613 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      atom 19799
        nonmetal atom 19686
          nitrogen atom 18767
            nitrogen molecular entity 18767
              organonitrogen compound 18544
                organonitrogen heterocyclic compound 17661
                  azepine 3
                    2,3,4,5,6,7-Hexahydro-6,7-dimethylcyclopent[b]azepin-8(1H)-one 0
                    2,3,4,5,6,7-Hexahydro-7-methylcyclopent[b]azepin-8(1H)-one 0
                    2,3,4,5,6,7-Hexahydrocyclopent[b]azepin-8(1H)-one 0
                    2,3,6,7-Tetrahydro-7-methylcyclopent[b]azepin-8(1H)-one 0
                    2,3,6,7-Tetrahydrocyclopent[b]azepin-8(1H)-one 0
                    2-Acetyl-1,5,6,7-tetrahydro-6-hydroxy-7-(hydroxymethyl)-4H-azepine-4-one 0
                    5-(6-chloro-3-pyridinyl)-9-azabicyclo[4.2.1]non-4-ene 0
                    6-prop-2-enyl-4,5,7,8-tetrahydrothiazolo[4,5-d]azepin-2-amine 0
                    7-Ethyl-2,3,4,5,6,7-hexahydrocyclopent[b]azepin-8(1H)-one 0
                    Dehydroisochalciporone 0
                    N-(3,4,5,6-tetrahydro-2H-azepin-7-yl)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-amine 0
                    N-[(1S)-1-\{[(3S,4S,7R)-3-hydroxy-7-methyl-1-(pyridin-2-ylsulfonyl)-2,3,4,7-tetrahydro-1H-azepin-4-yl]carbamoyl\}-3-methylbutyl]-1-benzofuran-2-carboxamide 0
                    Talipexole dihydrochloride 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic molecule 19549
                              organic cyclic compound 19343
                                organic heterocyclic compound 18584
                                  organic heteromonocyclic compound 17120
                                    azepine 3
                                      2,3,4,5,6,7-Hexahydro-6,7-dimethylcyclopent[b]azepin-8(1H)-one 0
                                      2,3,4,5,6,7-Hexahydro-7-methylcyclopent[b]azepin-8(1H)-one 0
                                      2,3,4,5,6,7-Hexahydrocyclopent[b]azepin-8(1H)-one 0
                                      2,3,6,7-Tetrahydro-7-methylcyclopent[b]azepin-8(1H)-one 0
                                      2,3,6,7-Tetrahydrocyclopent[b]azepin-8(1H)-one 0
                                      2-Acetyl-1,5,6,7-tetrahydro-6-hydroxy-7-(hydroxymethyl)-4H-azepine-4-one 0
                                      5-(6-chloro-3-pyridinyl)-9-azabicyclo[4.2.1]non-4-ene 0
                                      6-prop-2-enyl-4,5,7,8-tetrahydrothiazolo[4,5-d]azepin-2-amine 0
                                      7-Ethyl-2,3,4,5,6,7-hexahydrocyclopent[b]azepin-8(1H)-one 0
                                      Dehydroisochalciporone 0
                                      N-(3,4,5,6-tetrahydro-2H-azepin-7-yl)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-amine 0
                                      N-[(1S)-1-\{[(3S,4S,7R)-3-hydroxy-7-methyl-1-(pyridin-2-ylsulfonyl)-2,3,4,7-tetrahydro-1H-azepin-4-yl]carbamoyl\}-3-methylbutyl]-1-benzofuran-2-carboxamide 0
                                      Talipexole dihydrochloride 3
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